Abbott subsidiaries

Thoratec is the world leader in mechanical circulatory support with the broadest product portfolio to treat the full range of clinical needs for patients suffering from advanced heart failure. The company's products include the HeartMate LVAS and Thoratec VAD, with more than 20,000 devices implanted in patients suffering from heart failure. Thoratec also manufactures and markets the CentriMag and PediMag / PediVAS product lines. Thoratec is headquartered in Pleasanton, California with facilities in Burlington, Massachusetts; Rancho Cordova, Sunnyvale California; Ann Arbor, Michigan; Huntingdon, Cambridgeshire, UK; and Zurich, Switzerland.

Alere Toxicology has provided excellent substance abuse testing solutions, providing timely and accurate services that deter and detect drug and alcohol abuse. We are a single-source solution for quality analysis that includes laboratory testing services and rapid screening devices. The benefits of partnering with us go beyond science. They are a financially stable, reputable organization that is unique in the industry, delivering breakthrough service options with a human touch. Alere Toxicology is comprised of multiple laboratories within the United States and Internationally that specialize in toxicology testing service, including three laboratories certified by the Substance Abuse and Mental Health Services Administration (SAMHSA), the industry's benchmark certification program.

PBM, based in Cleveland, Ohio, is a web-based application developer that serves online applications for insurance companies, TPA's, MCO's, self-insured and state fund employers, providers, and government agencies. Launched in 1998, PBM has earned notable industry praise and its software is utilized by over 38,000 employers, TPA's, MCO's nationwide. Their vision focuses on how they can use the most powerful and effective technology to build integrated solutions that will help their clients lower costs, improve productivity, increase profits, and meet regulatory or governmental compliance. They will meet the unique and different needs of their clients including insurance companies, employers and third party administrators through the development and deployment of highly productive and flexible software and service solutions. They provide the highest level of client care, customer service, and technical support available and are driven by the changing needs of their marketplace. PBM was founded in 1997 by Gregory Hummer MD and John Guiher MBA CPA and is headquartered in Cleveland, OH, USA.

Inverness Medical (now known as Alere Inc.) is a global provider of advanced consumer and professional medical diagnostic products for a range of disease states and conditions. The company develops new capabilities in diagnosis, monitoring, and health management for sectors such as cardiovascular, respiratory, diabetes, toxicology, autoimmunity, clinical, women's health, and more. Additionally, Inverness Medical offers services for chronic care, wellness, case management, women's health, home monitoring, research, evaluation, and training. Since 2005, Inverness Medical has acquired nearly 20 companies, collectively creating the largest product portfolio in the industry. Inverness Medical is headquartered in Waltham, Massachusetts, USA.

At X Technologies, our focus is to consistently exceed our customers' expectations. We pride ourselves on providing world-class engineering, information technology, information security, program management and repair services to Federal, State and comm...

CardioMEMS is a medical device company that has developed and is commercializing a proprietary wireless sensing and communication technology for the human body. Their technology platform is designed to improve the management of severe chronic cardiovascular diseases such as heart failure and aneurysms. Their miniature wireless sensors can be implanted using minimally invasive techniques and transmit cardiac output, blood pressure and heart rate data that are critical to the management of patients.

Facet Biotech Corporation, a biotechnology company, engages in the identification and development of oncology drugs. Facet was formed through a spin-off of the biotechnology segment of PDL BioPharma, Inc., which was completed on December 18, 2008. It was subsequently acquired by Abbott Labs . The company is headquartered in Redwood City, California. Its products in development include Daclizumab, a monoclonal antibody in Phase IIb clinical studies that binds to the alpha chain of the interleukin-2 receptor on activated T cells; and Volociximab, a chimeric monoclonal antibody in Phase I clinical studies that inhibits the functional activity of a protein in activated endothelial cells. The company is also developing Elotuzumab, a monoclonal antibody in Phase I/II clinical studies, which binds to a cell surface glycoprotein that is expressed on myeloma cells and normal human cells; PDL192, a monoclonal antibody in Phase I clinical study, which binds to the tumor necrosis factor-like weak inducer of apoptosis receptor; PDL241, a monoclonal antibody in the preclinical stage for immunologic diseases; and TRU-016, a small modular immunopharmaceutical protein therapeutic in Phase I clinical studies for the treatment of B-cell malignancies, such as chronic lymphocytic leukemia and non-Hodgkin's lymphoma, as well as autoimmune and inflammatory disease indications. It has collaboration agreements with Biogen Idec Inc.; Bristol-Myers Squibb Company; and Trubion Pharmaceuticals, Inc. Facet Biotech Corporation also has license agreements with Abbott Laboratories, Inc.; Actinium Pharmaceuticals, Inc.; Genentech, Inc.; Ophthotech Corporation; Progenics Pharmaceuticals, Inc.; and Seattle Genetics, Inc.