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Under the new company name Allergan Pharmaceuticals, Inc., adopted in 1950, Bly developed additional products, including a cortisone eye drop, Cortefrin.
In 1950, Gavin S. Herbert, Sr. started a small opthalmic business in a laboratory above one of his Los Angeles drugstores.
Next, came the eye drops in 1953.
In 1957, Gavin Herbert, Jr. was discharged, and Allergan sales had reached $100,000.
A key element of that plan was the advent of Allergan's first national product, Prednefrin, a corticosteroid launched in 1958.
By 1960 Allergan was a million-dollar company and the company moved its operations to a 30,000-square-foot plant in Santa Ana, California.
By 1962 Allergan was a million-dollar company and the company moved its operations to a 30,000-square-foot plant in Santa Ana, California.
Allergan began to develop a global outlook in 1964, when it created its first foreign distributorships in Puerto Rico and Iraq.
In 1965 Allergan established its first foreign subsidiary in Canada.
Toward the realization of that plan, Allergan purchased 24 acres from the Irvine Ranch Company and, in 1968, built its Von Karman production facility on that site.
Eye care products were the company’s primary focus before it went public in 1970.
In 1970, large profits generated by Thorazine had become a double-edged sword when the patent expired, due to SmithKline’s shortsighted lack of investment in research and its failure to develop new ventures.
Soft contact lenses had become available in 1970, and Allergan became a contractual supplier of soft contact lens solutions to industry giant Bausch & Laumb.
In 1971, Allergan went public, erecting its first office building in Irvine, California.
Allergan’s two lens products were Hydrocare (introduced in 1974) and its enzymatic cleaner.
In 1978 Gavin Herbert, Sr., Allergan’s cofounder and chairman, died.
The other predecessor of the current company traces its roots back to 1983 when colleagues Allen Chao and David Hsia formed Watson Pharmaceuticals, a drug development enterprise.
In 1984, according to Industry Week, 120 million Americans suffered from a vision problem, but only 12 percent wore soft contact lenses.
In 1984 the company purchased Laboratories Dulcis du Doctor Ferry, S.A., a French firm specializing in ophthalmic prescription drugs.
By 1987, the $500 million contact lens care market was growing at about 20 to 25 percent annually, and Allergan and its competitors were locked in fierce competition.
1988: Allergan acquires the rights to Botox.
In 1990 Allergan was close to a billion-dollar company, but its stock had fallen from $25 (at the time of its spinoff) to $15 a share.
In 1991, Allergan acquired the company Oculinum, which manufactured products for eye muscle disorders.
The restructuring was publicly lauded when Allergan received the 1991 Optimas Award.
In addition, in 1991 the company's board of directors approved a plan to realign Allergan into market-focus business groups with a regional structure giving the company a global focus on the Americas, Europe, Pan-Asia, and Japan.
Also in 1991, Allergan researcher David Woodward patented a composition that could be used in treating glaucoma.
Allergan’s shareholders, however, passed what became one of the first successful shareholder solicitations by a slight majority (52 percent) at the April 1993 annual meeting.
Because these products accounted for some 60 percent of Allergan’s 1993 sales, such a reduction would seriously impact Allergan’s profits.
In 1994 Allergan acquired the Ioptex Research global intraocular lens product line.
Taking over as chairman was Herbert W. Boyer, a biochemist, member of the Allergan board since 1994, and a founder of Genentech Inc.
The company retained its lens care operations, which received a boost with the 1994 introduction of Complete, a new one-bottle solution.
In 1994, the company that began in a small laboratory above a drugstore was a world leader in eye care, with sales approaching $1 billion.
Among the 1995 acquisitions were Optical Micro Systems, Inc., a maker of cataract surgery equipment; Laboratorios Frumtost, S.A., a Brazilian manufacturer of ophthalmic and other pharmaceutical products; and the worldwide contact lens care product operations of Pilkington Barnes Hind.
In late 1995 Allergan launched Azelex cream for the topical treatment of mild to moderate acne of the skin; the product was well received by the market.
Near Merger with Pharmacia & Upjohn in 1996
Also in 1996 Allergan received FDA approval for the Alphagan ophthalmic solution for the treatment of open-angle glaucoma and ocular hypertension.
Soon thereafter, Allergan announced a restructuring that included the elimination of about 450 jobs and 1996 pretax charges of about $75 million.
In 1997 Allergan expanded its burgeoning skin care line through the FDA approval of Tazorac for the treatment of plaque psoriasis and acne.
Greene, Jay, “Allergan’s Botox, Made from Toxin, Used to Fight Wrinkles,” Orange County (Calif.) Register, February 16, 1998.
Altman, Lawrence K., “Botulinum Toxin’s Promise As Drug May Rival Its Potential As Weapon,” New York Times, March 10, 1998, p.F7.
Meanwhile, in 1998 the company also entered into a multiyear alliance with the Parke-Davis Pharmaceutical Research Division of Warner-Lambert Company to investigate retinoids for the treatment of metabolic diseases.
The company in 1998 also contributed $200 million to a new subsidiary, Allergan Specialty Therapeutics, Inc. (ASTI), which was then spun off to shareholders as a dividend.
In April 1999 a seemingly revitalized Allergan announced a $70 million expansion of its R&D campus at the Irvine headquarters and the addition of 300 new research scientists and other professionals.
With more than 17 000 employees, Allergan Plc is considered one of the top 2000 largest public companies in the world, according to Forbes.
A much more significant deal occurred in June 2002 when the company spun off its ophthalmic surgical and contact lens care unit to shareholders, creating a newly independent, public company called Advanced Medical Optics, Inc.
One factor driving these figures was the securing in 2002 of FDA approval for cosmetic use of Botox, specifically to temporarily relieve brow furrows.
The expansion was slated for completion in 2004.
Allergan enjoyed its best year yet in 2004 as sales surpassed the $2 billion mark, and profits were a record $377.1 million.
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Any launch of Reloxin, however, was not expected until 2008 at the earliest.
Allergan acquired the Seri Scaffold technology when it purchased its original maker Serica in 2010.
In 2010, Allergan agreed to pay $600 million to the federal government to resolve allegations of off-label promotion of the drug, according to the United States Department of Justice.
Reuters. (2011, April 28). Jury orders Allergan to pay $212 million in Botox case.
On October 31, 2012, Watson acquired Actavis for €4.25 billion and took the Actavis name.
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The Associated Press. (2015, April 14). Botox maker sued over Vermont woman’s death.
The company acquired a newly found firm called ‘Oculeve’ in June 6, 2015.
In October 2015, there were plans for a merger with Pfizer Inc., but that simply could not be completed due to the intervention of the erstwhile President Barack Obama regarding the prevention of alleged tax violations.
In August 3, 2016, the major subsidiary, ‘Anda Inc’ was sold to Teva Pharmaceutical Limited.
In November 2016, the purchase of ‘Chase Pharmaceuticals’ was completed.
2016 Teva Pharmaceuticals bought Actavis generics.
2017 Botox revenues reached $2.2 billion.
Ramsey, L. (2018, June 2). How Allergan went from a tiny but beloved Southern California eye care company to a dealmaking machine to falling out of grace with investors.
The United States Attorney’s Office in Boston was asked to reopen a criminal case against the drug maker in early 2018.
2018 Allergan announced its plan to sell its women’s health and infectious disease businesses.
On May 8, 2020, the United States pharmaceutical company AbbVie acquired Allergan for $63 billion, and return Allergan to the United States for tax purposes.
"Allergan, Inc. ." International Directory of Company Histories. . Retrieved May 23, 2022 from Encyclopedia.com: https://www.encyclopedia.com/books/politics-and-business-magazines/allergan-inc-1
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| Company name | Founded date | Revenue | Employee size | Job openings |
|---|---|---|---|---|
| Merck | 1891 | $64.2B | 74,000 | 2,455 |
| Hospira | 2004 | $4.5B | 19,000 | - |
| Vertex Pharmaceuticals | 1989 | $11.0B | 3,400 | 128 |
| Zoetis | 1952 | $9.3B | 11,300 | 232 |
| Johnson & Johnson | 1886 | $88.8B | 134,500 | 1,530 |
| Amgen | 1980 | $33.4B | 22,000 | 680 |
| Gilead Sciences | 1987 | $28.8B | 11,800 | 722 |
| Regeneron | 1988 | $14.2B | 9,123 | 354 |
| Seagen | 1997 | $2.0B | 900 | - |
| Boehringer Ingelheim | 1984 | $17.2B | 52,391 | 400 |
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Allergan plc may also be known as or be related to ALLERGAN INC, Allergan, Allergan Inc, Allergan plc and Forsight Vision4, Inc.