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Alnylam Pharmaceuticals company history timeline

2002

In 2002, Alnylam was founded by scientists Phillip Sharp, Paul Schimmel, David Bartel, Thomas Tuschl, and Phillip Zamore, and by investors Christoph Westphal and John Kennedy Clarke; John Maraganore was the founding CEO. The company was named after Alnilam, a star in Orion’s belt.

2003

In 2003, the firm merged with the German pharmaceutical company, Ribopharma AG. The newly formed company also received $24.6 million in funding from private-equity firms.

2004

On February 27, 2004, Alnylam Pharmaceuticals filed for an IPO. The company raised $26 million and began trading as ALNY on the Nasdaq stock exchange.

2007

In 2007, it entered into a nonexclusive alliance with Hoffmann-La Roche, in which Alnylam received $331 million in exchange for access to its technology platform. and also partnered with Isis Pharmaceuticals to found the company Regulus Therapeutics, focused on microRNA therapeutics.

2009

In 2009, the company formed alliances with Cubist Pharmaceuticals and Kyowa Hakko Kirin to market a drug targeted at respiratory syncytial virus.

2011

Alnylam has now exceeded its goals from the first two such plans, growing its market cap from $416 million at the start of 2011 to over $13 billion today.

In 2011, it partnered with GlaxoSmithKline to develop RNAi technology enhancing vaccine production.

2012

In 2012, it formed a partnership with Sanofi Genzyme to develop a treatment for transthyretin-mediated amyloidosis, a hereditary disease in Asia.

2013

In February 2013, it formed a partnership with The Medicines Company to develop a drug to treat a genetic form of high cholesterol.

2014

In 2014, Sanofi Genzyme acquired a 12 percent stake in Alnylam and increased its rights to several of the company's drugs for $700 million.

2015

In 2015, the company had $41 million in revenue and a market cap of $5.2 billion.

2016

In 2016, the company purchased land in Norton, Massachusetts to build a manufacturing facility.

2020

In February 2020, Alnylam appointed former Sanofi CEO Olivier Brandicourt to its board of directors.

It employs more than 1,500 employees, the vast majority of which are in Massachusetts, and while the company is not yet profitable, it ended 2020 with product revenue of $306 million.

2021

On December 22, 2021, Novartis announced that the US Food and Drug Administration (FDA) approved Leqvio (inclisiran), a small interfering RNA (siRNA) therapy to lower low-density lipoprotein cholesterol.

Top-Ranked company for 2021: Collegium Pharmaceuticals

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Founded
2002
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Headquarters
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Founders
Amy W. Schulman,Phillip A. Sharp,John K. Clarke,David Bartel,Paul Schimmel,Phillip Zamore,Robert Langer,Thomas Tuschl
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Alnylam Pharmaceuticals may also be known as or be related to Alnylam Pharmaceuticals, Alnylam Pharmaceuticals Inc, Alnylam Pharmaceuticals Inc. and Alnylam Pharmaceuticals, Inc.