Alnylam Pharmaceuticals jobs in Cambridge, MA - 345 jobs

A global biotechnology company is looking for an Associate Director of US Pain Social Media Marketing in Boston. This role involves leading the development of digital patient engagement and executing social media strategies to reach and empower patients. Candidates should have over 7 years of experience in digital marketing, particularly in social media, and the ability to manage cross-functional teams. This is a hybrid position offering a salary range of $162,800 to $244,200, alongside comprehensive benefits. #J-18808-Ljbffr

Senior Medical Science Liaison - Nephrology (Michigan: East) page is loaded## Senior Medical Science Liaison - Nephrology (Michigan: East)locations: Boston, MAtime type: Full timeposted on: Posted Todayjob requisition id: REQ-26679**Job Description****General Summary:**The Senior Medical Science Liaison (Sr MSL) (Nephrology) for Povetacicept programs. Povetacicept (pove) is an enhanced, dual BAFF/APRIL inhibitor in pivotal development for the treatment of IgA Nephropathy (IgAN).The Sr MSL will serve as a scientific liaison to the medical/academic community and is responsible for establishing and maintaining relationships with Health Care Providers/Professionals (HCPs) to ensure the appropriate dissemination of clinical and scientific information regarding Vertex' compounds in a timely, ethical and stakeholder-focused manner. The Sr MSL will contribute to shaping the medical plan by providing external stakeholders' insights and contribute to the designing and execution of the Medical Affairs strategy and plan. The Sr MSL will engage HCPs in response to scientific educational and research needs with available Vertex resources and provide the latest emerging data in response to specific inquiries, as appropriate.**Key Duties and Responsibilities:*** Develops and fosters effective and trusting relationships with Thought Leaders (TL) and identifies and engages other appropriate HCPs resulting in scientific engagement with a large network of T1D and transplant-team care providers and opinion leaders. Additionally, understands the inter-relationships both within and between academic centers and utilizes this expertise to enhance Thought Leader and HCP engagements* Consistently incorporates all aspects of the SEM (Scientific Engagement Model) into all interactions, enhancing the quality of interactions and overall relationships as assessed by field coaching observations* Independently incorporates the medical plan into interactions and territory planning (i.e. listening priorities) and captures valuable feedback in the CRM system to inform internal stakeholders and assist in shaping the medical strategy* Possesses an in-depth understanding of the utility and functionality of the CRM system/data analytics tools, allowing for the time sensitive capture of interaction details. Uses CRM/Analytics to enhance future TL engagements and manage workload* Discusses scientific information effectively and compliantly with external stakeholders at an advanced level of communication for both disease state and product to external stakeholders as assessed by management coaching and field observations* In-depth conceptual and practical knowledge of payers in the region and possesses an in-depth understanding of the impact of payers on patient care delivery* Assists clinical development/clinical operations by fully understanding IB content and presenting IB material, providing nominations for trial sites as requested, providing end of study data reviews with investigators (as needed)* Represents Vertex at medical congresses by providing scientific session/abstract coverage, booth staffing coverage, routine TL interactions, contributing to the daily and end of congress summaries and may provide logistical guidance through organizing and scheduling abstract/session coverage and preparing and delivering the conference debrief (as needed)* May serve as a mentor or trainer for colleagues with less experience; for example, assisting with new hire MSL onboarding* Conducts all activities in compliance with Vertex policy and procedures and performs all administrative tasks in a timely manner such as CRM entry, vehicle mileage reporting, expense reporting, calendar entries, training assignments, etc.**Knowledge and Skills:*** Ability to complete goals within allotted timeframes, and deliver high quality results* Ability to help plan and complete projects in a constantly changing field-based environment* Ability to appraise and comprehend medical and scientific literature* Ability to effectively present clinical/scientific information in a credible manner in varied settings* Good knowledge of assigned geographic territory* In-depth understanding of healthcare regulatory environment* Apply proficient knowledge of relevant T1D and T1D management protocols, healthcare environment and landscape to articulate the medical and scientific value of our products* Demonstrated working understanding around the compliance and regulatory frameworks that govern the pharmaceutical industry and conducts compliant interactions with internal and external stakeholders.* In-depth knowledge of payers and unique medical information needs to support access and appropriate use of Vertex medicines* Good knowledge of Health Economics and Outcomes Research* Fluent in English (oral and written)**Education and Experience:*** Minimum requirement for advanced biomedical or life sciences degree (ex. Masters, NP, PA)* Requires minimum of 3-4 years of experience as an MSL supporting Nephrology programs or in other medical affairs roles in the pharma/biotech industry or the equivalent combination of education and experience.* Previous training or experience in designated therapeutic area is helpful Pay Range:$171,300 - $245,000Disclosure Statement:The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.**Company Information**Vertex is a global biotechnology company that invests in scientific innovation.Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com. #J-18808-Ljbffr

A leading biotechnology company is seeking an Associate Director, Global Pain Market Research to join its Boston team. In this role, you will oversee commercial insights supporting the Global Commercial Strategy for pain management. Key responsibilities include designing primary market research and developing the annual situation analysis. Candidates should have a Bachelor's degree and 8+ years of relevant experience in market research and bio-pharma marketing. Flexible work options are available. #J-18808-Ljbffr

Are you ready to revolutionize Cell & Gene Therapy? Join us in shaping the future of therapeutics! We are seeking a Senior Mechanical & Automation Engineer in our journey of developing cutting‑edge manufacturing solutions for Casgevy-a first‑of‑its‑kind therapy transforming the treatment of Sick Cell Disease and Beta Thalassemia. In this role, you will be at the forefront of automating complex processes in one of the most dynamic and rapidly evolving fields in biotechnology. By leveraging your expertise in mechanical engineering and automation, you will play a pivotal role in streamlining manufacturing, enhancing manufacturing reliability, and scaling life‑saving therapies to reach patients faster. You will work with a passionate team of scientists, engineers, and innovators, all united by a shared mission: to push the boundaries of what's possible in Cell & Gene Therapy. This role reports to the Associate Director of Automation, Equipment, and Processes. Key Responsibilities Development of industrial machinery and automation from concept through commercial deployment. Manage the evaluation and selection of new equipment/technologies or modifications to existing systems required for scale up. Mechanical Design and integration, including, but not limited to robotics, single‑use sets, single‑use set cartridges, conveyors, AGV/AMRs, cam‑followers, peristaltic pumps, pinch valves, MFCs, solenoid valves, and process analytical technologies, and more. Mechanical Design Analysis, including, but not limited to kinematic design & analysis, dynamic analysis, stress analysis, tolerance stack analysis, mechanism design, cycle time calculation, utilization calculations, and cam‑follower design. Aseptic and GMP design. Design for compatibility with cleaning and sterilization. Single Use Set Design experience. Interface and collaborate with controls resources for joint electro‑mechanical designs. Manage vendors and perform design reviews, FATs, and SATs. Support validation activities. Create a scale up plan from concept through commercial equipment deployment. Provide support to non‑engineering Staff, including those from R&D and Manufacturing, to ensure successful technology transfer and continuous improvement. Support optimization and improvement in equipment/systems/processes. Establish equipment documentation, including parts lists, mechanical drawings, and assembly drawings. Provide engineering change documentation as appropriate. Statistically characterize equipment performance and implement designs to ensure repeatability and consistency. Design and manage vendor design of 3D CAD models. Collaborate with vendors to produce prototype and production parts. Create Equipment layouts in AutoCAD and/or Revit. Create drawings to ASME Y14.5M-200977. Understand and apply other respective standards within machine design, including ANSI and ISO standards. Provide hands‑on troubleshooting, equipment, and manufacturing assistance in support of a rapid development cycle and manufacturing sustainability. Execute assigned duties on time and within budget; proactively communicate delays and other issues to relevant stakeholders. Comply with all regulatory, corporate, and Quality System policies. Support Deviation Management, CAPA, and Change Control activities, as required. Perform other duties as assigned. Required Qualifications BS or MS in engineering or another relevant discipline. 5+ years of experience working within an automation development environment (pharmaceutical, cGxP preferred). Experience with cell & gene therapy is highly desirable. Experience working with a variety of automation hardware, including but not limited to custom‑fabricated mechanical components, cam systems, linkages, index and dwell machines, cartesian robots, SCARA robots, end‑of‑arm tooling, and dip coating. Experience developing single‑use sets. Understanding of cGxP principles and practices and familiarization with ISO 13485, ISO 14971, and 21CFR820 is a plus. Knowledge of global cGMP requirements governing device or combination products. Experience with 3D CAD software, preferably with SolidWorks. Experience troubleshooting industrial automation. A strong understanding of statistical principles is required, as are strong technical writing and presentation skills. Must be able to work independently with adequate supervision, multi‑task, and support several projects simultaneously. Sense of urgency, ability to act/escalate promptly, and transparently communicate issues to involved stakeholders and management. Must demonstrate strong interpersonal, presentation, and teamwork skills. This is a 5 days a week role, requiring 3 days onsite per week at our Boston and Rhode Island offices. Pay Range $75/hr - $90/hr. Shift/Hours Monday-Friday Requisition Disclaimer This job posting is for a temporary role with a third‑party agency partner on assignment at Vertex Pharmaceuticals (“Vertex”). The individual selected for this role will be offered the role as an employee of a third‑party agency partner; compensation, medical benefits, fringe benefits and other terms and conditions of employment shall be presented by the third‑party agency partner upon offer. The pay rate range provided is a reasonable estimate of the anticipated compensation range for this job at the time of posting. The actual pay rate will be based on a number of factors, including skills, competencies, experience, location and other job‑related factors permitted by law. In addition, this role will be eligible for overtime pay, in accordance with federal and state requirements. No C2C or Third‑Party Vendors. #J-18808-Ljbffr

A leading healthcare firm is seeking a Senior Medical Science Liaison based in the Boston area. This role involves providing scientific information to healthcare providers and requires strong experience in immunology. Candidates should have a PharmD, PhD, or MD with at least 3 years in related fields. The position emphasizes relationship-building and territory planning, with a travel requirement of up to 70%. Competitive compensation and benefits are offered. #J-18808-Ljbffr

A global biotechnology company is seeking a Policy & Alliance Development Director to build policy initiatives and strategic alliances focusing on kidney disease. The role involves developing reimbursement strategies and managing partnerships with patient organizations. Ideal candidates will have extensive experience in public policy, government affairs, and a Bachelor's degree. A hybrid work model is available, with competitive compensation between $204,600 and $307,000 annually. #J-18808-Ljbffr

A leading biotechnology firm is seeking a Clinical Imaging Scientific Director for Oncology to lead imaging strategy and execution in clinical trials. The ideal candidate will have a PhD and over 10 years of experience in clinical imaging, particularly in oncology, with significant expertise in PET imaging and regulatory engagement. This role requires collaboration with research teams and overseeing imaging project implementation, contributing significantly to oncology drug development. Comprehensive benefits are offered to eligible employees. #J-18808-Ljbffr

A leading global biotechnology firm in Boston seeks a Principal Engineer to lead the automation of pre-clinical data pipelines and regulatory reporting solutions. This role focuses on driving modernization and standardization initiatives, leveraging AI technologies, and enhancing data consumption practices. Candidates should possess strong programming skills and a degree in a relevant field, with a minimum of five years in technical leadership within the biotechnology industry. The position offers a hybrid work model and a comprehensive benefits package. #J-18808-Ljbffr

A leading biotechnology company is seeking a Director, Global Process Excellence to enhance finance systems and processes integral to scaling operations. This role requires extensive finance experience, capability in project management, and leading cross-functional improvements. The position offers a hybrid work model and competitive salary range of $180,800 - $271,100, along with generous benefits and annual bonus eligibility. #J-18808-Ljbffr

Associate Director, Cell & Gene Therapies External Manufacturing Operations - Commercial Manufacturing & Supply Chain, Vertex Pharmaceuticals (based in US, New England) The primary focus of the Associate Director, External Manufacturing role is to oversee Vertex's critical cell and gene therapy Contract Manufacturing Organizations (CMOs) and implement our vision for this business-critical function. We are looking for a candidate with the breadth of professional experience and the drive to work with both internal and external partners to define and manage the ongoing cGMP supply of cell and gene therapy products from clinical through post-approval lifecycle management. The right candidate should have the ability to understand the challenges and make proactive decisions after anticipating cross-functional and patient impact. The successful candidate should have a strong operational, quality, compliance and technical background, with proven project management and supplier management abilities. The candidate will be located either at the cell and gene therapy CMO's site and/or be able to travel up to 50% of their time to those sites as a "Person-in-Plant" to oversee activities on the ground, and/or as a SME to provide technical support to resolve emerging issues. The successful candidate will be a key member of the Vertex/CMO Virtual Plant Team (VPT) contributing to the broader External Manufacturing group activities. Key Responsibilities: * Function as the first/primary point of contact for all Vertex interests/activities at ATMP cell and gene therapy Contract Manufacturing Organizations (CMOs) * Provide operational oversight of, and troubleshooting support to, CMOs to ensure all deliverables meet or exceed Vertex and regulatory requirements (including but not limited to successful execution of manufacturing operations, on-time shipments, quality compliance and cost management); be Vertex's "eyes and ears" at the CMO for right-first-time execution of commercial operations. * Proactively "connect the dots" on emerging trends and issues and lead/influence cross functional teams to drive resolutions and minimize impact to compliance and delivery of safe and reliable supply * Maintain on-site presence at CMO facilities for extended periods (including off hours/weekends) to oversee (i) critical program activities, (ii) clinical and commercial batch manufacturing until the CMO is sustainably executing operations, and (iii) Health Authority inspections. * Leverage Technical, Quality and Regulatory SMEs to provide guidance to CMOs and ensure cross-functional alignment on program priorities and deliverables from clinical through commercial manufacturing and supply. * Liaise closely with internal and CMO stakeholders and leadership to drive Vertex business operations priorities including but not limited to (i) contract management (including tracking KPIs and metrics e.g. for batch release, inventory targets and schedule attainment), (ii) forecast communication and schedule alignment, (iii) supplier governance (including Vertex Quality/other audits) and (iii) finance (e.g. issuance of POs and reconciliation/validation of invoices; tracking of spend vs budget). * Manage and track CMO performance prior to (preparation), during (direct oversight) and after (campaign summaries/reports) manufacturing. * Manage and track batch data in appropriately compliant (data-integrity) systems to support filing submissions, patient planning and process optimization. * Work closely with CMO and internal Quality and Technical teams to prioritize, monitor, track, review and deliver required compliance documentation (including but not limited to change controls, investigations and deviations, batch data, CAPA effectiveness, internal/external audit observation deadlines, regulatory commitments) to meet Vertex program requirements. * Identify and escalate business-critical issues to Commercial Manufacturing and Supply Chain, CMC, and Quality leadership. * Collaborate with CMO and internal stakeholders to understand planned changes and manage the end-to-end implementation of agreed changes including but not limited to change controls and impact assessments. * Lead continuous improvement initiatives to affect timely resolution of supply issues. * Build and maintain strategic relationships within the CMO organization as well as key internal stakeholders. Minimum Requirements: * Bachelor's degree required, ideally in cell biology, or closely related in Life Sciences disciplines (Immunology, Microbiology, Cell Biology, Engineering, etc.) with 10+ years of relevant experience in biotech or pharmaceutical industries, ideally in a senior manufacturing/operations leadership role working with or in cGMP facilities within the biotechnology industry. * Strong quality and compliance background in a commercial GMP biopharmaceutical operations (manufacturing and quality) environment; sound working knowledge of health authority regulations. * Strong technical background in aseptic manufacturing operations. * Solid project management skills and experience managing complex projects. * Strong verbal and written communication skills: ability to express oneself clearly and concisely, by adjusting style, language and/or terminology as appropriate for the audience. * Strong leadership and an innate ability to collaborate and build relationships is critical. * Ability to work calmly and make sound decisions in a fast-moving environment of uncertainty and change * Flexibility to work shift hours required to cover critical process steps * Ability to travel, national and international, up to 50% * Excellent computer skills including Microsoft (Word, Excel, Project, Outlook, Teams), equipment interfaces and electronic quality systems Desired Additional Skills: * Strong technical background in cell and genetic therapy related manufacturing operations, ideally autologous cell therapy experience. * Solid experience in equipment and facility qualification and validation for ATMP CMO's * Cleanroom qualification (Grade A/B) history Environment: * Office and cleanroom - must be able to comply with cleanroom gowning requirements at CMO * Must be able to remain in a stationary position 50% during cleanroom processing activities * Must be comfortable moving about inside the cleanroom to oversee process tasks * Compressed gasses and LN2 are commonly used in manufacturing operations * Human tissue (e.g. apheresis) and cellular materials are commonly used Pay Range: $160,000 - $240,000 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Remote-Eligible Flex Eligibility Status: In this Remote-Eligible role, you can choose to be designated as: 1. Remote: work remotely five days per week and come into the office on occasion - you're always welcome on-site; or select 2. Hybrid: work remotely up to two days per week; or select 3. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. #LI-Remote Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you'll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We're passionate about innovation, inclusion, and supporting your growth-inside and outside the lab. Why Vertex? Real Projects: You'll work on assignments that make a real impact, not just busy work. Mentorship & Networking: Connect with leaders and peers who want to see you succeed through professional networks, connections, and collaborations that will shape your longer-term career. Flexible & Supportive: We offer flexible work options with Flex @ Vertex and prioritize your wellbeing. Inclusive Culture: Collaboration and inclusion are embedded in everything we do. Career Launchpad: Build skills, explore career paths, and get guidance for your future career. Ready to apply? Submit your application and let's turn possibilities into reality! Your Impact The Vertex Clinical and Quantitative Pharmacology internship program is a multi-week experiential training program for students currently working towards a Doctoral degree in pharmacology or PharmD, or a related field of study. If you are passionate, collaborative, and growth-minded, an internship at Vertex will help you gain meaningful experience in our research functional areas and serve as a launchpad for your career. Important Notice Regarding Internship and Co-op Inquiries At Vertex Pharmaceuticals, we are committed to providing a fair and structured recruitment process for all students interested in internship and co-op opportunities. To ensure consistency and equity, all student applications must go through our Early Talent Acquisition Team. Due to the high volume of interest, we are unable to respond to individual solicitation. Direct solicitation to Vertex employees- including senior leaders via email will result in removal from the recruiting process. We appreciate your enthusiasm and interest in Vertex. To be considered for internship or co-op roles, please apply directly through our official application channels. (************************************************************************** Thank you for respecting our process and helping us maintain a fair experience for all candidates. What you will be doing: The Clinical and Quantitative Pharmacology (CQP) department at Vertex leads clinical pharmacology and clinical modeling & simulation efforts across all disease areas and clinical phases of drug development. There will be two CQP summer internship positions available with the opportunity to work with experienced mentors within CQP. A Vertex CQP summer internship will provide a 12-week hands-on opportunity to experience some of the elements of CQP within drug development. Based on the project, an intern may participate in numerous activities, such as design and conduct of clinical pharmacology studies (e.g., first-in-human, drug interaction, food effect, special populations, ADME), or exploration of drug pharmacokinetic (PK) and pharmacokinetic/pharmacodynamic (PK/PD) relationships and related analyses (e.g. population PK or other advanced modeling). Activities the successful candidate may be involved in include literature research, drafting and reviewing clinical study protocols, reviewing clinical study report sections, creating analysis plans, learning to manipulate and create clinical analysis-ready datasets, build and evaluate models, execute analyses, and prepare informative outputs, graphics, and results representations. During the 12-week appointment, the summer intern will also be exposed to various aspects of the drug development process and thereby gain a view into how the CQP functions fit within broader cross-functional drug development teams that often include preclinical disciplines, clinical development, clinical operations, bioanalysis, biostatistics, and more. Not only will interns learn about their day-to-day responsibilities, but they will interact with scientists from various levels, and with organizational leaders and their teams through a series of Professional Development Workshops that are provided during the summer. Clinical and Quantitative pharmacology activities may include the following (project dependent): Research literature, published studies, and regulatory guidance Learn to work with and manipulate clinical data and data constructs Analyses of data collected from literature or clinical trial PK and/or PK/PD data in NONMEM, R and/or related software Summarize the main findings Prepare presentation(s) for various internal forums What you will need to succeed: Enrolled in a PhD or PharmD program in pharmacology, or a related field of study by Fall 2025. Communicate clearly through verbal and written communication Understanding of drug metabolism, PK, and PK/PD principles Knowledge of protein therapeutics preferred Quantitative and hands-on skills preferred: PK and/or PK/PD analyses Experience with data analysis tools such as R, Phoenix WinNonlin, NONMEM or other programming/software applications Prior industry experience preferred but not required Legal authorization to work in the United States, now and in the future. Please note that Vertex does not provide sponsorship for internships or entry level roles within this part of the organization. You must be available to work full-time, 40 hours per week from May - August 2026 Program Details: Full-time, paid internship $33.00 - 50.00 USD/hour Program Dates: May - August 2026 At Vertex, we believe that when you feel your best, you can perform at your best. That's why our US benefits and global well-being resources are designed to support you. • Free 24/7 onsite gym access and free access to group exercise classes • Subsidized commuter benefits- transit and parking • Provided meals-free breakfast daily! • Career development opportunities and events, including C Suite engagement • Social events-both intern-only and company-wide • Location-specific perks and extras! • Recognition of National Intern Day Equal Opportunities Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Vertex is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements. Accessibility & Accommodations We're focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best. Vertex is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com. Export Control Notice This position may involve access to technology or data that is subject to U.S. export control laws, including the Export Administration Regulations (EAR). As such, employment is contingent upon the applicant's ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements, only individuals who qualify as U.S. persons (citizens, permanent residents, asylees, or refugees) are eligible for this position. For this role, Vertex is unable to sponsor non-U.S. persons to apply for an export control license. This job posting is for a temporary role with a third-party agency partner that provides services to Vertex. The individual selected for this role will be offered the role as an employee of that third-party agency; compensation, medical benefits, fringe benefits and other terms and conditions of employment shall be presented by the third-party agency upon offer. For any questions or concerns, please contact early_***************. Pay Range: $0 - $0 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

A leading biotechnology company in Boston seeks a Senior Director of Global Development FP&A to spearhead financial planning and analysis for clinical trials. The ideal candidate has deep expertise in clinical trial finance, project management, and cross-functional collaboration. Responsibilities include managing complex budgets and providing strategic insights to senior leadership. This hybrid-eligible role offers a competitive salary and benefits package. #J-18808-Ljbffr

A leading biotechnology firm in Boston seeks a Senior Mechanical & Automation Engineer. This role involves developing and automating manufacturing solutions for innovative therapies. Candidates should have extensive experience in automation development, mechanical design, and a strong understanding of cGxP principles. This is a five-day-a-week role requiring onsite presence for three days weekly. Compensation ranges from $75 to $90 per hour, with eligibility for overtime pay. #J-18808-Ljbffr

A leading biotechnology company is seeking an Associate Director to drive commercial insights within the North America Commercial organization. The ideal candidate will have a strong background in market research and analytics, with at least 8 years of relevant experience. Key responsibilities include delivering insights to inform marketing strategies and working closely with various business units. This role offers a hybrid work model and competitive benefits. #J-18808-Ljbffr

Johnson & Johnson Innovative Medicines is recruiting for a Senior Medical Science Liaison, Dermatology to be based in the Boston, MA territory. This field‑based clinical role focuses on providing balanced, objective scientific information and education to health care professionals, building strong relationships with opinion leaders, and supporting company research initiatives. The position requires significant travel (estimated 80%) and collaboration across internal and external teams. Responsibilities Develop and execute a strategic territory plan, including in‑person and virtual engagements with health care providers and key opinion leaders. Respond to scientific queries and provide evidence‑based data, integrating real‑world evidence to inform clinical practice. Coordinate and support investigator‑initiated research, including site identification, issue resolution, and meetings. Lead at least one scientific or strategic project in Immunology, identifying educational gaps and elevating team knowledge. Provide regional support to enhance sales training initiatives and improve field personnel competencies. Maintain accurate administrative requirements (expense reporting, activity documentation) and comply with regulatory and health‑care guidelines. Qualifications Advanced medical degree (PharmD, PhD, MD, NP, PA) with a minimum of 3 years of relevant therapeutic area clinical experience. At least 3 years of MSL or related pharmaceutical experience, including significant presentation experience. Strong communication, stakeholder engagement, and scientific dissemination skills. Valid U.S. driver's license with a clean record and ability to travel 75‑80% of the time. Residence within the assigned Boston, MA territory. Preferred Knowledge of dermatology or related immune‑mediated disorders. Proficiency with Microsoft Office (Word, Excel, PowerPoint) and remote collaboration tools. Prior experience collaborating with medical affairs, R&D, or field teams. Salary & Benefits Base salary range: $137,000 to $235,750 per year. Eligible for an annual performance bonus and company vehicle through the Fleet Program. Benefits include medical, dental, vision, 401(k) retirement plan, short‑ and long‑term disability, and paid time off. Travel Estimated travel: 80% within the Boston region, with occasional out‑of‑region visits. Equal Opportunity Employer Johnson & Johnson is an Equal Opportunity Employer committed to diversity and inclusion. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status, or other protected characteristics. #J-18808-Ljbffr

A global biotechnology company is seeking a Senior Manager for their Order to Cash function to drive cash flow optimization and manage credit control. This role requires excellent stakeholder management and financial analysis skills. The successful candidate will work closely with various teams, present updates to senior leadership, and have opportunities for personal development in a hybrid-eligible environment. Experience in pharmaceutical or large organizations is preferred. #J-18808-Ljbffr

Ironwood Pharmaceuticals is a leading gastrointestinal (GI) healthcare company on a mission to advance the treatment of GI diseases and redefine the standard of care for GI patients. One of the focus areas is on discovering, developing, and commercializing innovative treatments for patients with severe, rare conditions for which there is a significant unmet medical need. These conditions are challenging to diagnose, often devastating, and have limited, if any, treatment options. The lead product candidate, apraglutide, is a next-generation, best-in-class, synthetic peptide analog of glucagon-like peptide-2, or GLP-2, and is in Phase 3 for the treatment of patients with short bowel syndrome, or SBS, a malabsorption disorder caused by the loss of functional small intestine. It is an exciting time to join as Phase 3 is underway and the company is preparing for an initial launch in the coming years for which it is building out a commercial presence. The Senior Director of Medical Writing will have responsibility for executing a fit-for-purpose delivery model to produce a range of high quality clinical and regulatory documents to advance company goals across all investigational and marketed products. To achieve that aim, the Senior Director will collaborate with stakeholders across the Research & Development organization to understand priorities and needs. The Senior Director will initially oversee the selection and operation of external vendors and may eventually build an internal team to resource projects. The Senior Director will lead the development of processes and initiatives to ensure the consistent delivery of high quality, efficient medical writing services that comply with regulatory and internal guidelines. The Senior Director will represent the medical writing function on cross-functional teams for marketed and/or investigational products. The Senior Director will independently deliver clinical and regulatory documents that span the drug development lifecycle. The Senior Director will ensure high quality with regard to compliance with regulatory and internal guidelines, and the accuracy, consistency, and organization of documents. The Senior Director must be a proactive leader, effectively able to organize and collaborate with cross-functional teams to produce on-time, on-target documents that further the program goals. The Senior Director must have a strong understanding of drug development, clinical research concepts and data interpretation and presentation. Responsibilities: Maintain a long-term project forecast and resource plan to deliver all the documents required to advance company goals. Manage the selection of external vendors, from the initial preparation and review of completed Requests for Proposals through to contract negotiation and finalization. Independently author and manage others in creation of clear and concise, submission-ready clinical and regulatory documents. Manage the ongoing operations of high performing external vendors, including resource forecasting, contract change management, of oversight of vendor financials. Drive the ongoing development of processes, initiative, and tools to improve and enhance operations and to ensure compliance with regulatory standards and ICH/GCP/eCTD guidelines. Serve as a subject matter expert, advising and collaborating with cross-functional stakeholders on document strategy, authoring and review processes, and best practices. Represent Medical Writing and provide medical writing expertise on cross-functional teams. Develop detailed timelines for document development in line with company goals and SOPs. Write clinical and regulatory documents in accordance with applicable guidelines, regulations, practices, and procedures. Documents include, but are not limited to, clinical study protocols, clinical study reports, Investigator's Brochures [IBs], and Module 2 summaries of registration dossiers. Manage multiple rounds of team review through document finalization (ie, distribute documents for review; consolidate and resolve of reviewer comments; lead efficient cross-functional review roundtables). Ensure the accuracy, consistency, and quality of documents. Coordinate a formal quality control (QC) review of documents, as applicable. Coordinate with the Regulatory Operations team to publish documents that meet eSubmission‑ready standards. Collaborate with Data Sciences to review statistical analysis plans to ensure that the outputs planned meet data reporting needs and document templates. Lead the preparation of public disclosures of study results on national registries such as ClinicalTrials.gov and EU Clinical Trials Information System (CTIS), ie, coordinate with the external vendor to prepare the posting, distribute the posting for review, perform a quality control review [QC], consolidate and resolve reviewer comments, coordinate the redaction of required documents, notify the relevant stakeholders, in accordance with the company SOP and relevant regulations. Collaborate effectively across Ironwood and with Ironwood partner companies and external vendors, as applicable. Participate in the development of department SOPs and process-related tools to improve and enhance operations and to ensure compliance with regulatory standards and ICH/GCP/eCTD guidelines. Support medical writing and other cross-functional colleagues as necessary (eg, document review, format, and QC). Qualifications: BA/BS and 12+years of medical writing experience in the pharmaceutical or biotech industry; advanced degree preferred Success in managing resources (internal, external, or hybrid) Prior direct experience leading medical writing teams responsible for global marketing authorization applications Experience with a broad range of clinical regulatory documents spanning the drug development lifecycle Strong understanding of the drug development process, including regulatory requirements and ICH/GCP/eCTD guidelines. Working knowledge of drug development, clinical research, study design, biostatistics, regulatory, and medical terminology Excellent technical writing and editorial skills; excellent attention to detail Strong ability to understand and interpret medical and scientific data Proficient in Microsoft Word, PowerPoint, Excel, Project, and SharePoint Experience with automated document templates (eg, StartingPoint by Accenture), Adobe Acrobat and EndNote Excellent communication, interpersonal, and organizational skills Experience working on cross-functional teams Well organized; able to prioritize tasks, work simultaneously on multiple projects, and complete high-quality documents according to tight timelines Ironwood is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or protected veteran status. Ironwood currently anticipates that the initial base salary for this position could range from between $239,000 to $278,565. The actual base salary will depend, in part, on the successful candidate's qualifications for the role, including education and experience. Ironwood offers a comprehensive compensation and benefits program to eligible employees, including Restricted Stock Unit awards; eligibility to participate in either a bonus or sales incentive program; company-sponsored 401(k) with matching contributions; eligibility for medical, dental, vision and prescription drug benefits; wellness stipends; and a generous vacation/holiday schedule. #LI-Hybrid

Why Sarepta? Why Now? The promise of genetic medicine has arrived, and Sarepta is at the forefront. We hold a leadership position in Duchenne muscular dystrophy (Duchenne) and are building a robust portfolio of programs across muscle, central nervous system, and cardiac diseases. In 2023, we launched our fourth therapy and the first ever gene therapy to treat Duchenne. We're looking for people who see unlimited potential in themselves and who are motivated by an unwavering commitment to patients. What Sarepta Offers At Sarepta, we care deeply about all the people in our community and believe in the importance of supporting them in all aspects of their lives. We aspire to maintain a culture that acknowledges people bring their whole selves to work, and we will strive to help everyone in our community integrate their work and personal lives while maintaining productivity. We are committed to offering a range of benefits and work-life resources designed to support people in the following areas: Physical and Emotional Wellness Financial Wellness Support for Caregivers For a full list of our comprehensive benefits, see our website: ******************************* The Importance of the Role The Director of EHS is a senior leader responsible for shaping and driving Sarepta's global EHS strategy. Reporting to the Vice President of Facilities, Engineering, and Capital Assets, this role will serve as the principal authority on EHS policies, compliance, and risk management across all sites. The Director will lead the development and execution of a comprehensive EHS management system, ensuring alignment with business objectives and regulatory requirements. This position will oversee a growing team of EHS professionals and will be accountable for building organizational capability, fostering a proactive safety culture, and positioning EHS as a strategic partner in business decision-making. The Opportunity to Make a Difference Strategic Leadership: Define and implement a forward-looking EHS vision, strategy, and roadmap that supports Sarepta's business growth and operational excellence. Executive Partnership: Act as a trusted advisor to senior leadership, influencing risk-based decisions and integrating EHS considerations into corporate strategy. Program Development: Establish and maintain a robust EHS management system, ensuring compliance with all applicable laws, regulations, and industry best practices. Team Building: Recruit, develop, and lead a high-performing EHS team, fostering a culture of accountability, innovation, and continuous improvement. Risk Management: Oversee programs for occupational safety, industrial hygiene, environmental compliance, sustainability, and emergency preparedness. Incident Command: Serve as Incident Commander during emergency response and recovery efforts; provide technical expertise for crisis management. Enterprise Oversight: Direct EHS operations across Massachusetts and Ohio sites, with additional support for other business entities as needed. More about You Bachelors degree required, Master's degree in Industrial Hygiene, Occupational Safety, Environmental Science, or related field preferred. Minimum 12-15 years of progressive EHS leadership experience, including at least 5 years in a senior management role within biopharmaceutical or chemical research environments. Professional certifications strongly preferred: CIH, CSP, or CHMM. Deep knowledge of OSHA, NFPA, EPA, and other federal, state, and local regulations. Proven success in implementing enterprise-level EHS systems and programs, including emergency response, hazardous materials management, biosafety, and sustainability initiatives. Exceptional communication and influencing skills, with the ability to engage stakeholders at all levels. Recognized for leadership qualities aligned with Sarepta's core values: Drive, Excellence, Resilience, Teamwork, Innovation, and Compassion. What Now? We're always looking for solution-oriented, critical thinkers. So, if you're comfortable with ambiguity and candor, relish challenging yourself, and place kindness and integrity at the forefront of how you approach your peers and work, then we encourage you to apply. #LI-Onsite#LI-CM1This position requires work on site at one of Sarepta's facilities in the United States.The targeted salary range for this position is $180,000 - $225,000 per year. Sarepta is making a good faith effort to be transparent and accurate around our hiring ranges. The salary offer is commensurate with Sarepta's compensation philosophy and considers factors including, but not limited to, education, training, experience, external market conditions, criticality of role, and internal equity.Candidates must be authorized to work in the U.S.Sarepta Therapeutics offers a competitive compensation and benefit package.Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify.

A leading biotechnology company is seeking a Director of Digital Marketing to drive engagement for their kidney portfolio. You will develop omnichannel strategies, collaborate across teams, and leverage data insights to enhance brand impact. Ideal candidates will have over 10 years in pharmaceutical marketing and proven success in digital campaigns. This position offers a hybrid work option and competitive compensation according to skills and experience, along with extensive benefits. #J-18808-Ljbffr