Associate Scientist jobs at Alpha Consulting

Job Title: Principal Research Scientist VI Pay rate: $120-140/hr on w2 Duration: 12 Months (possible opportunity to convert to perm after contract term) About the Role We are seeking an experienced DMPK Project Representative to provide scientific leadership in the discovery and optimization of small-molecule drug candidates. This role leads DMPK strategy across multiple therapeutic areas and collaborates closely with cross-functional scientific teams. The ideal candidate is an ADME or PK/PD subject matter expert with a strong project-facing background and a track record of impactful scientific contributions. Top Skills 3+ years in a project-facing scientific leadership role Expertise in ADME and/or PK/PD modeling Strong publication/abstract history in metabolism, drug interactions, or PK/PD modeling Key Responsibilities Serve as the DMPK representative on global, cross-functional small-molecule project teams Provide expert guidance on experimental strategy, data interpretation, and DMPK strategy Lead internal and external research efforts supporting drug discovery Work closely with pharmacology, medicinal chemistry, and CRO teams Design, troubleshoot, and interpret complex DMPK experiments (in vitro, in vivo, in silico) Analyze sophisticated datasets and communicate findings to project stakeholders Ensure accurate documentation and contribute to scientific reports, manuscripts, and milestone documents Build collaborations with external scientific partners Represent the organization as a subject matter expert at scientific conferences Qualifications Bachelor's degree with 18+ years experience, OR Master's degree with 12+ years, OR Doctoral degree with 6+ years relevant post-doc/industry experience Deep understanding of ADME principles; PK/PD modeling or biotransformation experience preferred Experience working with outsourced or hybrid ADME models is a plus Strong communication skills-verbal, written, and cross-functional Ideal Candidate You thrive in a scientifically complex, highly collaborative environment and enjoy integrating DMPK strategy to advance drug discovery programs. You're comfortable leading projects, influencing cross-functional teams, and representing DMPK expertise internally and externally.

Established nearly two centuries ago, FM is a leading mutual insurance company whose capital, scientific research capability and engineering expertise are solely dedicated to property risk management and the resilience of its policyholder-owners. These owners, who share the belief that the majority of property loss is preventable, represent many of the world's largest organizations, including one of every four Fortune 500 companies. They work with FM to better understand the hazards that can impact their business continuity to make cost-effective risk management decisions, combining property loss prevention with insurance protection. The purpose of this position is to develop new scientific knowledge, technologies and engineering solutions to problems in material flammability, fire dynamics and Lithium-ion battery safety research, which can be used for the prevention or control of industrial property loss. The principal responsibilities are to carry out research projects in the areas of flammability, fire spread, and heat transfer in fires from solid combustible as well as Lithium-ion batteries. Key areas of research include understanding of fire behavior at the medium and large scales via bench-scale experiments and theoretical models on material flammability and flame heat transfer. Projects can also involve advanced flame diagnostic of buoyant turbulent sooty flames and wall fires. The experimental and theoretical studies will be closely integrated with Computational Fluid Dynamic (CFD) model development and validation within the work group. The position is responsible for all aspects of project management including project proposals, execution, and reporting. The position requires a PhD in Mechanical, Chemical Engineering, Fire Protection Engineering, or related fields with a strong fundamental background in combustion, fluid mechanics, heat transfer, material science and applied mathematics. Extensive experience in experimental methods in thermal fluids, material flammability, heat transfer, combustion/fire, and an understanding of associated numerical methods are required. Research experience with advanced laser diagnostics in flame, experimental measurement in turbulent flame, heat transfer and failure analysis of battery is desirable. Also needed are excellent written and verbal communication skills, as well as demonstrated expertise in developing solutions to challenging technical problems. The final salary offer will vary based on geographic location, individual education, skills, and experience. The position is eligible to participate in FM's comprehensive Total Rewards program that includes an incentive plan, generous health and well-being programs, a 401(k) and pension plan, career development opportunities, tuition reimbursement, flexible work, time off allowances and much more. FM is an Equal Opportunity Employer and is committed to attracting, developing, and retaining a diverse workforce. #FMG #LI-TA1

Established nearly two centuries ago, FM is a leading mutual insurance company whose capital, scientific research capability and engineering expertise are solely dedicated to property risk management and the resilience of its policyholder-owners. These owners, who share the belief that the majority of property loss is preventable, represent many of the world's largest organizations, including one of every four Fortune 500 companies. They work with FM to better understand the hazards that can impact their business continuity to make cost-effective risk management decisions, combining property loss prevention with insurance protection. Join a world-class research team dedicated to reducing the impact of natural hazards and climate risks. FM is a market leader in commercial and industrial property insurance and loss prevention, serving over one-third of FORTUNE 1000 companies with engineering-based risk management and property insurance solutions. FM helps clients maintain business continuity through state-of-the-art engineering and research. The Structures and Geohazards Research Group at FM is seeking a creative and self-motivated Senior Research Scientist with a strong foundation in wind engineering and a specialized focus on computational wind engineering (CWE). The ideal candidate will possess deep expertise in fluid dynamics, high-performance computing, and wind tunnel testing, along with a demonstrated ability to conduct innovative, high-impact research. This role is integral to a strategic research initiative aimed at advancing the understanding of wind-related hazards and developing effective mitigation strategies. The successful candidate will contribute to cutting-edge projects that blend computational modeling with experimental validation to address real-world challenges in wind engineering. Responsibilities: Develop computational fluid dynamics (CFD) models to simulate wind flow around buildings and infrastructure, capturing complex aerodynamic interactions. Analyze wind loading on structures using high-resolution simulations; validate results with wind tunnel experiments or field measurements. Collaborate with interdisciplinary teams to incorporate wind effects into risk models, design standards, and resilience strategies. Publish and present research in peer-reviewed journals and at scientific or industry conferences. Contribute to strategic planning and innovation in wind engineering research initiatives. PhD degree. Mechanical, Civil, Aerospace Engineering or related fields. Hands-on experience with CFD software, both open-source (e.g., OpenFOAM) and commercial (e.g., ANSYS Fluent). Proficient in programming languages such as C++, Python, R, MATLAB. Skilled in high-performance computing (HPC) and parallel computing environments. Experience with wind tunnel testing or field measurements is highly desirable. Familiarity with relevant building codes and standards is a plus. Proven track record of publishing high-quality research and effectively communicating complex technical concepts to diverse audiences.Strong problem-solving abilities, creativity, and the capacity to work independently as well as collaboratively. The final salary offer will vary based on geographic location, individual education, skills, and experience. The position is eligible to participate in FM's comprehensive Total Rewards program that includes an incentive plan, generous health and well-being programs, a 401(k) and pension plan, career development opportunities, tuition reimbursement, flexible work, time off allowances and much more. FM is an Equal Opportunity Employer and is committed to attracting, developing, and retaining a diverse workforce.

Abiologics, Inc. is a privately held, early-stage biotechnology company on a mission to make biology better through an innovative therapeutic modality. We are pioneering the development of Synteins™, a transformational class of macromolecular medicines unlocked by novel synthetic and computational technologies. Abiologics is actively seeking exceptional scientists who are passionate about driving therapeutic modality innovation in biotechnology. Abiologics was founded in Flagship Pioneering's venture creation engine, where companies such as Moderna Therapeutics (NASDAQ: MRNA) and Generate Biomedicines were conceived and created. Since Flagship's founding in 2000, the firm has originated and fostered the development of more than 100 scientific ventures resulting in more than 500 issued patents and more than 50 clinical trials for novel therapeutic agents. THE ROLE We are seeking a biochemist to design, develop, and execute biochemical and biophysical strategies that enable the discovery and optimization of Synteins. The ideal candidate brings hands-on expertise in assay development, primary and secondary biochemical screening, and orthogonal biophysical characterization to establish target engagement, binding kinetics/thermodynamics, and mechanism of action. This role is highly collaborative, partnering closely with medicinal chemistry, computational sciences, and pharmacology. KEY RESPONSIBILITIES Design, develop, and validate robust biochemical and biophysical assays for hit identification, hit triage, and lead optimization across diverse target classes (enzymes, PPIs, receptors, and challenging targets). Execute and analyze small- to medium-scale screens including development of counterscreens and artifact mitigation strategies. Perform quantitative biophysical characterization of ligand-target interactions, including affinity, kinetics, stoichiometry, and thermodynamics. Apply a range of techniques such as SPR/BLI, fluorescence-based assays, and mass-spectrometry based assays; leverage orthogonal methods to confirm binding and establish MOA. Ensure data quality and rigor through appropriate controls, reference standards, Z' factor assessments, and comprehensive data QC and troubleshooting. Miniaturize and automate assays as appropriate; partner with automation/HTS teams and operate plate readers and liquid handling platforms. Analyze, visualize, and interpret complex datasets; summarize findings and recommend next steps to project teams. Proactively evaluate new technologies and methods to improve throughput, sensitivity, or mechanistic insight. Maintain accurate electronic lab notebooks, author SOPs, and present results to cross-functional stakeholders. PROFESSIONAL EXPERIENCE & QUALIFICATIONS PhD in Biochemistry, Biophysics, Chemical Biology, or related field with 0-1+ year of relevant experience; or MS with 6+ years; or BS with 8+ years in industry or equivalent. Demonstrated, hands-on experience developing and running biochemical and/or biophysical assays to quantify ligand binding and target engagement. Proficiency with core biophysical platforms (preferably BLI/SPR) and biochemical readouts (e.g., FP, TR-FRET/HTRF, AlphaLISA, enzymatic kinetics). Track record of troubleshooting complex assay and protein reagent issues and delivering decision-enabling data on tight timelines. Excellent communication and collaboration skills; ability to work effectively in cross-functional, fast-paced environments. LOCATION: Boston, MA ABOUT FLAGSHIP PIONEERING: Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity's most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE's “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company's annual list of the World's Most Innovative Companies. Learn more about Flagship at *************************** At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact. We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship. Recruitment & Staffing Agencies : Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto. #LI-MB1 The salary range for this role is $96,000 - $126,500. Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. Abiologics, Inc currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Abiologics, Inc's good faith estimate as of the date of publication and may be modified in the future.

Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost. Job Description The Respiratory Science group is looking for a highly motivated associate scientist with experience in electrophysiology to be part of a team committed to finding treatments for cystic fibrosis, COPD and other respiratory diseases. The successful candidate will be primarily responsible for primary cell culture (experience with aseptic technique is required), developing and conducting in vitro electrophysiological assays focused on ion transport and its roles in the airway. You will also be involved in new drug target identification and validation as well as investigating the mechanism of action of potential drug candidates. We are looking for a candidate who can utilize their strong technical and organizational skills and has an enthusiastic, collaborative spirit. Additional responsibilities include: 1) Manage laboratory resources, i.e. reagents and supplies, performing routine maintenance and calibration etc. 2) Analyze, interpret and present your results, participate in meetings with team members and other research staff to evaluate, interpret and quality-control the data you generate as well as to identify next steps 3) Learn new techniques and approaches as required to tackle key scientific questions. 4) Recognize and troubleshoot data anomalies to maintain high data quality Minimum requirements: • Bachelors or Master's degree in Biology, Biophysics or related discipline • A minimum of two years of laboratory-based industrial or academic experience and/or training • Previous exposure to in vitro electrophysiology (high throughput platforms and/or ussings would be preferred) • Experience working with human primary cell cultures and other cell lines • Self-motivated and pro-active attitude, with the ability to multi-task • Solid work ethic and demonstrated record of productivity and high quality data • Intermediate/advanced ability with MS Office, especially Excel, and ability to learn new software • Excellent problem solving, organizational and experimental management skills • Strong written and verbal communication skills • Commitment to help the team achieve deliverables and meet aggressive timelines • Ability to be both independent as well as effectively interact with team members and work in a highly dynamic and collaborative environment Additional, highly desirable qualifications: • Experience with cell-based high throughput screening assays • Familiarity with basic statistical analyses and how to apply them to biological data • Flexibility and willingness to occasionally adjust your hours as required by specific experiments Qualifications Minimum requirements: • Bachelors or Master's degree in Biology, Biophysics or related discipline • A minimum of two years of laboratory-based industrial or academic experience and/or training • Previous exposure to in vitro electrophysiology (high throughput platforms and/or ussings would be preferred) Additional Information For more information, please contact Sneha Shrivastava ************

Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost. Job Description: There is an immediate opening for an experienced, highly-motivated and energetic Scientist to join the Integrated Biologics Profiling (IBP) group. IBP is a Development unit that works with various Research teams to express, purify, and characterize monoclonal antibodies and other therapeutic proteins, and help select the best drug candidates with suitable manufacturability properties. The selected candidate will work in a team responsible for the physicochemical and biophysical characterization of protein therapeutics, in particular monoclonal antibodies. Duties and Responsibilities: Execute analytical work including standard protein HPLC (size exclusion, reverse phase, ion exchange, affinity), and electrophoretic analyses (CZE, cIEF, CE-SDS) Support sample and buffer preparation for formulation and analytical characterization studies Work in a highly interdisciplinary and collaborative environment as part of the IBP team. Perform work semi-independently under mentorship of a functional lead. Able to multi-task to support several project proteins and able to manage accelerated timelines. Accurate and timely process data and documentation, Maintain analytical equipment and support other lab organization tasks Qualifications Skills: Hands-on experience in physicochemical protein analytics, with emphasis on standard HPLC and electrophoretic methods for identification and characterization of therapeutic proteins Highly self-motivated, organized and self-driven team player, with great interpersonal skills and excellent oral and written communication capabilities. Education: Candidate should have a B.S. degree in Biochemistry, Analytical Chemistry, or a similar life science field with a minimum of 2 years of experience in protein Additional Information Best Regards, Anuj Mehta **********

Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost. Job Description SPR Scientist with biosensor and/or automated liquid handling experience characterizing biotherapeutic candidates. The qualified candidate will use an automated liquid handler to prepare samples and conduct experiments with a variety of biosensor instruments. The candidate will work closely with the SPR group lead to establish priorities and further develop automation capabilities. The candidate should be eager to meet aggressive timelines, multi-task experiments, and advance biotherapeutic discovery. Required Skills: 1. Liquid Handling 2. Assays Additional Information Best Regards, Anuj Mehta ************

Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost. Job Description The Respiratory Science group is looking for a highly motivated associate scientist with experience in electrophysiology to be part of a team committed to finding treatments for cystic fibrosis, COPD and other respiratory diseases. The successful candidate will be primarily responsible for primary cell culture (experience with aseptic technique is required), developing and conducting in vitro electrophysiological assays focused on ion transport and its roles in the airway. You will also be involved in new drug target identification and validation as well as investigating the mechanism of action of potential drug candidates. We are looking for a candidate who can utilize their strong technical and organizational skills and has an enthusiastic, collaborative spirit. Additional responsibilities include: 1) Manage laboratory resources, i.e. reagents and supplies, performing routine maintenance and calibration etc. 2) Analyze, interpret and present your results, participate in meetings with team members and other research staff to evaluate, interpret and quality-control the data you generate as well as to identify next steps 3) Learn new techniques and approaches as required to tackle key scientific questions. 4) Recognize and troubleshoot data anomalies to maintain high data quality Minimum requirements: • Bachelors or Master's degree in Biology, Biophysics or related discipline • A minimum of two years of laboratory-based industrial or academic experience and/or training • Previous exposure to in vitro electrophysiology (high throughput platforms and/or ussings would be preferred) • Experience working with human primary cell cultures and other cell lines • Self-motivated and pro-active attitude, with the ability to multi-task • Solid work ethic and demonstrated record of productivity and high quality data • Intermediate/advanced ability with MS Office, especially Excel, and ability to learn new software • Excellent problem solving, organizational and experimental management skills • Strong written and verbal communication skills • Commitment to help the team achieve deliverables and meet aggressive timelines • Ability to be both independent as well as effectively interact with team members and work in a highly dynamic and collaborative environment Additional, highly desirable qualifications: • Experience with cell-based high throughput screening assays • Familiarity with basic statistical analyses and how to apply them to biological data • Flexibility and willingness to occasionally adjust your hours as required by specific experiments Qualifications Minimum requirements: • Bachelors or Master's degree in Biology, Biophysics or related discipline • A minimum of two years of laboratory-based industrial or academic experience and/or training • Previous exposure to in vitro electrophysiology (high throughput platforms and/or ussings would be preferred) Additional Information For more information, please contact Sneha Shrivastava ************

We are reputed staffing agency, founded in 1999, Mindlance is a certified diversity business (MBE) and has been ranked one of the fastest growing U.S staffing firms by SIA for eight consecutive years. Title: Associate Scientist Duration: 12 months Location: Cambridge, MA Job Description The Gene Therapy Accelerator Unit (GTxAU) at *** is seeking a committed, enthusiastic, and dependable scientist to contribute to the generation of gene therapy laboratory and clinical candidates for neurodegenerative and neuroinflammatory diseases. The Associate Scientist II/III, cargo engineering, will work collaboratively with a cross-function team and growth potentials. The incumbent will be part of a team focused on cargo/AAV vector designing and characterization for in vitro and in vivo testing. An ideal candidate will have experience in mammalian cell culture, cell line engineering, molecular biology techniques, and biochemical/immunological assays. This candidate should be able to design, execute, and analyze in vitro experiments independently with strong scientific rigor. The ideal candidate should also maintain an up-to-date knowledge of pertinent literature and possess excellent communication and interpersonal skills to efficiently present results to project team members. • AAV vector designing by adapting existing protocols, including titering assay by dd PCR, genome integrity assay, empty/full particle ratio assay, endotoxin assay, residual DNA and protein assays • Maintain constant awareness of Client biochemical and biophysical technologies for AAV purification and characterization • Work as a liaison between GTxAU and the upstream and downstream process teams • Establish SOPs and adapt new protocols from literature • Manage external CROs for plasmid or vector production • Maintain electronic laboratory notebooks, present data to the team, and write study reports Qualifications Qualifications • 2+ years of experience in biotech/pharmaceutical industry or academic setting • Experience with mammalian cell culture and cell line engineering • Hands-on experience with molecular biology techniques (cloning, qPCR, dd PCR, DNA gel electrophoresis, SDS-PAGE, WB, ELISA, etc.) • Ability to independently design, execute, and analyze in vitro molecular biology experiments • Critical thinking and presentation skills a must • Strong communication and organizational skills • Ability to productively collaborate in cross-function teams Preferred: • Hands-on experience with AAV and/or other gene therapy delivery systems • Hands-on experience with immunological assays • Previous research experience in neuroscience/neurological disorders Education: • BS or MS in scientific field (biology, biochemistry, biotechnology, etc.) Additional Information All your information will be kept confidential according to EEO guidelines.

Top 3 Must Have Skill Sets: Synthetic organic chemistry or Medicinal chemistry Chromatographic purification Knowledge and experience with chemical structure determination Day to Day Responsibilities: • Work in teams to develop, implement and perform organic reactions for ongoing Medicinal Chemistry teams • Troubleshoot synthetic routes and reactions, and scout new synthetic routes. • Perform structural determinations using NMR and Mass Spectral techniques • Purify compounds using chromatographic and other techniques and submit purified compounds to biological testing • Carry out all laboratory work in accordance with safe practices and comply with all relevant regulations and procedures • Maintain laboratory notebooks • Participate in group and project meetings • Present results to groups • Aid in the writing of papers and patent applications This individual will be part of a Medicinal Chemistry group, with responsibilities including (but not limited to) the synthesis and purification of novel compounds for potential clinical drug development. Basic qualifications: • Master's degree & 2 years of synthetic organic chemistry experience OR • Bachelor's degree & 4 years of synthetic organic chemistry experience Preferred Qualifications •Focus or specialization in synthetic organic or medicinal chemistry •Demonstrated ability to scout and troubleshoot synthetic routes •Clear understanding of structural determination using NMR and Mass Spectral techniques as well as knowledge of purification methods •Demonstration of good lab practices, with particular attention to safety •Excellent communication skills (both written and oral) and the ability to work well in teams Qualifications Basic qualifications: • Master's degree & 2 years of synthetic organic chemistry experience OR • Bachelor's degree & 4 years of synthetic organic chemistry experience Preferred Qualifications •Focus or specialization in synthetic organic or medicinal chemistry •Demonstrated ability to scout and troubleshoot synthetic routes •Clear understanding of structural determination using NMR and Mass Spectral techniques as well as knowledge of purification methods •Demonstration of good lab practices, with particular attention to safety

Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost. Job Description • The candidate will be part of a group responsible for developing analytical methodologies and strategies needed to progress biotherapeutic products through the pipeline; this includes method development and qualification, process support, formulation and stability support, and product characterization. • The candidate will be responsible for becoming proficient in a number of analytical methodologies including HPLC, SDS-PAGE, iCE, CE, UV-Vis, and a variety of compendial assays. The main function of the position will be to provide routine analytical testing using established methodologies. • The ideal candidate will have experience using some or all of the above analytical methodologies for the analysis of biologics (e.g. proteins, antibodies, peptides, and conjugates), and have proficiency in Microsoft Office software such as Excel and Powerpoint. • Other experiences of interest include familiarization with cGMPs, working knowledge of various data systems including Waters Empower . • Required skills are HPLC and/or CGE (aka SDS-CE). Empower experience is highly desirable. • In addition, the candidate should have good documentation skills and will be expected to tabulate and provide data interpretation to their team and to their customers. • The candidate must excel at working in a collaborative, fast-paced environment. Qualifications BS or MS in Science field Additional Information Best Regards, Anuj Mehta ************

At the dawn of the new millennium, a unique information technology company was born: HCL Technologies. As narrated in the video below, HCL Technologies has demonstrated remarkable growth through the recent economic downturn, emerging as one of only eight 21st century listed technology companies in the world to cross $1bn in Net Profit, $6bn in Revenue and $15bn in Market Capitalization. Job Description REQUIRED SKILLS • BS/MS in molecular biology or related field • 1+ year of laboratory experience • gDNA/RNA preparation • northern/southern blot analysis. • Molecular biologist to aid in characterization of recombinant mammalian cell lines. Requires BS/MS in molecular biology or related field and at least one year of laboratory experience. • Must be familiar with general cell culture techniques (ex. aseptic passaging of cell lines), RNA, cDNA and genomic DNA preparation, DNA/RNA quantitation like dd PCRor taqman, and Southern analyses. • Experience with molecular cloning techniques such as plasmid construction using Gibson assembly, DNA sequencing technologies and analysis of DNA sequencing data are strongly desired. REQUIRED PERSONALITY TRAITS: • Team oriented, fast learner, good attention. • Responsible for general laboratory and operational support. Including providing logistical support for samples and compounds management, ordering supplies and carrying out general bench work activities. Additional Information Best Regards, Anuj Mehta ************ Morristown, NJ 07960

Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost. Job Description • A position is available in the Mass Spectrometry and Biophysical Characterization group in Analytical R&D. • The qualified candidate will be responsible for developing and implementing methods of analysis for the characterization of proteins and peptides using advanced analytical techniques. • The qualifications include a minimum of a B.S. in chemistry, biochemistry, biology, or related field; industrial experience in analytical characterization is desirable. • The qualified colleague must have knowledge in protein biochemistry and/or protein analytics, and should have expertise in one or more protein characterization tools, including mass spectrometry, chromatographic separations, or proteolytic mapping. These techniques will be applied to a large platform of projects in all stages of development. • Attention to detail, focused, team oriented, independent, and good communication and writing skills are essential due to the highly matrixed, fast-paced, project-team environment. Proficient in Microsoft PowerPoint, Excel, and Word. Qualifications The qualifications include a minimum of a B.S. in chemistry, biochemistry, biology, or related field; industrial experience in analytical characterization is desirable. Additional Information Sneha Shrivastava Technical Recruiter (Clinical/Scientific) Artech Information Systems LLC 360 Mt. Kemble Avenue, Suite 2000 | Morristown, NJ 07960 Office: ************ | Fax: ************ Connect with us on - LinkedIn | Facebook | Twitter

Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost. Job Description • Hands-on experiences with HPLC, UPLC, LC/MS, LC/MS/MS, SFC, Ion Chromatography, CE, GC, GC/MS, GC/MS/MS; • Working knowledge in organic synthesis /small molecule purification; chiral purification experience is a plus; • Extensive experience in method development, basic instrument maintenance and troubleshooting; • Must be an effective communicator with excellent interpersonal, organizational and problem solving skills, cooperative and flexible; • Ability to manage multiple tasks, and perform well under pressure and stringent deadlines Qualifications MS degree in chemistry with a minimum of five years of relevant experience or PhD degree in chemistry with a minimum of two years of relevant experience; Working experience in pharmaceutical industry (small molecule); Working knowledge in LIMS, research database and eNotebook; Broad knowledge in the application of analytical chemistry in pharmaceutical discovery research Additional Information Warm Regards Anuj Mehta Technical Recruiter Artech Information Systems LLC 360 Mt. Kemble Avenue, Suite 2000 | Morristown, NJ 07960 Office: ************ Ext : 3204 | Fax: ************

US Tech Solutions is a global staff augmentation firm providing a wide-range of talent on-demand and total workforce solutions. To know more about US Tech Solutions, please visit our website ************************ We are constantly on the lookout for professionals to fulfill the staffing needs of our clients, sets the correct expectation and thus becomes an accelerator in the mutual growth of the individual and the organization as well. Keeping the same intent in mind, we would like you to consider the job opening with US Tech Solutions that fits your expertise and skillset. Job Description The qualified candidate will join the Analytical R&D organization located in Andover, MA to enable the development of biological therapeutics at Pfizer Worldwide Research and Development. The candidate will be part of a group responsible for developing analytical methodologies and strategies needed to progress biotherapeutic products through the pipeline; this includes method development and qualification, process support, formulation and stability support, and product characterization. The candidate will be responsible for becoming proficient in a number of analytical methodologies including HPLC, SDS-PAGE, iCE, CE, UV-Vis, and a variety of compendial assays. The main function of the position will be to provide routine analytical testing using established methodologies. The ideal candidate will have experience using some or all of the above analytical methodologies for the analysis of biologics (e.g. proteins, antibodies, peptides, and conjugates), and have proficiency in Microsoft Office software such as Excel and Powerpoint. Other experiences of interest include familiarization with cGMPs, working knowledge of various data systems including Waters Empower . Required skills are HPLC and/or CGE (aka SDS-CE). Empower experience is highly desirable. In addition, the candidate should have good documentation skills and will be expected to tabulate and provide data interpretation to their team and to their customers. The candidate must excel at working in a collaborative, fast-paced environment Qualifications Bachelors Additional Information Sneha Shrivastava Sr Technical Recruiter ********************************* 862 - 579 - 4236

US Tech Solutions is a global staff augmentation firm providing a wide-range of talent on-demand and total workforce solutions. To know more about US Tech Solutions, please visit our website ************************ We are constantly on the lookout for professionals to fulfill the staffing needs of our clients, sets the correct expectation and thus becomes an accelerator in the mutual growth of the individual and the organization as well. Keeping the same intent in mind, we would like you to consider the job opening with US Tech Solutions that fits your expertise and skillset. Job Description The qualified candidate will join the Analytical R&D organization located in Andover, MA to enable the development of biological therapeutics at Pfizer Worldwide Research and Development. The candidate will be part of a group responsible for developing analytical methodologies and strategies needed to progress biotherapeutic products through the pipeline; this includes method development and qualification, process support, formulation and stability support, and product characterization. The candidate will be responsible for becoming proficient in a number of analytical methodologies including HPLC, SDS-PAGE, iCE, CE, UV-Vis, and a variety of compendial assays. The main function of the position will be to provide routine analytical testing using established methodologies. The ideal candidate will have experience using some or all of the above analytical methodologies for the analysis of biologics (e.g. proteins, antibodies, peptides, and conjugates), and have proficiency in Microsoft Office software such as Excel and Powerpoint. Other experiences of interest include familiarization with cGMPs, working knowledge of various data systems including Waters Empower . Required skills are HPLC and/or CGE (aka SDS-CE). Empower experience is highly desirable. In addition, the candidate should have good documentation skills and will be expected to tabulate and provide data interpretation to their team and to their customers. The candidate must excel at working in a collaborative, fast-paced environment Qualifications Bachelors Additional Information Sneha Shrivastava Sr Technical Recruiter ********************************* 862 - 579 - 4236

Our start-up is building a novel chemical discovery platform to reshape how we develop formulations at the molecular level. By combining artificial intelligence with a cutting-edge laboratory discovery pipeline, our interdisciplinary team will chart an unexplored chemical landscape, enabling breakthroughs in drug delivery, agrichemical formulation, and safe, high-performance industrial chemicals. Our company is backed by Flagship Pioneering, a biotechnology origination company that has founded and developed over 115 scientific ventures over the past 25 years. Flagship Pioneering is dedicated to the development of an ecosystem of first-in-category life sciences companies, resulting in $20+ billion in aggregate value, 500+ issued patents, and more than 50 clinical trials for novel therapeutic agents. THE ROLE We are seeking an experienced formulations chemist to lead the design, strategy, and implementation of a high-throughput chemical formulation and testing pipeline. This position will focus on building a rapid and evolving system for manufacturing chemical mixtures and measuring the physiochemical properties of these mixtures at various temperatures and levels of hydration. This position will also coordinate heavily with a Machine Learning Lead to integrate the bench top pipeline output with the training and output of a predictive model for formulation chemistry. The ideal candidate will have a strong background in organic chemistry, high-throughput chemical screening, spectroscopy, calorimetry, and other advanced techniques for the physical characterization of chemicals. KEY RESPONSIBILITIES Manufacturing formulations Design and implement a scalable high-throughput workflow for generating diverse chemical mixtures. Rigorously catalog known formulations for comparison to newly developed and untested formulations. Establish automated liquid handling, dosing, and mixing protocols to ensure reproducibility and throughput. Develop standard operating procedures (SOPs) for safe handling, storage, and disposal of raw materials and formulations. Collaborate with upstream ML lead on formulation design workflows that maximize our canvassing of chemical property space and support the generation of high-quality, broad-coverage training data. Characterizing formulation properties Assess viscosity, solubility, and other physiochemical features under different hydration and temperature conditions. Apply spectroscopy (UV-Vis, IR, fluorescence) to quantify molecular interactions and stability. Use calorimetry and thermal gravimetric analysis to measure thermodynamic and thermal stability profiles of formulations. Develop and validate assays to track long-term stability and degradation of formulations. Screening formulation-cargo interactions Design assays to evaluate compatibility of formulations with diverse small molecules, peptides, proteins, and nucleic acids. Measure cargo protection and stability (e.g., aggregation, precipitation, degradation) under varied conditions. Integrate biophysical characterization methods (DLS, CD, IR, LCMS) to assess cargo-formulation interactions. PROFESSIONAL EXPERIENCE & QUALIFICATIONS Ph.D. in Organic Chemistry, Physical Chemistry, Chemical Engineering, Materials Science, or a related field + 5 years of experience (including 2 years of industry at minimum). Extensive hands-on experience with formulation chemistry, high-throughput chemical screening, or analytical method development. Demonstrated expertise in chemical characterization techniques such as spectroscopy (UV-Vis, IR, NMR, fluorescence), calorimetry (DSC, ITC), and rheology. Proven ability to characterize physicochemical properties of complex mixtures under varying environmental conditions. Strong background in designing and executing high-throughput or automated experimental workflows. Committed team player with the ability to communicate and work collaboratively with ML scientists, lab scientists and operational team members. Prior leadership or team management experience preferred. Experience integrating benchtop experimental data into machine learning pipelines or predictive modeling workflows preferred. Strong understanding of thermodynamics, kinetics, and intermolecular interactions in multicomponent systems preferred. Familiarity with high-throughput robotics, automation platforms, or liquid handling systems for screening of solvents and liquids preferred. Knowledge of data analysis pipelines, including scripting skills (e.g., Python, R, MATLAB) for handling large experimental datasets preferred. Exposure to generative AI models for chemical discovery preferred. Experience working with biomolecules and protein chemistry preferred. Familiarity with principles of physical chemistry preferred. Experience in chemistry screening for personal care, nutrition, or aqueous coatings and adhesives preferred. LOCATION: Cambridge, MA ABOUT FLAGSHIP PIONEERING: Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity's most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE's “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company's annual list of the World's Most Innovative Companies. Learn more about Flagship at *************************** At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact. We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship. Recruitment & Staffing Agencies : Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto. #LI-TL1 The salary range for this role is $126,000 - $181,500. Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. FL118 currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on FL118's good faith estimate as of the date of publication and may be modified in the future.

Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost. • The purpose of this position is to provide support in evaluating various rodent genetic backgrounds in eliciting robust immune response within GBT. • By performing phenotypic analysis of B cell compartment, deep sequencing of B cell repertoire, and studying antibody responses from immunized rodents, we will be able to understand the utility of these animals in biotherapeutic development. • The incumbent, under the supervision by Pharmaceutical scientist, will be involved in the evaluation of the animals through the use of various immunogens, immunization approaches, and characterization method Specific job description: • Perform phenotypic analysis of lymphocyte compartments of rodents • Perform deep sequencing of B cell repertoire of animals and analyze repertoire diversity pre and post immunization • Immunize rodents using various strategies • Characterize antibodies diversity post immunization • Clone and express desired monoclonal antibodies for further analysis Experience: • Knowledge and work experience in the B cell phenotypic analysis by Flow Cytometry • Knowledge and work experience in hybridoma generation • Knowledge and work experience in rodent primary B cell culture • Knowledge and work experience in Ig cloning from B cell • Knowledge and work experience in affinity purification of polyclonal antibodies • Knowledge and work experience in screening and functional assay development for selecting specific monoclonal antibodies • Work experience in NGS of Ig repertoire • Relevant industrial experience is preferred Specific work plan: a) Perform all aspects of phenotypic analysis of lymphocyte compartments of rodents b) Perform, design and analyze B cell repertoire of rodents by deep sequencing c) Perform and design immunization strategies and generate hybridoma d) Evaluate and characterize immune response and monoclonal antibodies from desired rodents e) Contribute to drafting relevant documentation such as immunization protocols, phenotypic and repertoire analysis reports and laboratory methods. Qualifications Bachelor's degree required Additional Information Best Regards, Anuj Mehta ************

A Few Words About Us Integrated Resources, Inc is a premier staffing firm recognized as one of the tri-states most well-respected professional specialty firms. IRI has built its reputation on excellent service and integrity since its inception in 1996. Our mission centers on delivering only the best quality talent, the first time and every time. We provide quality resources in four specialty areas: Information Technology (IT), Clinical Research, Rehabilitation Therapy and Nursing. With todays growing demand for talented and well qualified professionals, its more important than ever to partner with a company that employs innovative measures to meet your demands. Our expert team of highly trained counselors work hand in hand with every client forming a partnership of understanding and commitment. Our clients know that they can rely on us for prompt response times and reliable staff to meet their workforce demands. Our employees know that they can trust our support for their career development and personal growth. IRI is proud to be JCAHO Certified by the Joint Commissions of Health, MBE Certified by the State of NJ and the National Minority Supplier Diversity Council (NMSDC) and SBE Certified by the State of NJ. We have been honored by the following: Top 100 Diversity Owned Business in NJ for 2007, 2008 and 2009 Top 500 Privately-Held Business in the US Top 500 Diversity Owned Business in the US Top 100 Subcontinent Asian American Business in the US We have also been listed to the Inc. 5000 List of fastest-growing, privately-held companies in the US in 2007, 2008, 2009 and 2010 and honored as an Emerging Business of the Year finalist by NJ BIZ in 2009. Job Description Location- Lexington, MA Duration- 9m +++ Development Engineer / Associate (Contract) - Clinical Drug Product Manufacturing Sciences (CDPMS) The Development Engineer / Associate - CDPMS will assist drug product tech transfer teams with project management support. Project management support will include scheduling, resource planning, and project task tracking. A candidate with the right experience would have the opportunity to lead a drug product tech transfer team. The primary responsibility of the candidate will be to perform project management activities to manage the external manufacture of clinical trial materials. In addition, the candidate will coordinate external research projects such as compatibility and filter validation studies. Additional responsibilities will include performing drug product process development studies in collaboration with drug product manufacturing and formulation development teams. The Development Engineer / Associate will also analyze experimental data, document results and conclusions in technical reports, and assist Senior Staff with drug product tech transfer management projects. This will be a visible and hands on role with opportunities to contribute to multiple clinical stage programs. In this role, the Development Engineer / Associate must be able to work independently and be self-motivated. The candidate must manage time efficiently to balance multiple projects and priorities. Excellent organization and communication (oral and written) skills are required. Qualifications Qualifications • BS/MS in degree in chemical, biochemical, biomedical engineering, chemistry or related field • 3-6 years industry experience in formulation and/or drug product process development • Experience in supporting tech transfer projects to contract research and/or manufacturing organizations • Project management experience including time and resource scheduling • Experience in a GMP environment or GLP laboratory is preferred • Experience with Microsoft Project, Vizio, and advanced Excel spreadsheets is preferred • Experience managing outsourced research projects is a plus • Knowledge of statistical design of experiments is a plus Additional Information All your information will be kept confidential according to EEO guidelines.