Senior Associate Scientist jobs at Amgen

Additional Information About the Role A research scientist is a doctoral prepared clinician that educates, mentors and consults for healthcare professionals, as well as conducts projects across the trajectory of scholarly work (PI, QI, EBP and Research) to improve patient outcomes and experience. The research scientist provides guidance and assistance for dissemination of scholarly work. PhD in Nursing required, or DNS. Active MO RN License Required Position is based onsite at Barnes Jewish Hospital Supports Magnet facilty Overview Preferred Qualifications Role Purpose Develops the health services research program. Facilitates and independently conducts academic/clinical research, supports research utilization in nursing/clinical practice and develops an ongoing strategic plan for academic/clinical research. Responsibilities Conducts interdisciplinary research and evidence-based practice projects that support the organization's priorities for improving patient and/or care delivery outcomes. Serves in a consultative role for patient care services staff in the development and completion of interdisciplinary research and evidence based practice projects and scholarly activities. Collaborates with patient care services clinicians, including physician partners, to evaluate and implement best practices for clinical care, patient care delivery models, education and use of technology. Mentors nursing and allied health professionals in developing presentations, posters and written articles or abstracts. Presents original research and evidence based practice at regional and national conferences with poster or podium presentations and submits for publication in peer-review journals. Minimum Requirements Education Doctorate - Nursing/Healthcare related Experience 5-10 years Supervisor Experience No Experience Licenses & Certifications Cert/Lic in Area of Expertise Benefits and Legal Statement BJC Total Rewards At BJC we're committed to providing you and your family with benefits and resources to help you manage your physical, emotional, social and financial well-being. Comprehensive medical, dental, vison, life insurance, and legal services available first day of the month after hire date Disability insurance* paid for by BJC Annual 4% BJC Automatic Retirement Contribution 401(k) plan with BJC match Tuition Assistance available on first day BJC Institute for Learning and Development Health Care and Dependent Care Flexible Spending Accounts Paid Time Off benefit combines vacation, sick days, holidays and personal time Adoption assistance To learn more, go to our Benefits Summary *Not all benefits apply to all jobs The above information on this description has been designed to indicate the general nature and level of work performed by employees in this position. It is not designed to contain or be interpreted as an exhaustive list of all responsibilities, duties and qualifications required of employees assigned to this job. Equal Opportunity Employer

6 month contract w/ renewal 3 days onsite in Jersey City, NJ We are seeking a Clinical Scientist Data Reviewer that will support the scientific planning efforts and collaborate with Clinical Research, Pharmacovigilance and Clinical Operations in the execution of one or more clinical trials or significant aspects thereof. In this position, you will have the opportunity to demonstrate technical skills and scientific acumen as part of a cross-functional clinical development team. You will be a key contributor and supporter in the clinical science activities of evidence generation for regulatory approval and/or engagement with physicians, including protocol development, study implementation, data analysis and reporting of results. This role will be focused on the detailed and critical safety data review efforts from study start-up through final CSR. The Clinical Scientist Data Reviewer is a crucial role in analyzing and interpreting clinical trial data to ensure accuracy, integrity, and compliance with regulatory requirements. There is additional room for growth and leadership opportunities in this role. Responsible for supporting specific aspects of clinical/scientific execution of clinical protocol(s). This may include: Serving as a supportive clinical scientist data reviewer focused on safety, efficacy and critical data deliveries as part of the clinical trial team Supporting the clinical study team as part of the clinical sciences functional line which is closely aligned with the medical monitoring team in review and interpretation of clinical data/medical protocol deviations in collaboration with Clinical Research and Pharmacovigilance (as well as other functional areas in this matrix environment) Collaborating cross-functionally in the development of Protocol and related study materials (e.g., ICF documents / amendments); partnering with Clinical Operations on critical and key study deliverables Ensure CRF design supports data collection in alignment with the Protocol in collaboration with Clinical Data Management/Programming Collaborating cross-functionally to review clinical data to ensure quality, completeness, and integrity of trial conduct Potential to provide tactical/scientific mentorship to other clinical scientists and move into Clinical Scientist lead role as well as focus on scientific growth and development Responsible for assisting with the generation, analysis, and presentation of clinical data, including manuscripts, abstracts, and oral presentations (including authoring documents and slide preparation as appropriate) Apply proficient analytical knowledge and skills to understand how program objectives and design impact data analysis; identifies risks and designs mitigation strategies Promotes consistent first line medical/clinical data review techniques and conventions across studies/programs Qualifications 6+ years of experience with a Post Graduate Degree or 8+ years of experience with a Bachelor's degree in a relevant scientific discipline. Experience in clinical drug development experience, or a PhD, Pharm D, or RN degree is preferred. Experience within oncology preferred Solid knowledge of clinical research regulatory requirements (e.g., GCP and ICH) Ability to manage multiple competing priorities with good planning, time management and prioritization skills Strong analytical skills with the ability to interpret clinical trial data and synthesize conclusions Proficient scientific expertise to propose, design, and execute clinical research and development studies, and authors documents related to clinical trials, such as medical monitoring plan, SAPs, informed consent and clinical components of the Clinical Study Reports Interact with key stakeholders across Clinical Development functional areas Role requires proactive approach, strategic thinking and leadership in driving toward clinical study goals Influence opinions and decisions of internal and external customers / vendors, across functional areas Problem solving, prioritization, conflict resolution and critical thinking skills Strong communication, technical writing, and presentation skills experience

St. Luke's University Health Network, the region's largest, most established health system, a major teaching hospital, and one of the nation's 100 Top Hospitals is seeking a Medical Toxicology BC/BE physician to join our dedicated team of physicians providing excellent care throughout our network. Background in Emergency Medicine and/or Addiction Medicine are a plus. In joining the current team of Medical Toxicologists you'll participate in providing: Expert medical toxicology bedside and telemedicine consultation at a large hospital network Consultation management of patients suffering acute alcohol, benzodiazepine, and opioid withdrawal with coexisting medical illnesses or complications. Outpatient care in a brand-new outpatient addiction medicine clinic Education to rotating residents, fellows, and medical students In joining St. Luke's University Health Network you'll enjoy Rich benefits package, including malpractice, health and dental insurance, CME allowance $25k starting bonus Team-based care with well-educated, dedicated support staff A culture in which innovation is highly valued Professional support and growth within the network Teaching, research, quality improvement and strategic development opportunities Qualifications: Medical degree - DO or MD Completion of an accredited Emergency Medicine residency program preferable but not required Board certification/eligibility in Emergency Medicine or your primary specialty Completion of Medical Toxicology fellowship Board certification/eligibility in Medical Toxicology Addiction Medicine experience or BC/BE is a plus.

Senior Manager, MED RWE/Epi Scientist The Senior Manager, RWE/Epi Scientist, position within Medical Evidence Development (MED) Real-World Evidence & Epidemiology (RWE/Epi) provides an opportunity for a collaborative epidemiologist to support real-world evidence and epidemiologic studies as part of Medical strategy across the entire drug development process. The candidate will be responsible for synthesizing the literature and contributing to the design, conduct and reporting of global epidemiologic research studies on Pfizer I&I products. The Senior Manager will also be accountable for the quality, timeliness, and efficiency of all RWE/Epi deliverables in assigned product/disease area, and maintain an internal network of Pfizer stakeholders to cultivate innovation, cross-functional collaboration, and identify new opportunities for RWE/Epito increase the value of Pfizer assets. The candidate will develop external partnerships to leverage data resources and collaboration on high priority global studies. Responsibilities include authoring and reviewing study protocols, reports, and presentations, as well as communication in writing and presentations to internal stakeholders, regulatory authorities, and medical professionals. The candidate will also be responsible for non-study deliverables such as RWE insights, epidemiology literature reviews, regulatory responses, and department initiatives. This position will report directly to the Hem-Onc Team Lead in RWE/Epi. Capabilities Skill and experience identifying, designing and supporting or leading real-world evidence studies of disease epidemiology and effectiveness as part of the global cross-functional Integrated Evidence Plan. Maintain knowledge and awareness of internal and external data resources and identify appropriate studies for addressing questions of interest, recognizing the limitations and strengths of various design options and data sources Partner with Chief Medical Office colleagues to address asset team evidence needs and support global regulatory submissions to the FDA, EMA and other agencies. Deliver rapid insights from real-world, observational data source Develop and deliver presentations, webinars, manuscripts, scientific data packages or other communication modalities Assure the highest standards of quality, compliance and management of all research activities Participate in RWE/Epi peer review of study protocols and study reports Document all requests and track progress toward project completion, other metrics and business goals Qualifications PhD in Epidemiology, Statistics/Biostatistics, Health Outcomes Research, Quantitative Methods, Public Health, Health Economics, or Other Biological Science fields with a substantial quantitative component and at least 1 years of relevant experience in the pharmaceutical, academic and/or medical environment; or, MPH or another relevant Master's degree and at least 5 years of experience in the pharmaceutical, academic and/or medical environment, at least 1 of which were in the pharmaceutical industry. Demonstrated strong quantitative skills and methods expertise to generate rapid insights from real-world / observational data source Demonstrated strong technical writing skills and oral presentation skills with a track-record of publishing in peer-reviewed journals and presenting at medical/scientific conferences Demonstrated ability to convert complex analysis into meaningful insights with data visualization and presentation tools and able to manipulate and analyze complex structured and unstructured data from multiple real world evidence sources. Ability to work under pressure with a high level of autonomy/leadership on research projects and collaborate with multiple partners in a matrixed environment Knowledgeable of the external regulatory environment for real-world evidence and maintains awareness of scientific developments in epidemiology, medicine, and technology (e.g., artificial intelligence). Bonus Points If You Have (Preferred Requirements): Proficiency in rapid real-world data analytical platforms Experience working with real-world data (RWD) including Electronic Medical Records (EMR), claims, and surveys Excellent problem-solving and decision-making abilities Ability to influence and collaborate with senior management and stakeholders Strong project management skills with the ability to handle multiple projects simultaneously Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact. PHYSICAL/MENTAL REQUIREMENTS Lifting, sitting, standing, walking, bending, ability to perform mathematical calculations and ability to perform complex data analysis. Work Location Assignment: This is a hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week or more as needed. OTHER JOB DETAILS Last Date to Apply for Job: December 29, 2025 Eligible for Relocation Package: No The annual base salary for this position ranges from $135,100.00 to $225,100.00.* In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.* The annual base salary for this position in Tampa, FL ranges from $121,600.00 to $202,600.00. Relocation assistance may be available based on business needs and/or eligibility. Sunshine Act Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative. EEO & Employment Eligibility Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States. Pfizer endeavors to make ********************** accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email ...@pfizer.com. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned. Medical

Site: Mass General Brigham Incorporated Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. Job Summary Summary Drives the application of clinical bioinformatics and other clinical/research/education informatics needs in the department through software engineering. Essential Functions * Manage multiple bioinformatics coding tasks and projects at the same time. * Design and develop software solutions that meet product requirements. * Collaborate with product managers and stakeholders to gather and refine software requirements. * Implement and maintain software features and improvements. * Conduct thorough testing and debugging to ensure the quality and reliability of the software. * Help train other engineers and provide technical guidance. * Improve the current pipeline automation by developing the feature requests and enhancements from the end users. Qualifications Education Bachelor's Degree Bioinformatics required or Bachelor's Degree Related Field of Study required or Master's Degree Bioinformatics preferred Can this role accept experience in lieu of a degree? Yes Licenses and Credentials Experience Experience in bioinformatics engineering or related software engineering 3-5 years required Knowledge, Skills and Abilities * Strong understanding of software design patterns and principles. * Familiarity with version control systems and agile development methodologies. * Back-end and API development abilities using programs such as Python, NodeJS, C#, Java, R, and Perl. * Solid SQL proficiency. * Strong familiarity with SDLC principles. * Strong interpersonal skills and ability to effectively interact with all levels of staff and external contacts. Additional Job Details (if applicable) * M-F Eastern Business Hours required * Hybrid Onsite Flexible working model required weekly includes onsite in office (1-2 days per week weekly, must be flexible for business needs) * Remote working days require stable, secure, quiet, compliant working station Remote Type Hybrid Work Location 399 Revolution Drive Scheduled Weekly Hours 40 Employee Type Regular Work Shift Day (United States of America) Pay Range $92,102.40 - $134,056.00/Annual Grade 7 At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package. EEO Statement: Mass General Brigham Incorporated is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at **************. Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership "looks like" by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.

Are you looking for an opportunity to make a difference? At Mesa Labs we're passionate about protecting the vulnerable by enabling scientific breakthroughs, ensuring product integrity, increasing patient and worker safety, and improving quality of life around the world. At Mesa Labs we offer competitive wages, including bonus opportunity, and a comprehensive benefits package. Base Compensation Range: $27.04/ hour - $33.77/ hour This position is eligible for an annual 10% bonus opportunity in addition to the base salary Outstanding Benefits and Perks: We are proud to offer a variety of benefits that meet the diverse needs of our employees: * Eligible for benefits the first day of the month after you start * Tiered Medical, Dental and Vision Insurance options * Health savings (HSA), healthcare & dependent care flexible spending (FSA) accounts * Company paid short term and long-term disability (unless covered by a state disability plan) * Company paid life insurance and AD&D * 3 weeks of accrued vacation time; accruals begin on Day 1 * Paid sick leave of 48 hours per calendar year * Eligible employees may receive four (4) weeks paid Care Giver leave after 1 year of service or in accordance with state leave laws * 401(k) plan that provides a 4% Safe Harbor company match on a 4% employee contribution that begins on Day 1 * Employee Wellness and Financial Assistance Resources through Cigna and NY Life * Nine (9) paid company holidays per year * Overtime opportunities This position supports Mesa's SDC business. Our Sterilization and Disinfection Control division manufactures and sells biological and chemical indicators that assess the effectiveness of sterilization and disinfection processes for pharmaceutical, healthcare, and dental industries. Job Summary The Associate Scientist in R&D will contribute to the design, execution, and analysis of science based projects aimed at advancing product development initiatives. This role requires a strong foundation in scientific principles, hands-on laboratory experience, and the ability to work collaboratively within a multidisciplinary team. Duties/Responsibilities Experimental Design and Execution: * Develop and execute experiments to support product development and improvement. * Design protocols and methodologies to test hypotheses and analyze results. Data Collection and Analysis: * Collect, record, and analyze experimental data using appropriate statistical methods. * Interpret results and prepare reports summarizing findings and recommendations. Documentation and Compliance: * Maintain accurate and detailed laboratory notebooks in compliance with Good Laboratory Practices (GLP). * Ensure all research activities adhere to relevant safety and regulatory guidelines. Collaboration and Communication: * Collaborate with cross-functional teams, including Product Development, Quality Assurance, and Regulatory Affairs. * Present research findings in team meetings and contribute to project planning discussions. Literature Review and Research: * Conduct literature reviews to stay informed about current trends and advancements in relevant scientific fields. * Propose new research ideas and approaches based on findings from literature and experimental results. Project Management: * Assist in managing timelines and project deliverables to ensure research objectives are met. * Contribute to project documentation, including protocols, reports, and presentations. Equipment Maintenance: * Operate and maintain laboratory equipment, ensuring proper calibration and functionality. * Assist in troubleshooting and resolving technical issues related to experimental procedures. Training and Mentorship: * Support the training of interns, junior scientists, and lab personnel on laboratory techniques and safety protocols. * Foster a collaborative and supportive laboratory environment. Experience/Education * Bachelor's degree in Life Sciences, Chemistry, Biotechnology, or a related field * 0 - 1 year of professional experience. Knowledge & Skillsets Required * Familiarity with laboratory techniques such as PCR, chromatography, cell culture, and analytical assays. * Strong analytical skills and proficiency in data analysis software (e.g., Excel, GraphPad, statistical software). * Excellent written and verbal communication skills. * Ability to work independently and as part of a team. Mesa Labs is an Equal Employment Opportunity Employer. Mesa Labs prohibits unlawful discrimination and harassment against applicants or employees based on age, race, sex, color, religion, creed, national origin or ancestry, disability, military status, sexual orientation, or any other status protected by applicable state or local law. Please note that Mesa Labs conducts criminal background checks upon offer acceptance.

About KariusKarius is a life science, venture-backed clinical metagenomics company, focused on elevating patient care through microbial insights. We are committed to advancing diagnostic science and technology to optimize the diagnosis and treatment of infectious diseases. Through the use of genomics and AI, we are driven to improve the diagnostic landscape for infectious diseases. Karius delivers unprecedented diagnostic insight detecting microbial cell-free DNA circulating in the body to assist physicians to make rapid treatment decisions. Why Should You Join Us?Karius' core mission is to conquer infectious diseases through innovations around genomic sequencing and machine learning. The company's platform is already delivering unprecedented insight into the microbial landscape, providing clinicians with a comprehensive test capable of identifying more than a thousand pathogens directly from blood. Through this journey, we realized that the microbial cell-free DNA platform may hold value that goes well beyond the direct diagnosis of infections. You, as part of the Karius team, will be able to see the immense opportunity to expand the human knowledge around this emerging topic and apply it directly to critical problems in human health and disease. Position SummaryYou are highly curious and creative and desire to continuously grow and improve in your goal to make an impact on patients. You will be a key member of the Assay Development Analytics (ADA) team that helps drive the computational aspects of assay development, focusing on analysis and optimization of new chemistries and lab techniques. You will participate in experimental design, conduct thoughtful computational analyses by determining the analysis plan and executing it using the necessary tools and methodologies. You will work closely with colleagues in Molecular Biology to understand and deliver on our shared goals. You are a self-starter and always like to find ways to make things better. Reports to: Sr. Manager, Bioinformatics Location: Redwood City, CA or hybrid or remote Primary Responsibilities• Individual contributor to Assay Development Analytics (ADA), which drives the computational aspects of assay development, focusing on analysis and optimization of new chemistries and lab techniques.• Participate in experimental design, conduct computational analyses, understand rationale, set the analysis plan, and execute using the necessary tools and methodologies to deliver innovative assays.• Work closely with colleagues across the Molecular Biology and Laboratory Operations teams to understand the properties of the assays and ways to improve our technologies.• Continue to grow and learn in the necessary mathematical, technological, and software aspects of the field through internal knowledge acquisition and staying current with the latest relevant literature.• Open to exploring multiple approaches for problem-solving and modeling including borrowing across a wide range of quantitative disciplines.• Ensure high standards of data integrity, quality control, and validation, while maintaining rigorous quality documentation and dissemination of scientific findings.• Provide clear visibility into areas of ownership and communicate weekly progress and results to stakeholders.• Continue to grow and learn in the necessary biological/scientific domains and technological aspects of the field through novel knowledge acquisition but also staying current with the latest relevant literature.• Share a passion for ensuring the quality of our statistical analysis, via reliability, reproducibility, and rigor. What's Fun About the Job?Karius is operating at the edge of what is now known to be possible in infectious disease diagnostics. With that, comes a wave of new and incredible challenges and opportunities. To deliver on that value, you will be tapping into some of the most advanced technologies, architecting and innovating where the current solutions simply don't suffice. You will get to see how much your work really matters. Travel: Travel to HQ on a quarterly basis if remote. Physical RequirementsSubject to extended periods of sitting and/or standing, vision to monitor, and moderate noise levels. Work is performed in an office environment. Position Requirements• Ph.D. in computer science, statistics, mathematics, physics, genetics, bioinformatics, metagenomics, or related fields (preferably with a focus on computational biology or machine learning) with 3+ years of postdoctoral and/or industry experience; OR Master's degree with 5+ years of directly relevant industry experience.• Publications demonstrating innovative investigation and interpretation of biological data. • Proven proficiency, and understanding of, modern statistics and machine learning.• Proven proficiency with high-dimensional, large-scale datasets characterized by low signal-to-noise.• Demonstrated excellence in communication and collaboration within cross-functional, multidisciplinary teams.• Self-starter with the ability to independently drive results and influence project direction.• Evidence of innovation in connecting biological insights to complex mechanisms of microbiome and host-environment interactions.• Familiarity with a range of relevant laboratory techniques (either through hands-on work or from collaborations with laboratory-focused colleagues).• Familiarity and experience with bioinformatics tools, approaches, and workflows, particularly those related to next-generation sequencing data analysis.• Familiarity with design of experiments (DOE) approaches to optimize process settings. Personal Qualifications• Passionate, purpose-driven, and excited about Karius' mission: to conquer infectious diseases through innovations around genomic sequencing and machine learning.• Excellence at communication and collaboration within a cross-functional team.• Detail oriented with exceptional organizational and time management skills.• Self-starting mentality and ability to drive results.• Comfortable working in an environment which combines both research aspects as well as development.• Ability to work effectively and efficiently in a fast-paced (startup) environment. DisclaimerThe above is intended to describe the general nature and level of work being performed by individuals assigned to this position. It is not intended to be an exhaustive list of all duties, responsibilities, and skills required. Responsibilities and duties may change or be adjusted to meet the needs of the company, and additional duties may be assigned as necessary. The job description is subject to change at any time at the discretion of Karius. Equal Opportunity EmployerAt Karius, we value a diverse and inclusive workplace and provide equal employment opportunities for all applicants and employees and are committed to honor and invest in the full diversity of people, in our hiring, recruiting and development of employees across the Company. All qualified applicants for employment are encouraged to apply and will be considered without regard to an individual's race, color, sex, gender identity and gender expression (including transgender individuals who are transitioning, have transitioned, or are perceived to be transitioning to the gender with which they identify), religion, age, national origin or ancestry, citizenship, physical or mental disability, medical condition, family care status, marital status, domestic partner status, sexual orientation, genetic information, military or veteran status, or any other basis protected by federal, state or local laws. If you are unable to submit your application due to a disability, please contact us at *********************** and we will accommodate qualified individuals with disabilities.

About KariusKarius is a life science, venture-backed clinical metagenomics company, focused on elevating patient care through microbial insights. We are committed to advancing diagnostic science and technology to optimize the diagnosis and treatment of infectious diseases. Through the use of genomics and AI, we are driven to improve the diagnostic landscape for infectious diseases. Karius delivers unprecedented diagnostic insight detecting microbial cell-free DNA circulating in the body to assist physicians to make rapid treatment decisions. Why Should You Join Us?Karius' core mission is to conquer infectious diseases through innovations around genomic sequencing and machine learning. The company's platform is already delivering unprecedented insight into the microbial landscape, providing clinicians with a comprehensive test capable of identifying more than a thousand pathogens directly from blood. Through this journey, we realized that the microbial cell-free DNA platform may hold value that goes well beyond the direct diagnosis of infections. You, as part of the Karius team, will be able to see the immense opportunity to expand the human knowledge around this emerging topic and apply it directly to critical problems in human health and disease. Position SummaryYou are highly curious, creative, and driven by a desire for continuous growth with the ultimate goal of making a meaningful impact on patients' lives. As a key and integral member of the Computational Biomarker Discovery team, you will focus on deeply exploring and analyzing the complex biological interplay between diverse conditions and molecular data. In this role, you will help unlock and help unlock preliminary biological signatures to inform translational science and precision medicine beyond the conventional infectious disease arena, and into areas such as autoimmune and cancer. You will design analysis plans, execute computational workflows, partner for method and machine learning model development, and integrate biological rationale with data-driven insights to uncover meaningful connections. You bring a passion for applying technology in novel ways, generating innovative hypotheses, and revealing hidden patterns in data. Your curiosity and analytical rigor will drive discoveries that push the boundaries of biomarker research and patient care. Reports to: Director, Computational Biomarker Discovery Location: Redwood City, CA (Hybrid) or Remote (USA) Primary Responsibilities• Lead data analysis and interpretation of complex biological datasets, including next-generation sequencing (NGS), metagenomics, transcriptomics, fragmentomics, and single-cell analysis.• Create or adapt computational tools and algorithms to support biomarker discovery and workflows.• Drive bioinformatics aspects of cross-functional research projects in collaboration with scientific and medical leaders, under the guidance of the Director of Computational Biomarker Discovery.• Conduct deep exploration of the biological interplay between molecular data and disease conditions, generating insights to advance translational science.• Deliver preliminary biological signatures that inform precision medicine applications beyond infectious disease, including autoimmune disorders and oncology.• Partner in experimental design by defining analysis plans, selecting appropriate methodologies, and executing computational analyses with a strong grounding in biological rationale.• Collaborate closely with scientific, medical, engineering, and commercial teams to set company goals and support the development of new partnerships and products.• Ensure high standards of data integrity, quality control, and validation, while maintaining rigorous quality documentation and dissemination of scientific findings.• Provide clear visibility into areas of ownership and communicate weekly progress and results to stakeholders.• Continue to grow and learn in the necessary biological/scientific domains and technological aspects of the field through novel knowledge acquisition but also staying current with the latest relevant literature.• Share enthusiasm for exploring novel applications of Karius' technology platform to drive innovation and impact. What's Fun About the Job?Karius is operating at the edge of what is now known to be possible in infectious disease diagnostics. With that, comes a wave of new and incredible challenges and opportunities. To deliver on that value, you will be tapping into some of the most advanced technologies, architecting and innovating where the current solutions simply don't suffice. You will get to see how much your work really matters. Travel: Travel to HQ on a quarterly basis if remote. Physical RequirementsSubject to extended periods of sitting and/or standing, vision to monitor, and moderate noise levels. Work is performed in an office environment. Position Requirements• Ph.D. in computer science, statistics, mathematics, physics, genetics, bioinformatics, metagenomics, or related fields (preferably with a focus on computational biology or machine learning) with 3+ years of postdoctoral and/or industry experience; OR Master's degree with 5+ years of directly relevant industry experience.• Publications demonstrating the use of innovative mathematical or computational models to investigate and interpret biological and biomarker data.• Strong background in modern statistics and machine learning, including applications to biomarker discovery.• Proven proficiency with high-dimensional, large-scale datasets characterized by low signal-to-noise.• Demonstrated excellence in communication and collaboration within cross-functional, multidisciplinary teams.• Self-starter with the ability to independently drive results and influence project direction.• Evidence of innovation in connecting biological insights to complex mechanisms of microbiome and host-environment interactions.• Deep understanding and hands-on experience with bioinformatics tools, methods, and workflows, especially those related to next-generation sequencing (NGS) data analysis.• Familiarity with exploratory study and clinical trial designs and analyses, particularly in pharmaceutical or biotechnology applications. Personal Qualifications• Passionate, purpose-driven, and excited about Karius' mission: to conquer infectious diseases through innovations around genomic sequencing and machine learning.• Excellence at communication and collaboration within a cross-functional team.• Detail oriented with exceptional organizational and time management skills.• Self-starting mentality and ability to drive results.• Comfortable working in an environment which combines both research aspects as well as development.• Ability to work effectively and efficiently in a fast-paced (startup) environment. DisclaimerThe above is intended to describe the general nature and level of work being performed by individuals assigned to this position. It is not intended to be an exhaustive list of all duties, responsibilities, and skills required. Responsibilities and duties may change or be adjusted to meet the needs of the company, and additional duties may be assigned as necessary. The job description is subject to change at any time at the discretion of Karius. Equal Opportunity EmployerAt Karius, we value a diverse and inclusive workplace and provide equal employment opportunities for all applicants and employees and are committed to honor and invest in the full diversity of people, in our hiring, recruiting and development of employees across the Company. All qualified applicants for employment are encouraged to apply and will be considered without regard to an individual's race, color, sex, gender identity and gender expression (including transgender individuals who are transitioning, have transitioned, or are perceived to be transitioning to the gender with which they identify), religion, age, national origin or ancestry, citizenship, physical or mental disability, medical condition, family care status, marital status, domestic partner status, sexual orientation, genetic information, military or veteran status, or any other basis protected by federal, state or local laws. If you are unable to submit your application due to a disability, please contact us at *********************** and we will accommodate qualified individuals with disabilities.

The Center for Cancer Genomics (CCG) at Dana-Farber Cancer Institute facilitates genomic discoveries in cancer using novel technology platforms to assist researchers in both genome-wide and gene-focused efforts. Technologies are selected and developed with a view to research-oriented ventures, as well as translational medicine and clinical relevance. Our clinical and research environments currently use state-of-the-art massively parallel sequencing assays of DNA and RNA from patient tumor samples. Data from these environments are used to advance research on both adult and pediatric cancers, improve our understanding of cancer biology, and advance the field of precision cancer medicine. This opportunity offers the chance to work at the forefront of translational cancer technologies and applications, in an informatics group that enables analyses in both arenas. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. Responsibilities The Bioinformatician II will report to CCG's Lead Informaticist and have the main responsibility of independently performing data analysis on a wide array of cancer multiomics projects (sc/sn RNAseq, sc ATACseq, Crispr screens, SNV/CNV, longread Oxford Nanopore Direct RNA sequencing, etc.) in consultation and collaboration with internal Dana-Farber research collaborators and external research partners. Some limited orchestration of automated pipelines may be required as necessary. The Bioinformatician II will have no direct reports. Dana-Farber has a wealth of local, on-premises, and cloud-based computing resources available to extensively explore the large body of data generated annually by Dana-Farber researchers and collaborators. Given these resources, the development of novel computational methods is strongly encouraged. Qualifications MINIMUM JOB QUALIFICATIONS: Minimum Education: Bachelor's degree required in a STEM field. Master's degree or PhD strongly preferred in bioinformatics, medical informatics, computational biology, statistics, computer science/engineering, or a related quantitative field. Minimum Education: 3 Years of experience required; Master's degree with 1 year experience required; PhD with 0 years. * Experience with bioinformatics tools and databases for sequence alignment/analysis; germline and somatic variant calling; bulk and single-cell/nuclei RNAseq; long read sequencing (Oxford Nanopore). * Proficiency in programming languages commonly used in bioinformatics and data analysis, such as Python, R, and Perl. Experience with workflow languages such as WDL or Nextflow is a plus. * Excellent communication skills and ability to work collaboratively in multi-disciplinary team. Pay Transparency Statement The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications. For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA) $83,800 - $90,800 At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply. Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law. EEOC Poster

The **Center for Cancer Genomics** **(CCG)** at Dana-Farber Cancer Institute facilitates genomic discoveries in cancer using novel technology platforms to assist researchers in both genome-wide and gene-focused efforts. Technologies are selected and developed with a view to research-oriented ventures, as well as translational medicine and clinical relevance. Our clinical and research environments currently use state-of-the-art massively parallel sequencing assays of DNA and RNA from patient tumor samples. Data from these environments are used to advance research on both adult and pediatric cancers, improve our understanding of cancer biology, and advance the field of precision cancer medicine. This opportunity offers the chance to work at the forefront of translational cancer technologies and applications, in an informatics group that enables analyses in both arenas. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. The **Bioinformatician II** will report to CCG's Lead Informaticist and have the main responsibility of independently performing data analysis on a wide array of cancer multiomics projects ( _sc/sn RNAseq, sc ATACseq, Crispr screens, SNV/CNV, longread Oxford Nanopore Direct RNA sequencing,_ etc.) in consultation and collaboration with internal Dana-Farber research collaborators and external research partners. Some limited orchestration of automated pipelines may be required as necessary. The Bioinformatician II will have no direct reports. Dana-Farber has a wealth of local, on-premises, and cloud-based computing resources available to extensively explore the large body of data generated annually by Dana-Farber researchers and collaborators. Given these resources, the development of novel computational methods is strongly encouraged. **MINIMUM JOB QUALIFICATIONS:** Minimum Education: Bachelor's degree required in a STEM field. Master's degree or PhD strongly preferred in bioinformatics, medical informatics, computational biology, statistics, computer science/engineering, or a related quantitative field. Minimum Education: 3 Years of experience required; Master's degree with 1 year experience required; PhD with 0 years. + Experience with bioinformatics tools and databases for sequence alignment/analysis; germline and somatic variant calling; bulk and single-cell/nuclei RNAseq; long read sequencing (Oxford Nanopore). + Proficiency in programming languages commonly used in bioinformatics and data analysis, such as Python, R, and Perl. Experience with workflow languages such as WDL or Nextflow is a plus. + Excellent communication skills and ability to work collaboratively in multi-disciplinary team. **Pay Transparency Statement** The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications. For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA) $83,800 - $90,800 At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply. Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law. **EEOC Poster**

Karius is a life science, venture-backed clinical metagenomics company, focused on elevating patient care through microbial insights. We are committed to advancing diagnostic science and technology to optimize the diagnosis and treatment of infectious diseases. Through the use of genomics and AI, we are driven to improve the diagnostic landscape for infectious diseases. Karius delivers unprecedented diagnostic insight detecting microbial cell-free DNA circulating in the body to assist physicians to make rapid treatment decisions. Why Should You Join Us? Karius' core mission is to conquer infectious diseases through innovations around genomic sequencing and machine learning. The company's platform is already delivering unprecedented insight into the microbial landscape, providing clinicians with a comprehensive test capable of identifying more than a thousand pathogens directly from blood. Through this journey, we realized that the microbial cell-free DNA platform may hold value that goes well beyond the direct diagnosis of infections. You, as part of the Karius team, will be able to see the immense opportunity to expand the human knowledge around this emerging topic and apply it directly to critical problems in human health and disease. Position Summary You are highly curious and creative and desire to continuously grow and improve in your goal to make an impact on patients. You will be a key member of the Assay Development Analytics (ADA) team that helps drive the computational aspects of assay development, focusing on analysis and optimization of new chemistries and lab techniques. You will participate in experimental design, conduct thoughtful computational analyses by determining the analysis plan and executing it using the necessary tools and methodologies. You will work closely with colleagues in Molecular Biology to understand and deliver on our shared goals. You are a self-starter and always like to find ways to make things better. Reports to: Sr. Manager, Bioinformatics Location: Redwood City, CA or hybrid or remote Primary Responsibilities * Individual contributor to Assay Development Analytics (ADA), which drives the computational aspects of assay development, focusing on analysis and optimization of new chemistries and lab techniques. * Participate in experimental design, conduct computational analyses, understand rationale, set the analysis plan, and execute using the necessary tools and methodologies to deliver innovative assays. * Work closely with colleagues across the Molecular Biology and Laboratory Operations teams to understand the properties of the assays and ways to improve our technologies. * Continue to grow and learn in the necessary mathematical, technological, and software aspects of the field through internal knowledge acquisition and staying current with the latest relevant literature. * Open to exploring multiple approaches for problem-solving and modeling including borrowing across a wide range of quantitative disciplines. * Ensure high standards of data integrity, quality control, and validation, while maintaining rigorous quality documentation and dissemination of scientific findings. * Provide clear visibility into areas of ownership and communicate weekly progress and results to stakeholders. * Continue to grow and learn in the necessary biological/scientific domains and technological aspects of the field through novel knowledge acquisition but also staying current with the latest relevant literature. * Share a passion for ensuring the quality of our statistical analysis, via reliability, reproducibility, and rigor. What's Fun About the Job? Karius is operating at the edge of what is now known to be possible in infectious disease diagnostics. With that, comes a wave of new and incredible challenges and opportunities. To deliver on that value, you will be tapping into some of the most advanced technologies, architecting and innovating where the current solutions simply don't suffice. You will get to see how much your work really matters. Travel: Travel to HQ on a quarterly basis if remote. Physical Requirements Subject to extended periods of sitting and/or standing, vision to monitor, and moderate noise levels. Work is performed in an office environment. Position Requirements * Ph.D. in computer science, statistics, mathematics, physics, genetics, bioinformatics, metagenomics, or related fields (preferably with a focus on computational biology or machine learning) with 3+ years of postdoctoral and/or industry experience; OR Master's degree with 5+ years of directly relevant industry experience. * Publications demonstrating innovative investigation and interpretation of biological data. * Proven proficiency, and understanding of, modern statistics and machine learning. * Proven proficiency with high-dimensional, large-scale datasets characterized by low signal-to-noise. * Demonstrated excellence in communication and collaboration within cross-functional, multidisciplinary teams. * Self-starter with the ability to independently drive results and influence project direction. * Evidence of innovation in connecting biological insights to complex mechanisms of microbiome and host-environment interactions. * Familiarity with a range of relevant laboratory techniques (either through hands-on work or from collaborations with laboratory-focused colleagues). * Familiarity and experience with bioinformatics tools, approaches, and workflows, particularly those related to next-generation sequencing data analysis. * Familiarity with design of experiments (DOE) approaches to optimize process settings. Personal Qualifications * Passionate, purpose-driven, and excited about Karius' mission: to conquer infectious diseases through innovations around genomic sequencing and machine learning. * Excellence at communication and collaboration within a cross-functional team. * Detail oriented with exceptional organizational and time management skills. * Self-starting mentality and ability to drive results. * Comfortable working in an environment which combines both research aspects as well as development. * Ability to work effectively and efficiently in a fast-paced (startup) environment. Disclaimer The above is intended to describe the general nature and level of work being performed by individuals assigned to this position. It is not intended to be an exhaustive list of all duties, responsibilities, and skills required. Responsibilities and duties may change or be adjusted to meet the needs of the company, and additional duties may be assigned as necessary. The job description is subject to change at any time at the discretion of Karius. Equal Opportunity Employer At Karius, we value a diverse and inclusive workplace and provide equal employment opportunities for all applicants and employees and are committed to honor and invest in the full diversity of people, in our hiring, recruiting and development of employees across the Company. All qualified applicants for employment are encouraged to apply and will be considered without regard to an individual's race, color, sex, gender identity and gender expression (including transgender individuals who are transitioning, have transitioned, or are perceived to be transitioning to the gender with which they identify), religion, age, national origin or ancestry, citizenship, physical or mental disability, medical condition, family care status, marital status, domestic partner status, sexual orientation, genetic information, military or veteran status, or any other basis protected by federal, state or local laws. If you are unable to submit your application due to a disability, please contact us at [email protected] and we will accommodate qualified individuals with disabilities. $142,231 - $213,347 a year

About KariusKarius is a life science, venture-backed clinical metagenomics company, focused on elevating patient care through microbial insights. We are committed to advancing diagnostic science and technology to optimize the diagnosis and treatment of infectious diseases. Through the use of genomics and AI, we are driven to improve the diagnostic landscape for infectious diseases. Karius delivers unprecedented diagnostic insight detecting microbial cell-free DNA circulating in the body to assist physicians to make rapid treatment decisions. Why Should You Join Us?Karius' core mission is to conquer infectious diseases through innovations around genomic sequencing and machine learning. The company's platform is already delivering unprecedented insight into the microbial landscape, providing clinicians with a comprehensive test capable of identifying more than a thousand pathogens directly from blood. Through this journey, we realized that the microbial cell-free DNA platform may hold value that goes well beyond the direct diagnosis of infections. You, as part of the Karius team, will be able to see the immense opportunity to expand the human knowledge around this emerging topic and apply it directly to critical problems in human health and disease. Position SummaryYou are highly curious and creative and desire to continuously grow and improve in your goal to make an impact on patients. You will be a key member of the Assay Development Analytics (ADA) team that helps drive the computational aspects of assay development, focusing on analysis and optimization of new chemistries and lab techniques. You will participate in experimental design, conduct thoughtful computational analyses by determining the analysis plan and executing it using the necessary tools and methodologies. You will work closely with colleagues in Molecular Biology to understand and deliver on our shared goals. You are a self-starter and always like to find ways to make things better. Reports to: Sr. Manager, Bioinformatics Location: Redwood City, CA or hybrid or remote Primary Responsibilities• Individual contributor to Assay Development Analytics (ADA), which drives the computational aspects of assay development, focusing on analysis and optimization of new chemistries and lab techniques.• Participate in experimental design, conduct computational analyses, understand rationale, set the analysis plan, and execute using the necessary tools and methodologies to deliver innovative assays.• Work closely with colleagues across the Molecular Biology and Laboratory Operations teams to understand the properties of the assays and ways to improve our technologies.• Continue to grow and learn in the necessary mathematical, technological, and software aspects of the field through internal knowledge acquisition and staying current with the latest relevant literature.• Open to exploring multiple approaches for problem-solving and modeling including borrowing across a wide range of quantitative disciplines.• Ensure high standards of data integrity, quality control, and validation, while maintaining rigorous quality documentation and dissemination of scientific findings.• Provide clear visibility into areas of ownership and communicate weekly progress and results to stakeholders.• Continue to grow and learn in the necessary biological/scientific domains and technological aspects of the field through novel knowledge acquisition but also staying current with the latest relevant literature.• Share a passion for ensuring the quality of our statistical analysis, via reliability, reproducibility, and rigor. What's Fun About the Job?Karius is operating at the edge of what is now known to be possible in infectious disease diagnostics. With that, comes a wave of new and incredible challenges and opportunities. To deliver on that value, you will be tapping into some of the most advanced technologies, architecting and innovating where the current solutions simply don't suffice. You will get to see how much your work really matters. Travel: Travel to HQ on a quarterly basis if remote. Physical RequirementsSubject to extended periods of sitting and/or standing, vision to monitor, and moderate noise levels. Work is performed in an office environment. Position Requirements• Ph.D. in computer science, statistics, mathematics, physics, genetics, bioinformatics, metagenomics, or related fields (preferably with a focus on computational biology or machine learning) with 3+ years of postdoctoral and/or industry experience; OR Master's degree with 5+ years of directly relevant industry experience.• Publications demonstrating innovative investigation and interpretation of biological data. • Proven proficiency, and understanding of, modern statistics and machine learning.• Proven proficiency with high-dimensional, large-scale datasets characterized by low signal-to-noise.• Demonstrated excellence in communication and collaboration within cross-functional, multidisciplinary teams.• Self-starter with the ability to independently drive results and influence project direction.• Evidence of innovation in connecting biological insights to complex mechanisms of microbiome and host-environment interactions.• Familiarity with a range of relevant laboratory techniques (either through hands-on work or from collaborations with laboratory-focused colleagues).• Familiarity and experience with bioinformatics tools, approaches, and workflows, particularly those related to next-generation sequencing data analysis.• Familiarity with design of experiments (DOE) approaches to optimize process settings. Personal Qualifications• Passionate, purpose-driven, and excited about Karius' mission: to conquer infectious diseases through innovations around genomic sequencing and machine learning.• Excellence at communication and collaboration within a cross-functional team.• Detail oriented with exceptional organizational and time management skills.• Self-starting mentality and ability to drive results.• Comfortable working in an environment which combines both research aspects as well as development.• Ability to work effectively and efficiently in a fast-paced (startup) environment. DisclaimerThe above is intended to describe the general nature and level of work being performed by individuals assigned to this position. It is not intended to be an exhaustive list of all duties, responsibilities, and skills required. Responsibilities and duties may change or be adjusted to meet the needs of the company, and additional duties may be assigned as necessary. The job description is subject to change at any time at the discretion of Karius. Equal Opportunity EmployerAt Karius, we value a diverse and inclusive workplace and provide equal employment opportunities for all applicants and employees and are committed to honor and invest in the full diversity of people, in our hiring, recruiting and development of employees across the Company. All qualified applicants for employment are encouraged to apply and will be considered without regard to an individual's race, color, sex, gender identity and gender expression (including transgender individuals who are transitioning, have transitioned, or are perceived to be transitioning to the gender with which they identify), religion, age, national origin or ancestry, citizenship, physical or mental disability, medical condition, family care status, marital status, domestic partner status, sexual orientation, genetic information, military or veteran status, or any other basis protected by federal, state or local laws. If you are unable to submit your application due to a disability, please contact us at [email protected] and we will accommodate qualified individuals with disabilities. $142,231 - $213,347 a year

About KariusKarius is a life science, venture-backed clinical metagenomics company, focused on elevating patient care through microbial insights. We are committed to advancing diagnostic science and technology to optimize the diagnosis and treatment of infectious diseases. Through the use of genomics and AI, we are driven to improve the diagnostic landscape for infectious diseases. Karius delivers unprecedented diagnostic insight detecting microbial cell-free DNA circulating in the body to assist physicians to make rapid treatment decisions. Why Should You Join Us?Karius' core mission is to conquer infectious diseases through innovations around genomic sequencing and machine learning. The company's platform is already delivering unprecedented insight into the microbial landscape, providing clinicians with a comprehensive test capable of identifying more than a thousand pathogens directly from blood. Through this journey, we realized that the microbial cell-free DNA platform may hold value that goes well beyond the direct diagnosis of infections. You, as part of the Karius team, will be able to see the immense opportunity to expand the human knowledge around this emerging topic and apply it directly to critical problems in human health and disease. Position SummaryYou are highly curious, creative, and driven by a desire for continuous growth with the ultimate goal of making a meaningful impact on patients' lives. As a key and integral member of the Computational Biomarker Discovery team, you will focus on deeply exploring and analyzing the complex biological interplay between diverse conditions and molecular data. In this role, you will help unlock and help unlock preliminary biological signatures to inform translational science and precision medicine beyond the conventional infectious disease arena, and into areas such as autoimmune and cancer. You will design analysis plans, execute computational workflows, partner for method and machine learning model development, and integrate biological rationale with data-driven insights to uncover meaningful connections. You bring a passion for applying technology in novel ways, generating innovative hypotheses, and revealing hidden patterns in data. Your curiosity and analytical rigor will drive discoveries that push the boundaries of biomarker research and patient care. Reports to: Director, Computational Biomarker Discovery Location: Redwood City, CA (Hybrid) or Remote (USA) Primary Responsibilities• Lead data analysis and interpretation of complex biological datasets, including next-generation sequencing (NGS), metagenomics, transcriptomics, fragmentomics, and single-cell analysis.• Create or adapt computational tools and algorithms to support biomarker discovery and workflows.• Drive bioinformatics aspects of cross-functional research projects in collaboration with scientific and medical leaders, under the guidance of the Director of Computational Biomarker Discovery.• Conduct deep exploration of the biological interplay between molecular data and disease conditions, generating insights to advance translational science.• Deliver preliminary biological signatures that inform precision medicine applications beyond infectious disease, including autoimmune disorders and oncology.• Partner in experimental design by defining analysis plans, selecting appropriate methodologies, and executing computational analyses with a strong grounding in biological rationale.• Collaborate closely with scientific, medical, engineering, and commercial teams to set company goals and support the development of new partnerships and products.• Ensure high standards of data integrity, quality control, and validation, while maintaining rigorous quality documentation and dissemination of scientific findings.• Provide clear visibility into areas of ownership and communicate weekly progress and results to stakeholders.• Continue to grow and learn in the necessary biological/scientific domains and technological aspects of the field through novel knowledge acquisition but also staying current with the latest relevant literature.• Share enthusiasm for exploring novel applications of Karius' technology platform to drive innovation and impact. What's Fun About the Job?Karius is operating at the edge of what is now known to be possible in infectious disease diagnostics. With that, comes a wave of new and incredible challenges and opportunities. To deliver on that value, you will be tapping into some of the most advanced technologies, architecting and innovating where the current solutions simply don't suffice. You will get to see how much your work really matters. Travel: Travel to HQ on a quarterly basis if remote. Physical RequirementsSubject to extended periods of sitting and/or standing, vision to monitor, and moderate noise levels. Work is performed in an office environment. Position Requirements• Ph.D. in computer science, statistics, mathematics, physics, genetics, bioinformatics, metagenomics, or related fields (preferably with a focus on computational biology or machine learning) with 3+ years of postdoctoral and/or industry experience; OR Master's degree with 5+ years of directly relevant industry experience.• Publications demonstrating the use of innovative mathematical or computational models to investigate and interpret biological and biomarker data.• Strong background in modern statistics and machine learning, including applications to biomarker discovery.• Proven proficiency with high-dimensional, large-scale datasets characterized by low signal-to-noise.• Demonstrated excellence in communication and collaboration within cross-functional, multidisciplinary teams.• Self-starter with the ability to independently drive results and influence project direction.• Evidence of innovation in connecting biological insights to complex mechanisms of microbiome and host-environment interactions.• Deep understanding and hands-on experience with bioinformatics tools, methods, and workflows, especially those related to next-generation sequencing (NGS) data analysis.• Familiarity with exploratory study and clinical trial designs and analyses, particularly in pharmaceutical or biotechnology applications. Personal Qualifications• Passionate, purpose-driven, and excited about Karius' mission: to conquer infectious diseases through innovations around genomic sequencing and machine learning.• Excellence at communication and collaboration within a cross-functional team.• Detail oriented with exceptional organizational and time management skills.• Self-starting mentality and ability to drive results.• Comfortable working in an environment which combines both research aspects as well as development.• Ability to work effectively and efficiently in a fast-paced (startup) environment. DisclaimerThe above is intended to describe the general nature and level of work being performed by individuals assigned to this position. It is not intended to be an exhaustive list of all duties, responsibilities, and skills required. Responsibilities and duties may change or be adjusted to meet the needs of the company, and additional duties may be assigned as necessary. The job description is subject to change at any time at the discretion of Karius. Equal Opportunity EmployerAt Karius, we value a diverse and inclusive workplace and provide equal employment opportunities for all applicants and employees and are committed to honor and invest in the full diversity of people, in our hiring, recruiting and development of employees across the Company. All qualified applicants for employment are encouraged to apply and will be considered without regard to an individual's race, color, sex, gender identity and gender expression (including transgender individuals who are transitioning, have transitioned, or are perceived to be transitioning to the gender with which they identify), religion, age, national origin or ancestry, citizenship, physical or mental disability, medical condition, family care status, marital status, domestic partner status, sexual orientation, genetic information, military or veteran status, or any other basis protected by federal, state or local laws. If you are unable to submit your application due to a disability, please contact us at [email protected] and we will accommodate qualified individuals with disabilities. $142,231 - $213,347 a year

Ready to redefine what's possible in molecular diagnostics? Join a team of brilliant, passionate innovators who wake up every day determined to transform healthcare. At BillionToOne, we've built something extraordinary-a culture where transparency fuels trust, collaboration drives breakthroughs, and every voice matters in our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we strive to build products that are 10x better than anything that exists today. Our people are our greatest asset: talented scientists, engineers, sales professionals, and visionaries united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion-every innovation you contribute helps remove fear of unknown from some of life's most critical medical moments. If you're driven by purpose, energized by innovation, and ready to help build the future of precision medicine, this is where you belong. We are looking for a Senior Bioinformatics Scientist to join a fast growing team. This person will be responsible for the generation, analysis, and communication of clinical next-generation DNA sequencing data for the Northstar oncology products. Our sample volume is growing extremely quickly, and this role will own the further development of our analysis pipeline to analyze tens of thousands of samples, and be the lead scientist for everything related to our bioinformatics analyses. The Senior Bioinformatics Scientist role is a full-time onsite position and reports to the Senior Manager of Bioinformatics, Oncology. Responsibilities: Develop sophisticated and robust NGS analysis pipelines capable of processing tens of thousands of samples Develop tests and test frameworks for NGS pipelines Analyze and troubleshoot clinical NGS data Analyze assay performance and contribute to publications that demonstrate the clinical validity and utility of our tests Design new quality metrics and processes for clinical molecular diagnostic assays Collaborate with R&D scientists to generate new scientific insights Communicate assay performance and capabilities to clinical personnel at weekly meetings and to other non-clinical stakeholders Qualifications: PhD in Bioinformatics, Computational Biology, Computer Science, Bioengineering, Physics or related fields 2+ years of experience developing robust and scalable bioinformatics pipelines 2+ years of experience analyzing NGS data Fluency in Python Experience with Linux environment, GitHub and AWS Excellent communication and presentation skills, ability to work across functional teams and with non-experts Nice-To-Haves: Start-up experience Experience working in a regulated environment Experience with CI/CD pipelines and dockerized code deployment Experience with cloud infrastructure management with infrastructure as code such as CDK Benefits And Perks: Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients Open, transparent culture that includes weekly Town Hall meetings The ability to indirectly or directly change the lives of hundreds of thousands patients Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80% Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%) Supplemental fertility benefits coverage Retirement savings program including a 4% Company match Increase paid time off with increased tenure Latest and greatest hardware (laptop, lab equipment, facilities) Free daily on-site lunches provided from top eateries A variety of perks on campus (state of the art gym, restaurant) Free on-site EV charging (compatible with all EVs, including Tesla) At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.). For this position, we offer a total compensation package of $244,805 per year, including a base pay range of $156,060 - $176,868 per year. BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. For more information about how we protect your information, we encourage you to review our Privacy Policy. About BillionToOne BillionToOne is a next-generation molecular diagnostics company on a mission to make powerful, accurate diagnostic tests accessible to everyone. Our revolutionary QCT molecular counting technology enhances disease detection resolution by over a thousandfold using cell-free DNA-a breakthrough that's already transformed the lives of over half a million patients worldwide. Our Impact: We've pioneered game-changing diagnostic solutions that are redefining industry standards. Unity Complete™ stands as the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample. In oncology, our Northstar liquid biopsy test uniquely combines treatment selection with real-time monitoring, giving oncologists unprecedented precision in cancer care. Our Growth: From $0 to $125 million in Annual Recurring Revenue in just four years. We've raised close to $400 million in funding, including a $130 million Series D round in June 2024, achieving a valuation of over $1 billion. This backing comes from world-class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest. Our Recognition: Forbes recently named us one of America's Best Startup Employers for 2025, and we were awarded Great Place to Work certification in 2024-with an incredible 100% of our people reporting they are willing to give extra to get the job done. These honors recognize not just our innovation but the exceptional culture we've cultivated-one that remains authentically collaborative and transparent even as we've scaled. Our Future: Headquartered in Menlo Park with facilities in Union City, California, we're continuing to push the boundaries of what's possible in molecular diagnostics. Recent clinical outcomes data for Unity Fetal Risk Screen and new advances in cancer diagnostics prove we're just getting started. At BillionToOne, you'll join a diverse team of passionate innovators who believe that the best science happens when brilliant minds collaborate openly, think boldly, and never lose sight of the patients whose lives depend on our work. Ready to help us change the world, one diagnosis at a time? Learn more at ********************

HealthPartners Institute is seeking a Physician Research Investigator - Dementia Research with both clinical and research experience in Alzheimer's disease and related dementias, age-related cognitive decline, or dementia caregiving. Candidates with prior experience in investigator-initiated clinical trials are strongly encouraged to apply. Applicants with expertise in health services research, clinical decision support, or implementation science will also be considered. Research Investigators at HealthPartners Institute may obtain or maintain external academic appointments. Eligible candidates would be encouraged to practice part-time as a neurologist or geriatrician within the HealthPartners Center for Memory & Aging, as part of a multidisciplinary team caring for people with dementia. At HealthPartners Institute, Researcher Investigators are expected to support and develop externally funded research programs, conduct nationally and internationally recognized scholarly clinical or health services research, and collaborate with other investigators, clinicians, and leaders to improve health outcomes and care delivery. Successful candidate(s) will be accountable for conceptualizing and designing research projects, leading, and collaborating on such projects, and disseminating research results through presentations and publication in peer-reviewed journals and conferences. Service on committees and participation in scientific peer-review processes are also expected. HealthPartners Institute Research Investigators are primarily supported through grants and contracts from external sources, including the National Institutes of Health (NIH), Centers for Disease Control and Prevention (CDC), and the Patient-Centered Outcomes Research Institute (PCORI). HealthPartners Institute is focused on improving health and well-being through research, education, and practice. Our Research Investigators are embedded in an integrated health system and our research draws on rich clinical data derived from a comprehensive, fully integrated state-of-the-art electronic medical and dental record and claims data from over a million HealthPartners patients and members. Required Qualifications: MD/DO or equivalent degree and clinical experience in geriatrics, neurology, or related discipline Current Minnesota Medical license or eligible for MN medical license, based on active medical license in another state and in good standing. Prior record leading research projects and independent scholarly publications in the peer-reviewed scientific literature Strong methodologic expertise Strong interpersonal skills Strong oral and written communication skills Preferred Qualifications: Master's degree in public health or similar formal training in research methodology Early to mid-career investigator with demonstrated potential to lead active portfolio of externally funded research. Demonstrated history of successful collaboration in interdisciplinary project teams 3+ years of health care or clinical trial research experience Experience working with electronic health records or other health care data. Experience writing research proposals. For more information on HealthPartners Institute, please visit ******************************************

HealthPartners Institute is seeking a full-time Physician Research Investigator (0.8 FTE - 1.0 FTE) with both clinical and research experience relevant to the study of chronic disease in adult populations. Areas of focus may include diabetes, cardiovascular disease, and other chronic diseases prevalent in adults. Eligible candidates may bring expertise in a range of study designs including observational or interventional studies. Candidates with prior experience in health services research, clinical decision support, or implementation science are encouraged to apply. Research Investigators at HealthPartners Institute may obtain or maintain external academic appointments. Eligible candidates are encouraged to practice part-time within the HealthPartners Medical group depending on practice interest and availability (up to 40% of Total FTE could be clinical work). At HealthPartners Institute, Researcher Investigators are expected to support and develop externally funded research programs, conduct nationally and internationally recognized scholarly clinical or health services research, and collaborate with other investigators, clinicians, and leaders to improve health outcomes and care delivery. Successful candidate(s) will be accountable for conceptualizing and designing research projects, leading, and collaborating on such projects, and disseminating research results through presentations and publications in peer-reviewed journals and conferences. Service on committees and participation in scientific peer-review processes are also expected. HealthPartners Institute Research Investigators are primarily supported through grants and contracts from external sources, including the National Institutes of Health (NIH), Centers for Disease Control and Prevention (CDC), and the Patient-Centered Outcomes Research Institute (PCORI). HealthPartners Institute is focused on improving health and well-being through research, education, and practice. Our Research Investigators are embedded in an integrated health system and our research draws on rich clinical data derived from comprehensive, fully integrated state-of-the-art electronic medical and dental record and claims data from over a million HealthPartners patients and members. In addition, HealthPartners Institute is a member of numerous research networks, including the Health Care Systems Research Network (HCSRN) and the Minnesota EHR Consortium, providing opportunities to conduct multisite and population-based studies. We offer a supportive, collegial work environment and mentoring for early and mid-career investigators. HealthPartners fosters an environment that is inclusive, encourages creative thinking, and celebrates diversity. We're committed to living our values of excellence, compassion, integrity, and partnership. If you feel your skills are a match for this role, we would love to hear from you and provide additional information about how we support our researchers. Required Qualifications: MD/DO or equivalent degree and clinical experience in internal medicine, family medicine, hospital medicine, preventive medicine, or a related discipline Early to mid-career investigator with demonstrated leadership skills and potential to lead active portfolio of externally funded research. Prior history as first author of scholarly peer-reviewed publications Experience authoring research proposals. Methodologic expertise in qualitative or quantitative approaches Strong people skills Strong oral and written communication skills Current Minnesota or Wisconsin Medical license or eligible for MN or WI medical license, based on active medical license in another state and in good standing. Preferred Qualifications: PhD or master's degree in public health or similar formal training in research methodology Demonstrated history of successful collaboration in interdisciplinary project teams 3+ years of health care research experience Experience working with electronic health records or other health care data. For more information on HealthPartners Institute, go to ******************************************

Language Requirement: No Korean language skills required This role focuses on conducting sensory evaluations to ensure product quality within the New Product Development (NPD) process. The position also involves supporting R&D budget control and administrative tasks. Key Responsibilities: Conduct sensory evaluations to assess food product attributes for NPD and product excellence management. Organize, train, and maintain sensory panels for accurate data collection. Analyze sensory data and provide insights to guide product development. Collaborate with Marketing and other teams to align sensory insights with product strategies. Stay updated on industry trends and sensory evaluation techniques. Communicate sensory findings to food scientists and stakeholders. Support R&D budget monitoring and administrative tasks. Research industry trends and competitors to ensure market competitiveness. Qualifications: Bachelors degree in Food Science or a related field. 3+ years of experience in sensory evaluation within the food industry. Experience in food product development is a plus. Excellent communication and organizational skills. Proficiency in MS Office. Ability to manage tasks independently with minimal supervision. Strong attention to detail and ability to handle confidential information.

We are a technology-led healthcare solutions provider. We are driven by our purpose to enable healthcare organizations to be future-ready. We offer accelerated, global growth opportunities for talent that's bold, industrious, and nimble. With Indegene, you gain a unique career experience that celebrates entrepreneurship and is guided by passion, innovation, collaboration, and empathy. To explore exciting opportunities at the convergence of healthcare and technology, check out ************************ Looking to jump-start your career? We understand how important the first few years of your career are, which create the foundation of your entire professional journey. At Indegene, we promise you a differentiated career experience. You will not only work at the exciting intersection of healthcare and technology but also will be mentored by some of the most brilliant minds in the industry. We are offering a global fast-track career where you can grow along with Indegene's high-speed growth. We are purpose-driven. We enable healthcare organizations to be future ready and our customer obsession is our driving force. We ensure that our customers achieve what they truly want. We are bold in our actions, nimble in our decision-making, and industrious in the way we work. Must Have * Review of promotional and medical communication materials (for various client products) and ensure the content in these materials is medically accurate, scientifically rigorous, truthful and balanced, relevant to product and therapy area, compliant to various pharma regulations and guidelines and is supported by authentic and up to date references. * Develop and update content for various medical materials, perform literature search to identify appropriate references to support creation/update of scientific content, track and audit assets for various purposes. * Develop and review content for various deliverables meeting quality requirements as per client satisfaction metrics, within assigned timelines and with guidance from the manager. The tasks will be carried out as per assigned processes, guidelines, and SOPs with help of tools and platforms specified by the client and the manager. * Responsible to follow the best practices in the department regarding - processes, communication (internal & external), project management, documentation, and technical requirements like - language, grammar, stylization, content search, summarizing, data conflicts and referencing. * Participate in assigned training programs and work on assignments as per requirement. * Participate in client calls as per project requirements. * Compliance to quality, confidentiality and security; Adhere and follow quality systems, processes and policies; Comply to training and specifications Your impact: About you: Prior work experience in medical review domain (1-2 years) is preferred for this position. Must have: * Education- MD/MDS/PhD (Post Doc (or experience)/MBBS with experience preferable). * Minimum 1 to 2 years of experience in pharmaceutical companies * Understanding of any specialty area of medicine (preferred) or an overall understanding of the medical field * Strong flair and passion for writing * Strong written and verbal communication/presentation skills * Passion for networking * Being up to date with the latest technical/scientific developments and relating them to various projects * Client-oriented attitude with focus on creating strong long-term relationships with clients and encouraging others to work toward this goal * Ability to assure timely completion of assignments * Skilled in problem identification and problem solving Good to have EQUAL OPPORTUNITY Indegene is proud to be an Equal Employment Employer and is committed to the culture of Inclusion and Diversity. We do not discriminate on the basis of race, religion, sex, colour, age, national origin, pregnancy, sexual orientation, physical ability, or any other characteristics. All employment decisions, from hiring to separation, will be based on business requirements, the candidate's merit and qualification. We are an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, national origin, gender identity, sexual orientation, disability status, protected veteran status, or any other characteristics.

We are a technology-led healthcare solutions provider. We are driven by our purpose to enable healthcare organizations to be future-ready. We offer accelerated, global growth opportunities for talent that's bold, industrious, and nimble. With Indegene, you gain a unique career experience that celebrates entrepreneurship and is guided by passion, innovation, collaboration, and empathy. To explore exciting opportunities at the convergence of healthcare and technology, check out ************************ Looking to jump-start your career? We understand how important the first few years of your career are, which create the foundation of your entire professional journey. At Indegene, we promise you a differentiated career experience. You will not only work at the exciting intersection of healthcare and technology but also will be mentored by some of the most brilliant minds in the industry. We are offering a global fast-track career where you can grow along with Indegene's high-speed growth. We are purpose-driven. We enable healthcare organizations to be future ready and our customer obsession is our driving force. We ensure that our customers achieve what they truly want. We are bold in our actions, nimble in our decision-making, and industrious in the way we work. Must Have Associate Scientific Writing-Content Job Description * Review of promotional and medical communication materials (for various client products) and ensure the content in these materials is medically accurate, scientifically rigorous, truthful and balanced, relevant to product and therapy area, compliant to various pharma regulations and guidelines and is supported by authentic and up to date references. * Develop and update content for various medical materials, perform literature search to identify appropriate references to support creation/update of scientific content, track and audit assets for various purposes. * Develop and review content for various deliverables meeting quality requirements as per client satisfaction metrics, within assigned timelines and with guidance from the manager. The tasks will be carried out as per assigned processes, guidelines, and SOPs with help of tools and platforms specified by the client and the manager. * Responsible to follow the best practices in the department regarding - processes, communication (internal & external), project management, documentation and technical requirements like - language, grammar, stylization, content search, summarizing, data conflicts and referencing. * Participate in assigned training programs and work on assignments as per requirement. * Participate in client calls as per project requirements. * Compliance to quality, confidentiality and security; Adhere and follow quality systems, processes and policies; Comply to training and specifications Must have: Nice to have: 1. Education- MD/MDS/PhD with Post Doc (or experience)/MBBS with experience 2. Minimum 2 to 4 years of experience in pharmaceutical companies 3. Understanding of any specialty area of medicine (preferred) or an overall understanding of the medical field 4. Strong flair and passion for writing 5. Strong written and verbal communication/presentation skills 6. Passion for networking 7. Being up to date with the latest technical/scientific developments and relating them to various projects 8. Client-oriented attitude with focus on creating strong long-term relationships with clients and encouraging others to work toward this goal 9. Ability to assure timely completion of assignments 10. Skilled in problem identification and problem solving Perks: (Mention if any, otherwise ignore) Good to have EQUAL OPPORTUNITY Indegene is proud to be an Equal Employment Employer and is committed to the culture of Inclusion and Diversity. We do not discriminate on the basis of race, religion, sex, colour, age, national origin, pregnancy, sexual orientation, physical ability, or any other characteristics. All employment decisions, from hiring to separation, will be based on business requirements, the candidate's merit and qualification. We are an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, national origin, gender identity, sexual orientation, disability status, protected veteran status, or any other characteristics.