Senior Associate Scientist jobs at Amgen - 1675 jobs

Career CategoryScientificJob DescriptionJoin Amgen's Mission of Serving Patients At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do. Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas -Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Principal Scientist - Inflammation Biomarkers What you will do Let's do this. Let's change the world. In this vital role you will help drive scientific and technical plans collaboratively with other members of the Precision Medicine function, as well as with members of the Amgen research and development community. You will successfully partner with cross-functional stakeholders to drive clinical biomarker innovation for clinical-stage assets in inflammatory diseases. The Principal Scientist will possess biomarker expertise in inflammatory and/or rare diseases such as arthritis, atopic dermatitis, inflammatory bowel disease, lupus, asthma, and/or autoimmune endocrinopathies. Key Responsibilities: Preparing clinical biomarker strategies, leading biomarker development, implementation, and execution for one or more programs Responsible for biomarker elements in clinical protocols, biomarker analysis plans, regulatory submissions, investigator meetings, advisory boards and publications Build productive relationships with team members and functional groups for integrating an aligned and prioritized clinical biomarker evidence plan that addresses clinical objectives and translational research Partner with cross-functional stakeholders including to drive biomarker innovation at product level Establish and implement biomarker studies and collaborations with academic laboratories/KOLs Interpret and communicate key clinical biomarker findings to cross-functional teams including Precision Medicine teams and leadership Responsible for robust clinical biomarker plans to deliver patient stratification/selection, pharmacodynamics, mechanism of action and resistance evidence from clinical trial samples What we expect of you We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a leader with these qualifications. Basic Qualifications: Doctorate degree in a bioscience or medical discipline and 2 years of industry experience Or Master's degree in a bioscience or medical discipline and 4 years of industry experience Or Bachelor's degree in a bioscience or medical discipline and 6 years of industry experience Or Associate's degree in a bioscience or medical discipline and 10 years of industry experience Or High school diploma / GED and 12 years of directly related industry experience Preferred Qualifications: PhD with 3 or more years pharmaceutical industry experience, developing biomarker strategies in a clinical development setting and/or in preclinical biomarker discovery/validation Knowledge and translational biomarker experience in inflammation is highly desirable Strong background in immunology, cell biology and genomics Clinical development experience working with cross-functional teams conducting clinical trials Experience in developing program-based strategies for pharmacodynamic, predictive, and exploratory biomarkers Experience implementing a broad array of biomarker platforms and technologies to support clinical-stage programs Demonstrated ability to establish and implement biomarker studies and collaborations with academic laboratories/KOLs Experience in assay development and qualification and analysis of clinical samples Experience managing biomarker assay outsourcing processes with external vendors and CROs Poise and professionalism with strong communication and influencing skills in a dynamic environment What you can expect of us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we'll support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies. Apply now and make a lasting impact with the Amgen team.careers.amgen.com In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. Sponsorship Sponsorship for this role is not guaranteed. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. . Salary Range 164,066.00 USD - 196,151.00 USD

Nimble is an AI robotics company building the autonomous supply chain to enable fast, efficient, and sustainable commerce. We're developing a general-purpose robot AI and a warehouse generalist superhumanoid robot, the first robot in the world capable of performing all core warehouse functions. We recently closed a $106M Series C at a $1B valuation, and we are continuing to grow our world‑class team. Mission: to empower and inspire mankind to accomplish legendary feats by inventing robots that liberate us from the menial. Vision: invent the Autonomous Supply Chain - everything from the inside of factories and warehouses to your front door - powered by industry‑generalist superhumanoids to deliver faster, more efficient, and more sustainable commerce. Our founding team comes from the AI labs at Stanford and Carnegie Mellon and our board of directors include famed robotics and AI legends including Marc Raibert (founder of Boston Dynamics), Sebastian Thrun (founder of GoogleX, Waymo; Stanford Professor and considered the father of autonomous vehicles) and Fei‑Fei Li (Chief Scientist of AI at Google and Director of Stanford's AI Lab). Join us and leave your mark on the future of robotics, AI, and global commerce. Why Join Nimble? At Nimble, we are committed to building legendary products, a legendary team, and a legendary legacy. Join us and become part of an ambitious, humble, and resourceful culture where your work will leave a lasting impact on the future of robotics and commerce. Nimble's Core Values: Be relentlessly resourceful - Challenge conventions and overcome obstacles. Be legendary - Be the very best and do work that inspires. Be humble - Prioritize growth, learning, and doing whatever is needed to further the mission. Be dependable - Take ownership and deliver with high agency. The Role Nimble is looking for an AI Robotics Research Scientist to help us advance our robotics moonshot by designing, developing, training, and implementing robotic foundation models, Vision‑Language‑Action Models, general‑purpose robotic AI models, and reinforcement learning algorithms controlling multi‑agent robot fleets. You will play a critical role in working with our all‑star cross‑functional team to build models with immediate applications for the world's biggest robotics opportunity. Responsibilities Develop and train diffusion policies, VLMs, multi‑agent deep RL policies and more Develop data collection pipelines Design data annotation and labeling Support implementation of models into production systems Qualifications P.h.D in Robotics or Computer Science Experience training deep learning models for robotic manipulation or mobility Experience working with real robotic hardware Experience training models in simulation and developing simulation environments Experience collecting custom datasets Experience training on open‑source datasets Strong track record of publishing papers and/or deploying real‑world applications Experience with system architecture, design and development Additional Requirements Must be able to work extended hours and weekends as needed Must be able to work in San Francisco $180,000 - $250,000 a year The above range is the salary range. This position will also receive generous equity for this position. Culture We embrace challenges and strive to make the impossible possible each day. We're not in this to do what's easy or to be mediocre. We want to create something legendary and leave our mark on the world. We're ambitious, we're gritty, we're humble and we're relentlessly resourceful in pursuit of our goals. If this sounds like you then you might be a great fit! Nimble Robotics, Inc. is an equal opportunity employer. We make all employment decisions based solely on merit. We provide equal employment opportunity to all applicants and employees without discrimination on the basis of race, color, religion, national origin, ancestry, disability, medical condition, genetic information, marital status, sex, gender, gender identity, gender expression, sexual orientation, age, military or veteran status, or any other characteristic protected by applicable state, federal or local laws. Nimble's Benefits Paid Time Off Enjoy the time you need to travel, rejuvenate, and connect with friends and family. Health Insurance Nimble provides medical, dental, and vision insurance through several premier plans and options to support you and your family. Paid Parental Leave Enjoy paid bonding time following a birth. Commuter Benefits Take the stress out of commuting with access to fully-paid parking spots. Referral Bonus Get a cash bonus for any friend or colleague that you refer to us that we end up hiring. 401k Contribute towards a 401k for retirement planning. Equity Be an owner in Nimble through our equity program. #J-18808-Ljbffr

A leading AI robotics firm based in San Francisco is seeking an AI Robotics Research Scientist. This role involves developing and training robotic AI models and working with an all-star team to tackle advanced robotics challenges. The ideal candidate will have a Ph.D. in Robotics or Computer Science and experience in deep learning and robotic hardware. A competitive salary range of $180,000 - $250,000 plus equity is offered, along with strong benefits that include paid time off, health insurance, and 401k contributions. #J-18808-Ljbffr

The Position: The Opportunity We are seeking an exceptional Principal Scientist (Group Leader) to join our world-class Antibody Engineering Department, where we discover and engineer life-changing antibody drugs through pioneering science and technology. The successful candidate will lead a scientific team to enhance existing platforms and develop novel technologies to expand our pipeline of antibody-based drugs across therapeutic areas. You will focus on these areas Contribute to research at the interface between technology and biology Define important therapeutic problems in collaboration with Genentech's therapeutic areas Drive innovation to solve them through antibody engineering Our new Scientist/Group Lead will help shape the future of our antibody drug capabilities and will be expected to present their research externally and publish in peer-reviewed journals. The hire will work collaboratively in a multi-disciplinary team environment to design, validate, and advance next generation biologics that address major unmet medical needs into clinical development. We are seeking highly motivated and self-driven candidates with a passion for innovation, creativity, and commitment to translational science and drug development. Who You Are PhD in a biological science, complemented by postdoctoral training or 4+ years recent equivalent antibody engineering in academia, biotechnology and/or pharma. We encourage applications from candidates with extensive prior experience as well as those coming directly from exemplary postdoc careers. The successful candidate will have demonstrated a sustained record of productivity and substantive scientific contributions as determined by consistent high-impact publications, patent inventorship, and/or external presentations. Candidates need to be team-oriented, collegial, and have strong interpersonal and communication skills. Preferred Ideal applicants will excel in protein engineering methodologies and be well-versed in biology. Experience with engineering bi- or multi-specific antibody/protein formats is preferred. Experience with structure-based protein analysis is a plus. Research experience with antibodies is preferred but is not essential. Relocation benefits are available for this job posting. The expected salary range for this position based on the primary location of California is $143,200 to $265,900. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below. Benefits #LI-KC2 Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company\'s policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants. #J-18808-Ljbffr

Job Category: Development Apply now Posted : November 5, 2025 Full-Time On-site Headquarters 9704 Medical Center Dr Rockville, MD 20850, USA MacroGenics is a leader in the discovery and development of innovative medicines that utilize our next generation antibody-based technologies. Our team of350+ dedicated individuals is advancing a pipeline of product candidates to treat patients with cancer. Our products and platforms have attracted multiple partnerships with leading pharmaceuticaland biotechnologycompanies around the globe. The Company considers its employees to be its most valuable asset and we are committed to providing opportunities for individuals to learn and grow as a means to further their professional development. MacroGenics' corporate culture promotes an atmosphere of innovation, open communication and teamwork where employees can see firsthand how they contribute to the success of the organization. Summary of Position The Principal Scientist is a technical and strategic leader responsible for method development, qualification, transfer, and lifecycle management of residual impurity assays for biopharmaceutical products including monoclonal antibodies (mAbs), bispecifics, and antibody-drug conjugates (ADCs). This individual thrives in a cross-functional, fast-paced, and collaborative environment, applying strong troubleshooting ability, scientific rigor, and a results-driven mindset to support programs from early development through commercialization. The role demands high accountability, proactive planning, and timely execution of deliverables. The Principal Scientist will supervise and mentor team members while serving as a subject matter expert in residual impurity testing across Biopharmaceutical Development (BPD) and CMC teams. Responsibilities and Job Duties: Lead the development of fit-for-purpose and robust residual impurity assays (e.g., HCP, DNA, Protein, Enzyme, Surfactant etc.) to support biologic product development and release. Provide technical leadership and hands‑on troubleshooting for analytical methods and instrumentation to resolve issues efficiently and maintain method robustness. Own and drive method lifecycle activities including development, qualification, transfer to QC, and support method validation aligned with ICH and regulatory expectations. Ensure on‑time delivery of analytical method development and testing support for process development, process characterization, analytical comparability, and CQA assessment efforts. Manage project timelines for impurity analysis and proactively communicate risks, progress, and mitigation strategies to stakeholders. Collaborate with CMC teams and Regulatory Affairs to develop residual impurity control strategies, specifications, and regulatory submissions. Manage vendor activities and oversee outsourced work including critical reagents, HCP coverage analysis, and CRO support. Lead implementation of new technologies and data‑driven approaches to improve throughput and sensitivity of impurity assays. Author and/or review SOPs, technical protocols and reports, and regulatory filings. Foster a high‑performance culture by coaching and mentoring scientists, promoting scientific excellence, accountability, and ownership. Present findings and strategies at internal cross‑functional meetings, technical forums, and external conferences. Participate in industry consortia on relevant topics and align internal strategies with industry practice. Qualifications Education & Experience Ph.D. in Biochemistry, Analytical Chemistry, Chemical Engineering, Pharmaceutical Sciences or related discipline with 6+ years of related industry experience, including 5+ years on residual impurity method development; or Master's degree with 12+ years of related industry experience; or Bachelor's degree with 14+ years of related industry experience 2+ years of people management experience with demonstrated ability to coach, develop and motivate high‑performing teams Prior experience in preparing analytical sections of IND, BLA and regulatory responses. Knowledge, Skills and Abilities Deep knowledge of residual impurity assay development (e.g. ELISA for residual protein, qPCR for DNA) Excellent troubleshooting and problem‑solving skills, with a systematic, data‑driven approach to resolving technical challenges Strong sense of accountability and ownership; consistently delivers to project goals and regulatory milestones Ability to manage multiple projects and priorities in a dynamic, cross‑functional environment Skilled in stakeholder management, with clear, proactive, and collaborative communication style Strong technical writing skills and attention to detail in documentation and data review Experience mentoring and developing scientific staff; promotes open communication and teamwork Solid understanding of CMC strategy, regulatory expectations, and phase appropriate analytical requirements Strong track record of independent troubleshooting, root cause investigation, and method remediation for impurity assays Proven success in delivering high‑quality results on time, even under changing priorities and compressed timelines. Demonstrated leadership and influence in cross‑functional matrix environments Preferred Qualifications Familiarity with potency assays, physiochemical assays and other characterization assays Knowledge in novel techniques on detecting and analyzing residual impurities Strong publication record and external scientific presence Experience in fostering partnership with clients through CDMO service Supervisory Responsibilities Yes. This role may supervise Associate Scientist and/or Scientist Additional Information The annual rate of pay for this position ranges from $129,500 - $197,500. For non‑exempt roles, and according to applicable regulations, there may be the possibility for overtime pay. This role is eligible for the Company's discretionary bonus and discretionary equity incentives. Eligible employees may participate in the Company's benefits programs, including medical / dental / vision / prescription coverage, employee wellness resources, 401(k) plan with employer match, access to an Employee Stock Purchase Plan, (ESPP), paid time off & paid parental leave benefits, and disability benefits. The annual pay rate range is described in good faith, and the Company believes is the range of possible compensation for this role at the time of this posting depending on the candidate's experience, qualifications, geographic location, and other factors permitted by law. The Company may ultimately pay more or less than the posted range, and this range may be modified in the future. No amount is considered to be wages or compensation until such amount is earned, vested, and determinable under the terms and conditions of the applicable policies and plans. The amount and availability of any bonus, commission, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole discretion unless and until paid and may be modified at the Company's sole discretion, consistent with the law. Statement MacroGenics is proud to be an equal opportunity employer. Employment selection and related decisions are made without regard to race, color, national origin, sex, gender identity, sexual orientation, religion, age, disability, protected veteran status, or any other characteristic protected by federal, state or local law. We are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the employment process, please email ******************** or call ************** and/or 711 for TTD/TTY service. Equal Opportunity Employer/Veterans/Disabled Equal Opportunity Employer. This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the Know Your Rights notice from the Department of Labor. We do not accept non‑solicited resumes or candidate submittals from search/recruiting agencies. #J-18808-Ljbffr

A leading healthcare institution in Boston seeks a Sr. Principal Scientist to oversee operations in a GMP lab, focusing on the production and quality control of radiopharmaceuticals. The ideal candidate will have extensive experience in aseptic operations, knowledge of QC methodologies, and a strong educational background in pharmaceuticals. This role requires meticulous documentation, adherence to GMP standards, and the ability to thrive in a fast-paced environment, contributing to pioneering advancements in patient care. #J-18808-Ljbffr

Aldea is a multi-modal foundational AI company reimagining the scaling laws of intelligence. We believe today's architectures create unnecessary bottlenecks for the evolution of software. Our mission is to build the next generation of foundational models that power a more expressive, contextual, and intelligent human-machine interface. The Role We are hiring a Foundational AI Research Scientist (LLMs) to pioneer next‑generation large‑language‑model architectures. Your work will focus on designing, prototyping, and empirically validating efficient transformer variants and attention mechanisms that can scale to production‑grade systems. You'll explore cutting‑edge ideas in efficient sequence modeling, architecture design, and distributed training-building the foundations for Aldea's next‑generation language models. This role is ideal for researchers who combine deep theoretical grounding with hands‑on systems experience. What You'll Do Research and prototype sub‑quadratic attention architectures to unlock efficient scaling of large language models. Design and evaluate efficient attention mechanisms including state‑space models (e.g., Mamba), linear attention variants, and sparse attention patterns. Lead pre‑training initiatives across a range of model scales from 1B to 100B+ parameters. Conduct rigorous experiments measuring the efficiency, performance, and scaling characteristics of novel architectures. Collaborate closely with product and engineering teams to integrate models into production systems. Stay at the forefront of foundational research and help shape Aldea's long‑term model roadmap. Minimum Qualifications Requires a Ph.D. in Computer Science, Engineering, or related field. 3+ years of relevant industry experience. Deep understanding of modern sequence modeling architectures including State Space Models (SSMs), Sparse Attention mechanisms, Mixture of Experts (MoE), and Linear Attention variants. Hands‑on experience pre‑training large language models across a range of scales (1B+ parameters). Expertise in PyTorch, Transformers, and large‑scale deep‑learning frameworks. Proven ability to design and evaluate complex research experiments. Demonstrated research impact through patents, deployed systems, or core‑model contributions. Nice to Have Experience with distributed training frameworks and multi‑node optimization. Knowledge of GPU acceleration, CUDA kernels, or Triton optimization. Publication record in top‑tier ML venues (NeurIPS, ICML, ICLR) focused on architecture research. Experience with model scaling laws and efficiency‑performance tradeoffs. Background in hybrid architectures combining attention with alternative sequence modeling approaches. Familiarity with training stability techniques for large‑scale pre‑training runs. Performance‑based bonus aligned with research and model milestones Equity participation Flexible Paid Time Off Comprehensive health, dental, and vision coverage Aldea is proud to be an equal‑opportunity employer. We are committed to building a diverse and inclusive culture that celebrates authenticity to win as one. We do not discriminate on the basis of race, religion, color, national origin, gender, gender identity, sexual orientation, age, marital status, disability, protected veteran status, citizenship or immigration status, or any other legally protected characteristics. Aldea uses E‑Verify to confirm employment eligibility in compliance with federal law. For more information please visit: ************************ Please note: We do not accept unsolicited resumes from recruiters or employment agencies and will not be responsible for any fees related to unsolicited resumes. #J-18808-Ljbffr

Headquartered in Miami, Aldea is a next-generation AI company focused on voice-based clinical and expert applications. Our flagship product, Advisor, uses proprietary AI to scale the impact of world-class minds across personal development, finance, parenting, relationships, and more-with faster, more cost-effective performance than traditional models. As a multidisciplinary team of builders, researchers, and product thinkers, we value clear thinking, sharp writing, and strong intuition for what people need. This is a rare opportunity to join an early-stage startup that will help define a new category. About Aldea Aldea is a multi-modal foundational AI company reimagining the scaling laws of intelligence. We believe today's architectures create unnecessary bottlenecks for the evolution of software. Our mission is to build the next generation of foundational models that power a more expressive, contextual, and intelligent human-machine interface. The Role We are seeking a Foundational AI Research Scientist (Speech) to advance the frontier of speech understanding and generation. You will lead applied research in speech-to-text (STT), text-to-speech (TTS), and speech-to-speech modeling, designing architectures and training strategies that redefine fidelity, controllability, and efficiency in voice-based systems. This role blends deep research expertise with strong engineering intuition. You'll drive end-to-end experimentation-from model design and training-pipeline setup to empirical validation-and help translate breakthroughs into production-grade systems. What You'll Do Research and prototype novel architectures for STT, TTS, and speech-to-speech modeling. Design and execute experiments validating new methods for scalability, performance, and quality. Collaborate cross-functionally with engineering teams to integrate research into real-world products. Stay current with foundational research in speech processing and generative modeling. Minimum Qualifications Requires a Ph.D. in Computer Science, Engineering, or related field 3+ years of relevant industry experience Demonstrated experience in training or researching TTS, STT, or speech-to-speech models. Deep understanding of modern sequence modeling architectures including State Space Models (SSMs), Sparse Attention mechanisms, Mixture of Experts (MoE), and Linear Attention variants Proven experience with pre-training foundational models from scratch on large-scale datasets. Track record of working with massive multi-modal datasets (audio, text, and speech corpora at scale). Deep expertise in PyTorch, Transformers, and modern deep-learning frameworks. Ability to translate complex research ideas into high-performance, maintainable code. Evidence of research excellence through impactful technical contributions. Nice to Have Experience with voice-based AI applications or multi-speaker synthesis. Publication record in top-tier venues (ICML, NeurIPS, ICLR, ICASSP, Interspeech). Background in cross-lingual or multilingual speech systems. Experience with data curation, filtering, and quality assessment pipelines for speech data. Performance-based bonus aligned with research milestones Equity participation Comprehensive health, dental, and vision coverage #J-18808-Ljbffr

A biopharmaceutical company seeks a Principal Scientist to lead the development of residual impurity assays for biologic products. This role demands strong technical leadership, project management, and a collaborative spirit in a fast-paced environment. Candidates should hold a Ph.D. with over 6 years of relevant experience. The role offers significant support in both professional growth and performance-driven compensation. #J-18808-Ljbffr

Principal Scientist - Quality Control Lead, Small Molecules Job Description At Gilead, we're creating a healthier world for all people. For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer - working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world's biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead's team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we're looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. The Principal Scientist, Quality Control (QC) Lead will be responsible for the strategic oversight and operational execution of cGMP analytical testing in support of small molecule clinical development programs. The role provides leadership for assigned programs across a range of QC activities, ensuring that testing, documentation, and data integrity standards meet regulatory requirements and project deliverables. The ideal candidate will bring deep technical expertise in analytical chemistry and cGMP operations, a strong understanding of phase-appropriate quality control strategies and requirements, and the ability to collaborate cross-functionally to enable successful delivery of clinical supply and development milestones. Quality Control Leadership & Strategy Define, implement, and continuously improve the QC strategy for small molecule clinical development programs in alignment with overall CMC and quality objectives. Serve as the point of contact for overall QC activities including method validation and transfer, reference materials, specifications, cGMP release testing, stability strategy and testing, and supervision of testing at external contract testing laboratories. Develop and maintain phase-appropriate QC strategies and processes to support manufacturing and regulatory submissions. Responsible for the management and approval of specifications, collaborating cross-functionally to establish scientifically sound and phase-appropriate specifications aligned with analytical capability, process understanding, and clinical and regulatory expectations. Represent QC on cross-functional product development teams, providing technical input and direction for analytical and quality decisions. Identify and drive opportunities for improvement in QC testing, workflows, data management, and compliance processes. Proactively identify and elevate potential QC risks, and communicate QC activities, risks, and issues to relevant stakeholders. Analytical Testing & Documentation Oversee and ensure compliant execution of QC testing for raw materials, intermediates, drug substance, and drug product. Ensure timely creation, review, and approval of QC documentation including test methods, protocols, reports, CoAs, and quality records. Provide QC oversight to contract testing laboratories, coordinating testing activities for on‑time delivery and confirming compliance with cGMP and data integrity expectations. Direct and oversee timely resolution of QC testing related investigations with comprehensive root‑cause analysis, risk assessment, and effective CAPAs. Compliance & Regulatory Affairs Ensure QC operations comply with cGMP, FDA, EMA, ICH, and other applicable regulations. Drive excellence in data integrity, documentation practices, and traceability across QC activities. Serve as a QC subject matter expert to draft and review CMC sections and supporting documents for regulatory filings and response to questions (RTQs). Cross‑Functional Collaboration Partner closely with Analytical Development, Manufacturing, Quality Assurance, Regulatory, and Supply Chain to ensure seamless coordination of analytical strategy and QC testing support throughout the product lifecycle. Support technology transfer and method implementation at internal and external laboratories. Provide QC input into product development and regulatory submission documentation. Basic Qualifications PhD or PharmD in a related field with 5+ years of experience. Master's Degree with 8+ years of experience. Bachelor's Degree with 10+ years of experience. Associate's Degree with 12+ years of experience. High School Degree with 14+ years of experience. Preferred Qualifications 10+ years of hands‑on and leadership experience in small molecule pharmaceutical analytical testing and quality control. Prior experience establishing analytical specifications and authoring CMC sections of regulatory submissions. Deep understanding of regulatory and phase‑appropriate QC expectations for clinical development. Demonstrated experience managing testing activities at external testing laboratories. Excellent scientific judgement, communication, cross‑functional collaboration, and influencing skills. Demonstrated ability to organize, plan, and execute multiple tasks with flexibility for changing priorities and plans. Must think critically and creatively and be able to work independently to determine appropriate strategy and resources for resolution of problems. Knowledge of medical devices and combination products. Gilead Core Values Integrity (Doing What's Right) Inclusion (Encouraging Diversity) Teamwork (Working Together) Excellence (Being Your Best) Accountability (Taking Personal Responsibility) The salary range for this position is: $195,670.00 - $253,220.00. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock‑based long‑term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*. For additional benefits information, visit: ****************************************************************** * Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans. Equal Employment Opportunity Gilead Sciences Inc. is committed to providing equal employment opportunities to all employees and applicants for employment, and is dedicated to fostering an inclusive work environment comprised of diverse perspectives, backgrounds, and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, sex, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status and other prohibited grounds specified in applicable federal, state and local laws. Applicants who require accommodation in the job application process may contact ApplicantAccommodations@gilead.com for assistance. How to Apply Please apply via the Internal Career Opportunities portal in Workday. Job Details Job Requisition ID R0048430 Full Time Job Level: Associate Director Click below to return to the Gilead Careers site Click below to see a list of upcoming events Click below to return to the Kite, a Gilead company Careers site #J-18808-Ljbffr

A pioneering AI technology company in San Francisco seeks a Foundational AI Research Scientist (Speech) to advance speech understanding and generation. The role involves leading research in STT, TTS, and speech-to-speech modeling, requiring a Ph.D. and substantial experience in training foundational models. Candidates should possess deep expertise in modern sequence modeling architectures and a history of impactful research contributions. The company offers flexible paid time off and comprehensive health coverage. #J-18808-Ljbffr

A multi-modal foundational AI company is seeking a Foundational AI Research Scientist to lead research on large-language-model architectures. The role involves designing and validating new transformer variants and attention mechanisms for production systems. Ideal candidates will have a Ph.D. and 3+ years of industry experience in AI research, with deep knowledge of sequence modeling architectures and pre-training of large models. The position offers a competitive salary, flexible PTO, and comprehensive benefits. #J-18808-Ljbffr

A pioneering AI company based in San Francisco seeks a Foundational AI Research Scientist (Speech) to drive advancements in speech understanding and generation. This role requires a Ph.D. and extensive experience in TTS and STT systems. Responsibilities include prototyping architectures, executing validation experiments, and collaborating with engineering teams. The ideal candidate will have deep expertise in modern sequence modeling and a proven track record with large-scale datasets. A strong engineering intuition and the ability to translate complex ideas into maintainable code are essential. #J-18808-Ljbffr

United States - California - Foster City Process/Product Development & Operations Regular The Associate Director/ Principal Scientist , Cell Culture Process Development (Pivotal & Commercial), will be responsible for leading aspects of cell culture development including commercial process development and process characterization for multiple biologics programs during pivotal phases (phases II/III and post-launch). In addition, this role is also expected to lead projects for cell culture process technology development, platform process evolution, and to support cell culture-related regulatory documentation. Key Responsibilities Optimize and characterize cell culture processes to supply pivotal trials and enable commercialization for monoclonal antibodies, multi‑specifics, and novel modalities. Lead and/or support entire lifecycle of pivotal activities including process risk assessment, process characterization, preparation of all supporting documentation/reports toward BLA submission, provide support to ensure successful process performance qualifications (PPQ), and author relevant sections of BLA. Lead and/or support technology transfer and investigation activities in partnership with the global manufacturing sciences and technologies (MSAT) group. Design experiments and perform hands‑on cell culture operations in shake flasks, ambr15, ambr250, bench‑scale bioreactors, and novel cell culture platforms. May provide support to pilot plant operation for up to 500 L single‑use bioreactor. Perform statistical analyses and appropriate modeling to assess process parameter criticality, identify acceptable ranges, and contribute to integrated control strategy. Author and review GMP and non‑GMP technical documents (reports, regulatory submissions/responses, batch records, SOPs etc.), present in group/cross‑functional meetings. Participate and work cross‑functionally within and outside of biologics technical development to achieve common goals. Explore, develop, and implement novel cell culture technologies to meet business needs. Manage direct and indirect reports and mentor junior group members while working in a flexible and agile environment. Some travel may be required to support technology transfers and provide oversight at external manufacturing facilities. Adhere to department budget and all training, compliance and safety requirements. Remain current on trends and new technology advancements across the Biopharmaceutical industry. Hire, mentor and develop team members within the organization to help build and grow a world‑class biologics cell‑culture process development organization. Qualifications Ph.D. with 5+ years OR M.S. with 8+ years OR B.S. with 10+ in a relevant scientific discipline (biology, bioengineering, chemical engineering, biochemical engineering). Experience leading pivotal stage cell culture process development/characterization and implementation in GMP facilities. Experience in building high‑performing teams through strategic coaching and feedback. Hands‑on laboratory operations experience including shake flask, high‑throughput bioreactor, bench scale bioreactor, and pilot scale cultures. Excellent communication, technical writing, and presentation skills and aptitude for creative problem solving. Demonstrated ability to collaborate and influence cross‑functionally. Experience in cell culture media development, and/or employing modeling techniques for upstream process development and optimization is preferred. Experience in statistics, design‑of‑experiments, and data analysis (e.g. JMP, Spotfire). Working knowledge of lab automation, data management, data science, knowledge management and data protection. Experience with viral vaccines is a plus. Passion for inclusion: knowing the business value of diverse teams, modeling inclusion, and embedding the value of diversity in the way he/she/they work. #J-18808-Ljbffr

United States - California - Foster City Clinical Development & Clinical Operations Regular Gilead's mission is to discover, develop, and deliver therapies that will improve the lives of patients with life‑threatening illnesses worldwide. The Principal Scientist in Biologics Analytical Development (Pivotal and Commercial) will be responsible for leading analytical development activities encompassing analytical project leadership and development of analytical methods. Additionally, they will be responsible for ensuring that product quality targets and specifications are established for the projects they lead based on robust patient‑centric considerations throughout pivotal development. Through these activities they will play an instrumental role in ensuring successful regulatory filing strategies. Responsibilities Provide leadership to a group of analytical development scientists Mentor and guide scientists in their roles Set clear expectations and prioritization of work packages Manage workload and resources effectively Develop analytical control strategies for drug substance and drug product, ensuring patient‑centric considerations are incorporated Develop robust analytical methods for drug substance and drug product appropriate for pivotal and commercial programs Design and execution of scientifically sound and regulatory compliant method bridging strategies Serve as an author and reviewer of CMC sections in regulatory filings, and support interactions with health agencies Collaborate across Gilead Pharmaceutical Development & Manufacturing (PDM) and partner with Quality, Supply Chain, Manufacturing, CMC Regulatory Affairs, Clinical Development and Technical Development to ensure timely delivery and successful commercialization of the late‑stage Biologics portfolio Exhibit comprehensive knowledge of cGMP practices and requirements Act as a key member of the extended Analytical Development leadership team to shape late‑stage development strategies Demonstrate comprehensive knowledge in key analytical CMC strategic areas including CQAs, separations methods, method bridging, reference standard, comparability, and specifications Drive for the adoption of novel and state‑of‑the‑art analytical technologies and approaches Manage and mentor talent to help cultivate a world class Biologics AD organization Basic Qualifications Bachelor's Degree and Ten Years' Experience Masters' Degree and Eight Years' Experience PhD and Five Years' Experience Preferred Qualifications Ph.D. with 5+ years or M.S. with 9+ years or B.S. with a minimum of 11+ years in Analytical Chemistry or related fields of industrial experience in biologics analytical development. Extensive experience with analytical method development and control strategies of biologics products. Well versed in separation techniques (e.g. UHPLC, CE‑SDS, iCIEF, CEX) commonly used for biologics analytical development Subject matter expert in establishing comprehensive control strategies for biologics products Expertise in the development/qualification of various assays, including for purity and process related impurities Well versed in FDA and ICH guidelines relating to registration, quality, and compliance concerning drug substance and drug product. Proven track record in drafting regulatory documentation at all stages, including IND, BLA, and PAS filings. Demonstrated ability of building strong collaborations with other CMC functions. Leadership qualities of the successful candidate include the following: collaboration, building and developing high performing teams, accountability, cross‑functional engagement and influence, program management. Ability to build high performing teams and to set clear and measurable goals for staff and prioritize projects and resources. People Leader Accountabilities Create Inclusion - knowing the business value of diverse teams, modeling inclusion, and embedding the value of diversity in the way they manage their teams. Develop Talent - understand the skills, experience, aspirations and potential of their employees and coach them on current performance and future potential. They ensure employees are receiving the feedback and insight needed to grow, develop and realize their purpose. Empower Teams - connect the team to the organization by aligning goals, purpose, and organizational objectives, and holding them to account. They provide the support needed to remove barriers and connect their team to the broader ecosystem. #J-18808-Ljbffr

An innovative AI startup in San Francisco is looking for a Foundational AI Research Scientist to pioneer next-generation large-language-model architectures. Ideal candidates will have a deep understanding of sequence modeling architectures, expertise in PyTorch, and experience in pre-training large language models. Join a dynamic team to help shape the future of intelligent human-machine interfaces. #J-18808-Ljbffr

A leading biotech company in Foster City is searching for a Senior Scientist with extensive experience in analyzing omics data such as RNA-Seq and WES. The ideal candidate will have a PhD and 8+ years of experience in the pharmaceutical or biotech industry, strong statistics knowledge, and excellent communication skills. Responsibilities include synthesizing scientific questions into research efforts and empowering teams to achieve organizational objectives. Join a dynamic team that values diversity and supports professional growth. #J-18808-Ljbffr

A leading global healthcare firm in San Diego is seeking a highly motivated scientist to contribute to biotherapeutics development. The successful candidate will discover and engineer antibodies, oversee experiments, and utilize various molecular biology techniques. Applicants should have at least 6 years of relevant experience and a strong background in flow cytometry. This position offers competitive compensation ranging from $110,250 to $187,000 along with comprehensive benefits. #J-18808-Ljbffr

A global healthcare leader in San Diego seeks a highly motivated scientist to contribute to the discovery and development of biotherapeutics. The role involves discovering and optimizing antibodies, utilizing flow cytometry, and requires strong skills in molecular biology and biochemistry. Ideal candidates should have significant industry experience and be detail-oriented, with excellent communication skills. Competitive compensation and benefits include a flexible benefits package and bonus potential. #J-18808-Ljbffr