Senior Scientist jobs at Arrowhead Pharmaceuticals - 488 jobs

Aldea is a multi-modal foundational AI company reimagining the scaling laws of intelligence. We believe today's architectures create unnecessary bottlenecks for the evolution of software. Our mission is to build the next generation of foundational models that power a more expressive, contextual, and intelligent human-machine interface. The Role We are seeking a Foundational AI Research Scientist (Speech) to advance the frontier of speech understanding and generation. You will lead applied research in speech-to-text (STT), text-to-speech (TTS), and speech-to-speech modeling, designing architectures and training strategies that redefine fidelity, controllability, and efficiency in voice-based systems. This role blends deep research expertise with strong engineering intuition. You'll drive end-to-end experimentation-from model design and training-pipeline setup to empirical validation-and help translate breakthroughs into production-grade systems. What You'll Do Research and prototype novel architectures for STT, TTS, and speech-to-speech modeling. Design and execute experiments validating new methods for scalability, performance, and quality. Collaborate cross-functionally with engineering teams to integrate research into real-world products. Stay current with foundational research in speech processing and generative modeling. Minimum Qualifications Requires a Ph.D. in Computer Science, Engineering, or related field 3+ years of relevant industry experience Demonstrated experience in training or researching TTS, STT, or speech-to-speech models. Deep understanding of modern sequence modeling architectures including State Space Models (SSMs), Sparse Attention mechanisms, Mixture of Experts (MoE), and Linear Attention variants Proven experience with pre-training foundational models from scratch on large-scale datasets. Track record of working with massive multi-modal datasets (audio, text, and speech corpora at scale). Deep expertise in PyTorch, Transformers, and modern deep-learning frameworks. Ability to translate complex research ideas into high-performance, maintainable code. Evidence of research excellence through impactful technical contributions. Nice to Have Experience with voice-based AI applications or multi-speaker synthesis. Publication record in top-tier venues (ICML, NeurIPS, ICLR, ICASSP, Interspeech). Background in cross-lingual or multilingual speech systems. Experience with data curation, filtering, and quality assessment pipelines for speech data. Performance-based bonus aligned with research milestones Equity participation Comprehensive health, dental, and vision coverage Flexible paid time off Aldea is proud to be an equal-opportunity employer. We are committed to building a diverse and inclusive culture that celebrates authenticity to win as one. We do not discriminate on the basis of race, religion, color, national origin, gender, gender identity, sexual orientation, age, marital status, disability, protected veteran status, citizenship or immigration status, or any other legally protected characteristics. Aldea uses E-Verify to confirm employment eligibility in compliance with federal law. For more information please visit: ************************ Please note: We do not accept unsolicited resumes from recruiters or employment agencies and will not be responsible for any fees related to unsolicited resumes. #J-18808-Ljbffr

Headquartered in Miami, Aldea is a next-generation AI company focused on voice-based clinical and expert applications. Our flagship product, Advisor, uses proprietary AI to scale the impact of world-class minds across personal development, finance, parenting, relationships, and more-with faster, more cost-effective performance than traditional models. As a multidisciplinary team of builders, researchers, and product thinkers, we value clear thinking, sharp writing, and strong intuition for what people need. This is a rare opportunity to join an early-stage startup that will help define a new category. About Aldea Aldea is a multi-modal foundational AI company reimagining the scaling laws of intelligence. We believe today's architectures create unnecessary bottlenecks for the evolution of software. Our mission is to build the next generation of foundational models that power a more expressive, contextual, and intelligent human-machine interface. The Role We are hiring a Foundational AI Research Scientist (LLMs) to pioneer next-generation large-language-model architectures. Your work will focus on designing, prototyping, and empirically validating efficient transformer variants and attention mechanisms that can scale to production-grade systems. You'll explore cutting‑edge ideas in efficient sequence modeling, architecture design, and distributed training-building the foundations for Aldea's next‑generation language models. This role is ideal for researchers who combine deep theoretical grounding with hands‑on systems experience. What You'll Do Research and prototype sub‑quadratic attention architectures to unlock efficient scaling of large language models. Design and evaluate efficient attention mechanisms including state‑space models (e.g., Mamba), linear attention variants, and sparse attention patterns. Lead pre‑training initiatives across a range of model scales from 1B to 100B+ parameters. Conduct rigorous experiments measuring the efficiency, performance, and scaling characteristics of novel architectures. Collaborate closely with product and engineering teams to integrate models into production systems. Stay at the forefront of foundational research and help shape Aldea's long‑term model roadmap. Minimum Qualifications Requires a Ph.D. in Computer Science, Engineering, or related field. 3+ years of relevant industry experience. Deep understanding of modern sequence modeling architectures including State Space Models (SSMs), Sparse Attention mechanisms, Mixture of Experts (MoE), and Linear Attention variants. Hands‑on experience pre‑training large language models across a range of scales (1B+ parameters). Expertise in PyTorch, Transformers, and large‑scale deep‑learning frameworks. Proven ability to design and evaluate complex research experiments. Demonstrated research impact through patents, deployed systems, or core‑model contributions. Nice to Have Experience with distributed training frameworks and multi‑node optimization. Knowledge of GPU acceleration, CUDA kernels, or Triton optimization. Publication record in top‑tier ML venues (NeurIPS, ICML, ICLR) focused on architecture research. Experience with model scaling laws and efficiency‑performance tradeoffs. Background in hybrid architectures combining attention with alternative sequence modeling approaches. Familiarity with training stability techniques for large‑scale pre‑training runs. Performance‑based bonus aligned with research and model milestones Equity participation Flexible Paid Time Off Comprehensive health, dental, and vision coverage #J-18808-Ljbffr

Headquartered in Miami, Aldea is a next-generation AI company focused on voice-based clinical and expert applications. Our flagship product, Advisor, uses proprietary AI to scale the impact of world-class minds across personal development, finance, parenting, relationships, and more-with faster, more cost-effective performance than traditional models. As a multidisciplinary team of builders, researchers, and product thinkers, we value clear thinking, sharp writing, and strong intuition for what people need. This is a rare opportunity to join an early-stage startup that will help define a new category. About Aldea Aldea is a multi-modal foundational AI company reimagining the scaling laws of intelligence. We believe today's architectures create unnecessary bottlenecks for the evolution of software. Our mission is to build the next generation of foundational models that power a more expressive, contextual, and intelligent human-machine interface. The Role We are seeking a Foundational AI Research Scientist (Speech) to advance the frontier of speech understanding and generation. You will lead applied research in speech-to-text (STT), text-to-speech (TTS), and speech-to-speech modeling, designing architectures and training strategies that redefine fidelity, controllability, and efficiency in voice-based systems. This role blends deep research expertise with strong engineering intuition. You'll drive end-to-end experimentation-from model design and training-pipeline setup to empirical validation-and help translate breakthroughs into production-grade systems. What You'll Do Research and prototype novel architectures for STT, TTS, and speech-to-speech modeling. Design and execute experiments validating new methods for scalability, performance, and quality. Collaborate cross-functionally with engineering teams to integrate research into real-world products. Stay current with foundational research in speech processing and generative modeling. Minimum Qualifications Requires a Ph.D. in Computer Science, Engineering, or related field 3+ years of relevant industry experience Demonstrated experience in training or researching TTS, STT, or speech-to-speech models. Deep understanding of modern sequence modeling architectures including State Space Models (SSMs), Sparse Attention mechanisms, Mixture of Experts (MoE), and Linear Attention variants Proven experience with pre-training foundational models from scratch on large-scale datasets. Track record of working with massive multi-modal datasets (audio, text, and speech corpora at scale). Deep expertise in PyTorch, Transformers, and modern deep-learning frameworks. Ability to translate complex research ideas into high-performance, maintainable code. Evidence of research excellence through impactful technical contributions. Nice to Have Experience with voice-based AI applications or multi-speaker synthesis. Publication record in top-tier venues (ICML, NeurIPS, ICLR, ICASSP, Interspeech). Background in cross-lingual or multilingual speech systems. Experience with data curation, filtering, and quality assessment pipelines for speech data. Performance-based bonus aligned with research milestones Equity participation Comprehensive health, dental, and vision coverage #J-18808-Ljbffr

A pioneering AI technology company in San Francisco seeks a Foundational AI Research Scientist (Speech) to advance speech understanding and generation. The role involves leading research in STT, TTS, and speech-to-speech modeling, requiring a Ph.D. and substantial experience in training foundational models. Candidates should possess deep expertise in modern sequence modeling architectures and a history of impactful research contributions. The company offers flexible paid time off and comprehensive health coverage. #J-18808-Ljbffr

A pioneering AI company based in San Francisco seeks a Foundational AI Research Scientist (Speech) to drive advancements in speech understanding and generation. This role requires a Ph.D. and extensive experience in TTS and STT systems. Responsibilities include prototyping architectures, executing validation experiments, and collaborating with engineering teams. The ideal candidate will have deep expertise in modern sequence modeling and a proven track record with large-scale datasets. A strong engineering intuition and the ability to translate complex ideas into maintainable code are essential. #J-18808-Ljbffr

A multi-modal foundational AI company is seeking a Foundational AI Research Scientist to lead research on large-language-model architectures. The role involves designing and validating new transformer variants and attention mechanisms for production systems. Ideal candidates will have a Ph.D. and 3+ years of industry experience in AI research, with deep knowledge of sequence modeling architectures and pre-training of large models. The position offers a competitive salary, flexible PTO, and comprehensive benefits. #J-18808-Ljbffr

At Gilead, we're creating a healthier world for all people. For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer - working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world's biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead's team plays a critical role in the discovery and development of life‑changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we're looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description The Principal Scientist, Quality Control (QC) Lead will be responsible for the strategic oversight and operational execution of cGMP analytical testing in support of small molecule clinical development programs. The role provides leadership for assigned programs across a range of QC activities, ensuring that testing, documentation, and data integrity standards meet regulatory requirements and project deliverables. Key Responsibilities Define, implement, and continuously improve the QC strategy for small molecule clinical development programs in alignment with overall CMC and quality objectives. Serve as the point of contact for overall QC activities including method validation and transfer, reference materials, specifications, cGMP release testing, stability strategy and testing, and supervision of testing at external contract testing laboratories. Develop and maintain phase‑appropriate QC strategies and processes to support manufacturing and regulatory submissions. Manage and approve specifications, collaborating cross‑functionally to establish scientifically sound and phase‑appropriate specifications aligned with analytical capability, process understanding, and clinical and regulatory expectations. Represent QC on cross‑functional product development teams, providing technical input and direction for analytical and quality decisions. Identify and drive opportunities for improvement in QC testing, workflows, data management, and compliance processes. Proactively identify and elevate potential QC risks, and communicate QC activities, risks, and issues to relevant stakeholders. Oversee and ensure compliant execution of QC testing for raw materials, intermediates, drug substance, and drug product. Ensure timely creation, review, and approval of QC documentation including test methods, protocols, reports, CoAs, and quality records. Provide QC oversight to contract testing laboratories, coordinating testing activities for on‑time delivery and confirming compliance with cGMP and data integrity expectations. Direct and oversee timely resolution of QC testing related investigations with comprehensive root‑cause analysis, risk assessment, and effective CAPAs. Ensure QC operations comply with cGMP, FDA, EMA, ICH, and other applicable regulations. Drive excellence in data integrity, documentation practices, and traceability across QC activities. Serve as a QC subject‑matter expert to draft and review CMC sections and supporting documents for regulatory filings and responses to questions (RTQs). Partner closely with Analytical Development, Manufacturing, Quality Assurance, Regulatory, and Supply Chain to ensure seamless coordination of analytical strategy and QC testing support throughout the product lifecycle. Support technology transfer and method implementation at internal and external laboratories. Provide QC input into product development and regulatory submission documentation. Basic Qualifications PhD or PharmD in a related field with 5+ years of experience. Master's Degree with 8+ years of experience. Bachelor's Degree with 10+ years of experience. Associate's Degree with 12+ years of experience. High School Degree with 14+ years of experience. Preferred Qualifications 10+ years of hands‑on and leadership experience in small molecule pharmaceutical analytical testing and quality control. Prior experience establishing analytical specifications and authoring CMC sections of regulatory submissions. Deep understanding of regulatory and phase‑appropriate QC expectations for clinical development. Demonstrated experience managing testing activities at external testing laboratories. Excellent scientific judgment, communication, cross‑functional collaboration, and influencing skills. Demonstrated ability to organize, plan, and execute multiple tasks with flexibility for changing priorities and plans. Must think critically and creatively and be able to work independently to determine appropriate strategy and resources for resolution of problems. Knowledge of medical devices and combination products. Salary and Benefits The salary range for this position is $195,670.00 - $253,220.00. Compensation varies by experience, qualifications, and geography. The position may also be eligible for a discretionary annual bonus, stock‑based long‑term incentives, paid time off, and a benefits package including company‑sponsored medical, dental, vision, and life insurance plans.* * Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans. For additional benefits information, visit ****************************************************************** Equal Employment Opportunity Gilead Sciences Inc. is committed to providing equal employment opportunities to all employees and applicants for employment, and is dedicated to fostering an inclusive work environment comprised of diverse perspectives, backgrounds, and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, sex, age, sexual orientation, physical or mental disability, genetic information, gender identity and expression, veteran status, and other prohibited grounds specified in applicable federal, state, and local laws. #J-18808-Ljbffr

A leading biopharmaceutical company in Foster City is seeking a Principal Scientist for Quality Control in Microbiology. This full-time position involves overseeing microbiological operations critical to the success of clinical and commercial products. Ideal candidates will have over 10 years of experience and a strong background in GMP principles and microbiological testing. The role demands excellent problem-solving and communication skills, contributing to ensuring compliance with industry standards. #J-18808-Ljbffr

* Extensive hands-on experience in analyzing and interpreting RNA-Seq (bulk and single cell), WES, WGS, ATAC-Seq, CITE-Seq, and TCR-Seq data is required. The experience in analyzing other omics data (e.g., spatial transcriptome, Chip-Seq, MeRIP-seq, NanoString, multiplex qPCR, HT screening data sets) is a plus.* Strong statistics knowledge, such as probability theory, univariate and multi-variable analysis, unsupervised and supervised analysis, regression analysis, survival analysis, feature selection, and power analysis. Excellent oral and written communication skills. Demonstrated capability to synthesize scientific questions into a coherent research effort and efficiently communicate scientific findings across different functional teams and present analysis results to project review teams and senior leader committees. A proactive and self-motivated scientist with a strong work ethic and scientific rigor; ability to work in a dynamic environment and manage multiple projects in parallel and adapt to changing priorities. Demonstrated track record of producing high-quality scientific results as an individual contributor and a team member.* A PhD in bioinformatics, computational biology, biostatics, cancer genomics, or a related field with 8+ years of relevant work experience in pharmaceutical/biotech inudstry.* Excellent interpersonal and communication skills that foster collaboration and teamwork.* Good understanding of cancer biology, immunology, molecular and cell biology.* Proficiency in R, Python, Perl, JAVA, or C/C++ programming languages.* Proficiency in high performance computing and cloud computing environments. Outstanding track record of scientific and technical proficiency, evidenced by high quality publications in peer-reviewed journals.* Create Inclusion - knowing the business value of diverse teams, modeling inclusion, and embedding the value of diversity in the way they manage their teams.* Develop Talent - understand the skills, experience, aspirations, and potential of their employees and coach them on current performance and future potential. They ensure employees are receiving the feedback and insight needed to grow, develop, and realize their purpose.* Empower Teams - connect the team to the organization by aligning goals, purpose, and organizational objectives and holding them to account. They provide the support needed to remove barriers and connect their team to the broader ecosystem. #J-18808-Ljbffr

Gilead Sciences, Inc. is a biopharmaceutical company that has pursued and achieved breakthroughs in medicine for more than three decades, with the goal of creating a healthier world for all people. The company is committed to advancing innovative medicines to prevent and treat life-threatening diseases, including HIV, viral hepatitis, and cancer. Gilead operates in more than 35 countries worldwide, with headquarters in Foster City, California. Microbiology: The QC Microbiology Principal Scientist is vital role for the success of Clinical and Commercial Biologics and Small Molecule Quality Control . This individual provid e s support for strategic leadership and overs ight of daily microbiological operations . Responsibilities include managing clinical and commercial microbiological specification strategies ( for product, raw materials and critical reagents programs ) , analytical method validations, and the compendial review program. The role will contribute to monitoring QC test method execution and leading the microbiological lifecycle management of clinical/ commercial small molecules/ biologics API/ drug substances and drug products . Department : Global Quality Control - GQC-Biologics and Small Molecules Job Responsibilities : Experience with Biologics and/or Small Molecules Quality Control microbiology and extensive knowledge of industry best practices and trends. In-depth understanding and application of GMP principles, concepts, practices and standards in the US and internationally. Must be able to develop and improve complex concepts, techniques, and standards and new applications based on quality principles and theories. Must be able to develop solutions to complex problems, which require a high degree of ingenuity, creativity and innovativeness. Must be able to exercise judgment and independently determine and take appropriate action where precedent may not exist. Proven ability to work with senior management to develop and ensure the implementation of Company-wide long-term solutions. Demonstrated an ability to develop a vision for Quality Control functions and have shaped the capabilities of the function to fulfill that vision. Demonstrated the ability to influence process and outcomes across functions. Willing to support future laboratory work . Qualification s : 10+ Years experience with BS OR 8+ Years with MS OR 5+ years of experience and PhD in Microbiolo gy, Chemistry, Biochemistry or related field. 2 + years of relevant experience in a GMP Microbiology Lab environment, including knowledge of microbiological testing, experience with aseptic processing, including sterile liquid handling and manipulation, familiarity with microbiology laboratory instrumentation and environmental monitoring. Deep knowledge and experience in Biopharmaceutical or Pharmaceutical quality control. Stays ahead of shifting microbiological trends in industry. Must think critically and creatively and be able to work independently to determine appropriate resources for resolution of problems. Strong organizational and planning skills. Shows excellent verbal and written communication skills and collaborative interpersonal skills. Share: Job Requisition ID R0044329 Full Time/Part Time Full-Time Job Level Associate Director Click below to return to the Gilead Careers site Click below to see a list of upcoming events Click below to return to the Kite, a Gilead company Careers site #J-18808-Ljbffr

United States - California - Foster City Process/Product Development & Operations Regular The Associate Director/ Principal Scientist , Cell Culture Process Development (Pivotal & Commercial), will be responsible for leading aspects of cell culture development including commercial process development and process characterization for multiple biologics programs during pivotal phases (phases II/III and post-launch). In addition, this role is also expected to lead projects for cell culture process technology development, platform process evolution, and to support cell culture-related regulatory documentation. Key Responsibilities Optimize and characterize cell culture processes to supply pivotal trials and enable commercialization for monoclonal antibodies, multi‑specifics, and novel modalities. Lead and/or support entire lifecycle of pivotal activities including process risk assessment, process characterization, preparation of all supporting documentation/reports toward BLA submission, provide support to ensure successful process performance qualifications (PPQ), and author relevant sections of BLA. Lead and/or support technology transfer and investigation activities in partnership with the global manufacturing sciences and technologies (MSAT) group. Design experiments and perform hands‑on cell culture operations in shake flasks, ambr15, ambr250, bench‑scale bioreactors, and novel cell culture platforms. May provide support to pilot plant operation for up to 500 L single‑use bioreactor. Perform statistical analyses and appropriate modeling to assess process parameter criticality, identify acceptable ranges, and contribute to integrated control strategy. Author and review GMP and non‑GMP technical documents (reports, regulatory submissions/responses, batch records, SOPs etc.), present in group/cross‑functional meetings. Participate and work cross‑functionally within and outside of biologics technical development to achieve common goals. Explore, develop, and implement novel cell culture technologies to meet business needs. Manage direct and indirect reports and mentor junior group members while working in a flexible and agile environment. Some travel may be required to support technology transfers and provide oversight at external manufacturing facilities. Adhere to department budget and all training, compliance and safety requirements. Remain current on trends and new technology advancements across the Biopharmaceutical industry. Hire, mentor and develop team members within the organization to help build and grow a world‑class biologics cell‑culture process development organization. Qualifications Ph.D. with 5+ years OR M.S. with 8+ years OR B.S. with 10+ in a relevant scientific discipline (biology, bioengineering, chemical engineering, biochemical engineering). Experience leading pivotal stage cell culture process development/characterization and implementation in GMP facilities. Experience in building high‑performing teams through strategic coaching and feedback. Hands‑on laboratory operations experience including shake flask, high‑throughput bioreactor, bench scale bioreactor, and pilot scale cultures. Excellent communication, technical writing, and presentation skills and aptitude for creative problem solving. Demonstrated ability to collaborate and influence cross‑functionally. Experience in cell culture media development, and/or employing modeling techniques for upstream process development and optimization is preferred. Experience in statistics, design‑of‑experiments, and data analysis (e.g. JMP, Spotfire). Working knowledge of lab automation, data management, data science, knowledge management and data protection. Experience with viral vaccines is a plus. Passion for inclusion: knowing the business value of diverse teams, modeling inclusion, and embedding the value of diversity in the way he/she/they work. #J-18808-Ljbffr

Job Title: Scientist I Duration: 12 Months Interview process: Two Rounds (1st round - Hiring Manager; 2nd round panel) Working Model: On-site 5 days/week Requirements: ** Practical experience supporting preclinical PK/PD studies ** Ability to perform PK data analysis and interpret nonclinical study results ** Proficiency in data analysis, database entry, and database management ** Working knowledge of coding/scripting to automate workflows and streamline data handling ** Familiarity with bioanalytical techniques such as ELISA, FACS, and LC-MS ** Basic understanding of animal physiology and cell culture ** BS or MS degree in Biological and/or data science or similar

An innovative AI startup in San Francisco is looking for a Foundational AI Research Scientist to pioneer next-generation large-language-model architectures. Ideal candidates will have a deep understanding of sequence modeling architectures, expertise in PyTorch, and experience in pre-training large language models. Join a dynamic team to help shape the future of intelligent human-machine interfaces. #J-18808-Ljbffr

A leading biotech company in Foster City is searching for a Senior Scientist with extensive experience in analyzing omics data such as RNA-Seq and WES. The ideal candidate will have a PhD and 8+ years of experience in the pharmaceutical or biotech industry, strong statistics knowledge, and excellent communication skills. Responsibilities include synthesizing scientific questions into research efforts and empowering teams to achieve organizational objectives. Join a dynamic team that values diversity and supports professional growth. #J-18808-Ljbffr

A biotechnology company in San Diego is seeking a Senior Principal Scientist specializing in DMPK Translational PKPD Modeling. The role involves developing mechanistic PK/PD models, leading drug discovery project teams, and collaborating with diverse research disciplines. Candidates must hold a PhD in Biochemistry or related field and possess substantial industry experience in pharmacokinetics. The position offers a competitive salary range of $156,900 to $214,000 with additional benefits including bonuses, retirement plans, and comprehensive health coverage. #J-18808-Ljbffr

Principal Scientist, Statistical Genetics & AI page is loaded## Principal Scientist, Statistical Genetics & AIlocations: Palo Alto (HQ)posted on: Posted Yesterdayjob requisition id: 2026011With the world's largest database of more than eleven million genotyped customers, 23andMe is at the forefront of using human genetics to advance biomedical research and transform healthcare. We are looking for a Principal Scientist, Statistical Genetics, with extensive training and experience to join our highly productive, world-class research team. ****Who We Are****We are a group of individuals passionate about genetic discovery. 23andMe Research Institute is a nonprofit medical research organization that enables people everywhere to access their genetic information, learn about themselves, and participate in the world's largest crowdsourced research initiative. The Institute aims to be the world's most significant contributor to scientific advancement, uniting people with the common goal of improving health and deepening our understanding of DNA - the code of life.****What You'll Do****The Principal Scientist will lead a team of statistical geneticists and provide scientific expertise on creating and using insights from human genetic data for various applications, including therapeutic target discovery, medical record analysis, and phenotype prediction.In this unique hybrid role, you will be expected to build an independent research program, while simultaneously executing on existing partnerships and identifying opportunities for new collaborations. You must possess world-class expertise in statistical genetics and a strong familiarity with AI/machine learning methodologies to drive discoveries in human health.****What You'll Bring****You must have a deep understanding of statistical and/or population genetics, with a significant track record of scientific achievement that includes multiple years of experience leading development and implementation of novel methods and bioinformatics tools and executing independently developed ideas. These achievements should demonstrate your ability to balance scientific rigor with a pragmatic commitment to getting things done in the face of multiple competing priorities. You will also have a track record of collaboration with scientific thought leaders, and be expected to take an active role in engaging with external academic and industry scientists. Our team is very collaborative, and the ability to communicate ideas and results to other scientists and non-scientists in the context of business objectives is key. You should have a demonstrated ability to clearly and effectively communicate with a wide range of internal and external audiences, as well as experience building, mentoring, and leading teams of scientists.****Scientific Expertise:***** PhD in Statistics, Statistical Genetics, Population Genetics, Computational Biology, AI, Machine Learning, or related field with at least ten years of experience post-PhD.* Strong record of accomplishment, either through academic publications or successful industry achievements.* Deep expertise in human statistical genetics. Experience in biopharmaceutical applications or sequencing data are desirable.* Ability to work with senior scientific leadership to help represent the company at appropriate scientific, business, and other professional meetings.* Deep expertise in design of experiments and analysis of complex data.****Leadership Skills:***** Proven ability to mentor, train, and develop junior scientists.* Ability to lead directly and by influence, including strong problem solving, conflict resolution, and analytical skills.* Ability to communicate clearly and effectively.* Exceptional interpersonal, verbal and written communication skills. Demonstrated ability to communicate clearly and concisely with all stakeholders.23andMe, headquartered in California, is a leading consumer genetics and research company. The company's mission is to help people access, understand, and benefit from the human genome. 23andMe has pioneered direct access to genetic information as the only company with multiple FDA authorizations for genetic health risk reports. The company has created the world's largest crowdsourced platform for genetic research, with 80 percent of its customers electing to participate. 23andMe research participants consent to research conducted by 23andMe which is overseen by an independent third-party Institutional Review Board (IRB) regulated under the 'Common Rule' (45 CFR part 46). More information is available at *************************** 23andMe, we value a diverse, inclusive workforce and we provide equal employment opportunity for all applicants and employees. All qualified applicants for employment will be considered without regard to an individual's race, color, sex, gender identity, gender expression, religion, age, national origin or ancestry, citizenship, physical or mental disability, medical condition, family care status, marital status, domestic partner status, sexual orientation, genetic information, military or veteran status, or any other basis protected by federal, state or local laws. If you are unable to submit your application because of incompatible assistive technology or a disability, please contact us at accommodations-ext@23andme.com. 23andMe will reasonably accommodate qualified individuals with disabilities to the extent required by applicable law.Please note: 23andMe does not accept agency resumes and we are not responsible for any fees related to unsolicited resumes. Thank you.**Pay Transparency**23andMe takes a market-based approach to pay, and amounts will vary depending on your geographic location. The salary range reflected here is for a candidate based in the San Francisco Bay Area. The successful candidate's starting pay will be determined based on job-related skills, experience, qualifications, work location, and market conditions. These ranges may be modified in the future. San Francisco Bay Area Base Pay Range $220,000-$260,000 USD #J-18808-Ljbffr

A prominent genetics research organization in Palo Alto seeks a Principal Scientist in Statistical Genetics to lead a team in applying genetic data for therapeutic discoveries and medical data analysis. The role requires a PhD with extensive experience in statistical genetics, AI, and leadership in scientific research. Ideal candidates should have a strong publication record and excellent communication skills to engage with various stakeholders. Join this innovative team to drive significant contributions in human health. #J-18808-Ljbffr

A leading biopharmaceutical company in San Diego seeks a Sr. Engineer or Sr. Scientist for API Development. The role requires expertise in cell culture and process development within a cGMP environment. Candidates should possess a relevant degree alongside significant experience in cell culture techniques and regulatory compliance. The ideal candidate will be involved in cross-functional teams, ensuring efficient processes from pre-clinical to commercial phases. This position offers competitive compensation and an opportunity to contribute to impactful treatments. #J-18808-Ljbffr

Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing. Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates. Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need. The Position This position will involve assisting in the synthesis and subsequent purification steps of large scale oligonucleotides. The operator must comply with GLP/GMP protocols and be able to follow all association SOPs and work instructions when performing and documenting operations. Responsibilities Follow batch records, SOPs, and work instructions to detail Document all operations in batch records and logbooks Comply with GMP protocols Operate large scale oligonucleotide manufacturing equipment (i.e. oligonucleotide synthesizer, purification skid, tangential flow filtration system, lyophilizer, ChemGlass reactors, pH/conductivity meters, peristaltic pumps, etc.) Assist other chemists within the Manufacturing group during synthesis and purification of oligonucleotides including: Reagent solution preparation Mobile phase preparation Column Packing Fraction collection Perform oligonucleotide/intermediate analysis via LCMS Communicate with cross-functional groups such as Process Development, Analytical Development, Quality Control, Quality Assurance, etc. Maintain a clean work space Maintain safety by wearing required personal protective equipment Track and update raw material usage in D365 ERP software Act as production campaign lead Assist with new personnel training Requirements: Bachelor's degree in a scientific field OR appropriate work experience Entry level to 2 years experience in a similar position Good verbal and written communication skills Ability to work in a team environment Ability to pay attention to detail Preferred: Experience working in a GMP setting and controlled documentation Wisconsin pay range $63,000-$73,000 USD Arrowhead provides competitive salaries and an excellent benefit package. All applicants must have authorization to work in the US for a company. California Applicant Privacy Policy