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Become An Associate Principal Scientist

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Working As An Associate Principal Scientist

  • Getting Information
  • Analyzing Data or Information
  • Identifying Objects, Actions, and Events
  • Updating and Using Relevant Knowledge
  • Documenting/Recording Information
  • Mostly Sitting

  • $89,607

    Average Salary

What Does An Associate Principal Scientist Do At Merck

* May have overall responsibility for, or assist in, worldwide pharmacoepidemiologic planning and study recommendations for assigned Merck products in Respiratory, Immunology, or Cardiovascular therapy areas.
* Has lead responsibility or support responsibility for interaction with risk management subteams, value evidence subteams, clinical/regulatory subteams, and other areas of Merck Research Laboratories on epidemiologic matters related to product safety, risk management, post-marketing safety studies, post-authorization effectiveness studies, and regulatory activities.
* Has responsibility for the design, conduct, and analysis of epidemiologic research studies on assigned Merck products in Respiratory, Immunology, or Cardiovascular therapy areas.
* May present epidemiologic research plans or results to internal review and governance committees; to external agencies such as FDA (including advisory committees) or EMA and at scientific conferences.
* Maintains close working relationships with colleagues in Clinical Research, Regulatory, Outcomes Research, and Health Economics.
* Assists them in areas where knowledge of epidemiology is relevant.
* Contributes to Merck's prestige by maintaining recognition as an expert in his/her field; may publish independent scientific research in leading journals, participate in and present at scientific organizations and meetings, and serve as a peer reviewer for scientific journals

What Does An Associate Principal Scientist Do At Astrazeneca Pharmaceuticals LP

* Identify and develop patient selection and pharmacodynamic biomarkers for clinical studies based on the best available science and technologies
* Interrogate clinical samples to understand mechanism of action and key oncology/immuno-oncology pathway interactions and feedback mechanisms to guide rational drug combinations
* Evaluate and compare emerging technologies and analytical methods to identify those that generate the best data from precious clinical samples
* Generate disease linkage data to guide selection of tumor types and molecular segments and targeted patient populations
* Measure target engagement reliably and quantifiably to inform clinical decisions for selecting therapeutically relevant doses and schedules
* Work collaboratively with colleagues to develop and implement work plans and timelines

What Does An Associate Principal Scientist Do At Astrazeneca Pharmaceuticals LP

* Contributing to the development and implementation of new strategies for Safety and ADME Translational Sciences (SATS)
* Advancing the science of systems pharmacology in translational safety and ADME
* Analysing outcomes of toxicology studies and developing modelling platforms to impact project decision-making
* Evaluating and interpreting data to prepare for internal governance bodies
* Working in appropriate internal and external forums to champion the use of modelling and simulation in translational safety and ADME
* Identifying opportunities and driving collaborations with internal and external stakeholders

What Does An Associate Principal Scientist Do At Merck

* Develops, coordinates, and provides biostatistical leadership and support for related drug/vaccine projects in Late Development Statistics.
* Interacts with Clinical, Regulatory, Statistical Programming, Data Management, and other Merck Research Laboratories Scientists in designing and analyzing clinical trials, and in coordinating the statistical activities for clinical drug/vaccine projects.
* May interact with Contract Research Organization (CRO).
* This position may serve as a statistical lead in project teams.
* The incumbent may initially work in a specific disease area.
* Primary activities:
* Serves as statistical representative and lead in the cross-functional teams for the strategic planning and execution for product development
* Is involved in clinical development planning to ensure that study designs are consistent with program objectives and meet worldwide regulatory and marketing needs.
* Independently identifies and anticipates technical or other potential problems arising in the design, conduct, and analysis of clinical trials, proposes solutions and carries them out.
* Develops individual protocols and data analysis plans and independently determines appropriate statistical methodology for analysis.
* Participates in database design meetings to ensure that the data evaluated are in high quality and satisfy analysis requirements.
* Collaborates with the statistical programming staff to ensure that all programs meet analysis requirements, internal standard operating procedures, and external regulatory requirements
* Evaluates appropriateness of available software for planned analyses and ascertains needs for potential program development of novel statistical methodology.
* Analyzes data and interprets results from clinical trials to meet objectives of the study protocol.
* Independently applies and implements basic and complex statistical techniques to these analyses.
* Prepares oral and written reports to effectively communicate results of clinical trials to the project team, Merck Management, regulatory agencies, or individual investigators.
* Provides responses to queries relating to study design, analysis, and interpretation posed by the clinical monitors, regulatory agencies, and/or investigators.
* Is responsible for planning and ensuring the accuracy of Statistical Review Aids submitted to regulatory agencies.
* Participates with management in discussions with corresponding scientific personnel at regulatory agencies and with investigators concerning proposed or ongoing studies.
* Involved in research activities for innovative statistical methods and applications in clinical trial development.
* Mentors and guides junior staff in functional activities

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How To Become An Associate Principal Scientist

Medical scientists typically have a Ph.D., usually in biology or a related life science. Some medical scientists get a medical degree instead of a Ph.D., but prefer doing research to practicing as a physician.

Education

Students planning careers as medical scientists typically pursue a bachelor’s degree in biology, chemistry, or a related field. Undergraduate students benefit from taking a broad range of classes, including life sciences, physical sciences, and math. Students also typically take courses that develop communication and writing skills, because they must learn to write grants effectively and publish research findings.

After students have completed their undergraduate studies, they typically enter Ph.D. programs. Dual-degree programs are available that pair a Ph.D. with a range of specialized medical degrees. A few degree programs that are commonly paired with Ph.D. studies are Medical Doctor (M.D.), Doctor of Dental Surgery (D.D.S.), Doctor of Dental Medicine (D.M.D.), and Doctor of Osteopathic Medicine (D.O.). Whereas Ph.D. studies focus on research methods, such as project design and data interpretation, students in dual-degree programs learn both the clinical skills needed to be a physician and the research skills needed to be a scientist.

Graduate programs emphasize both laboratory work and original research. These programs offer prospective medical scientists the opportunity to develop their experiments and, sometimes, to supervise undergraduates. Ph.D. programs culminate in a thesis that the candidate presents before a committee of professors. Students may specialize in a particular field, such as gerontology, neurology, or cancer.

Those who go to medical school spend most of the first 2 years in labs and classrooms, taking courses such as anatomy, biochemistry, physiology, pharmacology, psychology, microbiology, pathology, medical ethics, and medical law. They also learn how to record medical histories, examine patients, and diagnose illnesses. They may be required to participate in residency programs, meeting the same requirements that physicians and surgeons have to fulfill.

Medical scientists often continue their education with postdoctoral work. Postdoctoral work provides additional and more independent lab experience, including experience in specific processes and techniques such as gene splicing, which is transferable to other research projects.

Licenses, Certifications, and Registrations

Medical scientists primarily conduct research and typically do not need licenses or certifications. However, those who administer drugs, gene therapy, or otherwise practice medicine on patients in clinical trials or a private practice need a license to practice as a physician.

Important Qualities

Communication skills. Communication is critical, because medical scientists must be able to explain their conclusions. In addition, medical scientists write grant proposals, because grants often are required to fund their research.

Critical-thinking skills. Medical scientists must use their expertise to determine the best method for solving a specific research question.

Data-analysis skills. Medical scientists use statistical techniques, so that they can properly quantify and analyze health research questions.

Decisionmaking skills. Medical scientists must determine what research questions to ask, how best to investigate the questions, and what data will best answer the questions.

Observation skills. Medical scientists conduct experiments that require precise observation of samples and other health data. Any mistake could lead to inconclusive or misleading results.

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Associate Principal Scientist jobs

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Associate Principal Scientist Demographic

Gender

  • Male

    53.8%
  • Female

    30.8%
  • Unknown

    15.4%

Ethnicity

  • White

    59.3%
  • Asian

    29.8%
  • Hispanic or Latino

    6.9%
  • Unknown

    3.4%
  • Black or African American

    0.7%
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Languages Spoken

  • Chinese

    16.7%
  • French

    16.7%
  • Fijian

    16.7%
  • Spanish

    16.7%
  • Russian

    16.7%
  • Italian

    16.7%
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Associate Principal Scientist

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Associate Principal Scientist Typical Career Paths

Associate Principal Scientist Education

Associate Principal Scientist

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Real Associate Principal Scientist Salaries

Job Title Company Location Start Date Salary
Associate Principal Scientist SCHRÖDinger, Inc. New York, NY Oct 01, 2014 $125,000
Associate Principal Scientist Merck Sharp & Dohme Corp. Rahway, NJ Jun 14, 2016 $116,688
Associate Principal Scientist SCHRÖDinger, Inc. New York, NY Aug 26, 2015 $116,000
Associate Principal Scientist Kraft Foods Group, Inc. Glenview, IL Sep 01, 2013 $113,332
Associate Principal Scientist Biostatistics Merck Sharp & Dohme Corp. Rahway, NJ Nov 14, 2016 $113,256
Associate Principal Scientist Merck Sharp & Dohme Corp. North Wales, PA Aug 15, 2013 $107,474
Associate Principal Scientist, Bioprocess Merck Sharp & Dohme Corp. Kenilworth, NJ Aug 29, 2016 $101,088
R&D Associate Principal Scientist QTG Development, Inc. Valhalla, NY Aug 16, 2016 $100,000
R&D Associate Principal Scientist Pepsico, Inc. Valhalla, NY Jul 13, 2016 $100,000
Associate Principal Scientist Chemistry Merck Sharp & Dohme Corp. Boston, MA Nov 18, 2013 $99,362
Associate Principal Scientist Chemistry Merck Sharp & Dohme Corp. Boston, MA Oct 01, 2013 $99,362
Associate Principal Scientist Merck & Co., Inc. Summit, NJ Jun 07, 2011 $99,320
Associate Principal Scientist Kraft Foods Global, Inc. East Hanover, NJ Sep 01, 2011 $97,412
Associate Principal Scientist Merck Sharp & Dohme Corp. Lebanon, NH Jun 01, 2013 $95,909
Associate Principal Scientist Pepsico, Inc. NY Aug 26, 2016 $93,500
Associate Principal Scientist, Pharmacokinetics Merck Sharp & Dohme Corp Kenilworth, NJ Jul 15, 2015 $93,267
Associate Principal Scientist, BIO & Vaccine Formulation Merck Sharp & Dohme Corp. Kenilworth, NJ Sep 07, 2015 $93,267
Associate Principal Scientist, BIO & Vaccine Formulation Merck Sharp & Dohme Corp. Kenilworth, NJ Jul 09, 2015 $93,267
Associate Principal Scientist, Pharmacokinetics Merck Sharp & Dohme Corp. Kenilworth, NJ Jul 31, 2013 $89,419
Associate Principal Scientist, BIO & Vaccince Form Merck Sharp & Dohme Corp. Kenilworth, NJ Jul 10, 2014 $89,419
Associate Principal Scientist, BIO & Vaccine Formu Merck Sharp & Dohme Corp. Kenilworth, NJ Jul 31, 2013 $89,419
Associate Principal Scientist-Pharmacokinetics Merck Sharp & Dohme Corp Kenilworth, NJ Mar 17, 2015 $89,419
Associate Principal Scientist-Biostatistics Merck Sharp & Dohme Corp. North Wales, PA Aug 15, 2014 $88,795
Associate Principal Scientist Biostatistics Merck Sharp & Dohme Corp. North Wales, PA Sep 01, 2014 $88,795
R&D Associate Principal Scientist Pepsico, Inc. Valhalla, NY May 18, 2014 $87,600

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Top Skills for An Associate Principal Scientist

AnalyticalMethodsDiscoveryMethodDevelopmentSafetyCrosProteinTargetsMedicinalChemistryMerckOncologyProductDevelopmentSmallMoleculeHplcGLPBiologyLc-Ms/MsFDAINDCMCDrugCandidatesAssayDevelopment

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Top Associate Principal Scientist Skills

  1. Analytical Methods
  2. Discovery
  3. Method Development
You can check out examples of real life uses of top skills on resumes here:
  • Participated in integration processes (post-merger activities) for the alignment of discovery and development activities to company priorities.
  • Provided global training to teams abroad and assisted them in setting up instrument and method development.
  • Conduct required monthly safety inspections.
  • Demonstrated leadership in cross-functional and global teams.
  • Established a deal flow between Merck and the Boston Angel community, with primary focus on Boston Harbor Angels.

Top Associate Principal Scientist Employers

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Associate Principal Scientist Videos

Pam Moran & Ira Socol: Leading for Radical Openness

Careers in Public Health Panel (2014)

High-Throughput Screening of GPCRs for Drug Discovery Applications - Recorded Webinar

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