Associate research scientist job description

At FibroGen, we approach our work each day with deep enthusiasm and the highest ethical standards, working with a passion to redefine what is possible in improving and saving the lives of patients. We value collaboration, extraordinary talent, and innovative thinking. We are motivated, curious, and passionate thinkers who believe in pushing scientific boundaries and are proud of our leadership and pioneering contributions to high-quality science. We have developed the first-in-class Hypoxia Inducible Factor - Prolyl Hydroxylase Inhibitor for the treatment of anemia of Chronic Kidney Disease and are working on other groundbreaking treatments for diseases with high unmet needs.
Scientist, Medicinal Chemistry

Responsibilities:
Independently design and synthesize compounds based off individual and team hypotheses Utilize novel synthetic methodologies and technologies without much supervision and provide recommendations on laboratory equipment as needed Carry out multi-step syntheses of small molecules with consistently high productivity Analyze and interpret data, solve synthetic challenges, and suggest follow-up experiments Collaborate with peers across departments and effectively communicate results conclusions in team and department meetings Maintain a laboratory notebook, contribute to patents, reports and scientific publications Adhere to FibroGen's laboratory safety policies and practices

Requirements:
BSc or MSc level with 3+ years industry experience Extensive knowledge of modern organic synthetic methods Excellence in common purification and analytical techniques Outstanding problem solving and communication skills

FibroGen is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender identity/expression, creed, national origin/ancestry, age, alienage or citizenship, status, age, sex, sexual orientation, marital or domestic/civil partnership status, disability, veteran status, genetic information, or any other basis protected by law.FibroGen will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of the San Francisco Fair Chance Ordinance.

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Notice to Recruiters and Search Firms
FibroGen makes every effort to source and hire its staff through direct recruitment methods. Employment opportunities at FibroGen are managed by our internal human resources team. Please do not contact hiring managers or other FibroGen employees.

FibroGen does not accept unsolicited resumes from any source other than from the candidates themselves. FibroGen does not accept unsolicited communications from external recruiters. If there is a specific business need, a human resources team member will contact external recruiters directly.

An agency or independent recruiter must have a current, signed agreement and a work order for a specific position with FibroGen before presenting candidates and must be presented to human resources. Submission of unsolicited resumes without a signed agreement and an applicable work order will not create an obligation on the part of FibroGen to pay a fee of any kind.

Research Chemist performing identification and quantitation of compounds. Perform studies supporting chemical characterization of materials to ensure safety and biocompatibility of materials for medical devices. Analytical method development and validation to support materials characterization of medical device components and solutions.
Responsibilities

Conduct drug container and medical device material evaluations studying the extractable/leachable compounds that can partition from the device material into fluids that are infused/transfused. Conduct other analytical and product testing for product support and for new product development. Independently generate study designs/protocols, write and distribute final reports. Occasionally will work with samples that include human blood and blood components using procedural controls and personal protective equipment. Assist in managing a laboratory testing capability that provides comprehensive chemical evaluation of materials for use in medical devices. Provide support for laboratory daily operations, calibrations and supplies.Provide technical input/content for analytical method development and review.Technical expert in the use and operation of HPLC, UPLC, GC chromatography techniques and instrumentation.Review laboratory documentation and results produced by colleagues.Provide oversight and training support to other chemists.

This job position within the Business Unit - Transfusion and Cell Technologies (BU-TCT) of Fresenius Kabi USA hereby commits itself to protect any persons working under its control from work related hazards to health and safety as well as to protect the environment as the basis of life. This includes the prevention of diseases, incidents and pollution as well as the responsible and sustainable use of resources. Our aim is to enhance our performance in the area of occupational and environmental safety, and to fulfill compliance obligations. To achieve this target, we implement and continuously improve the integrated management system according to OHSAS 18001 and ISO 14001.

Requirements
Requires working knowledge of laboratory analytical chemistry including classical techniques and advanced instrument systems.Requires significant experience (5-10 years) with the modern analytical tools and techniques of medical device and pharmaceutical product development. Must be experienced with gas chromatography (GC) and liquid chromatography (LC) equipped with mass spectrometry detectors, and elemental (atomic) spectroscopy (ICP or AA).Significant experience with (5-10 years) laboratory instrumental techniques, method development, method validation and system validation.Must have solid experience with chromatography/mass spectrometry including use of advanced data processing systems.A solid study director with total accountability for scientific study design, study execution, issue resolution and completion through audit.Strong written and verbal communication skills in prior roles Must have experience with FDA regulated laboratory environment of drug and medical device industries including GMP/GLP/GDP operations.Must be able to routinely perform analytical laboratory testing while also demonstrating critical thinking including study design, interpretation of complex data sets, propose next steps for investigations based on newly acquired data. Must have adequate structural chemistry knowledge to facilitate interpretation of mass spectral data.Advanced degree in chemistry is required. PhD in chemistry or a related discipline is preferred; alternatively, a Master's degree in Chemistry with specific and relevant experience in the areas defined under responsibilities and qualifications will be considered.

Additional Information

We offer an excellent salary and benefits package including medical, dental and vision coverage, as well as life insurance, disability, 401K with company match, and wellness program.

Fresenius Kabi is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, citizenship, immigration status, disabilities, or protected veteran status.

**Kelly Services is actively recruiting for a Direct Hire opportunity in** **San Diego** **, CA for an** **Associate Research** **Scientist** **, Pharmacology** **.**

We are looking for a talented Associate Research Scientist, Pharmacology a biopharmaceutical company focused on the discovery and development of novel RNA-based therapeutics for intractable diseases. We are currently seeking a talented, highly motivated, and independent research scientist to join our pharmacology/drug discovery group. The successful candidate is expected to execute in vivo, ex vivo and in vitro studies to evaluate new drug targets, novel drug candidates and treatment modalities to address unmet medical needs.
Salary: $79k

Major Job Functions

+ Propose research ideas; design and execute experiments independently

+ Develop and implement animal models to facilitate different research projects.

+ Establish and execute in vitro assays.

+ Accurately and precisely record experimental data, analyze the data, and maintain study notes/records timely

+ Present research progress to cross-functional groups/project teams.

Education and/or Experience

+ B.S, M.Sc with 2 years' experience in drug discovery.

+ Proficiency and hands-on experience in in vitro assay development and in vivo animal modeling

+ Knowledge of computer software and Microsoft applications (Word, Excel, PowerPoint, Graphpad Prism)

+ High motivation, independence, and ability to thinking critically and creatively to solve problems

+ Experience with nucleic acid-based drugs is a plus

***Level of the position is flexible and commensurate based on candidate's experience

**APPLY NOW!**

**You should know:** Your safety matters! Vaccination against COVID-19 may be a requirement for this job in compliance with current client and governmental policies. A Kelly recruiter will confirm and share more details with you during the interview process.

**Why Kelly** ** ** **Science & Clinical?**

Kelly Science & Clinical is your connection to premier scientific and clinical companies looking to hire industry experts just like you. Our team creates expert talent solutions to solve the world's most critical challenges. Every day, we match science professionals with dream jobs that fit their skills, interests, and career goals-it's the way we think job searching should be. Nearly 100 percent of our science recruiters have a professional background and education in science, so we know a thing or two about the science market and how to get your expertise noticed.

**About Kelly** ** **

At Kelly, we're always thinking about what's next and advising job seekers on new ways of working to reach their full potential. In fact, we're a leading advocate for temporary/nontraditional workstyles, because we believe they allow flexibility and tremendous growth opportunities that enable a better way to work and live (plus, did we mention we provide a ton of benefits ?). Connecting great people with great companies is what we do best, and our employment opportunities span a wide variety of workstyles, skill levels, and industries around the world.

Kelly Services is proud to be an Equal Employment Opportunity and Affirmative Action employer. We welcome, value, and embrace diversity at all levels and are committed to building a team that is inclusive of a variety of backgrounds, communities, perspectives, and abilities. At Kelly, we believe that the more inclusive we are, the better services we can provide. Requests for accommodation related to our application process can be directed to Kelly's Human Resource Knowledge Center.
Kelly complies with the requirements of California's state and local Fair Chance laws. A conviction does not automatically bar individuals from employment.