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  • Principal Scientist (Residual Impurities)

    MacRogenics, Inc. 4.8company rating

    Associate scientist job in Rockville, MD

    Job Category: Development Apply now Posted : November 5, 2025 Full-Time On-site Headquarters 9704 Medical Center Dr Rockville, MD 20850, USA MacroGenics is a leader in the discovery and development of innovative medicines that utilize our next generation antibody-based technologies. Our team of350+ dedicated individuals is advancing a pipeline of product candidates to treat patients with cancer. Our products and platforms have attracted multiple partnerships with leading pharmaceuticaland biotechnologycompanies around the globe. The Company considers its employees to be its most valuable asset and we are committed to providing opportunities for individuals to learn and grow as a means to further their professional development. MacroGenics' corporate culture promotes an atmosphere of innovation, open communication and teamwork where employees can see firsthand how they contribute to the success of the organization. Summary of Position The Principal Scientist is a technical and strategic leader responsible for method development, qualification, transfer, and lifecycle management of residual impurity assays for biopharmaceutical products including monoclonal antibodies (mAbs), bispecifics, and antibody-drug conjugates (ADCs). This individual thrives in a cross-functional, fast-paced, and collaborative environment, applying strong troubleshooting ability, scientific rigor, and a results-driven mindset to support programs from early development through commercialization. The role demands high accountability, proactive planning, and timely execution of deliverables. The Principal Scientist will supervise and mentor team members while serving as a subject matter expert in residual impurity testing across Biopharmaceutical Development (BPD) and CMC teams. Responsibilities and Job Duties: Lead the development of fit-for-purpose and robust residual impurity assays (e.g., HCP, DNA, Protein, Enzyme, Surfactant etc.) to support biologic product development and release. Provide technical leadership and hands‑on troubleshooting for analytical methods and instrumentation to resolve issues efficiently and maintain method robustness. Own and drive method lifecycle activities including development, qualification, transfer to QC, and support method validation aligned with ICH and regulatory expectations. Ensure on‑time delivery of analytical method development and testing support for process development, process characterization, analytical comparability, and CQA assessment efforts. Manage project timelines for impurity analysis and proactively communicate risks, progress, and mitigation strategies to stakeholders. Collaborate with CMC teams and Regulatory Affairs to develop residual impurity control strategies, specifications, and regulatory submissions. Manage vendor activities and oversee outsourced work including critical reagents, HCP coverage analysis, and CRO support. Lead implementation of new technologies and data‑driven approaches to improve throughput and sensitivity of impurity assays. Author and/or review SOPs, technical protocols and reports, and regulatory filings. Foster a high‑performance culture by coaching and mentoring scientists, promoting scientific excellence, accountability, and ownership. Present findings and strategies at internal cross‑functional meetings, technical forums, and external conferences. Participate in industry consortia on relevant topics and align internal strategies with industry practice. Qualifications Education & Experience Ph.D. in Biochemistry, Analytical Chemistry, Chemical Engineering, Pharmaceutical Sciences or related discipline with 6+ years of related industry experience, including 5+ years on residual impurity method development; or Master's degree with 12+ years of related industry experience; or Bachelor's degree with 14+ years of related industry experience 2+ years of people management experience with demonstrated ability to coach, develop and motivate high‑performing teams Prior experience in preparing analytical sections of IND, BLA and regulatory responses. Knowledge, Skills and Abilities Deep knowledge of residual impurity assay development (e.g. ELISA for residual protein, qPCR for DNA) Excellent troubleshooting and problem‑solving skills, with a systematic, data‑driven approach to resolving technical challenges Strong sense of accountability and ownership; consistently delivers to project goals and regulatory milestones Ability to manage multiple projects and priorities in a dynamic, cross‑functional environment Skilled in stakeholder management, with clear, proactive, and collaborative communication style Strong technical writing skills and attention to detail in documentation and data review Experience mentoring and developing scientific staff; promotes open communication and teamwork Solid understanding of CMC strategy, regulatory expectations, and phase appropriate analytical requirements Strong track record of independent troubleshooting, root cause investigation, and method remediation for impurity assays Proven success in delivering high‑quality results on time, even under changing priorities and compressed timelines. Demonstrated leadership and influence in cross‑functional matrix environments Preferred Qualifications Familiarity with potency assays, physiochemical assays and other characterization assays Knowledge in novel techniques on detecting and analyzing residual impurities Strong publication record and external scientific presence Experience in fostering partnership with clients through CDMO service Supervisory Responsibilities Yes. This role may supervise Associate Scientist and/or Scientist Additional Information The annual rate of pay for this position ranges from $129,500 - $197,500. For non‑exempt roles, and according to applicable regulations, there may be the possibility for overtime pay. This role is eligible for the Company's discretionary bonus and discretionary equity incentives. Eligible employees may participate in the Company's benefits programs, including medical / dental / vision / prescription coverage, employee wellness resources, 401(k) plan with employer match, access to an Employee Stock Purchase Plan, (ESPP), paid time off & paid parental leave benefits, and disability benefits. The annual pay rate range is described in good faith, and the Company believes is the range of possible compensation for this role at the time of this posting depending on the candidate's experience, qualifications, geographic location, and other factors permitted by law. The Company may ultimately pay more or less than the posted range, and this range may be modified in the future. No amount is considered to be wages or compensation until such amount is earned, vested, and determinable under the terms and conditions of the applicable policies and plans. The amount and availability of any bonus, commission, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole discretion unless and until paid and may be modified at the Company's sole discretion, consistent with the law. Statement MacroGenics is proud to be an equal opportunity employer. Employment selection and related decisions are made without regard to race, color, national origin, sex, gender identity, sexual orientation, religion, age, disability, protected veteran status, or any other characteristic protected by federal, state or local law. We are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the employment process, please email ******************** or call ************** and/or 711 for TTD/TTY service. Equal Opportunity Employer/Veterans/Disabled Equal Opportunity Employer. This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the Know Your Rights notice from the Department of Labor. We do not accept non‑solicited resumes or candidate submittals from search/recruiting agencies. #J-18808-Ljbffr
    $129.5k-197.5k yearly 3d ago
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  • Cell Culture Scientist

    Astrix 4.1company rating

    Associate scientist job in Bethesda, MD

    Manufactures cell and gene therapies for phase I and II clinical trials; (2) processes hematopoietic stem cell grafts for transplantation; (3) develops new cell therapies; (4) performs in-process and lot release testing of cell and gene therapies; (5) develops new assays to test cell and gene therapies; and (6) prepares chemistry, manufacturing, and controls (CMC) documents for investigational new drugs (IND) and summary data for annual reports to the Food and Drug Administration (FDA). ROLES / RESPONSIBILITES Build and optimize a robust cGMP compliant platform for generation, expansion and cryopreservation of autologous induced pluripotent stem cells (iPSCs) from peripheral blood derived CD34+ cells. Differentiate iPSCs to retinal pigment epithelial cells (RPE) to develop an iRPE patch for a phase I clinical trial to treat "dry" age related macular degeneration. Update and validate SOPs related to CD34 expansion, iPSC culturing, and RPE differentiation Manage a day to day operation of GMP facility Maintain iPSC colonies and freeze their early passages. GMP and aseptic culturing of iPCSs and differentiation of patient iPSCs into Retinal pigment epithelium (RPE) and maintenance of those RPE cultures. This work will include: Preparing media, supplements, and reagents needed cell culture work. Maintaining the cell culture room biosafety level 2 standards and maintaining aseptic conditions in cell culture flow hoods, incubators, and prepare sterile tools needed for work with cell cultures. The cell culture maintenance work will require working for short periods of times on the weekends and some holidays. Work to characterize the iPSC colonies for their pluripotency. This will require: Immunostaining of iPSCs, preparing RNA and cDNA from iPSCs, and Performing qRT-PCR assays. Additionally they will perform three germ layer assay based functional characterization of iPSCs. This work will also include any cell types that act as control for his iPSC work. Prepare regulatory documents for FDA and technology transfer Coordinate transfer of lab-technology to Good Manufacturing Practice (GMP suite) Develop Standard Operating Procedures (SOPs) with the Contract Research Organization (CRO) in relation to the cell therapy project. DESIRED BACKGROUND · Prior cell culture experience is required · Prior experience working in a cGMP environment is required
    $71k-105k yearly est. 4d ago
  • Principal Associate, Data Scientist - LLM Customization Team

    Capital One National Association 4.7company rating

    Associate scientist job in McLean, VA

    Data is at the center of everything we do. As a startup, we disrupted the credit card industry by individually personalizing every credit card offer using statistical modeling and relational database, cutting edge technology in 1988! Fast-forward a few years, and this little innovation and our passion for data has skyrocketed us to a Fortune 200 company and a leader in the world of data‑driven decision‑making. As a Data Scientist at Capital One, you'll be part of a team that's leading the next wave of disruption at a whole new scale, using the latest in computing and machine learning technologies and operating across billions of customer records to unlock the big opportunities that help everyday people save money, time and agony in their financial lives. Team Description The LLM Customization team is on the cutting edge of GenAI and at the center of bringing our vision for AI at Capital One to life. The work of the AI Training Team touches every aspect of the model development life cycle and our deployed models in production drive business impact with visibility from our C‑Suite. Our team creates unprecedented amounts of high quality data for training and testing GenAI models; we care about how it's created, what's in those datasets, and the impact they have We are invested in building capabilities for evaluating and monitoring generative models; these methods must be state of the art, easy to use, and trusted by our users and contributors Horizontal capabilities enable vertical use case work; the team builds search, summarization, RAG, and agentic workflows for integration in production applications across the company We learn from our colleagues, attend conferences, publish papers, and maintain strong connections to the research community. In this role, you will: Partner with a cross‑functional team of data scientists, software engineers, machine learning engineers and product managers to deliver AI powered products that change how customers interact with their money. Leverage a broad stack of technologies - Pytorch, AWS Ultraclusters, Hugging Face, LangChain, Lightning, VectorDBs, and more - to reveal the insights hidden within huge volumes of numeric and textual data. Be the expert in Natural Language Processing (NLP) to harness the power of Large Language Models (LLMs), adapt and finetune them for customer facing applications and features. Build machine learning and NLP models through all phases of development, from design through training, evaluation, and validation; partnering with engineering teams to operationalize them in scalable and resilient production systems that serve 80+ million customers. Flex your interpersonal skills to translate the complexity of your work into tangible business goals. The Ideal Candidate is: Customer first. You love the process of analyzing and creating, but also share our passion to do the right thing. You know at the end of the day it's about making the right decision for our customers. Innovative. You continually research and evaluate emerging technologies. You stay current on published state‑of‑the‑art methods, technologies, and applications and seek out opportunities to apply them. Creative. You thrive on bringing definition to big, undefined problems. You love asking questions and pushing hard to find answers. You're not afraid to share a new idea. A leader. You challenge conventional thinking and work with stakeholders to identify and improve the status quo. You're passionate about talent development for your own team and beyond. Technical. You're comfortable with advanced ML and DL technologies including language models and are passionate about developing further. You have hands‑on experience working with LLMs and solutions using open‑source tools and cloud computing platforms. Influential. You are passionate about AI/ML and can bring along a cross functional team in breakthrough innovations. You communicate clearly and effectively to share your findings with non‑technical audiences. You are experienced in training language models or large computer vision models as well as have expertise in one or more key subdomains such as training optimization, self‑supervised learning, explainability, RLHF. You have an engineering mindset as shown by a track record of delivering models at scale both in training data and inference volumes. You have experience in delivering libraries, platforms, or solution level code to existing products. Basic Qualifications Currently has, or is in the process of obtaining one of the following with an expectation that the required degree will be obtained on or before the scheduled start date: A Bachelor's Degree in a quantitative field (Statistics, Economics, Operations Research, Analytics, Mathematics, Computer Science, or a related quantitative field) plus 5 years of experience performing data analytics A Master's Degree in a quantitative field or an MBA with a quantitative concentration plus 3 years of experience performing data analytics A PhD in a quantitative field (Statistics, Economics, Operations Research, Analytics, Mathematics, Computer Science, or a related quantitative field) Preferred Qualifications Master's Degree in “STEM” field (Science, Technology, Engineering, or Mathematics) plus 3 years of experience in data analytics, or PhD in “STEM” field (Science, Technology, Engineering, or Mathematics) At least 1 year of experience working with AWS At least 3 years' experience in Python, Scala, or R At least 3 years' experience with machine learning At least 3 years' experience with SQL Capital One will consider sponsoring a qualified applicant for employment authorization for this position. The minimum and maximum full‑time annual salaries for this role are listed below, by location. Please note that this salary information is solely for candidates hired to perform work within one of these locations, and refers to the amount Capital One is willing to pay at the time of this posting. Salaries for part‑time roles will be prorated based upon the agreed upon number of hours to be regularly worked. McLean, VA: $158,600 - $181,000 for Principal Associate, Data Science New York, NY: $173,000 - $197,400 for Principal Associate, Data Science San Jose, CA: $173,000 - $197,400 for Principal Associate, Data Science Candidates hired to work in other locations will be subject to the pay range associated with that location, and the actual annualized salary amount offered to any candidate at the time of hire will be reflected solely in the candidate's offer letter. This role is also eligible to earn performance based incentive compensation, which may include cash bonus(es) and/or long term incentives (LTI). Incentives could be discretionary or non discretionary depending on the plan. Capital One offers a comprehensive, competitive, and inclusive set of health, financial and other benefits that support your total well‑being. Learn more at the Capital One Careers website. Eligibility varies based on full or part‑time status, exempt or non‑exempt status, and management level. This role is expected to accept applications for a minimum of 5 business days. No agencies please. Capital One is an equal opportunity employer (EOE, including disability/vet) committed to non‑discrimination in compliance with applicable federal, state, and local laws. Capital One promotes a drug‑free workplace. Capital One will consider for employment qualified applicants with a criminal history in a manner consistent with the requirements of applicable laws regarding criminal background inquiries, including, to the extent applicable, Article 23‑A of the New York Correction Law; San Francisco, California Police Code Article 49, Sections 4901‑4920; New York City's Fair Chance Act; Philadelphia's Fair Criminal Records Screening Act; and other applicable federal, state, and local laws and regulations concerning criminal background inquiries. If you have visited our website in search of information on employment opportunities or to apply for a position, and you require an accommodation, please contact Capital One Recruiting at 1‑************ or via email at RecruitingAccommodation@capitalone.com. All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodations. For technical support or questions about Capital One's recruiting process, please send an email to **********************. Capital One does not provide, endorse nor guarantee and is not liable for third‑party products, services, educational tools or other information available through this site. Capital One Financial is made up of several different entities. Please note that any position posted in Canada is for Capital One Canada, any position posted in the United Kingdom is for Capital One Europe and any position posted in the Philippines is for Capital One Philippines Service Corp. (COPSSC). #J-18808-Ljbffr
    $173k-197.4k yearly 1d ago
  • Principal Research Scientist - AI & Machine Learning

    Novateur Research Solutions

    Associate scientist job in Ashburn, VA

    Novateur stands for Innovation. We value creativity, vision, collaboration, and above all, ambition to innovate. Novateur Research Solutions is an R&D firm located in Northern Virginia, developing intelligent systems that push the boundaries of computer vision, AI, and large-scale learning. We are hiring a Principal Research Scientist to lead cutting-edge programs in AI, computer vision, and intelligent systems. This role offers leadership opportunities to define new research directions and shape next-generation technologies. Responsibilities: • Serve as PI or co-PI on government-funded R&D programs. • Conceive, design, and oversee research in learning systems, spatiotemporal modeling, and geo-localization. • Publish, present, and contribute thought leadership to the AI community. • Mentor research staff and guide proposal development. Requirements: • PhD with 7+ years of research experience. • Demonstrated leadership in ML, vision, or scientific computing. • Record of funding, publications, and technical impact. • U.S. Citizen or Permanent Resident. Preferred: • Experience with multimodal learning, uncertainty quantification, or causal inference. Why Novateur? Join a team that values creativity and initiative. At Novateur, you'll lead transformative projects that redefine what's possible in intelligent systems. Company Benefits: Novateur offers competitive pay and benefits comparable to Fortune 500 companies that include a wide choice of healthcare options with generous company subsidy, 401(k) with generous employer match, paid holidays and paid time off increasing with tenure, and company paid short-term disability, long-term disability, and life insurance. We offer a work environment which fosters individual thinking along with collaboration opportunities within and beyond Novateur. In return, we expect a high level of performance and passion to deliver enduring results for our clients.
    $86k-125k yearly est. 1d ago
  • Associate Scientist II, Molecular & Computational Biology

    Tonix Pharmaceutical 3.8company rating

    Associate scientist job in Frederick, MD

    About Tonix* Tonix is a fully integrated biotechnology company, publicly traded on NASDAQ (ticker: TNXP), with marketed products and a pipeline of development candidates The Company is focused on commercializing, developing, discovering, and licensing therapeutics to treat and prevent human disease. In August 2025, Tonix received FDA approval for Tonmya (cyclobenzaprine HCl sublingual tablets), a first-in-class, once-daily, non-opioid treatment for fibromyalgia. Tonmya is the first new fibromyalgia therapy approved in over 15 years, following successful Phase 3 trials demonstrating significant symptom improvement. Commercial launch is expected in the fourth quarter of 2025. Tonix also markets Zembrace SymTouch (sumatriptan injection) 3 mg and Tosymra (sumatriptan nasal spray) 10 mg, both indicated for the treatment of acute migraine with or without aura in adults. Tonix's development portfolio includes product candidates in central nervous system (CNS), immunology, immuno-oncology infectious disease and rare disease. The CNS pipeline features both small molecules and biologics to treat pain, neurologic, psychiatric, and addiction conditions. The immunology portfolio includes biologics to address organ transplant rejection, autoimmunity, and cancer. The infectious disease pipeline includes a vaccine in development to prevent smallpox and monkeypox, which also serves as a live virus vaccine platform for other infectious diseases. Finally, the rare disease portfolio includes a product in development for Prader-Willi syndrome, which has both orphan drug designation and rare pediatric disease designation grants from the FDA. Tonix owns and operates a state-of-the art infectious disease research facility in Frederick, Md. Please visit ******************* for specifics on the pipeline. * All of Tonix's product candidates are investigational new drugs or biologics and have not been approved for any indication. Position Overview Tonix Pharmaceuticals is seeking a highly motivated Associate Scientist to join our multidisciplinary R&D team at the Frederick Research & Development Center. This role integrates computational protein structure analysis with hands-on molecular biology and protein biochemistry. The successful candidate will contribute to host-directed therapeutic discovery, antiviral platforms, and vaccine design by combining AI/ML-based protein modeling with molecular biology and protein science to generate, express, and analyze protein targets. Key Responsibilities * Perform protein structure modeling and design using platforms such as AlphaFold2/3, ESM, RFdiffusion, ProteinMPNN, and NetMHC. * Build and refine bioinformatics workflows for large-scale sequence and structural analysis of host and viral proteins * Perform molecular cloning, PCR, DNA and RNA isolation, bacterial transformation, and mutagenesis to generate expression constructs. * Carry out protein expression and purification followed by protein characterization * Collaborate with Tonix's imaging and cell biology teams to translate computational predictions into testable hypotheses in assays and animal models. * Contribute to the development of user-friendly computational pipelines and visualization tools for internal scientists. * Document and communicate results in reports, regulatory filings, and presentations to internal teams, collaborators, and external partners. * Maintain awareness of emerging computational biology technologies to enhance Tonix's drug discovery capabilities. Required Qualifications * B.S. or M.S. in Microbiology, Biochemistry, Bioinformatics, Computational Biology, or related field. * Hands-on experience with protein structure prediction and computational protein design tools. * Familiarity with core molecular biology and protein biochemistry methods (PCR, cloning, bacterial expression, Western blotting). * Strong communication skills and ability to work in cross-functional teams within Tonix's integrated discovery pipeline. Preferred: * Experience with cloud computing platforms (Google Cloud, AWS) for large-scale protein modeling. * Exposure to machine learning approaches in protein design and immunology. * Prior experience with protein engineering for therapeutic applications. * Track record of contributions to publications, posters, or conference presentations. * Proficiency in Python, especially ML/AI packages. Experience in Linux operating systems and shell programming is desirable. Recruitment & Staffing Agencies Tonix does not accept agency resumes unless contacted directly by internal Tonix Talent Acquisition. Please do not forward resumes to Tonix employees or any other company location; Tonix is not responsible for any fees related to unsolicited resumes. Compensation & Benefits Annualized base salary ranges from $60,000 to $90,000 plus target incentive; actual salaries will vary and may be above or below this range commensurate with several factors including experience, education, training, location, and merit. Tonix provides a comprehensive compensation and benefits package which includes: * Medical, Dental & Vision Insurance, Basic and Voluntary Life and AD&D Insurance, Short- and Long-Term Disability Insurance, Flexible Spending Accounts, Health Savings Account, and Employee Assistance Programs * Pet Insurance * Retirement Savings 401k with company match and annual discretionary stock options * Generous Paid Time Off, Sick Time, & Paid Holidays * Career Development and Training Tonix provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, sex, national origin, age, genetics, or any other characteristic protected by law. In addition to federal law requirements, Tonix complies with applicable state and local laws governing nondiscrimination in employment. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfers, leaves of absence, compensation, and training. Tonix expressly prohibits any form of workplace harassment based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, genetic, information, disability, veteran status, or any other characteristic protected by law.
    $60k-90k yearly 56d ago
  • Support Scientist IV

    STC 4.0company rating

    Associate scientist job in Greenbelt, MD

    About Science and Technology Corporation (STC): Founded in 1979, Science and Technology Corporation (STC) provides award-winning scientific, engineering, and technical services to U.S. Government and industry partners. We are dedicated to advancing our customers' missions through innovation, trusted partnerships, and science-driven engineering excellence. With integrity and precision, we deliver reliable solutions that make a real impact. At STC, we invest in our employees' growth, well-being, and success-fostering a culture of respect, trust, and empowerment. Join our world-class team and help shape the future of science and technology. Employment Category: Full-Time Location: Greenbelt, MD - On-site with global collaborations Travel: Frequent (domestic & international field missions, scientific meetings) Security Clearance: None Citizenship: Requires U.S. Citizenship Salary: $130K - $175K Job Description: The Support Scientist IV will serve as a senior researcher under the ATMOS contract at NASA GSFC, leading major research efforts in atmospheric science. This includes computational modeling, instrument development, and analysis of large satellite datasets. The role requires collaboration with scientists across institutions and management of junior researchers. ATMOS is a NASA support services contract that provides advanced scientific, engineering, and technical expertise to enable Earth and space science missions. The program supports research, data analysis, technology development, and mission operations across multiple NASA centers. Through ATMOS, our teams deliver innovative solutions that help advance NASA's mission and expand scientific discovery. Key Responsibilities Include: Plan and direct scientific research tasks in atmospheric science. Lead development of computational models and instrumentation concepts. Publish extensively and represent NASA at international conferences. Mentor and oversee other scientists within project teams. Benefits: Paid Time Off Starting at 80 hrs/yr, 11 Federal holidays, and 40 hrs/yr Sick Leave 401K with up to 4% employer matching contribution Comprehensive Medical, Dental, Vision Insurance, Short Term/Long Term Disability Flexible spending account Health savings account Tuition reimbursement Requirements 10+ years of scientific research experience. 5+ years of leadership in scientific project management. Strong background in atmospheric science with proven publication record. Advanced programming expertise (FORTRAN, C/C++, Python). Education: Ph.D. in atmospheric science, physical science, mathematics, or computer science, or M.S. degree in one of the listed disciplines, plus ten years of experience relevant to the position. This experience is in addition to the experience required for the position level.
    $130k-175k yearly 60d+ ago
  • Downstream Scientist

    ZP Group 4.0company rating

    Associate scientist job in Frederick, MD

    Piper Companies is looking for a Downstream Scientist to join a leading biopharmaceutical company located in Frederick, MD. Responsibilities of the Downstream Scientist include: * Execute and optimize purification processes including chromatography, viral inactivation, filtration, and UF/DF * Support technology transfer of downstream processes to commercial manufacturing * Conduct small-scale purification studies for process characterization and optimization * Analyze experimental data using MVDA tools Qualifications for the Downstream Scientist include: * 3-7 years of experience in downstream process development or technology transfer in biologics manufacturing within a cGMP pharma or CDMO environment * Proficiency in chromatography, viral inactivation, filtration, and UF/DF operations * Bachelor's degree in a relevant scientific discipline Compensation for Downstream Scientist includes: * Rate Range: $85,000-$120,000+ * Comprehensive Benefit Package: Cigna Medical/Dental/Vision, 401K, Sick Leave as Required by Law This job is open for applications on October 13, 2025. Applications will be accepted at least 30 days from the posting date. Keywords: Downstream Scientist, Biologics, Purification, Chromatography, UF/DF, Technology Transfer, MVDA, GMP, CMC, Biopharma, Viral Inactivation, Filtration, Process Development, Scale-Up, Process Characterization, Good Documentation Practices, Manufacturing Sciences & Technology, CDMO, cGMP, Large Molecule Therapeutics, Data Analysis, Process Optimization #LI-MU1 #LI-ONSITE
    $85k-120k yearly 60d+ ago
  • Associate Scientist Antibody Engineering

    Actalent

    Associate scientist job in Rockville, MD

    Join our dynamic antibody engineering group as an Associate Scientist, contributing to the design, construction, and evaluation of monoclonal and bispecific antibodies. Utilize modern molecular techniques to engineer antibodies and conduct immunoassays to assess their function, stability, and serum clearance. Responsibilities + Contribute to the engineering and evaluation of monoclonal and bispecific antibodies. + Utilize molecular techniques and computational tools to enhance antibody affinity, stability, and developability. + Conduct immunoassays such as ELISA to evaluate antibody function, stability, and serum clearance. + Employ analytical instruments like flow cytometry to assess antibody functions. + Design and engineer various antibody formats using molecular techniques. Essential Skills + Experience with monoclonal antibodies, ELISA, and immunoassay techniques. + Proficiency in molecular cloning, RNA isolation, and sequencing analysis. + Hands-on experience in immune-binding assays such as ELISA. + Strong experience in molecular biology techniques including mutagenesis and Quikchange. + Competence in using software for plasmid map generation and nucleotide sequence analysis, such as Snapgene. Additional Skills & Qualifications + Bachelor's Degree in a scientific discipline with a minimum of two years of related experience or a Master's Degree in a scientific discipline. + Industry experience preferred, with 4-5 years being ideal for Scientist level. + Basic experience with programming languages such as Python, VBA, or R is advantageous. + Exceptional attention to detail and rigorous experimental practices. + Excellent time-management skills. Work Environment The role is based in a lab environment, requiring full onsite presence. Expect to spend 15-20% of your time at your desk. As part of a mid-sized company, you will have the opportunity to engage with many exciting products in the pipeline. Job Type & Location This is a Contract position based out of Rockville, MD. Pay and Benefits The pay range for this position is $30.00 - $40.00/hr. Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following: - Medical, dental & vision - Critical Illness, Accident, and Hospital - 401(k) Retirement Plan - Pre-tax and Roth post-tax contributions available - Life Insurance (Voluntary Life & AD&D for the employee and dependents) - Short and long-term disability - Health Spending Account (HSA) - Transportation benefits - Employee Assistance Program - Time Off/Leave (PTO, Vacation or Sick Leave) Workplace Type This is a fully onsite position in Rockville,MD. Application Deadline This position is anticipated to close on Jan 21, 2026. About Actalent Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 30,000 consultants and more than 4,500 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500. The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law. If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing due to a disability, please email actalentaccommodation@actalentservices.com (%20actalentaccommodation@actalentservices.com) for other accommodation options.
    $30-40 hourly 12d ago
  • Scientist, Discovery

    Arcellx Inc. 4.0company rating

    Associate scientist job in Rockville, MD

    Who We Are Arcellx is a public, clinical-stage biotechnology company reimagining cell therapy by engineering innovative immunotherapies for patients with cancer and other incurable diseases. We believe that cell therapies are one of the forward pillars of medicine and our mission is to destroy cancer and advance humanity by developing cell therapies that are safer, more effective, and more broadly accessible. Our team members are made up of talented innovators and dreamers working from our offices in Rockville, Maryland, and Redwood City, California. At Arcellx, we hire exceptional people and create a fun, diverse, supportive, and informal environment that allows everyone to do their best work. What Matters to Us Living our core values is essential to maintaining a work environment that is high-performing, inclusive, and collaborative. We look for candidates who demonstrate strong values alignment and bring different backgrounds, viewpoints, and abilities to the team. Arcellx Core Values * Start with authenticity: We foster an inclusive environment where each person can bring their authentic self to work. * Think 'we' before 'me': We prioritize collective success, collaborating and supporting one another to achieve our shared goals. * Embrace the challenge: We deliver exceptional results by working with shared determination and a commitment to doing what's right. How You'll Make a Difference As a Scientist, your mission is to execute protein and molecular biology engineering strategies to advance projects within Arcellx's Discovery group. Engaging with a cross-functional team in a fast-paced environment, you'll identify and develop Arcellx's lead therapeutic candidates. Our potentially life-saving treatments would not exist without the work of our talented Discovery scientists; this role will have a tremendous impact on our pipeline and ability to deliver novel and effective drugs to patients. The "Fine Print" - What You'll Do * Work with an interdisciplinary team of scientists to design, engineer and express recombinant proteins for use in the discovery and development of cancer therapies. * Design, construct and evaluate expression plasmids. Perform transfections, transductions, phage and yeast display enabled selections & screenings, binding kinetic assessments and flow cytometry as needed. * Develop new methods, technologies and processes when necessary for project. * Exercise significant technical discretion in the design, execution and interpretation of experiments. * Communicate progress and project recommendations to team members. Skills and Experience We Look For * BS or MS in the life sciences (e.g., biology, genetics, biochemistry, chemistry, chemical engineering, bioengineering) with 4-8 years post-degree lab experience or PhD in the life sciences with 0-3 years post-degree experience. * Must demonstrate mastery of molecular biology methods, including primer design, PCR, gel electrophoresis, expression construct design cloning and sequence analysis. * Preferred skills include: methods for the characterization of recombinant protein quality and binding, protein display (phage, yeast and library preparation). * Preference for experience in drug development, immunology or protein engineering. * The ability to independently plan, organize, and prioritize work activities. The ability to work collaboratively in interdisciplinary teams. Rewards at Arcellx Our people are our greatest asset, and supporting their well-being is an essential part of delivering on our mission and impacting the lives of patients. Putting this belief into practice means offering strong compensation and benefits. The base salary range for this position is $100,000 - $120,000 per year. Where a candidate falls within that range is determined by factors such as years of experience. Our compensation package also includes an annual bonus based on company goals and an equity (RSU) grant. We do offer relocation assistance for roles if required. Our market-leading benefits package includes: 100% coverage for medical, dental and vision for team members and dependents, unlimited vacation, a 3-day weekend every month, fully-paid parental leave for up to 6 months, tuition reimbursement, 401k employer contribution and more. Join us in our quest to reimagine cell therapy and destroy cancer. For more on our technology, culture, and team, go to **************** #LI-Onsite
    $100k-120k yearly 47d ago
  • Scientist

    Vandstrom

    Associate scientist job in Gaithersburg, MD

    Vandstrom is seeking a scientist with expertise in integral membrane proteins. Please refer to the attached job description for the details.
    $69k-101k yearly est. Auto-Apply 60d+ ago
  • Applied AI Health Scientist (ARPA-H)

    Ripple Effect 3.9company rating

    Associate scientist job in Washington, DC

    Job Description General Information Job Code: SHR-BI-05T Employee Type: Exempt, Full-Time Regular Telework: Ad hoc as determined by client Salary Range: $129,985.76 - $149,483.62 per year (how we pay and promote) Citizenship: U.S. Citizen as required by client Position Overview Are you passionate about managing information to drive innovation and impact? As a Applied AI Health Scientist supporting our client, you will play a pivotal role in shaping our success. This is a Science and Engineering and Technical Advisor (SETA) role in the Proactive Health Mission Office at the Advanced Research Projects Agency for Health (ARPA-H) responsible for providing expertise in artificial intelligence and machine learning to support a program advancing AI diagnostics for rare diseases. Successful candidates have the ability to critically assess technical approaches, advise program leadership, and ensure that funded performers and partners are meeting the highest standards of rigor, reproducibility, and real-world applicability. You will contribute expertise across the full lifecycle of AI system development: data aggregation and curation, model training and benchmarking, and deployment/validation in real-world clinical settings. Primary Responsibilities While not an exhaustive list, the key duties for the position include: Review and evaluate AI/ML technical proposals and deliverables from external teams. Provide guidance on model development, training methods, and validation strategies. Advise on integration of multimodal health data (EHR, imaging, genomic, and patient-reported). Assess alignment of model architectures and approaches with program goals and clinical use cases. Evaluate benchmarking results and provide feedback on methodological soundness. Advise on deployment considerations, including interpretability, reliability, and safety in real-world settings. Collaborate with clinical SMEs to ensure AI outputs align with clinician expectations and workflows. Identify risks, gaps, or weaknesses in technical approaches and recommend corrective actions. Support program leadership with technical assessments, reports, and recommendations. Produce high-quality written reports and presentations that synthesize complex technical findings for diverse audiences. Requirements Minimum Education and Experience: Master's degree in Computer Science, Machine Learning, Data Science, or related field. 10+ years of relevant professional experience. Basic Requirements: Experience applying advanced ML methods (LLMs, deep learning, etc) to complex health datasets. Familiarity with clinical and biomedical data types, including EHR, genomic, and imaging data. Demonstrated ability to review, critique, and guide AI/ML technical work at a high level. Strong understanding of evaluation methods for AI/ML, including robustness, fairness, interpretability, and reproducibility. Strong written and visual communication skills, with ability to produce high-quality reports and presentations. Intermediate experience with Microsoft Office productivity software and collaboration tools such as Microsoft Teams and SharePoint. Skills That Set You Apart: Experience in healthcare AI or biomedical applications. Familiarity with the rare disease field Prior involvement in technical advisory, evaluation, or SETA-style roles. Experience working with interdisciplinary teams including clinicians and patient stakeholders. Experience working in an early-stage, fast-paced, startup environment About Ripple Effect Ripple Effect is an award-winning women-owned, 200-person company of communicators, scientists, researchers, and analysts. Established in 2003, and named as one of the “Best and Brightest Companies to Work For” since 2020, Ripple Effect has earned acclaim for delivering unparalleled consulting services and top-tier talent across federal, private, and non-profit sectors. Benefits At Ripple Effect, we reward our employees for their contributions to our mission. Our comprehensive total rewards package includes competitive pay, exceptional benefits, and a range of programs that support your work/life balance and personalized preferences. Learn more about our benefits and culture here.
    $130k-149.5k yearly 11d ago
  • Flow Cytometry Scientist

    Cs&S Staffing Solutions

    Associate scientist job in Rockville, MD

    Please, review and apply for this position through the QCI system following the link below (Copy and Paste): http://jobs.qcitech.com/jobseeker/Flow_Cytometry_Scientist_J02098387.aspx *You can apply through Indeed using mobile devices with this link. Additional Information
    $69k-101k yearly est. 15h ago
  • Flow Cytometry Scientist

    CS&S Staffing Solutions

    Associate scientist job in Rockville, MD

    Please, review and apply for this position through the QCI system following the link below (Copy and Paste): http://jobs.qcitech.com/jobseeker/Flow_Cytometry_Scientist_J02098387.aspx *You can apply through Indeed using mobile devices with this link. Additional Information
    $69k-101k yearly est. 60d+ ago
  • NLP Scientist

    NIH-NCBI

    Associate scientist job in Bethesda, MD

    Black Canyon Consulting (BCC) is actively looking for an experienced Natural Language Processing (NLP) Scientist to support the National Library of Medicine (NLM) at the National Institutes of Health (NIH). This individual will create a genotype-phenotype database focused on influenza viruses by developing an NLP pipeline that includes named entity recognition, entity linking, and relationship extraction. The resulting database will be used by the influenza research community for risk assessment. If you enjoy being a part of a high performing, professional service and technology focused organization, please apply today! Duties & Responsibilities: Design and implement an NLP pipeline that includes named entity recognition, entity linking, and relationship extraction. Extract genotype-phenotype relations for influenza from literature and populate the database. Construct and maintain the genotype-phenotype database. Document the approach, the pipeline, and the database structure. Core Expertise: Formal education with major study in an academic field related to the medical field, health sciences or allied sciences appropriate to the work of the position. Experience with NLP methods, including named entity recognition, entity linking, and relationship extraction. Ability to develop an NLP pipeline and produce structured outputs from literature sources, Preferred Qualifications: Domain knowledge about influenza or related areas. Contract Period This position is currently set to be 9-12 months in length.
    $69k-101k yearly est. Auto-Apply 60d+ ago
  • General Scientist

    Prosidian Consulting

    Associate scientist job in Washington, DC

    ProSidian is a Management and Operations Consulting Services Firm focusing on providing value to clients through tailored solutions based on industry leading practices. ProSidian services focus on the broad spectrum of Risk Management, Compliance, Business Process, IT Effectiveness, Energy & Sustainability, and Talent Management. We help forward thinking clients solve problems and improve operations. Launched by former Big 4 Management Consultants; our multidisciplinary teams bring together the talents of nearly 190 professionals nationally to complete a wide variety of engagements for Private Companies, Fortune 1,000 Enterprises, and Government Agencies of all sizes. Our Services are deployed across the enterprise, target drivers of economic profit (growth, margin and efficiency), and are aligned at the intersections of assets, processes, policies and people delivering value. ProSidian clients represent a broad spectrum of industries to include but are not limited to Energy, Manufacturing, Chemical, Retail, Healthcare, Telecommunications, Hospitality, Pharmaceuticals, Banking & Financial Services, Transportation, Federal and State Government Agencies. Learn More About ProSidian Consulting at ****************** Job Description Performs professional environmental services, including consulting, program planning, information management, assessment, characterization, monitoring, social assessment, field logistics, sampling, studies, analysis, compliance, advisory, impact statements and assessments under NEPA, assessments and investigations under RCRA and CERCLA, and remediation and reclamation. Provides expertise in field of study including but not limited to environmental science, geography, archaeology, chemistry, botany, biology, etc. Qualifications Master's or Ph.D. degree in agriculture, agronomy, plant science, animal science, soil science, agricultural economics, environmental science, or a related field. Experience conducting scientific research, preferably in agriculture or related disciplines. Strong analytical and quantitative skills, including proficiency in statistical analysis and data interpretation. Excellent written and oral communication skills, with the ability to communicate scientific concepts effectively to diverse audiences. Ability to work independently and collaboratively in a multidisciplinary research environment. Experience in grant writing, project management, and budget oversight for research projects is preferred. Knowledge of USDA programs, priorities, and initiatives related to agricultural research and development is desirable. Commitment to diversity, equity, and inclusion in research practices and team dynamics. Additional Information CORE COMPETENCIES Teamwork - ability to foster teamwork collaboratively as a participant, and effectively as a team leader Leadership - ability to guide and lead colleagues on projects and initiatives Business Acumen - understanding and insight into how organizations perform, including business processes, data, systems, and people Communication - ability to effectively communicate to stakeholders of all levels Motivation - persistent in pursuit of quality and optimal client and company solutions Agility - ability to quickly understand and transition between different projects, concepts, initiatives, or work streams Judgment - exercises prudence and insight in decision-making process while mindful of other stakeholders and long-term ramifications Organization - ability to manage projects and activity, and prioritize tasks BENEFITS AND HIGHLIGHTS At ProSidian, we invest in our employees to help them stay healthy and achieve work-life balance. Our growing list of benefits currently include the following for Full Time Employees: • Competitive Compensation: Pay range begins in the competitive ranges with Group Health Benefits, Pre-tax Employee Benefits, and Performance Incentives. Group Health Insurance Benefits: • Medical: ProSidian partners with BC/BS, to offer a range of medical plans, including high-deductible health plans or PPOs. • Dental: ProSidian dental carriers - Delta, Aetna, Guardian, and MetLife. • Vision: ProSidian offers high/low vision plans through 2 carriers: Aetna and VSP. For medical and dental benefits, the Company contributes a fixed dollar amount each month towards the plan you elect. Contributions are deducted on a Pre-tax basis. • 401(k) Retirement Savings Plan: 401(k) Retirement Savings Plans help you save for your retirement for eligible employees. A range of investment options are available with a personal financial planner to assist you. The Plan is a pre-tax Safe Harbor 401(k) Retirement Savings Plan with a company match. • Vacation and Paid Time-Off (PTO) Benefits: Eligible employees use PTO for vacation, a doctor's appointment, or any number of events in your life. Currently these benefits include Vacation/Sick days - 2 weeks/3 days | Holidays - 10 ProSidian and Government Days are given. • Pre-Tax Payment Programs: Pre-Tax Payment Programs currently exist in the form of a Premium Only Plan (POP). These Plans offer a full Flexible Spending Account (FSA) Plan and a tax benefit for eligible employees. • Purchasing Discounts & Savings Plans: We want you to achieve financial success. We offer a Purchasing Discounts & Savings Plan through The Corporate Perks Benefit Program. This provides special discounts for eligible employees on products and services you buy on a daily basis. • Security Clearance: Due to the nature of our consulting engagements there are Security Clearance requirements for Engagement Teams handling sensitive Engagements in the Federal Marketplace. A Security Clearance is a valued asset in your professional portfolio and adds to your credentials. • Leverage-able Experience and Thought Leadership: By collaborating with firm leadership, other members of the team, as well as Fellows and collaborating partners in what is a flat organization, you'll make valuable professional connections, gain experience, and contribute to Thought Leadership while you build a basket of marketable experiences. • ProSidian Employee & Contractor Referral Bonus Program: ProSidian Consulting will pay up to 5k for all referrals employed for 90 days for candidates submitted through our Referral Program. • Performance Incentives: Due to the nature of our consulting engagements there are performance incentives associated with each new client that each employee works to pursue and support. • Flexible Spending Account: FSAs help you pay for eligible out-of-pocket health care and dependent day care expenses on a pre-tax basis. You determine your projected expenses for the Plan Year and then elect to set aside a portion of each paycheck into your FSA. • Supplemental Life/Accidental Death and Dismemberment Insurance : If you want extra protection for yourself and your eligible dependents, you have the option to elect supplemental life insurance. D&D covers death or dismemberment from an accident only. • Short- and Long-Term Disability Insurance: Disability insurance plans are designed to provide income protection while you recover from a disability. ADDITIONAL INFORMATION - The Best Way To Apply • ProSidian Consulting is an equal opportunity employer and considers qualified applicants for employment without regard to race, color, creed, religion, national origin, sex, sexual orientation, gender identity and expression, age, disability, or Vietnam era, or other eligible veteran status, or any other protected factor. All your information will be kept confidential according to EEO guidelines. • ProSidian Consulting has made a pledge to the Hiring Our Heroes Program of the U.S. Chamber of Commerce Foundation and the “I Hire Military” Initiative of The North Carolina Military Business Center (NCMBC) for the State of North Carolina. All applicants are encouraged to apply regardless of Veteran Status. • Furthermore, we believe in "HONOR ABOVE ALL" - be successful while doing things the right way. The pride comes out of the challenge; the reward is excellence in the work. FOR EASY APPLICATION USE OUR CAREER SITE LOCATED ON ************************* OR SEND YOUR RESUME'S, BIOS, AND SALARY EXPECTATION / RATES TO **********************. ONLY CANDIDATES WITH REQUIRED CRITERIA ARE CONSIDERED. Be sure to place the job reference code in the subject line of your email. Be sure to include your name, address, telephone number, total compensation package, employment history, and educational credentials. Risk Management | Compliance | Business Processes | IT Effectiveness | Engineering | Environmental | Sustainability | Human Capital
    $69k-102k yearly est. Easy Apply 60d+ ago
  • Scientist

    Saratoga Medical Center 4.3company rating

    Associate scientist job in Bethesda, MD

    Contractor(s) shall provide services in support of the overall functions of the Laboratory of Viral Diseases LVD/NIH located in Bethesda, Maryland. MANDATORY EDUCATION: PhD or Master's degree with at least five (5) years of post-masters experience. Minimum of three (3) years of experience working in a laboratory setting. Experience in Chromatin Immunoprecipitation Assays (ChIP Assays). FIELD OF STUDY: Immunology, Microbiology, Micropathology, Science, and Biology EXPERIENCE: Knowledge of statistics, of virology, and of epigenetics is required. Experience working with DNA viruses; titering, infection of tissue culture cells, fluorescent and confocal microscopy. Familiarity with bioinformatic analyses of RNA-Seq, ChIP-Seq, ATAC-seq, and protein purification chromatography.
    $76k-104k yearly est. Auto-Apply 60d+ ago
  • Fiber Laser Scientist

    NSS 4.4company rating

    Associate scientist job in Herndon, VA

    Fiber Laser Scientist Herndon, VA While working as a Fiber Laser Scientist at Fibertek, you will lead the design and development, integration, and test of advanced fiber laser systems typically with performance requirements beyond the state-of-the-art. Fibertek is a leader in the design, development, and delivery of advanced laser systems and technologies for military and aerospace applications. Your Job We are looking for and experienced and motivated fiber laser scientist or engineer to join a multi-disciplinary team and lead the design and demonstration of advanced laser systems. Example focus missions include space-based laser communications, lidar for tactical defense applications, earth-sensing lidar, and navigational lidars for planetary and docking missions. Fibertek's engineering teams simultaneously tackle laser optical performance beyond state-of-the-art while engineering systems for performance on challenging platforms with limited size, mass, and power and over stressing vibration, thermal, and/or radiation conditions. Delivered systems make a national impact to customers at NASA and throughout the defense community. The work-load will at times include multiple concurrent projects with a mix of short duration research programs and longer duration technology maturation programs resulting in a work culture that is team-oriented, intellectually stimulating, and consistently rewarding. Lead the engineering development of unique laser designs through modeling fiber laser performance, design analysis, component specification, and hardware assembly, integration, and test Coordinate and support the build, alignment, and performance characterization of fiber lasers including multi-stage amplifiers, phase & amplitude modulation implementation, spectral and coherent beam combining Coordinate and perform formal acceptance and qualification testing Participate in customer interactions including formal technical reviews Required Skills and Experience To exceed in this Fiber Laser Scientist role, you'll need the below expertise and experience: MS or PhD in Physics or Optical Engineering w/ a minimum of 5 years of direct hands-on fiber laser experience including designing, building, characterizing laser systems Knowledge of the laser theory and industry best practices associated with fiber laser systems including continuous wave lasers, pulsed, high peak power fiber, advanced fiber architectures, single-frequency injection locked lasers, low frequency noise lasers, electrical and thermal sub-systems. Expertise in laser physics of fiber lasers and amplifiers, including ytterbium, erbium, and/or thulium gain materials. Familiarity with relevant nonlinear processes and impacts to laser performance. Examples include Stimulated Brillouin Scattering, Four-Wave Mixing, Stimulated Raman Scattering, and Transverse Modulational Instability. Foundational understanding of fiber-optic components including types of fibers, pump lasers, couplers, modulators, isolators, mode-field adapters, polarization components, and others. Knowledge of tools for modeling fiber laser performance such as Matlab, RP Power Fiber or equivalent software Ability to design and execute experiments validating laser system performance and correlate the results with the expected performance Strong communication and documentation skills for efficient multidisciplinary communication US citizenship required Please apply today for this full-time Herndon-based Fiber Laser Scientist role and join the leader in the development of state-of-the-art laser and electro-optic solutions. Why Fibertek, Inc? At FIBERTEK, Inc. we pride ourselves in our innovation and customer success focused culture enabled by a creative and relaxed work environment with minimal bureaucracy. Fibertek fosters a progressive learning environment that values inspiration, promotes professional challenge and encourages personal growth. We offer a competitive and incentivized compensation package with excellent benefits. Fibertek, Inc. is an equal opportunity and affirmative action employer. Applicants are considered regardless of race, sex, gender identity, sexual orientation, religion, national origin, disability, protected Veteran status, age or any other protected characteristic in accordance with applicable law. If you need assistance or an accommodation for any part of the application process, please contact us by phone at ************ or via email at ***************.
    $75k-103k yearly est. Easy Apply 60d+ ago
  • Applied Scientist

    Improbable

    Associate scientist job in Arlington, VA

    Join Improbable U.S. Defense & National Security and you will help users leverage our synthetic environment development platform to plan and train for the most complex security threats in the world. Working along experts in AI, Machine Learning, computational modeling, and distributed systems, you will put multiplayer gaming technology to life-saving use. Our mission? To enable the most realistic and effective virtual worlds ever experienced. Our team in Arlington, VA, and across several other locations in the US, is focused on applying our technology to solve real-world Defense and National Security problems. At Improbable, you will be surrounded by people who want to improve everything and everyone around them, and who compel you to improve yourself. We're motivated by the fulfillment of solving hard problems to achieve something profound and transformative. Our applied scientists are solution focused, collaborating in diverse technical teams to design, build, deploy, and evaluate complex models and simulations that help solve a variety of real-world problems. Your work could entail anything from the creation of realistic synthetic entities and environments to modeling real world systems.Areas for Impact Bring together best in class models to build and iterate on the most appropriate application of Modeling & Simulation. Iteratively design and prototype models of real-world systems that enable our customers to interrogate the past, understand the present, and predict the future. Collaborate with engineers to implement high performance models in production environments. Work closely with Improbable's product team to enhance our foundational technology platform. Critically assess the type and quality of customer or open-source data and define modeling assumptions and capture uncertainty. Take ownership of ensuring and demonstrating the reliability of the models that we create. Work closely with our technology customers to understand their problems and develop use cases for Improbable technology. Additionally, you will drive thought leadership within the company and help our clients understand their needs and design their model and simulation strategies. This involves keeping up to date with a diverse body of cutting-edge research, designing and prototyping new technical approaches, and rapidly developing expertise in new subject areas to support new bids and projects. We'd like to hear from you if you identify with any of the following Strong background and experience in delivery of technical, data-rich projects ideally for external clients. Degree in a scientific, engineering, or mathematical field, ideally with a computational element. Demonstrated knowledge in a statistical modeling and analysis. Demonstrated experience with agent-based modeling, micro-simulation, computational social science, or modeling socio-technical systems. Experience using game engines such as Unity and Unreal. Pragmatic coding ability - with fluency in at least one relevant programming language and the openness to learn and adapt to a variety of languages. We use Python, R, Java, C, C++, and many related tools and libraries. Breaking down problem requirements, selecting effective analytical methods, and developing defensible solutions. Probabilistic programming. You can see our early open-sourced work here. Working with real, complex data, including geospatial data. Effectively communicating with clients in person, in writing, and with visualization. While we think the above experience could be important, we're keen to hear from people that believe they have valuable experience to bring to the role. If you identify with the team and mission, but not all of our requirements, then please still apply!We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.
    $60k-88k yearly est. Auto-Apply 60d+ ago
  • Machine Learning Scientist

    Systems Integration 4.3company rating

    Associate scientist job in Washington, DC

    Data Scientist Systems Integration, Inc. (SII) is a leading provider of customer experience, data analytics and digital transformation solutions . We are seeking a highly skilled Machine Learning Scientist to help the FBI uncover actionable insights from vast and complex data sets. This role focuses on identifying enterprise-level toolsets, applying advanced data mining techniques, and building predictive models that integrate with FBI systems. The ideal candidate will be a strategic thinker with deep technical expertise and the ability to communicate findings clearly across all levels of the organization. Responsibilities: Select, build, and optimize machine learning classifiers using advanced techniques Apply state-of-the-art data mining methods to extract meaningful patterns Enhance data collection procedures to ensure relevance for analytic systems Cleanse, process, and validate data integrity for analysis Conduct ad-hoc analyses and present results in a clear, actionable format Develop and monitor automated anomaly detection systems Design innovative approaches for handling and analyzing large-scale data sets Address fundamental challenges in data handling, search, and retention Solve complex data storage and retrieval issues Develop software solutions to improve data search and access processes Analyze results and deliver recommendations that support mission objectives. Qualifications: Must be US Citizen Requires a Top-Secret clearance (SCI Poly may be required later). Strong understanding of machine learning algorithms (e.g., kNN, Naive Bayes, SVM, Decision Forests) Proficiency with data science toolkits such as R, Weka, NumPy, and MATLAB Excellent communication and presentation skills Experience with tools like Microsoft Power BI, Anaconda, and SPSS Skilled in data visualization using D3.js, GGplot, or similar platforms Proficient in SQL and Hive for querying large datasets Experience with NoSQL databases (e.g., MongoDB, Cassandra, HBase) Solid foundation in applied statistics (distributions, testing, regression) Strong scripting and programming capabilities. Minimum 5 years of experience supporting data-driven projects of similar scope. Bachelor's degree required in data science, statistics, computer science or related field.
    $66k-97k yearly est. 60d+ ago
  • Scientist

    Camris 4.6company rating

    Associate scientist job in Bethesda, MD

    We are seeking a Scientist to support the National Institutes of Health's (NIH), world renowned National Institute of Allergy and Infectious Diseases (NIAID) in Bethesda, MD. Our NIAID professional, technical, and scientific support personnel are part of a preeminent team focused on positively impacting millions of lives around the world with groundbreaking research. Candidates will work at a prominent and vibrant NIAID worksite to directly support exciting ongoing research activities as a contractor team member. Accelerate your career and apply below to help us make a difference. CAMRIS International is a dynamic clinical research and international development firm that achieves innovative solutions to health and development challenges through high-quality, cost-effective programs and research management services. We combine our proven systems with today's most effective, evidence-based best practices. Our core practice areas include: clinical research; vaccine research, microbiology and infectious disease research, development and production; biodefense; global health security; and HIV/AIDS programs. Our employees enjoy a collegial environment where individual contributions matter at all levels. At CAMRIS, you will notably improve the lives of people at home and abroad. Responsibilities Plan and execute a wide range of complex procedures and techniques including, aseptic cell culture, molecular biology (DNA/RNA isolation, cloning, analysis, purification, Illumina next generation sequencing, RNAseq through single cell SMARTseq, 10X Genomics), and cellular assays (binding and neutralization). Design and implement improved methods to existing single-cell sequencing protocols. Develop and optimize assays for diverse new projects. Conduct research including planning and conducting experiments and data analysis. Maintain and operate a variety of laboratory instruments. Collaborate with scientists from other organizations or institutions involved in similar or related research projects. Provide support and mentor to students, post-doctoral fellows and non-doctoral research technicians on experimental design and laboratory-based methodologies. Maintain accurate daily records of experiments to include the organization and archiving of research data properly. Manage project pipeline for the Vaccine Immunology Program. Maintain, operate, and optimize robotics to increase library prep throughput and sample clean-up. Integrate single cell next generation sequencing instruments (NextSeq, Miseq, 10x Chromium) to increase the project versatility of the Genome Analysis Core. Produce high quality scientific data and analysis consistently using new methods such as single cell sequencing. Analyze and interpret research data, communicate results and methods in reports, presentations, and manuscripts. Prepare presentations of research for internal data review and for external audiences. Help train post-baccalaureate IRTAs in molecular biology assays in the core. Train collaborators in molecular biology assays performed by the core. Wear appropriate Personal Protective Equipment (PPE) in a BSL-2 laboratory. Work collaboratively with team members to complete all tasks for the day but also be accountable as an individual for personal tasks. Utilize various laboratory equipment such as Biological Safety Cabinet (BSC), centrifuge, pipettes, liquid nitrogen tank, and others. Perform basic equipment maintenance as needed. Write and revise SOPs within VIP's electronic database. Performs other duties as assigned. Qualifications Master's degree in Biology, Life Sciences, or a related discipline. Two (2) years of specialized experience plus a BA/BS degree is equivalent to a Master's degree. Minimum of five (5) years of experience in biology or a related field including cell and molecular biology, immunology, and/or next generation sequencing. Experience with complex procedures and techniques including but not limited to aseptic cell culture, molecular biology, and cellular assays: Specifically with DNA/RNA isolation, cloning, purification, Illunina net generation sequencing, RNAseq through single cell SMARTseq, and 10X Genomics. Experience maintaining and operating a variety of laboratory instruments. Strong communication skills. Ability to work well with others and independently. Physical Requirements: The physical requirements described here are representative of those that must be met by a candidate to perform the essential functions of this job. Reasonable accommodations may be provided to enable individuals with disabilities to perform essential job functions. Ability to lift or carry less than 25 pounds, lift or carry 25 - 50 pounds, push or pull less than 25 pounds, push or pull 25 - 45 pounds, reach above shoulder level, and use both hands. Will be required to stand or walk more than 25 of 30 min. Must have depth perception, ability to distinguish basic colors, and perform repetitive activities. Ability to work alone and closely with others, work on shifts, and work with solvents. Will be required to be in contact with human blood or other body fluids. Will have contact with HIV-1, HIV-2, MMR viruses, and Varicella virus. Will work with aerosols, biological inhalants, corrosive substances, plastics, and solvents. Must be able to wear personal protective equipment (PPE), including gloves, face shields/goggles, safety glasses, lab coat, and disposable dust/surgical mask. Please submit your resume online at ************** . CAMRIS is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran status, disability status, or any other characteristic protected by any applicable federal, state, or local law. CAMRIS offers a comprehensive benefits package, including medical, dental, and vision insurance for individuals and families, FSAs, HSA, life and AD&D insurance, short- and long-term disability, legal services, voluntary hospital indemnity, critical illness and accident insurances, EAP, pet insurance, 401(k) with employer match and Roth option, tuition and professional reimbursement, public transportation support in the DMV area, a referral bonus program, vacation with tenure-based increases, PTO, 11 paid holidays, paid bonding leave, and paid supplemental short-term disability. Employment is contingent upon successful completion of a Public Trust-level background check, a requirement for this position under an active federal contract. The background check process may include, but is not limited to the following: (1) contacting your professional references; (2) verification of previous employment, education and credentials; (3) a criminal background check; (4) use/abuse of federally-controlled substances; and (5) a department of motor vehicle check. Candidates must be prepared to fully-complete any required background check questionnaire during initial onboarding.
    $77k-114k yearly est. Auto-Apply 5d ago

Learn more about associate scientist jobs

How much does an associate scientist earn in Leesburg, VA?

The average associate scientist in Leesburg, VA earns between $46,000 and $97,000 annually. This compares to the national average associate scientist range of $53,000 to $109,000.

Average associate scientist salary in Leesburg, VA

$67,000

What are the biggest employers of Associate Scientists in Leesburg, VA?

The biggest employers of Associate Scientists in Leesburg, VA are:
  1. Microbac Laboratories
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