Associate scientist jobs in San Marcos, CA - 450 jobs

A biopharmaceutical company in San Diego seeks a Principal Scientist to lead an in vitro pharmacology team. Candidates should have a Ph.D. and over 8 years in drug discovery, particularly with GPCRs. Responsibilities include designing assays, managing a team, and collaborating on research projects. The competitive salary ranges from $158,000 to $197,000, with comprehensive benefits including health insurance and PTO. #J-18808-Ljbffr

Come join our collaborative and creative group of AI scientists and machine learning engineers and build models that directly affect hundreds of thousands of our customers. In this role you will be building and deploying machine learning models using both analytical algorithms and deep learning approaches. We are waiting for you to join us and do the best work of your life. Responsibilities Practices excellent leadership and communication skills to influence and lead teams and to evangelize AI science across the organization Leads team's work in one or more of: ML, NLP, Statistics, or Optimization, performs hand-on work in these domains. Weighs ROI considerations of general and tailored capabilities for projects in the team Creates new capabilities that solve critical business problems Pushes the boundaries of ML by developing foundational methods and novel applications from state-of-the-art ML technologies and industry trends Influences business leaders to shape mission critical projects Creates multi-year vision that connects product strategy with technology strategy Drives architecture decisions, influences and contributes to ML platform architecture and strategy Leads team and partners to the successful delivery and integration of ML solutions Conducts design reviews, holds teams to technical and operational rigor Acts as an advisor in overseeing and mentoring the work of colleagues towards the building of a vibrant practice community Pay offered is based on factors such as job-related knowledge, skills, experience, and work location. To drive ongoing pay equity for employees, Intuit conducts regular comparisons across categories of ethnicity and gender. Qualifications PhD/MS in Engineering Mathematics, Statistics, Theoretical/Computational Physics, or related field Solid knowledge of statistical techniques 3+ years as either a lead in a AI science role or in a management position in AI science Strong communication skills and proven experience as an influencer at the executive level Hands-on programming experience and expert knowledge in one or more of: ML, NLP, Statistics, or Optimization 6+ years' experience manipulating large datasets and using databases (e.g. R, SQL, S-Plus, etc.) 6+ years' experience with a general-purpose programming language (e.g. Python, Scala, etc.) Expert knowledge and hands-on experience with ML pipelines, processes, and design patterns Proven track record of influencing business leaders to shape mission critical projects Proven track record of leading team to successful delivery of ML solutions Strong interpersonal and communication skills in order to effectively contribute to technical teams and make presentations to a variety of technical and business personnel Intuit provides a competitive compensation package with a strong pay for performance rewards approach. This position will be eligible for a cash bonus, equity rewards and benefits, in accordance with our applicable plans and programs (see more about our compensation and benefits at Intuit : Careers | Benefits). Pay offered is based on factors such as job-related knowledge, skills, experience, and work location. To drive ongoing fair pay for employees, Intuit conducts regular comparisons across categories of ethnicity and gender. The expected base pay range for this position is: Southern California, CA: $237,000 - $320,500 #J-18808-Ljbffr

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at*************** Follow @abbvie onX,Facebook,Instagram,YouTube,LinkedInandTik Tok. Job Description Discovery Biotherapeutics and Genetic Medicine (BGM) at AbbVie is seeking a highly motivated Principal Scientist to join the Biotherapeutics group at the AbbVie Bay Area (ABA) site based in South San Francisco, CA. This role seeks a skilled and experienced individual to contribute to and lead therapeutic programs, focusing on biophysical screening to advance biotherapeutics from early exploration through lead identification and optimization. Close partnerships with Oncology will be required to drive transformative ideas to the clinic. The ideal candidate must possess expertise in high-throughput biologics screening and characterization methods (e.g. ELISA, FACS, BLI, SPR, etc.) and have a solid foundation in protein sciences and antibody discovery with a proven ability to work effectively on cross-functional teams. Responsibilities Lead from the lab to advance large molecule biologics projects from exploratory to optimization stages and drive Go / No Go decisions. Effectively partner with functional and therapeutic areas to achieve project objectives. Identify and integrate cutting-edge technologies and methodologies into screening and assay development, anticipating future trends in drug discovery. Multitask and work within timelines while maintaining a high level of productivity. Supervise 1-2 scientists, evaluate team performance, and is accountable for the effective performance of team. Qualifications BS, MS, or PhD with typically 14+ (BS), 12+ (MS), or 6+ (PhD) years of relevant experience. Experience with biologics, monoclonal antibodies and/or protein therapeutics. Experience advancing Discovery programs from exploratory to candidate nomination. Independently develop and execute biosensor and cell-based platforms to evaluate panels of antibody biotherapeutics. Implement high-throughput epitope binning for large panels of monoclonal antibodies and develop deep knowledge of antibody sequence/function relationships. Evaluate and integrate biomolecular interaction technologies (e.g., SPR) to guide therapeutic candidate selection recommendations. Expert in biophysical characterization instrumentation and methodologies such as SEC, MS, HDX-MS, X-ray crystallography, DSF, DLS, etc. Challenge the status quo and onboard cutting-edge technologies to drive discovery and innovation. Excellent attention to detail, record keeping, and organization. Excellent communication, presentation, and collaboration skills. Preferred Qualifications Antibody sequence and structure knowledge. Structure-based molecular modeling and applications with AI/ML and integrating complex datasets to drive data-based decisions. CRO and external partner management. Additional Information Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future. We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees. This job is eligible to participate in our short-term incentive programs. This job is eligible to participate in our long-term incentive programs. Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company's sole and absolute discretion, consistent with applicable law. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico only - to learn more, visit ************************************************************************* US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: ************************************************************* #J-18808-Ljbffr

Genesis Molecular AI is assembling a world-class computational chemistry team to revolutionize drug discovery through cutting-edge machine learning and biophysical simulation. We are seeking a Principal CADD Scientist to join our team, working directly with scientists in our state-of-the-art wet lab and with our distributed computational chemistry and CADD science teams across the US. What You Will Do (Key Responsibilities) Utilize a combination of industry-standard and proprietary AI-powered CADD tools to guide small molecule drug discovery programs across a diverse target portfolio, including novel targets with limited chemical precedents. Use approaches like virtual screening, molecular simulation, and potency and ADMET prediction to support key decision-making in drug discovery efforts. Collaborate closely with medicinal chemists in molecular design and the development of project-specific computational approaches. Act as a cross-team connector, effectively communicating between our computational chemistry and medicinal chemistry teams to ensure seamless information flow and collaborative decision making. Adapt to a fast-paced environment where innovation and quick iteration are encouraged. What you'll bring PhD in Computational Chemistry, Structural Biology, or a related field. This particular role may also be suitable for PhD-level scientists with degrees in organic or medicinal chemistry with extensive experience in the lab, who have transitioned into industry roles in CADD. Deep understanding of structure-based drug design and protein-ligand interactions. Proficiency with industry-standard CADD tools such as MOE, PyMOL, and Schrodinger Suite. Minimum of 5+ years of industry experience as a CADD scientist in pharma or biotech, with hands-on experience in active drug discovery programs. Onsite in our San Diego lab is preferred for this role, to be able to collaborate with our scientists. We are open to remote team members too. What we offer Competitive Pay Health Care Plans (including Medical, Dental, and Vision, fully covered for the employees) Stock Option Eligibility 401(k) Plan Open PTO Policy Paid Company Holidays Subsidized lunch and snacks at our offices Genesis Molecular AI is pioneering foundation models for molecular AI to unlock a new era of drug design and development. The company's generative and predictive AI platform, GEMS (Genesis Exploration of Molecular Space), integrates AI and physics into industry-leading models to generate and optimize drug molecules, including the breakthrough generative diffusion model Pearl for structure prediction. Genesis has raised over $300 million from leading AI, tech and life science-focused investors, signed multiple AI-focused research collaborations with major pharma partners, and is deploying GEMS to advance an internal therapeutics pipeline for a variety of high-impact targets. Genesis is headquartered in Burlingame, CA, with a fully integrated laboratory in San Diego. We are proud to be an inclusive workplace and an Equal Opportunity Employer. #J-18808-Ljbffr

A global healthcare company based in San Diego is looking for an experienced scientist to lead biologics discovery and development. This role involves working cross-functionally with Immunology teams and external partners to innovate therapeutics focusing on antibodies and multicentric projects. Candidates should possess a strong background in protein therapeutics with respective educational qualifications and experience. A commitment to diversity and inclusion within the workplace is essential. #J-18808-Ljbffr

A leading global healthcare firm in San Diego is seeking a highly motivated scientist to contribute to biotherapeutics development. The successful candidate will discover and engineer antibodies, oversee experiments, and utilize various molecular biology techniques. Applicants should have at least 6 years of relevant experience and a strong background in flow cytometry. This position offers competitive compensation ranging from $110,250 to $187,000 along with comprehensive benefits. #J-18808-Ljbffr

• Primarily responsible for commercial manufacturing. Also responsible for the transfer of manufacturing processes from R&D to Manufacturing and continuous improvement of existing processes. Essential Duties and Responsibilities The incumbent may be asked to perform other function-related activities in addition to the below mentioned responsibilities as reasonably required by business needs. • Maintains the Pilot Plant laboratory under cGMP conditions. • Produces development, pilot, and production materials per written instructions. • Completes ERP transactions. • Stocks and maintains the laboratory supplies. • Keeps accurate records and documentation. • Completes laboratory work and associated paperwork by assigned completion dates. • Produces notebook materials per written instructions. • Develops manufacturing processes for transfer to Manufacturing. • Assists with execution of process validation of new and existing manufacturing processes. • Improves manufacturing processes. • Completes cycle counts. • Washes lab ware. Qualifications Education • Bachelor's degree (sciences) Experience • 1+ years' experience preferred Skills • Basic knowledge of QMS (Quality Management System)/GMP requirements Must follow all applicable FDA regulations and ISO requirements.

In Vivo Research Associate II/III, Large Animals (Contract to Hire) Looking to hone your animal surgery skills? One of San Diego's leading biotech companies is looking for a competent, reliable Research Associate to add to their dynamic team. This role offers the opportunity to build upon the foundation you've already laid in your industry experience and refine your in-vivo surgical skills. Don't miss this rare opportunity to learn from top professionals, grow into a more senior role, and excel in a challenging and supportive environment. What you will do: Administer test substances by various dosing methods, perform catheter placements, and prepare study activities. Manage and observe animals pre/post-surgery for general health and well-being. Collection of biological specimens including but not limited to skin, tissue, and blood from all animal species onsite. Who you are: AS OR BS with at least 4 years of experience with medical device studies or similar. Must have experience handling large animals (pigs, sheep, goats, rabbits, etc) Experience with dosing/injections (IM, SubQ, IV, IP, oral) Experience in a surgical environment is preferred. What does this position pay? Compensation is determined by several factors which may include skillset, experience level, and geographic location. The expected range for this role is $28.00 to $35.00 per hour. Please note this range is an estimate and actual pay may vary based on qualifications and experience. Please email your resume to sshields@provenrecruiting.com if you'd like to work alongside some of the finest professionals in the Life Sciences industry! Note: We actively support and promote people of various backgrounds, from race, religion, gender to geographical area, university, lifestyle, and personality type. Proven Recruiting is minority-owned, majority women, and is a strong advocate for diversity and inclusion in the broader community. Apply today!

**Be visionary** Teledyne Technologies Incorporated provides enabling technologies for industrial growth markets that require advanced technology and high reliability. These markets include aerospace and defense, factory automation, air and water quality environmental monitoring, electronics design and development, oceanographic research, deepwater oil and gas exploration and production, medical imaging and pharmaceutical research. We are looking for individuals who thrive on making an impact and want the excitement of being on a team that wins. **Job Description** **Job Summary:** TAPI is seeking a highly experienced Scientist, with a proven record of developing Gas Chromatography Instrumentation, to join our Research and Development team. This role will focus on the development of new GC-based instrumentation to support innovation in analytical chemistry and production workflows. The ideal candidate will bring deep expertise in gas chromatography, method development, and instrumentation, along with a strong background in production or R&D environments. **Key Responsibilities** + Lead the design and development of advanced gas chromatography (GC) methods and instrumentation. + Operate, maintain, and troubleshoot GC instruments including FID, DBD, FPD, and PID detectors. + Collaborate with cross-functional teams to support product development and quality assurance. + Perform sample preparation, calibration, and quantitative analysis with high precision. + Document and validate analytical methods in compliance with internal and regulatory standards. + Mentor junior technicians and contribute to technical training initiatives. + Communicate findings clearly through technical reports and presentations. **Minimum Qualifications** Education: Bachelor of Science (B.Sc.) in Chemistry, Biochemistry, Analytical Chemistry, or a related scientific field. Experience: Minimum of 10 years of relevant work experience in a R&D or Manufacturing environment. Technical Expertise: - Proficiency in GC method development, validation, and troubleshooting. - Proven experience with GC instruments including FID, DBD, FPD, and PID. - Familiarity with chromatography data systems such as Chromperfect . - Strong understanding of sample preparation, calibration, and quantitative analysis. Soft Skills: - Exceptional analytical thinking and attention to detail. - Excellent written and verbal communication skills. **Preferred Qualifications** + Experience in developing GC technologies for novel applications. + Knowledge of regulatory standards and documentation practices (e.g., cGMP, SOPs). + Ability to work independently and manage multiple projects simultaneously. **Why Join TAPI?** At TAPI, you'll be part of a dynamic team driving innovation in analytical science. We offer competitive compensation, a collaborative work environment, and opportunities for professional growth. **Salary Range:** $113,600.00-$151,400.000 **Pay Transparency** The anticipated salary range listed for this role is only an estimate. Actual compensation for successful candidates is carefully determined based on several factors including, but not limited to, location, education/training, work experience, key skills, and type of position. Teledyne conducts background checks on qualified applicants who receive a conditional offer of employment in accordance with applicable laws, regulations and ordinances. Background checks may include, but are not limited to, education verification, employment history and verification, criminal convictions, Motor Vehicle Report (MVR & driving history), reference check, credit checks/credit history and drug testing. All qualified applicants with arrest or conviction records will be considered for employment in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act. Teledyne and all of our employees are committed to conducting business with the highest ethical standards. We require all employees to comply with all applicable laws, regulations, rules and regulatory orders. Our reputation for honesty, integrity and high ethics is as important to us as our reputation for making innovative sensing solutions. Teledyne is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status, age, or any other characteristic or non-merit based factor made unlawful by federal, state, or local laws. You may not realize it, but Teledyne enables many of the products and services you use every day **.** Teledyne provides enabling technologies to sense, transmit and analyze information for industrial growth markets, including aerospace and defense, factory automation, air and water quality environmental monitoring, electronics design and development, oceanographic research, energy, medical imaging and pharmaceutical research.

Job Description Our client, a fast-growing leader in the functional food, supplement, and wellness ingredient industry, is seeking an accomplished R&D Scientist to drive innovation and scientific excellence across their ingredient portfolio. This individual will play a critical role in developing, optimizing, and validating ingredient processes and analytical methods to advance the potency, consistency, and bioavailability of natural, bioactive compounds. This position is ideal for a technically driven and entrepreneurial scientist who thrives in a collaborative environment, excels at translating scientific insights into commercial outcomes, and is passionate about functional nutrition and wellness innovation. The R&D Scientist will lead research and development initiatives focused on ingredient optimization, analytical method development, and bioactive compound testing. Partnering closely with cross-functional teams-including Quality, Mycology, and Operations-this individual will support the full lifecycle of ingredient innovation, from discovery through commercialization. The successful candidate will be hands-on, organized, and capable of managing multiple complex projects simultaneously, while fostering a culture of scientific curiosity, precision, and accountability. **This is a hybrid position must onsite at least 3 days a week in San Diego, CA. Key Responsibilities Develop and optimize analytical and testing methods to support ingredient characterization and functional performance. Design and validate finished product specifications related to nutritional and bioactive properties. Partner with external laboratories and contract research organizations to conduct analytical testing and ensure data quality. Drive new ingredient development projects, including feasibility assessments, process optimization, and product qualification. Collaborate cross-functionally to ensure projects meet technical, regulatory, and commercial readiness milestones. Provide scientific input and data to support patent filings and intellectual property development. Support investigations related to food safety, quality, and testing accuracy in partnership with internal QA/FSQA teams. Contribute scientific insights and innovative concepts that expand the R&D and innovation pipeline. Qualifications Master's degree (M.Sc.) or higher in Chemistry, Biochemistry, Food Science, or a related scientific field. 5+ years of experience in R&D, product development, or analytical science within the functional ingredients, dietary supplement, or food industry. Experience with analytical methods such as mass spectrometry, chromatography, DNA sequencing, or immunoassays is strongly preferred. Proven experience collaborating with external laboratories or CROs. Strong technical writing, data interpretation, and presentation skills. Ability to manage multiple complex projects in a fast-paced, dynamic environment. Creative, detail-oriented, and motivated by scientific discovery and product excellence. This is an exciting opportunity to join a mission-driven organization at the forefront of functional ingredient innovation-combining science, sustainability, and wellness to shape the next generation of food and nutrition solutions. If you are an experienced R&D scientist seeking to make a meaningful impact in a rapidly growing segment of the health and wellness industry, we'd love to connect with you. Compensation: $120,000 - $140,000plus benefits If this sounds like the position you have been waiting for, please apply using the online application or the link below - all inquiries are strictly confidential. Our focus is to assist you to make your best next career move, and we will not use your information for any other purpose. Kalon Search is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status. *******************

STA Pharmaceuticals, a WuXi AppTec Company, has an exciting opportunity for a Process Research and Development Scientist in our San Diego site. This position works within a team of Process Research and Development (R&D) Scientists in conjunction with the Analytical Chemistry Department and is co-responsible for developing safe, efficient and easily scalable processes for producing starting materials, intermediates and active pharmaceutical ingredients (APIs). In addition, this position assists in tech transferring projects to Kilo Lab and Pilot Plant scales and contributes to the safe and cGMP compliant execution of API manufacturing processes. This is a hands-on synthetic organic chemistry role that requires the ability to solve process and scale-up problems through laboratory-scale investigations of organic synthesis reactions and separations. The incumbent may also work with Quality Assurance (QA) to ensure that high quality standards are maintained and appropriate documentation such as process development and scale-up documentation, including batch records (BRs) are completed in a timely manner, and that standard operating procedures (SOPs) are written and followed. Responsibilities • Researches and develops fit for purpose, safe, efficient and easily scalable chemical processes to make SM, API, intermediates. • Reports project progress to the supervisor and the clients to ensure that timelines and expectations are delivered. • Plans, executes, and documents cGMP and Non-GMP/GLP laboratory work supporting regulatory submissions. • Evaluates chemical reactivity hazards using techniques, such as reaction calorimetry, online analytics, and batch process modeling tools. • Collaborates with other functional groups as needed. • Coordinates the completion of specific project tasks with other departments. • Actively communicates, consults and collaborates with colleagues and clients to ensure optimal execution and record of PR&D activities. • Provides regular updates, documentation and communication of PR&D results to development team/clients. • Collates and presents results in various forms, such as weekly/monthly reports, technical reports, and oral presentations for internal review and to clients Qualifications • PhD in synthetic organic chemistry or related field, relevant experience, or equivalent combination of education and industry experience is preferred. • Strong background in organic chemistry, as well as thorough knowledge of analytical techniques. • Synthetic organic chemistry such as rational design of reaction, synthetic routes, mechanism understanding/elucidation. Experience in total synthesis is a plus. Knowledge / Skills / Abilities: • Demonstrated in-depth understanding of organic synthesis, purification techniques, and analysis of organic reactions/products. • Demonstrated success working effectively outside defined scope of responsibility, when required. • Ability to provide technical and troubleshooting support for all Process R&D activities. Anticipated salary range: $82,731 to $120,000 An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability We can recommend jobs specifically for you! An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability Click here to get started.

Universal Sequencing Technology, a biotech startup headquartered in Canton, MA (~15 miles southwest of Boston) with a location in Carlsbad, CA, is looking for a highly talented Manufacturing Scientist to join the team, located in Carlsbad, CA.* We are excited to provide novel DNA sequencing technology for the Next Generation Sequencing (NGS) platforms that enables many previously unachievable applications. This position is a unique opportunity to commercialize a novel NGS library technology, TELL-Seq TM , an ultra-low input single tube linked read technology which enables many previously unachievable long read applications and to develop disruptive single cell applications. The incumbent will have hands on experience on DNA conjugation and amplification, in-process quality control assay development, filling and labeling experience and capability to increase scalability using technology, equipment, manpower, etc… to meet increasing demand. S/He will work closely with R&D and manufacturing teams to scale up production procedure and accelerate product commercialization. S/He must have excellent documentation skills and strong interpersonal skills, be driven by making high quality products, and enjoy working in a multi-disciplinary environment. Key Responsibilities Engineer scale up procedures for bulk production, filling process and kit assembly Optimize reagent formulation and process for bulk DNA amplification in emulsions Develop in-process quality control assays (analytical) for reagent formulations, productions, characterization and identification Execute well thought out experiments, record results accurately along with in-depth analysis and reports that will be reviewed, approved and filed in QA Create/update manufacturing production protocols, execute protocol and/or train others to do the same Work with other manufacturing personnel to make bulks, fill reagents and assemble kits. This is a hands on, in the lab position Work with Inventory Management to ensure proper handling, storage, usage and accountability of all materials needed to produce or test products Manage and execute stability sampling, storage and testing Manage tasks, projects and timeline to meet deliverable on time and on quality. Manage resources accordingly for the same Write, review and revise SOP's through a Document Change Order. Initiates, Investigates and write up non-conformance reports. Required Skills and Background M.Sc. or Ph.D. in chemistry, chemical engineering, molecular biology, biochemistry, biology, biotechnology or a similar field (B.S. with exceptional experience WILL be considered) Prior GMP and GDP experience is required. Hands on experience with magnetic beads (suspension material), oligo conjugation and quantification Direct experience in nucleic acid amplification technologies, particularly in emulsion PCR Experience in Lean Six Sigma project implementation is a plus 5-7 years experience in a reagent GMP environment Detail oriented and very good documentation skill Hands on leaders perform well in this environment

Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing. Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates. Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need. The Position Arrowhead is seeking a highly motivated Associate Scientist to join our growing Discovery Chemistry team at our San Diego site. This individual will primarily focus on oligonucleotide bioconjugation, peptide synthesis, purification, and analytical chemistry. As a discovery chemist, you will play a key role in the development and optimization of si RNA-based therapeutics by applying your expertise in bioconjugation strategies and peptide chemistry. Responsibilities Maintain a well-documented laboratory notebook Track progress against project timelines, generate regular status updates, and communicate progress and issues to management Perform tasks across projects Manage time effectively to meet deadlines Adhere to safe laboratory practices Prioritize and perform synthesis, purification, and analysis of conjugates based on project deliverable timelines Requirements: B.S. or M.S. Chemistry or Biochemistry degree with excellent understanding of organic and analytical chemistry 0-3 years of experience working in a chemistry laboratory Experience with a wide range of analytical techniques, especially HPLC Ability to quickly learn new procedures and techniques Preferred: Experience working with large-molecule synthetic targets, particularly oligonucleotides, in an academic or industry setting Experience with solid-phase peptide synthesis (automated and/or manual) Prior experience in a pharmaceutical or biotechnology environment California pay range $60,000-$80,000 USD Arrowhead provides competitive salaries and an excellent benefit package. All applicants must have authorization to work in the US for a company. California Applicant Privacy Policy

Scientist, Protein Production and Characterization AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab Mouse suite of transgenic mice. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science. We are seeking a highly motivated and skilled Scientist to join our Protein Sciences team and contribute to both day-to-day operations and the advancement of Protein Science workflows. This position will focus on the design, optimization, and execution of transient transfection processes at various scales for antibody and protein production in mammalian expression systems. The successful candidate will leverage expertise in biophysical characterization and biochemical modification to evaluate key protein attributes. This position will report to the Associate Director of Protein Sciences and work closely with scientists in the Antibody Discovery, Antibody Engineering, Protein Sciences, and Project Management teams. The ideal candidate will drive innovation through process refinement, high-throughput automation, and growing proficiency of chemical conjugation techniques. This role offers the opportunity to work in a fast-paced, collaborative research environment, where creative solutions and a strong scientific approach are key to success. Responsibilities Responsibilities: Independently design, plan, and execute transient transfection workflows for antibody and protein production across various mammalian expression systems Develop, design, and optimize protein purification methods to enhance throughput, quality, and efficiency, as required Lead developability assessment studies by designing and conducting analytical experiments to evaluate protein stability, purity, and key biophysical characteristics Support production of complex construct design strategies (e.g VLPs, nanodiscs etc.), to enable immunization antibody discovery campaigns against challenging targets Drive implementation of automated high throughput processes to support protein production workflows using Bravo, and other robotic systems Maintain meticulous experimental records using electronic notebook (Benchling), and communicate results clearly through written reports and presentations to support project progression and scientific decision-making Contribute innovative ideas and collaborate effectively across teams to foster research excellence and ensure project success in a fast-paced environment Qualifications Qualifications: Ph.D. in Biochemistry, Chemistry, Molecular Biology, Protein Engineering, or a related field with a minimum of 2 years of industry experience or MS with minimum of 6 years of direct industry experience is required Proven hands-on experience with multiple mammalian expression platforms is required Proficiency with AKTA instrumentation, and a broad range of purification techniques, including affinity chromatography, ion exchange, HIC, and SEC, as well as standard protein QC methodologies is required Experience with therapeutic antibody developability assessment is highly desirable Strong analytical, troubleshooting, and communication skills with exceptional attention to detail Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation About AlivaMab Biologics AlivaMab Biologics sets its partners' antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners' design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team's experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab Mouse platforms, ensure the highest probability of success. The salary range for this position considers various factors, including skills, experience, training, certifications, and organizational needs. Note that this range does not reflect any geographic adjustments based on the location where the role will be based. At AlivaMab Biologics, it is uncommon for a new hire to start at or near the top of the salary range, as compensation is tailored to each individual's skills and breadth and depth of experience. The current estimated range is $98,500 - $140,000, plus a bonus target, benefits, and equity. AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. #LI-DNI

Scientist, Protein Production and Characterization AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab Mouse suite of transgenic mice. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science. We are seeking a highly motivated and skilled Scientist to join our Protein Sciences team and contribute to both day-to-day operations and the advancement of Protein Science workflows. This position will focus on the design, optimization, and execution of transient transfection processes at various scales for antibody and protein production in mammalian expression systems. The successful candidate will leverage expertise in biophysical characterization and biochemical modification to evaluate key protein attributes. This position will report to the Associate Director of Protein Sciences and work closely with scientists in the Antibody Discovery, Antibody Engineering, Protein Sciences, and Project Management teams. The ideal candidate will drive innovation through process refinement, high-throughput automation, and growing proficiency of chemical conjugation techniques. This role offers the opportunity to work in a fast-paced, collaborative research environment, where creative solutions and a strong scientific approach are key to success. Responsibilities Responsibilities: * Independently design, plan, and execute transient transfection workflows for antibody and protein production across various mammalian expression systems * Develop, design, and optimize protein purification methods to enhance throughput, quality, and efficiency, as required * Lead developability assessment studies by designing and conducting analytical experiments to evaluate protein stability, purity, and key biophysical characteristics * Support production of complex construct design strategies (e.g VLPs, nanodiscs etc.), to enable immunization antibody discovery campaigns against challenging targets * Drive implementation of automated high throughput processes to support protein production workflows using Bravo, and other robotic systems * Maintain meticulous experimental records using electronic notebook (Benchling), and communicate results clearly through written reports and presentations to support project progression and scientific decision-making * Contribute innovative ideas and collaborate effectively across teams to foster research excellence and ensure project success in a fast-paced environment Qualifications Qualifications: * Ph.D. in Biochemistry, Chemistry, Molecular Biology, Protein Engineering, or a related field with a minimum of 2 years of industry experience or MS with minimum of 6 years of direct industry experience is required * Proven hands-on experience with multiple mammalian expression platforms is required * Proficiency with AKTA instrumentation, and a broad range of purification techniques, including affinity chromatography, ion exchange, HIC, and SEC, as well as standard protein QC methodologies is required * Experience with therapeutic antibody developability assessment is highly desirable * Strong analytical, troubleshooting, and communication skills with exceptional attention to detail * Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation About AlivaMab Biologics AlivaMab Biologics sets its partners' antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners' design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team's experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab Mouse platforms, ensure the highest probability of success. The salary range for this position considers various factors, including skills, experience, training, certifications, and organizational needs. Note that this range does not reflect any geographic adjustments based on the location where the role will be based. At AlivaMab Biologics, it is uncommon for a new hire to start at or near the top of the salary range, as compensation is tailored to each individual's skills and breadth and depth of experience. The current estimated range is $98,500 - $140,000, plus a bonus target, benefits, and equity. AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. #LI-DNI

Scientist, Protein Production and Characterization AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab Mouse suite of transgenic mice. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science. We are seeking a highly motivated and skilled Scientist to join our Protein Sciences team and contribute to both day-to-day operations and the advancement of Protein Science workflows. This position will focus on the design, optimization, and execution of transient transfection processes at various scales for antibody and protein production in mammalian expression systems. The successful candidate will leverage expertise in biophysical characterization and biochemical modification to evaluate key protein attributes. This position will report to the Associate Director of Protein Sciences and work closely with scientists in the Antibody Discovery, Antibody Engineering, Protein Sciences, and Project Management teams. The ideal candidate will drive innovation through process refinement, high-throughput automation, and growing proficiency of chemical conjugation techniques. This role offers the opportunity to work in a fast-paced, collaborative research environment, where creative solutions and a strong scientific approach are key to success. Responsibilities Responsibilities: Independently design, plan, and execute transient transfection workflows for antibody and protein production across various mammalian expression systems Develop, design, and optimize protein purification methods to enhance throughput, quality, and efficiency, as required Lead developability assessment studies by designing and conducting analytical experiments to evaluate protein stability, purity, and key biophysical characteristics Support production of complex construct design strategies (e.g VLPs, nanodiscs etc.), to enable immunization antibody discovery campaigns against challenging targets Drive implementation of automated high throughput processes to support protein production workflows using Bravo, and other robotic systems Maintain meticulous experimental records using electronic notebook (Benchling), and communicate results clearly through written reports and presentations to support project progression and scientific decision-making Contribute innovative ideas and collaborate effectively across teams to foster research excellence and ensure project success in a fast-paced environment Qualifications Qualifications: Ph.D. in Biochemistry, Chemistry, Molecular Biology, Protein Engineering, or a related field with a minimum of 2 years of industry experience or MS with minimum of 6 years of direct industry experience is required Proven hands-on experience with multiple mammalian expression platforms is required Proficiency with AKTA instrumentation, and a broad range of purification techniques, including affinity chromatography, ion exchange, HIC, and SEC, as well as standard protein QC methodologies is required Experience with therapeutic antibody developability assessment is highly desirable Strong analytical, troubleshooting, and communication skills with exceptional attention to detail Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation About AlivaMab Biologics AlivaMab Biologics sets its partners' antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners' design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team's experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab Mouse platforms, ensure the highest probability of success. The salary range for this position considers various factors, including skills, experience, training, certifications, and organizational needs. Note that this range does not reflect any geographic adjustments based on the location where the role will be based. At AlivaMab Biologics, it is uncommon for a new hire to start at or near the top of the salary range, as compensation is tailored to each individual's skills and breadth and depth of experience. The current estimated range is $98,500 - $140,000, plus a bonus target, benefits, and equity. AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. #LI-DNI

Research Biologist needs 1 or more years of research experience in an academic institute, biotechnology or pharmaceutical industry Research Biologist requires: Bachelors degree in biology, biochemistry, molecular biology or similar discipline with 1 or more years of research experience in an academic institute, biotechnology or pharmaceutical industry Experience in running biochemical and immunological assays. Highly motivated and agile biochemist Research Biologist duties: Perform experiments to characterize protein-protein interactions using PAGE, Western Blot, ELISA & SPR technologies Perform basic tasks to support tissue culture and maintenance of immune competent cell lines Perform basic cell-based assays with immunology research-related technologies (e.g. human whole blood, primary human leukocyte isolation, cellular activation and differentiation, FACS, cytokine assay, etc.) Work with a cross-disciplinary team for data analysis Independently execute experiments, analyze, interpret and present experimental data

A leading biopharmaceutical company in San Diego is seeking a highly motivated Principal Scientist to lead therapeutic programs in biotherapeutics. The ideal candidate must possess expertise in high-throughput biologics screening and have a solid foundation in protein sciences and antibody discovery. Key responsibilities include advancing biologics projects, partnering with functional areas, and mentoring a small team of scientists. The role requires excellent communication skills and a strong track record in drug discovery. #J-18808-Ljbffr

A global healthcare leader in San Diego seeks a highly motivated scientist to contribute to the discovery and development of biotherapeutics. The role involves discovering and optimizing antibodies, utilizing flow cytometry, and requires strong skills in molecular biology and biochemistry. Ideal candidates should have significant industry experience and be detail-oriented, with excellent communication skills. Competitive compensation and benefits include a flexible benefits package and bonus potential. #J-18808-Ljbffr