Berkshire Medical Center Remote jobs - 278 jobs

The Director of Financial Planning and Analysis, Biopharmaceutical Sciences and Manufacturing Operations (BSMO) is a key member of Vertex's Financial Planning & Analysis team. This role will partner closely with Commercial Manufacturing and Tech Ops (CMTO), Commercial Finance and Disease Strategy Team (DST) Finance in support of our Cell and Gene Therapies portfolio, with a specific focus on CASGEVY, the first-ever approved CRISPR-based gene-editing therapy used to treat Sickle Cell Disease and Transfusion-Dependent Thalassemia. This role will have the opportunity to work across the organization by providing analysis and insights that will drive key decisions around manufacturing strategy and resource allocation in order to optimize the profitability of CASGEVY. In addition, this position will be an integral part of the BSMO Finance team and play a key role in support of P&L, Capital and Inventory budgeting, forecasting, long range planning, and month-end close processes. This position is based in our Boston, MA location (Seaport area) and requires a hybrid work schedule with 3 days in office /2 days remote on a weekly basis. Key Duties & Responsibilities: Partners with the External Manufacturing, Supply Chain, and Commercial functions to influence CASGEVY business operations and optimize decisions as part of the Sales and Operations Planning (S&OP) process. Identifies ROI/trade-off opportunities to drive profitability and support key decisions around CASGEVY manufacturing and supply chain strategy. Oversees the monthly/quarterly accounting close for expenses and accruals related to CASGEVY Operating Expense and COGS, including flux analysis and compliance with SOX control requirements. Supports analytics and transparent reporting to drive forecast accuracy and inform on key drivers of any variances to plan, with full transparency on any judgments about risks and opportunities for both operating expenses, capital expenses and COGS. Supports the financial planning process (annual budget, forecasts, long range plan, etc.) by providing forward-looking observations and developing key scenarios. Develops and coaches team members to encourage growth and new opportunities and contributes to an atmosphere of inclusivity across the team Works closely with other members of the CFO organization including Commercial Finance, DST Finance, Strategic Sourcing and Accounting to maintain a continuous improvement mindset and promote strong communication, sharing of best practices and efficient processes. Basic Requirements Bachelor's degree in Finance or Accounting required. MBA and/or other advanced degree preferred. 10+ years of relevant experience in finance managerial role, demonstrating strong technical and analytical skills and a track record of success working in a team-based environment or the equivalent combination of education and experience. Experience in business partnering with Manufacturing/Supply Chain executive teams Proven ability to proactively manage efficient processes across Operating Expenses, Inventory and COGS, driving high-quality inputs from the business in support of creating and managing complex budgets, forecasts, and analyses in a dynamic, fast-paced environment. Deep understanding of Biotech/Pharma manufacturing finance to address a broad range of challenges and business issues across all functions with the ability to make and facilitate quick decisions Expert analytical and financial modeling skills to evaluate a broad range of financial questions. Excellent communication and presentation skills, with a proven ability to present complex financial insights to senior stakeholders. Knowledge and Skills: Strategic thinking and problem-solving. Critically, this role requires an expert ability to influence without authority at the highest level and collaborate effectively in support of shared goals. Strong business acumen and judgment, and knowledge of the company's markets/products and industry trends. Expertise with Excel and PowerPoint; Working knowledge of Hyperion or similar enterprise planning tools. Exceptional interpersonal, written, and verbal communication skills Ability to lead and drive change in an evolving business environment, coordinating processes involving large numbers of people, complex systems, and tight deadlines to deliver innovative solutions. Demonstrated ability to lead and collaborate cross-functionally, sharing insights and translating learnings into actionable business initiatives whilst partnering to ensure timely execution of project plans Proactive, organized, and comfortable managing shifting priorities in a rapidly changing environment. Leads with a continuous improvement mindset, with flexibility and ability to adapt to change. Pay Range: $182,400 - $273,600 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Job Description ARS Pharmaceuticals is a fast growing and innovative company committed to bringing novel products forward that will improve patient outcomes and lives. We recently launched neffy , an intranasal epinephrine product that can be used to halt the symptoms associated with a severe allergic reaction (SAR) which can lead to anaphylaxis and even death. This is an exciting time to make an impact here at ARS and an opportunity to transform the patient and caregiver experience. We promote a culture of inclusivity, integrity, and creativity, while pursuing solutions for patients and families affected by serious allergic reactions. JOB SUMMARY: As a field-based medical expert, the MSL supports ARS's products and therapeutic areas by advancing scientific and collaborative relationships and acting as a conduit for timely knowledge exchange with key members of external healthcare communities and internal stakeholders towards optimized patient outcomes. The MSL function in general is knowledge-based, anchored in educating internal and external stakeholders on the science behind, and safe and appropriate use of our products. The MSL supports the generation of medical-scientific knowledge and applies subject matter expertise and experience to special projects. Position covers several states in the Northeast including: NY, MA, VT, NH, and ME. Candidates must live within the region. ESSENTIAL DUTIES & RESPONSIBILITIES: Acquire and maintain a level of medical-scientific knowledge in the assigned therapeutic area(s) and/or disease state(s) related to ARS products. Accurately and compliantly interpret and disseminate balanced and factual scientific, clinical, and health economic data. Gather and evaluate new information as it applies to ARS products and areas of therapeutic interest. Leads efforts in recognizing, identifying, cultivating, and integrating KOL relationships in specific therapeutic areas of interest to ARS Commercial Operations. Identifies opportunities for scientific growth and generation of medical evidence in support and/or expansion of current utilization of therapies and execution of mutual interest initiatives such as research and continuing medical education (CME). Identifies, develops, and manages KOL relationships on a continuum of advocacy in support of company objectives and enhancing ARS's reputation as a scientifically innovative industry partner. Tactical delivery of programs according to established objectives and serves as a resource for education and dissemination of pertinent, clear, and balanced medical-scientific information to internal audiences (Marketing, Medical Affairs, Clinical research, R&D and Sales) and external audiences (healthcare professionals, consumers, patient organizations, distributors, etc.). Provide areas of interest and general high-level information regarding ARS's Investigator Study (IIS) program process in response to unsolicited requests. Monitor and communicate progress for those IISs approved and supported. EDUCATION AND EXPERIENCE: PharmD/Doctoral level degree in a medical and or scientific field preferred. RN/MSN or similar advanced degree with strong relevant experience will be considered. 3-5 years in the pharmaceutical or biotechnology industry preferred. Strong preference for experience within allergy/immunology You demonstrate outstanding knowledge of the MSL function, medical planning, and key medical expert engagement. KNOWLEDGE, SKILLS, AND ABILITIES: Ability to travel 60%-75% of time, including overnights and weekends as necessary. Customer Focus Solid interpersonal and communication skills; demonstrated relationship builder. Must have a style that promotes respect, credibility, and trust throughout the organization. Must be able to organize, prioritize, and work effectively in a dynamic, field-based environment. Demonstrated ability to work independently (Remote position). Strong presentation and writing skills. Results oriented and self-motivated. At ARS, we are proud to offer a highly competitive compensation & benefits package. The full-time salary range for this posted position is $190,000 to $225,000 and may be eligible for a discretionary annual performance bonus. Actual pay rates are determined by considering multiple factors including qualifications, relevance of experience, education & credentials, subject matter expertise, and other job-related factors permitted by law. This position is also eligible for Equity, 401k matching, and our excellent benefits package including 100% employer paid Medical, Dental & Vision for employees. View the full package here: ARS Careers Page ARS Pharmaceuticals believes in Equal Opportunity for all and is committed to ensuring all individuals, including individuals with disabilities, have an opportunity to apply for those positions that they are interested in and qualify for without regard to race, religion, color, national origin, citizenship, sex, sexual orientation, gender identity, age, veteran status, disability, genetic information, or any other protected characteristic. ARS Pharmaceuticals is also committed to providing reasonable accommodation to qualified individuals so that an individual can perform their job-related duties. If you are interested in applying for an employment opportunity and require special assistance or an accommodation to apply due to a disability, please contact us at ********************** The position will be posted until a final candidate is selected for the requisition or the requisition has a sufficient number of applications.

The Project Leadership function at Parexel is a critical part of driving success for our clients and advancing clinical research projects. As a part of the Global Project Leadership organization, your work has a direct impact on the projects, teams, and clients you work with, while helping deliver projects to the benefit of the patients we serve. Parexel's defined Biotech Division offers opportunities for seasoned Project Management professionals with a strong background running global clinical trials in a variety of therapeutics. This group focuses specifically on Biotech clients and providing all areas of support to accommodate their unique needs. This is a great opportunity for those in the industry who prefer the flexibility, creatively and problem-solving mindset to successfully support this type of clients. **Parexel has upcoming future opportunities at the Project Leader (PM) and Senior Project Leader (SPM) level for candidates with experience leading obesity global studies.** Individuals selected for these roles will provide leadership to project teams and manage the day-to-day operations while striving to achieve operational excellence through on time delivery within budget and to the highest quality with the goal to exceed client expectations Successful candidates possess an undergraduate degree in a clinical or health related field: advanced degree preferred, along with at minimum, 2+ years' experience leading Global Clinal Trials in Project Management within a CRO (preferred), Biotech or Pharma company. These positions also require experience in project scheduling, managing resources and budgets and coordinating team activities, as well as experience with the full clinical development process through regulatory submissions. Additional years of experience will be required for the more senior role of Senior Project Leader. To excel in this role, flexibility, problem solving capabilities and strategic vision are qualities that propel our Project Leadership team member's growth. In addition, you need to be detailed-oriented, computer proficient and possess superior interpersonal and organizational skills. \#LI-REMOTE EEO Disclaimer Parexel is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to legally protected status, which in the US includes race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or protected veteran status.

**Join Our Medical Communications Team at Parexel as a Senior Program Specialist (Publications)** Are you a seasoned project manager or account manager with experience in medical communications-particularly in publications? We're seeking a **Senior Program Specialist** to lead the execution of complex, multidisciplinary publication programs while driving excellence across cross-functional teams. This is a full-time, remote position that may require occasional travel. This is a full time remote position. Candidates need to work out of Canada or the continental United States. **What You'll Do** As a Senior Program Specialist, functioning as a program/project manager you will: + **Lead and facilitate program/project kick-off meetings** , establishing clear roles, responsibilities, and expectations across internal teams and external stakeholders. + **Develop and manage comprehensive project plans** , delivery schedules, and tracking systems to ensure timely, high-quality execution. + **Maintain proactive communication** with clients, faculty, and internal teams, serving as the key point of contact for project status updates and issue resolution. + **Monitor budgets, timelines, and deliverables** , identifying risks and resolving issues promptly to keep projects on track and within scope. + **Collaborate cross-functionally** to define project scope, staffing requirements, and implementation strategies, raising concerns and adjusting plans as needed. + **Support proposal development and budgeting processes** , contributing to program specifications, cost assessments, and implementation planning. + **Champion best practices** in communication, process efficiency, and team collaboration, continuously identifying opportunities for improvement and innovation. + **Ensure alignment with strategic goals and product messaging** , working closely with Account Managers/Directors and functional teams to deliver impactful solutions. **What You Bring** + Must have 5+ years experience in medical communications project management, (Publications). + Proven ability to lead teams and deliver projects on time and within budget. + Strong organizational, negotiation, and interpersonal communication skills. + Advanced proficiency in Microsoft Word, PowerPoint, Excel, Outlook, and database tools. + iEnvision experience is required. + Familiarity with publication guidelines (e.g. ICMJE). + Bachelor's degree required; Master's preferred in Business or Life Sciences. **Why You'll Love Working Here** + Be part of a collaborative and innovative team. + Work on impactful healthcare and scientific programs. + Enjoy a flexible work environment with growth opportunities. **Ready to make a difference?** Apply today and bring your expertise to a team that values excellence, innovation, and collaboration. \#LI-REMOTE EEO Disclaimer Parexel is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to legally protected status, which in the US includes race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or protected veteran status.

For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we'll help you build a career that you can feel passionate about. **Job Summary** As a Sales Development Representative (SDR), you will be a critical part of the Charles River commercial team. Your primary mission is to identify, engage, and qualify prospective clients to fuel the sales pipeline for our portfolio of services. You will work closely with marketing, inside sales, field sales, and scientific subject matter experts to generate high-quality leads, conduct initial outreach, and set the foundation for long-term client relationships. This role is ideal for a self-starter who thrives in a fast-paced environment, has strong communication skills, and is passionate about helping customers advance their scientific goals. ESSENTIAL DUTIES AND RESPONSIBILITIES: * Proactively source and qualify new business opportunities through a combination of outbound prospecting (calls, emails, LinkedIn, other data sources) and inbound lead follow-up. * Conduct discovery conversations with prospective clients to understand their research needs, qualify, and determine solution fit. * Collaborate with marketing to follow up on campaigns, webinars, tradeshows, and digital leads. * Accurately log and maintain all lead and prospect activity in Salesforce CRM. * Book qualified introductory meetings for Client Services, SMEs in appropriate Service Lines. * Maintain a consistent daily cadence of outreach activity, balancing volume and quality. * Research target accounts and industries to develop tailored messaging and outreach strategies. * Partner with sales leadership and scientific experts to refine messaging and targeting approaches. * Meet and exceed monthly KPIs for lead generation, qualification rates, and pipeline contribution. * Stay informed about Charles River services, therapeutic areas, and drug discovery and development trends to engage prospects credibly. Other Duties: * Build internal scientific and commercial relationships including knowledge of service lines and capabilities. * Partner with Commercial & Operational leadership to understand areas of need and gaps in pipeline inquiry volume to prioritize areas of prospecting focus. * Collaborate and communicate across sites, divisions, and functional teams to deliver on client expectations and ensure comprehensive solutions are proposed when needed. * Required to initiate Confidentiality Disclosure Agreements (CDA) where needed and MSA agreements when required. * Perform all other related duties as assigned. **Job Qualifications** * Education: Bachelor's degree (B.A./B.S.) or equivalent in business, marketing, or science related discipline. * Experience: 3-5 years sales, sales development representative, inside sales, or related experience. Experience in a contract research and/or pharmaceutical setting with knowledge of drug discovery a plus however not required. * An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above. * Capable of working with a minimum of supervision remotely, able to handle multiple tasks, and effectively prioritize based on departmental goals. Strong communication and interpersonal skills. * Organizational skills and attention to detail required. * Proficient in word processing, spreadsheet, and database software including Salesforce, LinkedIn Navigator, ZoomInfo, Crunchbase. Ability to work effectively and efficiently to meet deadlines. Understanding of business/sales process required. **Compensation Data** The pay range for this position is $33.00/hr. - $36.00/hr. + commission. Please note that salaries vary within the range based on factors including, but not limited to, experience, skills, education, certifications, and location. **About Corporate Functions** The Corporate Functions provide operational support across Charles River in areas such as Human Resources, Finance, IT, Legal, Sales, Quality Assurance, Marketing, and Corporate Development. They partner with their colleagues across the company to develop and drive strategies and to set global standards. The functions are essential to providing a bridge between strategic vision and operational readiness, to ensure ongoing functional innovation and capability improvement. **About Charles River** Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients' clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market. With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client's unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. At Charles River, we are passionate about our role in improving the quality of people's lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly worked on 80% of the drugs approved by the U.S. Food and Drug Administration (FDA) in the past five years. We're committed to providing benefits that elevate your quality of life. Based on your position these may include: bonus/incentives based on performance, 401K, paid time off, stock purchase program, Health and wellness coverage, employee and family wellbeing support programs, and work life balance flexibility. **Equal Employment Opportunity** Charles River is an equal opportunity employer and is committed to providing equal employment opportunities for all qualified applicants and employees without regard to race, color, sex, religion, national origin, ancestry, age, mental or physical disability, family status, pregnancy, military or veteran status, or any other characteristic protected by federal, state, or local laws. It is unlawful in some states (including Massachusetts) to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitment_**********. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications. For more information, please visit *************** 231536

The Executive Medical Director, Patient Safety/Head Medical Safety and Risk Management will oversee all safety and benefit-risk related activities of the GPS Physician (Disease-area Safety Heads, DST Chairs) and the Aggregate Report Risk Management (ARRM) Groups within the Vertex Global Patient Safety (GPS) Department. As a member of the GPS Senior Leadership Team, the role will contribute to ensuring consistency and compliance in the safety assessment, analysis and reporting for all designated product(s) throughout Vertex's world markets. Overseeing the GPS DASH/DST teams across therapeutic areas, the role will ensure consistent conduct and timely execution of Benefit-Risk activities by GPS DASH/DST teams, including pre-marketing risk assessment, planning for First-In-Human (FIH) studies, safety content of key Modules (SCS, CLO, Labelling) in regulatory authority submissions for approval, including planning, content and execution of Risk Management Plans (RMPs) and/or Risk Evaluation and Mitigation Strategies (REMS) for and post-marketing requirements. The role will work closely with leaders from cross-functional teams on the successful achievement of key strategic activities, initiatives and deliverables. Key Duties and Responsibilities: Provides leadership and oversight of DASH/Disease-area Safety Team(s) (DST) conduct, for all products across the Vertex Portfolio, including pre-FIH activities, key benefit-risk assessment, and providing strategy for DSTs to meet goals and objectives. Coordinates and oversees the consistent and timely review of safety data for identification of new safety signals, in accordance with Vertex signal detection practices. Collaborates with Clinical Leaders to develop and implement appropriate Risk Management procedures/plans for each product, both pre-approval and post-approval, as needed. Collaborates with NDA teams assessment, strategy and execution of key Regulatory Authority documents in support of submissions, specifically leading safety content of key Modules (SCS, CLO, Labelling) and development of any Risk Evaluation and Mitigation Strategy (REMS), Risk Management Plan (RMP) or equivalent documents. Collaborates with GPS Epidemiology with regards to development, implementation and reporting of pharmacoepidemiology studies, as needed. Reviews and/or assists in preparation of Developmental and/or Post-Marketing Periodic Safety Updates (DSURs, PSURs/PBRERs), IND packages, as well as NDA and INDs. Provides review and safety-specific input for labeling documents, including IB, CCDS, USPI, SmPC and other local labels, as applicable. Collaborates with Regulatory Affairs to develop responses to any safety related regulatory agency inquiries. Provides and oversees medical review of aggregate and/or individual post-marketing and clinical trial adverse event reports, in accordance with GPS review practices. Oversees medical evaluation of other relevant non-AE/SAE related safety information, such as from Toxicology, Non-Clinical studies and Product Quality sources. Reviews and provides oversight for medical content for key study-related documents, e.g., Protocols, Statistical Analysis Plan, IB, ICF and IDMC Charter. Reviews and provides oversight in the analysis of safety data from on-going and completed clinical trials and representation in Clinical Study Reports. Reviews and provides oversight of safety sections of clinical study reports. Provides a contributory role in Partner /Affiliate agreements and interactions, as needed. Serves as Subject Matter Expert in departmental development activities including SOP and Work Instructions development. Leads Medical staff and liaise with Operations leads regarding optimal practice regarding collection, evaluation and processing of adverse experience reports, from a medical perspective. Leads and guides direct reports, regarding the scope of DASH/DST Chair Physician responsibilities, and the provision of sound medical input for all pre-marketing and post-marketing activities. Facilitates the growth and development of staff and direct reports. Knowledge and Skills: Extensive knowledge of GCP, ICH and Global regulations. In-depth and comprehensive knowledge of General Medicine. Strong leadership skills with the ability to communicate effectively in a matrix environment. Experience in the critical evaluation and interpretation of data, with ability to synthesize into clear, coherent messaging. Extensive knowledge of Benefit-Risk strategies and decision-making. Ability to multi-task, adeptly handling multiple demands. Education and Experience: MD, DO or equivalent ex-US medical degree 12+ years of work experience with experience in Pharmacovigilance and 7 years of supervisory/management experience, or the equivalent combination of education and experience #LI-AR1 Pay Range: $312,000 - $468,000 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we'll help you build a career that you can feel passionate about. **Job Summary** We are seeking an experienced individual for our Corporate Counsel - Labor & Employment position within our Legal Department. Working with other members of the legal labor and employment team, provide analysis and counsel to management and HR on global labor and employment issues including recruitment and hiring, discipline, reorganizations, training, company policies, employee handbooks, compensation and benefits issues, etc. Draft, negotiate and review documents relating to executive employment, as well as general HR-related contracts including separation agreements. Develop and recommend company policy and position on worldwide labor and employment issues to ensure company compliance with local, state and federal regulations related to employment (Affirmative Action, ADA, FLSA, FMLA, EEOC, MCAD, NLRB, USERRA etc.) and related regulations in other jurisdictions where employees are situated. Handle employment -related litigation, mediations, hearings (EEOC, etc.), and arbitrations. Anticipate and guard against labor and employment legal risks facing the company. Provide general legal support, when appropriate. **Position is remote and will require occasional domestic and international travel. Essential Duties and Responsibilities + Provide analysis and counsel on labor and employment issues globally. Key areas include recruitment and hiring, discipline, reorganizations, training, company policies, employee handbooks, compensation and benefits issues. + Assist with legal compliance initiatives (policies, trainings, processes, etc.) related to employment and labor areas for the global workforce, as well as in other areas requested from time-to-time, and otherwise provide support generally to members of the legal compliance function. + Draft, negotiate and review documents related to senior executive employment and compensation, including benefits plan documents (including ERISA, COBRA and 409A issues), change-in-control agreements, and employment offer letters. + Draft, negotiate and review both routine and complex HR-related contracts including separation agreements. + Prepare and conduct training for HR and business partners on labor and employment issues and best practices. + Provide counsel on employment disputes, including EEOC, NLRB, MCAD and other discrimination complaints. + Recommend, advise and enforce company policy and position on worldwide labor and employment issues to ensure company compliance with local, state and federal regulations related to employment (Affirmative Action, ADA, FLSA, FMLA, EEOC, MCAD, USERRA etc.) and related regulations in other jurisdictions where employees are situated. + Manage outside counsel on employment litigation matters. + Review employment, labor and benefit issues as part of our acquisitions and divestiture teams, and provide related advice, counsel and risk assessments during the evaluation process. + As requested, serve as Legal Department representative on acquisition integration processes. + As requested, serve as Legal Department representative on Policy Management Committee. + Provide legal counsel on issues arising from actual or anticipated employment-related lawsuits. + Assist in the development and recommendation of company policy and position on employment-related legal issues. + Monitor and analyze changes to employment-related laws and regulations to ensure continued company compliance. Proactively advise management on changes which may affect the business and recommend actionable guidance. + Establish a strong partnership with HR and business teams, providing practical and sound labor and employment advice. + Provide backup legal support for general corporate legal issues as required. + Perform all other related duties as assigned. (Note: Position may be requested in the future to also serve as principal counsel to one or more businesses or functions, including coordinating the delivery of legal services to the businesses/functions and collaborating and establishing strong relationships with their respective leadership teams.) **Job Qualifications** + Education: Bachelor's degree (B.A./B.S.) and Juris Doctor or equivalent from an accredited law school. + Experience: Five or more years of related experience, preferably in a combination of a law firm and corporate setting. + An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above. + Certification/Licensure: Current license in any US State Bar as an attorney qualified to practice law. + Other: Knowledge of labor/employment-related statutes and regulations. Strong interpersonal and communication skills. Compensation Data The pay range for this position is $180K - $210K USD annually. Please note that salaries vary within the range based on factors including, but not limited to, experience, skills, education, certifications, and location. **About Corporate Functions** The Corporate Functions provide operational support across Charles River in areas such as Human Resources, Finance, IT, Legal, Sales, Quality Assurance, Marketing, and Corporate Development. They partner with their colleagues across the company to develop and drive strategies and to set global standards. The functions are essential to providing a bridge between strategic vision and operational readiness, to ensure ongoing functional innovation and capability improvement. **About Charles River** Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients' clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market. With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client's unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. At Charles River, we are passionate about our role in improving the quality of people's lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly worked on 80% of the drugs approved by the U.S. Food and Drug Administration (FDA) in the past five years. We're committed to providing benefits that elevate your quality of life. Based on your position these may include: bonus/incentives based on performance, 401K, paid time off, stock purchase program, Health and wellness coverage, employee and family wellbeing support programs, and work life balance flexibility. **Equal Employment Opportunity** Charles River is an equal opportunity employer and is committed to providing equal employment opportunities for all qualified applicants and employees without regard to race, color, sex, religion, national origin, ancestry, age, mental or physical disability, family status, pregnancy, military or veteran status, or any other characteristic protected by federal, state, or local laws. It is unlawful in some states (including Massachusetts) to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitment_**********. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications. For more information, please visit *************** 231226

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge. Job Description Clinical Site Startup & Engagement's vision is to expand Takeda's operational capabilities and drive effective, proactive global clinical-trial planning and management. Through strategic advancements in clinical research and development, CSSE aims to introduce greater efficiencies that make Takeda a preferred partner for sites, fostering a collaborative environment and enabling a more efficient delivery of Takeda's pipeline. CSSE's mission is to work collaboratively, with both internal and external partners, to deliver best-in-class trial execution, identify innovative ideas and employ business process excellence to compliment strategic growth and positively impact cycle time, quality, compliance, and resource utilization. Role Overview: The interns will support the current and future fiscal year business efforts for the Clinical Site Startup & Engagement team in the following departments: Feasibility and Trial Equity Study Start-Up Patient Recruitment & Retention Interns will have the opportunity to partner with other business units (Clinical Operations, Regulatory, Legal, Field Medical, R&D Health Equity, etc.) that regularly collaborate in the support of business goals. Interns will develop their knowledge of the R&D process by shadowing CSSE colleagues. This will include attending trial team meetings and strategy sessions, as well as meeting with vendors and our CRO partners. Interns will be expected to present a conclusionary presentation highlighting their experience and sharing learnings. How You Will Contribute: Feasibility Support the identification of the competitive landscape for a given trial/indication Study Start-Up Review the documents Study Start-Up is responsible for tracking Support the tracking of reportable metrics Patient Recruitment & Retention Support the Patient Recruitment and Retention strategy development with a focus on identifying successful methods for effective clinical trial messaging and tactics that will resonate with a broad segment of the population. Trial Equity Support the development of a global diversity strategy Support includes but not limited to data aggregation related to the demographics of disease, support trial teams with researching local community-based partnerships and assisting in maintaining the D&I in Clinical Trials resource database (store on SharePoint). Develop their knowledge of the R&D process by shadowing CSSE colleagues in their support of at least 1 trial. Collect external communications related to D&I in Clinical Trials to help build their personal acumen. Internship Development Opportunities: The intern(s) will develop strong analytical, problem-solving, and oral/written communication skills through working with other teams, effectively managing projects, and delivering presentations The intern(s) will develop an analytical approach of compiling data to help drive discussions and decisions The intern(s) will develop an ability to complete scientific research leveraging both internal & external resources The intern(s) will develop a basic ability to summarize scientific research and provide high-level reporting The intern(s) will develop a basic ability to complete data analysis, drawing conclusions/interpreting data Job Requirements: This position will be fully remote Must be pursuing a bachelor's degree in marketing, natural & physical sciences (biology, chemistry, physics, etc.), biostatistics, mathematics, bioengineering, biomedical engineering, gender studies, ethnic cultural studies, world culture, health education, nursing, medical sciences, pre-pharmaceutical studies or pharmaceutical science Must have mid-level proficiency with Microsoft applications (Excel, Word, and PowerPoint), compiling statistics, database management, quantitative & qualitative research, basic project planning, research, and basic technical writing Internship Eligibility Must be authorized to work in the U.S. on a permanent basis without requiring sponsorship Must be currently enrolled in a degree program graduating December 2026 or later The internship program is 10-12 weeks depending on the two start dates (May 26th-August 14th or June 15th- August 21st) The intern must be able to commit to one of these time frames Able to work full time 40 hours a week during internship dates Takeda does not provide a housing stipend or relocation support for the U.S Summer Internship Program Program Highlights: Hands-on experience with real projects and responsibilities Dedicated mentorship program pairing interns with experienced professionals Networking opportunities with industry professionals and fellow interns Internship events focused on professional and skills development Exposure to multiple business areas or departments within a Pharmaceutical Organization Applications will be accepted between November 7th - January 2nd Takeda Compensation and Benefits Summary We understand compensation may be an important factor as you consider an internship opportunity. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. For Location: Massachusetts - Virtual U.S. Hourly Wage Range: $21.00 - $46.00 The estimated hourly range reflects an anticipated range for this position. The actual hourly wage offered will depend on the candidate's school year/level to be entered following completion of internship. The actual hourly wage offered will be in accordance with state or local minimum wage requirements for the job location. U.S. internship benefits vary by location and may include: Paid sick time Civic Duty paid time off Participation at company volunteer events Participation at company sponsored special events Access to on-site fitness center (where available) Commuter Benefit: To offset your work-commute expenses, Takeda provides U.S. employees with a fixed monthly subsidy to be used for either public transportation (transit) or parking. EEO Statement Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law. LocationsMassachusetts - VirtualWorker TypeEmployeeWorker Sub-TypePaid Intern (Fixed Term) (Trainee) Time TypeFull time Job Exempt NoIt is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

**Job Title:** Director, US Regulatory Affairs - Advertising and Promotion (Hybrid) **About the Job** Are you ready to shape the future of medicine? The race is on to speed up drug discovery and development to find answers for patients and their families. Your skills could be critical in helping our teams accelerate progress. As the Director, US Regulatory Affairs - Advertising and Promotion, you'll partner with other key functional teams to ensure materials are consistent with US regulations, company policy and industry guidelines. You'll be asked to solve problems creatively and strategically, and introduce innovative concepts to more effectively manage ad/promo projects. This is a subject matter expert role wiht no direct reports, though there will be mentoring, training and team leadership opportunities. We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people's lives. We're also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started? **Main Responsibilities:** + Understanding of the U.S. pharmaceutical marketplace and familiarity with medical terminology. + Understands issues, problems, and opportunities by comparing data from different sources to draw conclusions and then can choose a course of action or develop the appropriate solution. + Regularly demonstrates the ability to participate in a more strategic capacity in the functional area and day-to-day decision-making process. + Makes decisions, provides direction and oversight for the day-to-day activities for assigned products, departmental activities, and direct reports. + In conjunction with the Sr. Director/Product Support Head, imparts senior regulatory guidance and advice during issues management activities; provides oversight and guidance for Rapid Response Teams, and functions as the therapeutic product expert. + Continually monitors the regulatory environment, interprets new regulations, guidance, and enforcement activities/trends and evaluates the impact on external environments and the business. + Develops and implements regulatory strategies for marketed products within their product area and mentor and develop others in executing strategy. + Establishes and develops key internal relationships with therapeutic product leaders to foster open communication and teamwork. + Assures alignment and consistency in policy application within and across therapeutic products; takes into account the totality of product-related and company activities. + Assists in ensuring product support relationships with FDA are established and maintained. + Provides input into the global organization for labeling strategies of marketed drugs. + Demonstrates significant autonomy in carrying out assigned duties and responsibilities. **About You** + Earned Bachelor's degree (required) from an accredited four-year college or university in a Life Sciences or other relevant discipline + 8+ years of experience within pharmaceutical or medical device Regulatory Affairs, with 5+ years specifically within advertising & promotion functions + Leadership, mentoring and/or training experience within regulatory or ad/promo is highly preferred + Extensive knowledge and understanding of complex medical and scientific subject matter, including statistical data. + Can build networks to obtain cooperation without relying on authority, including participating in cross-functional groups (medical, legal, regulatory, etc.) to lead toward decisions. + Ability to generate innovative solutions in work situations, trying different and novel ways to deal with work problems and opportunities. + Shows ability to use appropriate interpersonal styles and techniques and can modify behavior to gain acceptance of ideas or plans. + Able to establish priorities and timelines to effectively self-manage workload. Is able to multitask exceptionally well. + Deals with people in an honest and forthright manner representing information and data accurately. **Why Choose Us** + Bring the miracles of science to life alongside a supportive, future-focused team. + Discover endless opportunities to grow your talent and drive your career, whether it's through a promotion or lateral move, at home or internationally. + Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact. + Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks' gender-neutral parental leave. Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. \#GD-SA \#LI-SA \#LI-Onsite \#vhd **Pursue** **_progress_** **, discover** **_extraordinary_** Better is out there. Better medications, better outcomes, better science. But progress doesn't happen without people - people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let's be those people. At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity. Watch our ALL IN video (************************************************** and check out our Diversity Equity and Inclusion actions at sanofi.com (************************************************************************ ! _US and Puerto Rico Residents Only_ Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally inclusive and diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; natural or protective hairstyles; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. _North America Applicants Only_ The salary range for this position is: $172,500.00 - $249,166.66 All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs. Additional benefits information can be found through the LINK (********************************************************************************************************* . Global Terms & Conditions and Data Privacy Statement (*************************************************************** Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions. With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe. Discover more about us visiting ************** or via our movie We are Sanofi (***************************** As an organization, we change the practice of medicine; reinvent the way we work; and enable people to be their best versions in career and life. We are constantly moving and growing, making sure our people grow with us. Our working environment helps us build a dynamic and inclusive workplace operating on trust and respect and allows employees to live the life they want to live. All in for Diversity, Equity and Inclusion at Sanofi - YouTube (************************************************

Through internal audits the Internal Audit Manager will identify risk areas, evaluate business process controls and complete test plans on operational audits. Additionally, this role will provide recommendations to improve the effectiveness and efficiency of operations and business systems. This role will also participate in ensuring that the yearly internal control review is brought to fruition by interacting with SOX testers, other stakeholders, and subject matter experts on special projects and the development and execution of departmental goals. Key Duties and Responsibilities: Plans and performs financial, operational and, as applicable, IT audits; reviews related records for compliance with established and relevant reporting policies and procedures and is responsible for the end-to-end execution projects. Applies financial and quantitative analyses and risk assessment procedures, documents findings/work papers in support of departmental goals and objectives Maintains and applies an understanding of generally accepted accounting principles/standards and/or general IT frameworks Identifies and effectively communicates (both verbally and/or in writing) audit results, control weaknesses, accounting/reporting/application deficiencies, process or company risk, business productivity and efficiency opportunities, departmental vision, and any other relevant matters to management or other applicable parties Reviews, appraises and tests the internal controls surrounding business processes to assess compliance with the Sarbanes-Oxley Act Collaborates constructively and respectfully with fellow audit team members and business stakeholders including with multicultural teams and in global locations Maintains communication with the Engagement Director, responds to feedback and adjusts approach as the situation warrants Contributes in management meetings, presents findings, conclusions and recommended actions to business management Knowledge and Skills: Experience within Life Sciences or related sector Excellent organizational and project management skills Excellent written and verbal communication skills Detail oriented, able to multitask and meet deadlines Able to work under general supervision and work collaboratively with diverse teams Expanded knowledge of audit methodology, risk assessment and internal control concepts Ability to analyze process workflows and identify gaps and bottleneck Ability to perform data analytics, SOC1 reviews and understand ITGCs Obtain and provide training to the audit staff to support all aspects of Internal Audit activities to ensure that approved audit objectives are met Ability to operate effectively independently and in a team-oriented, multiple location environment CPA, CIA or CISA certifications or equivalent Education and Experience: Bachelor's degree in accounting/finance/information systems or related field Typically requires 5+ years of auditing experience (Big 4 strongly preferred) or the equivalent combination of education and experience. #LI-DB1 #HYBRID Pay Range: $111,700 - $167,600 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Vertex is seeking a talented and motivated individual to join its Global Health Economics & Outcomes Research (HEOR) group based in Boston's Seaport District. The Health Economics & Outcomes Research Associate Director will participate in the shaping and execution of HEOR strategies that optimize the value proposition for Vertex's Cystic Fibrosis and early pipeline assets through each stage of development, including launch and post-launch phases. This position reports to the Senior Director HEOR, CF and Early Pipeline. Key Duties and Responsibilities: Leads execution of complex HEOR evidence generation studies, including: prospective and retrospective observational studies, systematic literature reviews, cost-effective analyses and budget impact models, Indirect Treatment Comparisons, COA strategy, PRO measure development and validation, as needed, to support the asset value Effectively leads external research partners to ensure robust scientific methods are applied to study design and execution and in compliance with all local regulations; is accountable for study design, data analysis and the quality of the evidence produced. Excellent project management is a pre-requisite to ensure studies delivered on time and within budget. Collaborates with the medical communications teams on publication strategy and ensure that dissemination of HEOR evidence is timely and has maximum impact Partners and works closely with Global Pricing and Market Access to support development of product value proposition/value messaging and co-lead development of robust Global launch deliverables (e.g., global value dossier) Knowledge and Skills: Strong track record of publication in peer-reviewed journals Strong background in clinical outcome assessment (COA) measurement strategy; experience in PRO development/validation and qualitative research methodology Technical expertise in HEOR; able to formulate and lead creative research projects and ensure conduct is technically and scientifically rigorous and reflects best HEOR practices Strong verbal and written communications skills, including presentation skills to communicate difficult concepts and persuade others; comfortable communicating complex concepts and adapting presentation style to a variety of audiences Ability to apply knowledge of US healthcare system, global health technology appraisal requirements, and clinical development, to identify evidence gaps and formulate evidence generation strategies Understanding of the legal and regulatory environment of the pharmaceutical industry, with spotless history of compliance and ethical workplace conduct Education and Experience: Advanced degree (PhD, MD, Master's degree, MPH, or PharmD) in a relevant discipline. Typically requires 8 years of experience, with substantial background in HEOR, or the equivalent combination of education and experience Pay Range: $172,000 - $258,000 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Clinical Outcomes Pharmacist - Remote Drive impact from anywhere-optimize therapy results through virtual care. Key Responsibilities: Conduct comprehensive virtual medication therapy reviews (MTMs). Monitor therapy outcomes, document interventions, and report improvements. Collaborate with remote care teams to adjust treatment plans. Analyze patient data to identify trends and recommend optimizations. Provide virtual education to patients on medication adherence and safety. Qualifications: PharmD with active, unrestricted license (multi-state a plus). Strong clinical background with remote/telehealth experience preferred. Analytical skills and comfort with digital health tools. Why Join Us? 100% remote flexibility Technology and clinical support Performance-based bonuses

The Associate Director, Medical Writing Science manages the overall operations of a team or major project and implements this through effective leadership. This role provides guidance and leadership for document development for regulatory filings and coordinates the clinical sections of more complex regulatory submissions, including organization, content, and resource requirements. This role applies advanced technical expertise and develops solutions to complex problems, fosters interdisciplinary understanding, and integrates Medical Writing Science department activities with those of other departments. This is a hybrid role which allows for 2 days per week remote work and 3 days per week in the Boston Fan Pier office. We offer a full relocation package. Key Duties and Responsibilities: Independently authors routine and complex clinical and regulatory documents Provides strategic input into program-level plans Deep insight into how different functions contribute to the successes of the team Aligns, coordinates, and builds consistent information and messages across clinical program(s) Provides leadership related to the activities of Medical Writing Science and manages a team Participates in developing and implementing goals and initiatives for Medical Writing Science Facilitates implementation of new technologies and initiatives related to the preparation of clinical documents Proactively anticipates risks, solves complex problems, and seeks out and implements process improvements Knowledge and Skills: Demonstrated aptitude for planning, managing, and optimizing department resources (e.g., staff, technology) to maximize and streamline the advancement of company goals and objectives Record of leadership, independence, and ability to solve non-routine, complex problems involving a broad range of issues Proven track record of anticipating potential problems and preparing contingency plans as needed Understanding of scientific disciplines beyond own specialty area Experience managing direct reports and guiding staff development Experience with marketing authorization application regulatory submissions Education and Experience: Bachelor's degree in relevant discipline Ph.D. (or equivalent degree) Typically requires 8 years of work experience and 2 years of supervisory/management experience, or the equivalent combination of education and experience #LI-AR1 #LI-Hybrid Pay Range: $157,600 - $236,400 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Remote-Eligible Flex Eligibility Status: In this Remote-Eligible role, you can choose to be designated as: 1. Remote: work remotely five days per week and come into the office on occasion - you're always welcome on-site; or select 2. Hybrid: work remotely up to two days per week; or select 3. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. #LI-Remote Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

About The Role As a Product Specialist, you will be a crucial technical resource supporting our sales team in acquiring new customers and partners. You will leverage your scientific background and understanding of the pharmaceutical and biotechnology industries, particularly in Chemistry, Manufacturing, and Controls (CMC), to provide technical expertise throughout the sales cycle. This includes delivering compelling product demonstrations, answering complex technical questions, developing comprehensive responses to RFPs, and designing tailored solution architectures to meet prospect needs. You will bridge our technical capabilities and our customers' scientific and operational requirements, ensuring they understand the value and impact of our platform. This role requires a detail-oriented individual with strong communication skills and a passion for helping customers solve their challenges. What You'll Own Pre-Sales Technical Support: Serve as the primary technical point of contact for the sales team, providing expert guidance and support throughout the sales process. Conduct engaging and informative product demonstrations tailored to specific prospect needs and workflows within CMC and related areas. Effectively address technical questions and concerns from prospects, clearly articulating the capabilities and benefits of our platform. Develop detailed and persuasive responses to Requests for Proposals (RFPs) and Requests for Information (RFIs), highlighting our technical strengths and differentiation. Collaborate with Account Executives to understand prospect requirements and design optimal solution architectures that align with their scientific workflows. Solution Expertise: Maintain a deep understanding of our platform's features, functionality, and technical architecture. Develop and maintain expertise in the scientific workflows within pharmaceutical and biotechnology manufacturing, particularly CMC and related software solutions (e.g., LIMS, ELN, MES, RIM). Stay current on industry trends, emerging technologies, and the competitive landscape within the pharma/biotech SaaS space. Articulate the value proposition of our platform in the context of customer-specific scientific and business challenges. Content and Tool Development: Contribute to the development of technical sales collateral, including demo scripts, presentations, FAQs, and technical documentation. Identify opportunities to create reusable solutions, templates, and best practices for common customer use cases. Provide feedback to the Product and Engineering teams based on customer interactions and market insights. Customer Engagement and Relationship Building: Build strong relationships with prospective customers, establishing credibility and trust through your technical expertise. Understand customer scientific processes, data management practices, and IT infrastructure. Collaborate with internal teams (Sales, Product, Customer Success) to ensure a seamless customer experience. Travel and Industry Participation: Travel to customer sites as needed for meetings, demonstrations, and technical workshops (Up to 30% of time). Attend industry conferences and events to stay informed about market trends and network with potential customers (20%). Requirements What You Need To Succeed Education and Experience: Bachelor's degree in a scientific discipline, preferably Biology, Chemistry, or related field. 3+ years of professional experience in the pharmaceutical or biotechnology industry. Specific experience in pharmaceutical/biotech manufacturing, particularly within CMC (Chemistry, Manufacturing, and Controls), is highly desirable. (Bonus) Experience with common CMC scientific workflow tools such as LIMS, ELN, MES, and RIM systems. (Bonus) Experience in a digital strategy, technology, or software company. (Bonus) Experience in a sales or customer-facing role. Skills: Technical Proficiency: Understanding and articulating complex technical concepts related to software and scientific workflows. Scientific Acumen: Strong understanding of scientific principles and processes within the pharmaceutical and biotechnology industries. CMC Expertise: Solid understanding of CMC processes, regulatory requirements, and everyday challenges. Excellent Communication Skills: Exceptional written and verbal communication skills, with the ability to explain technical information to technical and non-technical audiences. Presentation Skills: Ability to deliver engaging and persuasive product demonstrations. Problem-Solving: Analytical and problem-solving skills to address customer technical challenges. Detail-Oriented: Strong attention to detail, particularly when responding to RFPs and designing solutions. Collaboration: Ability to work effectively with sales teams and other internal stakeholders. Customer Focus: A genuine desire to understand and meet customer needs. Personal Attributes: Enthusiastic and self-motivated. Adaptable and able to thrive in a fast-paced environment. Strong work ethic and a commitment to excellence. Passion for technology and its application in the life sciences. Benefits What You Will Love About Us Culture of teaching and learning. Competitive compensation package. Health Insurance - Good health promotes good work. We provide competitive health insurance benefits and flexible plans for you and your family members (applicable to U.S.-based employees only). Disability Insurance - For the unexpected situation where your ability to work and earn for you or your family gets disrupted, you can get access to short-term and long-term disability insurance (applicable to U.S.-based employees only). Mental Health Services - We provide access to mental health services via our employee platform (applicable to U.S.-based employees only). Family-Friendly PTO Policies - Unlimited vacation policy is reflective of our family-first culture and to encourage a healthy work-life balance. Hybrid Office Model - As a virtual company with teammates located around the world, you will have the option to work from home and/or to go into an office if you are near a QbDVision office location. Stipends for equipment, office supplies and personal development (conferences, skill training, etc.).

As a key leader within the Strategic Sourcing function, the individual will be tasked with managing and formulating strategies for Marketing categories to facilitate and enhance commercialization across various disease areas and regions. This role encompasses the oversight of the category life cycle, which includes the development and implementation of multi-year sourcing strategies, in addition to the ongoing management of strategic supplier relationships and performance evaluation. In partnership with Business Units and Finance, this position will be tasked with setting category objectives and will assume complete responsibility for their implementation. You will assist in the ongoing management of essential strategic suppliers to promote continuous improvement, address complex challenges, and uncover new opportunities that deliver outstanding value to Vertex and, ultimately, our patients. You embody a commitment to lifelong learning, demonstrating a strong sense of curiosity and adaptability, while consistently seeking to broaden your expertise beyond your immediate remit as part of your personal development. This position is highly visible throughout the organization and you are a leader who is comfortable, adept and effectively communicates with Senior Executive leaders. This position is based in our Boston, MA office, located in the Seaport area. This role requires a hybrid work schedule: 3 days in office & 2 days remote on a weekly basis. The role is global and will require some travel to all other facilities and locations (including London) to establish / maintain key business stakeholder relationships. Key Responsibilities: Strong business partnering acumen to develop trusting and influential relationships with stakeholders, understand business objectives and challenges, bring supplier and marketplace expertise, collaborate on multi-year strategic and operational plans, and drive business outcomes. Develop, implement, monitor and maintain category strategies in partnership with Business stakeholders for all related sub-categories, including continuous refreshment and improvement of category strategies to meet evolving business needs Own the Supplier Performance/Relationship Management process including supplier performance monitoring. Responsible for meeting preparation, pre-read documents, performance dashboards, capturing action items, and ensuring appropriate follow-up including Executive Business Reviews In collaboration with the Business, responsible for defining Key Performance Indicators (KPIs) and associated performance metrics and are integrated into contractual documents and captured on Dashboards to ensure supplier performance is meeting expectations and continuously improving Support the Business Owner with identification of all applicable risks as part of the Sourcing process, including coordination with Risk Subject Matter Experts to properly assess and develop mitigation plans, where necessary Manages complex negotiations on price and terms, that often include other internal stakeholders such as Business Partners and Legal. Able to independently create comprehensive negotiation planners that all internal parties are aligned with upfront Acts as mentor to support Sourcing colleagues, temporary workers, and/or college co-ops, as directed by their manager Required Education, Experience and Competencies: Bachelor's Degree and MBA required 10+ years of strategic sourcing experience including relevant Marketing Procurement experience Good understanding of the nuances associated with a regulated environment AI-ready mindset, passionate individual about AI opportunities and overall impact in Services area Embody a Can-Do- Mindset, thriving in ambiguity, while building bridges thanks to innovative solutions Strong analytical capabilities | Project management skills | Good communication and presentation skills, able to clearly articulate opinions in concise and persuasive manner Excellent communication and organizational skills. Comfortable interfacing and presenting to senior leadership in a concise, well-planned manner. Pay Range: $175,200 - $262,800 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Be a part of the legacy: Postdoctoral Research Fellow Program Our Research Laboratories' Postdoctoral Research Fellow Program aims to be a best-in-industry program for industrial postdoctoral researchers, designed to provide you with an academic focus in a commercial environment. With the resources, reach, and expertise of a large pharmaceutical company, postdoctoral researchers will be positioned to excel in an institution committed to breakthrough innovation in research and discovery. The Pharmacokinetics, Dynamics, Metabolism, and Bioanalytics (PDMB) function at research laboratories is seeking a highly motivated postdoctoral fellow with expertise in machine learning to help transform drug discovery and preclinical development. You will join an interdisciplinary team and collaborate closely with research partners across our global organization. You will invent, prototype, and apply advanced Machine Learning (ML) methods-particularly in generative modeling and related areas-to expand our capabilities in designing, prioritizing, and characterizing novel therapeutic candidates. Primary Responsibilities Conduct original research to develop state-of-the-art AI/Machine learning methods for drug discovery (e.g., molecular generative models, multi-objective optimization, property prediction, active learning, document authoring, document generation, hybrid AI system, multi-agent system) Design and execute experiments, analyze results rigorously, and iterate rapidly on model architectures and training strategies Build robust, reproducible code and workflows; contribute to shared libraries and documentation Collaborate with chemists, biologists, Pharmacokinetics, Dynamics, Metabolism, and Bioanalytics (PDMB) scientists, and data/ML engineers to translate methods into impactful applications Communicate findings through internal presentations and peer-reviewed publications; present at conferences and workshops Education Minimum Requirements Ph.D. (or completion within six months) in Computer Science, Statistics, Physics, Applied Mathematics, Bioinformatics, Computational Biology, Chem/Informatics, Engineering, or a related field Required Experience and Skills Demonstrated research excellence and problem-solving ability; strong motivation to learn, innovate, and deliver Proficiency in core ML/statistics topics such as probability, statistical inference, optimization, discrete math/algorithms, and/or probabilistic modeling Strong programming skills in Python and experience with modern ML frameworks (e.g., PyTorch, TensorFlow) Track record of publications and/or presentations in ML, computational chemistry/biology, or related fields Excellent collaboration and communication skills; proven ability to work in cross-functional teams Preferred Experience and Skills (nice to have) Experience with molecular representations (e.g., SMILES, graphs), generative models (e.g., diffusion models, VAEs, flow models), and sequence/structure models (e.g., transformers, GNNs, protein or RNA models) Familiarity with cheminformatics/biophysics toolkits (e.g., RDKit), docking or molecular simulation, ADMET modeling, or DMPK-relevant endpoints Practical experience with experimental design, active learning, uncertainty quantification, or multi-objective optimization Software engineering best practices (Git, testing, containers), and experience working with large datasets and cloud/GPU environment postdoctoralopportunities Required Skills: Accountability, ADME, Clinical Study Management, Dosage Forms, Drug Metabolism, Ethical Compliance, Innovation, Machine Learning (ML), Modeling Simulations, Personal Initiative, Pharmaceutical Analysis, Pharmacodynamics, Pharmacognosy, Pharmacokinetic Modeling, Pharmacokinetics, Protocol Development, Regulatory Submissions, Scientific Writing Preferred Skills: Current Employees apply HERE Current Contingent Workers apply HERE US and Puerto Rico Residents Only: Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process. As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit: EEOC Know Your Rights EEOC GINA Supplement We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively. Learn more about your rights, including under California, Colorado and other US State Acts U.S. Hybrid Work Model Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”. The salary range for this role is $70,500.00 - $110,900.00 This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee's position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs. The successful candidate will be eligible for annual bonus and long-term incentive, if applicable. We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at ******************************************************* You can apply for this role through **************************** (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting. San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance Search Firm Representatives Please Read Carefully Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. Employee Status: Regular Relocation: Domestic VISA Sponsorship: Yes Travel Requirements: 10% Flexible Work Arrangements: Not Applicable Shift: Not Indicated Valid Driving License: No Hazardous Material(s): n/a Job Posting End Date: 01/17/2026 *A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Role Overview & Key Functions: If you want to do something that matters, this work matters. Patients drive our passion to pioneer novel cancer therapies. That's why we've built an environment centered around support, flexibility, and a shared mission. Creating and delivering medicine for cancer can only be done through focus, dedication, and heart. We hire exceptional people and trust each other to work in whatever way lets us, be us - whether that's onsite, from home, or anywhere in between. Our summer intern program, which will run from May 25th - Aug 7th, allows students to gain real world work experience in a high energy, collaborative work culture. Role Overview & Key functions: We are seeking a motivated and detail-oriented Analytical Data Analyst Summer Intern to be part of our Analytical team. This internship offers hands-on experience in analytical data analysis, trending, and generating reports/dashboards to support business decision-making. This experience will enhance the Intern's career prospects in Analytical and related fields. * Transfer data between Smartsheet and excel worksheets/workbooks. Ensuring data integrity and correct formatting in the new destination file. * Develop complex spreadsheets including creating formulas, functions, PivotTables, Power Query, and data visualization tools to generate reports/dashboards for reporting metrics to be used for annual Quality Management Review (QMR) of XPOVIO products. * Improve filtering techniques for data queries. * Participate and collaborate in cross-functional meetings with Quality and Pharmaceutical Sciences to understand data requirements and deliver analytical support. * Perform administrative tasks related to documentation to standardize formats, ensuring version control and gap assessments for missing values or duplicates as needed. Candidate Profile & Qualifications * Enrolled in a full-time pharmaceutical science, or statistical degree program * Proficiency with Microsoft Office including Word, Excel, PowerPoint, and Teams * Proficiency with PowerBI, JMP or excel statistical add-on packages a plus * Strong organization skills with the ability to handle multiple projects simultaneously and effectively * Strong communication and time management skills capable of working independently and cross-functionally in a remote work environment * Familiar with data analytics and trending including excel for graphing and hyperlinking source documents * Analytical or quality control experience in small or large molecules or oral drug products a plus for exposure to different types of data * Interest in understanding FDA regulatory commitments in commercial programs * Familiar with cGMP, USP, FDA, and ICH requirements a plus * You have a strong interest in life sciences and are passionate about giving patients with cancer a chance to enjoy more of life's precious moments. * You feel a strong connection with our ICARE values (Innovation, Courage, Alignment & Accountability, Resilience, and Energy) * You demonstrate enthusiasm for learnin Candidate Profile & Requirements: * Must be able to complete the Karyopharm Internship Program 27 May - 08 Aug 2025 * Currently enrolled high school or college (bachelor's program) student * Student must be returning to school in the Fall Term. * Must have a minimum GPA of 3.0 * Must be highly organized and have the ability to work in independently and collaboratively as a team * Clear, concise verbal & written communication Pay for internships ranges from $22 to $30 per hour, depending on the student's academic level (e.g., Bachelor's, Master's) and year in school. Our Value Proposition: At Karyopharm, we live and demonstrate our ICARE values every day! Check out our Culture Video!

Vertex is seeking a hands-on, experienced consolidations leader with accounting systems and process expertise to join our Global Accounting organization. The Director, Accounting Systems & Consolidation will oversee the global close and consolidation process and drive accounting system and financial reporting excellence. In addition, the Director will closely partner with IT and other stakeholders to maintain and enhance our key accounting systems and applications such as HFM, Oracle EBS, and Blackline. This newly established role is ideal for a motivated leader who can effectively lead our small team of experienced professionals to align diverse stakeholders, foster collaboration, and deliver innovative solutions to advance our consolidation processes and accounting systems. Key Duties and Responsibilities: Drive process excellence for the monthly, quarterly, and yearly close and consolidation process, working closely with the appropriate stakeholders (global accounting, tax, treasury, finance and shared services) to ensure timely and accurate financial results Develop and execute strategy for various consolidation initiatives, such as intercompany automation, cloud-based applications, and RPA bots Partnering with Vertex's IT organization, maintain and support our key accounting systems and applications such as HFM, Oracle EBS, and Blackline, including change management for upgrades and enhancements Collaborate with global partners to formulate enhancement options to address specific functional issues/requirements Manage and oversee completeness and accuracy of system eliminations for intercompany balance sheet and income statement activity Develop and monitor metrics and key performance indicators that drive best practices Assist in the development of the overall Accounting Systems roadmap Effectively lead team of 4 experienced professionals; mentor, develop, retain and recruit high potential talent Knowledge and Skills: Expertise with complex integrated financial reporting systems, inclusive of HFM, Hyperion ESSbase and Oracle EBS Knowledge of financial consolidation, accounting for intercompany and foreign currency translations, eliminations, reporting for monthly and quarterly closes, general ledgers, hierarchies and data structures Direct management of governance and finance system compliance in accordance with company policies, standards and SOX requirements Strong systems mindset and understanding of accounting system workflows Applies knowledge and understanding of financial and US GAAP accounting principles to systems and business processes Ability to interact and partner with all levels of management to help drive collaborative business decisions Possesses interpersonal and organizational skills, high energy level and strong work ethic Able to anticipate change and respond to client priorities, demonstrating a “can do” attitude Excellent written and verbal communication skills including the ability to succinctly convey relevant information across multiple levels of the organization Finance process excellence or Six-Sigma experience a significant plus Education and Experience: Bachelor's degree in either Accounting, Finance, Information Technology, Business or a related field Typically requires 10+ years of experience in finance or accounting with a large, complex, multinational organization Big 4 experience and life science industry experience is preferred CPA or equivalent certifications are desirable A track record of success working in a team-based environment Pay Range: $173,600 - $260,300 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Povetacicept is a pipeline in a molecule with a potential to transform treatment outcomes for patients. The Director, Global Marketing of Povetacicept is accountable for key indications understanding the market landscape and Vertex's position within the market, actively contributing to defining the strategy and performance goals of the portfolio and tracking performance against those goals. Key Duties and Responsibilities: Develops the indication strategy for povetacicept for key indications, and oversees creation of brand strategies and lifecycle activities including launch planning and prioritization Oversees development and implementation of strategic and tactical plans working across functions for a unified indication plan Provides input into forecasting assumptions, both short term and long term Generates and consolidates key insights across HCPs and patient stakeholders (through market research, ad boards, etc.) Leads the development of strong partnerships with cross-functional team to support business goals including R&D and regional teams Knowledge and Skills: Experience defining the strategy for a brand or portfolio of products with multiple indications/pipeline in a product Ability to oversee generation of insights, and apply those insights to business problems/opportunities Analytical mindset, with demonstrated ability to develop strategy, make strategic recommendations, monitor performance, understand ROI and allocate resources Exceptional working knowledge of market forecasts and relationship of business drivers to revenue Experience in pharmaceutical marketing. In-market and /or global marketing experience required. Neurology experience preferred. Education and Experience: Bachelor's degree in marketing, business, or scientific degree Typically requires 12 years of experience or the equivalent combination of education and experience Pay Range: $195,200 - $292,800 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com