Biomedical scientist job description

You can have a positive impact on the scientific community!

The Leidos Life Sciences Operation of the Health Group is seeking a Biomedical Life Scientist who will provide scientific, meeting and technical support to the Congressionally Directed Medical Research Programs (CDMRP) in Frederick, Maryland. This is NOT a laboratory research position.

The CDMRP is a leading funder of research projects across a broad range of medical fields and military health. The Leidos Biomedical Life Scientist will work across a diverse variety of research programs in support of the CDMRP's goal to transform healthcare through innovative and impactful research.

+ Leidos Life promotes excellent work-life balance. You can make an impact and have time for your well-being.

+ This position is eligible for partial remote work and a flexible work schedule.

+ Leidos offers many opportunities for career development and advancement within the Life Sciences Group and beyond.

+ Be a part of a large, dynamic workforce with a broad range of scientific expertise

Responsibilities:

+ Planning and execution of a variety of scientific meetings

+ Recruitment of scientists, clinicians and consumer advocates to participate in scientific meetings

+ Development and tracking of schedules for tasks and deliverables

+ Providing scientific notetaking support by recording critical information from scientific meetings and writing comprehensive meeting reports

+ Drafting scientific materials, including research highlights, meeting summaries, and funding opportunities

+ Conducting analyses of funding portfolio data and research outcomes and assembling data to prepare tables, graphs, and slides

Successful candidates will possess:

+ Strong interpersonal, written, and oral communication skills

+ Strong scientific writing skills

+ Exceptional attention to detail

+ Excellent organizational and time management skills

+ The ability to work effectively in a team environment

+ Proficiency with Microsoft Word, Excel, and PowerPoint

+ Experience using IT data management systems

Additional Requirements:

+ This position requires a U.S. citizen in order to obtain a U.S. Department of Defense Public Trust security clearance.

+ Some local travel within the Washington DC/Baltimore area is required.

Required Education:

A Master's degree from an accredited college or university in biology, life sciences, or a related discipline, with 1-2 years related experience is desired.

Pay Range:Pay Range $60,450.00 - $93,000.00 - $125,550.00

The Leidos pay range for this job level is a general guideline onlyand not a guarantee of compensation or salary. Additional factors considered in extending an offer include (but are not limited to) responsibilities of the job, education, experience, knowledge, skills, and abilities, as well as internal equity, alignment with market data, applicable bargaining agreement (if any), or other law.

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REQNUMBER: R-00082471

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status. Leidos will consider qualified applicants with criminal histories for employment in accordance with relevant Laws. Leidos is an equal opportunity employer/disability/vet.

Generate was founded in 2018 by Flagship Pioneering and has received over $420 million in funding, providing the resources to rapidly scale the organization. The Company has offices in Cambridge, Somerville, and Andover with approximately 200 employees.

The Role:

Generate Biomedicines is seeking an experienced, creative, and motivated Scientist I/II to join our rapidly growing Platform Innovation team. This highly synergistic team works at the intersection of synthetic biology, microfluidics, microfabrication, micro-automation, organ-on-a-chip, and Machine Learning to establish truly novel biological and biochemical workflows that help enable high-throughput data generation throughout the company. The ideal candidate has a proven track record of developing platforms for advanced 3D cell culture systems including bioreactor systems and sensors that plays a central role in organ-on-a-chip devices. For this position, a strong background and hands-on experience building fluidic micropumps with controlled pressure and flow, integrated leak-free microfluidic system with air-bubble trapping system, sensors and actuators, and high-quality data acquisition and analysis are required. Additionally, experience with tissue culture, organoid models, immune functional assays, immunohistochemical staining are preferable, as the successful candidate will play an important role in integrating candidate bioreactor systems into bioprinted tissue constructs. On top of this, she/he will be responsible for onboarding new technologies, supporting cross-team high-throughput workflows including the development of novel translational models for immunogenicity risk assessment and toxicity assays. This is an opportunity to be part of a hugely diverse and interdisciplinary team that performs highly innovative technology development, in the premier scientific environment of a well-funded biotech startup.

Responsibilities include, but are not limited to:

• Design, assemble, and evaluate device platforms including bioreactors, flow sensors, microfluidic pumps for organ-on-a-chip and microfabricated systems. Oversee workflows, and, if necessary, perform effective design modifications.
• Assure candidate systems capabilities by performing quantitative validation assessments, be responsible for monitoring and modifications of the system
• Develop, qualify, and validate advanced in vitro cell culture models incorporating microphysiological systems, organoids, organ-on-a-chip approaches for drug screening and toxicity assessments
• Perform cell-based bioanalytical assays with standard readout techniques in combination with bioimaging technologies
• Independently design protocols, execute experiments, generate relevant data, apply advanced data analysis, and deliver findings with the highest possible scientific standard
• Participate in writing reports, electronic lab notebooks, publications, and patents

Qualifications:

• PhD in Biomedical Engineering, Bioengineering, Mechanical Engineering, or a related discipline or MSc with at least 3 years of relevant experience
• Solid knowledge of mechanical theories, principles, practices, proven hands-on experience on advanced tissue culture systems including lab-on-a-chip, 3D organoids, and microfluidic devices
• Strong knowledge of CAD/CAM, MATLAB, SolidWorks and PDM, data analytics tools
• Relevant theoretical and practical knowledge within the fields of cell biology, tissue engineering, microfabrication, microfluidics is highly desirable
• Outstanding laboratory technique: primary cell culture, cell-based bioanalytical assays including in vitro/ex vivo cytotoxicity assays, FACS, immunostaining and IHC, confocal microscopy
• Excellent communication and presentation skills to properly deliver the results and collaborate with diverse team members
• Self-motivated and scientifically driven with a desire to learn from and teach others, ability to work as a team in a multidisciplinary, dynamic, and result-oriented environment

Generate Biomedicines is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

COVID Safety:

Generate Biomedicines enforces a mandatory vaccination policy for COVID-19. All employees must be fully vaccinated and have received a booster. The purpose of this policy is to safeguard the health of our employees, their families, and the community at large from infectious disease that may be reduced by vaccinations. The company will make exceptions to this policy if required by applicable law and will consider requests for an exemption from this policy due to a medical reason, or because of a sincerely held religious belief, or any other exemptions that may be recognized by applicable.

Recrui tment & Staffing Agencies : Generate Biomedicines does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Generate Biomedicines or its employees is strictly prohibited unless contacted directly by Generate Biomedicines's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Generate Biomedicines, and will not owe any referral or other fees with respect thereto.

**Release the power of precise proteomics at Cedars-Sinai!**

Join us as a scientific leader in cutting-edge quantitative proteomics to commercialize assay workflows and biomarkers for the diagnosis and treatment of human disease, and preventive health. The newly formed Precision Biomarkers Laboratories (PBL) at Cedar-Sinai, is seeking a candidate with comprehensive experience in the development of novel, high-performance quantitative ELISA assays with access to three different automated platforms. Experience in cell-free protein synthesis is also highly desired.

This position requires an individual with outstanding technical skills and scientific experience as well as excellent communication and collaborative skills. The individual must be able to work in a fast-paced clinical and product development environment to translate insights using proteomics into biomarker hypotheses that can be verified in large cohort studies.

You will be highly motivated, with a proven record of scientific productivity, excellence in communication, collaboration, and enthusiasm to join a growing, dynamic group. Your motivation, innovation, and attention to detail will augment your ability to work collaboratively. This is a unique opportunity to join a dynamic ecosystem that leverages disruptive innovation from internal academic research labs and the clinical healthcare infrastructure. Please visit Home - CSPBL (cs-pbl.com) to learn more.

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**Department-Specific Responsibilities:**

+ Direct experience developing of state of the art proteomic workflows, developing technology and working independently.

+ Experience across the entire proteomic workflow from sample prep to data analysis.

+ In-depth understanding of various quantitation technologies and their clinical applications.

+ Strong theoretical understanding of protein biochemistry and practical knowledge of analytical validation.

+ Extensive experience in instrumentation, trouble shooting, QC, standardization for proteomics workflow and pipeline development.

+ Ability to conduct data analysis and interpret biological meaning.

+ Demonstrated scientific productivity and have excellent oral and written communication skills.

+ Ability to manage multiple projects and timelines.

+ Willingness to think outside of the box to drive the implementation of innovative proteomic workflows that align with the business unit objectives.

**Education:**

+ Bachelor's Degree in molecular biology, microbiology, biochemistry or related science/engineering field required. Master's or Doctorate degree is preferred.

**Experience and Skills:**

+ Eight (8) years experience in GMP/GLP or equivalent regulated facility.

+ BSc/MS/Ph.D. with >3 years of professional experience in ELISA proteomics especially in areas with direct application to human health.

+ Experience with immunoaffinity, molecular biology, and cell culture is desirable.

+ Previous industry experience is a plus.

+ Demonstration of subject matter expertise through study designs and superior technical customer service.

**Working Title:** Biomedical Scientist - Molecular Biology - Clinical Proteomics

**Department:** Precision Biomarker Labs

**Business Entity:** Academic / Research

**Job Category:** ,Biomanufacturing,Biomanufacturing

**Job Specialty:** Biomanufacturing

**Position Type:** Full-time

**Shift Length:** 8 hour shift

**Shift Type:** Day

Cedars-Sinai is an EEO employer. Cedars-Sinai does not unlawfully discriminate on the basis of the race, religion, color, national origin, citizenship, ancestry, physical or mental disability, legally protected medical condition (cancer-related or genetic characteristics or any genetic information), marital status, sex, gender, sexual orientation, gender identity, gender expression, pregnancy, age (40 or older), military and/or veteran status or any other basis protected by federal or state law.