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Research Fellow jobs at Boehringer Ingelheim - 449 jobs

  • Metallurgical R&D Scientist

    HTI 4.3company rating

    Augusta, GA jobs

    HTI is seeking a Metallurgical R&D Scientist for a brand-new facility in Augusta, GA. This is a great opportunity to work with a state-of-the-art facility and be an important contributor to the growing North American metals supply chain. What They Offer Full Medical, Dental, and Vision Benefits on Day 1 401(k) Match EAP, LTD, STD, and Life Insurance Competitive Vacation Package 12 Paid Holidays Relocation Assistance Available What You Need Bachelor's Degree in Chemical Engineering, Materials Science, Metallurgy, or a related field Minimum of 2 years of experience, ideally in R&D, materials analysis, or process engineering Recent graduates with relevant project or lab experience may be considered Strong understanding of non-ferrous metallurgy and metal extraction principles, especially copper metallurgy. Knowledge of pyrometallurgical, hydrometallurgical, and/or electrometallurgical processes Experience with: Material characterization and analysis Process troubleshooting and optimization Failure analysis and root cause investigation Familiarity with process simulation or thermodynamic modeling tools (FactSage, Thermo-Calc, HSC, etc.) is preferred but not required Experience preparing or interpreting process flow diagrams, phase diagrams, and thermodynamic calculations **Candidates must be eligible to work in the U.S. without sponsorship now AND in the FUTURE** What Your Role Will Look Like As the Metallurgical Research & Development Scientist, you will be integral to the development and enhancement of metallurgical processes, particularly in non-ferrous extractive metallurgy with a focus on copper. Collaborating with various departments, you will lead process improvement initiatives through simulation and modeling, contribute to R&D projects, and support the broader organization in achieving its production and efficiency goals. Key Responsibilities Collaborate closely with cross-functional teams, including Production, Supply Chain, and Maintenance, to develop and optimize metallurgical processes. Design and improve processes through simulation, focusing on enhancing production efficiency and effectiveness. Conduct research and development projects, such as developing new copper alloys and analyzing the impact of using different types of electronic waste. Utilize process simulation software to model and simulate metallurgical processes, implementing improvements to existing operations. Prepare detailed process flow diagrams and perform calculations related to mass balance, heat balance, and phase diagrams. Support other departments by providing expertise on chemical and material compositions and addressing process-related questions. Ensure compliance with environmental, health, and safety standards, contributing to the development of operating instructions and risk assessments. Participate in the ongoing development of R&D labs on-site, with a focus on future process improvements and innovations.
    $52k-74k yearly est. 2d ago
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  • Research Scientist, Molecular Dynamics

    Recursion 4.2company rating

    New York jobs

    Your work will change lives. Including your own. The Impact You'll Make Recursion is a leading TechBio company that is transforming drug discovery by using AI and automation to find new medicines. Its powerful platform combines different technologies to create one of the world's largest proprietary collections of biological and chemical data. By running millions of lab experiments each week and using one of the most powerful supercomputers in the world, Recursion brings together technology, biology, and chemistry to revolutionize medicine. We are looking for an experienced and motivated scientist to join our computational physics team, which is essential for designing molecules in our pipeline by supporting active drug discovery projects. This team also develops and implements cutting-edge methods to keep our platform at the forefront of computational sciences. In this role, you will: Lead the development and implementation of advanced computational physics methods into efficient and scalable workflows, to address challenging drug discovery problems and drive project success Collaborate with software engineers and drug designers in multidisciplinary teams to deliver scientific solutions to complex technical problems Keep up with the latest scientific developments, assess new technologies for their use in internal workflows, and devise plans for their implementation Communicate your work to both internal and external audiences to guide decisions and contribute to the scientific community The Team You'll Join You will become an essential member of the Computational Physics team, which supports several phases of drug discovery, from initial hypothesis to lead optimization. The team's goal is to build highly accurate and automated atomistic models and pipelines to obtain crucial molecular-level insights for advancing drug candidates. We employ physics-based and physics-informed models, such as molecular dynamics simulations, absolute and relative binding free energy methods, metadynamics, MM/PBSA, and quantum-mechanical calculations, to enable cost-effective and scalable structure-based drug discovery. We work closely with design teams and collaborate with partners like the AI experts at the Frontier Hub, making our highly accurate methods more accessible and scalable for all. The Experience You'll Need PhD in Chemistry, Physics, Computational Chemistry, Computational Physics, or a related subject area Excellent programming skills in Python for tool development Proven track record in the development of molecular simulation or computational chemistry tools Basic knowledge of drug discovery processes and the application of molecular simulations in this field Experience in deploying and orchestrating large-scale jobs using compute clusters or cloud-based infrastructures Working Location & Compensation: This is an office-based, hybrid role in our New York office. Employees are expected to work in the office at least 50% of the time. At Recursion, we believe that every employee should be compensated fairly. Based on the skill and level of experience required for this role, the estimated current annual base range for this role is $129,000 to $163,300. You will also be eligible for an annual bonus and equity compensation, as well as a comprehensive benefits package. #LI-EP1 The Values We Hope You Share: We act boldly with integrity. We are unconstrained in our thinking, take calculated risks, and push boundaries, but never at the expense of ethics, science, or trust. We care deeply and engage directly. Caring means holding a deep sense of responsibility and respect - showing up, speaking honestly, and taking action. We learn actively and adapt rapidly. Progress comes from doing. We experiment, test, and refine, embracing iteration over perfection. We move with urgency because patients are waiting. Speed isn't about rushing but about moving the needle every day. We take ownership and accountability. Through ownership and accountability, we enable trust and autonomy-leaders take accountability for decisive action, and teams own outcomes together. We are One Recursion. True cross-functional collaboration is about trust, clarity, humility, and impact. Through sharing, we can be greater than the sum of our individual capabilities. Our values underpin the employee experience at Recursion. They are the character and personality of the company demonstrated through how we communicate, support one another, spend our time, make decisions, and celebrate collectively. More About Recursion Recursion (NASDAQ: RXRX) is a clinical stage TechBio company leading the space by decoding biology to radically improve lives. Enabling its mission is the Recursion OS, a platform built across diverse technologies that continuously generate one of the world's largest proprietary biological and chemical datasets. Recursion leverages sophisticated machine-learning algorithms to distill from its dataset a collection of trillions of searchable relationships across biology and chemistry unconstrained by human bias. By commanding massive experimental scale - up to millions of wet lab experiments weekly - and massive computational scale - owning and operating one of the most powerful supercomputers in the world, Recursion is uniting technology, biology and chemistry to advance the future of medicine. Recursion is headquartered in Salt Lake City, where it is a founding member of BioHive, the Utah life sciences industry collective. Recursion also has offices in Toronto, Montréal, New York, London, Oxford area, and the San Francisco Bay area. Learn more at ****************** or connect on X (formerly Twitter) and LinkedIn. Recursion is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other characteristic protected under applicable federal, state, local, or provincial human rights legislation. Accommodations are available on request for candidates taking part in all aspects of the selection process. Recruitment & Staffing Agencies: Recursion Pharmaceuticals and its affiliate companies do not accept resumes from any source other than candidates. The submission of resumes by recruitment or staffing agencies to Recursion or its employees is strictly prohibited unless contacted directly by Recursion's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Recursion, and Recursion will not owe any referral or other fees. Our team will communicate directly with candidates who are not represented by an agent or intermediary unless otherwise agreed to prior to interviewing for the job.
    $129k-163.3k yearly Auto-Apply 18d ago
  • Research Scientist, Molecular Dynamics

    Recursion Pharmaceuticals 4.2company rating

    New York, NY jobs

    Your work will change lives. Including your own. The Impact You'll Make Recursion is a leading TechBio company that is transforming drug discovery by using AI and automation to find new medicines. Its powerful platform combines different technologies to create one of the world's largest proprietary collections of biological and chemical data. By running millions of lab experiments each week and using one of the most powerful supercomputers in the world, Recursion brings together technology, biology, and chemistry to revolutionize medicine. We are looking for an experienced and motivated scientist to join our computational physics team, which is essential for designing molecules in our pipeline by supporting active drug discovery projects. This team also develops and implements cutting-edge methods to keep our platform at the forefront of computational sciences. In this role, you will: * Lead the development and implementation of advanced computational physics methods into efficient and scalable workflows, to address challenging drug discovery problems and drive project success * Collaborate with software engineers and drug designers in multidisciplinary teams to deliver scientific solutions to complex technical problems * Keep up with the latest scientific developments, assess new technologies for their use in internal workflows, and devise plans for their implementation * Communicate your work to both internal and external audiences to guide decisions and contribute to the scientific community The Team You'll Join You will become an essential member of the Computational Physics team, which supports several phases of drug discovery, from initial hypothesis to lead optimization. The team's goal is to build highly accurate and automated atomistic models and pipelines to obtain crucial molecular-level insights for advancing drug candidates. We employ physics-based and physics-informed models, such as molecular dynamics simulations, absolute and relative binding free energy methods, metadynamics, MM/PBSA, and quantum-mechanical calculations, to enable cost-effective and scalable structure-based drug discovery. We work closely with design teams and collaborate with partners like the AI experts at the Frontier Hub, making our highly accurate methods more accessible and scalable for all. The Experience You'll Need * PhD in Chemistry, Physics, Computational Chemistry, Computational Physics, or a related subject area * Excellent programming skills in Python for tool development * Proven track record in the development of molecular simulation or computational chemistry tools * Basic knowledge of drug discovery processes and the application of molecular simulations in this field * Experience in deploying and orchestrating large-scale jobs using compute clusters or cloud-based infrastructures Working Location & Compensation: This is an office-based, hybrid role in our New York office. Employees are expected to work in the office at least 50% of the time. At Recursion, we believe that every employee should be compensated fairly. Based on the skill and level of experience required for this role, the estimated current annual base range for this role is $129,000 to $163,300. You will also be eligible for an annual bonus and equity compensation, as well as a comprehensive benefits package. #LI-EP1 The Values We Hope You Share: * We act boldly with integrity. We are unconstrained in our thinking, take calculated risks, and push boundaries, but never at the expense of ethics, science, or trust. * We care deeply and engage directly. Caring means holding a deep sense of responsibility and respect - showing up, speaking honestly, and taking action. * We learn actively and adapt rapidly. Progress comes from doing. We experiment, test, and refine, embracing iteration over perfection. * We move with urgency because patients are waiting. Speed isn't about rushing but about moving the needle every day. * We take ownership and accountability. Through ownership and accountability, we enable trust and autonomy-leaders take accountability for decisive action, and teams own outcomes together. * We are One Recursion. True cross-functional collaboration is about trust, clarity, humility, and impact. Through sharing, we can be greater than the sum of our individual capabilities. Our values underpin the employee experience at Recursion. They are the character and personality of the company demonstrated through how we communicate, support one another, spend our time, make decisions, and celebrate collectively. More About Recursion Recursion (NASDAQ: RXRX) is a clinical stage TechBio company leading the space by decoding biology to radically improve lives. Enabling its mission is the Recursion OS, a platform built across diverse technologies that continuously generate one of the world's largest proprietary biological and chemical datasets. Recursion leverages sophisticated machine-learning algorithms to distill from its dataset a collection of trillions of searchable relationships across biology and chemistry unconstrained by human bias. By commanding massive experimental scale - up to millions of wet lab experiments weekly - and massive computational scale - owning and operating one of the most powerful supercomputers in the world, Recursion is uniting technology, biology and chemistry to advance the future of medicine. Recursion is headquartered in Salt Lake City, where it is a founding member of BioHive, the Utah life sciences industry collective. Recursion also has offices in Toronto, Montréal, New York, London, Oxford area, and the San Francisco Bay area. Learn more at ****************** or connect on X (formerly Twitter) and LinkedIn. Recursion is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other characteristic protected under applicable federal, state, local, or provincial human rights legislation. Accommodations are available on request for candidates taking part in all aspects of the selection process. Recruitment & Staffing Agencies: Recursion Pharmaceuticals and its affiliate companies do not accept resumes from any source other than candidates. The submission of resumes by recruitment or staffing agencies to Recursion or its employees is strictly prohibited unless contacted directly by Recursion's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Recursion, and Recursion will not owe any referral or other fees. Our team will communicate directly with candidates who are not represented by an agent or intermediary unless otherwise agreed to prior to interviewing for the job.
    $129k-163.3k yearly Auto-Apply 20d ago
  • Research Associate II, Analytical Sciences (Contract)

    Oric Pharmaceuticals, Inc. 4.5company rating

    South San Francisco, CA jobs

    ORIC Pharmaceuticals is a clinical stage biopharmaceutical company dedicated to improving patients' lives by Overcoming Resistance In Cancer. ORIC's clinical stage product candidates include (1) rinzimetostat (ORIC-944), an allosteric inhibitor of the polycomb repressive complex 2 (PRC2) via the EED subunit, being developed for prostate cancer, and (2) enozertinib, a brain penetrant inhibitor that selectively targets EGFR exon 20, HER2 exon 20 and EGFR atypical mutations, being developed across multiple genetically defined cancers. Beyond these two product candidates, ORIC is also developing multiple precision medicines targeting other hallmark cancer resistance mechanisms. ORIC has offices in South San Francisco and San Diego, California. For more information, please go to ******************* and follow us on X or LinkedIn. We are seeking a highly motivated Research Associate II (Contractor) with a proven record of sustained laboratory achievement and innovation to join our growing PharmSci group at ORIC Pharmaceuticals. The selected candidate will provide lab support across various projects and teams; contribute to our shared mission of bringing new therapies to cancer patients. Job Description * Perform sample analysis using general laboratory techniques, such as weighing, pipetting, and operating laboratory instruments (HPLC, LC-MS, GC, UV-Vis, KF, dissolution apparatus, etc.). * Execute analysis with a solid understanding of the test procedures, underlying science and proper instrument operation, ensuring accurate and reliable results. * Utilize available software to control instruments, collect data, process and calculate results, and prepare comprehensive reports. * Maintain precise and comprehensive records of all analyses in a lab notebook, ensuring compliance with company standards and promoting traceability and consistency in data reporting. * Prepare test solutions, reagents, and samples for analysis, ensuring accuracy and strict adherence to written instructions and procedures. * Prepare presentation materials and clearly communicate research results to manager, and at internal/external meetings. * Work cross-functionally with Process Chemistry and Formulation Development colleagues. Qualifications * Requires a B.Sc. degree in chemistry with a minimum of 3 years of relevant research experience, or a M.Sc. degree with at least 1 year of hands-on pharmaceutical/biotech industry experience, or equivalent, in the field of new drug discovery and development. * Hands-on experience with laboratory techniques, including chromatography (e.g., HPLC, GC, LC/MS), spectroscopy (e.g., UV-Vis, FTIR), titration methods (e.g., Karl Fischer, acid-base), dissolution testing, particle size analysis (by laser diffraction), microscopy, and other compendial methods. * Experience using laboratory software to collect, analyze, and report data. This might include instrument control software (Chemstation, Empower, etc.) or data analysis programs (Excel, etc.). * Demonstrated ability to take initiative, ownership, problem identification, problem solving and input into experimental design aspects. * A proven record of sustained laboratory achievement and innovation. * Familiarity with industry guidelines such as ICH guidelines, USP requirements, FDA guidance, and good laboratory practices (GLP). * Exceptional safety and organizational skills and attention to detail when handling samples, recording data, and preparing reports. * Demonstrated ability to work independently and efficiently in a collaborative, fast-paced, integrated, multidisciplinary team environment. Additional Information The anticipated salary range for candidates who will work on-site at our South San Francisco location is between $45.00-$50.00 per hour. The final wage offered to a successful candidate will be dependent on several factors that may include, title, type and length of experience within the role, type and length of experience within the industry, education, geography, and other job-related factors. ORIC Pharmaceuticals, Inc. is an equal opportunity employer. ORIC does not discriminate based on race, color, religion, gender, sexual orientation, gender identity, age, national origin, disability status, protected veteran status, or any other legally protected characteristics.
    $45-50 hourly 13d ago
  • Neuroscience Research Scientist

    Recursion 4.2company rating

    Salt Lake City, UT jobs

    Your work will change lives. Including your own. The Impact You'll Make Be a key hands-on contributor to our neuroscience team, applying your deep expertise in advanced electrophysiology and neuropharmacology to characterize network dysfunction in neurodegenerative disease models. Generate high-quality, actionable data that our entire programs will build on. You'll use your skills with cellular models, including human iPSC-derived 2D and 3D models, to produce the functional readouts (e.g., MEA, calcium imaging and other neuropharmacology assays) that fuel our discovery pipeline. Collaborate closely with a cross-functional team of biologists and data scientists. You will play a vital role in designing experiments, analyzing complex neural datasets, and translating raw functional readouts into shared, actionable insights. Help our team grow and improve by bringing your pharma expertise and rigorous, detail-oriented approach to the lab. You'll help optimize assays, validate new systems, and share your knowledge to support the growth of colleagues in a collaborative setting. Contribute to a fast-paced, mission-driven environment where your ability to troubleshoot, communicate clearly, and work as part of a team is essential to our collective success. In this role, you will: Serve as a hands-on technical expert, executing advanced neuropharmacology and electrophysiology studies (e.g., multielectrode arrays, imaging assays) on human iPSC-derived neurons and 2D/3D neurodegenerative disease models. Independently design, develop, and optimize cell-based functional assays to characterize drug candidates and profile new model systems. Conduct rigorous analysis, signal processing, and troubleshooting of complex neuroscience datasets (e.g., electrical traces, local field potentials, calcium traces, pharmacodynamic modeling). Document and present experimental designs, data, and actionable insights to our cross-functional team to help drive program decisions. Manage key laboratory functions with high attention to detail, including coordinating any cross-functional lab work, monitoring inventory, ordering reagents, and basic equipment maintenance. The Team You'll Join You will be an integral member of our Neuro Team, a highly collaborative group united by a strong commitment to serving patients with devastating neurodegenerative diseases. Our team operates at the intersection of deep domain expertise and data-driven science. We are responsible for discovering targets and advancing new medicines by working to decode the complex biology of the human nervous system. To do this, we combine insights from our large-scale maps of biology with hypothesis-driven functional studies using advanced, human-relevant models. You will work cross-functionally in a highly matrixed environment, collaborating daily with experts in data science, computational biology, pharmacology, stem cell biology, and medicinal chemistry. Your hands-on expertise in electrophysiology and functional assays will be critical, providing the high-fidelity data and biological insights that validate our targets and drive our therapeutic programs forward. We thrive on open communication, intellectual curiosity, and a shared sense of mission. We are looking for a colleague who values rigorous science, brings a collaborative spirit, and is motivated to learn and grow with us as we tackle one of medicine's greatest challenges. The Experience You'll Need M.S. or B.S. in Neuroscience, Biology, or related field (Ph.D. not required) and 3-5 years of pharmaceutical or biotechnology experience with hands-on execution of advanced cellular neuropharmacology and electrophysiological studies, preferably within the context of neurodegenerative diseases. Direct hands-on experience with functional neuroscience techniques such as multielectrode arrays and other high-throughput ephys platforms to characterize drug candidates and profile novel cellular model systems. Hands-on expertise and proficiency with human cell-based translatable systems, including iPSC-derived neurons and 2D or 3D in vitro neurodegenerative disease models. Demonstrated ability to independently design, optimize, analyze and present data related to cell-based functional assays. Deep experience with electrical traces, local field potentials (LFP), or calcium imaging is highly desirable. Knowledge and ability to execute general molecular biology techniques and assays for downstream protein and RNA processing preferred. Working Location: This is a lab-based, hybrid role in our Salt Lake City office. Employees are expected to work in the office/lab at least 80% of the time. At Recursion, we believe that every employee should be compensated fairly. Based on the skill and level of experience required for this role, the estimated current annual base range for this role is $94,600-$118,600. You will also be eligible for an annual bonus and equity compensation, as well as a comprehensive benefits package. #LI-BO1 The Values We Hope You Share: We act boldly with integrity. We are unconstrained in our thinking, take calculated risks, and push boundaries, but never at the expense of ethics, science, or trust. We care deeply and engage directly. Caring means holding a deep sense of responsibility and respect - showing up, speaking honestly, and taking action. We learn actively and adapt rapidly. Progress comes from doing. We experiment, test, and refine, embracing iteration over perfection. We move with urgency because patients are waiting. Speed isn't about rushing but about moving the needle every day. We take ownership and accountability. Through ownership and accountability, we enable trust and autonomy-leaders take accountability for decisive action, and teams own outcomes together. We are One Recursion. True cross-functional collaboration is about trust, clarity, humility, and impact. Through sharing, we can be greater than the sum of our individual capabilities. Our values underpin the employee experience at Recursion. They are the character and personality of the company demonstrated through how we communicate, support one another, spend our time, make decisions, and celebrate collectively. More About Recursion Recursion (NASDAQ: RXRX) is a clinical stage TechBio company leading the space by decoding biology to radically improve lives. Enabling its mission is the Recursion OS, a platform built across diverse technologies that continuously generate one of the world's largest proprietary biological and chemical datasets. Recursion leverages sophisticated machine-learning algorithms to distill from its dataset a collection of trillions of searchable relationships across biology and chemistry unconstrained by human bias. By commanding massive experimental scale - up to millions of wet lab experiments weekly - and massive computational scale - owning and operating one of the most powerful supercomputers in the world, Recursion is uniting technology, biology and chemistry to advance the future of medicine. Recursion is headquartered in Salt Lake City, where it is a founding member of BioHive, the Utah life sciences industry collective. Recursion also has offices in Toronto, Montréal, New York, London, Oxford area, and the San Francisco Bay area. Learn more at ****************** or connect on X (formerly Twitter) and LinkedIn. Recursion is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other characteristic protected under applicable federal, state, local, or provincial human rights legislation. Accommodations are available on request for candidates taking part in all aspects of the selection process. Recruitment & Staffing Agencies: Recursion Pharmaceuticals and its affiliate companies do not accept resumes from any source other than candidates. The submission of resumes by recruitment or staffing agencies to Recursion or its employees is strictly prohibited unless contacted directly by Recursion's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Recursion, and Recursion will not owe any referral or other fees. Our team will communicate directly with candidates who are not represented by an agent or intermediary unless otherwise agreed to prior to interviewing for the job.
    $94.6k-118.6k yearly Auto-Apply 60d+ ago
  • Staff Computational Biologist, Neuroscience

    Recursion Pharmaceuticals 4.2company rating

    New York, NY jobs

    Your work will change lives. Including your own. The Impact You'll Make As a key member of Recursion's partnership-facing data science team, you will be at the forefront of reimagining drug discovery from first principles using Recursion's massive data and compute capabilities. As senior computational biologist, you will be supporting a portfolio of partnership preclinical drug programs and be responsible for designing and executing analyses to support target nomination, validation, and early programs in neuroscience diseases. You will integrate layers of Recursion platform data (phenomics, transcriptomics, proteomics, etc) to validate the link between target and disease biology and to propose targets and early programs in novel areas of neuroscience. You will partner with biologists and medicinal chemists to build supporting data packets for targets from our phenomic maps, target screens, and partnered patient data sets. You will also collaborate with computational scientists from across the organization to develop, deploy, and scale novel approaches to: 1) translational validation in hit to lead, 2) mechanism-of-action identification/de-risking, and 3) build evidence for patient connectivity to match the targets we are validating and medicines we are creating to the patients who need them. In this role, you will: * Deliver biological insights on therapeutic candidates and disease biology from the analysis of high-dimensional (phenomics, transcriptomics, proteomics, patient-derived) datasets that support clinical development planning * Evaluate the biological and molecular evidence for therapeutic hypotheses and accelerate drug program progression into the clinic * Synthesize diverse datasets (internal and external) to generate and evaluate hypotheses for drug discovery, biomarker development, mechanism of action and target population identification * Present data analysis to decision makers and stakeholders in a clear and compelling way that drives toward getting medicines to patients * Assess new data sources, develop and scale new analysis methods, and support key program decisions with the ultimate goal of bringing life-changing therapies to patients at unprecedented speed * Industrialize analysis approaches to not only solve for the current project, but also to accelerate future projects and scale the impact that we can have * Collaborate cross-functionally with Recursion's data science, biology, medicinal chemistry, and platform, teams to further advance Recursion's ability to interpret and translate large-scale data assets into therapeutic programs The Team You'll Join Our group is a bold, agile, diverse collective of computational drug discovery scientists and data scientists deeply focused on the singular goal of bringing new therapeutics into the clinic at an accelerated pace. We are a computational group that spans precision oncology, neuroscience, and I&I (immunology and inflammation), and focuses on advancing novel, targeted therapies for these disease areas. We partner closely with our biologists and medicinal chemists to design and execute impactful and decisional data analysis for multiple programs. We are responsible for data strategy across the portfolio and supported by computational leadership in designing scalable and reproducible experiments that serve to advance multiple programs within the portfolio. Our team collaborates extensively with computational biologists in other therapeutic areas (immunology, oncology, etc.) as well as data scientists and engineers from our core platform teams to provide a strong network of feedback and support. The Experience You'll Need * PhD in a relevant field (computational biology, systems biology, bioinformatics, neuroscience, etc.) with a very strong computational focus and 5+ years of experience in biotech or pharma industry OR MS in a relevant field * Experience applying computational methods (including probabilistic, statistical, and/or machine learning techniques) to analyze and integrate matched human clinical and molecular data in a high-level programming language such as Python or R * Deep expertise in the analysis and data integration of one or more 'omics data modalities (phenomics, transcriptomics, proteomics, genomics) and/or human clinical data * Exceptional data visualization skills * Excellent cross-functional communication skills, including an ability to explain complex scientific concepts to a variety of audiences using a combination of plots, documents, and presentations Nice To Have: * Strong understanding of patient genetics and historical druggability of disease-relevant pathways, including experience working with patient data * Experience in efficiently advancing drug programs from proof of concept and into clinical development * Experience with neuroscience clinical trial biomarker analysis * Experience working as part of partnerships or client facing (consulting) teams Working Location & Compensation: This is an office-based, hybrid role in either our Salt Lake City or New York City offices. Employees are expected to work in the office at least 50% of the time. At Recursion, we believe that every employee should be compensated fairly. Based on the skill and level of experience required for this role, the estimated current annual base range for this role is $200,600 to $238,400. You will also be eligible for an annual bonus and equity compensation, as well as a comprehensive benefits package. #LI-EP1 The Values We Hope You Share: * We act boldly with integrity. We are unconstrained in our thinking, take calculated risks, and push boundaries, but never at the expense of ethics, science, or trust. * We care deeply and engage directly. Caring means holding a deep sense of responsibility and respect - showing up, speaking honestly, and taking action. * We learn actively and adapt rapidly. Progress comes from doing. We experiment, test, and refine, embracing iteration over perfection. * We move with urgency because patients are waiting. Speed isn't about rushing but about moving the needle every day. * We take ownership and accountability. Through ownership and accountability, we enable trust and autonomy-leaders take accountability for decisive action, and teams own outcomes together. * We are One Recursion. True cross-functional collaboration is about trust, clarity, humility, and impact. Through sharing, we can be greater than the sum of our individual capabilities. Our values underpin the employee experience at Recursion. They are the character and personality of the company demonstrated through how we communicate, support one another, spend our time, make decisions, and celebrate collectively. More About Recursion Recursion (NASDAQ: RXRX) is a clinical stage TechBio company leading the space by decoding biology to radically improve lives. Enabling its mission is the Recursion OS, a platform built across diverse technologies that continuously generate one of the world's largest proprietary biological and chemical datasets. Recursion leverages sophisticated machine-learning algorithms to distill from its dataset a collection of trillions of searchable relationships across biology and chemistry unconstrained by human bias. By commanding massive experimental scale - up to millions of wet lab experiments weekly - and massive computational scale - owning and operating one of the most powerful supercomputers in the world, Recursion is uniting technology, biology and chemistry to advance the future of medicine. Recursion is headquartered in Salt Lake City, where it is a founding member of BioHive, the Utah life sciences industry collective. Recursion also has offices in Toronto, Montréal, New York, London, Oxford area, and the San Francisco Bay area. Learn more at ****************** or connect on X (formerly Twitter) and LinkedIn. Recursion is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other characteristic protected under applicable federal, state, local, or provincial human rights legislation. Accommodations are available on request for candidates taking part in all aspects of the selection process. Recruitment & Staffing Agencies: Recursion Pharmaceuticals and its affiliate companies do not accept resumes from any source other than candidates. The submission of resumes by recruitment or staffing agencies to Recursion or its employees is strictly prohibited unless contacted directly by Recursion's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Recursion, and Recursion will not owe any referral or other fees. Our team will communicate directly with candidates who are not represented by an agent or intermediary unless otherwise agreed to prior to interviewing for the job.
    $200.6k-238.4k yearly Auto-Apply 5d ago
  • Health Economics & Outcomes Research Associate Director (HYBRID)

    Vertex Pharmaceuticals 4.6company rating

    Boston, MA jobs

    Vertex is seeking a talented and motivated individual to join its Global Health Economics & Outcomes Research (HEOR) group based in Boston's Seaport District. The Health Economics & Outcomes Research Associate Director will participate in the shaping and execution of HEOR strategies that optimize the value proposition for Vertex's Cystic Fibrosis and early pipeline assets through each stage of development, including launch and post-launch phases. This position reports to the Senior Director HEOR, CF and Early Pipeline. Key Duties and Responsibilities: Leads execution of complex HEOR evidence generation studies, including: prospective and retrospective observational studies, systematic literature reviews, cost-effective analyses and budget impact models, Indirect Treatment Comparisons, COA strategy, PRO measure development and validation, as needed, to support the asset value Effectively leads external research partners to ensure robust scientific methods are applied to study design and execution and in compliance with all local regulations; is accountable for study design, data analysis and the quality of the evidence produced. Excellent project management is a pre-requisite to ensure studies delivered on time and within budget. Collaborates with the medical communications teams on publication strategy and ensure that dissemination of HEOR evidence is timely and has maximum impact Partners and works closely with Global Pricing and Market Access to support development of product value proposition/value messaging and co-lead development of robust Global launch deliverables (e.g., global value dossier) Knowledge and Skills: Strong track record of publication in peer-reviewed journals Strong background in clinical outcome assessment (COA) measurement strategy; experience in PRO development/validation and qualitative research methodology Technical expertise in HEOR; able to formulate and lead creative research projects and ensure conduct is technically and scientifically rigorous and reflects best HEOR practices Strong verbal and written communications skills, including presentation skills to communicate difficult concepts and persuade others; comfortable communicating complex concepts and adapting presentation style to a variety of audiences Ability to apply knowledge of US healthcare system, global health technology appraisal requirements, and clinical development, to identify evidence gaps and formulate evidence generation strategies Understanding of the legal and regulatory environment of the pharmaceutical industry, with spotless history of compliance and ethical workplace conduct Education and Experience: Advanced degree (PhD, MD, Master's degree, MPH, or PharmD) in a relevant discipline. Typically requires 8 years of experience, with substantial background in HEOR, or the equivalent combination of education and experience Pay Range: $172,000 - $258,000 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com
    $74k-97k yearly est. Auto-Apply 60d+ ago
  • Global Health Economics & Outcomes Research (HEOR) Associate Director (HYBRID)

    Vertex Pharmaceuticals 4.6company rating

    Boston, MA jobs

    Vertex is a global biotechnology company on the forefront of scientific innovation. In addition to marketed therapies in cystic fibrosis (CF), sickle cell disease, beta-thalassemia, and moderate-to-severe acute pain , our research pipeline spans more than a dozen programs targeting the underlying mechanisms of serious diseases. Vertex is seeking a talented and motivated individual to join its Global Health Economics & Outcomes Research (HEOR) group based in Boston's Seaport District. The HEOR Associate Director will participate in the shaping and execution of HEOR strategies that optimize the value proposition for Vertex's CF and early pipeline assets through each stage of development, including launch and post-launch phases. This position reports to the Executive Director HEOR, CF and Early Pipeline. Key Duties and Responsibilities: Leads execution of complex HEOR evidence generation studies, with focus on prospective and retrospective observational studies, COA strategy, and PRO measure development and validation, as well as systematic literature reviews, cost-effective analyses and budget impact models, indirect treatment comparisons, as needed, to support the asset value. Effectively leads external research partners to ensure robust scientific methods are applied to study design and execution and in compliance with all local regulations; is accountable for study design, data analysis and the quality of the evidence produced. Excellent project management is a pre-requisite to ensure studies delivered on time and within budget. Collaborates with the medical communications teams on publication strategy and ensure that dissemination of HEOR evidence is timely and has maximum impact Partners and works closely with Global Pricing and Market Access to support development of product value proposition/value messaging and co-lead development of robust Global launch deliverables (e.g., global value dossier) Knowledge and Skills: Strong track record of publication in peer-reviewed journals Strong background in clinical outcome assessment (COA) measurement strategy; experience in PRO development/validation and qualitative research methodology Technical expertise in HEOR with able to formulate and lead creative research projects and ensure conduct is technically and scientifically rigorous and reflects best HEOR practices; hands-on experience with prospective and site-based research is desired Strong verbal and written communications skills, including presentation skills to communicate difficult concepts and persuade others; comfortable communicating complex concepts and adapting presentation style to a variety of audiences Excellent project and people management skills to oversee vendors and internal project team, while aligning with cross-functional partners to ensure successful project execution, on timelines and budgets Ability to apply knowledge of US healthcare system, global health technology appraisal requirements, and clinical development, to identify evidence gaps and formulate evidence generation strategies Understanding of the legal and regulatory environment of the pharmaceutical industry, with spotless history of compliance and ethical workplace conduct Education and Experience: Advanced degree (PhD, MD, Master's degree, MPH, or PharmD) in a relevant discipline. Typically requires 8+ years of relevant experience, with substantial background in a Global HEOR role in a pharmaceutical/biotech setting, or the equivalent combination of education and experience Pay Range: $176,000 - $264,000 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com
    $74k-97k yearly est. Auto-Apply 5d ago
  • Staff Computational Biologist, Neuroscience

    Recursion 4.2company rating

    Saltaire, NY jobs

    Your work will change lives. Including your own. The Impact You'll Make As a key member of Recursion's partnership-facing data science team, you will be at the forefront of reimagining drug discovery from first principles using Recursion's massive data and compute capabilities. As senior computational biologist, you will be supporting a portfolio of partnership preclinical drug programs and be responsible for designing and executing analyses to support target nomination, validation, and early programs in neuroscience diseases. You will integrate layers of Recursion platform data (phenomics, transcriptomics, proteomics, etc) to validate the link between target and disease biology and to propose targets and early programs in novel areas of neuroscience. You will partner with biologists and medicinal chemists to build supporting data packets for targets from our phenomic maps, target screens, and partnered patient data sets. You will also collaborate with computational scientists from across the organization to develop, deploy, and scale novel approaches to: 1) translational validation in hit to lead, 2) mechanism-of-action identification/de-risking, and 3) build evidence for patient connectivity to match the targets we are validating and medicines we are creating to the patients who need them. In this role, you will: Deliver biological insights on therapeutic candidates and disease biology from the analysis of high-dimensional (phenomics, transcriptomics, proteomics, patient-derived) datasets that support clinical development planning Evaluate the biological and molecular evidence for therapeutic hypotheses and accelerate drug program progression into the clinic Synthesize diverse datasets (internal and external) to generate and evaluate hypotheses for drug discovery, biomarker development, mechanism of action and target population identification Present data analysis to decision makers and stakeholders in a clear and compelling way that drives toward getting medicines to patients Assess new data sources, develop and scale new analysis methods, and support key program decisions with the ultimate goal of bringing life-changing therapies to patients at unprecedented speed Industrialize analysis approaches to not only solve for the current project, but also to accelerate future projects and scale the impact that we can have Collaborate cross-functionally with Recursion's data science, biology, medicinal chemistry, and platform, teams to further advance Recursion's ability to interpret and translate large-scale data assets into therapeutic programs The Team You'll Join Our group is a bold, agile, diverse collective of computational drug discovery scientists and data scientists deeply focused on the singular goal of bringing new therapeutics into the clinic at an accelerated pace. We are a computational group that spans precision oncology, neuroscience, and I&I (immunology and inflammation), and focuses on advancing novel, targeted therapies for these disease areas. We partner closely with our biologists and medicinal chemists to design and execute impactful and decisional data analysis for multiple programs. We are responsible for data strategy across the portfolio and supported by computational leadership in designing scalable and reproducible experiments that serve to advance multiple programs within the portfolio. Our team collaborates extensively with computational biologists in other therapeutic areas (immunology, oncology, etc.) as well as data scientists and engineers from our core platform teams to provide a strong network of feedback and support. The Experience You'll Need PhD in a relevant field (computational biology, systems biology, bioinformatics, neuroscience, etc.) with a very strong computational focus and 5+ years of experience in biotech or pharma industry OR MS in a relevant field Experience applying computational methods (including probabilistic, statistical, and/or machine learning techniques) to analyze and integrate matched human clinical and molecular data in a high-level programming language such as Python or R Deep expertise in the analysis and data integration of one or more ‘omics data modalities (phenomics, transcriptomics, proteomics, genomics) and/or human clinical data Exceptional data visualization skills Excellent cross-functional communication skills, including an ability to explain complex scientific concepts to a variety of audiences using a combination of plots, documents, and presentations Nice To Have: Strong understanding of patient genetics and historical druggability of disease-relevant pathways, including experience working with patient data Experience in efficiently advancing drug programs from proof of concept and into clinical development Experience with neuroscience clinical trial biomarker analysis Experience working as part of partnerships or client facing (consulting) teams Working Location & Compensation: This is an office-based, hybrid role in either our Salt Lake City or New York City offices. Employees are expected to work in the office at least 50% of the time. At Recursion, we believe that every employee should be compensated fairly. Based on the skill and level of experience required for this role, the estimated current annual base range for this role is $200,600 to $238,400. You will also be eligible for an annual bonus and equity compensation, as well as a comprehensive benefits package. #LI-EP1 The Values We Hope You Share: We act boldly with integrity. We are unconstrained in our thinking, take calculated risks, and push boundaries, but never at the expense of ethics, science, or trust. We care deeply and engage directly. Caring means holding a deep sense of responsibility and respect - showing up, speaking honestly, and taking action. We learn actively and adapt rapidly. Progress comes from doing. We experiment, test, and refine, embracing iteration over perfection. We move with urgency because patients are waiting. Speed isn't about rushing but about moving the needle every day. We take ownership and accountability. Through ownership and accountability, we enable trust and autonomy-leaders take accountability for decisive action, and teams own outcomes together. We are One Recursion. True cross-functional collaboration is about trust, clarity, humility, and impact. Through sharing, we can be greater than the sum of our individual capabilities. Our values underpin the employee experience at Recursion. They are the character and personality of the company demonstrated through how we communicate, support one another, spend our time, make decisions, and celebrate collectively. More About Recursion Recursion (NASDAQ: RXRX) is a clinical stage TechBio company leading the space by decoding biology to radically improve lives. Enabling its mission is the Recursion OS, a platform built across diverse technologies that continuously generate one of the world's largest proprietary biological and chemical datasets. Recursion leverages sophisticated machine-learning algorithms to distill from its dataset a collection of trillions of searchable relationships across biology and chemistry unconstrained by human bias. By commanding massive experimental scale - up to millions of wet lab experiments weekly - and massive computational scale - owning and operating one of the most powerful supercomputers in the world, Recursion is uniting technology, biology and chemistry to advance the future of medicine. Recursion is headquartered in Salt Lake City, where it is a founding member of BioHive, the Utah life sciences industry collective. Recursion also has offices in Toronto, Montréal, New York, London, Oxford area, and the San Francisco Bay area. Learn more at ****************** or connect on X (formerly Twitter) and LinkedIn. Recursion is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other characteristic protected under applicable federal, state, local, or provincial human rights legislation. Accommodations are available on request for candidates taking part in all aspects of the selection process. Recruitment & Staffing Agencies: Recursion Pharmaceuticals and its affiliate companies do not accept resumes from any source other than candidates. The submission of resumes by recruitment or staffing agencies to Recursion or its employees is strictly prohibited unless contacted directly by Recursion's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Recursion, and Recursion will not owe any referral or other fees. Our team will communicate directly with candidates who are not represented by an agent or intermediary unless otherwise agreed to prior to interviewing for the job.
    $200.6k-238.4k yearly Auto-Apply 4d ago
  • Associate Principal Scientist - Downstream Vaccines and Advanced Biotechnologies Process R&D

    MSD 4.6company rating

    Point, PA jobs

    Applications are sought for an opportunity in the Vaccine and Advanced Biotechnologies (VAX) Process R&D department, which is part of the our Research & Development Division. The individual will support our Company's downstream process development efforts for Vaccine programs at West Point, PA. Vaccines and Advanced Biotechnologies (VAX) Process R&D is responsible for the development and clinical manufacturing of Drug Substance (DS) and Drug Product Intermediates (DPI) for the vaccine and advanced therapy pipeline, spanning from preclinical to commercialization stages. We are part of the Process R&D organization, which enables modality-agnostic DS/DPI process development and clinical manufacturing for our company's pipeline. Our vaccines downstream process development team develops safe, scalable, robust, cost-effective downstream processes that enable clinical and commercial manufacture of vaccines and adjuvants across all vaccine modalities. We are seeking an innovative, highly motivated, and experienced Associate Principal Scientist to join us at our research and development site in West Point, PA. The candidate will be responsible for scientific/technical leadership of a bioconjugation process development team, and will also be a critical member of cross-functional program/project teams. This role will require frequent collaboration with cross-functional teams including Analytical, Formulation, Process Chemistry, Enabling Technologies, and Manufacturing colleagues. The candidate should have a strong background in downstream bioprocess/bioconjugation design, including reaction steps, filtration (tangential and normal flow) and column chromatography. Preferably, the candidate will have a strong background in biomolecule conjugation techniques and conjugate modalities (e.g., conjugate vaccines, antibody-drug conjugates). Primary responsibilities include, but are not limited to: Lead downstream process design and development for conjugate vaccine candidates. Design, execute, and analyze process development experiments to maximize conjugate vaccine production processes, thereby de-risking later stage development and tech transfer. Represent functional area in cross-functional and strategic teams engaged in vaccine development. Lead tech transfer of vaccine bioconjugation processes for clinical and commercial manufacture. Serve as scientific/technical mentor for junior staff, providing technical guidance in the various aspects of downstream bioprocess/bioconjugation development. Support strategic initiatives and innovation in the areas of vaccine and advanced biotechnology process development. Analysis of experiments through analytical techniques including HPLC, light scattering, and spectroscopy. Data interpretation and presentation, manuscript/patent preparation. Education Minimum Requirement: BS, MS or PhD in engineering or bio/chemical sciences: Chemical Engineering, Bioengineering, Biomedical Engineering, Chemistry, Biochemistry, Molecular Biology, Biotechnology For BS candidates, at least eight (8) years of experience in a pharmaceutical or biotechnology-related position For MS candidates, at least five (5) years of experience in a pharmaceutical or biotechnology-related position For PhD candidates, at least three (3) years of experience in a pharmaceutical or biotechnology-related position Required Experience and Skills: Strong scientific and hands-on understanding of downstream bioprocess/bioconjugation unit operations, biotherapeutic and/or vaccine process development and sound understanding of scale-up principles. At least five (5) years of hands-on laboratory experience in downstream bioprocess/bioconjugation development. Prior experience with statistical design of experiments (DOE) and/or algorithmic process optimization. Strong understanding of, or hands-on experience in, cGMP manufacturing. Ability to work effectively both independently and in a team-focused environment. Well-developed organizational, record-keeping, and timeline/resource-mapping skills. Preferred Experience and Skills: Experience with biomolecule conjugation (e.g., conjugate vaccines, antibody-drug conjugates), conjugation chemistry and downstream bioconjugate processing. Experience in leading technical development teams and mentoring others. Experience in authoring and reviewing CMC regulatory documentation. Experience with process and technology transfer. The successful candidate will be expected to demonstrate the ability to communicate results of their work in both verbal and written formats. They are also expected to demonstrate flexibility in responding to changing priorities or dealing with unexpected events. In addition to the core responsibilities outlined above, the candidate will be expected to comply with all required training and maintain a focused attention on laboratory safety for themselves and their team. Position may require working with infectious agents, pathogens, and/or potent compounds with appropriate engineering controls and PPE. Some travel or off-hours work may be required. #PRD Required Skills: Accountability, Accountability, Animal Vaccination, Antibody Drug Conjugates (ADC), Bioconjugation, Biomedical Engineering, Biomedical Sciences, Biotechnology, Cell Line Development, Chemical Engineering, Chemical Technology, Column Chromatography, Detail-Oriented, Downstream Process Development, Drug Delivery Technology, Drug Development, Expression Vectors, Immunochemistry, Innovation, Interpersonal Relationships, Laboratory Safety, Leading Project Teams, Machine Learning (ML), Molecular Biology, Pharmaceutical Formulations {+ 4 more} Preferred Skills: Current Employees apply HERE Current Contingent Workers apply HERE US and Puerto Rico Residents Only: Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process. As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit: EEOC Know Your Rights EEOC GINA Supplement We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively. Learn more about your rights, including under California, Colorado and other US State Acts U.S. Hybrid Work Model Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”. The salary range for this role is $142,400.00 - $224,100.00 This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee's position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs. The successful candidate will be eligible for annual bonus and long-term incentive, if applicable. We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at ******************************************************* You can apply for this role through **************************** (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting. San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance Search Firm Representatives Please Read Carefully Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. Employee Status: Regular Relocation: Domestic VISA Sponsorship: No Travel Requirements: 10% Flexible Work Arrangements: Not Applicable Shift: Not Indicated Valid Driving License: No Hazardous Material(s): N/A Job Posting End Date: 02/10/2026 *A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.
    $62k-87k yearly est. Auto-Apply 7d ago
  • Senior Computational Biologist, Immunology

    Recursion Pharmaceuticals 4.2company rating

    New York, NY jobs

    Your work will change lives. Including your own. The Impact You'll Make As a key member of Recursion's partnership-facing data science team, you will be at the forefront of reimagining drug discovery from first principles using Recursion's massive data and compute capabilities. As senior computational biologist, you will be supporting partnership portfolio of preclinical drug programs and be responsible for designing and executing analyses to support target nomination, validation, and early programs in immunology and inflammation (I&I) diseases, translationally validates disease contexts in hit-to-lead, and accelerates in vivo work in lead optimization. You will integrate layers of Recursion platform data (phenomics, transcriptomics, proteomics, etc) to validate the link between target and disease biology and to propose targets and early programs in novel areas of immunology and inflammation. You will partner with biologists and medicinal chemists to build supporting data packets for targets from our phenomic maps, target screens, and partnered patient data sets. You will also collaborate with computational scientists from across the organization to develop, deploy, and scale novel approaches to: 1) translational validation in hit to lead, 2) mechanism-of-action identification/de-risking , and 3) build evidence for patient connectivity to match the medicines we are creating to the patients who need them. In this role, you will: * Deliver biological insights on therapeutic candidates and disease biology from the analysis of high-dimensional (phenomics, transcriptomics, proteomics, patient-derived) datasets that support clinical development planning * Evaluate the molecular evidence for therapeutic hypotheses and accelerate drug program progression into the clinic * Present data analysis to decision makers and stakeholders in a clear and compelling way that drives toward getting medicines to patients * Assess new data sources, develop and scale new analysis methods, and support key program decisions with the ultimate goal of bringing life-changing therapies to patients at unprecedented speed * Industrialize analysis approaches to not only solve for the current project, but also to accelerate future projects and scale the impact that we can have * Collaborate cross-functionally with Recursion's data science, biology, medicinal chemistry, and platform, teams to further advance Recursion's ability to interpret and translate large-scale data assets into therapeutic programs The Team You'll Join Our group is a bold, agile, diverse collective of computational drug discovery scientists deeply focused on the singular goal of bringing new therapeutics into the clinic at an accelerated pace. We are a computational group that spans precision oncology, I&I (immunology and inflammation), and neuroscience and focuses on advancing novel, targeted therapies for these disease areas. We partner closely with our biologists and medicinal chemists to design and execute impactful and decisional data analysis for multiple programs. We are responsible for data strategy across the portfolio and supported by computational leadership in designing scalable and reproducible experiments that serve to advance multiple programs within the portfolio. Our team collaborates extensively with computational biologists in other therapeutic areas (neurobiology, oncology, etc.) as well as data scientists and engineers from our core platform teams to provide a strong network of feedback and support. The Experience You'll Need * PhD in a relevant field (computational biology, systems biology, bioinformatics, immunology/inflammation biology, immuno-oncology, etc.) with a very strong computational focus and 3+ years of experience in biotech or pharma industry OR MS in a relevant field and 5+ years of experience in biotech or pharma industry solving fundamental problems in immunology or drug discovery * Experience with one or more immunology or inflammation disease areas; * Experience applying computational methods (including probabilistic, statistical, and/or machine learning techniques) to analyze and integrate matched human clinical and molecular data in a high-level programming language such as Python or R * Deep expertise in the analysis and data integration of one or more 'omics data modalities (phenomics, transcriptomics, proteomics, genomics),Exceptional data visualization skills * Excellent cross-functional communication skills, including an ability to explain complex scientific concepts to a variety of audiences using a combination of plots, documents, and presentations Nice To Have: * Strong understanding of patient genetics and historical druggability of disease-relevant pathways, including experience working with patient data * Experience in efficiently advancing drug programs from proof of concept and into clinical development * Experience with immunology and inflammation clinical trial biomarker analysis Working Location & Compensation: This is an office-based, hybrid role in either our Salt Lake City, UT or New York City, NY offices. Employees are expected to work in the office at least 50% of the time. At Recursion, we believe that every employee should be compensated fairly. Based on the skill and level of experience required for this role, the estimated current annual base range for this role is $151,800 to $216,300 (USD). You will also be eligible for an annual bonus and equity compensation, as well as a comprehensive benefits package. #LI-EP1 The Values We Hope You Share: * We act boldly with integrity. We are unconstrained in our thinking, take calculated risks, and push boundaries, but never at the expense of ethics, science, or trust. * We care deeply and engage directly. Caring means holding a deep sense of responsibility and respect - showing up, speaking honestly, and taking action. * We learn actively and adapt rapidly. Progress comes from doing. We experiment, test, and refine, embracing iteration over perfection. * We move with urgency because patients are waiting. Speed isn't about rushing but about moving the needle every day. * We take ownership and accountability. Through ownership and accountability, we enable trust and autonomy-leaders take accountability for decisive action, and teams own outcomes together. * We are One Recursion. True cross-functional collaboration is about trust, clarity, humility, and impact. Through sharing, we can be greater than the sum of our individual capabilities. Our values underpin the employee experience at Recursion. They are the character and personality of the company demonstrated through how we communicate, support one another, spend our time, make decisions, and celebrate collectively. More About Recursion Recursion (NASDAQ: RXRX) is a clinical stage TechBio company leading the space by decoding biology to radically improve lives. Enabling its mission is the Recursion OS, a platform built across diverse technologies that continuously generate one of the world's largest proprietary biological and chemical datasets. Recursion leverages sophisticated machine-learning algorithms to distill from its dataset a collection of trillions of searchable relationships across biology and chemistry unconstrained by human bias. By commanding massive experimental scale - up to millions of wet lab experiments weekly - and massive computational scale - owning and operating one of the most powerful supercomputers in the world, Recursion is uniting technology, biology and chemistry to advance the future of medicine. Recursion is headquartered in Salt Lake City, where it is a founding member of BioHive, the Utah life sciences industry collective. Recursion also has offices in Toronto, Montréal, New York, London, Oxford area, and the San Francisco Bay area. Learn more at ****************** or connect on X (formerly Twitter) and LinkedIn. Recursion is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other characteristic protected under applicable federal, state, local, or provincial human rights legislation. Accommodations are available on request for candidates taking part in all aspects of the selection process. Recruitment & Staffing Agencies: Recursion Pharmaceuticals and its affiliate companies do not accept resumes from any source other than candidates. The submission of resumes by recruitment or staffing agencies to Recursion or its employees is strictly prohibited unless contacted directly by Recursion's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Recursion, and Recursion will not owe any referral or other fees. Our team will communicate directly with candidates who are not represented by an agent or intermediary unless otherwise agreed to prior to interviewing for the job.
    $151.8k-216.3k yearly Auto-Apply 58d ago
  • Senior Computational Biologist - Translational and Clinical Biomarkers

    Recursion Pharmaceuticals 4.2company rating

    New York, NY jobs

    Your work will change lives. Including your own. The Impact You'll Make As a key member of Recursion's portfolio-facing data science team, you will be at the forefront of reimagining drug discovery from first principles using Recursion's massive data and compute capabilities. You will be the primary computational lead for multiple IND and clinical stage drug development programs and will be expected to use platform and patient data to advance our most promising therapeutic candidates through clinical trials. You will be responsible for the evaluation of therapeutic hypotheses using internal and external data to identify candidate biomarkers to measure in translational studies and in phase I-II clinical trials. This is a highly collaborative role: you will partner with biologists, clinicians, platform and data engineers, and translational experts to develop and scale methods that bring patient insights and reverse translation to the forefront of our medicines portfolio. The ideal candidate has strong stakeholder management, the ability to independently scope and prioritize with ambiguous or conflicting information, and is motivated to look under every stone to do the right thing for patients. In this role, you will: * Evaluate the molecular evidence for predictive and PD biomarker hypotheses in translational models and clinical samples (DNA, RNA, ct DNA, and novel exploratory modalities) * Pilot novel methods for patient stratification and indication selection or expansion * Deliver biological insights on therapeutic candidates and disease biology from the analysis of high dimensional (phenomics, transcriptomics, patient-derived) datasets * Present data analysis to decision makers and stakeholders in a clear and compelling way that drives toward getting medicines to patients * Industrialize analysis approaches to not only solve for the current project, but also accelerate future projects and scale the impact that we can have * Collaborate cross-functionally with Recursion's data science, platform, ML and clinical teams to further advance Recursion's ability to leverage our own clinical data in meta-analysis, hypothesis generation, and reverse translation The Team You'll Join Our group is a bold, agile, diverse collective of computational drug discovery scientists deeply focused on the singular goal of bringing new therapeutics into the clinic at an accelerated pace. You will work extensively with scientists across the organization to advance milestones, provide insights, and drive decisions that advance Recursion's capabilities and increase our likelihood of success. Essential attributes for this role include a bold, execution-first attitude and passion for deploying rigorous science to develop life-changing medicines. We partner closely with biologists, translational scientists, and clinicians to design and execute decisional data analysis for multiple programs. We are responsible for data strategy across the portfolio and are supported by computational leadership in designing scalable and reproducible experiments that advance multiple programs at once. Our team works closely with computational biologists in other therapeutic areas (neurobiology, immunology and inflammatory diseases, etc.) as well as data scientists and engineers from our core platform teams to provide a strong network of feedback and support. The Experience You'll Need * PhD in a relevant field (computational biology, systems biology, bioinformatics, cancer biology, immuno-oncology, etc.) with a very strong computational focus and 3+ years of experience in biotech or pharma industry OR MS in a relevant field and 5+ years of experience in biotech or pharma industry solving fundamental problems in oncology or drug discovery * Experience with high dimensional patient biomarker data from clinical trials in oncology * Strong understanding of patient genetics and druggability of disease relevant pathways * Experience applying computational methods (including probabilistic, statistical, and/or machine learning techniques) to analyze and integrate complex biological and/or human clinical data in a high level programming language such as Python or R * Deep expertise in the analysis and data integration of two or more 'omics data modalities (phenomics, transcriptomics, proteomics, genomics) including experience with matched clinical and molecular patient data * Exceptional data visualization skills * Excellent cross-functional communication skills, including an ability to explain complex scientific concepts to a variety of audiences using a combination of plots, documents, and presentations Nice To Have: * Experience with late stage drug discovery and IND submission * Experience collaborating cross-functionally with biometrics, statistical sciences and clinical pharmacology departments Working Location & Compensation: This is an office-based, hybrid role in either our Salt Lake City, UT or New York City, NY offices. Employees are expected to work in the office at least 50% of the time. At Recursion, we believe that every employee should be compensated fairly. Based on the skill and level of experience required for this role, the estimated current annual base range for this role is $151,800 to $216,300 (USD). You will also be eligible for an annual bonus and equity compensation, as well as a comprehensive benefits package. #LI-EP1 The Values We Hope You Share: * We act boldly with integrity. We are unconstrained in our thinking, take calculated risks, and push boundaries, but never at the expense of ethics, science, or trust. * We care deeply and engage directly. Caring means holding a deep sense of responsibility and respect - showing up, speaking honestly, and taking action. * We learn actively and adapt rapidly. Progress comes from doing. We experiment, test, and refine, embracing iteration over perfection. * We move with urgency because patients are waiting. Speed isn't about rushing but about moving the needle every day. * We take ownership and accountability. Through ownership and accountability, we enable trust and autonomy-leaders take accountability for decisive action, and teams own outcomes together. * We are One Recursion. True cross-functional collaboration is about trust, clarity, humility, and impact. Through sharing, we can be greater than the sum of our individual capabilities. Our values underpin the employee experience at Recursion. They are the character and personality of the company demonstrated through how we communicate, support one another, spend our time, make decisions, and celebrate collectively. More About Recursion Recursion (NASDAQ: RXRX) is a clinical stage TechBio company leading the space by decoding biology to radically improve lives. Enabling its mission is the Recursion OS, a platform built across diverse technologies that continuously generate one of the world's largest proprietary biological and chemical datasets. Recursion leverages sophisticated machine-learning algorithms to distill from its dataset a collection of trillions of searchable relationships across biology and chemistry unconstrained by human bias. By commanding massive experimental scale - up to millions of wet lab experiments weekly - and massive computational scale - owning and operating one of the most powerful supercomputers in the world, Recursion is uniting technology, biology and chemistry to advance the future of medicine. Recursion is headquartered in Salt Lake City, where it is a founding member of BioHive, the Utah life sciences industry collective. Recursion also has offices in Toronto, Montréal, New York, London, Oxford area, and the San Francisco Bay area. Learn more at ****************** or connect on X (formerly Twitter) and LinkedIn. Recursion is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other characteristic protected under applicable federal, state, local, or provincial human rights legislation. Accommodations are available on request for candidates taking part in all aspects of the selection process. Recruitment & Staffing Agencies: Recursion Pharmaceuticals and its affiliate companies do not accept resumes from any source other than candidates. The submission of resumes by recruitment or staffing agencies to Recursion or its employees is strictly prohibited unless contacted directly by Recursion's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Recursion, and Recursion will not owe any referral or other fees. Our team will communicate directly with candidates who are not represented by an agent or intermediary unless otherwise agreed to prior to interviewing for the job.
    $151.8k-216.3k yearly Auto-Apply 58d ago
  • Senior Computational Biologist - Translational and Clinical Biomarkers

    Recursion 4.2company rating

    Saltaire, NY jobs

    Your work will change lives. Including your own. The Impact You'll Make As a key member of Recursion's portfolio-facing data science team, you will be at the forefront of reimagining drug discovery from first principles using Recursion's massive data and compute capabilities. You will be the primary computational lead for multiple IND and clinical stage drug development programs and will be expected to use platform and patient data to advance our most promising therapeutic candidates through clinical trials. You will be responsible for the evaluation of therapeutic hypotheses using internal and external data to identify candidate biomarkers to measure in translational studies and in phase I-II clinical trials. This is a highly collaborative role: you will partner with biologists, clinicians, platform and data engineers, and translational experts to develop and scale methods that bring patient insights and reverse translation to the forefront of our medicines portfolio. The ideal candidate has strong stakeholder management, the ability to independently scope and prioritize with ambiguous or conflicting information, and is motivated to look under every stone to do the right thing for patients. In this role, you will: Evaluate the molecular evidence for predictive and PD biomarker hypotheses in translational models and clinical samples (DNA, RNA, ct DNA, and novel exploratory modalities) Pilot novel methods for patient stratification and indication selection or expansion Deliver biological insights on therapeutic candidates and disease biology from the analysis of high dimensional (phenomics, transcriptomics, patient-derived) datasets Present data analysis to decision makers and stakeholders in a clear and compelling way that drives toward getting medicines to patients Industrialize analysis approaches to not only solve for the current project, but also accelerate future projects and scale the impact that we can have Collaborate cross-functionally with Recursion's data science, platform, ML and clinical teams to further advance Recursion's ability to leverage our own clinical data in meta-analysis, hypothesis generation, and reverse translation The Team You'll Join Our group is a bold, agile, diverse collective of computational drug discovery scientists deeply focused on the singular goal of bringing new therapeutics into the clinic at an accelerated pace. You will work extensively with scientists across the organization to advance milestones, provide insights, and drive decisions that advance Recursion's capabilities and increase our likelihood of success. Essential attributes for this role include a bold, execution-first attitude and passion for deploying rigorous science to develop life-changing medicines. We partner closely with biologists, translational scientists, and clinicians to design and execute decisional data analysis for multiple programs. We are responsible for data strategy across the portfolio and are supported by computational leadership in designing scalable and reproducible experiments that advance multiple programs at once. Our team works closely with computational biologists in other therapeutic areas (neurobiology, immunology and inflammatory diseases, etc.) as well as data scientists and engineers from our core platform teams to provide a strong network of feedback and support. The Experience You'll Need PhD in a relevant field (computational biology, systems biology, bioinformatics, cancer biology, immuno-oncology, etc.) with a very strong computational focus and 3+ years of experience in biotech or pharma industry OR MS in a relevant field and 5+ years of experience in biotech or pharma industry solving fundamental problems in oncology or drug discovery Experience with high dimensional patient biomarker data from clinical trials in oncology Strong understanding of patient genetics and druggability of disease relevant pathways Experience applying computational methods (including probabilistic, statistical, and/or machine learning techniques) to analyze and integrate complex biological and/or human clinical data in a high level programming language such as Python or R Deep expertise in the analysis and data integration of two or more ‘omics data modalities (phenomics, transcriptomics, proteomics, genomics) including experience with matched clinical and molecular patient data Exceptional data visualization skills Excellent cross-functional communication skills, including an ability to explain complex scientific concepts to a variety of audiences using a combination of plots, documents, and presentations Nice To Have: Experience with late stage drug discovery and IND submission Experience collaborating cross-functionally with biometrics, statistical sciences and clinical pharmacology departments Working Location & Compensation: This is an office-based, hybrid role in either our Salt Lake City, UT or New York City, NY offices. Employees are expected to work in the office at least 50% of the time. At Recursion, we believe that every employee should be compensated fairly. Based on the skill and level of experience required for this role, the estimated current annual base range for this role is $151,800 to $216,300 (USD). You will also be eligible for an annual bonus and equity compensation, as well as a comprehensive benefits package. #LI-EP1 The Values We Hope You Share: We act boldly with integrity. We are unconstrained in our thinking, take calculated risks, and push boundaries, but never at the expense of ethics, science, or trust. We care deeply and engage directly. Caring means holding a deep sense of responsibility and respect - showing up, speaking honestly, and taking action. We learn actively and adapt rapidly. Progress comes from doing. We experiment, test, and refine, embracing iteration over perfection. We move with urgency because patients are waiting. Speed isn't about rushing but about moving the needle every day. We take ownership and accountability. Through ownership and accountability, we enable trust and autonomy-leaders take accountability for decisive action, and teams own outcomes together. We are One Recursion. True cross-functional collaboration is about trust, clarity, humility, and impact. Through sharing, we can be greater than the sum of our individual capabilities. Our values underpin the employee experience at Recursion. They are the character and personality of the company demonstrated through how we communicate, support one another, spend our time, make decisions, and celebrate collectively. More About Recursion Recursion (NASDAQ: RXRX) is a clinical stage TechBio company leading the space by decoding biology to radically improve lives. Enabling its mission is the Recursion OS, a platform built across diverse technologies that continuously generate one of the world's largest proprietary biological and chemical datasets. Recursion leverages sophisticated machine-learning algorithms to distill from its dataset a collection of trillions of searchable relationships across biology and chemistry unconstrained by human bias. By commanding massive experimental scale - up to millions of wet lab experiments weekly - and massive computational scale - owning and operating one of the most powerful supercomputers in the world, Recursion is uniting technology, biology and chemistry to advance the future of medicine. Recursion is headquartered in Salt Lake City, where it is a founding member of BioHive, the Utah life sciences industry collective. Recursion also has offices in Toronto, Montréal, New York, London, Oxford area, and the San Francisco Bay area. Learn more at ****************** or connect on X (formerly Twitter) and LinkedIn. Recursion is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other characteristic protected under applicable federal, state, local, or provincial human rights legislation. Accommodations are available on request for candidates taking part in all aspects of the selection process. Recruitment & Staffing Agencies: Recursion Pharmaceuticals and its affiliate companies do not accept resumes from any source other than candidates. The submission of resumes by recruitment or staffing agencies to Recursion or its employees is strictly prohibited unless contacted directly by Recursion's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Recursion, and Recursion will not owe any referral or other fees. Our team will communicate directly with candidates who are not represented by an agent or intermediary unless otherwise agreed to prior to interviewing for the job.
    $151.8k-216.3k yearly Auto-Apply 57d ago
  • Senior Computational Biologist, Immunology

    Recursion 4.2company rating

    Saltaire, NY jobs

    Your work will change lives. Including your own. The Impact You'll Make As a key member of Recursion's partnership-facing data science team, you will be at the forefront of reimagining drug discovery from first principles using Recursion's massive data and compute capabilities. As senior computational biologist, you will be supporting partnership portfolio of preclinical drug programs and be responsible for designing and executing analyses to support target nomination, validation, and early programs in immunology and inflammation (I&I) diseases, translationally validates disease contexts in hit-to-lead, and accelerates in vivo work in lead optimization. You will integrate layers of Recursion platform data (phenomics, transcriptomics, proteomics, etc) to validate the link between target and disease biology and to propose targets and early programs in novel areas of immunology and inflammation. You will partner with biologists and medicinal chemists to build supporting data packets for targets from our phenomic maps, target screens, and partnered patient data sets. You will also collaborate with computational scientists from across the organization to develop, deploy, and scale novel approaches to: 1) translational validation in hit to lead, 2) mechanism-of-action identification/de-risking , and 3) build evidence for patient connectivity to match the medicines we are creating to the patients who need them. In this role, you will: Deliver biological insights on therapeutic candidates and disease biology from the analysis of high-dimensional (phenomics, transcriptomics, proteomics, patient-derived) datasets that support clinical development planning Evaluate the molecular evidence for therapeutic hypotheses and accelerate drug program progression into the clinic Present data analysis to decision makers and stakeholders in a clear and compelling way that drives toward getting medicines to patients Assess new data sources, develop and scale new analysis methods, and support key program decisions with the ultimate goal of bringing life-changing therapies to patients at unprecedented speed Industrialize analysis approaches to not only solve for the current project, but also to accelerate future projects and scale the impact that we can have Collaborate cross-functionally with Recursion's data science, biology, medicinal chemistry, and platform, teams to further advance Recursion's ability to interpret and translate large-scale data assets into therapeutic programs The Team You'll Join Our group is a bold, agile, diverse collective of computational drug discovery scientists deeply focused on the singular goal of bringing new therapeutics into the clinic at an accelerated pace. We are a computational group that spans precision oncology, I&I (immunology and inflammation), and neuroscience and focuses on advancing novel, targeted therapies for these disease areas. We partner closely with our biologists and medicinal chemists to design and execute impactful and decisional data analysis for multiple programs. We are responsible for data strategy across the portfolio and supported by computational leadership in designing scalable and reproducible experiments that serve to advance multiple programs within the portfolio. Our team collaborates extensively with computational biologists in other therapeutic areas (neurobiology, oncology, etc.) as well as data scientists and engineers from our core platform teams to provide a strong network of feedback and support. The Experience You'll Need PhD in a relevant field (computational biology, systems biology, bioinformatics, immunology/inflammation biology, immuno-oncology, etc.) with a very strong computational focus and 3+ years of experience in biotech or pharma industry OR MS in a relevant field and 5+ years of experience in biotech or pharma industry solving fundamental problems in immunology or drug discovery Experience with one or more immunology or inflammation disease areas; Experience applying computational methods (including probabilistic, statistical, and/or machine learning techniques) to analyze and integrate matched human clinical and molecular data in a high-level programming language such as Python or R Deep expertise in the analysis and data integration of one or more ‘omics data modalities (phenomics, transcriptomics, proteomics, genomics),Exceptional data visualization skills Excellent cross-functional communication skills, including an ability to explain complex scientific concepts to a variety of audiences using a combination of plots, documents, and presentations Nice To Have: Strong understanding of patient genetics and historical druggability of disease-relevant pathways, including experience working with patient data Experience in efficiently advancing drug programs from proof of concept and into clinical development Experience with immunology and inflammation clinical trial biomarker analysis Working Location & Compensation: This is an office-based, hybrid role in either our Salt Lake City, UT or New York City, NY offices. Employees are expected to work in the office at least 50% of the time. At Recursion, we believe that every employee should be compensated fairly. Based on the skill and level of experience required for this role, the estimated current annual base range for this role is $151,800 to $216,300 (USD). You will also be eligible for an annual bonus and equity compensation, as well as a comprehensive benefits package. #LI-EP1 The Values We Hope You Share: We act boldly with integrity. We are unconstrained in our thinking, take calculated risks, and push boundaries, but never at the expense of ethics, science, or trust. We care deeply and engage directly. Caring means holding a deep sense of responsibility and respect - showing up, speaking honestly, and taking action. We learn actively and adapt rapidly. Progress comes from doing. We experiment, test, and refine, embracing iteration over perfection. We move with urgency because patients are waiting. Speed isn't about rushing but about moving the needle every day. We take ownership and accountability. Through ownership and accountability, we enable trust and autonomy-leaders take accountability for decisive action, and teams own outcomes together. We are One Recursion. True cross-functional collaboration is about trust, clarity, humility, and impact. Through sharing, we can be greater than the sum of our individual capabilities. Our values underpin the employee experience at Recursion. They are the character and personality of the company demonstrated through how we communicate, support one another, spend our time, make decisions, and celebrate collectively. More About Recursion Recursion (NASDAQ: RXRX) is a clinical stage TechBio company leading the space by decoding biology to radically improve lives. Enabling its mission is the Recursion OS, a platform built across diverse technologies that continuously generate one of the world's largest proprietary biological and chemical datasets. Recursion leverages sophisticated machine-learning algorithms to distill from its dataset a collection of trillions of searchable relationships across biology and chemistry unconstrained by human bias. By commanding massive experimental scale - up to millions of wet lab experiments weekly - and massive computational scale - owning and operating one of the most powerful supercomputers in the world, Recursion is uniting technology, biology and chemistry to advance the future of medicine. Recursion is headquartered in Salt Lake City, where it is a founding member of BioHive, the Utah life sciences industry collective. Recursion also has offices in Toronto, Montréal, New York, London, Oxford area, and the San Francisco Bay area. Learn more at ****************** or connect on X (formerly Twitter) and LinkedIn. Recursion is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other characteristic protected under applicable federal, state, local, or provincial human rights legislation. Accommodations are available on request for candidates taking part in all aspects of the selection process. Recruitment & Staffing Agencies: Recursion Pharmaceuticals and its affiliate companies do not accept resumes from any source other than candidates. The submission of resumes by recruitment or staffing agencies to Recursion or its employees is strictly prohibited unless contacted directly by Recursion's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Recursion, and Recursion will not owe any referral or other fees. Our team will communicate directly with candidates who are not represented by an agent or intermediary unless otherwise agreed to prior to interviewing for the job.
    $151.8k-216.3k yearly Auto-Apply 57d ago
  • Scientist- Biologics

    Frontage Laboratories 3.9company rating

    Exton, PA jobs

    Job DescriptionScientist, Biologics Full-time Frontage Laboratories Inc. is an award winning, full-service, CRO/Contract Research Organization operating over 25 state-of-the-art laboratories across the US, Canada and China. Our core competencies include drug metabolism, pharmacokinetics/ pharmacodynamics (PK/PD), safety and toxicology, bioanalytical services, chemistry and manufacturing controls for drug development, and core laboratory services for clinical trials. Responsibilities: Primary responsibilities include, but are not limited to the following: Perform analytical and biological sample testing • Conduct method development and validation studies • Perform immunoassay techniques: (ligand binding assays, ELISA, MSD, and/or RIA applicable to Pharmacokinetic and Immunogenicity studies), with proficiency • Prepare and handle various cell lines, tissue culture media and other reagents for cell-based assays such as Neutralizing Antibody (NAb) assays • Maintenance of instruments, and address technical and instrumental issues • Assist the Principal Investigator with study conduct • Maintain study documentation • Meet regulatory compliance requirements • Maintain a safe work environment Requirements: Bachelor's degree in related scientific discipline or Bachelors degree with relevant experience • At least 2 years working in a laboratory preferred Salary and Benefits: Frontage Laboratories offers a competitive compensation and benefits package including health and dental insurance, a 401(k) plan, disability insurance, and life insurance. Frontage Laboratories Inc. is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, among other things, or status as a qualified individual with disability.
    $52k-78k yearly est. 22d ago
  • Scientist- Biologics

    Frontage Laboratories 3.9company rating

    Exton, PA jobs

    Scientist, Biologics Full-time Frontage Laboratories Inc. is an award winning, full-service, CRO/Contract Research Organization operating over 25 state-of-the-art laboratories across the US, Canada and China. Our core competencies include drug metabolism, pharmacokinetics/ pharmacodynamics (PK/PD), safety and toxicology, bioanalytical services, chemistry and manufacturing controls for drug development, and core laboratory services for clinical trials. Responsibilities: Primary responsibilities include, but are not limited to the following: Perform analytical and biological sample testing • Conduct method development and validation studies • Perform immunoassay techniques: (ligand binding assays, ELISA, MSD, and/or RIA applicable to Pharmacokinetic and Immunogenicity studies), with proficiency • Prepare and handle various cell lines, tissue culture media and other reagents for cell-based assays such as Neutralizing Antibody (NAb) assays • Maintenance of instruments, and address technical and instrumental issues • Assist the Principal Investigator with study conduct • Maintain study documentation • Meet regulatory compliance requirements • Maintain a safe work environment Requirements: Bachelor's degree in related scientific discipline or Bachelors degree with relevant experience • At least 2 years working in a laboratory preferred Salary and Benefits: Frontage Laboratories offers a competitive compensation and benefits package including health and dental insurance, a 401(k) plan, disability insurance, and life insurance. Frontage Laboratories Inc. is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, among other things, or status as a qualified individual with disability.
    $52k-78k yearly est. Auto-Apply 60d+ ago
  • Associate R&D Process Scientist

    Perrigo Company Corporate 4.9company rating

    Eau Claire, WI jobs

    At Perrigo, we are driven by our mission to Makes Lives Better Through Trusted Health and Wellness Solutions, Accessible to All. We are proud to be a Top 10 player in the European Consumer Self-Care market and the largest U.S. store brand provider of over the counter and infant formula. Dedicated to providing The Best Self-Care for Everyone, we are the people behind the brands you trust. We are Opill, Compeed, Solpadeine, NiQuitin, and many more. We Are Perrigo. We are committed to enhancing the wellbeing of our colleagues and consumers alike. We pride ourselves on fostering an inclusive, collaborative culture where each person can experience a sense of belonging. Join us on our One Perrigo journey as we evolve to win in self-care. Description Overview Perrig is currently hiring for an Associate R&D Process Scientist to lead scale-up of new infant formulas from development to full-scale production, overseeing change control, risk assessment, and factory trials while collaborating with cross-functional teams including Product Development, Pilot Plant, Operations, Quality, and Planning. Support manufacturing sites on continuous improvement opportunities in recipe and processing, driving optimization and renovation initiatives through root-cause analysis, cross-functional collaboration, and execution of cost-reduction strategies while ensuring compliance and operational excellence. Develop and implement new process capabilities via feasibility trials and continuous improvement projects to enhance efficiency, reduce costs, and improve overall product quality. Scope of the Role * Realize scale up / industrialization with Manufacturing and Quality departments. Manage change controls - review BOMs/formulations, host risk assessment meetings, setting up manufacturing forms or info, update block flow diagrams, review finished product nutrient data, recipe / process parameterization, support regulatory filings, etc * Support new process evaluations or co-man/pack capabilities or CAPEX projects for new equipments for Perrigo Nutrition business * Support manufacturing sites including root-cause analysis to address identified losses, optimize manufacturing / product quality issues, and support resolve of unscheduled downtime Experience Required * Bachelor's degree in Food or Dairy Science, Chemical or Food Engineering, Chemistry or closely related field preferred. * 1-3 years of experience in product and/or process development in the food industry or closely related is strongly preferred. * Experience in common food and dairy unit operations, infant formula manufacturing and knowledge of spray drying a plus. Benefits We believe our people are our greatest asset. Alongside competitive compensation, we offer benefits tailored to supporting you and your family, as well as career development opportunities to ensure you feel valued and supported, both professionally and personally. Find out more about Total Rewards at Perrigo. Hybrid Working Approach We love our offices and the setting they provide for in-person collaboration and celebration. But we also appreciate the opportunity to work remotely can energise you too, so we promote flexibility with the ability to work two days a week from home in many roles. We are proud to be included in the Forbes list of "America's Best Employers by State 2024". Find out more here Applicants please note: To apply to this position please click the APPLY button at the bottom of the application. (The SAVE button will only save your profile information but not submit an application for this open position.) Thank you. We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, status as a protected veteran, or other characteristics protected by law. #weareperrigo Nearest Major Market: Eau Claire
    $62k-84k yearly est. 60d+ ago
  • Immunology Principal Research Associate

    Vertex Pharmaceuticals 4.6company rating

    Seattle, WA jobs

    The discovery immunology research team is seeking a highly motivated Principal Research Associate. This is a laboratory-based role where the successful candidate will contribute directly to research efforts by designing, executing, and analyzing experiments related to immune mechanisms, target validation, and therapeutic development. The position requires strong attention to detail and ability to multitask while working in a highly collaborative environment. Key Duties and Responsibilities: Isolate, culture, and manipulate primary human immune cells and cell lines. Design and execute experiments to interrogate immune cell phenotype and function, including cell-based multicolor flow cytometry and Incucyte assays. Troubleshoot experiments and optimize protocols. Collect, analyze, and interpret experimental data while maintaining accurate and detailed laboratory records. Collaborate with scientists across discovery teams to achieve project goals. Prepare data for internal reports and presentations for internal meetings. Perform other duties as needed. Knowledge and Skills: Hands-on tissue culture experience, including the isolation and maintenance of primary human immune cells and human cell lines. Experience with nucleic acid techniques to quantify gene expression such as PCR, qPCR, and RNA sequencing. Experience with a variety of cell-based immunology assays to interrogate immune cell phenotype and function including multicolor flow cytometry and Incucyte assays. Experience measuring soluble analytes such as by ELISA, Luminex, or MSD. Critical thinking and self-reliance to solve tasks independently or ask questions. Strong organizational skills and attention to detail. Willingness and ability to work in a highly collaborative environment. Foundational knowledge of immunology and an eagerness to learn new techniques and skills. Strong analytical skills and proficiency in the following software packages: Microsoft Office, GraphPad Prism, FlowJo and Methodical Mind Analysis Software. Education and Experience: Master's degree (or equivalent degree) in biological sciences and 2+ years of relevant employment experience, or Bachelor's Degree (or equivalent degree) in biological sciences and 5+ years of relevant employment experience Pay Range: $92,900 - $139,300 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: On-Site Designated Flex Eligibility Status: In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. #LI-Onsite Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com
    $92.9k-139.3k yearly Auto-Apply 10d ago
  • Research Chemist (E&L)

    Nivagen Pharmaceuticals 3.7company rating

    Sacramento, CA jobs

    About the Company: Nivagen is a global company dedicated to enhancing lives by developing and providing cost-effective generic prescription drugs and over-the-counter products for the North American market. For over a decade, we've remained steadfast in our commitment to the core values of excellence, integrity, and respect for people. Our team of professionals collaborates tirelessly to pioneer advancements in manufacturing, distribution, and quality control, ensuring a holistic approach to healthcare. Through vertical integration of the pharmaceutical supply chain, cutting-edge technology, and unwavering dedication to excellence, we continually strive to redefine medication accessibility and affordability. We prioritize our employees' well-being by offering competitive pay, comprehensive benefits, and robust training and development opportunities. By investing in our workforce and fostering a culture of growth and support, we empower our team to drive innovation and make a positive impact in the healthcare industry. At Nivagen, our mission is clear: to make a meaningful difference in people's lives by delivering high-quality, affordable medications while upholding the highest standards of integrity and excellence. Job Location: Nivagen Pharmaceuticals Inc., Sacramento, CA 3900 Duckhorn Dr, Sacramento, CA 95834 About the Job: Title of the Position: Research Chemist (E&L) We are seeking an experienced Research Chemist (E&L) with a minimum of 3-5 years of pharmaceutical industry experience. Responsibilities: Maintain, operate, and troubleshoot LC-MS and GC-MS, GC-FID, and ICP-MS Systems. Perform extraction, analysis, and characterization of extractables and leachables from polymeric materials associated with container closure systems of pharmaceutical drug products as per USP, PQRI, ICH and other regulatory guidelines. Develop and optimize sample preparation techniques for analysis on GC-MS, LC-MS, and ICP-MS systems. Develop and validate LC-MS, GC-MS, and ICP-MS methods for finished product and raw material characterization as well as extractable/leachable testing. Unknown impurity identifications using GC-MS, LC-MS, and LC-MS/MS or other suitable techniques. Interpret complex spectral data and fragmentation patterns. Routine stability testing of API, finished product samples for assay and impurities using various instrumental techniques as suited, and prepare stability data summaries. Generate study designs, write protocols, methods, Datasheets and reports. Provide support in the critical review of analytical data, reports and protocols. Write Instrument-related SOPs and provide training on the instrument and related software. Train new recruits in the lab and support the team as needed. Participate in internal meetings and conferences. Provide support during technical transfer between R&D and QC. Whenever needed, attend SOP, Safety, and scientific trainings to remain current with cGMP regulations, safety standards, and development technologies. Preparation and review of analytical methods, method validation, and related study reports for ANDA/ NDA submissions and support, document preparation for ANDA/ NDA submissions. Any other activities as directed by the supervisor. Qualifications: Education/Experience: Bachelor's or Master's degree in Chemistry, Pharmaceutical Sciences, Biochemistry, or a related field. Knowledge, Skills, and Abilities: Familiarity with the characterization and isolation of impurities. Strong foundation in organic chemistry and structural elucidation, with expertise in small molecule pharmaceutical drug development and peptides, including computational techniques. Proficiency in using standard laboratory equipment, including pipettes, graduated cylinders, and balances. Skilled in laboratory techniques for measuring, weighing, and handling samples. Hands-on experience with HPLC (highly preferred). Knowledge of chemical handling procedures, including safety precautions and documentation such as Safety Data Sheets (SDS). Competency in Microsoft Office applications. Experience or familiarity with current Good Manufacturing Practices (cGMP) is preferred. Requirements: Must live or be willing to move to the Sacramento Metropolitan Region (Approximately 40 miles' radius) Benefits: Pay range $70,000 - $85,000 per Year Yearly bonus eligibility Benefits: Nivagen offers a wide variety of benefits and programs to support health and well-being Medical, dental and vision coverage Paid time off plan 401 (k) savings plan Additional Information: Nivagen to afford equal opportunity for employment to all individuals regardless of race, color, age, national origin, physical or mental disability, history of disability, ancestry, citizenship status, political affiliation, religion, gender, transgender, gender identity, marital status, status as a parent, sexual orientation, veteran status, genetic information or other factors prohibited by law, and to prohibit harassment o retaliation based on any of these factors.
    $70k-85k yearly Auto-Apply 44d ago
  • Associate Scientist - R&D

    Clinical Diagnostic Solutions 4.8company rating

    Plantation, FL jobs

    Clinical Diagnostic Solutions, Inc. (CDS) is a company that provides total hematology solutions for the physician office laboratory, clinic, small hospital, and veterinary office markets. At CDS, our mission is to provide the highest quality experience to our valued customers. Our employees achieve this through our cultural goals of working together through Teamwork, high Quality in the work we do, being Innovative and Courageous, always Results Oriented, and most importantly - being Customer Oriented. Under supervision, uses fundamental concepts, practices, and procedures of particular field of specialization to perform scientific, R&D tasks of some complexity requiring application and adaptation of established techniques, procedures, and criteria. Participates in new product development, optimization, validation, and transfer into production. Prioritizes work schedules to support team objectives. Job Responsibilities: Participates in method development and technical innovation within the research team and supports project timelines Performs method optimizations, validations and participates in technology transfer to production Performs routine operation, maintenance, calibration and troubleshooting of laboratory instruments such as pH, conductivity meters, osmometers, spectrnphotometers, hematology analyzers and nucroscopes Evaluates and selects methods, applies protocols and scientific techniques to accomplish study objectives Drafts and updates protocols, test methods and standard operating procedures as applicable Proactively collaborates and supports the team, communicates problems as they arise Provides solution/s to problem/ s of limited complexity, exercises judgment within defined policies to determine appropriate action Collects, analyzes and compiles data. Summarizes for interpretation and discussion Drafts statistical and narrative reports as applicable Recognizes and reports experimental variances Is able to coordinate a small project or a small component of a larger project according to set deliverables Maintains good laboratory records and documentation for experimental work and results Maintains workplace safety and environmental practices Maintains clean workplace including laboratory bench and glassware Supports the department with QC technical investigation activities as needed Works in the spirit of continuous improvement Engages in inter and intra-departmental activities/studies Performs other related duties as required or as directed. The omission of specific duties does not preclude the supervisor from assigning duties that are logically related to the position. Qualifications: Knowledge of scientific approach and methodologies. Ability to design small studies, gather, organize and analyze statistical data and generate reports Excellent oral and written communication skills Ability to investigate and analyze information and to draw conclusions Skill in the use of personal computers and related software applications such as Word/Excel/Powerpoint/Teams Knowledge of current technological developments/trends in area of expertise is desirable but not required Capable of adjusting to dynamic work environment and changing priorities Willing to take on new challenges and implement new ideas Must be Comfortable handling blood products Willing to embrace a learning environment, is open to suggestions, new ideas and innovation Ability to grasp methods fast and willingness to change course as applicable Familiar with GLP, GMP practices and capable of working in a regulated medical device company (ISO and FDA) Must have strong analytical skills Must be a team player and driven individual Must value innovation, accuracy and accountability Minimum Requirements: Bachelor's degree with 2-5 years or Associates degree with 5-8 years' experience that is directly related to the duties and responsibilities specified. EOE
    $49k-76k yearly est. 60d+ ago

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