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Research Scientist jobs at Charles River Labs

- 553 jobs
  • Support Scientist I, Bioanalytical Chemistry

    Charles River Laboratories 4.3company rating

    Research scientist job at Charles River Labs

    For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we'll help you build a career that you can feel passionate about. Job Summary We are seeking a Support Scientist I (Bioanalytical Chemistry) for our Safety Assessment Group site located in Ashland, Ohio. Basic Summary: Entry level support scientist developing skills to understand assigned department study designs. Limited or basic knowledge of data collection systems. Introduction to protocol development, regulatory compliance and internal systems utilized in the conduct of a study. Excellent verbal and written communication skills. Train to become proficient in direct communication with clients. Develop training in quantitative data analysis review. Essential Duties and Responsibilities: (The fundamental Competencies/Skills & Responsibilities of the role (products and services provided/results accomplished) include, but are not limited to, those listed: Create/customize planning tools to facilitate prioritization of daily activities. Maintain department, study, and inventory trackers in support of Project Scientist. Interact regularly with sponsors: send amendments and regulatory forms for signature, respond to sponsor-requests for information and tables, and assist with sponsor on-site visits. With guidance, write initial protocol drafts. Upon study director approval, distribute draft protocols for internal and/or sponsor review, and coordinate amendment/revision process. With guidance, facilitate signature/approval process for protocol, amendments, and other required forms. With guidance, tabulate study data and schedule data review meetings. Assist in the creation/generate special tables for sponsors as needed. With guidance, assemble report (text and data tables) for senior scientific review, QA audits, and final report compilation. Ensure that all study books are corrected appropriately, and that documentation is GLP compliant prior to submission to QA. Assist in documentation of deviations from the protocol or Standard Operating Procedures (SOP). Assist in drafting new or study specific SOPs. Efficiently perform, review, and document all study data, procedures, materials, and results in compliance with applicable regulatory standards, SOPs, and methods/protocols. Effectively complete administrative tasks such as filing and placing orders as needed. Develop effective communication skills through informal discussions with peers, supervisor, team and Sponsor/SDs. Develop critical thinking, troubleshooting and time management skills aligned with needs of operational areas. Perform all other related duties as assigned. The pay range for this position is $22-24 USD per hour. Please note that starting salaries vary based on factors including, but not limited to, experience, skills, education, certifications, and location. *THIS IS A HYBRID ROLE* Job Qualifications (Knowledge, Experience, Skills and Abilities required to accomplish the essential functions) include but are not limited to: Education: High School diploma or General Education Degree (G.E.D.) preferred. Associate's degree (A.A./A.S.) or equivalent from two-year college recommended. Bachelor's degree (B.A./B.S.) or equivalent in related discipline strongly recommended. Experience: Zero to two years related experience in biology, chemistry/pharmacy, or similar lab environment. GLP experience preferred. An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above. Certification/Licensure: None. Other: This position requires analytical thinking skills and a good understanding of scientific processes. Strong organizational skills and attention to detail required, as are computer skills including MS Office software and database management. Knowledge of GLP regulations and understanding of routine study design and protocols. Comments: This position requires overtime, weekend, holiday, and/or after hours shift coverage, as needed. About Safety Assessment Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market. Each year approximately 300 investigational new drug (IND) programs are conducted in our Safety Assessment facilities. About Charles River Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients' clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market. With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client's unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. At Charles River, we are passionate about our role in improving the quality of people's lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly worked on 80% of the drugs approved by the U.S. Food and Drug Administration (FDA) in the past five years. We're committed to providing benefits that elevate your quality of life. Based on your position these may include: bonus/incentives based on performance, 401K, paid time off, stock purchase program, Health and wellness coverage, employee and family wellbeing support programs, and work life balance flexibility. Equal Employment Opportunity Charles River Laboratories is an Equal Opportunity Employer - all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status. It is unlawful in some states (including Massachusetts) to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitment_**********. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications. For more information, please visit ***************
    $22-24 hourly Easy Apply 47d ago
  • Scientist - Downstream Process Development

    Kelly 4.1company rating

    Gaithersburg, MD jobs

    Kelly Government Solutions is seeking a Scientist - Downstream Process Development to work on-site with the Vaccine Production Program at the National Institute of Allergy and Infectious Diseases (NIAID)/National Institutes of Health (NIH) in Gaithersburg, MD. KEY TASKS/SERVICES (1) Support the Purification group of the Vaccine Production Program (VPP) Labs of the Vaccine Research Center (VRC). (2) Develop downstream (purification) processes, under the supervision of a project lead scientist, for recombinant proteins, virus vaccines, and virus-like particles (VLP) that may be used as clinical vaccine candidates. (3) Serve as a functional lead in chromatography process development unit operations. (4) Provide critical process step assessment and experimental design to define optimal process parameters for chromatography unit operations. (5) Train team members in large-scale unit operation such as AxiChrom column packing and Pilot-scale chromatography execution. (6) Work independently and collaboratively within the purification group to design, develop and optimize chromatography and filtration step unit operations to support process development of clinical trial vaccine candidates and mAb products. (7) Purify research-phase recombinant proteins, virus vaccines and/or virus-like particles in support of other groups at the VRC. (8) Work to prepare necessary materials (buffers, packed columns, etc.) in support of downstream process activities. (9) Perform protein/small molecule conjugation experiments to support method development or conjugate-based vaccine candidates. (10) Support technology transfer of processes to VRC Pilot Plant for manufacture of clinical products including authoring process descriptions, reports, and on-floor support. (11) Author training documents, process documents and summaries, instrument SOPs, technical reports, protocols, and other supporting documentation. KEY REQUIREMENTS (1) Ph.D. in Bioengineering, Chemical Engineering, Biochemistry, or related scientific discipline (2) Extensive experience in recombinant protein purification development for GMP clinical-phase products (3) Familiarity with monoclonal antibody and multi-specific antibodies, recombinant protein vaccine and nanoparticles; mRNA and mRNA/LNP vaccines.
    $68k-93k yearly est. 1d ago
  • Scientist I, Disease Mechanism Research

    Astellas Pharma 4.9company rating

    South San Francisco, CA jobs

    Do you want to be part of an inclusive team that works to develop innovative therapies for patients? Every day, we are driven to develop and deliver innovative and effective new medicines to patients and physicians. If you want to be part of this exciting work, you belong at Astellas! Astellas Pharma Inc. is a pharmaceutical company conducting business in more than 70 countries around the world. We are committed to turning innovative science into medical solutions that bring value and hope to patients and their families. Keeping our focus on addressing unmet medical needs and conducting our business with ethics and integrity enables us to improve the health of people throughout the world. For more information on Astellas, please visit our website at ***************** Purpose: The Disease Mechanism Research team is seeking a candidate with experience in the drug discovery that demonstrated ability to conceive, lead and execute research programs in oncology. The candidate should have exceptional analytical skills enabling them to interpret and communicate intricate scientific insights effectively. A successful candidate will contribute to a deeper understanding of mechanisms of therapeutic resistance in focused cancer indications and support the enabling of Astellas pipeline in oncology. Essential Job Responsibilities: Responsible for design and developing novel models of cancer recapitulating therapeutic resistance across modalities Drive execution, and analysis of non-clinical studies in oncology necessary to validate novel therapeutic concepts and modalities including T-cell engagers and ADC Provide scientific and technical expertise to delivery deeper understanding of mechanisms of action of emerging drugs in oncology Create an organoid biobank derived from human patient samples for evaluation of molecules in the Astellas pipeline using more physiologically relevant models Seek and apply innovative approaches to understand tumor resistance to targeted and IO therapies Act as an oncology expert in cross functional team Support multiple projects simultaneously and work cross-functionally with colleagues in Disease Mechanism Research group and across Astellas' Cancer Research team.
    $95k-157k yearly est. 2d ago
  • Scientist I, Disease Mechanism Research

    Astellas Pharma, Inc. 4.9company rating

    South San Francisco, CA jobs

    Do you want to be part of an inclusive team that works to develop innovative therapies for patients? Every day, we are driven to develop and deliver innovative and effective new medicines to patients and physicians. If you want to be part of this exciting work, you belong at Astellas! Astellas Pharma Inc. is a pharmaceutical company conducting business in more than 70 countries around the world. We are committed to turning innovative science into medical solutions that bring value and hope to patients and their families. Keeping our focus on addressing unmet medical needs and conducting our business with ethics and integrity enables us to improve the health of people throughout the world. For more information on Astellas, please visit our website at ***************** Purpose: The Disease Mechanism Research team is seeking a candidate with experience in the drug discovery that demonstrated ability to conceive, lead and execute research programs in oncology. The candidate should have exceptional analytical skills enabling them to interpret and communicate intricate scientific insights effectively. A successful candidate will contribute to a deeper understanding of mechanisms of therapeutic resistance in focused cancer indications and support the enabling of Astellas pipeline in oncology. Essential Job Responsibilities: * Responsible for design and developing novel models of cancer recapitulating therapeutic resistance across modalities * Drive execution, and analysis of non-clinical studies in oncology necessary to validate novel therapeutic concepts and modalities including T-cell engagers and ADC * Provide scientific and technical expertise to delivery deeper understanding of mechanisms of action of emerging drugs in oncology * Create an organoid biobank derived from human patient samples for evaluation of molecules in the Astellas pipeline using more physiologically relevant models * Seek and apply innovative approaches to understand tumor resistance to targeted and IO therapies * Act as an oncology expert in cross functional team * Support multiple projects simultaneously and work cross-functionally with colleagues in Disease Mechanism Research group and across Astellas' Cancer Research team.
    $95k-157k yearly est. 11d ago
  • Scientist I, Disease Mechanism Research

    Astellas Pharma 4.9company rating

    South San Francisco, CA jobs

    Do you want to be part of an inclusive team that works to develop innovative therapies for patients? Every day, we are driven to develop and deliver innovative and effective new medicines to patients and physicians. If you want to be part of this exciting work, you belong at Astellas! Astellas Pharma Inc. is a pharmaceutical company conducting business in more than 70 countries around the world. We are committed to turning innovative science into medical solutions that bring value and hope to patients and their families. Keeping our focus on addressing unmet medical needs and conducting our business with ethics and integrity enables us to improve the health of people throughout the world. For more information on Astellas, please visit our website at **************** . **Purpose:** The Disease Mechanism Research team is seeking a candidate with experience in the drug discovery that demonstrated ability to conceive, lead and execute research programs in oncology. The candidate should have exceptional analytical skills enabling them to interpret and communicate intricate scientific insights effectively. A successful candidate will contribute to a deeper understanding of mechanisms of therapeutic resistance in focused cancer indications and support the enabling of Astellas pipeline in oncology. **Essential Job Responsibilities:** + Responsible for design and developing novel models of cancer recapitulating therapeutic resistance across modalities + Drive execution, and analysis of non-clinical studies in oncology necessary to validate novel therapeutic concepts and modalities including T-cell engagers and ADC + Provide scientific and technical expertise to delivery deeper understanding of mechanisms of action of emerging drugs in oncology + Create an organoid biobank derived from human patient samples for evaluation of molecules in the Astellas pipeline using more physiologically relevant models + Seek and apply innovative approaches to understand tumor resistance to targeted and IO therapies + Act as an oncology expert in cross functional team + Support multiple projects simultaneously and work cross-functionally with colleagues in Disease Mechanism Research group and across Astellas' Cancer Research team. **Qualifications Required:** + PhD. or MS in Oncology, Biochemistry, Molecular Biology, Immuno-Oncology, or a related field, with a strong background in cancer model development with +3 years for PhD and +8 year for MS of relevant experience. + Proven expertise in solid tumor indications + Exceptional understanding of mechanisms of cancer maintenance and key signaling pathways in the disease with the particular focus on prostate and lung cancer + Experience with advanced molecular biology techniques including CRISPR/Cas9 gene editing, flow cytometry, and cell culture of both, primary tumour cells and established tumour cell lines. + Excellent problem-solving skills and the ability to design and execute hypothesis-driven research projects independently. + Effective communication skills, with the ability to present complex scientific data clearly to both technical and non-technical audiences. + Strong collaborative capabilities, with experience working in multidisciplinary teams to achieve common research goals. + Strong organizational skills with the ability to manage multiple projects and meet deadlines effectively. + Solid data science and analytical skills, as well as excellent written and oral communication in English **Preferred:** + Strong track record of research productivity as evidenced by high-quality, impactful publications. + Knowledge of prostate and/or lung cancer biology and treatment paradigm + Experience working with small molecules and biologics + Proficiency in evaluating cell signaling + Attention to details with excellent organizational and record keeping skills **Working Environment:** This position is based in South San Francisco (Wester Coast Innovation Center) and will require on-site work. **Salary Range:** $91,000 - $143,000 (Final compensation will be determined based on a variety of factors, including but not limited to skills, experience, and organizational equity considerations). **Benefits:** + Medical, Dental and Vision Insurance + Generous Paid Time Off options, including Vacation and Sick time, plus national holidays including year-end shut down + 401(k) match and annual company contribution + Company paid life insurance + Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions + Long Term Incentive Plan for eligible positions + Company-paid fleet vehicle for eligible positions + Referral bonus program **\#LI-TR1** Category Cancer Biology Astellas is committed to equality of opportunity in all aspects of employment. EOE including Disability/Protected Veterans
    $91k-143k yearly 11d ago
  • Research Scientist - Bioanalytical dept

    Qps Holdings, LLC 4.5company rating

    Newark, DE jobs

    Do you want to be part of an organization that is making a difference in the lives of millions of people worldwide? If so, we want to hear from you! QPS, LLC has an opening for a Research Scientist in our Bioanalytical (GBA) department. GBA is comprised of three laboratory operation unit: Small Molecules, Proteins, and Oligonucleotides, and each unit has their own Method Development/Method Validation/Sample Analysis (MD/MV/SA) group. In this role, you will play a pivotal part in QPS' continued expansion of our bioanalytical capabilities to support drug development of small molecules, antibody drug conjugate, protein, and genetic medicines.
    $77k-115k yearly est. Auto-Apply 27d ago
  • Research Scientist

    Pacific Institute for Research and Evaluation 4.2company rating

    Berkeley, CA jobs

    Requirements An advanced degree (e.g., M.D., Ph.D., J.D.) or equivalent experience At least five years experience in a relevant professional research environment. Demonstrated ability to independently develop a research program. An established record of obtaining peer-reviewed funding alone or in collaboration with others. The ability to work for any US employer.
    $99k-165k yearly est. 60d+ ago
  • Molecular Markers Lab Research Scientist

    Advanta 4.5company rating

    College Station, TX jobs

    Advanta is a global seed business adapting to rapidly increasing food insecurity and climate change by providing farmers with innovation and new technologies. As part of UPL Group, Advanta aims to deliver high quality seeds with excellent agronomic practices and crop protection solutions. Advanta operates in over 80 countries under global brands of Advanta, Alta and Pacific Seeds. Advanta holds a leadership position in tropical and sub-tropical geographies in corn, grain and forage sorghum, sunflower, canola, rice, and a variety of vegetables. With over 60 years' experience in plant genetics, Advanta provides seeds technology that ensures crop performance and farmers prosperity. We are seeking a motivated individual who desires to be part of a dynamic, fast growing and diverse team in a high throughput genotyping and molecular lab to support the crop breeding program at Advanta Seeds. Responsibilities: Develop Adventitious Presence testing process using Digital Droplet PCR (dd PCR) technology. Continuous improvement of existing laboratory processes like DNA extraction and end-point genotyping using high-throughput robotic platforms. Operate and maintain complex laboratory instrumentation. Accurately and timely document the experiments and results. Effective and timely communication with other Scientists/Managers pertaining to project updates. Ensure workplace safety by adhering to the safety SOP. Train other lab technicians/Research Associates as needed. Required and Desired Skills: A PhD degree in biology, genetics, plant science, crop science, biotechnology or other related fields. Experience with plant DNA extraction protocols, Digital Droplet and End-point PCR, and other routine molecular lab skills are a must. Experience and knowledge in molecular marker development (SNP's) high-throughput genotyping, and lab automation are required. Understanding plant molecular breeding applications is desired Strong attention to details and the ability to understand and follow detailed written instructions and established SOPs. Proactive, self-motivated and self-driven person with high accountability. Team players with excellent interpersonal and communication skills. Demonstrated ability to track, prioritize and manage multiple tasks to meet the timeline. Industry experience is desired. Cultural sensitivity We are one team, for maximum impact. One team with shared goals. We all play for the team and no one plays against the team. We have a laser-like focus on what our customers need and want, on anticipating their future needs and on how we can create innovative solutions and experiences for them. #AdvantaJobs
    $42k-66k yearly est. 60d+ ago
  • Scientist- Biologics

    Frontage Lab 3.9company rating

    Exton, PA jobs

    Scientist, Biologics Full-time Frontage Laboratories Inc. is an award winning, full-service, CRO/Contract Research Organization operating over 25 state-of-the-art laboratories across the US, Canada and China. Our core competencies include drug metabolism, pharmacokinetics/ pharmacodynamics (PK/PD), safety and toxicology, bioanalytical services, chemistry and manufacturing controls for drug development, and core laboratory services for clinical trials. Responsibilities: Primary responsibilities include, but are not limited to the following: * Perform analytical and biological sample testing * Conduct method development and validation studies * Perform immunoassay techniques: (ligand binding assays, ELISA, MSD, and/or RIA applicable to Pharmacokinetic and Immunogenicity studies), with proficiency * Prepare and handle various cell lines, tissue culture media and other reagents for cell-based assays such as Neutralizing Antibody (NAb) assays * Maintenance of instruments, and address technical and instrumental issues * Assist the Principal Investigator with study conduct * Maintain study documentation * Meet regulatory compliance requirements * Maintain a safe work environment Requirements: * Bachelor's degree in related scientific discipline or Bachelors degree with relevant experience * At least 2 years working in a laboratory preferred Salary and Benefits: Frontage Laboratories offers a competitive compensation and benefits package including health and dental insurance, a 401(k) plan, disability insurance, and life insurance. Frontage Laboratories Inc. is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, among other things, or status as a qualified individual with disability. *
    $52k-78k yearly est. 60d+ ago
  • Scientist- Biologics

    Frontage Laboratories 3.9company rating

    Exton, PA jobs

    Scientist, Biologics Full-time Frontage Laboratories Inc. is an award winning, full-service, CRO/Contract Research Organization operating over 25 state-of-the-art laboratories across the US, Canada and China. Our core competencies include drug metabolism, pharmacokinetics/ pharmacodynamics (PK/PD), safety and toxicology, bioanalytical services, chemistry and manufacturing controls for drug development, and core laboratory services for clinical trials. Responsibilities: Primary responsibilities include, but are not limited to the following: Perform analytical and biological sample testing • Conduct method development and validation studies • Perform immunoassay techniques: (ligand binding assays, ELISA, MSD, and/or RIA applicable to Pharmacokinetic and Immunogenicity studies), with proficiency • Prepare and handle various cell lines, tissue culture media and other reagents for cell-based assays such as Neutralizing Antibody (NAb) assays • Maintenance of instruments, and address technical and instrumental issues • Assist the Principal Investigator with study conduct • Maintain study documentation • Meet regulatory compliance requirements • Maintain a safe work environment Requirements: Bachelor's degree in related scientific discipline or Bachelors degree with relevant experience • At least 2 years working in a laboratory preferred Salary and Benefits: Frontage Laboratories offers a competitive compensation and benefits package including health and dental insurance, a 401(k) plan, disability insurance, and life insurance. Frontage Laboratories Inc. is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, among other things, or status as a qualified individual with disability.
    $52k-78k yearly est. Auto-Apply 60d+ ago
  • Scientist- Biologics

    Frontage Laboratories 3.9company rating

    Exton, PA jobs

    Job DescriptionScientist, Biologics Full-time Frontage Laboratories Inc. is an award winning, full-service, CRO/Contract Research Organization operating over 25 state-of-the-art laboratories across the US, Canada and China. Our core competencies include drug metabolism, pharmacokinetics/ pharmacodynamics (PK/PD), safety and toxicology, bioanalytical services, chemistry and manufacturing controls for drug development, and core laboratory services for clinical trials. Responsibilities: Primary responsibilities include, but are not limited to the following: Perform analytical and biological sample testing • Conduct method development and validation studies • Perform immunoassay techniques: (ligand binding assays, ELISA, MSD, and/or RIA applicable to Pharmacokinetic and Immunogenicity studies), with proficiency • Prepare and handle various cell lines, tissue culture media and other reagents for cell-based assays such as Neutralizing Antibody (NAb) assays • Maintenance of instruments, and address technical and instrumental issues • Assist the Principal Investigator with study conduct • Maintain study documentation • Meet regulatory compliance requirements • Maintain a safe work environment Requirements: Bachelor's degree in related scientific discipline or Bachelors degree with relevant experience • At least 2 years working in a laboratory preferred Salary and Benefits: Frontage Laboratories offers a competitive compensation and benefits package including health and dental insurance, a 401(k) plan, disability insurance, and life insurance. Frontage Laboratories Inc. is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, among other things, or status as a qualified individual with disability.
    $52k-78k yearly est. 22d ago
  • Pharmacology Research Scientist

    Vertex Pharmaceuticals 4.6company rating

    Boston, MA jobs

    We are seeking a talented, self-motivated and collaborative in-vivo pharmacologist to join the integrated pharmacology team supporting late-stage drug discovery. The ideal candidate will have a strong foundation in pharmacology, work with a high degree of independence and be adept at conceptually designing, executing and interpreting in vivo/ex vivo experiments to establish therapeutic proof-of-concept across diverse disease areas. Key Duties and Responsibilities: Designs and conducts elaborate, conceptually connected, multi-component in vivo/ex vivo experiments to demonstrate proof-of-concept in preclinical disease models including pharmacokinetic, pharmacodynamic and efficacy relationships. Perform advanced and/or complex experimental assay development and troubleshooting. Collates and interprets complex data systematically and synthesizes results into a cohesive body of conclusions or recommendations to guide Project decisions and new research activities. Exercises solid judgment to prioritize studies, considering feasibility and Project impact. Scours relevant scientific literature and routinely incorporates new insights into research activities. Identifies, prioritizes and introduces relevant emerging technologies in their field of expertise to advance the existing technology platforms and create/maintain a competitive advantage. Explores the feasibility of applying new scientific principles/concepts or implements and validates novel experimental approaches and technologies to achieve project goals. Contributes significantly to patent and/or publication preparation. Independently prepares study presentations and presents experimental conclusions at internal Group/Department or Project Team research meetings. Performs other duties as assigned. Knowledge and Skills: Designs and executes complex, well controlled, challenging experiments that measure the action of compounds on in vivo/ex vivo disease biology assays. Maintains a broad working knowledge of fundamental pharmacology principles. Demonstrates astute understanding of his/her own discipline and the relevant literature. Maintains a high level of knowledge related to current developments in the scientific Project field. Displays proven productivity and experimental creativity, and effective dissemination of ideas. Demonstrates effective, self-sufficient communication skills, especially in peer-directed presentations. Demonstrates awareness of other Project-related disciplines and an understanding of general concepts and some experimental detail within those areas. Must be proficient in rodent handling, dosing (IV, PO, IP, SC), blood collection (tail nick, submandibular, cardiac puncture) and tissue harvesting. Demonstrate experience developing, executing and troubleshooting assays across a wide array of in vivo and molecular techniques (i.e. ELISA, qPCR, Western and flow cytometry). Ability to rapidly learn and master new techniques and technologies. Essential qualities include: integrity, flexibility, adaptability, organization and multi-tasking skills, excellent record keeping and the ability to function both independently and effectively as part of an interactive and cross-functional team. Education and Experience: Bachelor's degree in pharmacology or related biological sciences Typically requires a PhD and 0-3 years of experience or, Typically requires a Masters degree and 3 years of experience or, Typically requires a Bachelors degree and 6 years of experience #LI-KM4 #LI-Onsite Pay Range: $105,600 - $158,400 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: On-Site Designated Flex Eligibility Status: In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. #LI-Onsite Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com
    $105.6k-158.4k yearly Auto-Apply 60d+ ago
  • Biomedical Research Scientist

    Revance 4.2company rating

    Dallas, TX jobs

    The Biomedical Research Scientist conducts research, develops, designs, and executes biomedical research studies, and assesses feasibility, scientific validity, and efficacy of selected Revance innovation projects, emerging technology, and current Revance products. The Biomedical Research Scientist conducts and analyzes study results regarding instrumental or other laboratory-based and/or clinical findings, as well as makes critical assessments to the direction of research work for areas within Biomedical Innovation. This role is responsible for new technology evaluation in the areas of skin aesthetics, therapeutics (OTC), and skincare (non-drug) areas. These include methodologies using biochemical, cellular, tissue construct, ex-vivo skin and human subject donor for dermatological evaluation. Specific details to these endpoints are considered proprietary. This role also has responsibility for the evaluation of current (Revance and competitive) marketed products for reproducibility, performance, and where appropriate, product claims. Often these values are compared to historical control values to determine lot-to-lot acceptance, quality standards, competitive advantage, or product troubleshooting. These tests include the evaluation of new techniques to increase product performance or troubleshooting product failures. The Biomedical department conducts a wide range of external research studies and collaborations for the development and evaluation of technologies using genomic, proteomic, lipidomic, metabolic endpoints, in vivo , in vitro , and biome-based areas. Reporting to: VP, Clinical Development & Biomedical Innovation Location: Dallas, TX - onsite Responsibilities/Essential Duties: Manage the inventory of Biomedical Innovation Lab equipment and lab supplies related to the various inhouse studies. Attend meetings, events and seminars in order to detail, discuss and promoted various Biomedical Innovation studies. Collect specimens and input data and information into an electronic system. Complete visits with study subjects, and schedule follow-ups for samples or evaluation. Collaborate closely with other Revance research (Bioscience department) and Clinical staff in scheduling future appointments or shipments for biological sourced material to be evaluated in Biomedical assays. Act as Lead Scientist on research, study designs, protocol development, data analysis, interpretation and presentation. This includes both internal and external studies as described for the areas of research for the department. Create presentations related to study progress with are presented to the Scientific Affairs research team and upper management. Basic Qualifications: Bachelor's degree & 7-10 years' directly related experience; OR Master's degree & 3-5 years' directly related experience; OR PhD and 2+ years' directly related experience. Preferred Qualifications: PhD in Biochemistry, Biology, Biomechanical Engineering, or Molecular Biology. 2-4 years' experience in medical device or pharmaceuticals. Company Summary: Revance is a fast-growing global aesthetics and skincare company focused on providing innovative aesthetics and market-leading skincare offerings throughout every stage of life. With a differentiated portfolio of products spanning 60 countries, Revance meets the evolving needs of patients and consumers worldwide through continued innovation and commercialization of new products and treatments. What Revance invests in you: Competitive Compensation including base salary and annual performance bonus. Flexible PTO, holidays, and parental leave. Generous healthcare benefits, HSA match, 401k match, employer paid life and disability insurance, pet insurance, wellness discounts and much more! This section of the is required by the American with Disability Act (ADA). The ADA requires that job descriptions reflect the physical and mental demands required to effectively perform the essential duties of the job. The ADA prohibits employers from discriminating against a “qualified individual with a disability” in all aspects of the employment relationship. A “qualified individual with a disability” is “an individual who meets the education, experience, skill, and other job-related requirements of a position held or desired, and who, with reasonable accommodation, can perform the essential functions of a specified job.” Revance is an Equal Opportunity employer. All qualified applicants will receive consideration for employment based on merit, without regard to race, color, religion, sex, national origin, disability, protected Veteran Status, or any other characteristic protected by applicable federal, state, or local law.
    $47k-66k yearly est. Auto-Apply 17d ago
  • Senior Computational Biologist - Translational and Clinical Biomarkers

    Recursion Pharmaceuticals 4.2company rating

    New York, NY jobs

    Your work will change lives. Including your own. Please note: Our offices will be closed for our annual winter break from December 22, 2025, to January 2, 2026. Our response to your application will be delayed. The Impact You'll Make As a key member of Recursion's portfolio-facing data science team, you will be at the forefront of reimagining drug discovery from first principles using Recursion's massive data and compute capabilities. You will be the primary computational lead for multiple IND and clinical stage drug development programs and will be expected to use platform and patient data to advance our most promising therapeutic candidates through clinical trials. You will be responsible for the evaluation of therapeutic hypotheses using internal and external data to identify candidate biomarkers to measure in translational studies and in phase I-II clinical trials. This is a highly collaborative role: you will partner with biologists, clinicians, platform and data engineers, and translational experts to develop and scale methods that bring patient insights and reverse translation to the forefront of our medicines portfolio. The ideal candidate has strong stakeholder management, the ability to independently scope and prioritize with ambiguous or conflicting information, and is motivated to look under every stone to do the right thing for patients. In this role, you will: * Evaluate the molecular evidence for predictive and PD biomarker hypotheses in translational models and clinical samples (DNA, RNA, ct DNA, and novel exploratory modalities) * Pilot novel methods for patient stratification and indication selection or expansion * Deliver biological insights on therapeutic candidates and disease biology from the analysis of high dimensional (phenomics, transcriptomics, patient-derived) datasets * Present data analysis to decision makers and stakeholders in a clear and compelling way that drives toward getting medicines to patients * Industrialize analysis approaches to not only solve for the current project, but also accelerate future projects and scale the impact that we can have * Collaborate cross-functionally with Recursion's data science, platform, ML and clinical teams to further advance Recursion's ability to leverage our own clinical data in meta-analysis, hypothesis generation, and reverse translation The Team You'll Join Our group is a bold, agile, diverse collective of computational drug discovery scientists deeply focused on the singular goal of bringing new therapeutics into the clinic at an accelerated pace. You will work extensively with scientists across the organization to advance milestones, provide insights, and drive decisions that advance Recursion's capabilities and increase our likelihood of success. Essential attributes for this role include a bold, execution-first attitude and passion for deploying rigorous science to develop life-changing medicines. We partner closely with biologists, translational scientists, and clinicians to design and execute decisional data analysis for multiple programs. We are responsible for data strategy across the portfolio and are supported by computational leadership in designing scalable and reproducible experiments that advance multiple programs at once. Our team works closely with computational biologists in other therapeutic areas (neurobiology, immunology and inflammatory diseases, etc.) as well as data scientists and engineers from our core platform teams to provide a strong network of feedback and support. The Experience You'll Need * PhD in a relevant field (computational biology, systems biology, bioinformatics, cancer biology, immuno-oncology, etc.) with a very strong computational focus and 3+ years of experience in biotech or pharma industry OR MS in a relevant field and 5+ years of experience in biotech or pharma industry solving fundamental problems in oncology or drug discovery * Experience with high dimensional patient biomarker data from clinical trials in oncology * Strong understanding of patient genetics and druggability of disease relevant pathways * Experience applying computational methods (including probabilistic, statistical, and/or machine learning techniques) to analyze and integrate complex biological and/or human clinical data in a high level programming language such as Python or R * Deep expertise in the analysis and data integration of two or more 'omics data modalities (phenomics, transcriptomics, proteomics, genomics) including experience with matched clinical and molecular patient data * Exceptional data visualization skills * Excellent cross-functional communication skills, including an ability to explain complex scientific concepts to a variety of audiences using a combination of plots, documents, and presentations Nice To Have: * Experience with late stage drug discovery and IND submission * Experience collaborating cross-functionally with biometrics, statistical sciences and clinical pharmacology departments Working Location & Compensation: This is an office-based, hybrid role in either our Salt Lake City, UT or New York City, NY offices. Employees are expected to work in the office at least 50% of the time. At Recursion, we believe that every employee should be compensated fairly. Based on the skill and level of experience required for this role, the estimated current annual base range for this role is $151,800 to $216,300 (USD). You will also be eligible for an annual bonus and equity compensation, as well as a comprehensive benefits package. #LI-EP1 The Values We Hope You Share: * We act boldly with integrity. We are unconstrained in our thinking, take calculated risks, and push boundaries, but never at the expense of ethics, science, or trust. * We care deeply and engage directly. Caring means holding a deep sense of responsibility and respect - showing up, speaking honestly, and taking action. * We learn actively and adapt rapidly. Progress comes from doing. We experiment, test, and refine, embracing iteration over perfection. * We move with urgency because patients are waiting. Speed isn't about rushing but about moving the needle every day. * We take ownership and accountability. Through ownership and accountability, we enable trust and autonomy-leaders take accountability for decisive action, and teams own outcomes together. * We are One Recursion. True cross-functional collaboration is about trust, clarity, humility, and impact. Through sharing, we can be greater than the sum of our individual capabilities. Our values underpin the employee experience at Recursion. They are the character and personality of the company demonstrated through how we communicate, support one another, spend our time, make decisions, and celebrate collectively. More About Recursion Recursion (NASDAQ: RXRX) is a clinical stage TechBio company leading the space by decoding biology to radically improve lives. Enabling its mission is the Recursion OS, a platform built across diverse technologies that continuously generate one of the world's largest proprietary biological and chemical datasets. Recursion leverages sophisticated machine-learning algorithms to distill from its dataset a collection of trillions of searchable relationships across biology and chemistry unconstrained by human bias. By commanding massive experimental scale - up to millions of wet lab experiments weekly - and massive computational scale - owning and operating one of the most powerful supercomputers in the world, Recursion is uniting technology, biology and chemistry to advance the future of medicine. Recursion is headquartered in Salt Lake City, where it is a founding member of BioHive, the Utah life sciences industry collective. Recursion also has offices in Toronto, Montréal, New York, London, Oxford area, and the San Francisco Bay area. Learn more at ****************** or connect on X (formerly Twitter) and LinkedIn. Recursion is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other characteristic protected under applicable federal, state, local, or provincial human rights legislation. Accommodations are available on request for candidates taking part in all aspects of the selection process. Recruitment & Staffing Agencies: Recursion Pharmaceuticals and its affiliate companies do not accept resumes from any source other than candidates. The submission of resumes by recruitment or staffing agencies to Recursion or its employees is strictly prohibited unless contacted directly by Recursion's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Recursion, and Recursion will not owe any referral or other fees. Our team will communicate directly with candidates who are not represented by an agent or intermediary unless otherwise agreed to prior to interviewing for the job.
    $151.8k-216.3k yearly Auto-Apply 27d ago
  • Senior Computational Biologist, Immunology

    Recursion Pharmaceuticals 4.2company rating

    New York, NY jobs

    Your work will change lives. Including your own. Please note: Our offices will be closed for our annual winter break from December 22, 2025, to January 2, 2026. Our response to your application will be delayed. The Impact You'll Make As a key member of Recursion's partnership-facing data science team, you will be at the forefront of reimagining drug discovery from first principles using Recursion's massive data and compute capabilities. As senior computational biologist, you will be supporting partnership portfolio of preclinical drug programs and be responsible for designing and executing analyses to support target nomination, validation, and early programs in immunology and inflammation (I&I) diseases, translationally validates disease contexts in hit-to-lead, and accelerates in vivo work in lead optimization. You will integrate layers of Recursion platform data (phenomics, transcriptomics, proteomics, etc) to validate the link between target and disease biology and to propose targets and early programs in novel areas of immunology and inflammation. You will partner with biologists and medicinal chemists to build supporting data packets for targets from our phenomic maps, target screens, and partnered patient data sets. You will also collaborate with computational scientists from across the organization to develop, deploy, and scale novel approaches to: 1) translational validation in hit to lead, 2) mechanism-of-action identification/de-risking , and 3) build evidence for patient connectivity to match the medicines we are creating to the patients who need them. In this role, you will: * Deliver biological insights on therapeutic candidates and disease biology from the analysis of high-dimensional (phenomics, transcriptomics, proteomics, patient-derived) datasets that support clinical development planning * Evaluate the molecular evidence for therapeutic hypotheses and accelerate drug program progression into the clinic * Present data analysis to decision makers and stakeholders in a clear and compelling way that drives toward getting medicines to patients * Assess new data sources, develop and scale new analysis methods, and support key program decisions with the ultimate goal of bringing life-changing therapies to patients at unprecedented speed * Industrialize analysis approaches to not only solve for the current project, but also to accelerate future projects and scale the impact that we can have * Collaborate cross-functionally with Recursion's data science, biology, medicinal chemistry, and platform, teams to further advance Recursion's ability to interpret and translate large-scale data assets into therapeutic programs The Team You'll Join Our group is a bold, agile, diverse collective of computational drug discovery scientists deeply focused on the singular goal of bringing new therapeutics into the clinic at an accelerated pace. We are a computational group that spans precision oncology, I&I (immunology and inflammation), and neuroscience and focuses on advancing novel, targeted therapies for these disease areas. We partner closely with our biologists and medicinal chemists to design and execute impactful and decisional data analysis for multiple programs. We are responsible for data strategy across the portfolio and supported by computational leadership in designing scalable and reproducible experiments that serve to advance multiple programs within the portfolio. Our team collaborates extensively with computational biologists in other therapeutic areas (neurobiology, oncology, etc.) as well as data scientists and engineers from our core platform teams to provide a strong network of feedback and support. The Experience You'll Need * PhD in a relevant field (computational biology, systems biology, bioinformatics, immunology/inflammation biology, immuno-oncology, etc.) with a very strong computational focus and 3+ years of experience in biotech or pharma industry OR MS in a relevant field and 5+ years of experience in biotech or pharma industry solving fundamental problems in immunology or drug discovery * Experience with one or more immunology or inflammation disease areas; * Experience applying computational methods (including probabilistic, statistical, and/or machine learning techniques) to analyze and integrate matched human clinical and molecular data in a high-level programming language such as Python or R * Deep expertise in the analysis and data integration of one or more 'omics data modalities (phenomics, transcriptomics, proteomics, genomics),Exceptional data visualization skills * Excellent cross-functional communication skills, including an ability to explain complex scientific concepts to a variety of audiences using a combination of plots, documents, and presentations Nice To Have: * Strong understanding of patient genetics and historical druggability of disease-relevant pathways, including experience working with patient data * Experience in efficiently advancing drug programs from proof of concept and into clinical development * Experience with immunology and inflammation clinical trial biomarker analysis Working Location & Compensation: This is an office-based, hybrid role in either our Salt Lake City, UT or New York City, NY offices. Employees are expected to work in the office at least 50% of the time. At Recursion, we believe that every employee should be compensated fairly. Based on the skill and level of experience required for this role, the estimated current annual base range for this role is $151,800 to $216,300 (USD). You will also be eligible for an annual bonus and equity compensation, as well as a comprehensive benefits package. #LI-EP1 The Values We Hope You Share: * We act boldly with integrity. We are unconstrained in our thinking, take calculated risks, and push boundaries, but never at the expense of ethics, science, or trust. * We care deeply and engage directly. Caring means holding a deep sense of responsibility and respect - showing up, speaking honestly, and taking action. * We learn actively and adapt rapidly. Progress comes from doing. We experiment, test, and refine, embracing iteration over perfection. * We move with urgency because patients are waiting. Speed isn't about rushing but about moving the needle every day. * We take ownership and accountability. Through ownership and accountability, we enable trust and autonomy-leaders take accountability for decisive action, and teams own outcomes together. * We are One Recursion. True cross-functional collaboration is about trust, clarity, humility, and impact. Through sharing, we can be greater than the sum of our individual capabilities. Our values underpin the employee experience at Recursion. They are the character and personality of the company demonstrated through how we communicate, support one another, spend our time, make decisions, and celebrate collectively. More About Recursion Recursion (NASDAQ: RXRX) is a clinical stage TechBio company leading the space by decoding biology to radically improve lives. Enabling its mission is the Recursion OS, a platform built across diverse technologies that continuously generate one of the world's largest proprietary biological and chemical datasets. Recursion leverages sophisticated machine-learning algorithms to distill from its dataset a collection of trillions of searchable relationships across biology and chemistry unconstrained by human bias. By commanding massive experimental scale - up to millions of wet lab experiments weekly - and massive computational scale - owning and operating one of the most powerful supercomputers in the world, Recursion is uniting technology, biology and chemistry to advance the future of medicine. Recursion is headquartered in Salt Lake City, where it is a founding member of BioHive, the Utah life sciences industry collective. Recursion also has offices in Toronto, Montréal, New York, London, Oxford area, and the San Francisco Bay area. Learn more at ****************** or connect on X (formerly Twitter) and LinkedIn. Recursion is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other characteristic protected under applicable federal, state, local, or provincial human rights legislation. Accommodations are available on request for candidates taking part in all aspects of the selection process. Recruitment & Staffing Agencies: Recursion Pharmaceuticals and its affiliate companies do not accept resumes from any source other than candidates. The submission of resumes by recruitment or staffing agencies to Recursion or its employees is strictly prohibited unless contacted directly by Recursion's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Recursion, and Recursion will not owe any referral or other fees. Our team will communicate directly with candidates who are not represented by an agent or intermediary unless otherwise agreed to prior to interviewing for the job.
    $151.8k-216.3k yearly Auto-Apply 27d ago
  • Senior Computational Biologist - Translational and Clinical Biomarkers

    Recursion 4.2company rating

    Saltaire, NY jobs

    Your work will change lives. Including your own. Please note: Our offices will be closed for our annual winter break from December 22, 2025, to January 2, 2026. Our response to your application will be delayed. The Impact You'll Make As a key member of Recursion's portfolio-facing data science team, you will be at the forefront of reimagining drug discovery from first principles using Recursion's massive data and compute capabilities. You will be the primary computational lead for multiple IND and clinical stage drug development programs and will be expected to use platform and patient data to advance our most promising therapeutic candidates through clinical trials. You will be responsible for the evaluation of therapeutic hypotheses using internal and external data to identify candidate biomarkers to measure in translational studies and in phase I-II clinical trials. This is a highly collaborative role: you will partner with biologists, clinicians, platform and data engineers, and translational experts to develop and scale methods that bring patient insights and reverse translation to the forefront of our medicines portfolio. The ideal candidate has strong stakeholder management, the ability to independently scope and prioritize with ambiguous or conflicting information, and is motivated to look under every stone to do the right thing for patients. In this role, you will: Evaluate the molecular evidence for predictive and PD biomarker hypotheses in translational models and clinical samples (DNA, RNA, ct DNA, and novel exploratory modalities) Pilot novel methods for patient stratification and indication selection or expansion Deliver biological insights on therapeutic candidates and disease biology from the analysis of high dimensional (phenomics, transcriptomics, patient-derived) datasets Present data analysis to decision makers and stakeholders in a clear and compelling way that drives toward getting medicines to patients Industrialize analysis approaches to not only solve for the current project, but also accelerate future projects and scale the impact that we can have Collaborate cross-functionally with Recursion's data science, platform, ML and clinical teams to further advance Recursion's ability to leverage our own clinical data in meta-analysis, hypothesis generation, and reverse translation The Team You'll Join Our group is a bold, agile, diverse collective of computational drug discovery scientists deeply focused on the singular goal of bringing new therapeutics into the clinic at an accelerated pace. You will work extensively with scientists across the organization to advance milestones, provide insights, and drive decisions that advance Recursion's capabilities and increase our likelihood of success. Essential attributes for this role include a bold, execution-first attitude and passion for deploying rigorous science to develop life-changing medicines. We partner closely with biologists, translational scientists, and clinicians to design and execute decisional data analysis for multiple programs. We are responsible for data strategy across the portfolio and are supported by computational leadership in designing scalable and reproducible experiments that advance multiple programs at once. Our team works closely with computational biologists in other therapeutic areas (neurobiology, immunology and inflammatory diseases, etc.) as well as data scientists and engineers from our core platform teams to provide a strong network of feedback and support. The Experience You'll Need PhD in a relevant field (computational biology, systems biology, bioinformatics, cancer biology, immuno-oncology, etc.) with a very strong computational focus and 3+ years of experience in biotech or pharma industry OR MS in a relevant field and 5+ years of experience in biotech or pharma industry solving fundamental problems in oncology or drug discovery Experience with high dimensional patient biomarker data from clinical trials in oncology Strong understanding of patient genetics and druggability of disease relevant pathways Experience applying computational methods (including probabilistic, statistical, and/or machine learning techniques) to analyze and integrate complex biological and/or human clinical data in a high level programming language such as Python or R Deep expertise in the analysis and data integration of two or more ‘omics data modalities (phenomics, transcriptomics, proteomics, genomics) including experience with matched clinical and molecular patient data Exceptional data visualization skills Excellent cross-functional communication skills, including an ability to explain complex scientific concepts to a variety of audiences using a combination of plots, documents, and presentations Nice To Have: Experience with late stage drug discovery and IND submission Experience collaborating cross-functionally with biometrics, statistical sciences and clinical pharmacology departments Working Location & Compensation: This is an office-based, hybrid role in either our Salt Lake City, UT or New York City, NY offices. Employees are expected to work in the office at least 50% of the time. At Recursion, we believe that every employee should be compensated fairly. Based on the skill and level of experience required for this role, the estimated current annual base range for this role is $151,800 to $216,300 (USD). You will also be eligible for an annual bonus and equity compensation, as well as a comprehensive benefits package. #LI-EP1 The Values We Hope You Share: We act boldly with integrity. We are unconstrained in our thinking, take calculated risks, and push boundaries, but never at the expense of ethics, science, or trust. We care deeply and engage directly. Caring means holding a deep sense of responsibility and respect - showing up, speaking honestly, and taking action. We learn actively and adapt rapidly. Progress comes from doing. We experiment, test, and refine, embracing iteration over perfection. We move with urgency because patients are waiting. Speed isn't about rushing but about moving the needle every day. We take ownership and accountability. Through ownership and accountability, we enable trust and autonomy-leaders take accountability for decisive action, and teams own outcomes together. We are One Recursion. True cross-functional collaboration is about trust, clarity, humility, and impact. Through sharing, we can be greater than the sum of our individual capabilities. Our values underpin the employee experience at Recursion. They are the character and personality of the company demonstrated through how we communicate, support one another, spend our time, make decisions, and celebrate collectively. More About Recursion Recursion (NASDAQ: RXRX) is a clinical stage TechBio company leading the space by decoding biology to radically improve lives. Enabling its mission is the Recursion OS, a platform built across diverse technologies that continuously generate one of the world's largest proprietary biological and chemical datasets. Recursion leverages sophisticated machine-learning algorithms to distill from its dataset a collection of trillions of searchable relationships across biology and chemistry unconstrained by human bias. By commanding massive experimental scale - up to millions of wet lab experiments weekly - and massive computational scale - owning and operating one of the most powerful supercomputers in the world, Recursion is uniting technology, biology and chemistry to advance the future of medicine. Recursion is headquartered in Salt Lake City, where it is a founding member of BioHive, the Utah life sciences industry collective. Recursion also has offices in Toronto, Montréal, New York, London, Oxford area, and the San Francisco Bay area. Learn more at ****************** or connect on X (formerly Twitter) and LinkedIn. Recursion is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other characteristic protected under applicable federal, state, local, or provincial human rights legislation. Accommodations are available on request for candidates taking part in all aspects of the selection process. Recruitment & Staffing Agencies: Recursion Pharmaceuticals and its affiliate companies do not accept resumes from any source other than candidates. The submission of resumes by recruitment or staffing agencies to Recursion or its employees is strictly prohibited unless contacted directly by Recursion's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Recursion, and Recursion will not owe any referral or other fees. Our team will communicate directly with candidates who are not represented by an agent or intermediary unless otherwise agreed to prior to interviewing for the job.
    $151.8k-216.3k yearly Auto-Apply 26d ago
  • Research Chemist (E&L)

    Nivagen Pharmaceuticals 3.7company rating

    Sacramento, CA jobs

    About the Company: Nivagen is a global company dedicated to enhancing lives by developing and providing cost-effective generic prescription drugs and over-the-counter products for the North American market. For over a decade, we've remained steadfast in our commitment to the core values of excellence, integrity, and respect for people. Our team of professionals collaborates tirelessly to pioneer advancements in manufacturing, distribution, and quality control, ensuring a holistic approach to healthcare. Through vertical integration of the pharmaceutical supply chain, cutting-edge technology, and unwavering dedication to excellence, we continually strive to redefine medication accessibility and affordability. We prioritize our employees' well-being by offering competitive pay, comprehensive benefits, and robust training and development opportunities. By investing in our workforce and fostering a culture of growth and support, we empower our team to drive innovation and make a positive impact in the healthcare industry. At Nivagen, our mission is clear: to make a meaningful difference in people's lives by delivering high-quality, affordable medications while upholding the highest standards of integrity and excellence. Job Location: Nivagen Pharmaceuticals Inc., Sacramento, CA 3900 Duckhorn Dr, Sacramento, CA 95834 About the Job: Title of the Position: Research Chemist (E&L) We are seeking an experienced Research Chemist (E&L) with a minimum of 3-5 years of pharmaceutical industry experience. Responsibilities: Maintain, operate, and troubleshoot LC-MS and GC-MS, GC-FID, and ICP-MS Systems. Perform extraction, analysis, and characterization of extractables and leachables from polymeric materials associated with container closure systems of pharmaceutical drug products as per USP, PQRI, ICH and other regulatory guidelines. Develop and optimize sample preparation techniques for analysis on GC-MS, LC-MS, and ICP-MS systems. Develop and validate LC-MS, GC-MS, and ICP-MS methods for finished product and raw material characterization as well as extractable/leachable testing. Unknown impurity identifications using GC-MS, LC-MS, and LC-MS/MS or other suitable techniques. Interpret complex spectral data and fragmentation patterns. Routine stability testing of API, finished product samples for assay and impurities using various instrumental techniques as suited, and prepare stability data summaries. Generate study designs, write protocols, methods, Datasheets and reports. Provide support in the critical review of analytical data, reports and protocols. Write Instrument-related SOPs and provide training on the instrument and related software. Train new recruits in the lab and support the team as needed. Participate in internal meetings and conferences. Provide support during technical transfer between R&D and QC. Whenever needed, attend SOP, Safety, and scientific trainings to remain current with cGMP regulations, safety standards, and development technologies. Preparation and review of analytical methods, method validation, and related study reports for ANDA/ NDA submissions and support, document preparation for ANDA/ NDA submissions. Any other activities as directed by the supervisor. Qualifications: Education/Experience: Bachelor's or Master's degree in Chemistry, Pharmaceutical Sciences, Biochemistry, or a related field. Knowledge, Skills, and Abilities: Familiarity with the characterization and isolation of impurities. Strong foundation in organic chemistry and structural elucidation, with expertise in small molecule pharmaceutical drug development and peptides, including computational techniques. Proficiency in using standard laboratory equipment, including pipettes, graduated cylinders, and balances. Skilled in laboratory techniques for measuring, weighing, and handling samples. Hands-on experience with HPLC (highly preferred). Knowledge of chemical handling procedures, including safety precautions and documentation such as Safety Data Sheets (SDS). Competency in Microsoft Office applications. Experience or familiarity with current Good Manufacturing Practices (cGMP) is preferred. Requirements: Must live or be willing to move to the Sacramento Metropolitan Region (Approximately 40 miles' radius) Benefits: Pay range $70,000 - $85,000 per Year Yearly bonus eligibility Benefits: Nivagen offers a wide variety of benefits and programs to support health and well-being Medical, dental and vision coverage Paid time off plan 401 (k) savings plan Additional Information: Nivagen to afford equal opportunity for employment to all individuals regardless of race, color, age, national origin, physical or mental disability, history of disability, ancestry, citizenship status, political affiliation, religion, gender, transgender, gender identity, marital status, status as a parent, sexual orientation, veteran status, genetic information or other factors prohibited by law, and to prohibit harassment o retaliation based on any of these factors.
    $70k-85k yearly Auto-Apply 14d ago
  • Toxicologist

    Zoetis 4.9company rating

    Kalamazoo, MI jobs

    Zoetis Veterinary Medicine Research and Development (VMRD) seeks a skilled Toxicologist to join the Toxicology Group within Clinical Pharmacology and Safety Sciences based in Kalamazoo, MI. This challenging and dynamic role provides global toxicology and safety assessment support. The successful candidate will collaborate across VMRD and Global Manufacturing and Supply (GMS) to develop scientifically rigorous safety assessments supporting product safety across therapeutic areas, veterinary species, human health, and manufacturing processes. Responsibilities: Toxicological Assessment for Drug Products: Conduct safety assessments for formulation excipients, degradants, raw materials, and residual solvents in active pharmaceutical ingredients (APIs) and drug products Toxicological Assessment for Manufacturing: Qualify impurities in the manufacturing process of APIs and drug products; conduct safety assessments for extractables and leachables, cross-contamination of products in shared facilities, and establish cleaning limits. Occupational Safety: Develop Occupational Exposure Limits (OELs/ OEBs) following Zoetis processes and procedures. User and Worker Safety: Provide product user and worker safety support for project teams, including risk assessments, exposure scenario calculations, risk mitigation proposals, packaging recommendations and label language development. Safe Exposure Level Development: Establish Threshold of Toxicological Concern (TTC) and health-based exposure limits, including Permitted Daily Exposure (PDE), Acceptable Daily Intake (ADI), and Margin of Exposure (MoE). Health Hazard/ Medical Assessments: Support pharmacovigilance, product quality, and qualification of out-of-specification batches. Regulatory Support: Assist with REACH registration for API intermediates and raw materials, and address global regulatory queries related to the safety of registered products. Toxicology Data Analysis & Literature Review: Perform rigorous toxicology gap analysis, literature data mining, and critical evaluation of toxicological information to support product development and registration. Hazard Communication and Chemical Regulatory Compliance (Preferred): Experience in preparing Safety Data Sheets (SDS), classifying drug substances and process intermediates according to the Globally Harmonized System (GHS) and national requirements, and horizon scanning and monitoring of chemical regulations. Cross-Collaboration and Technical Leadership: Engage in multidisciplinary collaboration within R&D, and with Manufacturing, Product Quality, and Sustainability, to develop and integrate key knowledge areas and expertise into actionable business insights. Regulatory & Scientific Engagement: Support regulatory compliance, trade association participation, and involvement in professional organizations relevant to toxicology. Travel Requirement: This role involves up to 10% travel for collaborations, regulatory engagements, or conferences as needed. Minimum Qualifications Ph.D. (or equivalent) plus at least 2-3 years of experience in toxicology or closely related discipline is critical. Master's degree in toxicology or closely related discipline with 8 years of relevant experience shall be considered. Demonstrated experience in preparing regulatory-quality technical documents or toxicology dossiers, with strong technical writing skills (e.g., protocols, reports, journal articles) Experience in study design, implementation, and interpretation of studies evaluating in vivo and in vitro toxicity or similar experience. Highly organized with strong problem-solving skills, capable of performing rigorous scientific assessments. Ability to prioritize tasks, make informed decisions, and collaborate effectively in a global matrix environment. Excellent verbal and written communication skills in English. Proficiency in MS Office, and toxicology databases for literature research and data analysis Desirable Skills, Experience, and Attributes: Board certification in toxicology (e.g., DABT, ERT) and/or DVM. Knowledge of global regulatory requirements for toxicology risk assessment and documentation to support product safety and chemical registrations. Experience in preparing safety data sheets. The following base pay range reflects the anticipated base pay for this position if a selected candidate were to be located in (Colorado). Base pay may vary based on location and other factors. Base Pay Range: $91,000 - $131,000 The following base pay range reflects the anticipated base pay for this position if a selected candidate were to be located in (California), (NJ Remote), (NY Remote), or (Washington). Base pay may vary based on location and other factors. Base Pay Range: $103,000 - $148,000 [This position is eligible for short-term incentive compensation.] [The position is also eligible for long-term incentive.] We offer a competitive and comprehensive benefits package, which includes healthcare, dental coverage, and retirement savings benefits along with paid holidays, vacation and disability insurance. Full time RegularColleague Any unsolicited resumes sent to Zoetis from a third party, such as an Agency recruiter, including unsolicited resumes sent to a Zoetis mailing address, fax machine or email address, directly to Zoetis employees, or to Zoetis resume database will be considered Zoetis property. Zoetis will NOT pay a fee for any placement resulting from the receipt of an unsolicited resume. Zoetis will consider any candidate for whom an Agency has submitted an unsolicited resume to have been referred by the Agency free of any charges or fees. This includes any Agency that is an approved/engaged vendor but does not have the appropriate approvals to be engaged on a search. Zoetis is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status or any other protected classification. Disabled individuals are given an equal opportunity to use our online application system. We offer reasonable accommodations as an alternative if requested by an individual with a disability. Please contact Zoetis Colleague Services at ********************************** to request an accommodation. Zoetis also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must possess or obtain authorization to work in the US for Zoetis. Zoetis retains sole and exclusive discretion to pursue sponsorship for the acquisition or maintenance of nonimmigrant status and employment eligibility, considering factors such as availability of qualified US workers. Individuals requiring sponsorship must disclose this fact. Please note that Zoetis seeks information related to job applications from candidates for jobs in the U.S. solely via the following: (1) our company website at ********************** site, or (2) via email to/from addresses using only the Zoetis domain of “@zoetis.com”. In addition, Zoetis does not use Google Hangout for any recruitment related activities. Any solicitation or request for information related to job applications with Zoetis via any other means and/or utilizing email addresses with any other domain should be disregarded. In addition, Zoetis will never ask candidates to make any type of personal financial investment related to gaining employment with Zoetis.
    $103k-148k yearly Auto-Apply 60d+ ago
  • Senior Embryologist - Wayne, PA

    IVI America 3.9company rating

    Wayne, PA jobs

    RMA of Philadelphia part of the RMA Network of top fertility clinics in the United States is seeking a Senior EMBRYOLOGIST to join our growing team in Wayne, PA. This position will be responsible for executing IVF laboratory procedures according to established policies as well as adhering to RMA's quality assurance/control operating procedures. The ideal candidate will build on previous embryology experience and train to perform all aspects of clinical embryology independently and in accordance with RMA's Laboratory Philosophy, Mission, and Performance Standards. Responsibilities: Follow established policies for IVF procedures, specimen handling, and tissue storage Maintain quality assurance, quality control, and operating guidelines for lab services Adhere to quality control policies and documentation requirements. Follow OSHA requirements for safe lab operation Obtain proficiency to perform all lab services efficiently and reliably on an independent basis Participate in clinical and research lab operations as directed Identify problems that may adversely affect patients and facilitate a solution Participate in lab proficiency testing Attend laboratory meetings as requested Attend continuing education programs as requested Requirements: Bachelor's of Science 2+ years embryology experience Demonstrate an aptitude for performance of laboratory services Aptitude to make appropriate judgments regarding clinical significance of laboratory data Excellent work ethic and motivation to learn lab procedures High level of listening and counseling skills Aptitude to work independently and demonstrate good judgment Ability to access, input, and retrieve information from a computer. Knowledge of office procedure and office machines (i.e., computer, fax, copier, etc.) Must be able to work weekends and some holidays IVI-RMA offers a comprehensive benefits package to all employees who work a minimum of 30 hours per week. Medical, Dental, Vision Insurance Options Retirement 401K Plan Paid Time Off & Paid Holidays Company Paid: Life Insurance & Long-Term Disability & AD&D Flexible Spending Accounts Employee Assistance Program Tuition Reimbursement About IVIRMA Global: IVIRMA is the largest group in the world devoted exclusively to human Assisted Reproduction Technology. Along with the great privilege of providing fertility care to our patients, IVIRMA embraces the great responsibility of advancing the field of human reproduction. IVIRMA Innovation, as one of the pillars of IVIRMA Global, is a renowned leader in fertility research and science. Check out our websites at: *********************** & *********************** EEO “IVIRMA is an Equal Opportunity Employer and Prohibits Discrimination and Harassment of Any Kind: IVIRMA is committed to the principle of equal employment opportunity for all employees and to providing employees with a work environment free of discrimination and harassment. All employment decisions at IVIRMA are based on business needs, job requirements and individual qualifications, without regard to race, color, religion and/or belief, family or parental status, or any other status protected by the laws or regulations in the locations where we operate. IVIRMA will not tolerate discrimination or harassment based on any of these characteristics. IVIRMA encourages applicants of all ages.”
    $61k-92k yearly est. Auto-Apply 59d ago
  • Animal Research Technician

    Charles River Laboratories 4.3company rating

    Research scientist job at Charles River Labs

    For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we'll help you build a career that you can feel passionate about. Job Summary We are seeking an In Vivo Technician I for our In Vivo Team at our Safety Assessment site located in Spencerville, OH. A Technician I is in training to perform and become proficient in on-boarding tasks, procedures, and cooperating in a team environment. The technician is learning basic tasks required to conduct a study, which may include collecting and recording data in the performance of studies. Responsible for handling and restraining animals, clinical observations, monitoring food consumption, animal husbandry, and performing accurate data collection and reporting. The technician is working under close supervision to gain proficiency Essential Functions (The fundamental Competencies/Skills & Responsibilities of the role (products and services provided/results accomplished) include, but are not limited to, those listed: Ensure good welfare and humane care for all animals worked with through gentle, positive human-animal interactions. Train in on-boarding tasks which may include animal handling, sexing, and restraint on multiple species as well as feeding, watering, husbandry of multiple species. Clinical observations, acclimation observations, and body weight determination on multiple species as well as qualitative and quantitative food consumption. Specific tasks will be based on each area's training plan and business needs. Collect, document, review, and verify data on forms, or in electronic data capture systems. Review documentation of functions performed as part of quality control requirements. Use and maintain instrumentation and equipment. Perform all other related duties as assigned. The pay range for this position is $19-20/hr. Please note that salaries vary within the range based on factors including, but not limited to, experience, skills, education, certifications, and location. Job Qualifications (Knowledge, Experience, Skills and Abilities required to accomplish the essential functions) include but are not limited to: Education: High school diploma or General Education Degree (G.E.D.) preferred. Associate (A.A./A.S.) or Bachelor's degree (B.A./B.S.) or equivalent in a biological science, desired. Experience: No previous experience required. An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above. Certification/Licensure: None, unless required by local government. Excellent written and verbal communication skills. Knowledge of English. Ability to manage multiple tasks and priorities to achieve goals. Computer skills (e.g., Microsoft Office Suite), commensurate with essential functions, including the ability to learn a validated system. Ability to ensure that a safe working environment is maintained by observing all safety procedures and working methods by making proper use of protective clothing and equipment, and by reading, understanding, and following all safety documents issued or notified of. Ability to ensure the integrity of the studies and fulfill the regulatory agencies requirements by performing the activities according to the Good Laboratory Practices (GLP), Standard Operating Procedures (SOP), Business Operating Procedures (BOP) and the Institutional Animal Care and Use Committee (IACUC) rules. Ability to work extended hours beyond normal work schedule to include, but not limited to evenings, weekends, extended shifts, and/or extra shifts, sometimes on short notice. Ability to work under specific time constraints. Physical Demands: Employees must be able to lift, move, manipulate, and/or hold heavy objects up to and including 50 pounds; this includes work materials, equipment, and/or animals. Must be able to perform procedures, which require, talking, hearing, standing or sitting for long periods of time, entering data into a computer, using appropriate instruments, reaching with hands and arms, working in narrow spaces, and wearing safety equipment (PPE) according to OSHA regulations and company standards. Must be able to frequently firmly hold species while utilizing fine motor skills. Specific vision abilities required by this job include close vision, color vision, depth perception, and the ability to adjust focus WORK ENVIRONMENT: Work in a research environment, which requires use of sharp objects, working around mechanical parts, working with or near known or unknown toxic or caustic chemicals and/or biological hazards, exposure to fumes and airborne particles, working at noise levels ranging from moderate to loud. The employee regularly works with live animals with risk of exposure to allergens, zoonotic disease, and biohazards. The noise level in the work environment ranges from low to high depending upon the species housed. About Safety Assessment Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market. Each year approximately 300 investigational new drug (IND) programs are conducted in our Safety Assessment facilities. About Charles River Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients' clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market. With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client's unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. At Charles River, we are passionate about our role in improving the quality of people's lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly worked on 80% of the drugs approved by the U.S. Food and Drug Administration (FDA) in the past five years. We're committed to providing benefits that elevate your quality of life. Based on your position these may include: bonus/incentives based on performance, 401K, paid time off, stock purchase program, Health and wellness coverage, employee and family wellbeing support programs, and work life balance flexibility. Equal Employment Opportunity Charles River Laboratories is an Equal Opportunity Employer - all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status. It is unlawful in some states (including Massachusetts) to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitment_**********. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications. For more information, please visit ***************
    $19-20 hourly Easy Apply 18d ago

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