Operations Manager
Charles River Laboratories job in San Diego, CA
For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we'll help you build a career that you can feel passionate about.
**JOB SUMMARY**
We are seeking an experienced Operations Manager to join our Insourcing Solutions team, located in San Diego, CA within the Charles River Accelerator & Development Labs (CRADL) animal facilities.
As the Operations Manager, you will oversee and manage all aspects of Charles River Accelerator & Development Labs (CRADL) facilities, including staff. Monitor and report on financial performance including site occupancy levels, facility expenses, capital planning, and budget. Partner with senior management to develop, implement, and achieve short- and long-term goals for the CRADL organization. Recommend innovative techniques to improve productivity, increase efficiencies, and maintain quality standards. Assure site performance is consistent with company and CRADL standards, meets or exceeds financial expectations, aligned in operations with the CRADL organization and meets client contractual requirements.
Additional responsibilities include:
+ Manages and ensures the daily husbandry and support assignments meet organizational standards & client expectations, including assigning weekend, holiday and on-call coverage conducting husbandry and services. Responsible for personnel management activities such as: mentorship, personnel actions (hiring, promotions, terminations, etc.), training & development, providing regular direction and feedback on performance, disciplinary actions, delivering annual performance and salary reviews.
+ Communicate with clients, listen to feedback/concerns and respond promptly and professionally, demonstrating strong organizational skills to manage multiple tasks, prioritize effectively, and ensure that client service operations run smoothly.
+ Serve to support key clients and assist in driving sales by supporting prospective client through presenting site capabilities or providing tours as needed.
+ Provide support to technicians in the absence of the supervisor for the following tasks as needed, coordinate personnel and facility scheduling to meet client and business needs.
+ Ensure goals and development plans are in place for all employee located at the site. Participate in talent management and succession planning.
+ Assist management with site forecasting, budget planning, client services and financial impact of client plans.
+ Conduct frequent facility inspections of all spaces to ensure high quality performance of work activities in support of client and organizational objectives, including: standards with respect to animal health and welfare, facilities condition, sanitation levels, environmental parameters and facility security are being met or exceeded.
**MINIMUM QUALIFICATIONS**
+ Bachelor's degree (B.A./B.S.) in animal or laboratory science, business, or related discipline
+ Minimum eight (8) years experience in a laboratory animal facility, of which five (5) years is management or supervisory experience.
+ AALAS certification at the Laboratory Animal Technologist level (LATG) and/or Certified Manager of Animal Resources (CMAR) _preferred_ .
Salary Transparency
The salary range for this position is $115,000 - $126,000 / annually. Please note that salaries vary within the range based on factors including, but not limited to, experience, skills, education, certifications, and location.
**About Insourcing Solutions**
Charles River Insourcing Solutionsâ„ can streamline research by delivering operational and cost efficiencies through the strategic insourcing of GMP, GLP and non-GLP research services from discovery through safety assessment. Insourcing Solutionsâ„ provides you with the ability to maintain control of your facility and expertise while leveraging available space.
**About Charles River**
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients' clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.
With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client's unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.
At Charles River, we are passionate about our role in improving the quality of people's lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly worked on 80% of the drugs approved by the U.S. Food and Drug Administration (FDA) in the past five years.
We're committed to providing benefits that elevate your quality of life. Based on your position these may include: bonus/incentives based on performance, 401K, paid time off, stock purchase program, Health and wellness coverage, employee and family wellbeing support programs, and work life balance flexibility.
**Equal Employment Opportunity**
Charles River is an equal opportunity employer and is committed to providing equal employment opportunities for all qualified applicants and employees without regard to race, color, sex, religion, national origin, ancestry, age, mental or physical disability, family status, pregnancy, military or veteran status, or any other characteristic protected by federal, state, or local laws.
It is unlawful in some states (including Massachusetts) to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitment_**********. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.
For more information, please visit ***************
229946
Easy ApplyAnimal Care Technician II
Charles River Laboratories job in San Diego, CA
For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we'll help you build a career that you can feel passionate about.
**Job Summary**
We are seeking an Animal Care Technician II to join our Insourcing Solutions team, located in San Diego, CA.
As the Animal Care Technician II, you will perform animal care and husbandry duties on rodent species in accordance with AAALAC standards and client's SOPs/policies. Observe, monitor, and document the health and physical environment within the client's animal facility. Perform a variety of technical procedures on research rodents.
Additional responsibilities include:
+ Review, comprehend and comply with all SOPs, guidelines/policies, training provided both verbally and written, protocols, and quality assurance standards pertaining to assigned responsibilities and to the care and use of laboratory animals for research.
+ Monitor daily animal health and welfare while performing daily animal health observations utilizing an assigned iPAD or tablet device.
+ Perform animal husbandry duties to maintain quality and health of research animals, to include: perform daily water bottle / automatic water line and cage checks; provide appropriate food and water; perform cage changing and/or cage cleaning as required; record animal health concerns per SOP and/or specified protocols.
+ Maintain accurate room maintenance records and other required record-keeping documentation as required by department SOPs and/or guidelines/policies.
+ Work closely with client's Veterinarians and Veterinary Staff, assist with animal sample collection and other _in vivo_ procedures as assigned by the on-site facility veterinarian or veterinary staff member.
+ Provide service daily to the researchers to ensure study animals receive medicated diet and/or medicated water and any other special housing requests outlined in their study protocol. Direct communication and interaction may be required between employee and researcher.
**Other Responsibilities**
+ Perform a variety of technical procedures on rodents, such as, ear tagging, shaving, blood collection, tissue sampling, etc.
+ Strictly follow all procedures necessary to maintain animal housing areas or isolator environments, including room or facility personnel entry and personal protective equipment use, biosecurity procedures, and safety procedures.
+ Receive, inspect, and house incoming animals; care for and provide for sentinel-free soiled bedding collection cages in each rodent housing area as required by department SOPs, guidelines/policies, and protocols.
+ Operate equipment and use supplies according to safety guidelines; perform general housekeeping and adheres to safety procedures.
+ Maintain required attendance level and adherence to assigned work schedule in accordance with required staffing levels in order to ensure that assigned duties are completed to client standards.
+ Assists with the receipt, stocking inventory, and maintenance of supplies.
+ Perform all other related duties as assigned.
**Job Qualifications**
+ To qualify for this role, candidates must have one of the following combinations of education/experience:
+ HS/GED and 1 year directly related lab animal experience.
+ AA/AS and 6 months directly related lab animal experience.
+ BA/BS in animal or life sciences, no experience required.
+ Certification/Licensure: AALAS certification at the ALAT level preferred
+ Schedule will be 6:00 a.m. - 2:30 p.m., Sunday - Thursday or Tuesday - Saturday
The pay range for this position is $27-29 USD per hour. Please note that salaries vary within the range based on factors including skills, certifications, and location.
Knowledge, Skills and Abilities
+ Proficiency with basic animal identification and handling methods.
+ Ability to effectively follow verbal and written instructions and exhibit interpersonal skills that are conducive to effective communication and that contribute to a congenial work environment. Maintain a positive work atmosphere by behaving and communicating in a professional manner with coworkers, research staff, and management.
+ Strong organization skills and attention to detail. Strong written and verbal English communication skills. Proficiency with computers and software documentation systems, including good working knowledge of Microsoft Word and Excel.
**Physical Demands**
+ While performing the duties of this job, the employee is regularly required to stand, use hands and fingers to handle, feel, or use objects, tools, or controls, and reach with hands and arms. The employee is frequently required to walk, stoop, kneel, crouch, or crawl. The employee is occasionally required to sit. The employee is frequently required to type at a computer or tablet/iPAD. The employee must regularly lift and/or move up to 50 pounds. Occasionally lift and/or move up to 100 pounds.
+ Specific vision abilities required by this job include close vision, distance vision, peripheral vision, depth perception, and the ability to adjust focus. The employee is regularly required to talk and/or hear.
Work Environment
+ While performing the duties of this job, the employee frequently works near or with moving mechanical parts and robotics and is frequently exposed to laboratory animals and caging of various species including mice, rats, and other small animals. The employee is frequently exposed to wet and/or humid conditions, fumes or airborne particles, toxic or caustic chemicals, animal allergens, biohazard materials and risk of electrical shock. The noise level in the work environment is usually loud and may require hearing protection.
**About Insourcing Solutions**
Charles River Insourcing Solutionsâ„ can streamline research by delivering operational and cost efficiencies through the strategic insourcing of GMP, GLP and non-GLP research services from discovery through safety assessment. Insourcing Solutionsâ„ provides you with the ability to maintain control of your facility and expertise while leveraging available space.
**About Charles River**
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients' clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.
With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client's unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.
At Charles River, we are passionate about our role in improving the quality of people's lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly worked on 80% of the drugs approved by the U.S. Food and Drug Administration (FDA) in the past five years.
We're committed to providing benefits that elevate your quality of life. Based on your position these may include: bonus/incentives based on performance, 401K, paid time off, stock purchase program, Health and wellness coverage, employee and family wellbeing support programs, and work life balance flexibility.
**Equal Employment Opportunity**
Charles River is an equal opportunity employer and is committed to providing equal employment opportunities for all qualified applicants and employees without regard to race, color, sex, religion, national origin, ancestry, age, mental or physical disability, family status, pregnancy, military or veteran status, or any other characteristic protected by federal, state, or local laws.
It is unlawful in some states (including Massachusetts) to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitment_**********. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.
For more information, please visit ***************
231517
Easy ApplyAdvisor / Sr. Advisor - Protein Expression
San Diego, CA job
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
The Biotechnology Discovery Research group located in both San Diego and Indianapolis discovers medicines that address significant unmet needs by integrating biology with innovative scientific capabilities in protein discovery, production and characterization, and engineering. We collaborate with colleagues in both the discovery and development organizations, including scientists in therapeutic area biology, biomolecule formulation and developability, ADME, Toxicology, PK/PD, Statistics, Computational Sciences, Clinical Development, and more. Our team has more than 25 years of experience discovering and developing antibodies, proteins, and peptide therapeutics.
We are looking for a motivated and independent researcher with a strong background in protein expression to design and execute efficient gene-to-protein workflows, aimed at producing innovative therapeutic proteins and research reagents. The individual selected for this role will collaborate with a team of expression and purification scientists and matrixed project teams to foster innovation and advance our biotherapeutic discovery portfolio.
Responsibilities:
* Design and produce novel therapeutic proteins and research reagents using various expression systems, including mammalian (CHO and HEK293), bacterial, and insect cells to support antibody/peptide discovery projects
* Evaluate and implement new methods for protein expression to expand the team's capabilities and productivity through partnership with automation, downstream purification/analytical teams, and external collaborations
* Provide critical insights into antigen design for antibody discovery and structural studies, leveraging AI/ML approaches and large data sets to accelerate breakthroughs.
* Enhance project team engagement as protein expression subject matter expert by partnering with dynamic, cross-disciplinary teams to tackle exciting scientific challenges in material generation. Your expertise will drive the creation of novel therapeutic proteins and research reagents, directly supporting antibody and peptide discovery projects.
* Maintain a current knowledge in the field, provide training and guidance to junior team members.
Basic Qualifications:
* Ph.D. in biochemistry, molecular biology, cell biology, or related field with >2 years of relevant experience beyond education/postdoctoral training in a pharmaceutical, biotech, or research organization
Skills/Preferences:
* Extensive hands-on experience with recombinant protein and antibody expression in mammalian (HEK293, CHO) systems at various scales between a few mgs to grams
* Proven expertise in the expression of complex biomolecules, such as bispecific antibodies and fusion proteins, with a strong track record of resolving intricate expression-related issues through effective troubleshooting and optimization strategies.
* Experience with microbial systems (E. coli, yeast) and cell free expression is a plus
* Proficiency in expression construct optimization (codon optimization, vector design, promoter selection, tag selection)
* • Experience establishing and optimizing high-throughput protein expression workflows
* Strong knowledge in structure-based protein/antigen design and production is highly desired
* Experience in protein purification and characterization, including the use of advanced automation platforms for the efficient production of proteins and antibodies, is preferred
* A solid grasp of the biologics drug discovery process, encompassing key stages such as target identification, lead optimization, and preclinical development, is beneficial
* Team player with strong organizational skills ready to work effectively with cross-functional colleagues across geographies in a collaborative, fast-paced environment
* Proven ability to manage and develop scientific staff
* Track record of cross-functional collaboration with discovery biology, protein engineering, and developability teams
* Excellent written and verbal communication skills, ability to prioritize work and meet targeted timelines and deliverables.
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (******************************************************** for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.
Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), en Able (for people with disabilities). Learn more about all of our groups.
Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is
$138,000 - $224,400
Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
#WeAreLilly
Auto-ApplyIn Vivo Pharmacologist- Immunology
San Diego, CA job
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
At Lilly's Biotechnology Center in San Diego, the in vivo immunology group contributes to the advancement of the immunology portfolio by creating innovative in vivo models to interrogate complex biology. Our collaborative efforts span across both discovery and development organizations, working closely with scientists specializing in immunology, bioengineering, chemistry, biomolecule formulation and developability, genetic medicines, and other related disciplines to drive immunology research and therapeutic development.
We seek an in vivo scientist who will lead research studies focused on understanding immunological mechanisms using advanced in vivo models to enable drug discovery efforts. The ideal candidate will demonstrate expertise in humanized mouse systems, particularly with CD34+ hematopoietic stem cell engraftment. Responsibilities include model development and execution, analyzing data, and collaborating with multidisciplinary teams to advance therapeutic development. Strong experience with immunophenotyping, in vivo assay development, and interpretation of preclinical data is essential. Strong interpersonal skills and the ability to excel in a highly collaborative environment are vital.
Responsibilities:
Provide strong scientific and technical leadership to establish and innovate in in vivo models to interrogate mechanisms and pathways relevant to the discovery of novel treatments for autoimmune diseases and related pathologies.
Be hands-on in the laboratory to leverage and develop in vivo and in vitro systems to generate critical data supporting new and existing programs. Must be skilled with human CD34+ hematopoietic stem cell engraftment.
Function independently, work within a team-oriented lab environment and communicate results to cross functional discipline teams.
Provide supervision and mentoring to 1-2 scientists, performance evaluations, and career development.
Requirement for accurate record keeping, independent data analysis, and reporting of data in written and oral formats. Will perform work in full compliance with Lilly Research Policies and complete all required training activities in the timeframe specified.
Basic Qualifications/Requirements:
Ph.D. in physiology, immunology, biology, pharmacology, or a closely related field
1- 2 years' experience with in-vivo capabilities and human CD34+
Additional Skills/Preferences:
Strong/extensive in vivo capabilities
Skilled in the art of human CD34+ hematopoietic stem cell engraftment into mice and execution of downstream studies.
Proficient in cell isolation, cell culture, and immune cell differentiation procedures
Knowledgeable with ex vivo sample assays and analyses (e.g. ELISA, RNA isolation, Nanostring)
Familiarity with FACS and immunophenotyping
Ability to prioritize activities across multiple projects independently and effectively while demonstrating initiative and appropriate risk taking.
Excellent communication and organizational skills are required to present findings in internal and external forums.
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (******************************************************** for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.
Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), en Able (for people with disabilities). Learn more about all of our groups.
Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is
$138,000 - $224,400
Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
#WeAreLilly
Auto-ApplyAdvisor - Lab Automation Software Engineer
San Diego, CA job
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
We are seeking a Lab Automation Software Engineering Advisor to join our biotherapeutics discovery automation team at the Lilly Biotechnology Center in San Diego, where you'll architect and implement revolutionary software solutions that transform how we discover life-saving biotherapeutics.
As a Lab Automation Software Engineering Advisor, you'll be at the forefront of designing and building AI-integrated, closed-loop autonomous discovery ecosystem whereby intelligent systems propose hypotheses, execute experiments through advanced robotics, analyze results instantly, and iteratively refine and design the next set of experiments - all with minimal human intervention. In your role, you'll harness the latest breakthroughs in AI, machine learning, and laboratory digitalization to build software that makes our biotherapeutics discovery automation lab smarter, faster, and more innovative than ever before.
If you're excited about harnessing AI and automation to solve real-world problems in drug discovery and want to be part of building the lab of the future, we want to hear from you.
You will have the opportunity to:
Design and develop software applications that orchestrate complex automated laboratory workflows and closed-loop learning systems.
Build data pipelines and visualization tools that provide real-time insights into lab operations and experimental outcomes.
Implement machine learning models for visual inspection systems, predictive maintenance, and process optimization that enhance operational efficiency.
Create digital lab infrastructure including IoT integrations, digital lab twin models, and telemetry monitoring systems.
Develop and maintain integrations across multiple automation schedulers, LIMS, and data platforms.
Ensure robust software deployment through best DevOps practices and cloud-based solutions.
Basic Qualifications:
Ph.D. in Computer Science, Software Engineering, Bioengineering/Engineering with at least three years of industry experience.
M.S. in Computer Science, Software Engineering, Bioengineering/Engineering with at least 10 years of experience.
B.S. in Computer Science, Software Engineering, Bioengineering/Engineering with at least 13 years of experience.
Experience should include relevant industry experience, preferably in a pharmaceutical company or an automation provider.
Additional Skills/Preferences:
Strong proficiency in Python, SQL, and JavaScript, with working knowledge of programing/scripting in C#, VBA, R, C++, MATLAB, and Bash.
Experience with statistical analysis tools (JMP, SAS, R) and business intelligence platforms (Tableau, Power BI, Spotfire).
Expertise in best DevOps practices, including database management systems (DBMS), data warehousing, software development, cloud computing platforms (AWS, Azure), and version control tools (GitHub, GitLab).
Experience with lab digitalization technologies (IoT device integration, digital lab twins, automated usage and error reporting telemetry metrics) as well as autonomous lab systems and closed-loop learning frameworks is strongly preferred.
Familiarity with lab data platforms including Benchling, LabGuru, PostgreSQL, Genedata, or similar LIMS/ELN systems.
Strong problem-solving skills and ability to work cross-functionally with scientific and engineering teams.
Background in life sciences, pharmaceutical research, or high-throughput screening environments.
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (******************************************************** for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.
Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), en Able (for people with disabilities). Learn more about all of our groups.
Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is
$141,000 - $228,800
Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
#WeAreLilly
Auto-ApplyEnvironmental Health and Safety Specialist
Charles River Laboratories job in San Diego, CA
For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we'll help you build a career that you can feel passionate about.
**Job Summary**
We are seeking an Enironmental Health & Safety Specialist to join our Insourcing Solutions team, located in San Diego, CA.
As the EH&S Specialist, you will be responsible for: managing EHS programs in adherence to local, state and federal regulations at CRADL facilities. Assist in program development unique to CRADL facilities, staff and client needs and participate in growing site expansion portfolio for the CRADL business. This role requires excellent interpersonal skills and a willingness to lead teams of people in projects and implementation of sustainable processes that will improve the health and safety of our employees. The individual in this role is a generalist and may be responsible for programs across the EHS discipline and will be responsible for training staff.
Additional responsibilities include:
+ Establish, administer, and update specific EH&S programs for compliance with state and federal Occupational Safety and Health Administration (OSHA), Environmental Protection Agency (EPA), Department of Transportation (DOT) and other regulations as necessary. Manage OSHA and EPA records and maintain reporting and documentation standards.
+ Provide initial and periodic safety and environmental training to all employees and CRADL clients as required and advise management on safety and environmental issues. Review new regulatory standards and make compliance recommendations.
+ Inspect the facilities for compliance with OSHA and EPA regulations as applicable. Recommend solutions to management that address deficiencies in EH&S compliance.
+ Periodic observations of CRADL clients performing work with hazards to ensure post-IACUC approval compliance. Liaise with clients for work consultations and recommendations for studies.
+ Implement and maintain EH&S programs and metrics.
+ Perform documented risk assessments for the CRADL business.
+ Oversee maintenance of group training manual, in-person training, and training records for CRADL clients and staff.
+ Develop and ensure adherence to pertinent regulatory requirements and to departmental policies, practices, and procedures (SOPs, safety procedures, biosafety protocols, biohazard, and medical waste).
Additional Responsibilities Continued
+ Serve as an EHS pre-reviewer for all CRADL IACUC protocols.
+ Assist in CRADL AAALAC Accreditation process for all existing and new sites.
+ Manage the hazardous waste (RCRA) and medical waste disposal function including waste profiling, permitting, manifesting, and record keeping and reporting.
+ Assist management team in emergency response and function as EH&S Emergency Coordinator for 24-hour incident response.
+ Assist in the investigation of injuries resulting in lost time claims and/or safety violations and property damage. Make recommendations for corrective action. Provide regulatory guidance on EH&S issues to all staff.
+ Available to clients and federal and state investigators to explain procedures and produce written documentation as proof of compliance.
+ Manage and maintain necessary facility permit, licenses, and compliance reports to federal, local, and state regulatory authorities for all CRADL sites and ensure new sites are permitted and in compliance appropriate for the region.
+ Assist in the basis of design of new CRADL facilities including, but not limited to, oxygen depletion assessments, monitoring and alarm requirements for hazardous gases, and waste systems.
+ Coordinate communications to regulatory agencies and client inspections on EH&S related matters.
+ May assist in development of departmental budget.
+ Support the policy of equal employment opportunity through affirmative action in personnel actions.
+ Attend and participate in on-the-job and classroom training sessions and complete all assigned computer-based safety and professional development training by predetermined due dates.
+ Perform all other related duties as assigned.
**Job Qualifications**
Education:
+ Bachelor's degree or equivalent in Environmental Health and Safety, Environmental Engineering, or a related discipline.
Experience:
+ Minimum of five (5) years related experience in Environmental Health & Safety. Experience supporting laboratory animal facilities preferred. Experience in multiple state regulations, including California, preferred.
Knowledge, Skills & Abilities:
+ Demonstrated ability to interpret/apply required federal or state regulations and manage multiple/changing priorities with many interruptions.
+ Excellent commutation skills both verbal and written, project management skills, and strong time management and organizational skills are required.
+ Basic familiarity with Microsoft Office Suite.
+ Computer skills, commensurate with Essential Functions, including the ability to learn a validated system.
+ Ability to work extended hours beyond normal work schedule to include, but not limited to evenings, weekends, extended shifts, and/or extra shifts; sometimes on short notice.
+ Ability to work under specific time constraints.
Compensation Data
The pay range for this position is $95,000 - $110,000. Please note that salaries vary within the range based on factors including, but not limited to, experience, skills, education, certifications, and location.
**About Insourcing Solutions**
Charles River Insourcing Solutionsâ„ can streamline research by delivering operational and cost efficiencies through the strategic insourcing of GMP, GLP and non-GLP research services from discovery through safety assessment. Insourcing Solutionsâ„ provides you with the ability to maintain control of your facility and expertise while leveraging available space.
**About Charles River**
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients' clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.
With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client's unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.
At Charles River, we are passionate about our role in improving the quality of people's lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly worked on 80% of the drugs approved by the U.S. Food and Drug Administration (FDA) in the past five years.
We're committed to providing benefits that elevate your quality of life. Based on your position these may include: bonus/incentives based on performance, 401K, paid time off, stock purchase program, Health and wellness coverage, employee and family wellbeing support programs, and work life balance flexibility.
**Equal Employment Opportunity**
Charles River Laboratories is an Equal Opportunity Employer - all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, or national origin, veteran or disability status.
It is unlawful in some states (including Massachusetts) to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitment_**********. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.
For more information, please visit ***************
231053
Easy ApplyIn Vivo Biologist- Immunology
San Diego, CA job
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
Organizational Overview: Lilly Immunology Discovery is dedicated to identifying novel therapeutics to treat the myriad of autoimmune diseases impacting patients around the globe. We are currently seeking a motivated biologist to work as an integral part of our immunology in vivo pharmacology group. The main responsibility of this group is to develop and validate disease models of inflammation and autoimmunity for the interrogation of novel therapeutics within Lilly Immunology Discovery. Located at the Lilly Biotechnology Center in San Diego, our pharmacology group supports projects directed both in San Diego, Boston, and the Corporate Center in Indianapolis.
Responsibilities: This position requires prior experience in the development of small animal models of inflammation and conducting in vivo efficacy studies according to study protocols. The candidate will be responsible for all aspects of the in-life portions of studies and be involved in post study sample processing and data analysis. In addition, the position will perform in vitro assays of study tissue samples. The applicant should desire to work in a team environment as the position must work in unity with other members of the pharmacology group and interact with various immunology members and cross-functional colleagues.
* Perform all aspects of in vivo experiments: dose formulation, animal handling, dosing (PO, IP, SC, ID, IV), blood collection, small animal surgery, and tissue collection/processing and the planning thereof within the pharmacology team.
* Analyze and graph data for review.
* Perform ELISAs (or similar platform) on study samples.
* Organize data and present findings at team meetings.
Requirements:
* BS or MS in physiology, biology, pharmacology or closely related field with 2+ years of in vivo experience.
Additional Skills/Preferences
* Skilled in dose formulation, animal handling, blood collection, animal surgery, and tissue collection/processing.
* Experienced using Excel and GraphPad Prism for analysis and statistics
* Diligent record keeping
* Ability to design, analyze, and interpret study results
* Good organizational and communication skills. The position will be required to present results in internal meetings.
* Knowledge of molecular biology (e.g. RNA isolation, RT-PCR).
* Familiarity with imaging processes (IHC/IF, IVIS, Phenocycler), FACS analysis and FloJo, and/or cell culture techniques a plus.
Additional Information: This position will require occasional weekend work
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (******************************************************** for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.
Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), en Able (for people with disabilities). Learn more about all of our groups.
Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is
$71,250 - $187,000
Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
#WeAreLilly
Auto-ApplySr. Director - Clinical Development
San Diego, CA job
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
Company Overview
At Lilly, we serve an extraordinary purpose. For more than 140 years, we have worked tirelessly to discover medicines that make life better. These discoveries start in Lilly Research Laboratories, where our scientists work to create new medicines that will help solve our world's greatest health challenges.
Purpose:
This CRP role within the Immunology gastroenterology therapeutic area will support early and late phase clinical trials for assets in the gastroenterology pipeline. Through the application of scientific and medical training, clinical expertise, and relevant clinical experience, the Development Clinical Research Physician (CRP) participates in: the development, conduct and reporting of corporate/global clinical trials in support of registration and commercialization of the product; the implementation of global clinical trials; the reporting of adverse events as mandated by corporate patient safety; the review process for protocols, study reports, publications and data dissemination for products, new and updated labels, documents and tools supporting product pricing, reimbursement, and access (PRA), grant submissions and contracts; contacts with regulatory and other governmental agencies; outreach medical activities aimed at the external clinical customer community, including thought leaders; the development and implementation of the business unit and global strategy for the product; and various medical activities in support of demand realization.
The Clinical Research Physician serves as a scientific resource for study teams, departments, and others as needed. The Clinical Research Physician must be aware of and ensure that all activities of the medical team are in compliance with current local and international regulations, laws, guidance's (for example, FDA, ICH, CPMP etc.), Good Clinical Practices (GCPs), company standards, Lilly policies and procedures, company integrity agreements as applicable, and the Principles of Medical Research and activities are aligned with the medical vision.
Primary Responsibilities:
This is intended to provide a general overview of the job requirements at the time it was prepared. The job requirements of any position may change over time and may include additional responsibilities not specifically described in the job description. Consult with your supervision regarding your actual job responsibilities and any related duties that may be required for the position.
The primary responsibilities of the Development CRP are generally related to late-phase and marketed compounds. The core job responsibilities may include those listed below as deemed appropriate by line management, as well as all other duties as assigned.
Clinical Planning
* Collaborate with the business unit geographical regions, Discovery, Program Phase Medicine, and Clinical Pharmacology in the development and maintenance of a Draft Launch Label and Value Proposition that addresses key customer needs (patient, provider, and payer); the product lifecycle plan, clinical strategies, development plans and study protocol design.
* Contribute to business unit and global alignment of clinical strategy and clinical plans.
* Understand and keep updated with the pre-clinical and clinical data relevant to the molecule.
Clinical Research/Trial/ Execution and Support
* Plans, collaborates on and reviews scientific content of clinical documents such as protocols, informed consent documents, final study reports, and submissions (e.g., annual reports) according to the agreed upon project timeline.
* Provide protocol oversight and input into informed consent documents.
* Collaborate with clinical research staff in the design, conduct and reporting of local clinical trials (for example, sample size, patient commitment, timelines, grants, and governance review interactions).
* Review and approve risk profiles to ensure to ensure appropriate communication of risk to study subjects.
* Participate in investigator identification and selection, in conjunction with clinical teams.
* Ensure that operational team has documented the completion of administrative requirements for study initiation and conduct (for example, ethical review board, informed consent, regulatory approval/notification) consistent with Good Clinical Practices (GCPs) and local laws and requirements.
* Assist in planning process and participate in study start-up meetings and other activities to provide the appropriate training and information to investigators and site personnel.
* Serve as resource to clinical operations/CTMs/ clinical research monitors, investigators and ethical review boards to address any questions or clarify issues arising during the conduct of study.
* Understand and actively address the scientific information needs of all investigators and personnel.
* Monitor patient safety during the conduct of studies and conduct the appropriate tracking and follow-up of adverse events, in alignment with corporate patient safety policies and procedures.
* Review lIT proposals and publications, as requested by Director-Medical.
Scientific Data Dissemination/Exchange
* Knowledge of and compliance with local laws and regulations, and global policies and procedures, compliance guidelines with respect to data dissemination and interactions with external health care professionals.
* Understand and address the unsolicited scientific information needs of external health care professionals according to guidelines above.
* Participate in reporting of clinical trial data in Clinical Trial Registry activities.
* Support the planning of symposia, advisory board meetings, and other meetings with health care professionals.
* Support medical information associates in preparation and review of medical letters and other medical information materials.
* Prepare or review scientific information in response to customer questions or media requests
* Provide telephone follow-up or specific written information requested by health care professionals as per global SOPs.
* Support data analysis and the development of slide sets (through reviewing and/or approving) and publications (abstracts, posters, manuscripts).
* Establish and maintain appropriate collaborations and relationships with external experts, thought leaders, and the general medical community on a local, national, regional and possibly international basis.
* Develop and maintain appropriate collaborations and relationships with relevant professional societies.
* Support the design of customer research as medical expert
* Support training of medical personnel, including geographic/affiliate medical personnel as assigned, medical and outcome liaisons and global patient outcomes personnel.
* Provide congress support (for example, availability to answer questions at exhibits, provide oral and poster presentations, staff medical booth, meet thought leaders, and participate in customer events)
* Participate in data analysis, development of scientific data dissemination, and preparation of final reports and publications.
Regulatory Support Activities
* Participate in development and review of label changes and labeling modifications in collaboration with affiliates, brand teams, regulatory, and legal.
* Provide medical expertise to regulatory scientists.
* Support/assist in the preparation of regulatory reports, including NDAs, FDA annual reports and Periodic Adverse Drug Experience Reports (PADERS), preparation for FDA advisory committee hearings and label discussions, local registration efforts, and communication and resolution of regulatory issues, including regulatory response, from a global perspective.
* Participate in advisory committees.
* Participate in risk management planning along with affiliates and Global Patient Safety (GPS).
Business/ customer support (ore and post launch support)
* Contribute to the development of medical strategies to support brand commercialization activities by working closely with business unit, brand team, clinical plans manager/project management associates and other cross-functional management during the development of the local business plan.
* Understand and anticipate the scientific information needs of all Development customers (payers, patients, health care providers).
* Actively address Development customer (payer, patient, and health care providers) questions in a timely fashion by leading data analyses and new clinical or global patient outcomes research efforts.
* Establish effective collaborations with marketing personnel in the various geographic regions to further corporate demand realization.
* Establish and maintain contact with external experts and opinion leaders; maintain a credible scientific expertise to facilitate these contacts.
* Contribute as a scientific and medical expert to activities and deliverables of the PRA organization, in particular giving clinical input and insight to develop payer partnership programs and defend the product value.
* Support business-to-business and business-to-government activities as medical expert.
* Contribute actively on an ongoing basis to the strategic planning for the brand.
* By offering scientific and creative input, contribute to the development, review, and approval of promotional materials and tactics as needed.
* Become familiar with market archetypes and potential influence on the medical interventions for the product.
* Take a leadership role in defining the Patient Journey and corresponding Moments of Truth based on his/her medical knowledge. Become a patient advocate, as well as a medical expert.
* Participate in PhRMA or other local or national trade associations as appropriate.
Scientific I Technical Expertise and continued development
* Critically read and evaluate the relevant medical literature; know the status and data from competitive products; and keep updated with medical and other scientific developments relevant to the product
* Be aware of current trends and projections for clinical practice and access in the therapeutic area(s) relevant to the product, both near term (1-2 years) and longer term (3-5 years).
* Responsible for the scientific training of the clinical study team.
* Acts as scientific consultant and protocol expert for clinical study team members and others in medical.
* Explore and take advantage of opportunities for extramural scientific experiences
* Attend scientific symposia
General Responsibilities
* Support the management team, including the Sr. Director-Medical, in preparation and administration of the business unit development budget.
* Actively set and meet individual professional development goals and contribute to the development of others.
* Actively participate in recruitment, diversity and retention efforts.
* Collaborate proactively and productively with all alliance, business and vendor partners.
* Participate in active coaching by providing timely and constructive feedback to co-workers, others on the medical team, in the spirit of development, increased team effectiveness and cohesiveness.
* Participate in committees, Six Sigma initiatives and task forces as requested by local/corporate management
* Ensures that at all times is adequately qualified and trained in the tasks required to perform. Includes accountability and compliance for maintaining a current curriculum training map for self.
* Model the leadership behaviors
* Be an ambassador of both patients and the Lilly Brand
Minimum Qualification Requirements:
* Medical Doctor or Doctor of Osteopathy. Must be board eligible or certified in appropriate specialty/subspecialty or have completed the comparable level of post-medical school clinical training relevant to the country of hiring. US trained physicians must have achieved board eligibility or certification. Physicians trained outside the US who are not US board eligible or certified may be hired directly for employment in the US at the discretion of the Chief Medical Officer.
* Non-US trained physicians must have completed education and training at a medical school that meets the requirements of the Liaison Committee on Medical Education (LCME). For the recognized list of foreign medical schools and the disapproved list, see PLA: Medical Licensing Information and Medical Education | MBC
Preferred Qualifications:
* Demonstrated ability to balance scientific priorities with business priorities with examples of successful leadership skills
* Demonstrated strong communication, interpersonal, teamwork, organizational, and negotiation skills
* Demonstrated ability to influence others (both cross-functionally and within the function) in order to create a positive working environment.
* Ability to engage in domestic and international travel to the degree appropriate to support the business of the team.
* Fluent in English, verbal and written communication
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (******************************************************** for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.
Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), en Able (for people with disabilities). Learn more about all of our groups.
Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is
$217,500 - $389,400
Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
#WeAreLilly
Auto-ApplyVeterinary Technician II
Charles River Laboratories job in San Diego, CA
For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we'll help you build a career that you can feel passionate about.
**Job Summary**
We are seeking an experienced Veterinary Technician II to join our Insourcing Solutions team, located in San Diego, CA.
As the Veterinary Technician II under the direction of the client's Veterinarians and veterinary staff, you will maintain and monitor the health and physical environment of client's animals involving complex instructions and requiring technical expertise. Assist veterinary staff in the documentation and triage of all laboratory animal health cases. May also perform basic and advanced technical in-life procedures.
Additional responsibilities:
+ Assist client's Veterinarians in the documentation and triage of all animal health cases noted by technical staff and/or Attending Veterinarian.
+ Conduct regular clinical rounds and routine health monitoring and examinations in support of studies and in accordance with the requirements of the research program, and assure the implementation of preventive measures such as environmental enrichment, hydration support, etc.
+ Assist in investigations, as needed, on reports of animal health issues and/or conditions suggesting problems with animal well-being, as directed by the Attending Veterinarian. As appropriate, recommend, administer, and record (following coordination with study directors) routine treatment of animals. Generate summary reports as necessary.
+ Perform and document appropriate clinical observations. Ensure corrective actions for health or welfare issues are developed and implemented in accordance with the research programs.
+ Notify veterinary staff, study directors, and other appropriate personnel of conditions that are indicative of pain and distress or other abnormal findings that could lead to such conditions or compromise studies.
**Responsibilities continued:**
+ Perform routine veterinary technical and husbandry skills including the following:
+ Administration of various therapeutic measures by IV, IM, SQ, topical, oral routes, etc.
+ Venipuncture techniques and other sample collection
+ Mouse reproductive care, such as plug checks or litter checks
+ Proficient animal restraint techniques
+ Nail trimming
+ Monitor and assess critical animals
+ Perform animal follow-up observations or new findings as required.
+ Monitor animal health, visually, and by following detailed schedules.
+ Generate animal treatment records and perform, track and schedule follow-ups.
**Responsibilities continued:**
+ Maintain appropriate medical records for each animal in accordance with study and regulatory requirements.
+ Assist in maintaining accurate record keeping procedures for the veterinary department.
+ Maintain and follow complex procedures to ensure appropriate animal health and treatment.
+ Provide input into the creation/revision of SOPs and assist in implementation and training of new SOPs.
+ Assist in providing and supporting a culture of care, including animal health training, and guidance to less experienced technical staff and other laboratory personnel.
+ Assist in keeping inventory and stocking the vet rooms (i.e., drugs and supplies). Assist in organizing and maintaining the vet procedures rooms.
+ May be responsible for tissue sampling, routine animal manipulations and administration of fluids or other treatments as required.
+ May perform routine technical and husbandry functions (general housekeeping) on studies and must adhere to safety procedures.
+ Assist in surgery and peri-surgery care, e.g. provide and monitor anesthesia, prepare surgical packs, administer supportive therapy.
+ Perform all other related duties as assigned.
**Job Qualifications:**
+ _Education:_ Associate degree (A.A./A.S.) or Bachelor's degree (B.A./B.S.) or equivalent in animal or laboratory science, business, or related discipline.
+ _Experience:_ Minimum of two - three (2 - 3) years of veterinary experience or six - twelve (6 - 12) months directly related laboratory animal experience in a laboratory animal facility.
+ _Certification/Licensure:_ LaboratoryAnimal Technician (LAT) certification from AALAS. Laboratory Animal Technologist (LATG), CVT, LVT, or RVT certification preferred.
+ _Other:_ Demonstrate understanding of Standard Operating Procedures. Excellent organizational, time management and recordkeeping skills. Basic word processing skills required. Excellent communication skills both written and verbal. Must be proficient in routine veterinary technical and husbandry techniques.
+ _Shift_ : Monday - Friday, 7:00 a.m. - 3:30 p.m. Weekends and holidays may be required as needed.
The pay range for this position is $32 - 34 USD per hour. Please note that salaries vary within the range based on factors including experience, skills, education, certifications, and location.
**Physical Demands:**
+ Employees must be able to lift, move, manipulate, and/or hold heavy objects up to and including 25 pounds; over 50 pounds with assistance; this includes work materials, equipment, and/or animals.
+ Must be able to perform procedures, which require, talking, hearing, standing or sitting for long periods of time, entering data into a computer, using appropriate instruments, reaching with hands and arms, working in narrow spaces, and wearing safety equipment (PPE) according to OSHA regulations and company standards.
+ Must be able to frequently firmly hold species while utilizing fine motor skills.
+ Specific vision abilities required by this job include close vision, color vision, depth perception, and the ability to adjust focus.
Work Environment:
+ Works in a research environment, which requires use of sharp objects, working around mechanical parts, working with or near known or unknown toxic or caustic chemicals and/or biological hazards, exposure to fumes and airborne particles, working at noise levels ranging from moderate to loud.
+ The employee regularly works with live animals with risk of exposure to allergens, zoonotic disease, and biohazards.
+ Regularly works with or near test articles with unknown levels of toxicity.
+ The noise level in the work environment ranges from low to high depending upon the species housed.
**About Insourcing Solutions**
Charles River Insourcing Solutionsâ„ can streamline research by delivering operational and cost efficiencies through the strategic insourcing of GMP, GLP and non-GLP research services from discovery through safety assessment. Insourcing Solutionsâ„ provides you with the ability to maintain control of your facility and expertise while leveraging available space.
**About Charles River**
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients' clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.
With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client's unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.
At Charles River, we are passionate about our role in improving the quality of people's lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly worked on 80% of the drugs approved by the U.S. Food and Drug Administration (FDA) in the past five years.
We're committed to providing benefits that elevate your quality of life. Based on your position these may include: bonus/incentives based on performance, 401K, paid time off, stock purchase program, Health and wellness coverage, employee and family wellbeing support programs, and work life balance flexibility.
**Equal Employment Opportunity**
Charles River is an equal opportunity employer and is committed to providing equal employment opportunities for all qualified applicants and employees without regard to race, color, sex, religion, national origin, ancestry, age, mental or physical disability, family status, pregnancy, military or veteran status, or any other characteristic protected by federal, state, or local laws.
It is unlawful in some states (including Massachusetts) to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitment_**********. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.
For more information, please visit ***************
231519
Easy ApplyPost Doctoral Scientist, Synthetic Innovation Technologies
San Diego, CA job
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
Location: San Diego, CA
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
Do you have strong Synthetic Organic Chemistry skills with extensive working knowledge of modern synthetic chemistry methodologies and a passion for at-the-bench impact? If you have demonstrated examples of scientific creativity and the ability to ideate independently and in teams solving problems through hypothesis-based experimental design, apply today!
The Synthetic Innovation Team at Lilly is actively growing with the goal of building a community of scientists with the knowledge and resources to significantly impact all stages of our drug-discovery and development portfolio. The ideal candidate will have strong attention to detail, excellent problem-solving skills, a high level of learning agility, and a willingness to work across teams. We are an innovative and dynamic group looking to enhance our diverse team and capabilities in drug discovery. We are committed to continually improving our abilities to make life better for patients around the globe.
We are looking for someone who can:
Keep safety as the top priority, striving to maintain a strong safety culture
Deliver high laboratory synthetic efficiency to accelerate the design-make-test-analyze cycle through the use of automated reaction screening approaches
Embrace a wide range of technologies, including: photoredox catalysis, flow chemistry, electrochemistry, organocatalysis, enzyme catalysis and laboratory automation
Effectively partner with instrument vendors to trouble-shoot equipment
Collaborate with colleagues specialized in medicinal chemistry, high-throughput automated synthesis, and process development
We will consider a broad range of experiences for our open positions. If working for a company where you feel valued and heard is important, apply today and help us improve the lives of patients around the world.
Basic Qualifications:
PhD in Organic Chemistry or related disciplines with all completed requirements by June 2026 [CR1]
A record of scientific contributions including peer-reviewed publications, presentations, and/or patents [CR2]
Preferred Knowledge, Skills, Abilities, Experiences:
Experience with parallel screening approaches for reaction optimization
Experience optimizing air-sensitive reactions
Experience with analytical methods including LCMS, NMR and GCMS
Experience using ChemDraw, SciFinder and Reaxys
Familiarity with software used for screen design and data visualization (e.g. JMP, TIBCO Spotfire, KNIME)
Excellent English language oral and written communication skills and the ability to engage effectively as a teammate in a multidisciplinary and global environment
Experience or familiarity with biocatalysis, directed evolution, site-directed mutagenesis, and protein purification and characterization.
Experience or familiarity with data science
Experience or familiarity with Python, R, or other coding languages
Experience or familiarity with modern advances in organic electrochemistry
Strong interest in creating and advancing new technologies in predictive data chemistry.
Additional Information:
Physical Demands:
The physical demands of this job are consistent with a lab environment.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
Work Environment:
This position's work environment is in a Laboratory.
The
work
environment
characteristics
described here
are
representative of those an employee encounters while performing the essential functions of this job.
*To perform this job successfully, an individual must be able to perform the role and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( Lilly_Recruiting_**************************) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.
Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women's Network, Working and Living with Disabilities. Learn more about all of our groups.
#WeAreLilly
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (******************************************************** for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.
Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), en Able (for people with disabilities). Learn more about all of our groups.
Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is
$58,000 - $123,200
Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
#WeAreLilly
Auto-ApplySr. Engineer - Lab Automation Software Engineer
San Diego, CA job
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
We are seeking a Lab Automation Software Engineer to join our biotherapeutics discovery automation team at the Lilly Biotechnology Center in San Diego, where you'll architect and implement revolutionary software solutions that transform how we discover life-saving biotherapeutics.
As a Lab Automation Software Engineer, you'll be part of a team building an AI-integrated, closed-loop autonomous discovery ecosystem where AI agents and robotic platforms work together seamlessly - designing experiments, executing protocols autonomously, and learning from results in real-time to accelerate discovery. In this role, you'll work with the latest technologies in artificial intelligence, and laboratory digitalization to build software that bridges the digital and physical automation worlds. Your work in developing interfaces for AI-driven automation and creating data pipelines for autonomous experimentation will directly impact the discovery of innovative medicines.
If you're excited about harnessing AI and automation to solve real-world problems in drug discovery and want to be part of building the lab of the future, we want to hear from you.
You will have the opportunity to:
* Develop software applications that orchestrate complex automated laboratory workflows and closed-loop learning systems.
* Build data pipelines and visualization tools that provide real-time insights into lab operations and experimental outcomes.
* Implement machine learning models for visual inspection systems, predictive maintenance, and process optimization that enhance operational efficiency.
* Contribute to digital lab infrastructure including IoT integrations, digital lab twin models, and telemetry monitoring systems.
* Develop and maintain integrations across multiple automation schedulers, LIMS, and data platforms.
* Support robust software deployment through best DevOps practices and cloud-based solutions.
Basic Qualifications:
* B.S. in Computer Science, Software Engineering, Bioengineering/Engineering with at least 5 years of relevant industry experience.
* M.S. in Computer Science, Software Engineering, Bioengineering/Engineering with at least 2 years of relevant industry experience.
Additional Skills/Preferences:
* Experience in the pharmaceutical industry would be preferred.
* Strong proficiency in Python, SQL, and JavaScript, with working knowledge of some additional programing/scripting languages such C#, VBA, R, C++, MATLAB, Bash.
* Experience with statistical analysis tools (JMP, SAS, R) and business intelligence platforms (Tableau, Power BI, Spotfire) is preferred.
* Knowledge of DevOps practices, including database management systems (DBMS), data warehousing, software development, cloud computing platforms (AWS, Azure), and version control tools (GitHub, GitLab) are beneficial.
* Exposure to lab digitalization technologies (IoT device integration, digital lab twins, automated usage and error reporting telemetry metrics) and/or autonomous lab systems is beneficial.
* Familiarity with lab data platforms including Benchling, LabGuru, PostgreSQL, Genedata, or similar LIMS/ELN systems is a plus.
* Strong problem-solving skills and ability to work cross-functionally with scientific and engineering teams.
* Background in life sciences, pharmaceutical research, or high-throughput screening environments is beneficial.
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (******************************************************** for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.
Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), en Able (for people with disabilities). Learn more about all of our groups.
Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is
$72,000 - $189,200
Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
#WeAreLilly
Auto-ApplyPrincipal Scientist - In-vitro Display
San Diego, CA job
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
The Biotechnology Discovery Research group at Lilly's Biotechnology Center in San Diego discovers medicines that address significant unmet needs by integrating biology with innovative scientific capabilities in protein engineering and computational sciences. We collaborate with colleagues in both the discovery and development organizations, including scientists in therapeutic area biology, biomolecule formulation and developability, ADME, Toxicology, PK/PD, Statistics, Computational Biology and clinical development.
We are seeking a highly motivated and organized scientist to contribute to the discovery and development of biotherapeutics. This individual will be responsible for working in a dynamic team environment and be a contributor to multiple work streams, including in vitro display systems for novel antibody discovery, flow cytometry applications, and recombinant antibody expression and characterization. This position requires hands-on experience with flow cytometry, experience in tissue culture, and an understanding of biochemistry and molecular biology especially pertaining to techniques for protein engineering.
The successful candidate is expected to set up and execute experiments, be detail oriented, skilled at data analysis and troubleshooting and will be accountable for preparing and presenting data at lab meetings with guidance regarding required tasks and expected results.
Key Responsibilities
* Discover, engineer, and optimize antibodies using in vitro display technologies to improve biological function, developability, and immunogenicity profiles
* Use biochemical and functional assays to evaluate antibody-antigen interaction including ELISA, cell binding and signaling assays, Octet or other SPR-based techniques,
* Demonstrate strong expertise in molecular and cellular biology techniques including western blotting, PCR, cell culture, and site-directed mutagenesis.
* Experience with antibody fusions, Fc-fusions, and conjugation to antibodies is highly desirable.
Basic Qualifications
* B.S./M.S. in a relevant field with at least 6+ years industry experience in molecular biology, biochemistry, or protein engineering
* Proven hands-on experience with fundamental biology techniques, including: cell culture, viability assays, transfections, Western blot, affinity assays, image-based assays
* Strong experience in molecular biology including standard cloning techniques, sequence analysis, DNA and RNA extraction, ligation, PCR.
Additional Skills and Preferences
* Experience with flow cytometry is highly desirable
* An understanding of antibody discovery, particularly with respect to in vitro display systems
* Excellent communication skills with a desire to be involved in collaborative, cross
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (******************************************************** for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.
Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), en Able (for people with disabilities). Learn more about all of our groups.
Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is
$110,250 - $187,000
Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
#WeAreLilly
Auto-ApplyAdvisor / Sr. Advisor - Peptide Phage Display (San Diego, CA)
San Diego, CA job
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
This is a technical lead position in the Peptide Discovery Team within Biotechnology Discovery Research in San Diego that utilizes multiple peptide discovery platforms to identify functionally active peptides for a given biological target of interest. The individual will spearhead the design and execution of the next generation of peptide phage display (cloning and screening with multicyclic peptide scaffolds) through individual contribution, providing training and working closely with a team of scientists.
This individual will lead the peptide phage display screening projects and collaborate with cross-functional teams to accelerate the development of cyclic peptide hits for therapeutic applications, including peptide drug (small molecule or nucleic acids) conjugates and peptide radionuclide conjugates. Responsibilities for this role include mentoring junior scientists and effectively communicating progress to cross-functional partners within Biotechnology Discovery Research and across Discovery Chemistry, Genetic Medicines, Therapeutic Area Teams, Drug Disposition, Bioproduct Development and Regulatory Affairs.
KEY OBJECTIVES/DELIVERABLES:
* Apply expertise of molecular biology, genetic engineering, and chemistry to build a robust multicyclic peptide phage display platform.
* Execute the multicyclic peptide phage display platform for the discovery and optimization of peptide hits for a given biological target of interest.
* Develop new methods and technologies to strengthen the platform.
* Train junior scientists on the build and execution of multicyclic peptide phage display platform.
* Lead screening projects and collaborate closely with experts in different fields, such as organic chemistry, computational science, and structural biology.
* Incorporate knowledge to improve peptide properties such as binding affinity to target or physicochemical properties.
* In collaboration with peptide chemists, implement rational SAR strategies to improve pharmaceutical properties of therapeutic peptide leads.
* The candidate is expected to exhibit strong problem-solving abilities and be familiar with understanding and resolving issues that lie at the interface of peptide discovery, peptide engineering, pharmaceutical developability and formulation, and biology.
Basic Qualifications:
* A Ph.D. degree in chemistry, biochemistry, or molecular biology with a strong focus on peptides.
* 2+ years of experience in a biotechnology/pharmaceutical company with a demonstrated leadership in peptide discovery and a track record of advancing peptide-based therapeutics, from concept to clinical development.
Additional Skills and Preferences:
* Supervisory experience in directing junior scientists in the design and execution of experiments.
* Experience using state-of-the-art peptide phage display peptide platform as demonstrated by publications or patents.
* Experience with biochemical and cell assay design and development to support peptide discovery efforts.
* Experience in triaging and validating peptide actives following selection campaigns
* Understanding compound physical chemistry models, measurements, their relationships to ADME properties.
* Appreciation of peptide formulation requirements and experience incorporating pharmaceutical developability assessment in peptide optimization.
* Demonstrated ability to work cross-functionally, and excellent organizational, communication and presentation skills.
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (******************************************************** for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.
Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), en Able (for people with disabilities). Learn more about all of our groups.
Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is
$133,500 - $217,800
Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
#WeAreLilly
Auto-ApplyAnimal Care Technician II
Charles River Laboratories job in San Diego, CA
For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we'll help you build a career that you can feel passionate about.
**Job Summary**
We are seeking an Animal Care Technician II to join our Insourcing Solutions team, located in San Diego, CA.
As the Animal Care Technician II, you will perform animal care and husbandry duties on rodent species in accordance with AAALAC standards and client's SOPs/policies. Observe, monitor, and document the health and physical environment within the client's animal facility. Perform a variety of technical procedures on research rodents.
Additional responsibilities include:
+ Review, comprehend and comply with all SOPs, guidelines/policies, training provided both verbally and written, protocols, and quality assurance standards pertaining to assigned responsibilities and to the care and use of laboratory animals for research.
+ Monitor daily animal health and welfare while performing daily animal health observations utilizing an assigned iPAD or tablet device.
+ Perform animal husbandry duties to maintain quality and health of research animals, to include: perform daily water bottle / automatic water line and cage checks; provide appropriate food and water; perform cage changing and/or cage cleaning as required; record animal health concerns per SOP and/or specified protocols.
+ Maintain accurate room maintenance records and other required record-keeping documentation as required by department SOPs and/or guidelines/policies.
+ Work closely with client's Veterinarians and Veterinary Staff, assist with animal sample collection and other _in vivo_ procedures as assigned by the on-site facility veterinarian or veterinary staff member.
+ Provide service daily to the researchers to ensure study animals receive medicated diet and/or medicated water and any other special housing requests outlined in their study protocol. Direct communication and interaction may be required between employee and researcher.
**Responsibilities continued**
+ Perform a variety of technical procedures on rodents, such as, ear tagging, shaving, blood collection, tissue sampling, etc.
+ Strictly follow all procedures necessary to maintain animal housing areas or isolator environments, including room or facility personnel entry and personal protective equipment use, biosecurity procedures, and safety procedures.
+ Receive, inspect, and house incoming animals; care for and provide for sentinel-free soiled bedding collection cages in each rodent housing area as required by department SOPs, guidelines/policies, and protocols.
+ Operate equipment and use supplies according to safety guidelines; perform general housekeeping and adheres to safety procedures.
+ Maintain required attendance level and adherence to assigned work schedule in accordance with required staffing levels in order to ensure that assigned duties are completed to client standards.
+ Assists with the receipt, stocking inventory, and maintenance of supplies.
+ Perform all other related duties as assigned.
**Job Qualifications**
+ To qualify for this role, candidates must have one of the following combinations of education/experience:
+ HS/GED and 1 year directly related lab animal experience.
+ AA/AS and 6 months directly related lab animal experience.
+ BA/BS in animal or life sciences, no experience required.
+ Certification/Licensure: AALAS certification at the ALAT level preferred
+ Schedule will be 6:00 a.m. - 2:30 p.m., Sunday - Thursday or Tuesday - Saturday
The pay range for this position is $27-29 USD per hour. Please note that salaries vary within the range based on factors including skills, certifications, and location.
Knowledge, Skills and Abilities
+ Proficiency with basic animal identification and handling methods.
+ Ability to effectively follow verbal and written instructions and exhibit interpersonal skills that are conducive to effective communication and that contribute to a congenial work environment. Maintain a positive work atmosphere by behaving and communicating in a professional manner with coworkers, research staff, and management.
+ Strong organization skills and attention to detail. Strong written and verbal English communication skills. Proficiency with computers and software documentation systems, including good working knowledge of Microsoft Word and Excel.
**Physical Demands**
+ While performing the duties of this job, the employee is regularly required to stand, use hands and fingers to handle, feel, or use objects, tools, or controls, and reach with hands and arms. The employee is frequently required to walk, stoop, kneel, crouch, or crawl. The employee is occasionally required to sit. The employee is frequently required to type at a computer or tablet/iPAD. The employee must regularly lift and/or move up to 50 pounds. Occasionally lift and/or move up to 100 pounds.
+ Specific vision abilities required by this job include close vision, distance vision, peripheral vision, depth perception, and the ability to adjust focus. The employee is regularly required to talk and/or hear.
Work Environment
+ While performing the duties of this job, the employee frequently works near or with moving mechanical parts and robotics and is frequently exposed to laboratory animals and caging of various species including mice, rats, and other small animals. The employee is frequently exposed to wet and/or humid conditions, fumes or airborne particles, toxic or caustic chemicals, animal allergens, biohazard materials and risk of electrical shock. The noise level in the work environment is usually loud and may require hearing protection.
**About Insourcing Solutions**
Charles River Insourcing Solutionsâ„ can streamline research by delivering operational and cost efficiencies through the strategic insourcing of GMP, GLP and non-GLP research services from discovery through safety assessment. Insourcing Solutionsâ„ provides you with the ability to maintain control of your facility and expertise while leveraging available space.
**About Charles River**
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients' clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.
With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client's unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.
At Charles River, we are passionate about our role in improving the quality of people's lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly worked on 80% of the drugs approved by the U.S. Food and Drug Administration (FDA) in the past five years.
We're committed to providing benefits that elevate your quality of life. Based on your position these may include: bonus/incentives based on performance, 401K, paid time off, stock purchase program, Health and wellness coverage, employee and family wellbeing support programs, and work life balance flexibility.
**Equal Employment Opportunity**
Charles River is an equal opportunity employer and is committed to providing equal employment opportunities for all qualified applicants and employees without regard to race, color, sex, religion, national origin, ancestry, age, mental or physical disability, family status, pregnancy, military or veteran status, or any other characteristic protected by federal, state, or local laws.
It is unlawful in some states (including Massachusetts) to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitment_**********. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.
For more information, please visit ***************
231522
Easy ApplyAdvisor - Lab Automation Scientist
San Diego, CA job
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
Join us at the forefront of AI-driven drug discovery!
The Biologics Automation and High-throughput Technologies Group at the Lilly Biotechnology Center in San Diego is seeking a Senior Lab Automation Scientist to revolutionize early-stage discovery and screening of protein therapeutics. We're building the future of biotherapeutics research by creating lab-in-the-loop systems that seamlessly integrate AI agents with physical automation, closing the discovery-to-data cycle in unprecedented ways.
The ideal candidate will have hands-on experience with advanced lab automation equipment, laboratory software, and data analysis tools. As a key member of our team, you'll harness the latest technologies in automation equipment and artificial intelligence to transform how we discover and develop life-changing medicines. You'll work at the intersection of biology, data science, and robotics-designing intelligent, adaptive workflows where AI-powered decision-making drives autonomous laboratory operations in real time.
Job Responsibilities:
* Ensure that common lab automation equipment commonly used in biotherapeutic discovery labs is maintained in good working order. This includes stand-alone liquid handlers/micro-dispensers, plate readers/washers, protein quantification instruments, colony/plaque pickers, sequencing instruments etc., as well as several fully integrated robotic systems.
* Work closely with automation engineers on the team who are currently responsible for installing, maintaining, and qualifying automation equipment, developing operational scripts, updating scheduling software, and providing support to non-automation scientists throughout the site.
* Work collaboratively with protein discovery, engineering, and protein expression groups at the San Diego site to optimize research efficiencies through implementation of novel automation process improvements and technologies.
* Collaborate with both external vendors and internal teams to design, implement, and validate new automation equipment, integrated robotic workstations, lab digitalization technologies, as well as autonomous laboratory automation systems and closed-loop learning solutions.
Minimum qualifications:
* Ph.D. in Bioengineering, Biomedical Engineering, Chemical Engineering, Mechanical Engineering or related discipline with at least 2 years of industry experience (following post-doctorate), or
* M.S. in Bioengineering, Biomedical Engineering, Chemical Engineering, Mechanical Engineering or related discipline with a minimum of 10 years of automation engineer-specific experience, or
* B.S. in Bioengineering, Biomedical Engineering, Chemical Engineering, Mechanical Engineering or related discipline with a minimum of 13 years of automation engineer-specific experience
* Experience should include relevant industry experience, in a well-equipped automation lab, preferably in a pharmaceutical company or an automation provider.
Other preferred key attributes and skills
* Proficiency in the operation, maintenance, troubleshooting and optimization of liquid handlers (Beckman, Hamilton, HighRes, Lynx etc.), micro-dispensers (BioTek, Themo, Formulatrix, etc.) microplate washers and readers, high throughput antibody quantification instruments and E. coli colony plating/picking (QPix) is a must.
* Hands-on expertise in the operation, maintenance, troubleshooting and optimization of integrated automation workstations including schedulers such as SAMI, Green Button Go, Cellario, Director, Retisoft Genera or Agilent VWorks is required.
* Programming experience using Python, Java, C#, Visual Basic, or SQL is as asset.
* Experience with statistical analysis tools (JMP, SAS, R) and business intelligence platforms (Tableau, Power BI, Spotfire) is preferred.
* Familiarity with lab data platforms including Benchling, LabGuru, PostgreSQL, Genedata, or similar LIMS/ELN systems.
* Previous experience in the direct supervision of lab automation engineers in an industry setting is required.
* Excellent organizational skills, as exemplified by an aptitude for clear record-keeping, and data analysis, and the ability to prioritize work across multiple projects.
* Demonstrated ability to collaborate with automation engineer colleagues and scientists to design, validate and implement automated workflows for complex biological discovery workflows.
* Demonstrated aptitude in technical training and support of laboratory staff on lab automation equipment and integrated workstations.
* Proven skill in process development initiatives and continuous optimization of automation-driven discovery workflows.
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (******************************************************** for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.
Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), en Able (for people with disabilities). Learn more about all of our groups.
Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is
$138,000 - $224,400
Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
#WeAreLilly
Auto-ApplySenior Principal Scientist / Associate Director, Lead Scientific Data Governance
San Diego, CA job
In this role, you will spearhead strategic data governance projects to maximize the value of our scientific data assets, ensuring they are structured, interoperable, and ready for advanced analytics and AI applications. Working closely with scientific teams and IT partners, you will translate complex scientific workflows into scalable, efficient data solutions. Success in this position requires strong communication and project management skills, broad expertise in drug discovery, and the ability to operate effectively within large, matrixed organizations. You will play a pivotal role in shaping how data is leveraged across scientific domains to accelerate drug discovery and enable enterprise-wide innovation.
Job Description
Internal Job Title: Sr. Principal Scientist, Data Science/Associate Director, Data Science
Position Location: onsite, San Diego, CA
#LI-Onsite
Are you ready to unlock the power of scientific data assets and advance data‑driven innovation in drug discovery? Join us at Novartis BioMedical Research as a member of the Discovery Sciences (DSc) Data Excellence team and help shape the future of scientific data governance.
In this role, you will spearhead strategic data governance projects to maximize the value of our scientific data assets, ensuring they are structured, interoperable, and ready for advanced analytics and AI applications. Working closely with scientific teams and IT partners, you will translate complex scientific workflows into scalable, efficient data solutions. Success in this position requires strong communication and project management skills, broad expertise in drug discovery, and the ability to operate effectively within large, matrixed organizations. You will play a pivotal role in shaping how data is leveraged across scientific domains to accelerate drug discovery and enable enterprise-wide innovation.
Key Responsibilities
Lead the execution of data governance projects across DSc scientific data domains.
Guide cross-functional teams to define and implement robust data standards, establish metadata requirements, and develop effective stewardship practices.
Ensure scientific data is captured with rich contextual metadata to enable reuse and interoperability across platforms.
Facilitate the harmonization of scientific workflows and data products by partnering with matrixed teams across the organization.
Serve as the business owner of key scientific data applications and work with IT product teams to ensure tailored implementation and support.
Promote data literacy and drive adoption of data governance frameworks.
Represent DSc on cross-functional data governance boards and contribute to the enterprise data strategy.
Essential Requirements
Advanced degree (Ph.D. or M.Sc.) in life sciences, data science, or a related field.
8+ years of experience in pharmaceutical R&D, with proven track record of working with diverse scientific data types (e.g., omics, imaging, screening).
Proven experience in data management and stewardship, with a focus on enabling harmonization and integration of diverse data assets across multiple systems.
Track record of successfully leading cross-functional initiatives in complex, matrixed organizations.
Excellent project management and stakeholder engagement skills.
Demonstrated ability to translate complex scientific workflows and technical requirements into scalable data solutions.
Demonstrated ability to communicate data strategy insights and recommendations to cross-functional stakeholders.
Desirable Requirements
Experience with database management systems and working knowledge of coding languages commonly used in scientific data workflows (e.g., SQL, Python, R).
Advanced expertise in FAIR principles, metadata standards, and enterprise data platforms
Specialized knowledge of data governance frameworks and data quality metrics within a drug discovery context.
The salary for this position is expected to range between: Sr. Principal Scientist, Data Science: $160,300 and $297,700 per year, and Associate Director, Data Science: $176,400 and $327,600 per year. The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors.
Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.
US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days,
holidays and other leaves.
To learn more about the culture, rewards and benefits we offer our people click here.
EEO Statement:
The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.
Accessibility and reasonable accommodations
The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to us.reasonableaccommodations@novartis.com or call *************** and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
Salary Range
$160,300.00 - $297,700.00
Skills Desired
Apache Spark, Artificial Intelligence (AI), Big Data, Data Governance, Data Literacy, Data Management, Data Quality, Data Science, Data Strategy, Data Visualization, Machine Learning (Ml), Master Data Management, Python (Programming Language), R (Programming Language), Statistical Analysis
Auto-ApplyAnimal Care Technician I
Charles River Laboratories job in San Diego, CA
For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we'll help you build a career that you can feel passionate about.
Job Summary
We are seeking an Animal Care Technician I to join our Insourcing Solutions team, located in San Diego, CA.
As the Animal Care Technician I, you will maintain, monitor and document the health, production, and physical environment within the customer's varied animal care facilities.
Additional responsibilities include:
* Reviews, comprehends and complies with all SOP's and quality assurance standards pertaining to specific area.
* Monitors daily animal health and welfare while performing daily animal health observations, animal husbandry duties to maintain quality and health of research animals, to include: perform daily water bottle /automatic water line and cage checks; provide appropriate food and water; perform cage changing and/or cage cleaning as required; record animal health concerns per SOP and/or specified protocols.
* Maintains accurate records of animal breeding, health, and housing/isolator or support areas as required by Institute and facility.
* Assists with restraint, handling and manipulation of various animal species as assigned by the on-site Supervisor or facility veterinarian.
* Strictly follows all procedures necessary to maintain animal housing areas or semi-rigid isolator environments, including room or facility personnel entry; personnel protective equipment use, spraying in all equipment and materials into controlled areas.
* Receives, inspects and puts away incoming animals; ensures and provides for sentinel animals in each rodent housing area.
* May be involved in strictly maintaining and following breeding and weaning procedures to ensure appropriate production levels.
* Operates equipment and uses supplies according to safety guidelines; performs general housekeeping and adheres to safety procedures.
* Maintains required attendance level and adherence to work schedule in accordance with required staffing levels in order to ensure that assigned duties are completed.
* Performs other duties as assigned.
Job Qualifications
Education & Experience: To qualify for this role, candidates must have one of the following combinations of education/experience:
* High School Diploma or G.E.D. plus a minimum of six to twelve months experience working in a laboratory animal facility performing animal husbandry
* Associates degree in animal science or related field plus a minimum of six months experience working in a laboratory animal facility performing animal husbandry.
* Bachelors degree in animal science or related field plus zero to six months experience working in laboratory animal facility performing animal husbandry.
The pay range for this position is $22-23.50 USD per hour. Please note that salaries vary within the range based on factors including skills, certifications, and location.
If you are interested in contributing to the well-being of our communities, not only across the country but around the world, please join us and BE THE DIFFERENCE!
Additional Information:
Knowledge, Skills and Abilities:
* Must be able to follow verbal and written instructions and exhibit interpersonal skills that are conducive to effective communication and that contribute to a congenial work environment. Maintain positive work atmosphere by behaving and communicating in a professional manner with clients, customers, coworkers, and supervisors.
* Ability to read, write, speak and understand high school level English.
* Computer literacy using timekeeping, training software and word processing required; database record keeping helpful.
Physical Demands:
* While performing the duties of this job, the employee is regularly required to stand; use hands to finger, handle, or feel objects, tools, or controls; and reach with hands and arms. The employee frequently is required to walk and stoop, kneel, crouch, or crawl. The employee is occasionally required to sit.
* The employee must regularly lift and/or move up to 50 pounds and occasionally lift/move up to 100 pounds.
* Specific vision abilities required by this job include close vision, distance vision, peripheral vision, depth perception, and the ability to adjust focus.
Work Environment:
* While performing the duties of this job, the employee frequently works near moving mechanical parts; is exposed to fumes or airborne particles, laboratory animal caging of various species including mice, rats, and other rodents and possibly rabbits and is occasionally exposed to wet and/or humid conditions, toxic or caustic chemicals, biohazard materials/agents, infectious disease and risk of electrical shock.
* The noise level in the work environment is usually moderate.
About Insourcing Solutions
Charles River Insourcing Solutionsâ„ can streamline research by delivering operational and cost efficiencies through the strategic insourcing of GMP, GLP and non-GLP research services from discovery through safety assessment. Insourcing Solutionsâ„ provides you with the ability to maintain control of your facility and expertise while leveraging available space.
About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients' clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.
With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client's unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.
At Charles River, we are passionate about our role in improving the quality of people's lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly worked on 80% of the drugs approved by the U.S. Food and Drug Administration (FDA) in the past five years.
We're committed to providing benefits that elevate your quality of life. Based on your position these may include: bonus/incentives based on performance, 401K, paid time off, stock purchase program, Health and wellness coverage, employee and family wellbeing support programs, and work life balance flexibility.
Equal Employment Opportunity
Charles River is an equal opportunity employer and is committed to providing equal employment opportunities for all qualified applicants and employees without regard to race, color, sex, religion, national origin, ancestry, age, mental or physical disability, family status, pregnancy, military or veteran status, or any other characteristic protected by federal, state, or local laws.
It is unlawful in some states (including Massachusetts) to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitment_**********. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.
For more information, please visit ***************
231328
Easy ApplyPost Doctoral Scientist, Synthetic Innovation Technologies
San Diego, CA job
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
Location: San Diego, CA
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
Do you have strong Synthetic Organic Chemistry skills with extensive working knowledge of modern synthetic chemistry methodologies and a passion for at-the-bench impact? If you have demonstrated examples of scientific creativity and the ability to ideate independently and in teams solving problems through hypothesis-based experimental design, apply today!
The Synthetic Innovation Team at Lilly is actively growing with the goal of building a community of scientists with the knowledge and resources to significantly impact all stages of our drug-discovery and development portfolio. The ideal candidate will have strong attention to detail, excellent problem-solving skills, a high level of learning agility, and a willingness to work across teams. We are an innovative and dynamic group looking to enhance our diverse team and capabilities in drug discovery. We are committed to continually improving our abilities to make life better for patients around the globe.
We are looking for someone who can:
* Keep safety as the top priority, striving to maintain a strong safety culture
* Deliver high laboratory synthetic efficiency to accelerate the design-make-test-analyze cycle through the use of automated reaction screening approaches
* Embrace a wide range of technologies, including: photoredox catalysis, flow chemistry, electrochemistry, organocatalysis, enzyme catalysis and laboratory automation
* Effectively partner with instrument vendors to trouble-shoot equipment
* Collaborate with colleagues specialized in medicinal chemistry, high-throughput automated synthesis, and process development
*
We will consider a broad range of experiences for our open positions. If working for a company where you feel valued and heard is important, apply today and help us improve the lives of patients around the world.
Basic Qualifications:
* PhD in Organic Chemistry or related disciplines with all completed requirements by June 2026 [CR1]
* A record of scientific contributions including peer-reviewed publications, presentations, and/or patents [CR2]
Preferred Knowledge, Skills, Abilities, Experiences:
* Experience with parallel screening approaches for reaction optimization
* Experience optimizing air-sensitive reactions
* Experience with analytical methods including LCMS, NMR and GCMS
* Experience using ChemDraw, SciFinder and Reaxys
* Familiarity with software used for screen design and data visualization (e.g. JMP, TIBCO Spotfire, KNIME)
* Excellent English language oral and written communication skills and the ability to engage effectively as a teammate in a multidisciplinary and global environment
* Experience or familiarity with biocatalysis, directed evolution, site-directed mutagenesis, and protein purification and characterization.
* Experience or familiarity with data science
* Experience or familiarity with Python, R, or other coding languages
* Experience or familiarity with modern advances in organic electrochemistry
* Strong interest in creating and advancing new technologies in predictive data chemistry.
Additional Information:
Physical Demands:
The physical demands of this job are consistent with a lab environment.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
Work Environment:
This position's work environment is in a Laboratory.
The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job.
* To perform this job successfully, an individual must be able to perform the role and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively "Lilly") are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( Lilly_Recruiting_**************************) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.
Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women's Network, Working and Living with Disabilities. Learn more about all of our groups.
#WeAreLilly
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (******************************************************** for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.
Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), en Able (for people with disabilities). Learn more about all of our groups.
Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is
$58,000 - $123,200
Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
#WeAreLilly
Auto-ApplySr. Scientist
San Diego, CA job
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
Responsibilities
The scientist will be an integral part of the immunology team and will provide flow cytometry and immunology expertise to support the portfolio. Primary responsibilities include guiding users on appropriate instrumentation, training users on acquisition and analysis, and generating data that drives project decisions.
Representative Key Responsibilities Include
Flow cytometry expertise including spectral flow
Lead flow cytometry training and data QC to new and existing users
Design flow panels in coordination with project scientists
Convey core capabilities to lead scientists in-order-to provide flow and imaging solutions to meet projects needs
Collaborate across Lilly research sites and share key learnings and best practices
Keep up-to-date with emerging technologies and evaluate them in-house when appropriate
Basic Qualifications
Education:
Bachelor's degree in Biological Science or related field with a minimum of 5 years research experience with spectral flow cytometry, and deep immunology expertise.
Master's degree in Biological Science or related field with a minimum of 3 years' experience with spectral flow cytometry, and deep immunology expertise.
Additional Skills/Preferences
Experience with imaging flow cytometers
Experience with high content imagers, confocal microscopes, and fluorescent slide scanners
Demonstrated ability to work effectively both independently and as team
Good communication skills including presenting results in team meetings
Excellent problem-solving skills and ability to effectively prioritize multiple tasks and projects
Strong self-start and self-management skills
Qualified applicants must be authorized to work in the United States on a full-time basis. Lilly will not provide support for or sponsor work authorization and/or visas for this role
Additional Information
Travel: 5-10%
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (******************************************************** for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.
Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), en Able (for people with disabilities). Learn more about all of our groups.
Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is
$71,250 - $187,000
Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
#WeAreLilly
Auto-ApplyPost-Doctoral Scientist, Immunology
San Diego, CA job
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
JOB SUMMARY
We are seeking an ambitious and talented post-doctoral scientist with exceptional communication skills to study the function of Tregs in the pathogenesis of autoimmune diseases. In this role, you will join our academic-style post-doctoral program and will be encouraged to pursue your own independent research while learning about industry drug discovery and development. You will be responsible for designing and delivering highly innovative research and will have access to all cutting-edge technologies available at Lilly.
RESPONSIBILITIES
You will:
Study Treg function in tissues at different stages of autoimmune diseases.
Design and execute experiments to test hypotheses related to disease mechanisms.
Conduct literature searches and review relevant scientific literature to inform research strategy and identify emerging trends in the field of Tregs.
Develop and deliver effective communications for technical and non-technical audiences; prepare and present scientific reports and publications.
Collaborate effectively with colleagues at all levels to advance project goals.
Apply advanced scientific knowledge to develop creative solutions to complex problems.
Plan and schedule work independently, prioritize tasks, and manage time effectively.
BASIC QUALIFICATIONS
PhD in Immunology completed by October/November 2025.
Strong background in the study of immune cells.
ADDITIONAL SKILLS/PREFERENCES
Self-directed and highly motivated scientist who wants to learn new techniques while pursuing research and publication goals.
Strong experience in cellular immunology, flow cytometry, and mouse in vivo models. Experience working with Tregs a plus.
Exceptional communicator (oral and written) with a strong publication record.
Proficient in data analysis and reporting (PRISM, Excel, Powerpoint, FlowJo).
ADDITIONAL INFORMATION
This position is not permanent. It is for a fixed duration of three years with potential to extend once for up to 4 years.
Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (******************************************************** for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.
Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), en Able (for people with disabilities). Learn more about all of our groups.
Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is
$58,000 - $100,320
Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
#WeAreLilly
Auto-Apply