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The Clinical Applications Specialist serves as a crucial link between healthcare technology and medical professionals, ensuring that clinical applications are effectively utilized. As of October 2025, the average salary for this position is $82,143 per year, translating to approximately $39 per hour. This salary can vary based on several factors, including geographical location, years of experience, and the specific healthcare setting.
States such as California and Massachusetts consistently offer higher salaries for Clinical Applications Specialists, reflecting the demand for skilled professionals in these regions. For instance, the highest-paying states can see annual salaries exceeding $95,000. Meanwhile, entry-level positions typically start around $60,000, with potential for significant increases as experience grows.
The demand for Clinical Applications Specialists is projected to remain strong due to ongoing advancements in healthcare technology. As facilities adopt new systems, the need for specialists who can train staff and ensure smooth transitions becomes increasingly essential. If you're considering a career in this field, explore job openings that match your skills and experience to find the right opportunity.
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The average clinical applications specialist salary in Hawaii, Washington, and Alaska are the highest in the U.S. The lowest average clinical applications specialist salary states are Virginia, Colorado, and Florida.
| Rank | State | Avg. salary | Hourly rate |
|---|---|---|---|
| 1 | Montana | $93,878 | $45.13 |
| 2 | Arizona | $94,859 | $45.61 |
| 3 | North Dakota | $91,955 | $44.21 |
| 4 | Hawaii | $107,557 | $51.71 |
| 5 | Washington | $98,451 | $47.33 |
| 6 | Louisiana | $92,639 | $44.54 |
| 7 | Utah | $93,721 | $45.06 |
| 8 | South Dakota | $90,481 | $43.50 |
| 9 | Maine | $85,784 | $41.24 |
| 10 | Ohio | $91,874 | $44.17 |
| 11 | Maryland | $94,034 | $45.21 |
| 12 | Idaho | $93,200 | $44.81 |
| 13 | Indiana | $87,794 | $42.21 |
| 14 | North Carolina | $83,993 | $40.38 |
| 15 | Alaska | $95,662 | $45.99 |
| 16 | South Carolina | $90,710 | $43.61 |
| 17 | Oregon | $86,630 | $41.65 |
| 18 | Nebraska | $84,202 | $40.48 |
| 19 | Nevada | $84,787 | $40.76 |
| 20 | California | $86,766 | $41.71 |
| 21 | Minnesota | $84,508 | $40.63 |
| 22 | Wyoming | $83,133 | $39.97 |
| 23 | Missouri | $84,062 | $40.41 |
| 24 | Mississippi | $85,342 | $41.03 |
| 25 | Kansas | $81,674 | $39.27 |
| 26 | New York | $81,821 | $39.34 |
| 27 | New Jersey | $81,769 | $39.31 |
| 28 | Massachusetts | $88,923 | $42.75 |
| 29 | Michigan | $81,475 | $39.17 |
| 30 | Pennsylvania | $79,977 | $38.45 |
| 31 | Illinois | $82,947 | $39.88 |
| 32 | Connecticut | $79,842 | $38.39 |
| 33 | District of Columbia | $80,187 | $38.55 |
| 34 | Rhode Island | $79,102 | $38.03 |
| 35 | Tennessee | $79,710 | $38.32 |
| 36 | Delaware | $80,397 | $38.65 |
| 37 | Oklahoma | $79,894 | $38.41 |
| 38 | Wisconsin | $79,267 | $38.11 |
| 39 | West Virginia | $78,554 | $37.77 |
| 40 | Georgia | $80,072 | $38.50 |
| 41 | Vermont | $76,467 | $36.76 |
| 42 | Florida | $71,753 | $34.50 |
| 43 | Kentucky | $76,528 | $36.79 |
| 44 | Iowa | $71,417 | $34.34 |
| 45 | Texas | $76,319 | $36.69 |
| 46 | New Mexico | $70,265 | $33.78 |
| 47 | Alabama | $75,140 | $36.13 |
| 48 | New Hampshire | $77,549 | $37.28 |
| 49 | Colorado | $73,861 | $35.51 |
| 50 | Virginia | $74,363 | $35.75 |
| 51 | Arkansas | $66,273 | $31.86 |
The highest-paying cities for clinical applications specialists are Bothell, WA, Baltimore, MD, and San Francisco, CA.
| Rank | City | Avg. salary | Hourly rate |
|---|---|---|---|
| 1 | Bothell, WA | $99,179 | $47.68 |
| 2 | Baltimore, MD | $94,119 | $45.25 |
| 3 | San Francisco, CA | $90,680 | $43.60 |
| 4 | Amherst, MA | $89,453 | $43.01 |
| 5 | Saint Louis, MO | $84,120 | $40.44 |
| 6 | Charlotte, NC | $83,261 | $40.03 |
| 7 | North Chicago, IL | $83,258 | $40.03 |
| 8 | New York, NY | $81,950 | $39.40 |
| 9 | Jersey City, NJ | $81,756 | $39.31 |
| 10 | Washington, DC | $80,175 | $38.55 |
| 11 | Waukesha, WI | $79,259 | $38.11 |
| 12 | Dover, NH | $76,916 | $36.98 |
| 13 | Grand Prairie, TX | $75,768 | $36.43 |
| 14 | Chesapeake, VA | $74,463 | $35.80 |
| 15 | Denver, CO | $73,866 | $35.51 |
A clinical applications specialist's salary ranges from $63,000 a year at the 10th percentile to $106,000 at the 90th percentile.

| Percentile | Annual salary | Monthly salary | Hourly rate |
|---|---|---|---|
| 90th Percentile | $106,000 | $8,833 | $51 |
| 75th Percentile | $94,000 | $7,833 | $45 |
| Average | $82,143 | $6,845 | $39 |
| 25th Percentile | $71,000 | $5,917 | $34 |
| 10th Percentile | $63,000 | $5,250 | $30 |
The highest paying types of clinical applications specialists are clinical informatics strategist, director of informatics, and nurse informaticist.
| Job title | Annual salary | Monthly salary | Hourly rate | Job openings |
|---|---|---|---|---|
| Director Of Informatics | $113,003 | $9,417 | $54.33 | 6,305 |
| Epic Consultant | $89,651 | $7,471 | $43.10 | 9,050 |
| Applications Coordinator | $55,838 | $4,653 | $26.85 | 21,445 |
| Clinical Analyst | $80,252 | $6,688 | $38.58 | 101,209 |
Top companies hiring clinical applications specialists now:
Clinical applications specialist salaries at Children's Hospital Colorado and Varian Medical Systems are the highest-paying according to our most recent salary estimates. In addition, the average clinical applications specialist salary at companies like Sysmex and Randstad North America, Inc. are highly competitive.
| Rank | Company | Average salary | Hourly rate |
|---|---|---|---|
| 1 | Children's Hospital Colorado | $97,411 | $46.83 |
| 2 | Varian Medical Systems | $95,947 | $46.13 |
| 3 | Sysmex | $95,905 | $46.11 |
| 4 | Randstad North America, Inc. | $93,692 | $45.04 |
| 5 | Waters | $93,421 | $44.91 |
| 6 | Oculus | $93,253 | $44.83 |
| 7 | FUJIFILM Diosynth Biotechnologies | $92,935 | $44.68 |
| 8 | Atrium Health Floyd | $91,994 | $44.23 |
| 9 | MemorialCare | $89,986 | $43.26 |
| 10 | Millennium Physician Group | $89,848 | $43.20 |
| 11 | FUJIFILM Medical Systems USA | $89,786 | $43.17 |
| 12 | Cedars-Sinai | $88,736 | $42.66 |
| 13 | Samsung Electronics Device Solutions (Semiconductor & Display) | $88,375 | $42.49 |
| 14 | Green Key Resources | $87,969 | $42.29 |
| 15 | La Rabida Children's Hospital | $87,781 | $42.20 |
| 16 | Integrated Resources | $87,773 | $42.20 |
| 17 | VIVA USA | $87,142 | $41.90 |
| 18 | Alcon | $86,226 | $41.45 |
| 19 | Philips | $86,122 | $41.40 |
| 20 | Yale New Haven Health | $86,071 | $41.38 |
The average clinical applications specialist salary has risen by $13,228 over the last ten years. In 2014, the average clinical applications specialist earned $68,915 annually, but today, they earn $82,143 a year. That works out to a 8% change in pay for clinical applications specialists over the last decade.
Compare clinical applications specialist salaries for cities or states with the national average over time.
Compare clinical applications specialist salaries for individual cities or states with the national average.
| Year | Avg. salary | Hourly rate | % Change |
|---|---|---|---|
| 2025 | $82,100 | $39.49 | +3.3% |
| 2024 | $79,400 | $38.19 | +2.3% |
| 2023 | $77,600 | $37.33 | +0.5% |
| 2022 | $77,200 | $37.13 | +1.2% |
| 2021 | $76,300 | $36.69 | +1.6% |
| Company | Job | Location | Date added | Salary |
|---|---|---|---|---|
| Searhc | IT RN Clinical Application Specialist-Intermittent | Juneau, AK | 06/29/2025 | $86,944 |
| GE Healthcare | CT Clinical Applications Specialist-Western US | Madison, WI | 06/26/2025 | $89,600 |
| GE Healthcare | CT Clinical Applications Specialist-Western US | Des Moines, IA | 06/26/2025 | $89,600 |
| GE Healthcare | CT Clinical Applications Specialist-Western US | Lincoln, NE | 06/26/2025 | $89,600 |
| GE Healthcare | CT Clinical Applications Specialist-Western US | Indianapolis, IN | 06/26/2025 | $89,600 |
| GE Healthcare | Clinical Applications Specialist, MIC, Nicu | Denver, CO | 06/21/2025 | $89,600 |
| Sysmex America | Specialist I, Clinical Applications | Downe, NJ | 06/21/2025 | $60,200 |
| Harriscomputer | Clinical Application Specialist | Kane, IL | 06/20/2025 | $75,000 |
| Heritage Behavioral Health Center, Inc. | IT Clinical Applications Specialist | Decatur, IL | 06/16/2025 | $70,000 |
| GE Healthcare | Clinical Applications Specialist | Chicago, IL | 06/04/2025 | $115,200 |
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