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Best start-up companies in Missouri

We hand-curated a list of the best start-up companies to work in Missouri using data on salaries, company financial health, and employee diversity. You can also search for the best companies to work for in the state and cities you want.

Best companies to work for in Missouri
  1. Zippia score 4.7

    #1 Best start-up company to work for in Missouri
    Company description:

    Cassidy Turley was a privately owned commercial real estate services firm. Cassidy Turley was acquired by a private equity investment consortium backed by TPG Capital, PAG Asia Capital and Ontario Teachers' Pension Plan.

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  2. Zippia score 4.6

    #2 Best start-up company to work for in Missouri
    Company description:

    Ad Knowledge based is to help people make their lives easier by gaining knowledge from the video.

  3. Zippia score 4.6

    #3 Best start-up company to work for in Missouri
    Company description:

    Viki is an international video website offering TV shows, movies, and other premium content translated into more than 150 languages by a community of avid fans.

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  4. Zippia score 4.4

    #4 Best start-up company to work for in Missouri
    Company description:

    KE2 Therm Solutions is a Washington, Missouri based company that specializes in the development of energy saving electronic controllers for refrigeration and air conditioning applications. They are merging energy saving electronics with customer service, product customization, and technical expertise. They are bridging the gap from mechanical to electronic HVACR systems, and helping their customers understand and utilize emerging electronic component technology -- saving energy, money and reducing their environmental impact.

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  5. Zippia score 4.4

    #5 Best start-up company to work for in Missouri
    Company description:

    Show Me Alternatives is a producer and healthcare provider of medical cannabis. Show Me Alternatives is a family-oriented and socially-conscious business that values respect for individualized patient-centered health and wellness. Its team commits to providing passionate and quality customer service through continuing education of our staff and community to create a positive experience. The company supports and empowers their patients by providing the highest quality of locally grown cannabis.

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  7. Zippia score 4.3

    Company description:

    PierianDx is catalyzing global adoption of genomic sequencing in healthcare by empowering physicians in the laboratory and clinic to more effectively diagnose and treat patients with cancer and other complex diseases. PierianDx's industry-leading genomic SaaS solutions, CAP and CLIA accredited laboratory, and shared knowledgebase are used by health systems, cancer centers and commercial laboratories worldwide driving the most integrated approach across the clinical care spectrum. From genomic sequencing and biomedical informatics in the laboratory to reporting and decision support at the patient's bedside, PierianDx has rapidly become the trusted source of ‘wisdom' in every advanced genomic report.

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  8. Zippia score 4.3

    Company description:

    BriteCore is an enterprise-level insurance processing suite. Built from the ground up using the latest in modern technology, BriteCore combines core, data, and digital solutions into a single platform. Deployed using the Amazon Web Services cloud, BriteCore is continually updated to guarantee maximum security, efficiency, and durability at scale. Insurance carriers, MGAs, and start-ups rely on BriteCore to increase speed to market, improve competitive position, and support growth.

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  9. Zippia score 4.2

    Company description:

    Forsyth Baldwin, LLC was incorporated in 2011 and is based in St. Louis, Missouri.

  10. Zippia score 4.2

  11. Zippia score 4.2

    Company description:

    Spear Power Systems designs and manufactures safe, reliable lithium ion battery storage systems for demanding applications including defense, marine propulsion, oil & gas, and mining.

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  12. Zippia score 4.2

    Company description:

    Katalyst Surgical, LLC provides titanium ophthalmic surgical instruments. It offers cannulas, forceps, hooks/manipulators, lasik products, needle holders, phaco choppers, scissors, speculum, and related products online. Katalyst Surgical, LLC was incorporated in 2010 and is based in Chesterfield, Missouri.

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  13. Zippia score 4.1

    Company description:

    MindMixer connects municipal decision makers and elected officials with their constituents in a cost-effective and engaging manner. Additionally, MindMixer provides an active and convenient way for citizens to be involved in guiding decisions and policy.

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  14. Zippia score 4.1

    Company mission statement:

    To provide excellent patient care and promote wellness throughout our communities.

  15. Zippia score 4.1

    Company description:

    Developing a new low carbon intensity winter crop for the Midwest. Allows 3 crops in 2 years, improving soil health and additional farm revenue!

  16. Zippia score 4.1

    Company description:

    We are a network of veterinary hospitals anchored by a deep commitment to the teams that serve our clients and patients.

  17. Zippia score 4.1

    Company description:

    DisruptOps is building a platform to bring unprecedented insight, control, and expertise into cloud environments. They enable organizations to realize the promise of the cloud by rethinking traditional security and operational approaches. With automated and continuous control of cloud infrastructure, teams can move faster into the cloud while strengthening security controls, streamlining operations, and controlling cloud spending.

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  18. Zippia score 4.1

    Company description:

    The company was started in 1998 as Deck Internet Solutions. As a services company our passion has been rooted in solving business problems related to eCommerce by leveraging technology. In 2015 we re-branded the company and launched our flagship eCommerce platform… Deck Commerce. Deck Commerce is the culmination of 15+ years of experience helping companies maximize their eCommerce potential. Engineered as a world-class transactional platform with powerful eCommerce functionality and integration capabilities, we are uniquely positioned to provide compelling value to customers, partners and employees alike.

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  19. Zippia score 4.0

    Company description:

    We enable agencies and their dealerships to look and feel like an administrator by being the best at private labeling and reinsurance participation.

  20. Zippia score 4.0

    Company description:

    Connecting you to the child in need. CarePortal is an online platform that brings the needs of hurting children and families in your community to your attention. Caseworkers uncover the needs. CarePortal makes local churches aware, giving them a real-t...

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  21. Zippia score 4.0

    Company description:

    PopBookings is a cloud-based software that automates the hiring process for event and promotional staffing companies.

  22. Zippia score 4.0

    Company description:

    Balto helps sales, service, and accounts receivable reps win as much revenue as possible from every phone call. Sales, service, and accounts receivable teams use Balto's artificial intelligence software to analyze phone calls in real time - live while the call is still happening - and instantly provides reps recommendations on how to communicate as effectively as possible before it's too late. Balto automatically guides reps to use the communication strategies managers wish they would implement on every call - the strategies that consistently produce revenue and prevent expensive compliance mistakes.

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  23. Zippia score 4.0

    Company description:

    Frontier Justice is the Premier Firearms, Fashion & Shooting Range Destination. We provide entertainment and education for the entire family.

  24. Zippia score 4.0

    Company description:

    Mycroft is a developer of an open source voice assistant platform designed to handle operating systems. The company's open source voice assistant platform is an artificial intelligence based software that offers natural language processing capability paired with an open-source and open-hardware approach, enabling users to handle their electronic items through voice.

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  25. Zippia score 4.0

    Company description:

    EndoStim is a St. Louis start-up that makes medical devices to treat gastrointestinal and urological neuro-muscular disorders. EndoStim is performing clinical trials to pursue FDA approval for a new treatment for sphincter-related disorders such as gastroesophageal reflux disease (GERD) and urinary urge incontinence. Drugs known as proton pump inhibitors (PPIs) are the standard of care for GERD treatment but they do not address the root-cause of GERD. In severe cases, patients may opt for surgical anti-reflux procedures that are costly and invasive. EndoStim has developed a procedure that offers a lower cost, interventional solution for treating severe or refractory GERD and reach the many patients currently unresponsive to or dissatisfied with their medical therapy. GERD affects hundreds of millions of patients worldwide, including 30 million in the United States.

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  26. Zippia score 3.9

    Company description:

    EquipmentShare creates proprietary technology and end-user applications that empowers contractors and optimizes for productivity across the commercial construction sector. Fleet managers, general contractors, service techs, heavy equipment mechanics, drivers, operators, safety managers are all experiencing new ways to work along with the benefits of a connected jobsite with EquipmentShare's tech-enabled product suite.

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  27. Zippia score 3.9

  28. Zippia score 3.9

    Company description:

    Clever Real Estate company that specializes in the fields of commercial real estate and online marketplace. It offers a software platform that guides its users through the process of interviewing real estate agents to find the right one for them. The company was founded in 2017 and headquartered in St Louis, Missouri.

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  29. Zippia score 3.9

    Company description:

    Epharmix is a digital healthcare company that creates clinically validated and condition-specific communication tools. It helps care teams automatically monitor underserved patients to improve care & reduce workload with interventions proven to impact engagement and outcomes. It was founded in 2015 and headquartered in St Louis, Missouri.

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  30. Zippia score 3.9

    Company description:

    DotCom Therapy specializes in providing speech therapy, occupational therapy, and mental health services via computer, tablet, or smartphone. They hand-match students, patients, and clients with our therapists who provide the highest quality therapy in a live, online, face-to-face setting. It offers speech, occupational and mental health therapy, educational audiology, case management, and literacy services. The company was founded in 2015 and is based in Madison, Wisconsin, United States.

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  31. Zippia score 3.9

    Company description:

    MowBotix is an autonomous platform that brings automation to mowing equipment. This automation allows commercial lawn care operators to increase their work capacity without expanding their current labor force.

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  32. Zippia score 3.9

    Company description:

    PayIt simplifies doing business with the state, local, and federal government through its patent-pending mobile transaction and payment platform. The company strives to provide an open Digital Government Platform that allows their partners and the industry to collaborate on providing the best solution to improve the delivery of government services to citizens. They deliver an innovative solution that enables residents to access essential government services from any device. PayIt was founded in 2013 and is headquartered in Kansas City, Missouri, United States.

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  33. Zippia score 3.8

    Company description:

    Staying Home Corporation is dedicated to providing innovative products and services that enables the aging in place to safely and economically stay in their home. Our commitment to integrity and quality is second to none!

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  34. Zippia score 3.8

    Company description:

    NewLeaf Symbiotics was formed in 2012 to develop and commercialize one of the most prevalent, beneficial bacteria found in nature: PPFMs (Pink Pigmented Facultative Methylotrophs). NewLeaf Symbiotics is the exclusive licensee of a number of patents on the use of this family of bacteria. NewLeaf Symbiotics has also filed its own related patents, and is actively developing new technologies related to PPFMs. The Company is engaged in laboratory, greenhouse, and field product trials and expects to commercialize and license products beginning in 2014.

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  35. Zippia score 3.8

    Company description:

    Lelex Prime is a developer of a artificial Intelligence tool designed to analyze scientific research, public information, and mathematically model the information. The company's tool infuses artificial intelligence, machine learning and natural language processing with social science research, enabling users to gain actionable insights to influence aspects such as consumer messaging, strategy and marketing campaigns.

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  36. Zippia score 3.8

    Company description:

    SUMMERSALT is disrupting the swimwear industry. An investor funded, direct to consumer swimwear brand, SUMMERSALT offers a $200 designer swimsuit for $95 and is the first to fully embrace the direct to consumer model as a category killer with both an affordable price point and try-at-home approach. The athleisure-inspired collection is made from all recycled materials, and painstakingly designed and fitted by their experienced team of designers and expert patternmakers. Founders, Lori Coulter and Reshma Chattaram Chamberlin, have a long history of successfully launching and growing both swimwear and direct to consumer brands. Meet SUMMERSALT, ‘Swimwear for life beyond the lounge chair'.

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  37. Zippia score 3.8

    Company description:

    Hedron, like Polyhedron. Building magical, visual software. It's VR, without the overhead! ❤️ https://t.co/YbB8ZKBNa9

  38. Zippia score 3.8

    Company description:

    We provide practical solutions nationwide to affordable housing-HRM Services.

  39. Zippia score 3.8

    Company description:

    LockerDome is an ad platform with a brain, designed specifically for performance-based advertising. The brain behind the platform is Neo, an in-house AI, which uses machine learning to process billions of data points and make intelligent decisions at lightning speed.

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  40. Zippia score 3.8

    Company description:

    Geniecast is transforming the way the world connects people, ideas and inspiration. We are curators, producers and distributors of the world's largest online marketplace of thought leaders, athletes, speakers, celebrities, facilitators and more - all available via two-way, live video broadcast.

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  41. Zippia score 3.8

    Company description:

    Vector Legal Method is a software-as-a-service litigation management platform, designed for lawyers by lawyers. Vector is the first collaborative platform that gives in-house attorneys centralized control of all their litigation cases. Through our proprietary technology, corporate legal departments gain: visibility into outside counsel activity, instant access to case information, increased control over the litigation process, and valuable time to refocus on strategic projects, all while significantly reducing billable costs.

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  42. Zippia score 3.8

    Company description:

    Clearent is a credit card processing company that provides payment processing services to financial institutions, ISOs and agents, developers, and merchants. It offers credit card, next-day funding, terminal, mobile phone, virtual terminal, and benefit services. The company helps its customers increase their merchant portfolios and profits. Founded in 2005, Clearent is based in Clayton, Michigan, United States.

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  43. Zippia score 3.7

    Company description:

    Sadar 3D, Inc. provides SADAR Vision, a transparent imaging technology for surveying, imaging, mapping, and visualization applications. It offers solutions, such as pre-dig surveys, subterranean machine vision, environmental surveys, utility surveys, and utility theft detection. Sadar 3D, Inc. was incorporated in 2011 and is based in St. Louis, Missouri.

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  44. Zippia score 3.7

    Company description:

    SteadyMD is a telehealth company that enables members and doctors to pair up, collaborate, and develop long-term personal relationships, completely online.The SteadyMD Matching Engine evaluates each new member and doctor across hundreds of medical, fitness, and lifestyle attributes to help spark a connection and pair them up successfully.The company offers services for primary care, functional medicine, pediatric care, and employers and is licensed and has members in all 50 U.S. states.SteadyMD doctors are partnered with a limited number of members and are conveniently available through text, phone, and video chat. The SteadyMD medical team retrieves and maintains health records, refers patients to local specialists, arranges tests and procedures, and generally influences all downstream care and health spending for that member.

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  45. Zippia score 3.7

  46. Zippia score 3.7

    Company description:

    In early 2014, Scripps purchased Newsy, a digital video news service that gave Scripps entry into the national news marketplace. The Columbia, Missouri-based startup serves a national digital audience with a curated approach to storytelling, and its video player can be found on many Scripps TV station websites. Newsy's engaging video news bites offer a broader view in a concise format. Through short video segments available on the web, mobile devices and OTT, Newsy advances the understanding of how a news story is covered by global media outlets - it offers context with convenience. Newsy received a 2014 and 2015 National Edward R. Murrow Award for Best Documentary. Newsy also has won Appy Awards, a Davey Award and a W3 Award. Its highly rated free apps are available from the Apple App Store, Google Play, the Windows Phone Marketplace and the Nokia Store.

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  47. Zippia score 3.7

    Company description:

    Keybot is a smart rental access Robot that automates access for rental properties. It has a smart lock and application, property managers can share keys digitally to verified third parties, rekey locks and manage access remotely. It was launched March 2016 and is headquartered in Saint Louis, Missouri.

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  48. Zippia score 3.7

    Company description:

    Invisibly is building a digital ecosystem for consumer attention & media consumption that generates improved scarcity and accountability.

  49. Zippia score 3.7

    Company description:

    The QuizRR training solutions are based on internationally recognized guidelines on sustainable development and corporate responsibility, enabling businesses to step up from mere compliance to become role models and drivers of change. Training with QuizRR is essentially about risk management and capacity building on human rights - enabling people to improve their lives. Beyond audit.

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  50. Zippia score 3.7

    Company description:

    The premium domain name whatayanuts.com is available for sale!

  51. Zippia score 3.7

    Company description:

    Idle Smart is an automated engine start stop solution that maintains fleet up-time as well as reducing overnight idle time.

  52. Zippia score 3.7

    Company description:

    Safe Smart Simple

  53. Zippia score 3.7

    Company description:

    StatRoute is a sports technology company providing subscription-based services for Fantasy Sports & Sports Betting Consumers. StatRoute exists to allow all consumers access to any stat, for any player or team in 5-seconds or less. This includes data points not seen anywhere else, on a platform that is customizable and personalized to your specific needs. StatRoute is in development to have solutions for NFL, NBA, and MLB by 2019.

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  54. Zippia score 3.7

    Company description:

    TruQC is cloud-based industrial painting job-site documentation for the iPad. Carefully developed to conform with industry standards and required reports, TruQC brings objectivity and efficiency back to the job-site. TruQC offers several job-site documentation report types for the iPad including Timesheet Report, Expense Report, Daily Inspection Report, Toolbox Talk Report, Weekly Environmental Report, Incident Report and Take 5 Report.

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  55. Zippia score 3.7

    Company description:

    IDC Projects changed names to Lumate. Advertisers want to know their Return On Investment when buying advertising. This is most easily done by a performance-based model such as paying per “unit”. Paying per click, call, action, lead, or purchase are all common forms of payment in mobile advertising. Publishers (developers or owners of mobile apps) want maximum revenue and to be compensated every time an ad is shown in their app property. If an ad is not relevant to a user, hence no action, they do not want to take on the losses associated with the payout that a different advertiser would have given them. They don't accept the risk and want to get paid regardless of performance. Mobile advertising is difficult to target because of an immature ad tech ecosystem that cannot use cookie-based technology. Even if data can be used, many advertisers are too small or lack the resources necessary for proper data analysis to effectively target an audience at scale. This inherently limits the overall market growth. Lumate assumes the business risk from mobile ad buyers and sellers by buying each mobile ad impression while only getting paid for performance. Advertisers can now participate in a far larger and growing market and pay on their required performance terms. Lumate always pays per impression so publishers also transfer any business risk to Lumate. Lumate, formerly IDC Projects, was founded in 2008. Lumate is based in downtown St Louis and is an Arch Grants, Capital Innovators, and Missouri Technology Corporations recipient.

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  56. Zippia score 3.7

    Company description:

    Branson Airport is a public use airport located eight nautical miles south-southeast of the central business district of Branson, a city in Taney County, Missouri, United States. It is privately owned by Branson Airport, LLC.

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  57. Zippia score 3.7

    Company mission statement:

    To help people improve their health by adjusting their lifestyle in accord with the basic principles of nature.

  58. Zippia score 3.7

    Company description:

    GIVVER, INC. provides a solution that enables users to tweet a donation to their organizations. The company was incorporated in 2012 and is based in St. Louis, Missouri.

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  59. Zippia score 3.6

  60. Zippia score 3.6

  61. Zippia score 3.6

  62. Zippia score 3.6

    Company description:

    It's not fantasy, it's sports!!

  63. Zippia score 3.6

    Company description:

    Evtron provides highly efficient affordable enterprise storage platforms with modular scalability.

  64. Zippia score 3.6

    Company description:

    Our mission is to produce healthy and delicious foods that you can be proud to feed to your family.

  65. Zippia score 3.6

    Company description:

    FinLocker is a financial services technology innovator, founded by a team of seasoned veterans and leading executives across the financial services and technology industries. FinLocker offers a solution capable of improving the loan process, from origination to servicing, and even beyond. It is a secure, transactional personal financial management tool that aggregates a consumer's financial data, and analyzes, recommends, streamlines mortgage and other financial transactions. Consumers benefit from personalized recommendations, financial, mortgage education, credit score, report, monitoring, cash flow analysis, budgeting, goal planning, data sharing, and more. It was founded in 2014 and is headquartered in St. Louis, Missouri.

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  66. Zippia score 3.5

    Company description:

    Cequel Data Centers, LLC owns and operates data centers. The company was founded in 2010 and is based in Saint Louis, Missouri.

  67. Zippia score 3.4

    Company description:

    Freely Pet is a producer of pet food supplies intended to provide quality pet food.The company's products are made with limited-ingredients and are nutrient rich, enabling pet owners to give proper nutrition to their pets.

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  68. Zippia score 3.4

    Company description:

    Real Estate for sale in Springfield/Branson and all of Southwest MO

  69. Zippia score 3.4

    Company description:

    Coolfire provides connected workstream collaboration software to enhance real-time event awareness, control, and response. By eliminating the barriers between operational teams and data, Coolfire empowers people to make better decisions faster. Connected teams see events as they happen, access highly organized workspaces with critical event data, and allow the assigned team to coordinate a response. By integrating cross-functional teams, assets, and event data into a common operational picture, organizations can orchestrate tasks, people and resources with greater visibility before, during and after the event. Built for the speed of the US Special Forces and for the scale of Enterprise Rent-A-Car.

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  70. Zippia score 3.4

    Company description:

    Mylo is the largest independent and unbiased insurance broker.

  71. Zippia score 3.3

    Company description:

    Bonfyre is an enterprise communications platform that is changing the way companies build culture and engage their employees. Our technology brings people together and helps organizations build camaraderie, align culture and drive real-time HR business intelligence.

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  72. Zippia score 3.3

    Company description:

    "The Tinderbox" is a literary fairy tale by Hans Christian Andersen about a soldier who acquires a magic tinderbox capable of summoning three powerful dogs to do his bidding.

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  73. Zippia score 3.0

    Company description:

    Geneoscopy is a non-invasive colorectal cancer diagnostic powered by advanced research in computational biology. The company is determined to replace every patient's least favorite screen: the colonoscopy. Currently there is no test with high enough specificity and sensitivity to allow patients an alternative to the unpleasant, invasive colonoscopy. Geneoscopy is changing that. It has developed a novel methodology to reliably and consistently extract human RNA transcripts from stool samples and detect changes in gene expression. This provides Geneoscopy a platform to harness the power of RNA to detect, prevent, and guide treatment for gastrointestinal disease. Geneoscopy is currently developing a diagnostic test for the prevention of colorectal cancer and is conducting research on other applications of its technology for tangential indications.

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Best start-up companies to work for headquartered in Missouri

RankCompanyZippia score
1Cassidy Turley4.7
2Adknowledge4.6
3Viki4.6
4KE2 Therm Solutions4.4
5Show Me Alternatives4.4
6PierianDx4.3
7BriteCore4.3
8Forsyth Baldwin LLC4.2
9DERMAdoctor4.2
10Spear Power Systems4.2
11Katalyst Surgical4.2
12MindMixer4.1
13Orizon4.1
14CoverCress4.1
15CareVet4.1
16DisruptOps4.1
17Deck Commerce4.1
18SideCars4.0
19CarePortal4.0
20PopBookings4.0
21Balto4.0
22Frontier Justice4.0
23Mycroft AI4.0
24EndoStim4.0
25EquipmentShare3.9
26MOZAIC GROUP LTD3.9
27Clever Real Estate3.9
28Epharmix3.9
29DotCom Therapy3.9
30MowBotix3.9
31PayIt3.9
32STAYING HOME3.8
33NewLeaf Symbiotics3.8
34Lelex Prime3.8
35Summersalt3.8
36Hedron Vision3.8
37HRM Services3.8
38LockerDome3.8
39Geniecast3.8
40Vector Legal Method3.8
41Clearent3.8
42SADAR 3D3.7
43SteadyMD3.7
44Callout3.7
45Newsy3.7
46Keybot3.7
47Invisibly3.7
48Quizrr3.7
49Whataya Nuts3.7
50Idle Smart3.7
51Island Radar3.7
52StatRoute3.7
53TruQC3.7
54Lumate3.7
55Branson Airport3.7
56BioMed Protect3.7
57Givver3.7
58Steadfast Capital3.6
59Adiby Inc3.6
60eHawk Inc3.6
61Fandom Cup3.6
62Evtron3.6
63Beyond Organic3.6
64FinLocker3.6
65Cequel 33.5
66Freely3.4
67Your New Home3.4
68Coolfire3.4
69Mylo, a Lockton3.4
70Bonfyre3.3
71The Tinderbox3.3
72Geneoscopy3.0

Start-up companies by city in Missouri