Senior Computational Biologist (Remote)
Remote computational linguist job
The Role
Join our team and help build the world's first biological reasoning model. Work with us to build generative foundational models that decode biological systems across scales - from molecules to organisms - enabling us to predict, understand, and program living systems in ways never before possible.
Output is currently in stealth, operated by a team of repeat founders and biotech veterans with multiple exits in AI x Bio, and backed by top-tier VCs including Y Combinator.
As a Senior Computational Biologist, you'll work alongside members of our research team and our founders to develop AI systems capable of complex biological reasoning across multiple scales.
You will develop machine learning methods to extend our predictive and generative platform
You will design and execute computational pipelines to validate and prioritized de novo generated molecules using state of the art tools
You will use your deep understanding of biology to design novel therapeutics for hard-to-target proteins with our generative models
You will analyze and integrate large-scale biological datasets
Your work will directly impact the development of our biologically-aware AI platform, transforming the landscape of medicine
Make a real tangible impact on millions of lives by pushing the boundaries of AI in biology.
Who We're Looking For
You have a PhD in a biological field and strong programming skills in Python
You have experience with computational biology tools such as structure prediction, molecular docking and virtual screening
You have experience working with Protein or Chemical Language Models
You like to work collaboratively in a fast-paced startup environment
You are passionate about using data science to unlock the secrets of biology
You exhibit a proactive approach to problem-solving, thinking beyond the specific task, taking ownership of challenges, and pride in solving them
You have a mature mindset in ambiguous situations, helping to frame questions and seek clarity while making decisions in the face of uncertainty
You have excellent communication skills and can clearly articulate complex technical concepts
You will be expected to travel periodically for in-person team meetings at our NYC HQ
Bonus Points
You have hands-on experience building AI/ML using PyTorch and Lightning
You have experience with cloud computing platforms like AWS
You have hands-on biology laboratory experience
You have contributed to peer-reviewed publications in computational biology
You have knowledge of machine learning techniques applied to biological data
Our Values
❤️ Heart: We foster a culture of ownership. We are assembling a team of individuals who are passionate and take pride in their contributions.
🏆 Excellence: We have an unwavering commitment to excellence and continuously challenge ourselves to reach the highest standards.
🚀 Practicality: We value practicality and results-oriented thinking. We are committed to making a tangible impact on the lives of patients and the broader community.
📣 Honesty: We place a high value on honesty and directness. We firmly believe in addressing issues as they arise, in an open and transparent manner.
🎮 Fun: We believe that life is too short to not have fun. Our goal is to create a workplace that is fun, engaging, rewarding and fulfilling.
What We Offer
We encourage new and different ideas, creativity and contrarian thinking
Healthy feedback focused environment to help you strive - leadership will have high expectations, regularly share constructive feedback, support you and help you grow, and welcome receiving feedback and ideas from you
You own your day-to-day management. What we care about is that we all hit our milestones
Competitive salary and equity in a growing, well-funded startup
Excellent medical, dental, and vision coverage
Auto-ApplyComputational Biologist
Remote computational linguist job
The Brenden-Colson Center for Pancreatic Care (BCCPC) seeks a computational biologist who will work in an interdisciplinary environment, leveraging their skills in bioinformatics, data analysis, and machine learning to understand the complexities of pancreatic cancer development, progression, and treatment response. They will develop, adapt and implement bioinformatics pipelines, analytical and theoretical methods, and collaborate with experimental biologists to analyze data relevant to pancreatic disease, especially advanced treatment and early detection of pancreatic cancer.
The BCCPC is comprised of a collaborative group of senior scientists in the OHSU School of Medicine. This position will work closely with BCCPC Program Leaders and staff on computational aspects of all pancreas research efforts within the Center. They will draw upon skills in algorithm deployment, modeling, and statistics to make inferences from complex datasets, and implement scalable high-performance workflows in pancreatic cancer research. They will provide assistance with software best practices and collaborate to build, publish, and reuse open source code. They will perform data analysis and interpretation, and provide documentation and user support for pancreas researchers and research publications. They will assist with mentorship of trainees and staff in this area of the science, maintain a strong understanding of current scientific literature, and communicate findings clearly to a variety of audiences.
The ability to meet deadlines, research goals, and milestones are essential. This position will be working on a variety of BCCPC pancreas research projects, including corporate partnerships and NIH-funded collaborative grants, through all phases from initiation to closing, collaborating with wet lab scientists, clinicians, computer scientists and software engineers. The work includes applied algorithmic work, data science & data visualization, statistical learning & classical ML, but also cloud computing & high-performance computing on computer clusters, all as related to pancreatic disease research. This person will be actively engaged and accountable for the development of technical deliverables.
We are looking for an enthusiastic individual who is willing to take initiative and implement systems to identify tasks and track progress. Experience with computational biology, signaling networks, and sequencing data and image analysis is desirable. An exceptional command of computational biology is required, and excellent verbal and written communication skills are essential. Salary will be commensurate with experience.
Function/Duties of Position
* Data Organization and Management: Requirements gathering; Clean and manage metadata; Access, store, and document raw data; Coordinate with pancreas research project team members; Meet publication requirements, including data and code repositing
* Platform development: Develop and apply data-analytical and theoretical methods, mathematical modeling and computational simulation techniques to apply to pancreatic cancer; Assist in implementing scalable high-performance workflows and creating documentation and providing user support
* Data Analysis: Sample/sequencing quality control assessment; Implement existing analytic packages and workflows; Adapt existing resources as needed to meet pancreatic cancer project needs
* Technical Writing/Communication: Present at regular team meetings; Clear code documentation; Support manuscript preparation; Support grant writing efforts
* Training and Mentorship: Work with pancreas research staff and trainees to further their understanding of computational biology needs and techniques
Required Qualifications
* Master's Degree in Computational Biology or related field ORBachelor's Degree in Computational Biology or related field AND3 years of relevant experience
* Experience with processing and analyzing next generation genome (DNA) and transcriptome (RNA) sequencing data; experience with single-cell sequencing data
* Trained in computational biology field and practice
* Experience in implementing statistical methods as appropriate for dataset treatment (e.g. quality inspection, normalization, differential feature detection, etc.)
* Experience in using pipelines to support analytics as described to additionally facilitate improved data management, and to generate complete workflows that are reproducible and scalable
* Competency in an appropriate programming language (R and/or Python)
* An understanding of a variety of sophisticated statistical methods for data treatment
* Ability to work independently and as part of a team while being collaborative in resolving problems and guiding project direction
* Ability to use tact and diplomacy to maintain effective working relationships
* Strong understanding of life science technology and jargon
* Excellent organizational skills, attention to detail, judgment, and discretion
* Must have excellent communication (both written and verbal), analytical and organizational skills
* Ability to prioritize multiple tasks at one time
Preferred Qualifications
* Cancer research experience; experience with signaling network analysis; experience with image processing and analysis pipelines
Additional Details
Work is generally 40 hours per week during normal working hours, however, some evening and weekend work may be necessary. May include occasional travel to scientific meetings for educational purposes and/or for data presentations. This position is eligible for hybrid/remote work only after an initial 4-month period. Details regarding schedule, required technology, environment and other OHSU conditions are to be detailed in the remote work documentation filled out by the employee and supervisor and approved by the supervisor.
Ability to use hands to work with a computer with long periods of sitting and/or standing. This function can be very repetitive. Ability to ride the aerial tram and walk long distances across campus.
All are welcome
Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at ************ or *************.
Auto-ApplyComputational Biologist
Remote computational linguist job
The Brenden-Colson Center for Pancreatic Care (BCCPC) seeks a computational biologist who will work in an interdisciplinary environment, leveraging their skills in bioinformatics, data analysis, and machine learning to understand the complexities of pancreatic cancer development, progression, and treatment response. They will develop, adapt and implement bioinformatics pipelines, analytical and theoretical methods, and collaborate with experimental biologists to analyze data relevant to pancreatic disease, especially advanced treatment and early detection of pancreatic cancer.
The BCCPC is comprised of a collaborative group of senior scientists in the OHSU School of Medicine. This position will work closely with BCCPC Program Leaders and staff on computational aspects of all pancreas research efforts within the Center. They will draw upon skills in algorithm deployment, modeling, and statistics to make inferences from complex datasets, and implement scalable high-performance workflows in pancreatic cancer research. They will provide assistance with software best practices and collaborate to build, publish, and reuse open source code. They will perform data analysis and interpretation, and provide documentation and user support for pancreas researchers and research publications. They will assist with mentorship of trainees and staff in this area of the science, maintain a strong understanding of current scientific literature, and communicate findings clearly to a variety of audiences.
The ability to meet deadlines, research goals, and milestones are essential. This position will be working on a variety of BCCPC pancreas research projects, including corporate partnerships and NIH-funded collaborative grants, through all phases from initiation to closing, collaborating with wet lab scientists, clinicians, computer scientists and software engineers. The work includes applied algorithmic work, data science & data visualization, statistical learning & classical ML, but also cloud computing & high-performance computing on computer clusters, all as related to pancreatic disease research. This person will be actively engaged and accountable for the development of technical deliverables.
We are looking for an enthusiastic individual who is willing to take initiative and implement systems to identify tasks and track progress. Experience with computational biology, signaling networks, and sequencing data and image analysis is desirable. An exceptional command of computational biology is required, and excellent verbal and written communication skills are essential. Salary will be commensurate with experience.
Function/Duties of Position
Data Organization and Management: Requirements gathering; Clean and manage metadata; Access, store, and document raw data; Coordinate with pancreas research project team members; Meet publication requirements, including data and code repositing
Platform development: Develop and apply data-analytical and theoretical methods, mathematical modeling and computational simulation techniques to apply to pancreatic cancer; Assist in implementing scalable high-performance workflows and creating documentation and providing user support
Data Analysis: Sample/sequencing quality control assessment; Implement existing analytic packages and workflows; Adapt existing resources as needed to meet pancreatic cancer project needs
Technical Writing/Communication: Present at regular team meetings; Clear code documentation; Support manuscript preparation; Support grant writing efforts
Training and Mentorship: Work with pancreas research staff and trainees to further their understanding of computational biology needs and techniques
Required Qualifications
Master's Degree in Computational Biology or related field OR
Bachelor's Degree in Computational Biology or related field AND
3 years of relevant experience
Experience with processing and analyzing next generation genome (DNA) and transcriptome (RNA) sequencing data; experience with single-cell sequencing data
Trained in computational biology field and practice
Experience in implementing statistical methods as appropriate for dataset treatment (e.g. quality inspection, normalization, differential feature detection, etc.)
Experience in using pipelines to support analytics as described to additionally facilitate improved data management, and to generate complete workflows that are reproducible and scalable
Competency in an appropriate programming language (R and/or Python)
An understanding of a variety of sophisticated statistical methods for data treatment
Ability to work independently and as part of a team while being collaborative in resolving problems and guiding project direction
Ability to use tact and diplomacy to maintain effective working relationships
Strong understanding of life science technology and jargon
Excellent organizational skills, attention to detail, judgment, and discretion
Must have excellent communication (both written and verbal), analytical and organizational skills
Ability to prioritize multiple tasks at one time
Preferred Qualifications
Cancer research experience; experience with signaling network analysis; experience with image processing and analysis pipelines
Additional Details
Work is generally 40 hours per week during normal working hours, however, some evening and weekend work may be necessary. May include occasional travel to scientific meetings for educational purposes and/or for data presentations. This position is eligible for hybrid/remote work only after an initial 4-month period. Details regarding schedule, required technology, environment and other OHSU conditions are to be detailed in the remote work documentation filled out by the employee and supervisor and approved by the supervisor.
Ability to use hands to work with a computer with long periods of sitting and/or standing. This function can be very repetitive. Ability to ride the aerial tram and walk long distances across campus.
All are welcome Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at ************ or *************.
Auto-ApplyComputational Biologist
Remote computational linguist job
The Brenden-Colson Center for Pancreatic Care (BCCPC) seeks a computational biologist who will work in an interdisciplinary environment, leveraging their skills in bioinformatics, data analysis, and machine learning to understand the complexities of pancreatic cancer development, progression, and treatment response. They will develop, adapt and implement bioinformatics pipelines, analytical and theoretical methods, and collaborate with experimental biologists to analyze data relevant to pancreatic disease, especially advanced treatment and early detection of pancreatic cancer.
The BCCPC is comprised of a collaborative group of senior scientists in the OHSU School of Medicine. This position will work closely with BCCPC Program Leaders and staff on computational aspects of all pancreas research efforts within the Center. They will draw upon skills in algorithm deployment, modeling, and statistics to make inferences from complex datasets, and implement scalable high-performance workflows in pancreatic cancer research. They will provide assistance with software best practices and collaborate to build, publish, and reuse open source code. They will perform data analysis and interpretation, and provide documentation and user support for pancreas researchers and research publications. They will assist with mentorship of trainees and staff in this area of the science, maintain a strong understanding of current scientific literature, and communicate findings clearly to a variety of audiences.
The ability to meet deadlines, research goals, and milestones are essential. This position will be working on a variety of BCCPC pancreas research projects, including corporate partnerships and NIH-funded collaborative grants, through all phases from initiation to closing, collaborating with wet lab scientists, clinicians, computer scientists and software engineers. The work includes applied algorithmic work, data science & data visualization, statistical learning & classical ML, but also cloud computing & high-performance computing on computer clusters, all as related to pancreatic disease research. This person will be actively engaged and accountable for the development of technical deliverables.
We are looking for an enthusiastic individual who is willing to take initiative and implement systems to identify tasks and track progress. Experience with computational biology, signaling networks, and sequencing data and image analysis is desirable. An exceptional command of computational biology is required, and excellent verbal and written communication skills are essential. Salary will be commensurate with experience.
Function/Duties of Position
Data Organization and Management: Requirements gathering; Clean and manage metadata; Access, store, and document raw data; Coordinate with pancreas research project team members; Meet publication requirements, including data and code repositing
Platform development: Develop and apply data-analytical and theoretical methods, mathematical modeling and computational simulation techniques to apply to pancreatic cancer; Assist in implementing scalable high-performance workflows and creating documentation and providing user support
Data Analysis: Sample/sequencing quality control assessment; Implement existing analytic packages and workflows; Adapt existing resources as needed to meet pancreatic cancer project needs
Technical Writing/Communication: Present at regular team meetings; Clear code documentation; Support manuscript preparation; Support grant writing efforts
Training and Mentorship: Work with pancreas research staff and trainees to further their understanding of computational biology needs and techniques
Required Qualifications
Master's Degree in Computational Biology or related field OR
Bachelor's Degree in Computational Biology or related field AND
3 years of relevant experience
Experience with processing and analyzing next generation genome (DNA) and transcriptome (RNA) sequencing data; experience with single-cell sequencing data
Trained in computational biology field and practice
Experience in implementing statistical methods as appropriate for dataset treatment (e.g. quality inspection, normalization, differential feature detection, etc.)
Experience in using pipelines to support analytics as described to additionally facilitate improved data management, and to generate complete workflows that are reproducible and scalable
Competency in an appropriate programming language (R and/or Python)
An understanding of a variety of sophisticated statistical methods for data treatment
Ability to work independently and as part of a team while being collaborative in resolving problems and guiding project direction
Ability to use tact and diplomacy to maintain effective working relationships
Strong understanding of life science technology and jargon
Excellent organizational skills, attention to detail, judgment, and discretion
Must have excellent communication (both written and verbal), analytical and organizational skills
Ability to prioritize multiple tasks at one time
Preferred Qualifications
Cancer research experience; experience with signaling network analysis; experience with image processing and analysis pipelines
Additional Details
Work is generally 40 hours per week during normal working hours, however, some evening and weekend work may be necessary. May include occasional travel to scientific meetings for educational purposes and/or for data presentations. This position is eligible for hybrid/remote work only after an initial 4-month period. Details regarding schedule, required technology, environment and other OHSU conditions are to be detailed in the remote work documentation filled out by the employee and supervisor and approved by the supervisor.
Ability to use hands to work with a computer with long periods of sitting and/or standing. This function can be very repetitive. Ability to ride the aerial tram and walk long distances across campus.
All are welcome Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at ************ or *************.
Auto-Apply