Scientist jobs at Dana-Farber Cancer Institute

The Belfer Center for Applied Cancer Science is an integrative research center within Dana-Farber Cancer Institute. Our mission is to enhance and accelerate oncology drug discovery & development through bridging of academia, industry, and clinical research. We apply industrial capabilities to cutting edge academic/clinical science. We partner with industry in drug discovery/development & work with industrial partners to delineate the clinical path of novel therapies for cancer patients. This integrated, goal-oriented organization represents a new academic construct that provides an unprecedented opportunity to change the way anti-cancer therapeutics are discovered and developed. For more information please visit: ************************************* Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. Responsibilities * Lead multi-laboratory collaborations to characterize novel targets and therapeutic approaches for cancer * Design experiments and execute on protocols; propose modification to protocols as needed * Maintain accurate records, write reports, and prepare presentations * Contribute to project team as well as overall laboratory organization and safety * Operation and maintenance of mass spectrometer instrumentation * Manage project Team Qualifications * Ph.D. in mass spectrometry or related field with 4-5 years experience * Experience working in proteomics and biochemistry * Experience performing quantitative mass spectrometry assays * Familiarity with Thermo instrumentation (Eclipse, Fusion, Q Exactive Plus, EASY-nLC, Astral-Orbitrap) * Familiarity with mass spectrometry methods (DIA, DDA, TMT-MS3, MRM, PRM, Intact Mass, etc.) * Independent, self-motivated, and innovative * Excellent written and oral communication skills * Outstanding interpersonal and team skills * Ability to excel in a goal-oriented and fast-moving team environment * Basic immunology a plus Pay Transparency Statement The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications. For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA) $74,600 - $82,900 At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply. Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law. EEOC Poster

Site: The Brigham and Women's Hospital, Inc. Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. Job Summary Summary In consultation with their Principal Investigator (PI), undertake and execute a program of scientific study culminating in publication. Drives research projects scientifically and determines the course of research as evidenced by leadership, obtaining funding, writing, or other recognition. May not necessarily receive independent resources; however, their contribution is essential to the conceptual/scientific success of the project. They assist their PI in the training and supervision of other laboratory personnel and in a wide variety of administrative tasks, as necessary. Does this position require Patient Care? No Essential Functions * Makes proficient intellectual contributions to scientific strategies of the group/lab and plays a leadership role by acting as subject matter authority in the field. * Contributes to the design and execution of experiments and/or research projects. * Exercises judgment in selecting methods and technologies to obtain results. * May collaborate with external researchers and/or receive external project funding support. * Presents results and prepares publications. * May assist PI in the training and supervision of other staff. Qualifications This position in the BWH Center for Cellular Profiling offers the opportunity to join a group studying single-cell and Spatial organization in disease pathology. Our Center performs a combination of high-dimensional analyses, including single-cell RNA sequencing, spatial transcriptomics, and high-dimensional flow cytometry. Under general supervision by Drs. Brenner and Wei, and in accordance with established hospital policies and procedures, the self-motivated individual will perform activities related to the single-cell genomics and or flow cytometry cell sorting, including NGS library generation, 10X Genomics workflow (Chromium, Visium, and Xenium), and or familiarize with BD or Sony cell sorters and analyzers. Responsibilities includes the implementation and execution of single-cell and novel spatial transcriptomic techniques. In addition, the candidate will supervise trainees and technicians to perform NGS and 10X Genomics pipelines. The candidate will also conduct consultation with investigators and core users, perform troubleshooting, and work with administrative directors to support budget development and planning. 1. Designs and performs high-level, complex experiments independently. 2. Perform Single-cell Transcriptomics Experiments. a. Cell capture, NGS library generation, b. Plan library sequencing strategies. c. Review sequencing data d. troubleshoot techniques 3. Perform High-Parameters Flow Cytometry Experiments a. Perform cell sorting b. Maintenance of the cell sorters and analyzers c. Identify and resolve technical issues with flow cytometry instruments, maintaining equipment, and ensuring quality control. 4.Supervise research assistant trainees. 5.Provide consultation with new investigators and researchers 6.Maintain supplies inventory in accordance with laboratory and department procedures. 7.Assist in the orientation and training of new students, technicians, and fellows 8.Maintain established department policies, procedures and objectives, including the areas of quality assurance, safety, environmental and infection control. 9. Perform other duties as directed. Education Doctorate Related Field of Study required Can this role accept experience in lieu of a degree? No Licenses and Credentials Experience Previous Research experience (inclusive of graduate and postdoctoral experience) 5-7 years required Knowledge, Skills and Abilities * Excellent research skills. * Demonstrated evidence of specific scientific competence in field. * Demonstrated broad knowledge of field. * Evidence of potential for scientific creativity and original though. * Able to exercise independent judgment and leadership. * Ability to contribute to publications. Additional Job Details (if applicable) Remote Type Onsite Work Location 60 Fenwood Road Scheduled Weekly Hours 40 Employee Type Regular Work Shift Day (United States of America) EEO Statement: The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at **************. Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership "looks like" by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.

Site: The Brigham and Women's Hospital, Inc. Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. Job Summary A research laboratory within the Brigham and Women's Hospital Division of Cardiovascular Medicine is seeking a highly motivated Research Scientist to join a growing, interdisciplinary team. The lab uses both in vitro (human ESC/iPSC) and in vivo (zebrafish) systems to model cardiovascular disorders and integrates transcriptional, (epi)genetic, metabolic, and phenotypic profiling at whole-organism, tissue, and single-cell levels. Our goal is to define the earliest molecular events driving disease onset, characterize their dynamic changes over time, and identify novel biomarkers and therapeutic targets. The Research Scientist will lead and directly perform automated, high-throughput microscopy screens to identify small-molecule compounds with improved efficacy over current clinical therapies. The role will involve hands-on execution of complex imaging workflows and the application of machine-learning approaches to large-scale imaging and phenotyping datasets. In addition, the Research Scientist will serve as the primary scientific point person for multiple industry collaborations, coordinating experimental design, execution, data generation, and communication between external partners and the lab. The Research Scientist will independently drive scientific projects, determine research direction in collaboration with the PI, and serve as an internal expert in automated imaging and computational analysis. The successful candidate will generate high-quality data, contribute substantially to scientific publications, mentor junior staff, engage with collaborators, and may participate in the development of external funding applications. Qualifications GENERAL SUMMARY/ OVERVIEW STATEMENT: A research laboratory within the Brigham and Women's Hospital Division of Cardiovascular Medicine is seeking a highly motivated Research Scientist to join a growing, interdisciplinary team. The lab uses both in vitro (human ESC/iPSC) and in vivo (zebrafish) systems to model cardiovascular disorders and integrates transcriptional, (epi)genetic, metabolic, and phenotypic profiling at whole-organism, tissue, and single-cell levels. Our goal is to define the earliest molecular events driving disease onset, characterize their dynamic changes over time, and identify novel biomarkers and therapeutic targets. The Research Scientist will lead and directly perform automated, high-throughput microscopy screens to identify small-molecule compounds with improved efficacy over current clinical therapies. The role will involve hands-on execution of complex imaging workflows and the application of machine-learning approaches to large-scale imaging and phenotyping datasets. In addition, the Research Scientist will serve as the primary scientific point person for multiple industry collaborations, coordinating experimental design, execution, data generation, and communication between external partners and the lab. The Research Scientist will independently drive scientific projects, determine research direction in collaboration with the PI, and serve as an internal expert in automated imaging and computational analysis. The successful candidate will generate high-quality data, contribute substantially to scientific publications, mentor junior staff, engage with collaborators, and may participate in the development of external funding applications. PRINCIPAL DUTIES AND RESPONSIBILITIES: * Provide overall scientific leadership and project management for assigned research initiatives, including direct execution of experimental work. * Design, optimize, and perform high-throughput automated imaging and screening assays, including day-to-day hands-on operation of imaging platforms and related instruments. * Conduct complex and innovative experiments using in vitro (human ESC/iPSC) and in vivo (zebrafish) models; troubleshoot technical challenges and refine protocols as needed. * Serve as a subject-matter expert while actively generating data, maintaining experimental quality, and ensuring reproducibility. * Exercise professional judgment in selecting experimental strategies, technologies, and analytical methods to obtain high-quality results. * Make project-level decisions to address and resolve critical scientific or technical challenges. * Regularly present results to the PI and contribute to preparation of manuscripts, reports, and presentations. * Collaborate with external partners as the scientific point person for industry-funded projects, ensuring high-quality and timely experimental deliverables. * Maintain an active publication record as senior author or substantial contributor, demonstrating scientific independence. * Participate in relevant scientific societies, committees, and professional activities. * Train and mentor junior research staff in laboratory techniques, data analysis approaches, and best practices in research execution. * Contribute to long-term strategic planning for the laboratory's research direction, technologies, and collaborative projects. QUALIFICATIONS: * PhD in molecular biology, molecular genetics, or a closely related field strongly preferred; an MS with substantial additional experience may be considered. * Prior experience with zebrafish research is required. * Minimum of 5 years of relevant research experience, including demonstrated independence. SKILLS/ ABILITIES/ COMPETENCIES REQUIRED: * Strong expertise and technical proficiency in molecular biology, cell biology, and genetics. * Demonstrated experience using model organisms (preferably zebrafish) for high-throughput drug or modifier screens. * Proven ability to design, execute, and troubleshoot complex research projects. * Ability to define project objectives, develop experimental approaches, and interpret results. * Strong scientific writing skills with a record of impactful contributions to peer-reviewed publications. * Excellent organizational, communication, and leadership skills. * Ability to work both independently and collaboratively within a multidisciplinary research team. WORKING CONDITIONS: Wet-lab/office setting. SUPERVISORY RESPONSIBILITY: May be responsible for managing junior staff or research assistants. Additional Job Details (if applicable) Remote Type Onsite Work Location 221 Longwood Avenue Scheduled Weekly Hours 40 Employee Type Regular Work Shift Day (United States of America) EEO Statement: The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at **************. Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership "looks like" by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.

Site: The General Hospital Corporation Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. Job Summary Please email all materials to the Fellowship Director, Roger Dias, MD, PhD, MBA at ********************* by July 31st, 2025. The Neil and Elise Wallace STRATUS Center for Medical Simulation is committed to advancing medical education, patient safety, and healthcare outcomes through cutting-edge applications of medical simulation technologies supported by innovative curricula, contemporary educational methodologies, continuous improvement, and rigorous, multidisciplinary research. At STRATUS, the Medical AI & Cognitive (MAICE) Lab, led by Dr. Roger Dias, MD, PhD, MBA, brings together a multidisciplinary team of clinicians, engineers, psychologists, computer scientists, and educators, including collaborations with several scientists and institutions, nationally and internationally. The core mission of our research lab involves the use of cutting-edge technologies to objectively measure and improve clinicians' performance, with the ultimate goal of enhancing patient safety and improving clinical outcomes. Our projects have been funded by NASA, NIH, DoD, and NSF, leveraging machine learning and artificial intelligence to support high-performance clinical care in a variety of settings, including emergency medicine, critical care, surgery, space, and military medicine. The Postdoctoral Fellowship in Medical AI is intended for graduates of doctoral programs in Science, Technology, Engineering, and Mathematics (STEM) with a solid foundation in applying advanced ML/AI techniques to tackle complex problems in healthcare. The program is ideal for early-career scientists seeking additional experience in the healthcare field, as well as opportunities to apply AI/ML technologies and software engineering to improve patient care and safety. The research fellow will be mentored by a multidisciplinary team of experts, allowing her/him to gain extensive knowledge and experience in diverse research areas including medicine, human factors, cognitive science, behavioral sciences, and aerospace and military research. The successful candidate will conduct research and development within the emerging field of medical AI, applying advanced programming and software engineering skills. The research fellow will design and develop software architectures and train and evaluate ML/AI models to create AI-based solutions and integrate them with large multi-source clinical databases, including time-series physiological data, demographics, behavioral and psychological assessments, video, audio, electronic health records (EHR), and clinical performance outcomes. The fellow will also develop AI-based medical simulation applications and real-time clinical decision support systems. Qualifications Required: All applicants must have a Ph.D. in a STEM discipline, with extensive knowledge, skills, and demonstrated experience in software development, AI/ML modeling and evaluations. These are the required qualifications: Proficiency in Python and/or C++ Familiar with signal processing and time series analysis Familiar with cloud computing services and API Demonstrated experience with AI/ML training and model evaluations, including neural networks and/or large language models Demonstrated experience with TensorFlow and/or PyTorch and/or Scikit-learn Demonstrated prior experience in applying AI/ML in the medical field Demonstrates research experience as lead author in peer-reviewed scientific publications Preferred: Previous experience with computer vision (e.g., convolutional neural networks) and/or visual language models Salary and Benefits The selected candidate will be appointed for two years, with the opportunity to renew the appointment for a third and/or fourth year pending performance review and funding. Salary will be commensurate with experience, based on BWH guidelines for postdoctoral trainees. Benefits include comprehensive health insurance, optional dental, vision, and retirement plans, and reimbursement for conference travel related to fellowship projects. BWH is a Harvard-affiliated Teaching Hospital, and the research fellow with be eligible for an appointment at Harvard Medical School. The following items are considered in the application process: 1. Current CV 2. Recent work sample (e.g., peer-reviewed manuscript, pre-print, GitHub code, software demo) 3. At least three peer-reviewed publications in which the candidate was a significant contributor 3. Candidates selected for an interview will be asked to submit two letters of recommendation. Application materials & queries should be emailed to: Roger Dias, MD, PhD, MBA at ********************* Director of Research & Innovation Associate Professor of Emergency Medicine, Harvard Medical School Additional Job Details (if applicable) Remote Type Hybrid Work Location 10 Vining Street EEO Statement: The General Hospital Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at **************. Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.

Site: The Brigham and Women's Hospital, Inc. Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. Job Summary Summary Independently carries out a broad range of technically advanced research activities and procedures related to cancer drug policy; conceives of and designs experiments, evaluates conclusions, and has complete latitude to modify or devise methods and techniques as necessary to achieve desired results related to cancer drug policy; may supervise technical and administrative elements of research unit related to cancer drug policy. Essential Functions * Function as a skilled scientific specialist for the research unit or for a specific research project related to cancer drug policy. * Conducts broad range of experiments or computational analyses involving advanced technology/strategies related to cancer drug policy; conceives of the objective of research studies and designs experimental protocols/computational analyses to achieve the objectives related to cancer drug policy; generates, analyzes and evaluates experimental data; interprets the results of experiments/computational analyses related to cancer drug policy. * Writes and edits material for publication related to cancer drug policy; may present papers or appear as principal or secondary author in publications related to cancer drug policy. * Provides direct supervision to technical and support personnel as assigned related to cancer drug policy. * Provides instruction in laboratory or computational techniques and methodology to students and postdoctoral fellows related to cancer drug policy. * Performs other duties as assigned related to cancer drug policy * Complies with all policies and standards * Does this position require Patient Care (indirect/direct)? No Qualifications Education Doctorate Related Field of Study required Can this role accept experience in lieu of a degree? No Licenses and Credentials Experience Experience in an academic or laboratory research setting 5-7 years required Knowledge, Skills and Abilities * Proficiency in supply chain and vendor management. * Ability to identify problems and troubleshoot solutions. * Well-versed in laboratory standards and practices. * Good organizational skills, detail-oriented. * Sound degree of computer literacy. * Ability to methodically record data. * Good interpersonal and communication skills. * Broad knowledge of scientific principles, biological structures, and laboratory techniques. Additional Job Details (if applicable) Physical Requirements * Standing Frequently (34-66%) * Walking Frequently (34-66%) * Sitting Occasionally (3-33%) * Lifting Frequently (34-66%) 35lbs+ (w/assisted device) * Carrying Frequently (34-66%) 20lbs - 35lbs * Pushing Occasionally (3-33%) * Pulling Occasionally (3-33%) * Climbing Rarely (Less than 2%) * Balancing Frequently (34-66%) * Stooping Occasionally (3-33%) * Kneeling Occasionally (3-33%) * Crouching Occasionally (3-33%) * Crawling Rarely (Less than 2%) * Reaching Frequently (34-66%) * Gross Manipulation (Handling) Frequently (34-66%) * Fine Manipulation (Fingering) Frequently (34-66%) * Feeling Constantly (67-100%) * Foot Use Rarely (Less than 2%) * Vision - Far Constantly (67-100%) * Vision - Near Constantly (67-100%) * Talking Constantly (67-100%) * Hearing Constantly (67-100%) Remote Type Hybrid Work Location 1620 Tremont Street Scheduled Weekly Hours 40 Employee Type Regular Work Shift Day (United States of America) EEO Statement: The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at **************. Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership "looks like" by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.

Site: The Brigham and Women's Hospital, Inc. Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. We're offering a generous sign-on bonus of $10,000 to eligible candidates who join our team. Recognizing and valuing exceptional talent, we're excited to discuss the details of this bonus during the interview process. Job Summary Summary As required by CLIA, testing personnel are responsible for specimen processing, test performance, and reporting test results. Each individual performs only those tests authorized by the laboratory director and requiring a level of skill appropriate to their education, training, experience, and technical abilities. The role requires working independently in an efficient and organized manner to ensure accurate results and documentation. This position requires professional-level knowledge to accurately read and interpret test results used by providers in diagnosing and treating diseases. The Medical Laboratory Scientist, Senior I, in their role as Technical Supervisor, Technical Consultant, or General Supervisor as defined by CLIA, may be delegated responsibility for technical oversight of the laboratory, including day-to-day supervision of operations and personnel performing testing and reporting results. Under the general supervision of the Technical Director and Clinical Supervisors, the Senior Technologist I also oversees assigned workstations, including Quality Control (QC) review, staff training, competency assessments, and inventory management. Does this position require patient care? No Essential Functions After successful completion of orientation, training, and competency assessment on all applicable instruments and methods, the Senior Technologist I must: Follow the laboratory's procedures for specimen handling and processing, test analyses, reporting, and recordkeeping. Maintain records demonstrating that proficiency testing samples are analyzed in the same manner as patient samples. Adhere to quality control policies and document all QC activities, calibrations, and maintenance. Follow established corrective action procedures when test systems fall outside acceptable performance standards. Identify issues that may adversely affect test performance or result reporting, and either correct them or immediately notify the appropriate supervisor or director. Document all corrective actions taken when test systems deviate from established performance specifications, in accordance with 42 CFR 493.1425 and 493.1495. Qualifications Education Bachelor's Degree Clinical Laboratory Sciences required or Bachelor's Degree Medical Technology required or Bachelor's Degree Laboratory Sciences required and Can this role accept experience in lieu of a degree? No Licenses and Credentials Medical Technologist (ASCP) [MLT, MT, MLA, Histologists] - American Society for Clinical Pathology Board of Certification (ASCP-BOC) required Experience lab experience 4 years required Knowledge, Skills and Abilities * The knowledge, both practical and theoretical, of tests and procedures necessary to review findings and advise and direct subordinates in action. * Demonstrates advanced level of analytical skills and judgement. * Must have understanding of computer technology and its application to analytical procedures and quality control. * Must have a comprehensive understanding of laboratory equipment and its operation, maintenance, and repair, and analytic techniques. * Must have the ability to work independently, evaluate situations and act appropriately. * Ability to multitask in a fast-paced environment. * Must have the ability to pay careful attention to detail and to adhere to written protocols, including communication with supervisors when issues are identified. * Must be able to perform as a team member. * Excellent interpersonal skills. * Ability to interact professionally and effectively with numerous staff including physicians, hospital personnel, employees, and patients. * Advanced knowledge of federal, state and accreditation requirements. Additional Job Details (if applicable) Physical RequirementsStanding Frequently (34-66%) Walking Frequently (34-66%) Sitting Occasionally (3-33%) Lifting Frequently (34-66%) 35lbs+ (w/assisted device) Carrying Frequently (34-66%) 20lbs - 35lbs Pushing Occasionally (3-33%) Pulling Occasionally (3-33%) Climbing Rarely (Less than 2%) Balancing Frequently (34-66%) Stooping Occasionally (3-33%) Kneeling Occasionally (3-33%) Crouching Occasionally (3-33%) Crawling Rarely (Less than 2%) Reaching Frequently (34-66%) Gross Manipulation (Handling) Frequently (34-66%) Fine Manipulation (Fingering) Frequently (34-66%) Feeling Constantly (67-100%) Foot Use Rarely (Less than 2%) Vision - Far Constantly (67-100%) Vision - Near Constantly (67-100%) Talking Constantly (67-100%) Hearing Constantly (67-100%) Remote Type Onsite Work Location 221 Longwood Avenue Scheduled Weekly Hours 40 Employee Type Regular Work Shift Day (United States of America) Pay Range $33.46 - $48.66/Hourly Grade 7 At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package. EEO Statement: The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at **************. Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership "looks like" by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.

The Targeted Protein Degradation (TPD) Proteomics Core within the Fischer Lab at Dana-Farber Cancer Institute serves as a resource for the Cancer Biology Department, aiding investigators in answering key research questions using mass spectrometry-based proteomics. We employ quantitative chemoproteomic and interactomic approaches to identify drug targets and are continuing to expand our repertoire to meet the needs of our core users. Our core is equipped with extensive mass spectrometry equipment including tims TOF HT, tims TOF Ultra2 and Orbitrap Eclipse tribrid mass spectrometers. The TPD Core seeks a highly motivated individual to join the team as a RESEARCH SCIENTIST, who will employ mass spectrometry-based technologies to assess the cellular proteome in response to external stimuli. This individual will be an important member of our core team and will work across a variety of different research projects focused on targeted protein degradation as a novel therapeutic modality. While we consider various mass spectrometry related backgrounds, a strong emphasis on **instrument automation, systems management, and proteomics pipeline development** is highly desirable. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world-renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. + Lead the design and execution of proteomics experiments (eg, TMT, DIA, DDA) in collaboration with internal and external investigators + **Develop and implement automated workflows** for sample preparation, instrument scheduling, data acquisition, and analysis across multiple platforms. + **Manage and maintain mass spectrometry instrumentation** **,** including calibration, performance monitoring, and preventive maintenance to ensure high-throughput reliability. + **Integrate laboratory robotics and liquid handling systems** into proteomics sample preparation pipelines to enhance throughput and reproducibility. + Develop, optimize, and troubleshoot sample preparation workflows including whole cell proteomics, interactome analysis, and various enrichment protocols + Analyze data using advanced pipelines (eg, DIA-NN, spectronaut, proteome discoverer) and support biological interpretation. + Train and mentor junior staff and contribute to a culture of continuous improvement + Ensure compliance with lab safety, QC standards, and data integrity policies + Communicates with purchasing and may be responsible for negotiating with vendors + Ph.D in biochemistry, analytical chemistry, bioengineering or related field. + Strong expertise in mass spectrometry-based proteomics and data analysis + Hands on experience operating Thermo and/or Bruker mass spectrometers is required + Demonstrated experience with **laboratory automation, robotics, or pipeline development** (e.g., Hamilton, Opentrons, or custom scripting for workflow automation). + Proficiency with quantitative proteomics (label-free, TMT, DIA) and enrichment techniques. + Familiarity with **data analysis software and scripting** (DIA-NN, Proteome Discoverer, R, Python). + Excellent organizational, troubleshooting, and communication skills. + Proven ability to work collaboratively across interdisciplinary teams and manage multiple projects simultaneously. **Pay Transparency Statement** The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications. For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA) $74,600 - $82,900 At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply. Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law. **EEOC Poster**

Site: The General Hospital Corporation Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. Job Summary How to Apply: Interested candidates should send their CV and cover letter to Zhi Yu at ******************** or ********************** Yu Lab at MGH and the Broad Institute of MIT and Harvard is seeking a motivated and creative Postdoctoral Fellow to join our team (*************************** Our lab focuses on developing and applying computational and statistical methods to multi-omics and other multi-modal data (including genomics, transcriptomes, proteomics, medical imaging, clinical data, and lifestyle data) to examine the mechanisms and potential interventions for cardiovascular and other age-related diseases. We aim to develop personalized strategies for disease prevention and treatment. Qualifications How to Apply: Interested candidates should send their CV and cover letter to Zhi Yu at ******************** or ********************** Research Areas & Responsibilities: The successful candidate will use their strong computational expertise to lead projects in one or more of our key research areas, depending on interest and expertise: * Clonal Hematopoiesis & Age-related Disease: We are passionate about understanding the biology of aging. This research area focuses on how age-related somatic mutations, particularly clonal hematopoiesis (CH), contribute to disease. We believe understanding and intervening in these processes is one of the most important questions for our society. * Machine Learning & Multi-modal Data: We are also working on leverage machine learning to extract information from imaging and clinical notes and further integrate with omics data to discover novel biological insights and perform risk prediction. * Multi-omics Methods Development: While we apply multi-omics data to many questions, we would love to tackle fundamental methodological challenges within the data itself (e.g., discordance between proteomics platforms). We are highly motivated to develop methods that make these measurements more robust, harmonized, and interpretable. Qualifications: * A Ph.D. (or expected Ph.D.) in a quantitative field such as Biostatistics, Bioinformatics, Computational Biology, Electrical or Biomedical Engineering, Genetic Epidemiology, or related discipline. * Strong computational and programming skills are essential (e.g., R or Python). * Demonstrated experience in analyzing large-scale, complex datasets. * First-authored publication(s) demonstrating scientific rigor and creativity. Please Note: A background in biology or prior experience with omics data is not a requirement. As the field evolves rapidly, we welcome candidates with relevant but non-overlapping skill sets who are willing to adapt and learn, so we can grow together. Additional Job Details (if applicable) What We Offer: * A strong commitment to mentorship and career development. The group has a robust publication record, and we are dedicated to helping you build yours. For postdocs aiming for academia, we provide active support for grant applications (e.g., K99/R00) to ensure you are a strong candidate on the job market. * Access to rich, large-scale data, in terms of both the number of cohorts and data types. * Mentorship opportunities. You will have the chance to mentor a number of talented junior students (who are lovely to work with), helping you gain valuable mentoring experience while expanding your own publication record. * A world-class research environment. Of course - this is Boston : ) * A competitive salary compared to similar roles. * We welcome you to chat with our current members to learn more about the group. How to Apply: Interested candidates should send the following materials to Zhi at ******************** or ********************** Remote Type Hybrid Work Location 100 Cambridge Street EEO Statement: The General Hospital Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at **************. Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership "looks like" by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.

Site: The General Hospital Corporation Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. Job Summary We are looking for a postdoctoral fellow to join Dr. Suter's Pulmonary Optical Imaging Laboratory at the Massachusetts General Hospital within the Division of Pulmonary and Critical Care Medicine. A Harvard Medical School appointment will be at the postdoctoral rank. The successful candidate will divide their time between the MGH lab and Harvard University's Center for Nanoscale Systems (CNS), a world-class nanoscale fabrication facility located on the Harvard University campus. The position will involve the design and fabrication of flat optics using lithographic techniques, and the integration of these optics into endoscopic, fiber-based imaging probes. Motivated candidates will ultimately be able to train others on established fabrication processes, resulting in increased opportunity for mentoring and higher-level research and design. Candidates without previous experience in lithographic processing should be strongly motivated and capable of independent learning. Qualifications Required: * A doctorate degree in Engineering, Physics, or related discipline. * Experience with optics and optical systems. The ideal candidate possesses experience or skills related to: * Nanofabrication and/or lithographic processing * Modeling software for optics and optical systems (FDTD, ray tracing, CAD) * Optical fiber * Scientific paper writing The candidate should also be: * Comfortable handling and manipulating sub-millimeter scale optical elements * Self-motivated * Capable of working effectively both independently and as part of a team * Willing and eager to learn new skills and explore novel ideas The Suter Lab is a well-funded but smaller lab, and candidates who are both versatile and motivated will find significant opportunity for growth and increased responsibility. Interested candidates should send their detailed curriculum vitae, a cover letter describing relevant training and research experience, and the names and contact information of three referees to Dr. David Adams, PhD at ***********************. Please reference the position you are applying for in the subject line. Additional Job Details (if applicable) Remote Type Onsite Work Location 55 Fruit Street EEO Statement: The General Hospital Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at **************. Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership "looks like" by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.

Site: The General Hospital Corporation Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. Job Summary We are looking for a postdoctoral fellow to join Dr. Suter's Pulmonary Optical Imaging Laboratory at the Massachusetts General Hospital within the Division of Pulmonary and Critical Care Medicine. A Harvard Medical School appointment will be at the postdoctoral rank. The successful candidate will work within a highly collaborative research environment focused on the development and use of optical diagnostics for studying the lungs. The position will involve the use of novel optical imaging systems including polarization-sensitive optical coherence tomography to assess lung disease. Candidates will be required to conduct preclinical and clinical studies. Qualifications Required: * A doctorate degree in Biomedical Engineering, Electrical Engineering, Physics, or related discipline. * Experience with optics and optical systems. The ideal candidate possesses experience or skills related to: * Biomedical imaging * Image Analysis * Data Processing & Analysis * Programming (Matlab, C/C++, Python) * Optical fiber * Scientific paper writing The candidate should also be: * Self-motivated * Capable of working effectively both independently and as part of a team * Willing and eager to learn new skills and explore novel ideas The Suter Lab is a well-funded but smaller lab, and candidates who are both versatile and motivated will find significant opportunity for growth and increased responsibility. Interested candidates should send their detailed curriculum vitae, a cover letter describing relevant training and research experience, and the names and contact information of three referees to Dr. David Adams, PhD at ***********************. Please reference the position you are applying for in the subject line. Additional Job Details (if applicable) Remote Type Onsite Work Location 55 Fruit Street EEO Statement: The General Hospital Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at **************. Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership "looks like" by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.

Site: The Spaulding Rehabilitation Hospital Corporation Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. Job Summary At Spaulding, we aim to apply research results and new ideas to patient care as quickly as possible. As the principal teaching hospital of the Harvard Medical School Department of Physical Medicine & Rehabilitation, new ideas and a passion for innovation are part of our makeup. This academic affiliation and combined resources allow us to maintain a vigorous research agenda and operate ongoing clinical trials. These and other endeavors enhance Spaulding's treatment programs, with clinical research results that often quickly find their way to the bedside. The post-doctoral fellowship is within the INSPIRE lab at Spaulding Rehabilitation Hospital. The fellow will actively study the neuromechanics of whole limb movements in able-bodied persons and persons with spinal cord injury (SCI). Our research team examines the enduring effects of novel treatments on the neuromechanics of limb movements after SCI through rigorous experimentation, electrophysiology, and modeling. The successful candidate will have a strong background in one or more of the following areas: neuroscience, rehabilitation, and/or engineering. Strong quantitative and experimental skills are required. The position is available for up to one year, with an option to renew this training provided adequate progress is made and the project funding is continued. The work will be conducted in a highly interdisciplinary research environment composed of physiologists, clinicians, neuroscientists, and engineers. In addition to our primary research program, there will be several opportunities to interact and collaborate with faculty in the Harvard Medical School, Massachusetts General Hospital, MIT, and Spaulding Rehabilitation Hospital. The Postdoctoral Research Fellow position is time-limited. It is intended to be a short-term training position, followed by a move to an independent investigator or research career position. The maximum term of service for a Research Fellow appointment is five (5) years. Qualifications Key Responsibilities * Conduct research in the field of physical rehabilitation * Collects, record, analyze and present data * Maintains research records and databases * Conduct literature searches * Assists with recruiting patients for clinical trials * Obtains patient study data from medical records, physicians, etc. * Uses software programs to generate graphs and reports * Prepares reports of completed projects for publication in technical journals, presentations at professional meetings/conferences, and for use in further applied or theoretical research activities. * Participates in manuscript writing for publication in scientific journals and/or for presentations * Performs administrative support duties as required * Draft grants and portions of grants for submission to federal and private agencies with the assistance of the lab director * Works under general supervision * Stay current in area of research interest through review of the relevant literature; educate self about the latest methods and evidence related to physiologic, cardiovascular, and biomedical science * Prepare clinical research protocols and documents for submission to IRB * Assists with recruiting participants for clinical trials * Conduct clinical research following all institution, state, and federal regulations. * Collect research data from participants * Obtains participant study data from medical records, physicians, etc. Lab Specific functions and requirements: * Under the supervision of Randy Trumbower, PT, PhD the candidate should have * Post-doctoral role is performed per established guidelines. * Activities are completed commensurate with technical skills and expertise that were agreed upon at hire. * Scientific posters, presentations and publications are completed to meet established goals. * Lab and institutional representation are consistent with laboratory aims and SRN mission. * Work practices are compliant with funding requirements and regulations. * Project budget is monitored to meet financial targets. * Uphold the PCC Organizational Values of Innovation, Collaboration, Accountability, Respect, and Excellence. Education/Degree Required * Ph.D. or equivalent terminal degree in their field of study. Experience Required * Neurologic rehabilitation research * Publication in clinical research Skills * Expertise in clinical and/or neuromechanical assessment of human limb movements * CPR certification Required * Excellent interpersonal and organizational skills * Confident, articulate, and professional communication skills * The ability to efficiently & professionally communicate, in English (oral & written) * Strong expertise in rehabilitation research * Knowledge of clinical research protocols * Careful attention to details Additional Job Details (if applicable) Remote Type Onsite Work Location 300 First Avenue Scheduled Weekly Hours 40 Employee Type Regular Work Shift Day (United States of America) EEO Statement: The Spaulding Rehabilitation Hospital Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at **************. Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership "looks like" by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.

Pre-clinical group developing next generation antibody and CAR T cell immunotherapies for cancer is looking for an exceptionally motivated individual with past in vivo experience. The Smith Lab group is focused CAR T cell immunotherapy for cancer and protein engineering/synthetic biology; taking projects from conception to transgene design /genetic engineering, through reduction to practice, and into in vivo studies, and ultimately to the clinic. >10 clinical trials have launched stemming from the Smith team's pre-clinical work. The candidate will make substantial contributions to the leadership of our in vivo work among other contributions. This will include coordinating and advising other senior staff in the lab in terms of design and timelines for in vivo experimentation, planning, execution, and data analysis. The candidate is expected to partner with others in the lab to lead many of the ongoing and future in vivo efforts including hands on tail vein injections and other procedures, as well as liaisoning/coordinating with the DFCI Animal Research Facility and technicians to ensure efficient, robust, accurate, ethical, and thoughtful in vivo work of the group. We expect a strong background in some of the laboratory methods required to perform this primary in vivo responsibilities, leadership responsibilities, and additional cell culture lab bench work. We provide training to expand the scientist's took box in terms of CAR T cell and cancer immunotherapy workflows. Additional opportunities for growth are attending lectures and journal clubs held here at DFCI and participating in academic and industry collaborations. The work is highly translational and there is a clear path to moving to the clinic candidates based on this work. The applicant will have ample opportunity to design, conduct, and work with CROs to support in vivo IND enabling studies. Dr. Smith is deeply committed to the success of each trainee that joins the lab. He believes that mentorship should be intentional, thought out, and personalized for each member of the group. He dedicates time to meet trainees' individual needs for scientific growth and pursuit of their career goals. We are looking for an enthusiastic, self-motivated, independent thinker with a tremendous communication skills and work ethic. The position will require great planning and organizational skills. An ability to work well with others as part of a cohesive team, take initiative, and creatively problem solve are a must. The Dana-Farber Cancer Institute brings together world-renowned clinicians, innovative researchers and dedicated professionals, allied in the common mission of conquering cancer. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to all patients; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. This **full-time in person bench science position will include project-specific and general lab responsibilities as outlined below:** + Operational leadership and organization of in vivo experiments across the lab. + Carry out in vivo experiments including tail vein injections + Analyze experimental data and interpret results. + Maintain detailed electronic notebook of all experiments. + Exercise judgment in selecting methods, techniques and evaluation criteria for obtaining results. + Generate data of a quality upon which decisions for the future direction of a program can be based. + Write reports and summaries of findings. + Participate in formal and information presentations. + Intellectual commitment to position by keeping up with appropriate literature and research publications. + Contribute to technical reports, the grant application process and manuscript preparation as required. + Development, improvement and adherence to standard operating procedures. + Proactive and reliable stewardship of the laboratory. + May coordinate activities of other staff + Acts independently to determine methods and procedures + Collaborate and coordinate with team members across groups and functions + PhD or equivalent. Masters with substantial experience in in vivo experimentation and leadership will be considered + Deep prior experience with in vivo murine experimentation including expertise in tail vein injections and other standard procedures + Exceptionally self-motivated and eager to expand existing skill + Must have excellent communication skills (written and verbal) + Builds stable working relationships; be able to work with a wide variety of faculty and staff + Outstanding organization; detail oriented; multi-tasking skills + Must consider attention to detail a strength + Outstanding planning, organizational, multi-tasking skills + Ability to work within a team environment **Pay Transparency Statement** The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications. For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA) $92,400 - $104,300 Only applicants that submit a cover letter, detailed CV will be considered. As part of the selection process the contact information for three references will be requested. Faculty Director: Eric Smith, MD PhD (*************************************** At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply. Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law. **EEOC Poster**

Pre-clinical group developing next generation antibody and CAR T cell immunotherapies for cancer is looking for an exceptionally motivated individual with past in vivo experience. The Smith Lab group is focused CAR T cell immunotherapy for cancer and protein engineering/synthetic biology; taking projects from conception to transgene design /genetic engineering, through reduction to practice, and into in vivo studies, and ultimately to the clinic. >10 clinical trials have launched stemming from the Smith team's pre-clinical work. The candidate will make substantial contributions to the leadership of our in vivo work among other contributions. This will include coordinating and advising other senior staff in the lab in terms of design and timelines for in vivo experimentation, planning, execution, and data analysis. The candidate is expected to partner with others in the lab to lead many of the ongoing and future in vivo efforts including hands on tail vein injections and other procedures, as well as liaisoning/coordinating with the DFCI Animal Research Facility and technicians to ensure efficient, robust, accurate, ethical, and thoughtful in vivo work of the group. We expect a strong background in some of the laboratory methods required to perform this primary in vivo responsibilities, leadership responsibilities, and additional cell culture lab bench work. We provide training to expand the scientist's took box in terms of CAR T cell and cancer immunotherapy workflows. Additional opportunities for growth are attending lectures and journal clubs held here at DFCI and participating in academic and industry collaborations. The work is highly translational and there is a clear path to moving to the clinic candidates based on this work. The applicant will have ample opportunity to design, conduct, and work with CROs to support in vivo IND enabling studies. Dr. Smith is deeply committed to the success of each trainee that joins the lab. He believes that mentorship should be intentional, thought out, and personalized for each member of the group. He dedicates time to meet trainees' individual needs for scientific growth and pursuit of their career goals. We are looking for an enthusiastic, self-motivated, independent thinker with a tremendous communication skills and work ethic. The position will require great planning and organizational skills. An ability to work well with others as part of a cohesive team, take initiative, and creatively problem solve are a must. The Dana-Farber Cancer Institute brings together world-renowned clinicians, innovative researchers and dedicated professionals, allied in the common mission of conquering cancer. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to all patients; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. Responsibilities This full-time in person bench science position will include project-specific and general lab responsibilities as outlined below: * Operational leadership and organization of in vivo experiments across the lab. * Carry out in vivo experiments including tail vein injections * Analyze experimental data and interpret results. * Maintain detailed electronic notebook of all experiments. * Exercise judgment in selecting methods, techniques and evaluation criteria for obtaining results. * Generate data of a quality upon which decisions for the future direction of a program can be based. * Write reports and summaries of findings. * Participate in formal and information presentations. * Intellectual commitment to position by keeping up with appropriate literature and research publications. * Contribute to technical reports, the grant application process and manuscript preparation as required. * Development, improvement and adherence to standard operating procedures. * Proactive and reliable stewardship of the laboratory. * May coordinate activities of other staff * Acts independently to determine methods and procedures * Collaborate and coordinate with team members across groups and functions Qualifications * PhD or equivalent. Masters with substantial experience in in vivo experimentation and leadership will be considered * Deep prior experience with in vivo murine experimentation including expertise in tail vein injections and other standard procedures * Exceptionally self-motivated and eager to expand existing skill * Must have excellent communication skills (written and verbal) * Builds stable working relationships; be able to work with a wide variety of faculty and staff * Outstanding organization; detail oriented; multi-tasking skills * Must consider attention to detail a strength * Outstanding planning, organizational, multi-tasking skills * Ability to work within a team environment Pay Transparency Statement The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications. For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA) $92,400 - $104,300 Only applicants that submit a cover letter, detailed CV will be considered. As part of the selection process the contact information for three references will be requested. Faculty Director: Eric Smith, MD PhD (*************************************** At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply. Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law. EEOC Poster

Dana-Farber Cancer Institute (DFCI) is seeking a highly motivated Pre-Clinical Scientist to support the research activities at the Experimental Therapeutics (ETx) Core and the Lurie Family Imaging Center (LFIC). The ETx Core and LFIC are co-located in a state-of-the-art 14,000 square-foot preclinical facility, fully equipped with housing and procedure rooms, as well as a suite of in vivo imaging scanners. The Pre-Clinical Scientist will integrate with a highly skilled team of Scientists and Research Associates, and report directly to the Director. The in vivo studies conducted at the facility are focused on cancer research, with an emphasis on in vivo pharmacology, the assessment of novel cancer therapeutics, and multimodality imaging of cancer, and provide key information for the improvement of cancer patient treatment and care. The position is at 27 Dry Dock Ave, South Boston ****************************** Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. The successful candidate will work collaboratively and in concert with a staff of dedicated scientists, animal/imaging technologists/associates, administrative personnel, and clinical counterparts to design and execute oncology related mouse studies using various imaging modalities (BLI/MRI/SPECT/PET/CT, etc) as well as the entire spectrum of conventional (e.g., caliper measurements, clinical scoring) endpoints to evaluate pre-clinical novel cancer therapies. The Pre-Clinical Scientist will work closely with the Director to execute the vision and strategic direction of translational cancer research. The Pre-Clinical Scientist will partner with clinical affiliates to facilitate bidirectional translational cancer science. The Pre-Clinical Scientist will work closely with other Centers and Departments at Dana-Farber that are engaged in research on small animal modeling in cancer and in experimental therapeutics. The Scientist will be expected to develop research projects for presentation at national meetings and publication in peer-reviewed journals. The Pre-Clinical Scientist will build collaborations with principal investigators, other departments, and industrial partners to design experimental therapeutics studies, and will be responsible for the execution, analysis and generation of reports for studies. **Skills and Abilities Required** + Hands-on experience using various cell line and PDX mouse/rat models and orthotopic models to execute in vivo workflows is highly desired. + Familiar with IVIS, PET/CT, MRI and other imaging approaches. + Demonstrated ability to deploy novel in vivo models to enable drug discovery and translational research. + Excellent interpersonal and communication skills with the ability to interact effectively with internal and external collaborators. + Demonstrated expertise in various in vitro methodologies such as immune profiling by flow cytometry, ELISA and Western blot analysis. + Ability to establish independent research and secure external funding + Full-time, M-F; hours may vary with project needs Dana-Farber Cancer Institute supports a robust Scientist career track with multiple opportunities for advancement, leadership, and recognition. The successful candidate will be appointed to a level within the Scientist career track commensurate with his or her accomplishments and abilities. Promotion on this track will be based on achievement of goals. + PhD cancer biology, biology or relevant biological sciences + Minimum of 5 years' experience in pre-clinical pharmacology pre- or post-PhD + Established track record of research publications, preferably in cancer research + Builds productive internal/external working relationships. + Having wide-ranging experience, uses technical concepts and Institute objectives to resolve complex issues in creative and effective ways. + Works on complex issues where analysis of situations or data requires an in-depth evaluation of variable factors. + Exercises judgment in selecting methods, techniques and evaluation criteria for obtaining results. + Networks with key contacts outside our own area of expertise. **Pay Transparency Statement** The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications. For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA) $80,000 - $82,900 At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply. Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law. **EEOC Poster**

Dana-Farber Cancer Institute (DFCI) is seeking a highly motivated Pre-Clinical Scientist to support the research activities at the Experimental Therapeutics (ETx) Core and the Lurie Family Imaging Center (LFIC). The ETx Core and LFIC are co-located in a state-of-the-art 14,000 square-foot preclinical facility, fully equipped with housing and procedure rooms, as well as a suite of in vivo imaging scanners. The Pre-Clinical Scientist will integrate with a highly skilled team of Scientists and Research Associates, and report directly to the Director. The in vivo studies conducted at the facility are focused on cancer research, with an emphasis on in vivo pharmacology, the assessment of novel cancer therapeutics, and multimodality imaging of cancer, and provide key information for the improvement of cancer patient treatment and care. The position is at 27 Dry Dock Ave, South Boston ****************************** Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. Responsibilities The successful candidate will work collaboratively and in concert with a staff of dedicated scientists, animal/imaging technologists/associates, administrative personnel, and clinical counterparts to design and execute oncology related mouse studies using various imaging modalities (BLI/MRI/SPECT/PET/CT, etc) as well as the entire spectrum of conventional (e.g., caliper measurements, clinical scoring) endpoints to evaluate pre-clinical novel cancer therapies. The Pre-Clinical Scientist will work closely with the Director to execute the vision and strategic direction of translational cancer research. The Pre-Clinical Scientist will partner with clinical affiliates to facilitate bidirectional translational cancer science. The Pre-Clinical Scientist will work closely with other Centers and Departments at Dana-Farber that are engaged in research on small animal modeling in cancer and in experimental therapeutics. The Scientist will be expected to develop research projects for presentation at national meetings and publication in peer-reviewed journals. The Pre-Clinical Scientist will build collaborations with principal investigators, other departments, and industrial partners to design experimental therapeutics studies, and will be responsible for the execution, analysis and generation of reports for studies. Skills and Abilities Required * Hands-on experience using various cell line and PDX mouse/rat models and orthotopic models to execute in vivo workflows is highly desired. * Familiar with IVIS, PET/CT, MRI and other imaging approaches. * Demonstrated ability to deploy novel in vivo models to enable drug discovery and translational research. * Excellent interpersonal and communication skills with the ability to interact effectively with internal and external collaborators. * Demonstrated expertise in various in vitro methodologies such as immune profiling by flow cytometry, ELISA and Western blot analysis. * Ability to establish independent research and secure external funding * Full-time, M-F; hours may vary with project needs Dana-Farber Cancer Institute supports a robust Scientist career track with multiple opportunities for advancement, leadership, and recognition. The successful candidate will be appointed to a level within the Scientist career track commensurate with his or her accomplishments and abilities. Promotion on this track will be based on achievement of goals. Qualifications * PhD cancer biology, biology or relevant biological sciences * Minimum of 5 years' experience in pre-clinical pharmacology pre- or post-PhD * Established track record of research publications, preferably in cancer research * Builds productive internal/external working relationships. * Having wide-ranging experience, uses technical concepts and Institute objectives to resolve complex issues in creative and effective ways. * Works on complex issues where analysis of situations or data requires an in-depth evaluation of variable factors. * Exercises judgment in selecting methods, techniques and evaluation criteria for obtaining results. * Networks with key contacts outside our own area of expertise. Pay Transparency Statement The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications. For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA) $80,000 - $82,900 At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply. Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law. EEOC Poster

The Dana-Farber Cancer Institute seeks a Laboratory Scientist to focus on next-generation, translational pathology studies who will work within the Wolpin-Nowak laboratory (********************************************** as part of the Hale Family Center for Pancreatic Cancer Research (**************************************** and the Lustgarten Foundation Pancreatic Cancer Research Laboratory at the Dana-Farber Cancer institute. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. Our research group investigates the biology and risk factors associated with pancreatic and other gastrointestinal cancers. We aim to improve outcomes for patients with these diseases both by identifying cancer earlier, when the chance for a cure is greater, and by improving therapy. We focus on learning from cancer patients by studying human biospecimens so that our discoveries can be rapidly and confidently translated into improved clinical care. Our laboratory members include epidemiologists, biostatisticians, pathologists, data scientists, molecular biologists, and clinical researchers, all of whom contribute their unique expertise to our lab's work. We employ a broad variety of analysis approaches and techniques in our laboratory, including population-scale epidemiology studies, digital pathology, genomic sequencing, and spatial transcriptomic and protein profiling. Our tissue profiling work encompasses both clinical trial correlative studies and landscape-directed discovery studies. We work closely with the Gastrointestinal Cancer Center Biobank to acquire blood, tissue, and other sample types from patients at Dana-Farber Cancer Institute. Finally, we routinely collaborate both with investigators at Dana-Farber and across the nation to study pancreatic cancer using model systems and to conduct and lead clinical trials. + Design and conduct studies using multiplex immunofluorescence, spatial transcriptional profiling, and other cutting edge, high-dimension tissue analysis approaches to evaluate pancreatic cancer pathology using human tissue specimens + Collaborate with other laboratory members with expertise in pathology, molecular biology, and epidemiology/ biostatistics + Mentor and supervise research technicians performing tissue-based analyses + Serve as a liaison for collaborations with other laboratories and institutions + Maintain laboratory protocol databases, patient tissue and slide archives, and digital assets + Oversee and maintain laboratory infrastructure + Assist in training new postdoctoral fellows and research technicians + Conduct analyses using digital image processing software, such as in Form and QuPath, and statistical packages such as R and SAS + Participate in group meetings and work collaboratively on larger projects with other group members + Generate data for figures and tables to serve as the basis for published manuscripts + Contribute to manuscripts describing research results + Contribute to progress reports related to research funding KNOWLEDGE, SKILLS AND ABILITIES REQUIRED + Strong background in human pathology + Experience with traditional pathology laboratory techniques, including slide sectioning, H&E staining, immunohistochemistry and special stains a plus + Experience with translational pathology techniques, including multiplexed immunofluorescence, spatial transcriptomics, and RNA in situ hybridization a plus + Experience in oncology research would be an advantage + Strong commitment to cancer research is required + Experience managing laboratory staff would be an advantage + Ability to work independently and perform troubleshooting when needed + Must have excellent communication skills (written and verbal) and work with a wide variety of faculty and staff. + Ability to analyze information and use logic to address work-related issues and problems + Attention to detail and thoroughness in completing work tasks + Outstanding organizational skills and excellent record keeping + Ability to thrive in a fast-paced, team-oriented environment with a shared mission to advance cancer biology + Ability to manage multiple projects simultaneously + Doctoral degree in genetics/genomics, cancer biology, pathology or related fields + MD or MD-equivalent and PhD-holding candidates will both be considered; MD/PhD-holding candidates with pathology training are highly encouraged to apply + Multidisciplinary training and experience in multiple of these fields is desirable + One or more years of postdoctoral research experience (or equivalent) in academia or industry required **Pay Transparency Statement** The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications. For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA) $74,600 - $82,900 At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply. Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law. **EEOC Poster**

The Dana-Farber Cancer Institute seeks a Laboratory Scientist to focus on next-generation, translational pathology studies who will work within the Wolpin-Nowak laboratory (********************************************** as part of the Hale Family Center for Pancreatic Cancer Research (**************************************** and the Lustgarten Foundation Pancreatic Cancer Research Laboratory at the Dana-Farber Cancer institute. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. Responsibilities Our research group investigates the biology and risk factors associated with pancreatic and other gastrointestinal cancers. We aim to improve outcomes for patients with these diseases both by identifying cancer earlier, when the chance for a cure is greater, and by improving therapy. We focus on learning from cancer patients by studying human biospecimens so that our discoveries can be rapidly and confidently translated into improved clinical care. Our laboratory members include epidemiologists, biostatisticians, pathologists, data scientists, molecular biologists, and clinical researchers, all of whom contribute their unique expertise to our lab's work. We employ a broad variety of analysis approaches and techniques in our laboratory, including population-scale epidemiology studies, digital pathology, genomic sequencing, and spatial transcriptomic and protein profiling. Our tissue profiling work encompasses both clinical trial correlative studies and landscape-directed discovery studies. We work closely with the Gastrointestinal Cancer Center Biobank to acquire blood, tissue, and other sample types from patients at Dana-Farber Cancer Institute. Finally, we routinely collaborate both with investigators at Dana-Farber and across the nation to study pancreatic cancer using model systems and to conduct and lead clinical trials. * Design and conduct studies using multiplex immunofluorescence, spatial transcriptional profiling, and other cutting edge, high-dimension tissue analysis approaches to evaluate pancreatic cancer pathology using human tissue specimens * Collaborate with other laboratory members with expertise in pathology, molecular biology, and epidemiology/ biostatistics * Mentor and supervise research technicians performing tissue-based analyses * Serve as a liaison for collaborations with other laboratories and institutions * Maintain laboratory protocol databases, patient tissue and slide archives, and digital assets * Oversee and maintain laboratory infrastructure * Assist in training new postdoctoral fellows and research technicians * Conduct analyses using digital image processing software, such as in Form and QuPath, and statistical packages such as R and SAS * Participate in group meetings and work collaboratively on larger projects with other group members * Generate data for figures and tables to serve as the basis for published manuscripts * Contribute to manuscripts describing research results * Contribute to progress reports related to research funding KNOWLEDGE, SKILLS AND ABILITIES REQUIRED * Strong background in human pathology * Experience with traditional pathology laboratory techniques, including slide sectioning, H&E staining, immunohistochemistry and special stains a plus * Experience with translational pathology techniques, including multiplexed immunofluorescence, spatial transcriptomics, and RNA in situ hybridization a plus * Experience in oncology research would be an advantage * Strong commitment to cancer research is required * Experience managing laboratory staff would be an advantage * Ability to work independently and perform troubleshooting when needed * Must have excellent communication skills (written and verbal) and work with a wide variety of faculty and staff. * Ability to analyze information and use logic to address work-related issues and problems * Attention to detail and thoroughness in completing work tasks * Outstanding organizational skills and excellent record keeping * Ability to thrive in a fast-paced, team-oriented environment with a shared mission to advance cancer biology * Ability to manage multiple projects simultaneously Qualifications * Doctoral degree in genetics/genomics, cancer biology, pathology or related fields * MD or MD-equivalent and PhD-holding candidates will both be considered; MD/PhD-holding candidates with pathology training are highly encouraged to apply * Multidisciplinary training and experience in multiple of these fields is desirable * One or more years of postdoctoral research experience (or equivalent) in academia or industry required Pay Transparency Statement The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications. For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA) $74,600 - $82,900 At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply. Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law. EEOC Poster

Program: The Fellowship will provide a two-year mentored training experience in research focused on cancer health policy at Dana-Farber Cancer Institute (DFCI) and Beth Israel-Deaconess Medical Center (BIDMC), which are both Harvard Medical School teaching hospitals. This unique program brings together expertise in cancer care delivery research (Dana-Farber's Center for Outcomes and Policy Research), along other Population Sciences pillars (DFCI's cancer genetics, health communication, clinical computational oncology), and health policy (BIDMC's Health Policy Section at the Smith Center for Outcomes Research), providing an exceptional environment for postdoctoral fellows to develop and carry out research at the intersection of oncology and health policy under shared mentorship between these programs. Goal: To develop the next generation of leaders in oncology and health policy by providing rigorous training in the use of big data, advanced biostatistical methods, and econometric approaches, paired with dedicated mentorship from experts to advance innovative, high-impact research. A two-year joint post-doctoral training program between the Division of Population Sciences at Dana-Farber Cancer Institute and the Richard A. and Susan F. Smith Center for Outcomes Research at Beth Israel Deaconess Medical Center. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. Responsibilities * Post-doctoral fellows will spend two years (starting July 2026) conducting mentored research. * The fellow will be housed within the Division of Population Sciences at Dana-Farber Cancer Institute (DFCI) in Boston, Massachusetts, which will provide space, salary support, the support of an experienced mentor in the Division, and opportunity to participate in seminars on cancer care delivery research, genetics and prevention, and/or clinical computational oncology. * The fellow will also receive joint mentorship and training at the Smith Center for Outcomes Research (BIDMC), including support of an experienced mentor in health policy, participation in seminars focused on health policy and statistical methods for causal inference, access to diverse national data sources, and analytic support. * Based on interests identified at the time of application, the fellow will be guided toward appropriate mentors who will provide research oversight and supervision. * The mentors will work closely with the fellow to refine research questions, develop study designs, and create rigorous analytic plans. * They will provide ongoing guidance to fellows to ensure successful execution of the research and will actively support dissemination of research findings through talks and publications. * During the two-year fellowship, we will encourage submission of a K series or other career development award to ensure a successful transition to an independent faculty position upon completion of the program. Faculty Co-Directors:Jennifer Mack, MD MPH, Director of the Center for Outcomes and Policy Research and Associate Chief of the Division of Population Sciences, DFCIRishi Wadhera, MD, MPP, MPhil, Director of the Health Policy Section of the Richard A. and Susan F. Smith Center for Outcomes Research, BIDMC Funding:Salary is supported by the McGraw/Patterson fund in the Division of Population Sciences at Dana-Farber Cancer Institute. Interested applicants should send the following to Nicole Santangelo (Nicole_***************************) by December 12, 2025: * A completed application * Curriculum vitae * 2-3 letters of professional recommendation, submitted directly to Nicole Santangelo at the address above * A one-page statement describing professional background and training to date (Arial 11-point font, single spaced, 1 inch margins) * A one-page statement describing research interests, career goals, and interest in the fellowship (Arial 11-point font, single spaced, 1 inch margins) Qualifications * Applicants must have completed a Ph.D. or M.D. degree in medicine, public health, or a related field in order to apply (or have an anticipated degree by July 2026) * Applicants may be in a clinical field (eg, medicine, nursing) or a non-clinical discipline (eg, health policy, economics, social sciences). * Applicants from a clinical field should have training in a field relevant to cancer health policy. Pay Transparency Statement The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications. For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA) $72,000 - $76,385 At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are committed to having faculty and staff who offer multifaceted experiences. Cancer knows no boundaries and when it comes to hiring the most dedicated and compassionate professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply. Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law. EEOC Poster

Program: The Fellowship will provide a two-year mentored training experience in research focused on cancer health policy at Dana-Farber Cancer Institute (DFCI) and Beth Israel-Deaconess Medical Center (BIDMC), which are both Harvard Medical School teaching hospitals. This unique program brings together expertise in cancer care delivery research (Dana-Farber's Center for Outcomes and Policy Research), along other Population Sciences pillars (DFCI's cancer genetics, health communication, clinical computational oncology), and health policy (BIDMC's Health Policy Section at the Smith Center for Outcomes Research), providing an exceptional environment for postdoctoral fellows to develop and carry out research at the intersection of oncology and health policy under shared mentorship between these programs. Goal: To develop the next generation of leaders in oncology and health policy by providing rigorous training in the use of big data, advanced biostatistical methods, and econometric approaches, paired with dedicated mentorship from experts to advance innovative, high-impact research. A two-year joint post-doctoral training program between the Division of Population Sciences at Dana-Farber Cancer Institute and the Richard A. and Susan F. Smith Center for Outcomes Research at Beth Israel Deaconess Medical Center. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. + Post-doctoral fellows will spend two years (starting July 2026) conducting mentored research. + The fellow will be housed within the Division of Population Sciences at Dana-Farber Cancer Institute (DFCI) in Boston, Massachusetts, which will provide space, salary support, the support of an experienced mentor in the Division, and opportunity to participate in seminars on cancer care delivery research, genetics and prevention, and/or clinical computational oncology. + The fellow will also receive joint mentorship and training at the Smith Center for Outcomes Research (BIDMC), including support of an experienced mentor in health policy, participation in seminars focused on health policy and statistical methods for causal inference, access to diverse national data sources, and analytic support. + Based on interests identified at the time of application, the fellow will be guided toward appropriate mentors who will provide research oversight and supervision. + The mentors will work closely with the fellow to refine research questions, develop study designs, and create rigorous analytic plans. + They will provide ongoing guidance to fellows to ensure successful execution of the research and will actively support dissemination of research findings through talks and publications. + During the two-year fellowship, we will encourage submission of a K series or other career development award to ensure a successful transition to an independent faculty position upon completion of the program. Faculty Co-Directors: Jennifer Mack, MD MPH, Director of the Center for Outcomes and Policy Research and Associate Chief of the Division of Population Sciences, DFCI Rishi Wadhera, MD, MPP, MPhil, Director of the Health Policy Section of the Richard A. and Susan F. Smith Center for Outcomes Research, BIDMC Funding: Salary is supported by the McGraw/Patterson fund in the Division of Population Sciences at Dana-Farber Cancer Institute. **Interested applicants should send the following to Nicole Santangelo (Nicole_***************************) by December 12, 2025:** + A completed application + Curriculum vitae + 2-3 letters of professional recommendation, submitted directly to Nicole Santangelo at the address above + A one-page statement describing professional background and training to date (Arial 11-point font, single spaced, 1 inch margins) + A one-page statement describing research interests, career goals, and interest in the fellowship (Arial 11-point font, single spaced, 1 inch margins) + Applicants must have completed a Ph.D. or M.D. degree in medicine, public health, or a related field in order to apply (or have an anticipated degree by July 2026) + Applicants may be in a clinical field (eg, medicine, nursing) or a non-clinical discipline (eg, health policy, economics, social sciences). + Applicants from a clinical field should have training in a field relevant to cancer health policy. Pay Transparency Statement The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications. For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA) $72,000 - $76,385 At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are committed to having faculty and staff who offer multifaceted experiences. Cancer knows no boundaries and when it comes to hiring the most dedicated and compassionate professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply. Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law. **EEOC Poster**