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DCRI company history timeline

1969

DCRI’s legacy of innovation and impact dates back to 1969 with the Duke Databank for Cardiovascular Disease (DDCD), which ushered in what was at the time a novel, computer-assisted, data-driven approach to generating evidence for cardiovascular clinical research studies.

1976

The DDCD was officially created from the original Databank group in 1976.

1984

1984: Created the first electronic electrocardiogram (eECG) core laboratory

1986

1986: Completed its first multicenter trial (TAMI-1)

1993

1993: Completed its first international trial (GUSTO-I), the largest comparative thrombolytic trial in history at the time

1996

Before the founding of the Duke Clinical Research Institute (DCRI) in 1996, the DDCD made significant contributions to the field of clinical research, including:

2000

Announced ARISTOTLE results—Apixaban safer and more effective than warfarin—later, this study was named to Drazen’s Dozen as one of 12 studies that has most changed clinical practice since 2000

2018

In August 2018, Robert Califf, MD, provided his thoughts on the past and future of the DCRI.

Received a $95 million NIH grant over 7 years for the Pediatric Trials Network (PTN); grant was renewed in 2018; to date, the PTN has contributed to label changes for 15 drugs

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Founded
1969
Company founded
Headquarters
Durham, NC
Company headquarter
Founders
Robert Califf
Company founders
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DCRI competitors

Company nameFounded dateRevenueEmployee sizeJob openings
PRA Health Sciences1976$3.2B17,000-
Chiltern1982$3.1M35-
icon Mechanical1995$8.3B14,600174
Cato Research1988$28.9M200-
Harvard Clinical Research Institute2000$50.0M190-
NSABP Foundation1995$460,00062

DCRI history FAQs

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DCRI may also be known as or be related to DCRI, Duke Clinical Research Institute and Duke Clinical Research institute.