Hoffmann-LA Roche Inc jobs in Carlsbad, CA - 25 jobs

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. The Position As a Maintenance Calibration/Metrology Technician joining our Carlsbad team, you will play a crucial role in leading and supervising a team of calibration technicians. You are ensuring the calibration accuracy and reliability of GenMark's equipment. The Opportunity * Ensure timely completion of calibration activities. Assigning, overseeing, and performing the calibration of a wide range of instruments and equipment. Ensuring all calibration activities comply with company policies and regulatory standards. Developing and maintaining calibration procedures and documentation. Reviewing and approving calibration certificates and records. Investigating and resolving discrepancies or non-conformances * Providing training and guidance to calibration technicians. Assist with on-the-job training of lower-level technicians. Demonstrate awareness of applicable safety guidelines and standards. * Assisting in monitoring and troubleshooting the Temperature Monitoring System and providing technical support for equipment non-conformances. * Equipment validations (IQ/OQ) and documenting all activities following Good Documentation Practice. * Maintaining the Kanban system by updating inventory levels, monitoring card movements, and replenishing stock as needed. Conduct regular audits, identify discrepancies, and implement corrective actions. * Supporting the Manufacturing Engineering group with continuous process improvement projects. Lead special projects as requested and perform additional duties as assigned. Who you are * You bring a High School Diploma or Equivalent; Associate degree or technical/trade school in Engineering or Scientific field preferred * 6-8 years of experience in a regulated manufacturing environment is required. * Asset Database Management system, FDA, cGMPs, and/or ISO, CFR-Part 820 knowledge and experience is required Behaviors, competencies, and qualities of the ideal applicant. * Strong quality orientation with attention to detail and a desire to deliver service excellence is highly desired. Experience using documents and quality control procedures which include best practices * Demonstrated ability to analyze and solve equipment faults issues in both mechanical and electronic systems and provide a root cause. Strong problem-solving, judgment, and decision-making skills. Able to use computer software programs such as Word, and Excel * Experience with automated liquid reagent dispensing systems (Biodot, etc..); with surface modification (plasma, Corona, etc..) and spray coating; with machine vision system (Cognex, Keyence, etc.) is a plus Relocation benefits are not offered for this job posting. The expected salary range for this position, based on the primary location of California is 49,300.00 - 91,500.00 USD Annual. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below. Benefits. Who we are GenMark is now a proud member of the Roche Group, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. As a global leader in healthcare, Roche Diagnostics offers a broad portfolio of products, tools and services that help in the prevention, diagnosis and management of diseases like HPV, HIV, hepatitis and diabetes as well as other medical conditions, such as fertility and blood coagulation. With the addition of GenMark to the Roche Group, syndromic infectious disease diagnostics is now added to the long list of disease states and conditions that the Roche Group addresses. GenMark's ePlex true sample-to-answer system offers unique solutions to address the most significant challenges facing clinical laboratories, while supporting hospital systems to deliver patient-centered, value-based care. ePlex streamlines the diagnostic workflow from physician order entry to the final test report and is the true sample-to-answer solution designed to improve patient care, reduce costs, and increase lab efficiency. GenMark is headquartered in Carlsbad, California. GenMark is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

A global biotechnology company is seeking a Principal Research Scientist in San Diego to focus on targeted drug delivery, particularly nucleic acid therapies. The ideal candidate will have expertise in receptor biology, collaborate with cross-functional teams, and contribute to innovative therapeutic programs. A Ph.D. or equivalent in biology or a related field is required, along with relevant experience of 4-10 years depending on the educational background. #J-18808-Ljbffr

Genentech, Inc. seeks a Business Process Analyst at its Oceanside, CA location. Duties: Contribute to the design and development of solutions and continuous improvement of SAP/MES integration strategy and scenarios for manufacturing sites. Drive the Manufacturing Execution System (MES) integration strategy to align with organizational objectives. Forge strategic partnerships with the MES Program Lead, Product Line Lead, and Product Manager to shape and drive the Global MES Program Strategy. Pioneer innovative pathways with Product Line Leads and Product Managers in the new modalities space, integrating groundbreaking technologies into the Global MES Program Technology landscape. Collaborate with MES Core Teams to enhance the efficiency and effectiveness of MES solution deployment across sites. Lead rigorous testing initiatives, working directly with site teams to ensure the reliability, efficiency, and precision of MES/SAP solutions in alignment with business goals. Optimize SAP configurations, coordinating with master data and functional consultants to tailor data setups and configurations for seamless testing and implementation. Align global processes with strategic vision, partnering with the Global Business Process Harmonization team to ensure MES/SAP solutions adhere to the global Roche template. Deliver actionable insights and innovative guidance on adopting SAP S4/HANA/EWM and MES solutions to elevate site operations. Collaborate with MES integration product teams to rigorously test and enhance the MES-SAP interfaces, ensuring seamless system interoperability and superior functionality. May telecommute up to 3 days per week. Position requires up to 25% fully reimbursed domestic and international travel. Education and experience required: Bachelor's degree, or foreign equivalent, in Engineering or Computer Science or related field and 8 years of experience as Systems Engineer, Business/Systems Analyst, or related position Special Requirements: 3 years of experience must include: Pharmaceutical Manufacturing Processes SAP-MES interfaces Installation and deployment of Pharmasuite and Syncade Solutions Architecture Hands-on SAP Powershell Scripting The expected annual salary range for this position based on the primary location for this position of California is $181,128 to $267,700 per year. Actual pay within the range will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below. Benefits (**************************************************** Worksite: 1 Antibody Way, Bldg. 331, Oceanside, CA 92056 Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. **The Position** The Pharma Technical Operations (PT) department is establishing the One PT Data Office to serve as the strategic center for data governance, strategy, and enablement across the entire global PT network. This team is at the heart of our digital transformation, responsible for architecting and leading a central data office to unlock the full potential of PT's data assets. The Head of PT Data Acceleration will be accountable for establishing this critical function in close collaboration with the Head of PT Data Governance. This role is central to creating a single, unified data strategy that will serve as the backbone for our data driven decision making in PT as well for our digital transformation. You will be at the heart of our transformation, building a world-class data organization to unlock the full potential of PT's data assets. You will build and lead a high-performing team, champion a data-first culture across PT, and ensure that data is managed as a strategic asset to accelerate the realization of patient benefits. This pivotal role requires a visionary leader capable of building a unified data ecosystem, delivering measurable outcomes, and ensuring our data capabilities are a key driver of efficiency, quality, and innovation. **The Opportunity** + Provide strategic leadership and vision for data management across PT, ensuring alignment with PT's digital strategy and Roche's overall data ambitions. + Develop, champion, and execute a comprehensive, long-term data strategy and Data Product roadmap, identifying high-impact opportunities in close partnership with PTx business stakeholders to meet their organizational objectives. + Collaborate with the Head of Data Governance to establish and enforce a robust, centralized data governance framework, including policies, standards, and stewardship practices to ensure the quality, integrity, and security of data across the entire product lifecycle. + Accountable for breaking down data silos and architecting a single, unified data ecosystem for PT that is FAIR (Findable, Accessible, Interoperable, Reusable). + Drive the adoption of cutting-edge technologies and platforms to ensure state of the art data infrastructure, in close collaboration with IT and IT/OT teams. + Build, recruit, develop, and retain a world-class, globally distributed team of data professionals, nurturing their skills in data governance, strategy, and architecture. + Build and maintain strong strategic relationships with key senior stakeholders across PT (e.g., manufacturing, quality, supply chain, development, regulatory), global functions, and IT. + Serve as the ultimate steward of our data, ensuring all data activities are conducted in compliance with GxP, GDPR, and other relevant regulations, thereby building trust with all stakeholders. + Define, track, and report on the tangible business value, ROI, and key performance indicators of data initiatives to senior leadership. **Who You Are** + You have 15+ years of progressive experience in data management, governance, or strategy, with at least 10 years in a senior leadership role building and leading centralized data functions. + You have a deep understanding of the pharmaceutical or life sciences industry, including regulatory requirements like GxP environments and data integrity. + Demonstrated experience driving the implementation of enterprise-wide data strategies that deliver measurable business value, ideally in a manufacturing or technical operations context. + You possess expert-level knowledge of data governance frameworks, architecture principles, master data management, and modern cloud-based data platforms. + You are an exceptional strategic thinker with proven ability to translate complex business challenges into an actionable data strategy and roadmap. Ready for the next step? We look forward to hearing from you. Apply now to discover this exciting opportunity! **Who we are** A healthier future drives us to innovate. Together, more than 100'000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact. Let's build a healthier future, together. **Roche is an Equal Opportunity Employer.**

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. **The Position** **Strategic Alliance Manager - Pharma - Custom Biotech** **Los Angeles / San Diego Region** A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Roche. **The Opportunity:** Building on over 30 years of industry experience, Roche Custom Biotech uses the powerful multidisciplinary skills found in Roche facilities across the world. The team offers products and solutions for manufacturers in the diagnostics and pharma biotech industry ranging from raw materials to system solutions for bioprocessing. Leveraging the unique know-how of Roche Diagnostics and Roche Pharmaceuticals, our Key Account Managers work to deliver high quality raw materials, instrumentation, products and services for the biopharmaceutical, cell therapy, or in vitro diagnostics business. The Strategic Alliance Manager in the pharmaceutical industry is responsible for building, managing, and optimizing relationships with key strategic partners, ensuring that partnerships align with the company's overall business objectives. This role involves collaboration with internal and external stakeholders to drive joint initiatives, maximize value from partnerships, and promote the company's strategic growth in the pharmaceutical market. **The Opportunity:** + Identify, evaluate, and establish strategic alliances with pharmaceutical companies, biotechnology firms, research organizations, and other relevant partners on new and existing opportunities. + Foster strong relationships with existing partners, working closely with your leader, Key Account Executives, ensuring consistent communication, trust, and alignment of goals. Strategic Planning & Execution + Collaborate with internal teams (e.g., business development, regulatory, R&D, marketing) to define partnership objectives and success metrics. + Develop business plans and strategies to maximize the value of partnerships in line with company goals. + Monitor and evaluate alliance results, making data-driven recommendations to improve performance and address challenges. Cross-functional Collaboration + Act as the liaison between the organization and partner companies, ensuring seamless communication and coordination. + Coordinate internal teams to deliver on partnership commitments and milestones, such as co-development projects, joint licensing opportunities, or market entry strategies. + Support regulatory, operational, and logistical efforts linked to partnership agreements. Market Analysis & Opportunity Identification + Conduct competitive intelligence and industry benchmarking to identify partnership opportunities in new and emerging pharmaceutical markets. + Stay updated on trends, technological advancements, and regulatory changes in the industry to identify potential new partnerships or expansion opportunities. Issue Resolution & Risk Management + Address conflicts or challenges in partnerships with a solutions-oriented approach, ensuring smooth progress toward mutual objectives. + Monitor and mitigate risks associated with alliances, including market, legal, and financial risks. Reporting & Performance Monitoring + Prepare and present quarterly reviews and updates to senior management or key stakeholders, highlighting partnership performance and future recommendations. This is a field-based position. The territory is within Los Angeles / San Diego Area and surrounding areas Travel expectation: 25% national travel **Who You Are:** + Bachelor's Degree or equivalent experience + 7+ years relevant sales or equivalent experience **Preferred Requirements** + Proven experience (5+ years) in the pharmaceutical, biotechnology, or healthcare industry, specifically in business development, alliance management, or strategic partnerships. + Strong understanding of pharmaceutical drug development, commercialization processes, and the regulatory landscape. + Experience in negotiating contracts and managing complex partnerships. + Excellent communication, negotiation, and interpersonal skills. + Ability to manage multiple complex projects and initiatives simultaneously. + Strong analytical and problem-solving skills, with the ability to turn data into actionable insights. + Strategic thinker with attention to detail and a results-oriented mindset. + Demonstrated ability to build and maintain strong cross-functional relationships. + Familiarity with global markets and international collaboration processes. Relocation benefits are not available for this job posting. The expected salary range for this position based on the primary location of California is $135,700-$251,900. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position is eligible to earn incentive compensation that is calculated and paid in accordance with the applicable Incentive Compensation Plan for the role. This position also qualifies for the benefits detailed at the link provided below. Benefits (**************************************************** Where pay transparency applies, details are provided based on the primary posting location. For this role, the primary location is Los Angeles. If you are interested in additional locations where the role may be available, we will provide the relevant compensation details later in the hiring process. **Who we are** A healthier future drives us to innovate. Together, more than 100'000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact. Let's build a healthier future, together. Roche is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants (***************************************************************************************************** .

Job Posting: Vertex Fellows ProgramLocation: San Diego, CAFlex Designation: On-Site DesignatedStart Date: August/September 2026Application Deadline: January 9, 2026, by 5:00 PM ETPlease submit a CV/resume and cover letter with your application. Letters of Recommendation will be requested if invited to interview. About the ProgramThe Vertex Fellowship is a unique, one-year training program for outstanding scientists and physicians passionate about solving unmet medical needs and advancing transformative science. Fellows join Vertex for a customized post-doctoral experience, gaining hands-on experience with real-world R&D challenges and benefiting from mentorship by Vertex leaders.This program is designed to provide participants with a broad understanding of the science and business of drug discovery.Program Highlights Project-based Fellowship: Embed for one year within a Vertex project team Work on a project of relevance, based on your skills and our pipeline needs Training & Mentorship Intensive didactic training on the science and business of drug development Scientific mentorship from research leaders Career mentorship from Vertex leaders Exploring Career Fit Upon completion, participants will be able to effectively decide if a career in industry is the right fit, and if so, how they might develop their career Why be a Vertex Fellow? Contribute to transformative medicines: Help patients by advancing scientific ideas in a team-based environment Accelerate your career: Learn about drug discovery and build your professional network Mentorship: Receive guidance from scientific, medical, and business leaders at Verte Vertex Fellows Network: Develop connections internally and externally Program Timeline Applications Accepted: November 24, 2025 - January 9, 2026, by 5:00 PM ET Interview Invitations: February 2026 (Letters of Recommendation requested at this time) Interviews: Early March 2026 Formal Offers: Mid-late March 2026 Program Start: September 2026 Program End: August 2027 Eligibility Requirements PhD, MD, or joint degree attained within 0-5 years Demonstrated scientific impact (e.g., peer-reviewed publications, presentations, awards) Evidence of creative thinking, scientific problem solving, and innovation Interest in learning how scientific research leads to the development of therapies Application InstructionsPlease submit your CV/resume and cover letter by January 9, 2026, 5:00 PM ET.In your cover letter, consider addressing: Your most significant scientific or research achievement and how you accomplished it An example of how you applied creative thinking to solve a problem What you hope to gain from the Vertex Fellows Program Letters of Recommendation will be requested if invited to interview. Pay Range: $110,000 - $165,000 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: On-Site Designated Flex Eligibility Status: In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. #LI-Onsite Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you'll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We're passionate about innovation, inclusion, and supporting your growth-inside and outside the lab. Why Vertex? Real Projects: You'll work on assignments that make a real impact, not just busy work. Mentorship & Networking: Connect with leaders and peers who want to see you succeed through professional networks, connections, and collaborations that will shape your longer-term career. Flexible & Supportive: We offer flexible work options with Flex @ Vertex and prioritize your wellbeing. Inclusive Culture: Collaboration and inclusion are embedded in everything we do. Career Launchpad: Build skills, explore career paths, and get guidance for your future career. Ready to apply? Submit your application and let's turn possibilities into reality! Your Impact The Vertex Discovery Core Applied Technology Group internship program is a multi-week experiential training program. If you are passionate, collaborative, and growth-minded, an internship at Vertex will help you gain meaningful experience in our Discovery Core functional areas and serve as a launchpad for your career. Important Notice Regarding Internship and Co-op Inquiries At Vertex Pharmaceuticals, we are committed to providing a fair and structured recruitment process for all students interested in internship and co-op opportunities. To ensure consistency and equity, all student applications must go through our Early Talent Acquisition Team. Due to the high volume of interest, we are unable to respond to individual solicitation. Direct solicitation to Vertex employees- including senior leaders via email will result in removal from the recruiting process. We appreciate your enthusiasm and interest in Vertex. To be considered for internship or co-op roles, please apply directly through our official application channels. (************************************************************************** Thank you for respecting our process and helping us maintain a fair experience for all candidates. What you will be doing: Vertex Pharmaceuticals is seeking a highly motivated and innovative summer intern to join our Discovery Core Applied Technology (DCAT) Group. The DCAT team designs, develops, and supports cutting-edge automation and software platforms that empower scientists to accelerate drug discovery. As a DCAT intern, you will gain hands-on experience working on a diverse range of technologies, from developing instrument drivers to creating intuitive, user-facing web applications. This role offers a unique opportunity to contribute to impactful projects that directly support Vertex's mission of transforming the lives of people with serious diseases. The successful candidate will: Design and implement instrument drivers to seamlessly integrate new laboratory instruments into our automation platform, ensuring robust performance and scalability. Enhance and troubleshoot existing web applications, adding new features and improving usability. Develop new applications tailored to end-user needs, delivering intuitive and efficient solutions. Evaluate and introduce emerging technologies, testing their applicability within our environment to drive innovation. What you will need to succeed: Software-engineering related background SQL, C#, JavaScript, HTML, CSS Ability to interface and maintain effective relationships with the team Strong written and verbal communication skills Must be available for 10-12 weeks during Summer 2026 (May - August) Must be able to commit to On-site in San Diego, CA UX/UI design skills preferred Python experience preferred Knowledge of configuration management tools (e.g. BitBucket, ect) preferred Legal authorization to work in the United States, now and in the future. Please note that Vertex does not provide sponsorship for internships or entry level roles within this part of the organization. You must be enrolled in an advanced degree program if graduating before August 2026 You must be available to work full-time, 40 hours per week from May - August 2026 Program Details: Full-time, paid internship $20.00 - 32.00 USD/hour Program Dates: May - August 2026 At Vertex, we believe that when you feel your best, you can perform at your best. That's why our US benefits and global well-being resources are designed to support you. • Free 24/7 onsite gym access and free access to group exercise classes • Subsidized commuter benefits- transit and parking • Provided meals-free breakfast daily! • Career development opportunities and events, including C Suite engagement • Social events-both intern-only and company-wide • Location-specific perks and extras! • Recognition of National Intern Day Equal Opportunities Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Vertex is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements. Accessibility & Accommodations We're focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best. Vertex is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com. Export Control Notice This position may involve access to technology or data that is subject to U.S. export control laws, including the Export Administration Regulations (EAR). As such, employment is contingent upon the applicant's ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements, only individuals who qualify as U.S. persons (citizens, permanent residents, asylees, or refugees) are eligible for this position. For this role, Vertex is unable to sponsor non-U.S. persons to apply for an export control license. This job posting is for a temporary role with a third-party agency partner that provides services to Vertex. The individual selected for this role will be offered the role as an employee of that third-party agency; compensation, medical benefits, fringe benefits and other terms and conditions of employment shall be presented by the third-party agency upon offer. For any questions or concerns, please contact early_***************. Pay Range: $0 - $0 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you'll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We're passionate about innovation, inclusion, and supporting your growth-inside and outside the lab. Why Vertex? * Real Projects: You'll work on assignments that make a real impact, not just busy work. * Mentorship & Networking: Connect with leaders and peers who want to see you succeed through professional networks, connections, and collaborations that will shape your longer-term career. * Flexible & Supportive: We offer flexible work options with Flex @ Vertex and prioritize your wellbeing. * Inclusive Culture: Collaboration and inclusion are embedded in everything we do. * Career Launchpad: Build skills, explore career paths, and get guidance for your future career. Ready to apply? Submit your application and let's turn possibilities into reality! Your Impact The Vertex Preclinical Formulation internship program is a multi-week experiential training program for students currently working towards an undergraduate or advanced degree in Pharmacy, Chemistry, Biochemistry, Chemical Engineering, Biochemical Engineering, or a related field of study. If you are passionate, collaborative, and growth-minded, an internship at Vertex will help you gain meaningful experience in our formulation functional areas and serve as a launchpad for your career. Important Notice Regarding Internship and Co-op Inquiries At Vertex Pharmaceuticals, we are committed to providing a fair and structured recruitment process for all students interested in internship and co-op opportunities. To ensure consistency and equity, all student applications must go through our Early Talent Acquisition Team. Due to the high volume of interest, we are unable to respond to individual solicitation. Direct solicitation to Vertex employees- including senior leaders via email will result in removal from the recruiting process. We appreciate your enthusiasm and interest in Vertex. To be considered for internship or co-op roles, please apply directly through our official application channels. (************************************************************************** Thank you for respecting our process and helping us maintain a fair experience for all candidates. What you will be doing: The Preclinical Formulation department located in San Diego, CA is responsible for serving the Chemistry team and preparing Vertex medicines for dosing. To execute this function, we run benchtop experiments to understand how the compounds may translate to animal models. The focus of this position is on automating one of these experiments using a liquid/solid handling robot. We are looking for an enthusiastic intern to learn the robot software, code the workflow, and execute the experiment in simulation/real. The project will conclude with a PowerPoint and/or poster presentation to the site on findings. Key responsibilities include: * Learning the day-to-day experiments of preclinical formulation experimentation * Running benchtop experiments using a wide variety of wet lab instruments including but not limited to pipettes, centrifuges, pH meters and analytical equipment * Learning liquid/solid handling software and hardware * Designing/coding liquid handling workflow What you will need to succeed: * Enrolled in an undergraduate (Junior or Senior preferred but will consider underclass applicants with extensive experience) or graduate degree program and majoring in Pharmacy, Chemistry, Biochemistry, Chemical Engineering, Biochemical Engineering, Biomedical Engineering, or a related scientific field. * Wet lab experience (pipetting, pH meter use, proper lab safety) * Basic coding knowledge (logic, loops, variable understanding and function understanding) * Excellent communication and presentation skills * Legal authorization to work in the United States, now and in the future. Please note that Vertex does not provide sponsorship for internships or entry level roles within this part of the organization. * You must be available to work full-time, 40 hours per week from May - August 2026 Program Details: * Full-time, paid internship $20.00 - 32.00 USD/hour * Program Dates: May - August 2026 At Vertex, we believe that when you feel your best, you can perform at your best. That's why our US benefits and global well-being resources are designed to support you. * Free 24/7 onsite gym access and free access to group exercise classes * Subsidized commuter benefits- transit and parking * Provided meals-free breakfast daily! * Career development opportunities and events, including C Suite engagement * Social events-both intern-only and company-wide * Location-specific perks and extras! * Recognition of National Intern Day Equal Opportunities Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Vertex is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements. Accessibility & Accommodations We're focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best. Vertex is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com. Export Control Notice This position may involve access to technology or data that is subject to U.S. export control laws, including the Export Administration Regulations (EAR). As such, employment is contingent upon the applicant's ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements, only individuals who qualify as U.S. persons (citizens, permanent residents, asylees, or refugees) are eligible for this position. For this role, Vertex is unable to sponsor non-U.S. persons to apply for an export control license. This job posting is for a temporary role with a third-party agency partner that provides services to Vertex. The individual selected for this role will be offered the role as an employee of that third-party agency; compensation, medical benefits, fringe benefits and other terms and conditions of employment shall be presented by the third-party agency upon offer. For any questions or concerns, please contact early_*************** Pay Range: $0 - $0 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. The Position National Business Manager - Custom Biotech A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Roche. The Opportunity As the National Business Manager - Custom Biotech, you will guide and inspire a team of driven Sales Specialists and build a high-performing, engaged sales organization that partners closely with R&D leaders across biopharma and diagnostics organizations. You'll shape and execute the national sales strategy for Roche's high-quality raw materials portfolio, develop strong customer partnerships from early research through commercialization, and lead with a people-first mindset. If you're a leader who is passionate about building and developing talent, driving performance, and enabling scientific innovation that improves healthcare outcomes-this is your opportunity to lead with purpose and vision. As the National Business Manager, you will: manage a staff of sales specialists and participates in the establishment of sales and financial goals for a given region, designing and ensuring implementation of sales plans to achieve these goals. interact with sales leadership to communicate sales performance in territory, and partner with Marketing to implement promotional strategies and to monitor competitor activities. assist the Director or senior leadership in overall operations of assigned department(s). contribute and achieve results through the management of subordinates (professional and support staff). establish and manage the department budget and all assigned resources. Provide leadership to ensure department objectives and goals are achieved. direct and implement tactical plans. Has full discretion on all employment decisions for the department staff including hiring, training, performance management, and progressive disciplinary actions. be responsible for maintaining and continuously improving the quality system and achieving quality objectives through daily actions. This is a field-based position. The territory is within California, Nevada, Oregon, Washington, Idaho, Montana & Wyoming. Ideal candidate to live in San Diego or Los Angeles. Travel expectation: 25% national travel Who You Are Bachelor's Degree 3+ year's relevant sales or equivalent experience with demonstrated success 1-2 years management or equivalent leadership experience with demonstrated strong competency and proven track record in sales management and leadership Preferred Qualifications 5 - 10 years' management or equivalent leadership experience with demonstrated strong competency and proven track record in sales management and leadership Excellent oral and written communication skills including making impactful presentations Negotiation, contracting and problem solving skills Ability to work within a regulated environment Strategic planning and organizational skills High levels of sales proficiency and/or industry specific experience Relocation benefits are not available for this job posting The expected salary range for this position based on the primary location of California is $142,200-$264,000. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position is eligible to earn incentive compensation that is calculated and paid in accordance with the applicable Incentive Compensation Plan for the role. This position also qualifies for the benefits detailed at the link provided below. Benefits Where pay transparency applies, details are provided based on the primary posting location. For this role, the primary location is San Diego. If you are interested in additional locations where the role may be available, we will provide the relevant compensation details later in the hiring process.Who we are A healthier future drives us to innovate. Together, more than 100'000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact. Let's build a healthier future, together. Roche is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. The Position 2026 Summer Intern - Maintenance & Reliability Engineering Department Summary The Maintenance & Reliability Engineering team is responsible for ensuring equipment uptime, operational readiness, and effective spare-parts management to support 24-hour manufacturing and laboratory operations at GenMark Diagnostics. The team partners closely with Manufacturing, Engineering, and Supply Chain to execute preventive maintenance activities while designing, implementing, and sustaining a Kanban-based spare parts management system. A key focus of the organization is the development and continuous improvement of standardized maintenance processes, visual inventory controls, and data-driven spare parts strategies to reduce downtime, eliminate material shortages, and improve maintenance response time. These efforts directly support reliable production and laboratory operations for the ePlex molecular diagnostic instruments, enabling timely delivery of products that support patient care. This internship position is located in CARLSBAD, CA, on site. The Opportunity Ownership of an impactful project that improves performance using principles of Lean Six Sigma to reduce process variation and driving work standardization and flow. Final presentation near the conclusion of internship to senior leaders. Program Highlights Intensive 12-weeks, full time (40 hours per week) paid internship. Program start dates are in May/June (Summer). A stipend, based on location, will be provided to help alleviate costs associated with the internship. Ownership of challenging and impactful business-critical projects. Work with some of the most talented people in the biotechnology industry. Who You Are Required Education Must be pursuing a Bachelor's Degree (enrolled student). Must have attained a Bachelor's Degree (not currently enrolled in a graduate program). Must be pursuing a Master's Degree (enrolled student). Required Majors Mechanical Engineering, Electrical Engineering, Electronic Engineering, Chemical Engineering, Physics or related fields. Required Skills Good Documentation Practices. Safety & Compliance. Engineering Fundamentals. Data Collection. Documentation Support. Attendance & Reliability. Communication.. Preferred Qualifications Demonstrated proficiency in the application of basic engineering and/or scientific theories, principles and techniques. Possess strong analytical skills plus technical and mechanical aptitude. Proficiency with Google Suite. Excellent communication and interpersonal skills. Ability to work both independently and collaboratively. Complements our culture and the standards that guide our daily behavior & decisions: Integrity, Courage, and Passion. Efficient, organized, and able to handle short timelines in a fast-paced environment. Complete work in a timely, accurate and thorough manner. Relocation benefits are not available for this job posting. The expected salary range for this position based on the primary location of California is $45.00 - $50.00/hour. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for paid holiday time off benefits. Who we are GenMark is now a proud member of the Roche Group, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. As a global leader in healthcare, Roche Diagnostics offers a broad portfolio of products, tools and services that help in the prevention, diagnosis and management of diseases like HPV, HIV, hepatitis and diabetes as well as other medical conditions, such as fertility and blood coagulation. With the addition of GenMark to the Roche Group, syndromic infectious disease diagnostics is now added to the long list of disease states and conditions that the Roche Group addresses. GenMark's ePlex true sample-to-answer system offers unique solutions to address the most significant challenges facing clinical laboratories, while supporting hospital systems to deliver patient-centered, value-based care. ePlex streamlines the diagnostic workflow from physician order entry to the final test report and is the true sample-to-answer solution designed to improve patient care, reduce costs, and increase lab efficiency. GenMark is headquartered in Carlsbad, California. GenMark is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has approved medicines that treat the underlying causes of multiple chronic, life-shortening genetic diseases - cystic fibrosis, pain, sickle cell disease and transfusion-dependent beta thalassemia - and continues to advance clinical and research programs in these diseases. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases. The Principal Research Scientist will focus on targeted drug delivery including nucleic acid therapies. This role will be on-site in our state-of-the-art research site in San Diego. The successful candidate will have extensive expertise in receptor biology and targeted delivery in extrahepatic tissues/cells which is instrumental in the development of novel therapeutics. Key Duties and Responsibilities: Develop and implement strategic plans for receptor & ligand identification, characterization, optimization, and application in drug discovery. Responsible for executing research plans, collecting and interpreting data, trouble shooting, and defining next steps. Collaborate with cross-functional partners (medicinal chemistry, computational genomics, molecular and cellular biology, pharmacology, protein sciences) to support integrated drug discovery programs from target validation through lead optimization. Apply innovative approaches and stay current with advances in receptor biology, ligand discovery, and nucleic acid therapeutics to strengthen pipeline opportunities. Prepare and present data in project team meetings, contributing scientific insight and recommendations to guide program strategy. Maintain high standards of scientific rigor, accurate documentation, data integrity, and compliance with regulatory guidelines. Knowledge and Skills: Strong expertise in receptor biology, ligand-receptor interactions and signaling mechanisms. Hands-on experience with biochemical, biophysical, and/or cell-based assays to study receptor function and behavior. Experience with ligand-mediated delivery into specific tissues or cell types is highly desirable. Demonstrated track record of scientific achievement (e.g., publications, presentations, or contributions to therapeutic programs) in receptor biology and targeted drug delivery. Ability to collaborate effectively within multidisciplinary project teams. Excellent personal and communication skills, with the ability to influence stakeholders and drive decision-making across functions. Proven ability to thrive in a fast-paced, multidisciplinary, and innovative environment Education and Experience: Ph.D. (or equivalent degree) in biology, biochemistry or related science and 4-7 years of relevant post-doctoral employment experience, or Master's degree (or equivalent degree) in biology, biochemistry or related science and 7+ years of relevant employment experience, or Bachelor's Degree (or equivalent degree) in biology, biochemistry or related science and 10+ years of relevant employment experience #LI-KM1 #LI-Onsite Pay Range: $136,000 - $204,000 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: On-Site Designated Flex Eligibility Status: In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Vertex is a global biotechnology company that invests in scientific innovation. The Data, Technology and Engineering (DTE) Research, Pre-Clinical, Manufacturing & Supply (RPMS) Group's mission is to improve the lives of patients through digital, data, and technology innovation. Vertex is in a transformational period where we are accelerating our capabilities, technology and data to augment our scientific mission and enable Vertex to grow in scale; ensuring we remain on the forefront of science, medicine and technology. Role Overview We are seeking a data driven, scientifically literate, and technically skilled Principal Engineer to serve as the Automated Data QC and Reporting Solutions lead to automate and streamline pre-clinical data pipelines and reporting processes and ensure the accuracy, consistency, and integrity of high impact, high visibility, and business-critical regulatory documents across research laboratories.We are seeking a data driven, scientifically literate, and technically skilled Principal Engineer to serve as the Automated Data QC and Reporting Solutions lead to automate and streamline pre-clinical data pipelines and reporting processes and ensure the accuracy, consistency, and integrity of high impact, high visibility, and business-critical regulatory documents across research laboratories. This role will drive the modernization and standardization of data pipelines and reporting processes, ensuring accuracy, consistency, and integrity of high-impact, business-critical regulatory documents across research laboratories. The Principal Engineer will also develop and execute strategies for data consumption solutions and reporting, leveraging advanced technology, agentic workflows, and AI capabilities to modernize and scale data consumption environments. Key Duties and Responsibilities Develop and execute modernization and standardization initiatives for automated QC and reporting of research data, ensuring alignment with business objectives and digital transformation goals. Lead the development of data consumption solution strategies and reporting frameworks to enable scalable, future-ready, and unified data environments. Identify and implement innovative digital and AI-powered technologies, including agentic workflows, to enhance data consumption, reporting, and scientific insight generation. Collaborate with cross-functional teams to align global digital QC, reporting, and data consumption strategies across multiple research sites. Operational Execution Design, configure, develop, and maintain automated solutions, tools, and workflows for QC, report generation, and standardized data consumption. Regularly evaluate and optimize solutions, scripts, and workflows to enhance performance, scalability, and interoperability. Identify and prepare raw data files in response to regulatory requests. Deliver solutions to automate and digitalize by identifying and preparing raw data files in response to regulatory requests. Design, configure, develop and maintain automated solutions, tools and workflows for automated QC and report generation. Ensure the accuracy, completeness, traceability and consistency of data across research business-critical documents (e.g. research study reports). Ensure generated reports meet formatting, regulatory, data integrity, and quality standards. Identify and resolve data discrepancies using automated processes, collaborating with stakeholders. Collaborate across our Data Technology & Engineering (DTE) organization and with research scientists to ensure solutions integrate with our broader data platform and data engineering strategy. Ensure the accuracy, security, quality and business continuity of solutions in line with Vertex and external data and technology standards. Modernization and AI Enablement Drive the adoption of agentic workflows and AI capabilities to automate and accelerate scientific data workflows, reporting, and consumption interfaces Develop and deploy AI-enhanced visualization, reporting, and QC interpretation tools. Champion the use of cloud-native and unified semantic consumption layers for scalable data access and analysis. Collaboration and Communication Partner with scientists, statisticians, and program representatives to understand reporting and QC requirements. Partner with DTE leaders to understand and deliver to data and technical requirements. Provide leadership and training to a team of super users on automated QC and report generation workflows to ensure business continuity. Develop a sustainable suite of solutions that minimize future training. Deliver solutions and insights with clear and actionable QC and reporting summaries to stakeholders. Required Knowledge and Skills Experience designing and implementing data and technology solutions in life sciences research and development. Advanced programming skills in R, Python, and experience with database access, query, and large dataset interrogation. Expertise in agentic workflows, AI/ML technologies, and cloud-native platforms for data engineering and reporting. Proficiency in evaluating and implementing new tools and technologies, including AI and agentic workflows. Proficiency in data management and automation principles and methodologies. Knowledge of statistics, data visualization, and scientific reporting. Familiarity with data quality, reporting, and compliance requirements in regulated environments. Excellent collaboration, interpersonal, and communication skills, with the ability to present complex technical concepts to diverse audiences. Strong analytical, problem-solving, and decision-making skills using data-driven approaches. Strong collaboration and inter-personal skills. Proven track record of working in a complex, fast-paced environment. Willingness to travel as needed (up to 10%) to support business objectives. Required Education and Experience Bachelor's degree in a relevant field such as Computer Science, Data Science, Engineering, or a related discipline or equivalent experience; advanced degree preferred. 5+ years of experience in technical leadership, data management, or related roles within the biotechnology or pharmaceutical industry. Proven track record of leveraging data engineering, software engineering and or data science skills to automate reporting. Proficiency in digital platforms and technologies, with the ability to evaluate and implement new tools and technologies. Proven track record in leading digital transformation, modernization, and standardization initiatives. #LI - Hybrid Pay Range: $148,000 - $222,000 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

The Senior Director, Structural Biology and Biophysics will define and execute a forward-looking vision for structural biology and biophysics to accelerate drug discovery. This leader will further develop our research capabilities in structure-enabled discovery, driving scientific excellence, innovation, and integration across disciplines. Based at our state-of-the-art research site in San Diego, this individual will combine deep technical expertise with strategic foresight to position structural biology as a core differentiator in our discovery platform. KEY RESPONSIBILITIES Define and articulate a scientific vision and strategic plans that integrate experimental structural biology and biophysics data as well as computational approaches to accelerate drug discovery Lead and manage a team specialized in structural biology and biophysics. Provide guidance and mentorship. Foster a collaborative work environment. Champion existing and new structural biology and biophysical technologies that advance drug discovery projects forward. Propose new applications, apply technology, and follow up on new MoA, drug target and binding site identification and/or kinetic analysis of drug binding. Synthesize diverse approaches across modalities, build strategic collaborations within and outside the organization, and articulate how structural insights translate to biological and therapeutic impact. Independently perform hands-on experimental troubleshooting and methods development in biophysical assay development and protein structure determination by crystallography and/or CryoEM. Stay current with the latest advancements in the field of structural biology and biophysics, and integrate new technologies and methodologies into the drug discovery process. Propose and implement novel and improved data analysis tools. Maintain the excellence of standards for structure and interpretation of all laboratory records, electronic database entries, internal reports, patents, and external communications from the team. Ensure compliance with relevant regulatory guidelines, maintain accurate records, and promote a culture of scientific rigor and integrity within the team. Ensure effective interaction & communication between the structural biology and biophysics group and other disciplines within Research such as pharmacology, molecular and cellular biology, computational chemistry, etc. Develop and implement strategies in collaboration with key stakeholders to ensure the discovery and development of clinical candidates with high clinical success rates. Lead and/or contribute to cross-site and cross-functional goals within Vertex. Required Education Level Ph.D. (or equivalent degree) in Structural Biology, Biophysics, or a related field and 11+ years of industry / academic experience with a minimum of 5 years managing a team. Master's degree (or equivalent degree) and 15+ years of relevant employment experience, or Bachelor's Degree (or equivalent degree) and 20+ years of relevant employment experience. Extensive experience in pharmaceutical, biotechnology, or leading academic biomedical research setting, with a proven track record of leading and managing teams in structural biology and biophysics. Experience in applying structural biology and biophysics to advance drug discovery programs. Required Knowledge/Skills Established reputation with a strong track record of scientific impact in driving drug discovery programs forward by initiating and implementing structural biology and biophysics for mechanism-of-action studies and drug target or protein binding site identification and characterization. Experience can come from functional or cross-functional project leadership roles. Industry experience is preferred. Demonstrated ability to craft and communicate a unifying scientific vision that integrates structural biology, biophysics, and computation into discovery strategies. Proven success in applying structural insights to advance drug discovery from target validation through lead optimization. Experience with integral membrane proteins is highly desirable. Experience in managing scientific teams, individual and team performance, goal setting, and career growth development and building a culture of innovation and inclusion. Demonstrated independent thought/creativity in science, leadership skills, and ability to inspire and motivate drug discovery teams. Excellent communication (oral and written) in articulating goals, objectives and results to the group and larger cross-functional project teams. Strong inter-personal, oral, and written communication skills. Extensive experience interfacing with internal and external stakeholders to collaborate and execute on research programs, deliver results, and influence decision making. Ability to navigate and be successful in a fast-paced, innovative, and multi-disciplinary work environment. #LI-KM1 #LI-Onsite Pay Range: $221,900 - $332,800 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: On-Site Designated Flex Eligibility Status: In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. **The Position** **Digital Enterprise Executive** The Digital Enterprise Executive plays a lead role in the development and execution of digital sales strategies, ensuring Roche is well-positioned for strong customer partnerships and experiences. This role requires a strategic approach to customer relationship management, with a focus on C-Suite executives, to expand Roche's market share and business portfolio. The position requires an in-depth understanding of regional and national market dynamics, industry trends, and Roche's comprehensive product portfolio to deliver superior value-based solutions. **Key Responsibilities:** + Establish and maintain strong relationships with executive-level IHN assigned customers to drive growth, profitability, and predictability. + Lead the development, composition, and execution of digital sales strategies to achieve sales objectives. + Utilize strong product knowledge, industry insights, and software sales expertise to align customer goals with Roche digital solutions. + Continuously analyze industry trends, competitive intelligence, and market data to drive actionable insights for Roche colleagues. + Collaborate cross-functionally to manage the strategic vision and ensure alignment with customer needs. + Drive the co-creation of strategic roadmaps with customers based on their near and long-term goals. + Identify potential risks in customer environments, working proactively with internal stakeholders to mitigate challenges. + Develop programs and campaigns to enhance Roche's positioning and brand recognition within the US market by successfully developing partnerships with assigned accounts. + Build competitive immunity by fostering strong, value-driven relationships with key decision-makers, including C-Suite executives, Board Members, CMOs, and CIOs. + Ensure Roche is positioned as a leader in workflow optimization, decision support, and value-based healthcare initiatives. + Coordinate multidisciplinary teams with end-to-end accountabilities for delivering complete product and service solutions. **Who you are:** + Bachelor's degree or equivalent experience + 7+ years relevant sales or equivalent experience + Expertise in managing complex sales cycles and long-term strategic partnerships. + Exceptional communication, negotiation, and relationship management skills. + Ability to navigate a heavily matrixed organization and lead cross-functional teams effectively. **Preferred Qualifications:** + Bachelor's degree in Business, Healthcare, or related field + MBA preferred + Proven track record in digital solutions sales into the healthcare industry or healthcare technology sales + Experience in navigating and selling into Integrated Health Systems and/or Integrated Delivery Systems. + Strong knowledge of national healthcare market dynamics. + Deep understanding of cloud-based software, digital health solutions, and healthcare informatics. + Strong analytical mindset with the ability to translate data into actionable strategies. + High adaptability to changing market conditions and customer needs. **Additional Information** **This is a field based role - Travel in this role estimated 50%+.** **Multiple positions available** _The expected salary range for this position based on the primary location of Indianapolis, IN is $129,200-240,000. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position is eligible to earn incentive compensation that is calculated and paid in accordance with the applicable Incentive Compensation Plan for the role. This position also qualifies for the benefits detailed at the link provided below._ *************************************************** _Relocations benefits are not available for this position_ **Who we are** A healthier future drives us to innovate. Together, more than 100'000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact. Let's build a healthier future, together. Roche is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants (***************************************************************************************************** .

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you'll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We're passionate about innovation, inclusion, and supporting your growth-inside and outside the lab. Why Vertex? Real Projects: You'll work on assignments that make a real impact, not just busy work. Mentorship & Networking: Connect with leaders and peers who want to see you succeed through professional networks, connections, and collaborations that will shape your longer-term career. Flexible & Supportive: We offer flexible work options with Flex @ Vertex and prioritize your wellbeing. Inclusive Culture: Collaboration and inclusion are embedded in everything we do. Career Launchpad: Build skills, explore career paths, and get guidance for your future career. Ready to apply? Submit your application and let's turn possibilities into reality! Your Impact The Vertex Preclinical Formulation internship program is a multi-week experiential training program for students currently working towards an undergraduate or advanced degree in Pharmacy, Chemistry, Biochemistry, Chemical Engineering, Biochemical Engineering, or a related field of study. If you are passionate, collaborative, and growth-minded, an internship at Vertex will help you gain meaningful experience in our formulation functional areas and serve as a launchpad for your career. Important Notice Regarding Internship and Co-op Inquiries At Vertex Pharmaceuticals, we are committed to providing a fair and structured recruitment process for all students interested in internship and co-op opportunities. To ensure consistency and equity, all student applications must go through our Early Talent Acquisition Team. Due to the high volume of interest, we are unable to respond to individual solicitation. Direct solicitation to Vertex employees- including senior leaders via email will result in removal from the recruiting process. We appreciate your enthusiasm and interest in Vertex. To be considered for internship or co-op roles, please apply directly through our official application channels. (************************************************************************** Thank you for respecting our process and helping us maintain a fair experience for all candidates. What you will be doing: The Preclinical Formulation department located in San Diego, CA is responsible for serving the Chemistry team and preparing Vertex medicines for dosing. To execute this function, we run benchtop experiments to understand how the compounds may translate to animal models. The focus of this position is on automating one of these experiments using a liquid/solid handling robot. We are looking for an enthusiastic intern to learn the robot software, code the workflow, and execute the experiment in simulation/real. The project will conclude with a PowerPoint and/or poster presentation to the site on findings. Key responsibilities include: Learning the day-to-day experiments of preclinical formulation experimentation Running benchtop experiments using a wide variety of wet lab instruments including but not limited to pipettes, centrifuges, pH meters and analytical equipment Learning liquid/solid handling software and hardware Designing/coding liquid handling workflow What you will need to succeed: Enrolled in an undergraduate (Junior or Senior preferred but will consider underclass applicants with extensive experience) or graduate degree program and majoring in Pharmacy, Chemistry, Biochemistry, Chemical Engineering, Biochemical Engineering, Biomedical Engineering, or a related scientific field. Wet lab experience (pipetting, pH meter use, proper lab safety) Basic coding knowledge (logic, loops, variable understanding and function understanding) Excellent communication and presentation skills Legal authorization to work in the United States, now and in the future. Please note that Vertex does not provide sponsorship for internships or entry level roles within this part of the organization. You must be available to work full-time, 40 hours per week from May - August 2026 Program Details: Full-time, paid internship $20.00 - 32.00 USD/hour Program Dates: May - August 2026 At Vertex, we believe that when you feel your best, you can perform at your best. That's why our US benefits and global well-being resources are designed to support you. • Free 24/7 onsite gym access and free access to group exercise classes • Subsidized commuter benefits- transit and parking • Provided meals-free breakfast daily! • Career development opportunities and events, including C Suite engagement • Social events-both intern-only and company-wide • Location-specific perks and extras! • Recognition of National Intern Day Equal Opportunities Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Vertex is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements. Accessibility & Accommodations We're focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best. Vertex is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com. Export Control Notice This position may involve access to technology or data that is subject to U.S. export control laws, including the Export Administration Regulations (EAR). As such, employment is contingent upon the applicant's ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements, only individuals who qualify as U.S. persons (citizens, permanent residents, asylees, or refugees) are eligible for this position. For this role, Vertex is unable to sponsor non-U.S. persons to apply for an export control license. This job posting is for a temporary role with a third-party agency partner that provides services to Vertex. The individual selected for this role will be offered the role as an employee of that third-party agency; compensation, medical benefits, fringe benefits and other terms and conditions of employment shall be presented by the third-party agency upon offer. For any questions or concerns, please contact early_*************** Pay Range: $0 - $0 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. The Position As a Maintenance Calibration/Metrology Technician joining our Carlsbad team, you will play a crucial role in leading and supervising a team of calibration technicians. You are ensuring the calibration accuracy and reliability of GenMark's equipment. The Opportunity Ensure timely completion of calibration activities. Assigning, overseeing, and performing the calibration of a wide range of instruments and equipment. Ensuring all calibration activities comply with company policies and regulatory standards. Developing and maintaining calibration procedures and documentation. Reviewing and approving calibration certificates and records. Investigating and resolving discrepancies or non-conformances Providing training and guidance to calibration technicians. Assist with on-the-job training of lower-level technicians. Demonstrate awareness of applicable safety guidelines and standards. Assisting in monitoring and troubleshooting the Temperature Monitoring System and providing technical support for equipment non-conformances. Equipment validations (IQ/OQ) and documenting all activities following Good Documentation Practice. Maintaining the Kanban system by updating inventory levels, monitoring card movements, and replenishing stock as needed. Conduct regular audits, identify discrepancies, and implement corrective actions. Supporting the Manufacturing Engineering group with continuous process improvement projects. Lead special projects as requested and perform additional duties as assigned. Who you are You bring a High School Diploma or Equivalent; Associate degree or technical/trade school in Engineering or Scientific field preferred 6-8 years of experience in a regulated manufacturing environment is required. Asset Database Management system, FDA, cGMPs, and/or ISO, CFR-Part 820 knowledge and experience is required Behaviors, competencies, and qualities of the ideal applicant. Strong quality orientation with attention to detail and a desire to deliver service excellence is highly desired. Experience using documents and quality control procedures which include best practices Demonstrated ability to analyze and solve equipment faults issues in both mechanical and electronic systems and provide a root cause. Strong problem-solving, judgment, and decision-making skills. Able to use computer software programs such as Word, and Excel Experience with automated liquid reagent dispensing systems (Biodot, etc..); with surface modification (plasma, Corona, etc..) and spray coating; with machine vision system (Cognex, Keyence, etc.) is a plus Relocation benefits are not offered for this job posting. The expected salary range for this position, based on the primary location of California is 49,300.00 - 91,500.00 USD Annual. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below. Benefits. Who we are GenMark is now a proud member of the Roche Group, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. As a global leader in healthcare, Roche Diagnostics offers a broad portfolio of products, tools and services that help in the prevention, diagnosis and management of diseases like HPV, HIV, hepatitis and diabetes as well as other medical conditions, such as fertility and blood coagulation. With the addition of GenMark to the Roche Group, syndromic infectious disease diagnostics is now added to the long list of disease states and conditions that the Roche Group addresses. GenMark's ePlex true sample-to-answer system offers unique solutions to address the most significant challenges facing clinical laboratories, while supporting hospital systems to deliver patient-centered, value-based care. ePlex streamlines the diagnostic workflow from physician order entry to the final test report and is the true sample-to-answer solution designed to improve patient care, reduce costs, and increase lab efficiency. GenMark is headquartered in Carlsbad, California. GenMark is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. The Position National Business Manager - Custom Biotech A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Roche. The Opportunity As the National Business Manager - Custom Biotech, you will guide and inspire a team of driven Sales Specialists and build a high-performing, engaged sales organization that partners closely with R&D leaders across biopharma and diagnostics organizations. You'll shape and execute the national sales strategy for Roche's high-quality raw materials portfolio, develop strong customer partnerships from early research through commercialization, and lead with a people-first mindset. If you're a leader who is passionate about building and developing talent, driving performance, and enabling scientific innovation that improves healthcare outcomes-this is your opportunity to lead with purpose and vision. As the National Business Manager, you will: * manage a staff of sales specialists and participates in the establishment of sales and financial goals for a given region, designing and ensuring implementation of sales plans to achieve these goals. * interact with sales leadership to communicate sales performance in territory, and partner with Marketing to implement promotional strategies and to monitor competitor activities. * assist the Director or senior leadership in overall operations of assigned department(s). * contribute and achieve results through the management of subordinates (professional and support staff). * establish and manage the department budget and all assigned resources. Provide leadership to ensure department objectives and goals are achieved. * direct and implement tactical plans. Has full discretion on all employment decisions for the department staff including hiring, training, performance management, and progressive disciplinary actions. * be responsible for maintaining and continuously improving the quality system and achieving quality objectives through daily actions. This is a field-based position. The territory is within California, Nevada, Oregon, Washington, Idaho, Montana & Wyoming. Ideal candidate to live in San Diego or Los Angeles. Travel expectation: 25% national travel Who You Are * Bachelor's Degree * 3+ year's relevant sales or equivalent experience with demonstrated success * 1-2 years management or equivalent leadership experience with demonstrated strong competency and proven track record in sales management and leadership Preferred Qualifications * 5 - 10 years' management or equivalent leadership experience with demonstrated strong competency and proven track record in sales management and leadership * Excellent oral and written communication skills including making impactful presentations Negotiation, contracting and problem solving skills * Ability to work within a regulated environment * Strategic planning and organizational skills * High levels of sales proficiency and/or industry specific experience Relocation benefits are not available for this job posting The expected salary range for this position based on the primary location of California is $142,200-$264,000. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position is eligible to earn incentive compensation that is calculated and paid in accordance with the applicable Incentive Compensation Plan for the role. This position also qualifies for the benefits detailed at the link provided below. Benefits Where pay transparency applies, details are provided based on the primary posting location. For this role, the primary location is San Diego. If you are interested in additional locations where the role may be available, we will provide the relevant compensation details later in the hiring process. Who we are A healthier future drives us to innovate. Together, more than 100'000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact. Let's build a healthier future, together. Roche is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. **The Position** **2026 Summer Intern - Maintenance & Reliability Engineering** **Department Summary** The Maintenance & Reliability Engineering team is responsible for ensuring equipment uptime, operational readiness, and effective spare-parts management to support 24-hour manufacturing and laboratory operations at GenMark Diagnostics. The team partners closely with Manufacturing, Engineering, and Supply Chain to execute preventive maintenance activities while designing, implementing, and sustaining a Kanban-based spare parts management system. A key focus of the organization is the development and continuous improvement of standardized maintenance processes, visual inventory controls, and data-driven spare parts strategies to reduce downtime, eliminate material shortages, and improve maintenance response time. These efforts directly support reliable production and laboratory operations for the ePlex molecular diagnostic instruments, enabling timely delivery of products that support patient care. This internship position is located in **CARLSBAD, CA, on site.** **The Opportunity** + Ownership of an impactful project that improves performance using principles of Lean Six Sigma to reduce process variation and driving work standardization and flow. + Final presentation near the conclusion of internship to senior leaders. **Program Highlights** + Intensive 12-weeks, full time (40 hours per week) paid internship. + Program start dates are in May/June (Summer). + A stipend, based on location, will be provided to help alleviate costs associated with the internship. + Ownership of challenging and impactful business-critical projects. + Work with some of the most talented people in the biotechnology industry. **Who You Are** **Required Education** + Must be pursuing a Bachelor's Degree (enrolled student). + Must have attained a Bachelor's Degree (not currently enrolled in a graduate program). + Must be pursuing a Master's Degree (enrolled student). **Required Majors** + Mechanical Engineering, Electrical Engineering, Electronic Engineering, Chemical Engineering, Physics or related fields. **Required Skills** + Good Documentation Practices. + Safety & Compliance. + Engineering Fundamentals. + Data Collection. + Documentation Support. + Attendance & Reliability. + Communication.. **Preferred Qualifications** + Demonstrated proficiency in the application of basic engineering and/or scientific theories, principles and techniques. + Possess strong analytical skills plus technical and mechanical aptitude. + Proficiency with Google Suite. + Excellent communication and interpersonal skills. + Ability to work both independently and collaboratively. + Complements our culture and the standards that guide our daily behavior & decisions: Integrity, Courage, and Passion. + Efficient, organized, and able to handle short timelines in a fast-paced environment. + Complete work in a timely, accurate and thorough manner. **Relocation benefits are not available for this job posting.** The expected salary range for this position based on the primary location of California is $45.00 - $50.00/hour. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for paid holiday time off benefits. **Who we are** GenMark is now a proud member of the Roche Group, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. As a global leader in healthcare, Roche Diagnostics offers a broad portfolio of products, tools and services that help in the prevention, diagnosis and management of diseases like HPV, HIV, hepatitis and diabetes as well as other medical conditions, such as fertility and blood coagulation. With the addition of GenMark to the Roche Group, syndromic infectious disease diagnostics is now added to the long list of disease states and conditions that the Roche Group addresses. GenMark's ePlex true sample-to-answer system offers unique solutions to address the most significant challenges facing clinical laboratories, while supporting hospital systems to deliver patient-centered, value-based care. ePlex streamlines the diagnostic workflow from physician order entry to the final test report and is the true sample-to-answer solution designed to improve patient care, reduce costs, and increase lab efficiency. GenMark is headquartered in Carlsbad, California. GenMark is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants (***************************************************************************************************** .

Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has approved medicines that treat the underlying causes of multiple chronic, life-shortening genetic diseases - cystic fibrosis, pain, sickle cell disease and transfusion-dependent beta thalassemia - and continues to advance clinical and research programs in these diseases. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases. The Senior Director of Nucleic Acid Therapy will drive research to advance the delivery of nucleic acid-based therapeutics. The ideal candidate brings deep expertise in ligand-mediated extrahepatic delivery and nucleic acid chemistry, coupled with the vision to anticipate project needs and the judgment to know when to refine current strategies or pursue new directions. Candidates with background in si RNA/ASO's and experience with multiple ligand platforms (antibody, peptide, small molecules, etc) will be prioritized. Key Duties and Responsibilities: Lead and manage a team of cross-functional scientists, provide guidance and mentorship, foster a collaborative work environment. Develop and implement strategic plans to leverage various approaches for receptor and ligand identification, chemistry optimization, and implementation in drug discovery. Work with team to execute research plans, collecting and interpreting data, trouble shooting, and defining next steps. Collaborate with cross-functional teams, including medicinal chemists, computational scientists, molecular and cellular biologists, and pharmacologists to drive integrated drug discovery projects from target selection to lead optimization and delivery of clinical candidates. Stay current with the latest advancements in the field of nucleic acid chemistry and delivery, and integrate new technologies and methodologies into the drug discovery process. Ensure compliance with relevant regulatory guidelines, maintain accurate records, and promote a culture of scientific rigor and integrity within the team. Knowledge and Skills: Established reputation with a strong track record of scientific impact in driving nucleic acid drug discovery programs forward by applying chemistry and delivery optimization. Industry experience is preferred. Extensive experience with nucleic acid drug discovery is highly desirable. Experience in managing scientific teams, individual and team performance, goal setting, career growth development, and building a culture of innovation and inclusion. Demonstrated innovation in science, leadership skills, and ability to inspire and motivate drug discovery teams. Strong inter-personal, oral, and written communication skills. Extensive experience interfacing with internal and external stakeholders to collaborate and execute on research programs, deliver results, and influence decision making. Ability to navigate and be successful in a fast-paced, innovative, and multi-disciplinary work environment. Education and Experience: Ph.D. (or equivalent degree) in chemistry, biochemistry, or a related field and 11+ years of industry / academic experience with a minimum of 5 years managing a team. Master's degree (or equivalent degree) and 15+ years of relevant employment experience, or Bachelor's Degree (or equivalent degree) and 20+ years of relevant employment experience. Extensive experience in pharmaceutical, biotechnology, or leading academic biomedical research setting, with a proven track record of scientific accomplishments and deliverables. #LI-KM1 #LI-Onsite Pay Range: $217,000 - $325,500 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: On-Site Designated Flex Eligibility Status: In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com