Postdoctoral Fellow, Early Discovery Biochemistry / Peptide Therapeutics, Fairbrother Lab
The Position
A postdoctoral fellow position is available in the Early Discovery Biochemistry / Peptide Therapeutics Department at Genentech to discover disulfide constrained peptides (DCPs) for targets of interest. Active areas of research include development of diverse peptide libraries using display-based selection technologies and using these libraries to identify peptide leads with drug-like properties, performing next generation sequencing, validation of synthetically made DCPs and optimization of properties to evolve peptide lead hits. This position provides an opportunity to learn/apply in-house selection technologies (phage display, mRNA display, etc.), a variety of biophysical techniques, peptide rational design, and peptide structure determination using NMR spectroscopy.
Qualifications:
* Qualified candidates must have a Ph.D. in Chemistry, Biochemistry, Chemical Biology, or a related discipline.
* A successful candidate will be passionate and curious about developing selection platforms for discovery of peptide leads.
* You need to be highly motivated and able to work effectively in a very collaborative research environment.
* Skills in molecular biology, biochemistry techniques and biophysical assays (ELISA, PCR, SPR) as evidenced by a first author paper published or accepted in a peer-reviewed journal are desired.
* Experience in peptide NMR spectroscopy, peptide chemistry, display screening technologies, such as phage, mRNA and yeast display, or high throughput screening is a plus.
* Strong problem solving, communication and organizational skills are highly desirable.
For more information about the postdoctoral program at Genentech, please visit our postdoc information website at: https://careers.gene.com/us/en/students-postdocs
For more information on Fairbrother Lab please visit:
https://www.gene.com/scientists/our-scientists/wayne-fairbrother
The expected salary range for this position based on the primary location of California is $64,800 and $120,300. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed at the link provided below.
Benefits
Relocation benefits are available for this job posting.
#postdoc
Who we are
A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.
Unless entitled to a reasonable accommodation under applicable law, employees are required to be fully vaccinated against COVID-19 in accordance with customer requirements, the company's health and safety obligations and/or applicable law or guidelines.
Diversity and Inclusion (D&I) are critical to the success of our company and our impact on society. We believe that by championing diversity of background, thought and experience, we can foster a sense of belonging and provide an environment where every employee feels valued, included, and able to contribute their best for the patients we serve. We're focused on attracting, retaining, developing and advancing our people to their full potential by rewarding bold ways of thinking and integrating inclusive behaviors into every aspect of our work.
Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status and veteran status. For more information about equal employment opportunity, visit our Genentech Careers Homepage.$64.8k-120.3k yearly11d ago
We are looking for a highly motivated, productive, and talented postdoctoral fellow with a strong background in Immunology, fibrosis and/or tissue wound healing response. The fellow will join a team focusing on pathophysiology of pro-inflammatory and/or fibrotic diseases in the Immunology Discovery Department.$64.8k-120.3k yearly35d ago
Postdoctoral Fellow, Cancer Immunology, Oh Lab
The Position
We are looking for an enthusiastic, motivated postdoctoral research fellow to join the Oh Lab in the Cancer Immunology department at Genentech.
The goal of this research position is to examine how checkpoint inhibition, with a particular focus on the PD-1/PD-L1 pathway, impacts the dynamics of the tumor-specific T cell receptor (TCR) repertoire, and its subsequent impact on T cell priming, differentiation, and function. Additional areas of exploration will center around how T cell interactions with antigen presenting cells in the tumor influence the development of productive anti-tumor immune responses. Greater insight into the characteristics of the tumor-specific TCR repertoire and CD8+ T cell phenotypes that drive productive anti-tumor responses will have important implications not only for the development of adoptive cell therapies, but will also enhance our understanding of other efficacious therapies.
The cutting-edge research environment at Genentech provides access to advanced experimental and computational technologies, opportunities to collaborate with scientists from many different disciplines, and exposure to process of drug/therapeutic development.
Qualifications:
* Candidates must be a recent or upcoming graduate of a Ph.D. program in Immunology, Molecular Biology, Cell Biology or related biological science.
* Expertise in T cell biology is highly desired.
* A strong record of scientific accomplishments including impactful peer-reviewed first author paper(s).
* Strong oral and written communication skills, and willingness to work in a highly collaborative environment is required.
* Expertise in multi-dimensional flow cytometry, in vivo models, and single cell analysis technologies is highly desired.
For more information about the postdoctoral program at Genentech, please visit our postdoc information website at: https://careers.gene.com/us/en/students-postdocs
For more information on Dr. Oh please visit:
https://www.gene.com/scientists/our-scientists/soyoung-oh
The expected salary range for this position based on the primary location of California is $64,800 and $120,300. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed at the link provided below.
Benefits
Relocation benefits are available for this job posting.
#postdoc
Who we are
A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.
Unless entitled to a reasonable accommodation under applicable law, employees are required to be fully vaccinated against COVID-19 in accordance with customer requirements, the company's health and safety obligations and/or applicable law or guidelines.
Diversity and Inclusion (D&I) are critical to the success of our company and our impact on society. We believe that by championing diversity of background, thought and experience, we can foster a sense of belonging and provide an environment where every employee feels valued, included, and able to contribute their best for the patients we serve. We're focused on attracting, retaining, developing and advancing our people to their full potential by rewarding bold ways of thinking and integrating inclusive behaviors into every aspect of our work.
Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status and veteran status. For more information about equal employment opportunity, visit our Genentech Careers Homepage.$64.8k-120.3k yearly26d ago
Postdoctoral Research Fellow, Antibody Engineering, Spiess Lab
We are seeking a talented Postdoctoral Research Fellow to join the Antibody Engineering Department.$64.8k-120.3k yearly15d ago
Clinical Fellow Neuroscience and Immunology, Infectious Diseases, and Ophthalmology therapeutic area(s)
The Position
2 year Fellowship in Product Development Clinical Science (Neuroscience and/or
Immunology, Infectious Diseases, and Ophthalmology therapeutic area(s)
The Roche Pharma Development Clinical Science Fellowship aims to recruit high quality MD, PhD or MD/PhD graduates within Life Sciences for specialist training in the late stage Neuroscience (PDN) and Immunology, Infectious Diseases, and Ophthalmology (I2O) clinical science development groups.
The program has been designed to diversify and broaden academic training through exposure to clinical trial methodology and cross-functional teams operating globally working with internal experts in the field at Roche.
The fellowship will be 2 years in duration, primarily based at Roche Headquarter Basel, CH, within the clinical science development groups, which are responsible for the strategy, design and execution, and result interpretation of late phase clinical trials. This position is within the Translation and Technology Research team which aims to use technology and innovation to work on clinical questions to accelerate clinical development. This project will work on an interface between neurosciences and ophthalmology.
As a Fellow at Roche you may:
Be involved in the design, execution, analysis and interpretation of data from studies for using novel technologies.
Participate in key clinical strategy, implementation meetings in order to gain a deeper understanding of the complexities and challenges of the development of new medicines.
Generate and present abstracts and oral presentations for key external conferences and other specialty meetings as well as publication opportunities.
Be involved in discussions and activities around Clinical Science Innovation.
For whom is the Roche PD Clinical Science Fellowship suitable for?
Highly motivated PhD graduates in Life Sciences, MD or MD/PhD with interest in innovation in clinical research.
A strong team player with an agile mind-set and looking to diversify their career skills.
Interested in further understanding and influencing the development and approval of medicines for patients.
Good understanding of Neuroscience (PDN) and/or Ophthalmology (I2O) diseases is preferred.
Excellent English skills, written and spoken.
Previous clinical research experience is advantageous.
Why a Pharmaceutical Industry Fellowship?
Collaborations between pharmaceutical companies, the health service and academia are key to improving patient outcomes and care and enhance bi-directional transfer of scientific knowledge.
Gain understanding and acquiring insights into drug development, regulation and the reimbursement process.
Our fellowship offers a unique training for those wishing to participate or conduct clinical trials in their future careers.
Application process
Phase 1: CV & Cover Letter screen
Phase 2: Virtual Interviews
As part of your cover letter, Roche wants to understand your motivation in applying for this position. You should, therefore, provide responses to the following:
Your key motivation for applying to this placement
What skills and experience will you bring to the role
What personal qualities will you bring to the role
Your interests and activities outside work and study
Your cover letter should not exceed one page.
Who we are
At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we've become one of the world's leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.
Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more.
Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.
We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.
Roche is an Equal Opportunity Employer.$82k-105k yearly est.6d ago
Sr. Principal Scientist - Translational Medicine Digital Pathology
The expected salary range for this position based on the primary location of South San Francisco, CA is $169,800-315,300.$169.8k-315.3k yearly19d ago
Senior Principal Bioinformatics Scientist, NGS Algorithms
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Scientist 3, Immunology Discovery
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