Scientist jobs at Fresenius Kabi - 1049 jobs

When you join the growing BILH team, you're not just taking a job, you're making a difference in people's lives.Individual has progressed beyond the Research Fellow/Trainee stage and is functioning at the independent Principal Investigator level. Incumbent in this position may be in the entry to more senior level at varying degrees of independence. Must have been awarded or have completed the requirements for a doctoral degree or foreign equivalent.Job Description:Essential Responsibilities: Conducts research in area of specialty.Has the authority to direct and support managers with functional area responsibilities.Has the direct responsibility to undertake the following employment actions: hiring, termination, corrective action and performance reviews.Has full responsibility for planning, monitoring and managing department budget.Direct Reports: None Indirect Reports: NoneRequired Qualifications- Ph.D. and/or Medical Degree required.- 0-1 years related work experience required, including, 1 year of supervisory/management experience required.- Advanced technical computer skills as required for technical support specific to functional area and related systems.Competencies:Written Communications: Ability to communicate complex information in English effectively in writing to all levels of staff, management and external customers across functional areas.Oral Communications: Ability to verbally communicate complex concepts in English and address sensitive situations, resolve conflicts, negotiate, motivate and persuade others.Knowledge: Ability to demonstrate broad and comprehensive knowledge of theories, concepts, practices and policies with the ability to use them in complex and/or unprecedented situations across multiple functional areas.Teamwork: Ability to lead and direct multiple collaborative teams for large projects or groups both internal and external to the Medical Center and across functional areas. Results have significant implications for the management and operations of the organization.Customer Service: Ability to lead operational initiatives to meet or exceed customer service standards and expectations in assigned unit(s) and/or across multiple areas in a timely and respectful manner.Physical Nature of the Job:Light work: Exerting up to 20 pounds of force frequently to move objects. Some elements of the job are sedentary, but the employee will be required to stand for periods of time or move throughout the hospital campus. Pay Range: $60,320.00 USD - $150,009.60 USDThe pay range listed for this position is the annual base salary range the organization reasonably and in good faith expects to pay for this position at this time. Actual compensation is determined based on several factors, that may include seniority, education, training, relevant experience, relevant certifications, geography of work location, job responsibilities, or other applicable factors permissible by law. As a health care organization, we have a responsibility to do everything in our power to care for and protect our patients, our colleagues and our communities. Beth Israel Lahey Health requires that all staff be vaccinated against influenza (flu) as a condition of employment.More than 35,000 people working together. Nurses, doctors, technicians, therapists, researchers, teachers and more, making a difference in patients' lives. Your skill and compassion can make us even stronger.Equal Opportunity Employer/Veterans/Disabled

A leading healthcare institution in Boston seeks a Sr. Principal Scientist to oversee operations in a GMP lab, focusing on the production and quality control of radiopharmaceuticals. The ideal candidate will have extensive experience in aseptic operations, knowledge of QC methodologies, and a strong educational background in pharmaceuticals. This role requires meticulous documentation, adherence to GMP standards, and the ability to thrive in a fast-paced environment, contributing to pioneering advancements in patient care. #J-18808-Ljbffr

Our mission at Asimov is to advance humanity's ability to design living systems, enabling biotechnologies with outsized benefit to society. We're developing a mammalian synthetic biology platform--from cells to software--to enable the design and manufacture of next-generation therapeutics. We are seeking a Senior Research Associate to join our DNA & Strain Construction team in Boston, MA. The ideal candidate will have a proven track record designing and constructing plasmids, using different assembly strategies. They will be a key contributor to our team, working closely with other DNASC team members using the latest molecular biology and automation techniques to help advance our high throughput DNA construction pipeline, at the same pushing the limits of DNA assembly capabilities. They will also work closely with Asimov's Synthetic Biology, High Throughput and Cell Line Development teams. This is a unique opportunity to work at a nimble, forward-thinking synthetic biology startup and help build the foundation for engineering biology. About the Role: * Conduct PCR, Golden Gate or Gibson Assembly, plasmid purification, and sequencing prep to validate DNA constructs, both manually and in high-throughput using liquid handlers (e.g., Echo, Bravo, Hamilton STAR) following Standard Operation Procedures (SOPs) * Contribute to vector assembly design, and remediation plans. * Work with your manager to generate regulatory reports to support our customers' needs. * Maintain accurate sample tracking and documentation in LIMS to ensure data integrity and reproducibility. * Assist with large-scale plasmid preparations (LSPs) to support internal and external projects. * Collaborate with scientists and other RAs to troubleshoot workflows, improve efficiency and develop new initiatives within the team. * Work as part of a multifunctional team, you'll partner with synthetic biologists on the DNASC team as well as members of the Cell Line Development, Synthetic Biology and Software Development teams. About You: * You have a B.S. or M.S. degree in biology, biochemistry, biological engineering, or a related field. * Deep bench experience is necessary to be successful in this role, and you will have 3+ years of biopharma experience. * You value teamwork and are motivated to contribute to the team's goals. * Working as part of a highly integrated research team is exciting to you. * Automation experience is a plus but a desire to learn to develop automation of lab experiments is a must. * You will have independently or collaboratively designed an assembly plan to generate plasmids using either Gibson or Golden Gate. * You have experience, outside of coursework, with modern molecular biology and/or microbiological techniques such as various DNA assembly methods (Golden Gate, Gibson), PCR, colony picking, and DNA preps. * Being detail-oriented isn't just a sound bite for you, it's part of your DNA. * Experience with optimizing cloning protocols (PCR, Gibson, and especially Golden Gate) and basic mammalian cell culture techniques is a plus. * Experience extracting data using scripts from large databases or desire to learn is a plus. * We're big on tools here! We're happy to train you but if you know your way around Benchling, LIMS, Google Drive, and Excel, it'll help you come up to speed quickly. We're fueled by a vision to transform biological engineering into a fully-fledged engineering discipline. Should you join our team, you will grow with a constantly evolving organization and push the frontiers of synthetic biology. Company culture is key to Asimov, and ours is a culture of recombination; we believe that our mission can only be achieved by bringing together a diverse team with a mixture of backgrounds and perspectives.

Senior Behavioral Scientist, Nudge Unit & Behavioral Insights page is loaded## Senior Behavioral Scientist, Nudge Unit & Behavioral Insightslocations: Bostontime type: Full timeposted on: Posted 2 Days Agojob requisition id: R07992## **What We Need**In May 2020, BCBSMA formed an internal nudge unit, led by its Performance Measurement and Improvement (PMI) division, and assisted by consultants and selected academics. Since its inception, the BCBSMA nudge unit has deployed over 100 behavioral insights-informed interventions, preferring randomized deployments to maximize evaluability. These interventions have included efforts to improve guideline-concordant screening uptake, medication use, laboratory testing, and provider billing patterns. Intervention channels include unidirectional communications (e.g., letters, emails, text messages, faxes) and more complex choice architecture (e.g., BCBSMA's member app, which has more than 1 million users).Reporting to the Director, Nudge Unit, Behavioral Insights & Strategic Research, the Senior Behavioral Scientist will support the company's efforts to apply behavioral insights (i.e., “nudges” and other behavioral insights techniques) to improve the decisions, experiences, and health of BCBSMA's members, network providers, and employees. All nudge unit activities will further BCBSMA's strategic pillars: quality, equity, affordability, and consumer experience.The Senior Behavioral Scientist will, in collaboration with the Director as well as the SVP of Performance Measurement and Improvement, support the growth of BCBSMA's nudge unit and application of behavioral insights. Specific duties will include providing cross-divisional leadership in a matrixed organization, mentoring more junior nudge unit staff, tracking and managing multiple projects and their evaluations, facilitating trainings in behavioral insights techniques, and working with BCBSMA's behavioral insights consultants and academic collaborators.**Your Day to Day*** Lead all phases of nudge unit projects and their evaluations, helping to organize evaluation results and track projects to facilitate better nudge unit performance over time.* Help to coordinate Nudge Unit activities across multiple business units, consultants, and vendors to apply behavioral insights toward BCBSMA's strategic goals.* Design and execute mixed methods research using a wide variety of methods (e.g. qualitative research, A/B testing, RCTs, pre-post evaluations) to provide deep consumer and behavioral insights.* Communicate with external experts and collaborators on behavioral insights activities.* Train and mentor other internal nudge unit staff on the application of behavioral insights.* Create presentations for executive meetings, support and/or represent the Director in senior leadership meetings, as needed.*This document is not an exhaustive list of all responsibilities, skills, duties, requirements, or working conditions associated with the job. Employees may be required to perform other job-related duties.***We're Looking for:*** Demonstrated understanding of behavioral science principles and their application in healthcare.* Familiarity with program evaluation methods, causal inference, A/B testing, and Agile project management desired.* Proven track record of delivering highly complex initiatives in a dynamic environment.* Ability to direct, persuade, influence, and lead to achieve desired results.* Outstanding communication skills and demonstrated ability to develop and maintain effective working relationships at all levels.* Ability to motivate, lead and manage cross functional teams, with track record of coaching high-performing teams.* Solid background in project management and implementation of major initiatives.* Flexibility to work within a changing environment.* High degree of initiative; ability to work both independently and within a team.**What You Bring:*** Minimum of 8 years of experience in consulting, applied research, healthcare, insurance, or related industry.* Training and experience in practical applications and evaluation of behavioral insights strongly preferred.* Bachelor's Degree Required; Master's or PhD Degree in Economics, Behavioral Science, Psychology, or related field strongly preferred.* Direct experience leading and managing staff preferred.This position is eligible for the following personas: eWorker, Mobile, Resident.## Minimum Education Requirements:High school degree or equivalent required unless otherwise noted above## LocationBoston## Time TypeFull time Salary Range: $123,930.00 - $151,470.00 The job posting range is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. We may ultimately pay more or less than the posted range, and the range may be modified in the future. An employee's pay position within the salary range will be based on several factors including, but limited to, relevant education, qualifications, certifications, experience, skills, performance, shift, travel requirements, sales or revenue-based metrics, and business or organizational needs and affordability.This job is also eligible for variable pay.We offer comprehensive package of benefits including paid time off, medical/dental/vision insurance, 401(k), and a suite of well-being benefits to eligible employees.Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, or any other form of compensation that are allocable to a particular employee remains in the Company's sole discretion unless and until paid and may be modified at the Company's sole discretion, consistent with the law.We understand that the and can prevent amazing candidates coming our way, so please don't hesitate to apply. We'd love to hear from you. You might be just what we need for this role or possibly another one at Blue Cross Blue Shield of MA. The more voices we have represented and amplified in our business, the more we will all thrive, contribute, and be brilliant. We encourage you to bring us your true colors, , your perspectives, and your experiences. It's in our differences that we will remain relentless in our pursuit to transform healthcare for ALL.As an employer, we are committed to investing in your development and providing the necessary resources to enable your success. Learn how we are dedicated to creating an inclusive and rewarding workplace that promotes excellence and provides opportunities for employees to forge their unique career path by visiting our page. If this sounds like something you'd like to be a part of, we'd love to hear from you. You can also join our to stay “in the know” on all things Blue.At Blue Cross Blue Shield of Massachusetts, we believe in wellness and that work/life balance is a key part of associate wellbeing. For more information on how we work and support that work/life balance visit our "" Page.Voted as the highest in member satisfaction among Massachusetts commercial health plans by JD Power, Blue Cross Blue Shield of Massachusetts is a community-focused, tax-paying, not-for-profit health plan headquartered in Boston. We have been a market leader for over 75 years, and are consistently ranked among the nation's best health plans. Our daily efforts are dedicated to effectively serving our 2.8 million members, and consistently offering security, stability, and peace of mind to both our members and associates.## **Our Commitment to You**We are committed to investing in your development and providing the necessary resources to enable your success. We are dedicated to creating a refreshing and rewarding workplace that promotes excellence and provides opportunities for employees to forge their unique career path. We take pride in our diverse, community-centric, wellness-focused culture #J-18808-Ljbffr

Quality Control Chemist II At Country Life, we inspire greatness through our wholistic approach of supplement and personal care products. Our team of experts, innovators and dreamers is dedicated to bringing the power of nature and the promise of science to people at every life stage. Join our Hauppauge, NY team and share our passion for natural health and pride in our company's commitment to excellence and quality! Position Summary: Testing pharmaceuticals, vitamins and herbal products using HPLC, ICP, FTIT, NIR, UV-VIS and wet chemistry per USP, AOAC, FCC, BP (British Pharmacopeia) and internal procedures. Properly disposes of waste chemicals based on OSHA requirements. Position Scope: Handles approximately 15 - 35 analytical tests per week Position Responsibility: Works with lab instruments, e.g. HPLC, AA, PDA, RI detection methods, ICP and ICP-MS to perform analytical tests. Also works with chemicals and reagent solvents during the day. Records the raw data and results from scientific test results. Reports any lab instruments malfunction to Lab Manager. Prepares and files all Quality Control documents, e.g. Certificate of Analysis (COA) Deviations, Out of Specification (OOS) reports. Reviews testing and notebooks to prepare bulk product release. Conducts daily calibration of balances and Ph meter. Calibrates an expiration date for all product labels based on shelf life expectancy. Disposes of waste chemicals appropriately. Checks raw materials and finished product potencies. Proper disposal of expired raw materials, in-process and finished goods (final batches). Coordinates such activities with Safety Manager. Prepares samples for shipment to outside testing laboratory. Assists in the inventory of supplies and upkeep of laboratory and laboratory machinery. Preparation of purchase orders, receipt of supplies, and interfacing with other departments to expedite these functions. Chemist II: in additional to the above Qualification and maintenance of primary and secondary standards of raw material and finished products. Maintains R&D raw material inventory, laboratory notebooks, equipment logs and maintenance schedules. Prepares specification for raw materials and finished products. Conducts in process testing of manufactured samples. Conducts minor repairs of lab instruments and other apparatus. Supports the preparation, manufacture, evaluation and documentation of new or modified R&D in-process and finished products associated with Country Life formulations, e.g., tablets, capsules and powders. Writes detailed scientific instructions and lab procedures. Senior Chemist: in additional to the above Develops analytical methods and validations. Analyses, records and releases raw materials and conducts maintenance of raw material specifications. Maintains lab chemicals for consistency to standards (e.g. USP, GLP and OSHA). Performs analytical troubleshooting and updates SOPs, log books and lab solutions preparation book. Provides guidance and training for Chemists I and II. General Clean working space, desk, equipment/glassware and whole lab. Must wear Personal Protective Equipment (PPE) at all times as stipulated by SOPs. e.g. respirator, ear plugs, hair net, beard cover and lab coat. Lifting up to 20 lbs. may be required. Position requires considerable standing on lab floor. Maintains professional and technical knowledge by attending educational symposia; reviewing professional publications; establishing personal networks; participating in professional societies, etc. Satisfactory completion of appropriate corporate training as related to the position and/or department. Assures compliance by following Food and Drug Administration's Good Manufacturing Practices (FDA cGMPs / GLPs) as well as other regulatory standards as required by the department. Contributes to overall achievement by accomplishing related tasks and demonstrating characteristics that exemplify team building and support. The above is not intended to be an all-inclusive list of responsibilities. Other activities may be assigned as required by management. QUALIFICATIONS Experience and Skills: Chemist I will have one year Pharmaceutical laboratory or related experience as well as good mechanical aptitude. Training on specific laboratory equipment and instruments is preferred and may be provided if no work experience outside of classroom laboratory Chemist II will have three years of Pharmaceutical lab experience and good familiarity with HPLC, ICP and ICP-MS as well as good mechanical aptitude. Senior Chemist will have five years Pharmaceutical lab experience and strong experience with HPLC, ICP and ICP-MS as well as good mechanical aptitude. Good organizational skills. Good interpersonal skills. Excellent knowledge of PC software, MS Office, Word, Excel. Good written and verbal communication skills. Excellent Chemistry background as well as practical application of the technical knowledge. Excellent understanding and attitude towards cGMP and GLP, which will increase with job level. Education and Certifications: Undergraduate degree in Chemistry required for Chemist I and Chemist II positions. Masters of Chemistry, or equivalent, is preferred for Senior

Are you an internal caregiver, student, or contingent worker/agency worker at UMass Memorial Health? CLICK HERE to apply through your Workday account. Exemption Status: Non-Exempt Hiring Range: $39.96 - $71.92 Please note that the final offer may vary within this range based on a candidate's experience, skills, qualifications, and internal equity considerations. Schedule Details: Monday through Friday, Weekends (Saturday and Sunday) Scheduled Hours: Varies Shift: 1 - Day Shift, 8 Hours (United States of America) Hours: 0 Cost Center: 34000 - 3411 IVF This position may have a signing bonus available a member of the Recruitment Team will confirm eligibility during the interview process. Everyone Is a Caregiver At UMass Memorial Health, everyone is a caregiver - regardless of their title or responsibilities. Exceptional patient care, academic excellence and leading-edge research make UMass Memorial the premier health system of Central Massachusetts, and a place where we can help you build the career you deserve. We are more than 20,000 employees, working together as one health system in a relentless pursuit of healing for our patients, community and each other. And everyone, in their own unique way, plays an important part, every day. Position Summary: Perform various embryological medical procedures, including IVF and fertility analysis. Major Responsibilities: Counsel and advise patients on fertility and ART (Assisted Reproductive Technology) procedures. Treat infertility issues using ART. Oversee day-to-day technical and administrative aspects of IVF lab operation under the direction of IVF Laboratory Director. Technical benchwork, quality control and quality assurance activities and paperwork. Train newly hired embryologists. Work closely with the lab director and medical director to assure quality patient care and compliance with regulatory and accrediting agencies. Resolve technical problems including equipment troubleshooting following manufacturer's instructions and/or in accordance with policies and procedures approved by the laboratory director. Review, revise, and write IVF laboratory protocols. All responsibilities are essential job functions. Position Qualifications: License/Certification/Education: Required: Bachelor's degree in chemical, physical, biological, medical technology, clinical or reproductive laboratory science from an accredited institution. Preferred: Master's degree in chemical, physical, biological, medical technology, clinical or reproductive laboratory science from an accredited institution. Certification as Technical Supervisor (American Board of Bioanalysis). Experience/Skills: Required: Experience of at least 3 years in all IVF procedures including, ICSI, AH, vitrification, blastocyst biopsy and other related procedures. Be proficient in all IVF procedures including intracytoplasmic sperm injection (ICSI), Assisted hatching (AH), embryo/blastocyst vitrification, blastocyst biopsy, biopsied cell processing for PGT, oocyte vitrification and warming. Knowledge to conduct CAP, FDA, and CLIA inspections. Excellent communication, both verbal and written Basic computer skills necessary for data entry, making data summary tables/spreadsheets and operating electronic medical record. Must be detail oriented and a team player. Preferred: Unless certification, licensure or registration is required, an equivalent combination of education and experience which provides proficiency in the areas of responsibility listed in this description may be substituted for the above requirements. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status. We're striving to make respect a part of everything we do at UMass Memorial Health - for our patients, our community and each other. Our six Standards of Respect are: Acknowledge, Listen, Communicate, Be Responsive, Be a Team Player and Be Kind. If you share these Standards of Respect, we hope you will join our team and help us make respect our standard for everyone, every day. As an equal opportunity and affirmative action employer, UMass Memorial Health recognizes the power of a diverse community and encourages applications from individuals with varied experiences, perspectives and backgrounds. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, sexual orientation, national origin, age, disability, gender identity and expression, protected veteran status or other status protected by law. If you are unable to submit an application because of incompatible assistive technology or a disability, please contact us at ***********************************. We will make every effort to respond to your request for disability assistance as soon as possible.

The Company We are Alloy Therapeutics-a biotechnology ecosystem company empowering the global scientific community to make better medicines together. Through a community of partners, we democratize access to pre-competitive tools, technologies, services, and company creation capabilities that are foundational for discovering and developing therapeutic biologics. The company facilitates affordable, non-exclusive access to the entire drug discovery community from academic scientists, small and medium biotech, to the largest biopharma. At Alloy, we believe our industry should compete on getting the best drugs to patients as quickly as possible, not exclusive access to the best platforms. As a reflection of our relentless commitment to the scientific community, we reinvest 100% of our revenue in innovation and access to innovation. MAY THE BEST DRUG WIN. Alloy is headquartered in Waltham, MA with additional labs in Cambridge, UK; Basel, Switzerland, and Athens, GA. Successful members thrive in our shared culture of accountability, deliberate trust, and open communication. As a team we aspire to work together to exceed expectations and collectively contribute across the global organization to always maintain our nimble, startup culture. This is an on-site and full-time position in Waltham, MA. At Alloy, we have an ethos of “Mentorship-By-Apprenticeship” in all of our positions. We strive to have workers in the office when needed to interact organically and face-to-face. Of course, as a lab-based operation, our cells and animals grow 7 days a week, 365 days per year. We respect and value our colleagues for their hard work that requires them to be in the lab every day. We ask our people who have more flexible accommodations, like this position, to appreciate their colleagues who have less flexibility. We are all one team! The Team The Alloy Genetic Medicines group is innovating a novel RNA-based drug discovery platform, namely “AntiClastic”, spanning the fields of antisense therapeutics to immunomodulating therapeutics. This technology platform was launched by Alloy in 2023 after exclusively licensing its underlying intellectual property which implements a novel spatial conformation of the oligonucleotide developed by Sudhir Agrawal of Arnay Sciences. The team works closely with external partners to discover and develop AntiClastic RNA medicines. The Role This position reports to the Head of Nucleic Acid Chemistry. We are seeking a detail-oriented Nucleic Acid Chemistry Scientist to join our growing Nucleic Acid Chemistry team supporting the CMC development of oligonucleotides, mRNA, pDNA templates, and antibody-oligonucleotide conjugates (AOCs). The successful candidate will bring strong hands-on expertise in synthesis and purification of nucleic acids, as well as HPLC and LC-MS analytics for RNA, DNA, and nucleic acid medicines. You will have a proven track record of developing, documenting, qualifying, and troubleshooting analytical methods and production processes in a fast-paced industrial environment. This role also requires experience working with and managing Contract Research Organizations (CROs), and developing/synthesizing reference materials to enable method development and program progression. This role may be filled at Scientist I or Scientist II depending on experience and demonstrated level of independence. Principal Responsibilities Synthesis and Process Development pDNA Production: Execute microbial fermentation (E. coli) for plasmid DNA amplification; perform harvesting, lysis, and purification of pDNA. Linearization: Perform enzymatic restriction digests to linearize pDNA templates for downstream transcription. mRNA Synthesis: Lead in vitro transcription (IVT) reactions to produce mRNA, including enzymatic capping (Cap 1) and poly-adenylation. Oligonucleotide: Execute procedures to synthesize oligonucleotides. Purification: Utilize TFF (Tangential Flow Filtration) and chromatography (IEX, HIC, or Affinity) to purify intermediates and finished products from process-related impurities. Analytical Method Development & Qualification Develop, optimize, document, qualify, and transfer phase-appropriate analytical methods to support CMC activities for oligonucleotides, mRNA, pDNA, and AOCs. Design fit-for-purpose methods for identity, purity, integrity, potency/assay, and stability, including forced-degradation studies. Lead method qualification/verification activities for nucleic acid CQAs (e.g., product related purity, drug antibody ratios, mRNA capping efficiency, poly-A tail length, and residual template DNA). Execute and interpret analyses using HPLC/UPLC modalities (e.g., IPRP, AE, IEX, HILIC, SEC). Perform and interpret LC-MS analyses for intact oligos, mRNA mapping, sequence confirmation, impurity ID, and conjugate characterization. Independently troubleshoot instrument and method issues, ensuring data integrity and project continuity. Reference Materials Development Develop, qualify, and maintain analytical reference materials (e.g., standards, system suitability controls, impurity markers) to support method development, stability programs, and release testing. Coordinate and/or perform internal synthesis (chemical or enzymatic) of oligonucleotide and mRNA reference materials and related controls. CRO / External Partner Management Work effectively with and manage CRO/CDMO partners executing analytical studies, method development, or mRNA/pDNA manufacturing. Author, review, and approve CRO protocols, reports, data packages, and method documentation. Documentation & Data Integrity Document experiments in real time with excellent attention to detail in electronic lab notebooks. Support regulatory-compliant documentation for IND/BLA/MAA filings and respond to technical inquiries. Qualifications Ph.D. in Analytical Chemistry, Biochemistry, Molecular Biology, or related field with 2-5 years of industry experience in nucleic acid synthesis or analytical development. Hands-on experience in pDNA, mRNA, and oligonucleotide production: Including microbial fermentation, pDNA purification, linearization, and in vitro transcription (IVT), solid-phase synthesis, & lyophilization. Extensive hands-on experience with HPLC/UPLC and LC-MS applied to mRNA, pDNA, oligonucleotides, and/or oligonucleotide conjugates. Demonstrated success developing and qualifying analytical methods for nucleic acids (e.g., Capillary Electrophoresis/Fragment Analyzer for mRNA integrity). Experience developing, synthesizing/sourcing, characterizing, and maintaining reference materials/standards. Proven experience working with and managing CRO and/or CDMO partners. Strong understanding of nucleic acid challenges (e.g., RNase-free handling, secondary structures, ion-pairing reagents, sequence variants, and conjugation heterogeneity). Experience with antibody-oligonucleotide conjugates (AOCs) and LNP-formulated mRNA. (Preferred) Familiarity with GMP/GLP environments and regulatory expectations for method lifecycle management. (Preferred) Hands-on knowledge of complementary techniques (e.g., qPCR/dd PCR, SEC-MALS, and biophysical assays). (Preferred) Taking Care of Our People We support the individuality of what people need to do outside of work to empower them to do their best at work. While you focus on making better medicine together , we focus on programs and benefits that support a diverse and growing team. Whether you're single, in a growing family, or nearing retirement, Alloy offers a variety of comprehensive and competitive benefits starting from day one. Compensation Competitive base and equity compensation commensurate with level of experience and independence 401(k) company match Health & Family Generous personal and family medical, dental and vision benefits with 100% of premiums and deductibles covered Company-paid disability (STD, LTD) and life insurance Paid parental leave Family planning support up to $45,000 (e.g., IVF/PGT, adoption, surrogacy, egg retrieval) Unique Perks Unlimited PTO (paid time off) and flexible schedules Annual stipend for continuing education with commitment to your career through individualized professional development plan Wellness and Extensive Employee Assistance Program (EAP) including resources for mental wellness Pay Transparency At Alloy Therapeutics, we believe in fostering trust and open communication. For this role, the estimated annual base salary range is $126,000 - $144,000 with the final offer based on factors like your experience, skills, and alignment with our needs. Additionally, this role is eligible for equity compensation, reflecting our commitment to shared success as we work together to make better medicines. We are proud to offer competitive compensation and benefits, aiming to support our team's professional and personal well-being. If you have any questions about pay or benefits, we're here to help. Alloy Therapeutics is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, sexual orientation, gender identity, veteran status, disability, or other legally protected status. If you are unable to submit an application because of incompatible assistive technology or a disability, please contact us at [email protected] . We will make every effort to respond to your request for disability assistance as soon as possible.

The Company We are Alloy Therapeutics-a biotechnology ecosystem company empowering the global scientific community to make better medicines together. Through a community of partners, we democratize access to pre-competitive tools, technologies, services, and company creation capabilities that are foundational for discovering and developing therapeutic biologics. The company facilitates affordable, non-exclusive access to the entire drug discovery community from academic scientists, small and medium biotech, to the largest biopharma. At Alloy, we believe our industry should compete on getting the best drugs to patients as quickly as possible, not exclusive access to the best platforms. As a reflection of our relentless commitment to the scientific community, we reinvest 100% of our revenue in innovation and access to innovation. MAY THE BEST DRUG WIN. Alloy is headquartered in Waltham, MA with additional labs in Cambridge, UK; Basel, Switzerland, and Athens, GA. Successful members thrive in our shared culture of accountability, deliberate trust, and open communication. As a team we aspire to work together to exceed expectations and collectively contribute across the global organization to always maintain our nimble, startup culture. This is an on-site and full-time position in Waltham, MA. At Alloy, we have an ethos of "Mentorship-By-Apprenticeship" in all of our positions. We strive to have workers in the office when needed to interact organically and face-to-face. Of course, as a lab-based operation, our cells and animals grow 7 days a week, 365 days per year. We respect and value our colleagues for their hard work that requires them to be in the lab every day. We ask our people who have more flexible accommodations, like this position, to appreciate their colleagues who have less flexibility. We are all one team! The Team The Alloy Genetic Medicines group is innovating a novel RNA-based drug discovery platform, namely "AntiClastic", spanning the fields of antisense therapeutics to immunomodulating therapeutics. This technology platform was launched by Alloy in 2023 after exclusively licensing its underlying intellectual property which implements a novel spatial conformation of the oligonucleotide developed by Sudhir Agrawal of Arnay Sciences. The team works closely with external partners to discover and develop AntiClastic RNA medicines. The Role This position reports to the Head of Nucleic Acid Chemistry. We are seeking a detail-oriented Nucleic Acid Chemistry Scientist to join our growing Nucleic Acid Chemistry team supporting the CMC development of oligonucleotides, mRNA, pDNA templates, and antibody-oligonucleotide conjugates (AOCs). The successful candidate will bring strong hands-on expertise in synthesis and purification of nucleic acids, as well as HPLC and LC-MS analytics for RNA, DNA, and nucleic acid medicines. You will have a proven track record of developing, documenting, qualifying, and troubleshooting analytical methods and production processes in a fast-paced industrial environment. This role also requires experience working with and managing Contract Research Organizations (CROs), and developing/synthesizing reference materials to enable method development and program progression. This role may be filled at Scientist I or Scientist II depending on experience and demonstrated level of independence. Principal Responsibilities Synthesis and Process Development * pDNA Production: Execute microbial fermentation (E. coli) for plasmid DNA amplification; perform harvesting, lysis, and purification of pDNA. * Linearization: Perform enzymatic restriction digests to linearize pDNA templates for downstream transcription. * mRNA Synthesis: Lead in vitro transcription (IVT) reactions to produce mRNA, including enzymatic capping (Cap 1) and poly-adenylation. * Oligonucleotide: Execute procedures to synthesize oligonucleotides. * Purification: Utilize TFF (Tangential Flow Filtration) and chromatography (IEX, HIC, or Affinity) to purify intermediates and finished products from process-related impurities. Analytical Method Development & Qualification * Develop, optimize, document, qualify, and transfer phase-appropriate analytical methods to support CMC activities for oligonucleotides, mRNA, pDNA, and AOCs. * Design fit-for-purpose methods for identity, purity, integrity, potency/assay, and stability, including forced-degradation studies. * Lead method qualification/verification activities for nucleic acid CQAs (e.g., product related purity, drug antibody ratios, mRNA capping efficiency, poly-A tail length, and residual template DNA). * Execute and interpret analyses using HPLC/UPLC modalities (e.g., IPRP, AE, IEX, HILIC, SEC). * Perform and interpret LC-MS analyses for intact oligos, mRNA mapping, sequence confirmation, impurity ID, and conjugate characterization. * Independently troubleshoot instrument and method issues, ensuring data integrity and project continuity. Reference Materials Development * Develop, qualify, and maintain analytical reference materials (e.g., standards, system suitability controls, impurity markers) to support method development, stability programs, and release testing. * Coordinate and/or perform internal synthesis (chemical or enzymatic) of oligonucleotide and mRNA reference materials and related controls. * CRO / External Partner Management * Work effectively with and manage CRO/CDMO partners executing analytical studies, method development, or mRNA/pDNA manufacturing. * Author, review, and approve CRO protocols, reports, data packages, and method documentation. Documentation & Data Integrity * Document experiments in real time with excellent attention to detail in electronic lab notebooks. * Support regulatory-compliant documentation for IND/BLA/MAA filings and respond to technical inquiries. Qualifications * Ph.D. in Analytical Chemistry, Biochemistry, Molecular Biology, or related field with 2-5 years of industry experience in nucleic acid synthesis or analytical development. * Hands-on experience in pDNA, mRNA, and oligonucleotide production: Including microbial fermentation, pDNA purification, linearization, and in vitro transcription (IVT), solid-phase synthesis, & lyophilization. * Extensive hands-on experience with HPLC/UPLC and LC-MS applied to mRNA, pDNA, oligonucleotides, and/or oligonucleotide conjugates. * Demonstrated success developing and qualifying analytical methods for nucleic acids (e.g., Capillary Electrophoresis/Fragment Analyzer for mRNA integrity). * Experience developing, synthesizing/sourcing, characterizing, and maintaining reference materials/standards. * Proven experience working with and managing CRO and/or CDMO partners. * Strong understanding of nucleic acid challenges (e.g., RNase-free handling, secondary structures, ion-pairing reagents, sequence variants, and conjugation heterogeneity). * Experience with antibody-oligonucleotide conjugates (AOCs) and LNP-formulated mRNA. (Preferred) * Familiarity with GMP/GLP environments and regulatory expectations for method lifecycle management. (Preferred) * Hands-on knowledge of complementary techniques (e.g., qPCR/dd PCR, SEC-MALS, and biophysical assays). (Preferred) Taking Care of Our People We support the individuality of what people need to do outside of work to empower them to do their best at work. While you focus on making better medicine together, we focus on programs and benefits that support a diverse and growing team. Whether you're single, in a growing family, or nearing retirement, Alloy offers a variety of comprehensive and competitive benefits starting from day one. Compensation * Competitive base and equity compensation commensurate with level of experience and independence * 401(k) company match Health & Family * Generous personal and family medical, dental and vision benefits with 100% of premiums and deductibles covered * Company-paid disability (STD, LTD) and life insurance * Paid parental leave * Family planning support up to $45,000 (e.g., IVF/PGT, adoption, surrogacy, egg retrieval) Unique Perks * Unlimited PTO (paid time off) and flexible schedules * Annual stipend for continuing education with commitment to your career through individualized professional development plan * Wellness and Extensive Employee Assistance Program (EAP) including resources for mental wellness Pay Transparency At Alloy Therapeutics, we believe in fostering trust and open communication. For this role, the estimated annual base salary range is $126,000 - $144,000 with the final offer based on factors like your experience, skills, and alignment with our needs. Additionally, this role is eligible for equity compensation, reflecting our commitment to shared success as we work together to make better medicines. We are proud to offer competitive compensation and benefits, aiming to support our team's professional and personal well-being. If you have any questions about pay or benefits, we're here to help. Alloy Therapeutics is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, sexual orientation, gender identity, veteran status, disability, or other legally protected status. If you are unable to submit an application because of incompatible assistive technology or a disability, please contact us at [email protected]. We will make every effort to respond to your request for disability assistance as soon as possible.

Job Description Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing. Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates. Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need. The Position The Associate Scientist III works in the Chemistry, Manufacturing, and Controls Group focusing on oligonucleotide synthesis development. This is an ideal position for an individual with an organic chemistry background who has an interest in projects related to novel technology in synthesis and purification of oligonucleotides and bioconjugates. Responsibilities Work independently or with senior scientists to develop new synthetic approaches to desired compounds while keeping an eye toward large-scale synthesis Perform solid-phase synthesis and purification of oligonucleotide drug candidates Mentor others on internal protocols, practices and processes Analyze small-molecule and macromolecular targets using standard methods Recognize unusual circumstances, identify root cause(s) to problems, and begins providing recommendations to new approaches, techniques and/or practices Maintain a well-documented laboratory notebook Cerate an action plan with project deliverables with high-level guidance Track progress against project timelines, generate regular status updates, and communicate progress and issues to management, including presentation of findings at team meetings Independently coordinate delivery of materials both internally and externally Requirements MS in Chemistry or related field (minimum 2 years of relevant laboratory experience) or BS in Chemistry with 5+ years of experience Experience with synthetic organic chemistry Excellent verbal and written communication skills Strong problem-solving skills Eagerness to learn new techniques Preferred Experience working with small molecule or large molecule synthetic targets either in an academic or industrial setting Basic familiarity with GLP/GMP regulations Experience with small-molecule or macromolecule analytical techniques (e.g., HPLC, UV-Vis spectrophotometry, mass spectrometry, NMR, etc.) Wisconsin pay range $80,000-$90,000 USD Arrowhead provides competitive salaries and an excellent benefit package. All applicants must have authorization to work in the US for a company. California Applicant Privacy Policy

Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing. Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates. Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need. The Position The Associate Scientist III works in the Chemistry, Manufacturing, and Controls Group focusing on oligonucleotide synthesis development. This is an ideal position for an individual with an organic chemistry background who has an interest in projects related to novel technology in synthesis and purification of oligonucleotides and bioconjugates. Responsibilities Work independently or with senior scientists to develop new synthetic approaches to desired compounds while keeping an eye toward large-scale synthesis Perform solid-phase synthesis and purification of oligonucleotide drug candidates Mentor others on internal protocols, practices and processes Analyze small-molecule and macromolecular targets using standard methods Recognize unusual circumstances, identify root cause(s) to problems, and begins providing recommendations to new approaches, techniques and/or practices Maintain a well-documented laboratory notebook Cerate an action plan with project deliverables with high-level guidance Track progress against project timelines, generate regular status updates, and communicate progress and issues to management, including presentation of findings at team meetings Independently coordinate delivery of materials both internally and externally Requirements MS in Chemistry or related field (minimum 2 years of relevant laboratory experience) or BS in Chemistry with 5+ years of experience Experience with synthetic organic chemistry Excellent verbal and written communication skills Strong problem-solving skills Eagerness to learn new techniques Preferred Experience working with small molecule or large molecule synthetic targets either in an academic or industrial setting Basic familiarity with GLP/GMP regulations Experience with small-molecule or macromolecule analytical techniques (e.g., HPLC, UV-Vis spectrophotometry, mass spectrometry, NMR, etc.) Wisconsin pay range $80,000-$90,000 USD Arrowhead provides competitive salaries and an excellent benefit package. All applicants must have authorization to work in the US for a company. California Applicant Privacy Policy

The Associate Scientist III works in the Chemistry, Manufacturing, and Controls Group focusing on oligonucleotide synthesis development. This is an ideal position for an individual with an organic chemistry background who has an interest in projects related to novel technology in synthesis and purification of oligonucleotides and bioconjugates. Responsibilities * Work independently or with senior scientists to develop new synthetic approaches to desired compounds while keeping an eye toward large-scale synthesis * Perform solid-phase synthesis and purification of oligonucleotide drug candidates * Mentor others on internal protocols, practices and processes * Analyze small-molecule and macromolecular targets using standard methods * Recognize unusual circumstances, identify root cause(s) to problems, and begins providing recommendations to new approaches, techniques and/or practices * Maintain a well-documented laboratory notebook * Cerate an action plan with project deliverables with high-level guidance * Track progress against project timelines, generate regular status updates, and communicate progress and issues to management, including presentation of findings at team meetings * Independently coordinate delivery of materials both internally and externally Requirements * MS in Chemistry or related field (minimum 2 years of relevant laboratory experience) or BS in Chemistry with 5+ years of experience * Experience with synthetic organic chemistry * Excellent verbal and written communication skills * Strong problem-solving skills * Eagerness to learn new techniques Preferred * Experience working with small molecule or large molecule synthetic targets either in an academic or industrial setting * Basic familiarity with GLP/GMP regulations * Experience with small-molecule or macromolecule analytical techniques (e.g., HPLC, UV-Vis spectrophotometry, mass spectrometry, NMR, etc.)

Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing. Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates. Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need. The Position This position will involve assisting in the synthesis and subsequent purification steps of large scale oligonucleotides. The operator must comply with GLP/GMP protocols and be able to follow all association SOPs and work instructions when performing and documenting operations. Responsibilities Prepare and follow batch records, SOPs, and work instructions to detail Document all operations in batch records and logbooks Able to identify, design, and implement process improvements Comply with GMP protocols Operate large scale oligonucleotide manufacturing equipment (i.e. oligonucleotide synthesizer, purification skid, tangential flow filtration system, lyophilizer, ChemGlass reactors, pH/conductivity meters, peristaltic pumps, etc.) Assist other chemists within the Manufacturing group during synthesis and purification of oligonucleotides including: Reagent solution preparation Mobile phase preparation Column Packing Fraction collection Perform oligonucleotide/intermediate analysis via LCMS Assist in scale up/process development from small/mid-scale chemistry Communicate with cross-functional groups such as Process Development, Analytical Development, Quality Control, Quality Assurance, etc. Maintain a clean work space Maintain safety by wearing required personal protective equipment Track and update raw material usage in D365 ERP software Act as production campaign lead Assist with new personnel training Address and resolve production challenges proactively, utilizing analytical and critical thinking skills Requirements: Bachelor's degree in a scientific field 5-10 years experience in a similar position Good verbal and written communication skills Ability to work in a team environment Ability to pay attention to detail Preferred: Experience working in a GMP setting and controlled documentation Wisconsin pay range $85,000-$95,000 USD Arrowhead provides competitive salaries and an excellent benefit package. All applicants must have authorization to work in the US for a company. California Applicant Privacy Policy

Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing. Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates. Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need. The Position The Associate Manufacturing Scientist I (third shift) supports the production of drug substances and drug products. Their responsibility will focus on the preparation of solutions and reagents by following standard protocols. This technically focused position supports lab work, helps solve problems, and effectively communicates with colleagues. 3rd shift work hours are 10 pm - 8:30 am and includes a 15% shift differential. Responsibilities Follow batch records, SOPs, and work instructions to detail Document all operations in batch records and notebooks Comply with GMP protocols Assist other chemists within the CMC group during synthesis and chromatography of oligonucleotides including: Reagent solution preparation Column Packing Mobile phase preparation Fraction collection Operate TFF to desalt purified RNA solutions Operate a lyophilizer and package solid drug substance Execute processes as part of a team to ensure production timelines are kept and quality product is produced Maintain a clean work space Maintain safety by wearing required personal protective equipment Requirements BS or MS in chemistry, biochemistry, engineering, or related scientific field Entry level to 3 years experience in a similar position Good verbal and written communication skills Ability to work in a team environment Ability to pay attention to detail Preferred Experience working in a GMP setting with controlled documentation Wisconsin pay range $63,000-$73,000 USD Arrowhead provides competitive salaries and an excellent benefit package. All applicants must have authorization to work in the US for a company. California Applicant Privacy Policy

Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing. Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates. Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need. The Position The Associate Manufacturing Scientist I (second shift) will assist in the synthesis and subsequent purification steps of large scale oligonucleotides. The operator must comply with GLP/GMP protocols and be able to follow all association SOPs and work instructions when performing and documenting operations. 2 nd shift work hours are 1pm - 11:30pm and includes a 10% shift differential. Responsibilities Follow batch records, SOPs, and work instructions to detail Document all operations in batch records and notebooks Comply with GMP protocols Assist other chemists within the CMC group during synthesis and chromatography of oligonucleotides including: Reagent solution preparation Column Packing Mobile phase preparation Fraction collection Operate TFF to desalt purified RNA solutions Operate a lyophilizer and package solid drug substance Execute processes as part of a team to ensure production timelines are kept and quality product is produced Maintain a clean work space Maintain safety by wearing required personal protective equipment Requirements: Bachelor's degree in chemistry, biochemistry, engineering, or related scientific field Experience working in a GMP setting and controlled documentation Good verbal and written communication skills Ability to work in a team environment Ability to pay attention to detail Wisconsin pay range $63,000-$73,000 USD Arrowhead provides competitive salaries and an excellent benefit package. All applicants must have authorization to work in the US for a company. California Applicant Privacy Policy

Site: The Brigham and Women's Hospital, Inc. Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. We're offering a generous sign-on bonus of $10,000 to eligible candidates who join our team. Recognizing and valuing exceptional talent, we're excited to discuss the details of this bonus during the interview process. Job Summary Summary As required by CLIA, testing personnel are responsible for specimen processing, test performance, and reporting test results. Each individual performs only those tests authorized by the laboratory director and requiring a level of skill appropriate to their education, training, experience, and technical abilities. The role requires working independently in an efficient and organized manner to ensure accurate results and documentation. This position requires professional-level knowledge to accurately read and interpret test results used by providers in diagnosing and treating diseases. The Medical Laboratory Scientist, Senior I, in their role as Technical Supervisor, Technical Consultant, or General Supervisor as defined by CLIA, may be delegated responsibility for technical oversight of the laboratory, including day-to-day supervision of operations and personnel performing testing and reporting results. Under the general supervision of the Technical Director and Clinical Supervisors, the Senior Technologist I also oversees assigned workstations, including Quality Control (QC) review, staff training, competency assessments, and inventory management. Does this position require patient care? No Essential Functions After successful completion of orientation, training, and competency assessment on all applicable instruments and methods, the Senior Technologist I must: Follow the laboratory's procedures for specimen handling and processing, test analyses, reporting, and recordkeeping. Maintain records demonstrating that proficiency testing samples are analyzed in the same manner as patient samples. Adhere to quality control policies and document all QC activities, calibrations, and maintenance. Follow established corrective action procedures when test systems fall outside acceptable performance standards. Identify issues that may adversely affect test performance or result reporting, and either correct them or immediately notify the appropriate supervisor or director. Document all corrective actions taken when test systems deviate from established performance specifications, in accordance with 42 CFR 493.1425 and 493.1495. Qualifications Education Bachelor's Degree Clinical Laboratory Sciences required or Bachelor's Degree Medical Technology required or Bachelor's Degree Laboratory Sciences required and Can this role accept experience in lieu of a degree? No Licenses and Credentials Medical Technologist (ASCP) [MLT, MT, MLA, Histologists] - American Society for Clinical Pathology Board of Certification (ASCP-BOC) required Experience lab experience 4 years required Knowledge, Skills and Abilities * The knowledge, both practical and theoretical, of tests and procedures necessary to review findings and advise and direct subordinates in action. * Demonstrates advanced level of analytical skills and judgement. * Must have understanding of computer technology and its application to analytical procedures and quality control. * Must have a comprehensive understanding of laboratory equipment and its operation, maintenance, and repair, and analytic techniques. * Must have the ability to work independently, evaluate situations and act appropriately. * Ability to multitask in a fast-paced environment. * Must have the ability to pay careful attention to detail and to adhere to written protocols, including communication with supervisors when issues are identified. * Must be able to perform as a team member. * Excellent interpersonal skills. * Ability to interact professionally and effectively with numerous staff including physicians, hospital personnel, employees, and patients. * Advanced knowledge of federal, state and accreditation requirements. Additional Job Details (if applicable) Physical RequirementsStanding Frequently (34-66%) Walking Frequently (34-66%) Sitting Occasionally (3-33%) Lifting Frequently (34-66%) 35lbs+ (w/assisted device) Carrying Frequently (34-66%) 20lbs - 35lbs Pushing Occasionally (3-33%) Pulling Occasionally (3-33%) Climbing Rarely (Less than 2%) Balancing Frequently (34-66%) Stooping Occasionally (3-33%) Kneeling Occasionally (3-33%) Crouching Occasionally (3-33%) Crawling Rarely (Less than 2%) Reaching Frequently (34-66%) Gross Manipulation (Handling) Frequently (34-66%) Fine Manipulation (Fingering) Frequently (34-66%) Feeling Constantly (67-100%) Foot Use Rarely (Less than 2%) Vision - Far Constantly (67-100%) Vision - Near Constantly (67-100%) Talking Constantly (67-100%) Hearing Constantly (67-100%) Remote Type Onsite Work Location 221 Longwood Avenue Scheduled Weekly Hours 40 Employee Type Regular Work Shift Day (United States of America) Pay Range $33.46 - $48.66/Hourly Grade 7 At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package. EEO Statement: The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at **************. Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership "looks like" by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.

Site: The Brigham and Women's Hospital, Inc. Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. We're offering a generous sign-on bonus of $10,000 to eligible candidates who join our team. Recognizing and valuing exceptional talent, we're excited to discuss the details of this bonus during the interview process. Job Summary Summary As required by CLIA, testing personnel are responsible for specimen processing, test performance, and reporting test results. Each individual performs only those tests authorized by the laboratory director and requiring a level of skill appropriate to their education, training, experience, and technical abilities. The role requires working independently in an efficient and organized manner to ensure accurate results and documentation. This position requires professional-level knowledge to accurately read and interpret test results used by providers in diagnosing and treating diseases. The Medical Laboratory Scientist, Senior I, in their role as Technical Supervisor, Technical Consultant, or General Supervisor as defined by CLIA, may be delegated responsibility for technical oversight of the laboratory, including day-to-day supervision of operations and personnel performing testing and reporting results. Under the general supervision of the Technical Director and Clinical Supervisors, the Senior Technologist I also oversees assigned workstations, including Quality Control (QC) review, staff training, competency assessments, and inventory management. Does this position require patient care? No Essential Functions After successful completion of orientation, training, and competency assessment on all applicable instruments and methods, the Senior Technologist I must: Follow the laboratory's procedures for specimen handling and processing, test analyses, reporting, and recordkeeping. Maintain records demonstrating that proficiency testing samples are analyzed in the same manner as patient samples. Adhere to quality control policies and document all QC activities, calibrations, and maintenance. Follow established corrective action procedures when test systems fall outside acceptable performance standards. Identify issues that may adversely affect test performance or result reporting, and either correct them or immediately notify the appropriate supervisor or director. Document all corrective actions taken when test systems deviate from established performance specifications, in accordance with 42 CFR 493.1425 and 493.1495. Qualifications Education Bachelor's Degree Clinical Laboratory Sciences required or Bachelor's Degree Medical Technology required or Bachelor's Degree Laboratory Sciences required and Can this role accept experience in lieu of a degree? No Licenses and Credentials Medical Technologist (ASCP) [MLT, MT, MLA, Histologists] - American Society for Clinical Pathology Board of Certification (ASCP-BOC) required Experience lab experience 4 years required Knowledge, Skills and Abilities - The knowledge, both practical and theoretical, of tests and procedures necessary to review findings and advise and direct subordinates in action. - Demonstrates advanced level of analytical skills and judgement. - Must have understanding of computer technology and its application to analytical procedures and quality control. - Must have a comprehensive understanding of laboratory equipment and its operation, maintenance, and repair, and analytic techniques. - Must have the ability to work independently, evaluate situations and act appropriately. - Ability to multitask in a fast-paced environment. - Must have the ability to pay careful attention to detail and to adhere to written protocols, including communication with supervisors when issues are identified. - Must be able to perform as a team member. - Excellent interpersonal skills. - Ability to interact professionally and effectively with numerous staff including physicians, hospital personnel, employees, and patients. - Advanced knowledge of federal, state and accreditation requirements. Additional Job Details (if applicable) Physical Requirements Standing Frequently (34-66%) Walking Frequently (34-66%) Sitting Occasionally (3-33%) Lifting Frequently (34-66%) 35lbs+ (w/assisted device) Carrying Frequently (34-66%) 20lbs - 35lbs Pushing Occasionally (3-33%) Pulling Occasionally (3-33%) Climbing Rarely (Less than 2%) Balancing Frequently (34-66%) Stooping Occasionally (3-33%) Kneeling Occasionally (3-33%) Crouching Occasionally (3-33%) Crawling Rarely (Less than 2%) Reaching Frequently (34-66%) Gross Manipulation (Handling) Frequently (34-66%) Fine Manipulation (Fingering) Frequently (34-66%) Feeling Constantly (67-100%) Foot Use Rarely (Less than 2%) Vision - Far Constantly (67-100%) Vision - Near Constantly (67-100%) Talking Constantly (67-100%) Hearing Constantly (67-100%) Remote Type Onsite Work Location 221 Longwood Avenue Scheduled Weekly Hours 40 Employee Type Regular Work Shift Day (United States of America) Pay Range $33.46 - $48.66/Hourly Grade 7 At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package. EEO Statement: The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at **************. Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.

Job Description Enjoy what you do while contributing to a company that makes a difference in people's lives. Shady Grove Fertility, one of the premier fertility centers in the United States, seeks experienced, compassionate, and dynamic team players who are committed to delivering exceptional patient care to join our growing practice. The work we do building families offers stimulation, challenge, and personal reward. Sign on Bonus of 10K! We have an immediate opening for a full-time Senior Embryologist to join our team in Chesterbrook, Pennsylvania. The schedule is working Monday through Friday from 7:30 AM to 4:00 PM with rotating weekends, holiday rotation. Approximately 1 weekend/month. How You'll Contribute: We always do whatever it takes, even if it isn't specifically our “job.” In general, the Senior Embryologist is responsible for: Identification, assessment and culture of oocytes; sperm preparation and insemination of oocytes (conventional insemination and ICSI) Assessment and selection embryos for transfer; embryo vitrification, warming and storage Oocyte vitrification, warming and storage Preparation and care of gametes/embryos throughout the laboratory process: IVF, ICSI, VIT, ET, Warming and Embryo Biopsy Vitrification and warming of embryos at varying stages of development Assessing fertilization and zygote quality following insemination Familiarity with data entry into an EMR Familiarity with MESA, PESA, TESA and TESE collection Experience with regulatory guidelines and inspections (e.g. CLIA, FDA, TJC, CAP) What You'll Bring: The skills and education we need are: Minimum 5 years experience in Embryology. Must have a Bachelor's degree or higher in a relevant laboratory science field Must demonstrate the ability to function effectively without direct supervision, and to perform laboratory services in accordance with the Laboratory Philosophy and Operating Standards. Proven ability to access, input, and retrieve information from a computer. Knowledge of office procedures and office machines (i.e. computer, fax, copier, etc.). Ability to work as part of a multidisciplinary team. Ability to work in a high standard, stressful environment. Ability to communicate accurately and concisely. Ability to develop interpersonal working relationships with colleagues Must be authorized to work in the U.S.A. More important than the best skills, however, is the right person. Employees who embrace our mission, vision, and core values are highly successful. What We Offer: We are proud to provide a comprehensive and competitive benefits package tailored to support the needs of our team members across all employment types: Full-Time Employees (30+ hours/week): Medical, dental, and vision insurance, 401(k) with company match, tuition assistance, performance-based bonus opportunities, generous paid time off, and paid holidays Part-Time Employees: 401(k) with company match and performance-based bonus opportunities Per Diem Employees: 401(k) with company match At Shady Grove Fertility, we promote and develop individual strengths in order to help staff grow personally and professionally. Our core values - Empathy, Patient Focus, Integrity, Commitment, and Compassion (EPICC) - guide us daily to work hard and enjoy what we do. We're committed to growing our practice and are always looking to promote from within. This is an ideal time to join our team! To learn more about our company and culture, visit here.

**Penn State Health** - **Hershey Medical Center** **Work Type:** Full Time **FTE:** 1.00 **Shift:** Day **Hours:** Variable **Recruiter Contact:** Corey Cunningham at ************************************ (//************************************) **SUMMARY OF POSITION:** Work with aspects of in-vitro fertilization (IVF) treatment and other programs of assisted reproduction. This includes working with human or animal gametes i.e. sperm, eggs and embryos. Duties include; oocyte retrieval, semen preparations, fertilization, monitoring of embryo development, cryopreservation, and micromanipulation procedures for ICSI and assisted hatching. **MINIMUM QUALIFICATIONS** : + Bachelor's degree in biology, zoology, biochemistry or other related scientific field plus three years of clinical/research experience in a cell culture Laboratory required. + Three (3) years relevant experience. **PREFERRED QUALIFICATIONS** + Experience in an In Vitro Fertilization laboratory preferred. + Micromanipulation experience preferred. **WHY PENN STATE HEALTH?** Penn State Health offers exceptional opportunities to learn and grow, exposure to a wide patient population, and the ability to provide individualized, innovative, and specialized care to patients in the community. **Penn State Health offers an exceptional benefits package including medical, dental and vision with no waiting period as well as a Total Rewards Program that highlights a few of the many additional offerings below:** + **_Be Well_** with Employee Wellness Programs, and Fitness Discounts (University Fitness Center, Peloton). + **_Be Balanced_** with Generous Paid Time Off, Personal Time, and Paid Parental Leave. + **_Be Secured_** with Retirement, Extended Illness Bank, Life Insurance, and Identity Theft Protection. + **_Be Rewarded_** with Competitive Pay, Tuition Reimbursement, and PAWS UP employee recognition program. + **_Be Supported_** by the HR Solution Center, Learning and Organizational Development and Virtual Benefits Orientation, Employee Exclusive Concierge Service for scheduling. **WHY PENN STATE HEALTH MILTON HERSHEY MEDICAL CENTER?** Penn State Hershey Medical Center is Central Pennsylvania's only Academic Medical Center, Level 1 Regional Adult and Pediatric Trauma Center, and Tertiary Care Provider. As a four-time Magnet-designated hospital, Hershey Medical Center values the hard work and dedication that our employees exhibit every day. Through our core values of Respect, Integrity, Teamwork, and Excellence, our employees are a team committed to compassionate care for our diverse patient population, our community and each other. As a valued team member, we promote continued professional development, specialty certification, continuing education, and career growth. **YOU TAKE CARE OF THEM. WE'LL TAKE CARE OF YOU. State-of-the-art equipment, endless learning, and a culture of excellence - that's Penn State Health. But what makes our healthcare award-winning? That's all you.** _This job posting is a general outline of duties performed and is not to be misconstrued as encompassing all duties performed within the position. Eligibility for shift differential pay based on the terms outlined in company policy or union contract._ _All individuals (including current employees) selected for a position will undergo a background check appropriate for the position's responsibilities._ _Penn State Health is an Equal Opportunity Employer and does not discriminate on the basis of any protected class including disability or veteran status. Penn State Health's policies and objectives are in direct compliance with all federal and state constitutional provisions, laws, regulations, guidelines, and executive orders that prohibit or outlaw discrimination._ **Union:** Non Bargained IND 123 \#LI-TB1 **Position** Embryologist - Reproductive Endocrinology **Location** US:PA: Hershey | Therapy Services | Full Time **Req ID** 77602

Embryologist III reports to the laboratory director and follows corporate policies/procedures and departmental policies/procedures approved by the laboratory director. Embryologist III is responsible, along with other Lab staff, for providing quality Embryology procedures including but not limited to intracytoplasmic sperm injection (ICSI), Assisted hatching (AH), embryo grading and transfer, embryo/blastocyst vitrification, blastocyst biopsy, biopsied cell processing, oocyte vitrification and warming for infertile couples wishing to achieve pregnancy. Responsibilities include technical benchwork, administrative tasks as assigned by the lab director, quality control and quality assurance activities and documentation including result reporting and tissue transmittal (paper as well as electronic). Participates in on call rotation for alarm handling.Embryologist III reports to the laboratory director and follows corporate policies/procedures and departmental policies/procedures approved by the laboratory director. Embryologist III is responsible, along with other Lab staff, for providing quality Embryology procedures including but not limited to intracytoplasmic sperm injection (ICSI), Assisted hatching (AH), embryo grading and transfer, embryo/blastocyst vitrification, blastocyst biopsy, biopsied cell processing, oocyte vitrification and warming for infertile couples wishing to achieve pregnancy. Responsibilities include technical benchwork, administrative tasks as assigned by the lab director, quality control and quality assurance activities and documentation including result reporting and tissue transmittal (paper as well as electronic). Participates in on call rotation for alarm handling. Essential Job Functions- Expert Level Interacts with patients and staff professionally. Maintains patient confidentiality. Learns elements of patient correspondence for the disposition of their cryo stored samples. Maintains good working relationships and helps create a patient centered service environment. Communicates with other departments of Island Fertility and communicates lab information with Physicians as appropriate. This includes following proper hierarchy protocol. Performs data entry into LIS/EMR and SART. Complete assigned competencies within deadline. Follows safety policies. Maintain a safe working environment. Reports promptly with utmost truth and transparency, any nonconformance/incident/deviation from standard operating procedure(s) whether involved in, discovered, or observed. Complete assigned training and competencies within deadline. Trains new hires per laboratory director's request.