Doctoral Fellow jobs at Genentech - 83 jobs

Postdoctoral Fellow, Computational Biology & Medicine/Neuroscience
Genentech 4.5
Doctoral fellow job at Genentech
** We advance science so that we all have more time with the people we love. A position is available for a postdoctoral fellow to join the Computational Sciences -Center of Excellence (CS-CoE) organization which uses data, by developing best in class computational methods, and applying them to the most relevant scientific problems across all stages of the pipeline. This position is based within the Pandey Lab in Computational Biology and Medicine/Neuroscience. The postdoctoral position is focused on applying cutting edge computational methods to understand stromal cells of the brain particularly their pathological role in neuroinflammatory diseases. Spanning single cell transcriptomics, genetics, proteomics, spatial transcriptomics and functional genomics, the postdoctoral fellow will lead large scale integrative analyses to delineate the complex and overlooked role that stromal cells might play in disease pathogenesis. While this position is computational, the project is highly collaborative, involving regular interaction with laboratory colleagues in Neuroscience and Translational Medicine. The Opportunity: + Opportunity to work closely with computational colleagues to apply cutting edge computation to impactful scientific problems in neuroscience + Leverage multimodal high dimensional data - including single cell and spatial transcriptomics, proteomics and genetics - to investigate the role of stromal cells in neuroinflammation and neurodegeneration. + Exploratory research in a fast-paced setting with the potential for real impact on patients + Technical and scientific mentorship from computational and laboratory colleagues in the development and testing of biological hypotheses + Present at external scientific conferences and publish scientific insights in high-impact journals Who You Are: + Ph.D. in Computational Biology, Bioinformatics, Neuroscience or related field + Experience with bulk and/or single-cell omics data analysis (e.g. bulk genomics, transcriptomics, proteomics, single-cell RNA-seq, Perturb-seq, spatial transcriptomics ) + Proven ability to bridge bioinformatics and genetics to solve complex problems, ideally within CNS health or disease + Demonstrated ability to clearly and effectively communicate complex computational findings to both technical and non-technical audiences; this should be in written and verbal form, as evidenced by first-author publications in high-impact journals and presentations at scientific conferences. + Independent, highly motivated, and highly collaborative with the ability to work together with multi-disciplinary teams of computational and laboratory biologists Preferred Qualifications: + Passionate about working in a scientific environment, especially one that is related to drug discovery and development + Collaborative mindset and enthusiasm for bridging computation with functional biology. + Quick learner, are curious about new areas and the opportunity to build expertise, and courageously boldly and creatively take initiative to see your ideas implemented + Able to perform at a high level in a fast changing and demanding environment The expected salary range for this position based on the primary location of California is $110,000 to $120,000 . Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed at the link provided below. Benefits (**************************************************** Relocation benefits are available for this job posting. About Genentech's Postdoctoral Program: Elevate your research career to new heights with Genetech's Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions. The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader. The Genentech Postdoc Program (************************************************ provides access to world-class seminars, professional development workshops, and networking opportunities. Apply now to Genentech's Postdoctoral Program and unlock your full potential! \#LI-PL1 \#postdoc Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants (***************************************************************************************************** .
$110k-120k yearly 5d ago

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Postdoctoral Fellow- Biological Chemistry, Kirchhofer lab
Genentech 4.5
Doctoral fellow job at Genentech
A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Genentech. The Opportunity We are seeking a highly motivated postdoctoral fellow to join the laboratory of Dr. Daniel Kirchhofer in the Department of Biological Chemistry at Genentech. This position offers an exciting opportunity to use state-of-the-art peptide display technologies - including phage and mRNA display of macrocyclic and cystine-knot peptide libraries - to discover peptides that modulate the function of therapeutically relevant protein targets. A major focus will be on members of the type II transmembrane serine protease family, cell-surface enzymes implicated in disease processes such as viral entry. In parallel, you will engineer disulfide-constrained peptide libraries designed to engage challenging, flat protein-protein interfaces, using a newly developed scaffold with a unique surface topology, and will leverage machine-learning-assisted methods for peptide sequence optimization. To elucidate mechanisms of peptide activity, the successful candidate will apply a broad range of biochemical, biophysical, structural, and cellular methods. The ideal applicant is an independent, creative scientist who thrives in a collaborative, team-oriented environment. The position offers extensive opportunities to interact with the vibrant Genentech postdoctoral community as well as scientists across multiple departments. Who You Are: A Ph.D. in biochemistry, biophysics, structural biology or related discipline and a proven record of productivity in their graduate career as demonstrated by first-author publications. Preferred Qualifications: * Strong experience in molecular biology * Expertise in engineering, expressing and purifying proteins * Experience with directed evolution (yeast, phage, mRNA display, etc.) is preferred * Experience in peptide chemistry is a plus * Proficiency in surface plasmon resonance or biolayer interferometry * Proficient in structural biology (crystallography and or cryo-EM) is a plus * Experience with tissue culture, cell-based assays * Strong analytical, collaborative, communication and organizational skills For information about the Kirchhofer Lab at Genentech, please go to: **************************************************************** Postdoc Program Elevate your research career to new heights with Genentech's Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions. The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader. The Genentech Postdoc Program provides access to world-class seminars, professional development workshops, and networking opportunities. Apply now to Genentech Postdoctoral Program and unlock your full potential! The expected salary range for this position based on the primary location of California is $100,000 to $106,500 . Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed at the link provided below. Benefits Relocation benefits are available for this job posting. #LI-PL1 #postdoc Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
$100k-106.5k yearly 12d ago
Senior Oncology Bioinformatics Scientist
Gilead Sciences, Inc. 4.5
Foster City, CA jobs
A leading biotech company in Foster City is searching for a Senior Scientist with extensive experience in analyzing omics data such as RNA-Seq and WES. The ideal candidate will have a PhD and 8+ years of experience in the pharmaceutical or biotech industry, strong statistics knowledge, and excellent communication skills. Responsibilities include synthesizing scientific questions into research efforts and empowering teams to achieve organizational objectives. Join a dynamic team that values diversity and supports professional growth. #J-18808-Ljbffr
$88k-133k yearly est. 5d ago
Lead Target Discovery Scientist - In Vitro Biology
Amgen Sa 4.8
Thousand Oaks, CA jobs
A leading biotech company in Thousand Oaks seeks a Senior Principal Scientist to lead a team focused on in vitro modeling for target discovery. This role involves collaboration across therapeutic areas and implementing innovative technologies. Candidates should have a doctorate and extensive experience in a related field. Competitive compensation, flexible work models, and a comprehensive benefits package are offered. #J-18808-Ljbffr
$125k-173k yearly est. 2d ago
Postdoctoral Fellow, Computational Biology & Medicine/Neuroscience
Genentech 4.5
Doctoral fellow job at Genentech
We advance science so that we all have more time with the people we love. A position is available for a postdoctoral fellow to join the Computational Sciences -Center of Excellence (CS-CoE) organization which uses data, by developing best in class computational methods, and applying them to the most relevant scientific problems across all stages of the pipeline. This position is based within the Pandey Lab in Computational Biology and Medicine/Neuroscience. The postdoctoral position is focused on applying cutting edge computational methods to understand stromal cells of the brain particularly their pathological role in neuroinflammatory diseases. Spanning single cell transcriptomics, genetics, proteomics, spatial transcriptomics and functional genomics, the postdoctoral fellow will lead large scale integrative analyses to delineate the complex and overlooked role that stromal cells might play in disease pathogenesis. While this position is computational, the project is highly collaborative, involving regular interaction with laboratory colleagues in Neuroscience and Translational Medicine. The Opportunity: Opportunity to work closely with computational colleagues to apply cutting edge computation to impactful scientific problems in neuroscience Leverage multimodal high dimensional data - including single cell and spatial transcriptomics, proteomics and genetics - to investigate the role of stromal cells in neuroinflammation and neurodegeneration. Exploratory research in a fast-paced setting with the potential for real impact on patients Technical and scientific mentorship from computational and laboratory colleagues in the development and testing of biological hypotheses Present at external scientific conferences and publish scientific insights in high-impact journals Who You Are: Ph.D. in Computational Biology, Bioinformatics, Neuroscience or related field Experience with bulk and/or single-cell omics data analysis (e.g. bulk genomics, transcriptomics, proteomics, single-cell RNA-seq, Perturb-seq, spatial transcriptomics ) Proven ability to bridge bioinformatics and genetics to solve complex problems, ideally within CNS health or disease Demonstrated ability to clearly and effectively communicate complex computational findings to both technical and non-technical audiences; this should be in written and verbal form, as evidenced by first-author publications in high-impact journals and presentations at scientific conferences. Independent, highly motivated, and highly collaborative with the ability to work together with multi-disciplinary teams of computational and laboratory biologists Preferred Qualifications: Passionate about working in a scientific environment, especially one that is related to drug discovery and development Collaborative mindset and enthusiasm for bridging computation with functional biology. Quick learner, are curious about new areas and the opportunity to build expertise, and courageously boldly and creatively take initiative to see your ideas implemented Able to perform at a high level in a fast changing and demanding environment The expected salary range for this position based on the primary location of California is $110,000 to $120,000 . Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed at the link provided below. Benefits Relocation benefits are available for this job posting. About Genentech's Postdoctoral Program: Elevate your research career to new heights with Genetech's Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions. The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader. The Genentech Postdoc Program provides access to world-class seminars, professional development workshops, and networking opportunities. Apply now to Genentech's Postdoctoral Program and unlock your full potential! #LI-PL1 #postdoc Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
$110k-120k yearly Auto-Apply 6d ago
Postdoctoral Fellow - Cell Culture and Bioprocess Operations, Park Lab
Genentech 4.5
Doctoral fellow job at Genentech
A Postdoctoral Fellow position is available for a highly motivated and independent candidate to join the laboratory of Dr. Jonathan Park in the Research Materials Group (RMG) within the Cell Culture and Bioprocess Operations (CCBO) department at Genentech. RMG supports Research & Development efforts across the company by performing transient transfections to produce recombinant proteins. This position will focus on developing a novel, high-titer Chinese Hamster Ovary (CHO) transient expression platform. The project aims to understand and overcome the biological bottlenecks of transient gene expression (TGE) in CHO cells, such as limiting factors like nuclear DNA uptake, cell cycle progression, and transcriptional activity, which restrict current protein yields. You will utilize advanced molecular and genetic engineering approaches, including OMICS, CRISPR/Cas9, and other advanced molecular biology tools, to identify and overcome intracellular barriers to plasmid delivery and expression. You will explore ways to improve protein expression, including screening genome-wide libraries for increased expression, with the ultimate goal of optimizing a cell line for a high-throughput transient transfection process. The Opportunity: * You will have opportunities to productively collaborate with other researchers across gRED (Genentech Research and Early Development) and PTD (Pharmaceutical Technical Development), present your work to project teams, and contribute to scientific publications. * As a member of the RMG and CCBO, you will gain exposure to the pipeline from early Drug Discovery to Development, contributing to the reduction of cycle times for lead molecule identification. * You will be part of the Genentech post-doctoral training program that provides an outstanding environment and the opportunity to pursue fundamental basic science questions in an environment focused on drug development and breakthrough discoveries. Who You Are: * Ph.D. with a proven track record of excellence in Chemical Engineering, Bioengineering, Molecular Biology, Cell Biology, or a related field. * Must have advanced at least one key research project as evidenced by a first-author paper published or accepted in a leading peer-reviewed journal. * Independent scientist with outstanding communication skills, a strong passion and commitment to science and bioprocess innovation, who works well within a team. * Excited about applying genetic and molecular engineering to solve complex challenges in protein production. Preferred Qualifications: * Hands-on experience with mammalian cell culture (specifically CHO cells) and transient expression systems is highly desired. * Experience with molecular biology techniques, including vector design, cloning, and genetic engineering (e.g., CRISPR/Cas9, transposon-mediated systems). * Working knowledge of transfection methods or engineered transcription/translation systems is a plus. * Familiarity with high-throughput screening or automated liquid handling systems is advantageous. The expected salary range for this position based on the primary location of South San Francisco California is $100,000 to $106,500. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed at the link provided below. Benefits Relocation benefits are available for this job posting. Postdoc Program Elevate your research career to new heights with Genetech's Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions. The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader. The Genentech Postdoc Program provides access to world-class seminars, professional development workshops, and networking opportunities. Apply now to Genentech Postdoctoral Program and unlock your full potential! #LI-PL1 #postdoc Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
$100k-106.5k yearly 6d ago
Postdoctoral Fellow - Cell Culture and Bioprocess Operations, Park Lab
Genentech 4.5
Doctoral fellow job at Genentech
** A Postdoctoral Fellow position is available for a highly motivated and independent candidate to join the laboratory of Dr. Jonathan Park in the Research Materials Group (RMG) within the Cell Culture and Bioprocess Operations (CCBO) department at Genentech. RMG supports Research & Development efforts across the company by performing transient transfections to produce recombinant proteins. This position will focus on developing a novel, high-titer Chinese Hamster Ovary (CHO) transient expression platform. The project aims to understand and overcome the biological bottlenecks of transient gene expression (TGE) in CHO cells, such as limiting factors like nuclear DNA uptake, cell cycle progression, and transcriptional activity, which restrict current protein yields. You will utilize advanced molecular and genetic engineering approaches, including OMICS, CRISPR/Cas9, and other advanced molecular biology tools, to identify and overcome intracellular barriers to plasmid delivery and expression. You will explore ways to improve protein expression, including screening genome-wide libraries for increased expression, with the ultimate goal of optimizing a cell line for a high-throughput transient transfection process. **The Opportunity:** + You will have opportunities to productively collaborate with other researchers across gRED (Genentech Research and Early Development) and PTD (Pharmaceutical Technical Development), present your work to project teams, and contribute to scientific publications. + As a member of the RMG and CCBO, you will gain exposure to the pipeline from early Drug Discovery to Development, contributing to the reduction of cycle times for lead molecule identification. + You will be part of the Genentech post-doctoral training program that provides an outstanding environment and the opportunity to pursue fundamental basic science questions in an environment focused on drug development and breakthrough discoveries. **Who You Are:** + Ph.D. with a proven track record of excellence in Chemical Engineering, Bioengineering, Molecular Biology, Cell Biology, or a related field. + Must have advanced at least one key research project as evidenced by a first-author paper published or accepted in a leading peer-reviewed journal. + Independent scientist with outstanding communication skills, a strong passion and commitment to science and bioprocess innovation, who works well within a team. + Excited about applying genetic and molecular engineering to solve complex challenges in protein production. **Preferred Qualifications:** + Hands-on experience with mammalian cell culture (specifically CHO cells) and transient expression systems is highly desired. + Experience with molecular biology techniques, including vector design, cloning, and genetic engineering (e.g., CRISPR/Cas9, transposon-mediated systems). + Working knowledge of transfection methods or engineered transcription/translation systems is a plus. + Familiarity with high-throughput screening or automated liquid handling systems is advantageous. The expected salary range for this position based on the primary location of South San Francisco California is $100,000 to $106,500. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed at the link provided below. Benefits (**************************************************** Relocation benefits are available for this job posting. **Postdoc Program** Elevate your research career to new heights with Genetech's Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions. The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader. The Genentech Postdoc Program (************************************************ provides access to world-class seminars, professional development workshops, and networking opportunities. Apply now to Genentech Postdoctoral Program and unlock your full potential! \#LI-PL1 \#postdoc Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants (***************************************************************************************************** .
$100k-106.5k yearly 5d ago
Postdoctoral Fellow- Biological Chemistry, Kirchhofer lab
Genentech 4.5
Doctoral fellow job at Genentech
** A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Genentech. **The Opportunity** We are seeking a highly motivated postdoctoral fellow to join the laboratory of Dr. Daniel Kirchhofer in the Department of Biological Chemistry at Genentech. This position offers an exciting opportunity to use state-of-the-art peptide display technologies - including phage and mRNA display of macrocyclic and cystine-knot peptide libraries - to discover peptides that modulate the function of therapeutically relevant protein targets. A major focus will be on members of the type II transmembrane serine protease family, cell-surface enzymes implicated in disease processes such as viral entry. In parallel, you will engineer disulfide-constrained peptide libraries designed to engage challenging, flat protein-protein interfaces, using a newly developed scaffold with a unique surface topology, and will leverage machine-learning-assisted methods for peptide sequence optimization. To elucidate mechanisms of peptide activity, the successful candidate will apply a broad range of biochemical, biophysical, structural, and cellular methods. The ideal applicant is an independent, creative scientist who thrives in a collaborative, team-oriented environment. The position offers extensive opportunities to interact with the vibrant Genentech postdoctoral community as well as scientists across multiple departments. **Who You Are:** A Ph.D. in biochemistry, biophysics, structural biology or related discipline and a proven record of productivity in their graduate career as demonstrated by first-author publications. **Preferred Qualifications:** + Strong experience in molecular biology + Expertise in engineering, expressing and purifying proteins + Experience with directed evolution (yeast, phage, mRNA display, etc.) is preferred + Experience in peptide chemistry is a plus + Proficiency in surface plasmon resonance or biolayer interferometry + Proficient in structural biology (crystallography and or cryo-EM) is a plus + Experience with tissue culture, cell-based assays + Strong analytical, collaborative, communication and organizational skills For information about the Kirchhofer Lab at Genentech, please go to: **************************************************************** **Postdoc Program** Elevate your research career to new heights with Genentech's Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions. The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader. The Genentech Postdoc Program (************************************************ provides access to world-class seminars, professional development workshops, and networking opportunities. Apply now to Genentech Postdoctoral Program and unlock your full potential! The expected salary range for this position based on the primary location of California is $100,000 to $106,500 . Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed at the link provided below. Benefits (**************************************************** Relocation benefits are available for this job posting. \#LI-PL1 \#postdoc Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants (***************************************************************************************************** .
$100k-106.5k yearly 12d ago
Postdoctoral Fellow - Cell Culture and Bioprocess Operations, Park Lab
Genentech 4.5
Doctoral fellow job at Genentech
A Postdoctoral Fellow position is available for a highly motivated and independent candidate to join the laboratory of Dr. Jonathan Park in the Research Materials Group (RMG) within the Cell Culture and Bioprocess Operations (CCBO) department at Genentech. RMG supports Research & Development efforts across the company by performing transient transfections to produce recombinant proteins. This position will focus on developing a novel, high-titer Chinese Hamster Ovary (CHO) transient expression platform. The project aims to understand and overcome the biological bottlenecks of transient gene expression (TGE) in CHO cells, such as limiting factors like nuclear DNA uptake, cell cycle progression, and transcriptional activity, which restrict current protein yields. You will utilize advanced molecular and genetic engineering approaches, including OMICS, CRISPR/Cas9, and other advanced molecular biology tools, to identify and overcome intracellular barriers to plasmid delivery and expression. You will explore ways to improve protein expression, including screening genome-wide libraries for increased expression, with the ultimate goal of optimizing a cell line for a high-throughput transient transfection process. The Opportunity: You will have opportunities to productively collaborate with other researchers across gRED (Genentech Research and Early Development) and PTD (Pharmaceutical Technical Development), present your work to project teams, and contribute to scientific publications. As a member of the RMG and CCBO, you will gain exposure to the pipeline from early Drug Discovery to Development, contributing to the reduction of cycle times for lead molecule identification. You will be part of the Genentech post-doctoral training program that provides an outstanding environment and the opportunity to pursue fundamental basic science questions in an environment focused on drug development and breakthrough discoveries. Who You Are: Ph.D. with a proven track record of excellence in Chemical Engineering, Bioengineering, Molecular Biology, Cell Biology, or a related field. Must have advanced at least one key research project as evidenced by a first-author paper published or accepted in a leading peer-reviewed journal. Independent scientist with outstanding communication skills, a strong passion and commitment to science and bioprocess innovation, who works well within a team. Excited about applying genetic and molecular engineering to solve complex challenges in protein production. Preferred Qualifications: Hands-on experience with mammalian cell culture (specifically CHO cells) and transient expression systems is highly desired. Experience with molecular biology techniques, including vector design, cloning, and genetic engineering (e.g., CRISPR/Cas9, transposon-mediated systems). Working knowledge of transfection methods or engineered transcription/translation systems is a plus. Familiarity with high-throughput screening or automated liquid handling systems is advantageous. The expected salary range for this position based on the primary location of South San Francisco California is $100,000 to $106,500. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed at the link provided below. Benefits Relocation benefits are available for this job posting. Postdoc Program Elevate your research career to new heights with Genetech's Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions. The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader. The Genentech Postdoc Program provides access to world-class seminars, professional development workshops, and networking opportunities. Apply now to Genentech Postdoctoral Program and unlock your full potential! #LI-PL1 #postdoc Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
$100k-106.5k yearly Auto-Apply 7d ago
Postdoctoral Fellow - Translational Medicine, Johnston Lab
Genentech 4.5
Doctoral fellow job at Genentech
A healthier future. It's what drives us to innovate-to continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Genentech. A postdoctoral research fellow position is available in the laboratory of Dr. Robert Johnston within Translational Medicine Oncology at Genentech. Our laboratory is dedicated to conducting translational research in lung cancer, focusing on mechanisms of response and resistance to treatment, patient biomarkers and subsets, and tumor-host interactions. We utilize a deep collection of patient samples and clinical data and state-of-the-art omics techniques and preclinical models to generate new insights into disease biology and emerging therapies. The Opportunity: To lead an independent, end-to-end translational research program investigating immune fitness - the functional capacity of circulating immune cells - as a determinant and biomarker of response to immune checkpoint inhibitor (CPI) therapy in non-small cell lung cancer (NSCLC). To leverage large, clinically annotated NSCLC trial cohorts and state-of-the-art omics technologies. To collaborate widely and cross-functionally with colleagues at Genentech, including molecule development teams. To participate in Genentech's postdoctoral training program, which offers outstanding training and mentorship, opportunities to present work internally and externally, career development support, and exposure to an environment focused on drug development and breakthrough discoveries. Who You Are: You have a Ph.D. in Immunology, Cancer Biology, Systems Biology, with a proven track record of high impact research accomplishments. You have advanced at least one project as evidenced by a first author paper published or accepted in a leading peer-reviewed journal. You are a highly independent and driven scientist who enjoys working at the bench and the computer. You have a strong passion for scientific research. Qualifications: Knowledge and hands-on experience in cancer immunology or related fields. Ability to learn, adapt, and apply computational tools as part of an experimental research program. You value careful experimental design, quantitative rigor, and clear biological interpretation. You communicate effectively and thrive in a collaborative, interdisciplinary environment. Preferred Qualifications: Experience generating and analyzing single-cell transcriptomic or multi-omic data (e.g., sc RNA-seq, CITE-seq, ATAC-seq) is highly desirable. Experience investigating immune fitness and dysfunction using patient samples and/or preclinical models. Experience integrating experimental and clinical datasets to address translational questions. For information about the Johnston lab at Genentech, please visit: ************************************************************** ************************************************************ The expected salary range for this position based on the primary location of South San Francisco California is $100,00 to $106,500. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed at the link provided below. Benefits Relocation benefits are available for this job posting. Postdoc Program Elevate your research career to new heights with Genetech's Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions. The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader. The Genentech Postdoc Program provides access to world-class seminars, professional development workshops, and networking opportunities. Apply now to Genentech Postdoctoral Program and unlock your full potential! #LI-PL1 #postdoc Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
$106.5k yearly Auto-Apply 3d ago
Postdoctoral Fellow- Biological Chemistry, Kirchhofer lab
Genentech 4.5
Doctoral fellow job at Genentech
A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Genentech. The Opportunity We are seeking a highly motivated postdoctoral fellow to join the laboratory of Dr. Daniel Kirchhofer in the Department of Biological Chemistry at Genentech. This position offers an exciting opportunity to use state-of-the-art peptide display technologies - including phage and mRNA display of macrocyclic and cystine-knot peptide libraries - to discover peptides that modulate the function of therapeutically relevant protein targets. A major focus will be on members of the type II transmembrane serine protease family, cell-surface enzymes implicated in disease processes such as viral entry. In parallel, you will engineer disulfide-constrained peptide libraries designed to engage challenging, flat protein-protein interfaces, using a newly developed scaffold with a unique surface topology, and will leverage machine-learning-assisted methods for peptide sequence optimization. To elucidate mechanisms of peptide activity, the successful candidate will apply a broad range of biochemical, biophysical, structural, and cellular methods. The ideal applicant is an independent, creative scientist who thrives in a collaborative, team-oriented environment. The position offers extensive opportunities to interact with the vibrant Genentech postdoctoral community as well as scientists across multiple departments. Who You Are: A Ph.D. in biochemistry, biophysics, structural biology or related discipline and a proven record of productivity in their graduate career as demonstrated by first-author publications. Preferred Qualifications: Strong experience in molecular biology Expertise in engineering, expressing and purifying proteins Experience with directed evolution (yeast, phage, mRNA display, etc.) is preferred Experience in peptide chemistry is a plus Proficiency in surface plasmon resonance or biolayer interferometry Proficient in structural biology (crystallography and or cryo-EM) is a plus Experience with tissue culture, cell-based assays Strong analytical, collaborative, communication and organizational skills For information about the Kirchhofer Lab at Genentech, please go to: **************************************************************** Postdoc Program Elevate your research career to new heights with Genentech's Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions. The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader. The Genentech Postdoc Program provides access to world-class seminars, professional development workshops, and networking opportunities. Apply now to Genentech Postdoctoral Program and unlock your full potential! The expected salary range for this position based on the primary location of California is $100,000 to $106,500 . Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed at the link provided below. Benefits Relocation benefits are available for this job posting. #LI-PL1 #postdoc Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
$100k-106.5k yearly Auto-Apply 13d ago
Postdoctoral Fellow, Research Oncology, Ashkenazi Lab
Genentech 4.5
Doctoral fellow job at Genentech
A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Genentech. A Postdoctoral fellow position is available for a highly motivated and independent candidate to join the laboratory of Dr. Avi Ashkenazi in the Department of Research Oncology at Genentech. In broad terms the Ashkenazi lab is interested in the discovery of fundamental biological features of cancer cells that cause unique vulnerabilities to therapeutic intervention and in the development of innovative medicines that leverage such dependencies. More specifically, our lab is interested in understanding extrinsic apoptosis resistance mechanisms in cancer, as well as in the role of endoplasmic-reticulum stress and the unfolded protein response (UPR) in facilitating oncogenic transformation. Furthermore, we are interested in discovering novel therapeutic strategies to disrupt apoptosis resistance and/or UPR-mediated fitness in cancer cells. The Opportunity: * You will have opportunities to conduct your own independent research to make original discoveries, productively collaborate with other researchers across departments, present your work internally and at external scientific conferences, and lead and drive scientiﬁc publications. * As a member of the Ashkenazi lab and the Research Oncology Department, you will work at the cutting edge of scientific discovery and therapeutic translation in the field of cancer * You will participate in Genentech's post-doctoral training program, which provides an outstanding opportunity to pursue exciting basic-science questions in an environment focused on breakthrough discoveries and their translation into life-altering or life-saving medicines. Who You Are: * A Ph.D. with a proven track record of excellence in investigating the biology of cancer * An independent thinker with integrity, strong passion for scientific discovery, outstanding communication skills, and methodological experience in biochemistry, cell biology, computational biology, and in vitro and in vivo cancer modeling. * Have advanced at least one key research project evident by a first-author paper accepted or published in a leading peer-reviewed journal. * Able to work both independently and as a team member. Qualifications: * Theoretical knowledge and hands-on experience in cancer-cell biology and computational biology. * Track record of successfully conducting laboratory experiments. * Ability to formulate scientific questions and hypotheses. * Ability to design, perform, and interpret experiments to test these hypotheses. * Ability to describe scientific findings, summarize them, and explain their significance. * Excellent oral and written communication skills. For information about the Ashkenazi lab at Genentech, please go to: Avi Ashkenazi The expected salary range for this position based on the primary location of South San Francisco California is $98,000 to $104,500. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed at the link provided below. Benefits Relocation benefits are available for this job posting. Postdoc Program Elevate your research career to new heights with Genetech's Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions. The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader. The Genentech Postdoc Program provides access to world-class seminars, professional development workshops, and networking opportunities. Apply now to Genentech Postdoctoral Program and unlock your full potential! #LI-PL1 #postdoc Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
$98k-104.5k yearly 44d ago
Postdoctoral Fellow - Molecular Mechanisms of Neurodegeneration, Bingol Lab
Genentech 4.5
Doctoral fellow job at Genentech
A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Genentech. A postdoctoral fellow position is available for a highly motivated and independent scientist to join the laboratory of Baris Bingol in the Department of Neuroscience at Genentech. The Bingol lab investigates the molecular mechanisms of neurodegeneration, with a particular focus on neuronal and glial proteostasis. This position will center on elucidating the molecular mechanisms of lysosomal and mitochondrial quality control in the context of neurodegenerative diseases, including Alzheimer's Disease, Parkinson's Disease, and Amyotrophic Lateral Sclerosis. This fellowship offers a unique opportunity to contribute to target discovery efforts and to perform mechanistic studies to understand how human genetic variants disrupt organelle and protein quality control pathways. Candidates with a strong track record in mechanistic molecular and cellular neurobiology research are encouraged to apply. The successful candidate will leverage cutting-edge technologies-including proteomics, lipidomics, next-generation sequencing, CRISPR, iPSC-derived and primary culture models, in vivo systems, and AI/ML-supported computational biology-to uncover fundamental disease mechanisms. The Opportunity * Collaborate productively with researchers across departments, present your work to project teams, and publish as first author on scientific publications. * Join a vibrant Neuroscience community that includes leaders in discovering the molecular causes and therapeutic targets for neurodegenerative diseases. * Participate in the Genentech Postdoctoral Program, which provides an exceptional environment for pursuing fundamental scientific questions and driving breakthrough discoveries. Who You Are * Ph.D. in a relevant field with a strong track record of excellence in cellular and molecular neuroscience. * Must have advanced at least one key research project focusing on mechanistic research, as evidenced by a first-author paper published or accepted in a leading peer-reviewed journal. * An independent, resilient scientist with outstanding communication skills and a strong intrinsic drive, who thrives in a collaborative team environment. * Motivated by identifying novel therapeutic targets for neurodegenerative diseases. Preferred Qualifications * Hands-on experience with iPSC-based cultures of CNS cell types, primary rodent cultures, and genetic perturbation methods. * Deep understanding of molecular mechanisms relevant to neurodegeneration, particularly mitochondrial or lysosomal pathways. * Proven track record of success in wet-laboratory experimentation. * Working knowledge of large-scale data analysis (e.g., RNA-seq, proteomics). * Excellent data organization, presentation, and communication skills. For more information about the Bingol Lab, please see link below: *********************************************************** The expected salary range for this position based on the primary location of California is $98,000 to $104,500 . Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed at the link provided below. Benefits Relocation benefits are available for this job posting. Postdoc Program Elevate your research career to new heights with Genetech's Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions. The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader. The Genentech Postdoc Program provides access to world-class seminars, professional development workshops, and networking opportunities. Apply now to the Genentech Postdoctoral Program and unlock your full potential! #LI-PL1 #postdoc Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
$98k-104.5k yearly 45d ago
Postdoctoral Fellow - Molecular Mechanisms of Neurodegeneration, Bingol Lab
Genentech 4.5
Doctoral fellow job at Genentech
** A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Genentech. A postdoctoral fellow position is available for a highly motivated and independent scientist to join the laboratory of Baris Bingol in the Department of Neuroscience at Genentech. The Bingol lab investigates the molecular mechanisms of neurodegeneration, with a particular focus on neuronal and glial proteostasis. This position will center on elucidating the molecular mechanisms of lysosomal and mitochondrial quality control in the context of neurodegenerative diseases, including Alzheimer's Disease, Parkinson's Disease, and Amyotrophic Lateral Sclerosis. This fellowship offers a unique opportunity to contribute to target discovery efforts and to perform mechanistic studies to understand how human genetic variants disrupt organelle and protein quality control pathways. Candidates with a strong track record in mechanistic molecular and cellular neurobiology research are encouraged to apply. The successful candidate will leverage cutting-edge technologies-including proteomics, lipidomics, next-generation sequencing, CRISPR, iPSC-derived and primary culture models, in vivo systems, and AI/ML-supported computational biology-to uncover fundamental disease mechanisms. **The Opportunity** + Collaborate productively with researchers across departments, present your work to project teams, and publish as first author on scientific publications. + Join a vibrant Neuroscience community that includes leaders in discovering the molecular causes and therapeutic targets for neurodegenerative diseases. + Participate in the Genentech Postdoctoral Program, which provides an exceptional environment for pursuing fundamental scientific questions and driving breakthrough discoveries. **Who You Are** + Ph.D. in a relevant field with a strong track record of excellence in cellular and molecular neuroscience. + Must have advanced at least one key research project focusing on mechanistic research, as evidenced by a first-author paper published or accepted in a leading peer-reviewed journal. + An independent, resilient scientist with outstanding communication skills and a strong intrinsic drive, who thrives in a collaborative team environment. + Motivated by identifying novel therapeutic targets for neurodegenerative diseases. **Preferred Qualifications** + Hands-on experience with iPSC-based cultures of CNS cell types, primary rodent cultures, and genetic perturbation methods. + Deep understanding of molecular mechanisms relevant to neurodegeneration, particularly mitochondrial or lysosomal pathways. + Proven track record of success in wet-laboratory experimentation. + Working knowledge of large-scale data analysis (e.g., RNA-seq, proteomics). + Excellent data organization, presentation, and communication skills. For more information about the Bingol Lab, please see link below: *********************************************************** The expected salary range for this position based on the primary location of California is $98,000 to $104,500 . Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed at the link provided below. Benefits (**************************************************** Relocation benefits are available for this job posting. **Postdoc Program** Elevate your research career to new heights with Genetech's Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions. The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader. The Genentech Postdoc Program (************************************************ provides access to world-class seminars, professional development workshops, and networking opportunities. Apply now to the Genentech Postdoctoral Program and unlock your full potential! \#LI-PL1 \#postdoc Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants (***************************************************************************************************** .
$98k-104.5k yearly 44d ago
Postdoctoral Fellow - RNA Delivery, Yen/Fan/Emani Labs
Genentech 4.5
Doctoral fellow job at Genentech
** We advance science so that we all have more time with the people we love. A postdoctoral fellow position is available for a highly motivated and independent candidate to join the laboratory of Dr. Chun-Wan Yen and Dr. Yuchen Fan in the Department of Synthetic Molecule Pharmaceutical Science (SMPS) at Genentech and Dr. Maheswara Reddy Emani in Biochemical Cellular Pharmacology (BCP) department. The position focuses on drug delivery development, with an emphasis on nanomedicine and lipid nanoparticle (LNP) enabled RNA delivery. We are committed to advancing the understanding of structure-activity relationships between LNP design and biological performance. This postdoctoral role offers an opportunity to investigate the innate immune response to RNA delivery. The fellow will work within a joint research environment between SMPS and BCP departments, contributing to the development of ML/AI models for LNP formulation and characterization, as well as the development of in vitro systems. The Opportunity: + This position will also work closely with mentors in immunology discovery and AI Machine Learning teams to establish a predictive model between RNA/lipid nanoparticle and immune stimulations. + As a member of the joint departments, you will have cross-functional collaborations. + Join the Genentech Postdoctoral Program, which offers outstanding training and mentorship, opportunities to present work internally and externally, and a strong focus on career development. Who You Are: + Ph.D. in chemistry, biochemistry, biomedical engineering, or a related discipline + Demonstrated strong research track record, including first-author publications, and a passion for solving scientific problems through creative approaches + Excellent communication and presentation skills Preferred Qualifications: + Familiarity with relevant experimental techniques, including hands-on experience with cell culture, in vitro assay development, and knowledge of LNP workflows + Experience with machine learning or data mining is a plus For information about the Yen lab at Genentech, please go to: *********************************************************** The expected salary range for this position based on the primary location of South San Francisco California is $98,000 to $104,500. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed at the link provided below. Benefits (**************************************************** Relocation benefits are available for this job posting. **Postdoc Program** Elevate your research career to new heights with Genetech's Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions. The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader. The Genentech Postdoc Program (************************************************ provides access to world-class seminars, professional development workshops, and networking opportunities. Apply now to Genentech Postdoctoral Program and unlock your full potential! \#LI-PL1 \#postdoc Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants (***************************************************************************************************** .
$98k-104.5k yearly 46d ago
Postdoctoral Fellow, Research Oncology, Ashkenazi Lab
Genentech 4.5
Doctoral fellow job at Genentech
** A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Genentech. A Postdoctoral fellow position is available for a highly motivated and independent candidate to join the laboratory of Dr. Avi Ashkenazi in the Department of Research Oncology at Genentech. In broad terms the Ashkenazi lab is interested in the discovery of fundamental biological features of cancer cells that cause unique vulnerabilities to therapeutic intervention and in the development of innovative medicines that leverage such dependencies. More specifically, our lab is interested in understanding extrinsic apoptosis resistance mechanisms in cancer, as well as in the role of endoplasmic-reticulum stress and the unfolded protein response (UPR) in facilitating oncogenic transformation. Furthermore, we are interested in discovering novel therapeutic strategies to disrupt apoptosis resistance and/or UPR-mediated fitness in cancer cells. **The Opportunity:** + You will have opportunities to conduct your own independent research to make original discoveries, productively collaborate with other researchers across departments, present your work internally and at external scientific conferences, and lead and drive scientiﬁc publications. + As a member of the Ashkenazi lab and the Research Oncology Department, you will work at the cutting edge of scientific discovery and therapeutic translation in the field of cancer + You will participate in Genentech's post-doctoral training program, which provides an outstanding opportunity to pursue exciting basic-science questions in an environment focused on breakthrough discoveries and their translation into life-altering or life-saving medicines. **Who You Are:** + A Ph.D. with a proven track record of excellence in investigating the biology of cancer + An independent thinker with integrity, strong passion for scientific discovery, outstanding communication skills, and methodological experience in biochemistry, cell biology, computational biology, and in vitro and in vivo cancer modeling. + Have advanced at least one key research project evident by a first-author paper accepted or published in a leading peer-reviewed journal. + Able to work both independently and as a team member. **Qualifications:** + Theoretical knowledge and hands-on experience in cancer-cell biology and computational biology. + Track record of successfully conducting laboratory experiments. + Ability to formulate scientific questions and hypotheses. + Ability to design, perform, and interpret experiments to test these hypotheses. + Ability to describe scientific findings, summarize them, and explain their significance. + Excellent oral and written communication skills. For information about the Ashkenazi lab at Genentech, please go to: Avi Ashkenazi (************************************************************* The expected salary range for this position based on the primary location of South San Francisco California is $98,000 to $104,500. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed at the link provided below. Benefits (**************************************************** Relocation benefits are available for this job posting. Postdoc Program Elevate your research career to new heights with Genetech's Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions. The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader. The Genentech Postdoc Program (************************************************ provides access to world-class seminars, professional development workshops, and networking opportunities. Apply now to Genentech Postdoctoral Program and unlock your full potential! \#LI-PL1 \#postdoc Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants (***************************************************************************************************** .
$98k-104.5k yearly 44d ago
Postdoctoral Fellow, Research Oncology, Ashkenazi Lab
Genentech 4.5
Doctoral fellow job at Genentech
A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Genentech. A Postdoctoral fellow position is available for a highly motivated and independent candidate to join the laboratory of Dr. Avi Ashkenazi in the Department of Research Oncology at Genentech. In broad terms the Ashkenazi lab is interested in the discovery of fundamental biological features of cancer cells that cause unique vulnerabilities to therapeutic intervention and in the development of innovative medicines that leverage such dependencies. More specifically, our lab is interested in understanding extrinsic apoptosis resistance mechanisms in cancer, as well as in the role of endoplasmic-reticulum stress and the unfolded protein response (UPR) in facilitating oncogenic transformation. Furthermore, we are interested in discovering novel therapeutic strategies to disrupt apoptosis resistance and/or UPR-mediated fitness in cancer cells. The Opportunity: You will have opportunities to conduct your own independent research to make original discoveries, productively collaborate with other researchers across departments, present your work internally and at external scientific conferences, and lead and drive scientiﬁc publications. As a member of the Ashkenazi lab and the Research Oncology Department, you will work at the cutting edge of scientific discovery and therapeutic translation in the field of cancer You will participate in Genentech's post-doctoral training program, which provides an outstanding opportunity to pursue exciting basic-science questions in an environment focused on breakthrough discoveries and their translation into life-altering or life-saving medicines. Who You Are: A Ph.D. with a proven track record of excellence in investigating the biology of cancer An independent thinker with integrity, strong passion for scientific discovery, outstanding communication skills, and methodological experience in biochemistry, cell biology, computational biology, and in vitro and in vivo cancer modeling. Have advanced at least one key research project evident by a first-author paper accepted or published in a leading peer-reviewed journal. Able to work both independently and as a team member. Qualifications: Theoretical knowledge and hands-on experience in cancer-cell biology and computational biology. Track record of successfully conducting laboratory experiments. Ability to formulate scientific questions and hypotheses. Ability to design, perform, and interpret experiments to test these hypotheses. Ability to describe scientific findings, summarize them, and explain their significance. Excellent oral and written communication skills. For information about the Ashkenazi lab at Genentech, please go to: Avi Ashkenazi The expected salary range for this position based on the primary location of South San Francisco California is $98,000 to $104,500. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed at the link provided below. Benefits Relocation benefits are available for this job posting. Postdoc Program Elevate your research career to new heights with Genetech's Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions. The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader. The Genentech Postdoc Program provides access to world-class seminars, professional development workshops, and networking opportunities. Apply now to Genentech Postdoctoral Program and unlock your full potential! #LI-PL1 #postdoc Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
$98k-104.5k yearly Auto-Apply 45d ago
Postdoctoral Fellow - Molecular Mechanisms of Neurodegeneration, Bingol Lab
Genentech 4.5
Doctoral fellow job at Genentech
A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Genentech. A postdoctoral fellow position is available for a highly motivated and independent scientist to join the laboratory of Baris Bingol in the Department of Neuroscience at Genentech. The Bingol lab investigates the molecular mechanisms of neurodegeneration, with a particular focus on neuronal and glial proteostasis. This position will center on elucidating the molecular mechanisms of lysosomal and mitochondrial quality control in the context of neurodegenerative diseases, including Alzheimer's Disease, Parkinson's Disease, and Amyotrophic Lateral Sclerosis. This fellowship offers a unique opportunity to contribute to target discovery efforts and to perform mechanistic studies to understand how human genetic variants disrupt organelle and protein quality control pathways. Candidates with a strong track record in mechanistic molecular and cellular neurobiology research are encouraged to apply. The successful candidate will leverage cutting-edge technologies-including proteomics, lipidomics, next-generation sequencing, CRISPR, iPSC-derived and primary culture models, in vivo systems, and AI/ML-supported computational biology-to uncover fundamental disease mechanisms. The Opportunity Collaborate productively with researchers across departments, present your work to project teams, and publish as first author on scientific publications. Join a vibrant Neuroscience community that includes leaders in discovering the molecular causes and therapeutic targets for neurodegenerative diseases. Participate in the Genentech Postdoctoral Program, which provides an exceptional environment for pursuing fundamental scientific questions and driving breakthrough discoveries. Who You Are Ph.D. in a relevant field with a strong track record of excellence in cellular and molecular neuroscience. Must have advanced at least one key research project focusing on mechanistic research, as evidenced by a first-author paper published or accepted in a leading peer-reviewed journal. An independent, resilient scientist with outstanding communication skills and a strong intrinsic drive, who thrives in a collaborative team environment. Motivated by identifying novel therapeutic targets for neurodegenerative diseases. Preferred Qualifications Hands-on experience with iPSC-based cultures of CNS cell types, primary rodent cultures, and genetic perturbation methods. Deep understanding of molecular mechanisms relevant to neurodegeneration, particularly mitochondrial or lysosomal pathways. Proven track record of success in wet-laboratory experimentation. Working knowledge of large-scale data analysis (e.g., RNA-seq, proteomics). Excellent data organization, presentation, and communication skills. For more information about the Bingol Lab, please see link below: *********************************************************** The expected salary range for this position based on the primary location of California is $98,000 to $104,500 . Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed at the link provided below. Benefits Relocation benefits are available for this job posting. Postdoc Program Elevate your research career to new heights with Genetech's Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions. The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader. The Genentech Postdoc Program provides access to world-class seminars, professional development workshops, and networking opportunities. Apply now to the Genentech Postdoctoral Program and unlock your full potential! #LI-PL1 #postdoc Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
$98k-104.5k yearly Auto-Apply 29d ago
Postdoctoral Fellow - Antibody Engineering, Koerber lab
Genentech 4.5
Doctoral fellow job at Genentech
A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Genentech. A Postdoctoral fellow position is available for a highly motivated and independent candidate to join the laboratory of Dr. JT Koerber in the Department of Antibody Engineering at Genentech. The Koerber lab leverages antibody and protein engineering to design novel tools and formats to discover new biological insights or mechanisms of action. This position will focus on engineering strategies to control the activity of antibodies. This postdoctoral position will provide an opportunity to develop skills in antibody engineering and collaborate with experts to lead in vitro and in vivo characterization of their function. Candidates with a passion for protein engineering are especially encouraged to apply. The Opportunity: You will have opportunities to productively collaborate with other researchers across departments, present your work to project teams, and contribute to scientiﬁc publications. As a member of the Antibody Engineering Department, you will join leaders in developing cutting-edge protein engineering strategies You will be part of the Genentech post-doctoral training program that provides an outstanding environment and the opportunity to pursue fundamental basic science questions in an environment focused on drug development and breakthrough discoveries. Who You Are: Ph.D. with a proven track record of excellence in structural biology, biological engineering, or protein engineering Must have advanced at least one key research project as evidenced by a first author paper published or accepted in a leading peer-reviewed journal. Independent scientist with outstanding communication skills, a strong passion and commitment to science and protein engineering, who works well within a team Preferred Qualifications: Experience with molecular biology and proteins is highly desired Track record of successfully conducting laboratory experiments Working knowledge of biochemical techniques is a plus. For information about the Koerber lab at Genentech, please go to: ********************************************************* ****************************************************************** The expected salary range for this position based on the primary location of South San Francisco California is $98,000 to $104,500. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed at the link provided below. Benefits Relocation benefits are available for this job posting. Postdoc Program Elevate your research career to new heights with Genetech's Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions. The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader. The Genentech Postdoc Program provides access to world-class seminars, professional development workshops, and networking opportunities. Apply now to Genentech Postdoctoral Program and unlock your full potential! #LI-PL1 #postdoc Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
$98k-104.5k yearly Auto-Apply 41d ago
Postdoctoral Fellow, Proteomics and Neuroscience, Ori/Bingol Lab
Genentech 4.5
Doctoral fellow job at Genentech
We advance science so that we all have more time with the people we love. The Proteomics and Genomics Technologies department develops and employs innovative proteomic and genomic technologies to advance basic research programs as well as support a multitude of modalities across Genentech's therapeutic pipeline. The Neuroscience department aims to discover novel pathogenic mechanisms of neurodegeneration with the ultimate aim of targeting them to alleviate disease. A position is available for a postdoctoral fellow with expertise in molecular and cellular neuroscience, iPSC-derived models, and omics data to join the Departments of Proteomics and Genomics Technologies and Neuroscience at Genentech, Inc. We have in-house cutting-edge technologies including proteomics, lipidomics, NGS, CRISPR screens, in vitro and in vivo models, and AI/ML-supported computational biology. The Opportunity Active areas of research include mechanistic investigation of the impact of disease on key cellular organelles including mitochondria and lysosomes, and high-throughput proteome profiling of perturbations in iPSC-derived brain cell types. The project will entail a combination of unbiased discovery and hypothesis-driven research to derive causal relationships between pathways contributing to neurodegeneration. You will be responsible for the generation of large-scale datasets, derivation of causal models and follow up mechanistic investigations of novel findings. You will work at the interface between disciplines and leverage expertise from different research areas including proteomics, functional genomics, computational biology and neuroscience. Who You Are: Candidates must have a Ph.D. in biology, biophysics, biochemistry or a related discipline. Team player with a fearless attitude to tackle long standing, difficult problems in neuroscience. Strong background in culturing and manipulating iPSC-derived models, organelle biology, CRISPR screens or neuroscience as evidenced by a first author paper published or accepted in peer-reviewed journals. Preferred Qualifications: Strong computational skills to derive mechanistic insights would be advantageous. Highly motivated and capable of independent work in a collaborative and multidisciplinary environment. Previous experience with proteomics is not required. To learn more about the Ori Lab, please see link below: ************************************************************* To learn more about the Bingol Lab, please see link below: *********************************************************** The expected salary range for this position based on the primary location of South San Francisco California is $98,000 and $104,500. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed at the link provided below. Benefits Relocation benefits are available for this position. Postdoc Program Elevate your research career to new heights with Genetech's Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions. The Genentech Postdoc Program provides access to world-class seminars, professional development workshops, and networking opportunities. The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader. #LI-PL1 #postdoc Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
$98k-104.5k yearly Auto-Apply 60d+ ago