Senior Engineer jobs at Genentech - 153 jobs

** As a Senior Principal Mechanical Engineer at Genentech, you'll have the unique opportunity to lead the charge in designing and upgrading advanced mechanical systems for a dynamic and evolving portfolio of facilities spanning over 6 million square feet across South San Francisco, Dixon, and beyond. Acting as a technical authority, you'll drive innovative and efficient solutions for critical mechanical infrastructure, utilities, and HVAC systems that underpin Genentech's cutting-edge operations. Collaborating with cross-functional teams and industry leaders, you'll play a strategic role in shaping site standards, ensuring alignment with emerging technologies, regulatory requirements, and corporate excellence. If you're a seasoned engineer with a passion for innovation, collaboration, and pushing industry boundaries, this pivotal role offers the chance to make a lasting impact across a globally recognized organization. **The Opportunity** **Responsibilities:** **The responsibilities for this position may include, but are not limited to:** + Under the direction of the Director of Design Engineering, the Design Engineering Senior Principal Mechanical Engineer provides technical leadership and accountability for mechanical engineering designs on capital projects and engineering services done at the South San Francisco, Dixon sites and other sites as requested. + This role engages actively in the design and planning of upgrades to critical mechanical infrastructure, utilities and facility HVAC systems across a portfolio of 50+ buildings / ~6M square feet of space. + This role is a respected industry expert and engages with the Roche internal and industry external network to learn, influence and collaborate on new technologies, best practices and standards, bringing this knowledge and expertise to bear so that project designs provide safe, efficient and reliable operations to Genentech customers. **Project Technical Analysis & Design Guidance:** + The primary area of focus for this role will be supporting the execution of a portfolio of projects with technical input and technical coordination in the mechanical engineering area, including design guidance on HVAC, plumbing, fire protection, building controls, automation and energy management. + The Senior Principal Mechanical Engineer will be assigned 2 - 3 large scale projects ($10M and above) and a portfolio of approximately ~20 projects at a time (ranging in size from $50K to $10M each **) for** which they will attend key design meetings and provide design input and technical options analysis. + The projects will be executed by multi-disciplinary teams, and this role will need to align, coordinate input and influence key customers (R&D, Commercial, Pharmaceutical Technical Operations) and stakeholders (Site Operations, SHE and Security) on project designs. **Project Technical Analysis & Design Guidance, continued:** + The Senior Principal Mechanical Engineer will also provide management and oversight of other Mechanical SMEs brought in as required to manage influx of mechanical related work. + A key function of this role will also be to align the many project designs to Roche / Genentech and site specific standards, and to coordinate the scope done on these many small projects into a comprehensive strategy to address needs in this technical area across the site. **Lead Mechanical Design Standard Team:** + SSF Design and Construction executes the design work on portfolio (less than $10M) projects using the services of three alliance engineering firms, each of whom has an assigned mechanical engineering lead. The role will lead a mechanical engineering design sub-team including the representatives of each of these three firms, along with representatives of Site Operations, Environment, Health and Safety (EH&S), and others. + As defined by project needs, this team will be tasked with developing strategies for upgrading deficient areas of the campus through the project portfolio. + This team may also engage in the development and review of design standards. **Site Specific Standards:** + This role will be responsible for developing site specific mechanical design standards. Such standards will be based on Roche/Genentech corporate standards (including corporate "K" directives), but will be customized for the South San Francisco and Dixon sites. + Development of site standards will involve effectively engaging, involving and influencing site leaders, site operations and customer groups, and will involve incorporating new industry technologies and concepts to advance the mechanical infrastructure of the site. + Standards will be updated on a schedule agreed with management, and likely driven by upcoming portfolios of projects in a technical area for which such standards apply. + This role will also be responsible for maintaining updated standards in an accessible online portal available to partner design firms and stakeholders. **Technical Leadership & Industry\Network Engagement:** + The Senior Principal Mechanical Engineer will be the SSF site expert on industry HVAC/Plumbing, BAS trends and new technologies. + As such, a key portion of the role is continuous learning, engagement with the Roche Engineering Network (technical experts within the Roche Global organization and other Roche sites) as well as outside industry organizations, including ASHRAE, ISPE and others. + A portion of the role's time will be spent visiting other sites, attending (and occasionally presenting) at applicable conferences and industry events, and applying learned skills to the execution of projects at the SSF site. **Technical Leadership & Industry\Network Engagement, continued:** + Additionally, a portion of the Senior Principal Mechanical Engineer's time will be spent supporting broad Design Engineering process improvement projects and LEAN initiatives, to improve the processes and functioning of the overall team. **Strategic Partnership & Innovation:** + The Senior Principal Mechanical Engineer will be responsible for driving innovation across the design and construction of building systems, appropriately adopting technologies and delivery approaches which improve building systems performance, cost effectiveness, and reliability. + This role will lead the development of a site-wide mechanical/electrical infrastructure strategy in partnership with Site Ops and Real Estate & Assets focusing on reducing total cost of ownership, improving performance, and ensuring current site needs are fully met while remaining adaptable to future demands. + Additionally, for projects over $10M the role will work with internal and external partners to create and maintain a quality assurance and control program. + This includes developing individual and team capabilities, collaborating with external partners to ensure qualified engineering resources are assigned to Genentech projects, and driving change when performance does not meet expectations. + The Senior Principal Mechanical Engineer will also be the SSF site expert on industry trends and new technologies for performance-based commissioning and data analytics. **Who You Are** **Requirements:** + Bachelor's degree in Mechanical Engineering or equivalent. + 15 years or more pharmaceutical technology experience in industry or academia after receiving their Bachelor's Degree, at least 8 of which involved mechanical system design, construction and\or commissioning and qualification activities. + Working knowledge of ANSI / ASHRAE, NEMA, NFPA, EPA, and OSHA standards as well as relevant chemical industry specific standards and documentation (piping and instrumentation diagrams, process flow diagrams). + Pharmaceutical GMP project mechanical design experience, LEED certification, experience in project management, LEAN / Six Sigma certification, and/or experience working in a campus environment highly desired, but not required. + Must have excellent communication (written/verbal), presentation, leadership, interpersonal, collaborative, conflict resolution, and negotiating skills + Excellent organization and planning skills. + Advanced Microsoft Office and Google Suite skills. + Exceptional teamwork and collaboration skills are essential to facilitate the work of cross-functional and interdepartmental teams. + Must be dependable, provide attention to details, and execute proficiently in coordination tasks. + Self-starter and ability to work with minimum or no supervision. Relocation benefits are not available for this position **.** The expected salary range for this position based on the primary location of California is $159,000.00 - $295,200.00 USD Annual. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below. Benefits (******************************** Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants (***************************************************************************************************** .

A leading genomic technology company in San Diego seeks a Senior Automation Engineer to lead the development and implementation of automation systems in manufacturing. This role requires expertise in automation processes, collaboration across various departments including Production and Quality, and a strong understanding of pertinent regulations. The successful candidate will drive innovation, mentor engineers, and improve project efficiency. A Bachelor's degree in Engineering is required, with competitive compensation and comprehensive benefits package offered. #J-18808-Ljbffr

A leading biotech company in California is seeking an Associate Director of Device Engineering to oversee the lifecycle of drug-device combination products. This role involves leading cross-functional teams, managing product development, and ensuring supply chain continuity. Ideal candidates will have a doctoral degree and extensive experience in medical device commercialization. The company offers competitive compensation and a full benefits package. #J-18808-Ljbffr

## At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.## Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.## We are seeking a Staff Software Engineer for our Hardware Integration and Frameworks (HWI) platform team. This role is critical to our instrument sequencing platforms, serving as the bridge between our firmware/hardware subsystems and the high-level, user facing applications powering our DNA sequencing products. You will drive technical excellence in system architecture, mentor engineers, and ensure the HWI platform scales to meet product requirements across multiple product lines. **Key Responsibilities** Technical Leadership* Own the architectural design and evolution of the HWI software subsystem, ensuring scalability, reliability, and maintainability* Drive subsystem-level architecture decisions and contribute to product-wide technical strategy* Define and enforce engineering standards, best practices, design patterns for hardware/software integration* Evaluate and introduce new technologies and tools to improve development efficiency Software Development* Design and develop critical HWI components using C#/.NET and Linux-based systems* Implement robust interfaces between Hardware Abstraction and Application Layers* Optimize system performance and resource utilization* Create comprehensive testing strategies including unit, automation, and hardware simulation Problem Solving & Risk Management* Independently investigate and resolve complex system-level issues* Proactively identify technical risks and develop mitigation strategies* Debug complex timing, concurrency, and hardware interaction issues* Perform root cause analysis and implement systemic improvements Collaboration & Mentorship* Partner with hardware, firmware, and software teams to define interfaces and integration strategies* Mentor engineers in software design, debugging techniques, and best practices* Build strong relationships across product development functions to align technical solutions with business objectives* Communicate technical concepts effectively to both technical and non-technical stakeholders* Contribute to the long-term product roadmap and help define departmental technical goals **Qualifications** Skills* Strong proficiency in C# and .Net Core* Experience with Linux environments* Proven experience developing hardware abstraction layers and firmware/software integration* Deep understanding of service-oriented architecture, object-oriented analysis and design, event driven design, and other architectural patterns* Experience in REST API design* Multi-threading, synchronization, and concurrent programming Nice to Have* CI/CD pipeline design and implementation* Static analysis tools and security scanning* Performance profiling and optimization* Proficiency with Atlassian tools like Jira and requirements management tools (like Jama)* Basic proficiency in Typescript and Angular Education & Experience* Bachelor's degree in Computer Science, Software Engineering, Electrical Engineering, or related field* 8+ years of professional software development experience#LI-HYBRID### The estimated base salary range for the Staff Software Engineer - Instrument Software role based in the United States of America is: $152,600 - $228,800. Should the level or location of the role change during the hiring process, the applicable base pay range may be updated accordingly. Compensation decisions are dependent on several factors including, but not limited to, an individual's qualifications, location where the role is to be performed, internal equity, and alignment with market data. Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits as innovative as our work, including access to genomics sequencing, family planning, health/dental/vision, retirement benefits, and paid time off.### We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact accommodations@illumina.com. To learn more, visit: ****************************************************************** The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants. This role is not eligible for visa sponsorship. #J-18808-Ljbffr

A leading life sciences company in Pleasanton, CA is looking for an experienced Software Developer III to design Angular applications and integrate them with cloud platforms and dd PCR instruments. Candidates should have 8+ years of software development experience with strong expertise in Angular, RESTful APIs, and AWS. This role involves collaborating with various teams and contributing to architecture decisions. Competitive benefits and a total rewards package are offered. #J-18808-Ljbffr

A leading biotechnology firm in California seeks an experienced professional with a Ph.D. in biochemistry or a related field, or an extensive background in protein therapeutics and antibody engineering. Candidates should have significant experience in advancing therapeutic candidates through preclinical development and be proficient in molecular biology techniques and computational design tools. Excellent collaboration and communication skills are essential for this role. #J-18808-Ljbffr

Working within Bio-Rad's Life Science R&D Group as a Systems Engineer, you will take engineering concepts, requirements and transform them into functional prototypes and finished products that improve healthcare outcomes for people around the world. Leveraging your knowledge of Systems Engineering principles and best practices, you will develop a systems-level approach to defining concepts, designing, integrating and verifying product hardware and solutions that meet our customer's needs. You will also collaborate with a multi-disciplinary team of engineers and scientists, providing your technical knowledge and insights to ensure our products deliver the highest levels of quality and functionality. How You'll Make An Impact: * Apply your technical knowledge of System Engineering principles to develop cost-effective, reliable, and high-quality systems that satisfy customer needs and business requirements. * Influence critical design decisions during design and integration phase with trade-off analysis that clearly communicate data, observations, and results. * Be part of the product concepting and creation process, collaborating cross-functionally to develop system requirements and architecture definitions, system-level test plans, integration of sub-systems and verification of instrument systems. What You Bring: * Education: BS/MS in Electrical, Mechanical, Optical Engineering or equivalent is required. * Work Experience: 8+ yrs experience in Designing, Developing and Sustaining Platforms for analytical applications and commercial instrument systems. * Extensive Hands-on Experience with Thermal, Optical, and Fluidic Systems and Biological applications is essential. * Apply system engineering principles to develop cost-effective, reliable, high-quality systems that satisfy customer needs and business requirements. * Possess a demonstrated track record of successes as a technical project leader. * Translate customer and business requirements into system requirements that define engineering design concepts and drives efficient product development with modern design control processes. * Ensure compliance with quality and regulatory requirements by applying design control processes such as risk management, configuration management, requirements management and verification testing. * Experience in leading and executing product verification and validation testing activities. * Leverage strong communication, presentation, and interpersonal skills to drive and implement decisions. * Coordinate with cross-functional project teams to ensure timelines are met and assists the team to balance costs, timeline, and performance. * Thrive in a multi-disciplinary team and drives our culture by developing trust with senior and junior scientists and engineers. * Continuously expand your knowledge of state-of-the-art principles, theories, and practices of Systems and Reliability Engineering. Total Rewards Package: At Bio-Rad, we're empowered by our purpose and recognize that our employees are as well. That's why we offer a competitive and comprehensive Total Rewards Program that provides value, quality, and inclusivity while satisfying the diverse needs of our evolving workforce. Bio-Rad's robust offerings serve to enrich the overall health, wealth, and wellbeing of our employees and their families through the various stages of an employee's work and life cycle. Benefits: We're proud to offer a variety of options, including competitive medical plans for you and your family, free HSA funds, a new fertility offering with stipend, group life and disability, paid parental leave, 401k plus profit sharing, an employee stock purchase program, a new upgraded and streamlined mental health platform, extensive learning and development opportunities, education benefits, student debt relief program, pet insurance, wellness challenges and support, paid time off, Employee Resource Groups (ERG's), and more! Compensation: The estimated base salary range for this position is $133,900 to $184,200 at the time of posting. Actual compensation will be provided in writing at the time of offer, if applicable, and is based on several factors we believe fairly and accurately impact compensation, including geographic location, experience, knowledge, skills, abilities, and other job permitted factors. This position is eligible for a variable annual bonus, which is dependent upon achievement of your individual objectives and Company performance. Who We Are: For 70 years, Bio-Rad has focused on advancing the discovery process and transforming the fields of science and healthcare. As one of the top five life science companies, we are a global leader in developing, manufacturing, and marketing a broad range of high-quality research and clinical diagnostic products. We help people everywhere live longer, healthier lives. Bio-Rad offers a unique employee experience with collaborative teams that span the globe. Here, you are supported by leadership to build your career and are empowered to drive change that makes an impact you can see. EEO Statement: Bio-Rad is an Equal Employment Opportunity/Affirmative Action employer, and we welcome candidates of all backgrounds. Veterans, people with physical or mental disabilities, and people of all race, color, sex, sexual orientation, gender identity, religion, national origin and citizenship status are encouraged to apply. Agency Non-Solicitation: Bio-Rad does not accept agency resumes, unless the agency has been authorized by a Bio-Rad Recruiting Representative. Please do not submit resumes unless authorized to do so. Bio-Rad will not pay for any fees related to unsolicited resumes. Fraud Alert: Bio-Rad has received reports of individuals posing as Bio-Rad recruiters to obtain information, including personal and financial, from applicants. Beware of these fake "recruiters" and job scams. Click here for more information on this scam and how to avoid it. #LI-PB1 Legal Entity: (USA_1000) Bio-Rad Laboratories, Inc.

Working within Bio-Rad's Life Science R&D Group as a Systems Engineer, you will take engineering concepts, requirements and transform them into functional prototypes and finished products that improve healthcare outcomes for people around the world. Leveraging your knowledge of Systems Engineering principles and best practices, you will develop a systems-level approach to defining concepts, designing, integrating and verifying product hardware and solutions that meet our customer's needs. You will also collaborate with a multi-disciplinary team of engineers and scientists, providing your technical knowledge and insights to ensure our products deliver the highest levels of quality and functionality. How You'll Make An Impact: * Apply your technical knowledge of System Engineering principles to develop cost-effective, reliable, and high-quality systems that satisfy customer needs and business requirements. * Influence critical design decisions during design and integration phase with trade-off analysis that clearly communicate data, observations, and results. * Be part of the product concepting and creation process, collaborating cross-functionally to develop system requirements and architecture definitions, system-level test plans, integration of sub-systems and verification of instrument systems. What You Bring: * Education: BS/MS in Electrical, Mechanical, Optical Engineering or equivalent is required. * Work Experience: 8+ yrs experience in Designing, Developing and Sustaining Platforms for analytical applications and commercial instrument systems. * Extensive Hands-on Experience with Thermal, Optical, and Fluidic Systems and Biological applications is essential. * Apply system engineering principles to develop cost-effective, reliable, high-quality systems that satisfy customer needs and business requirements. * Possess a demonstrated track record of successes as a technical project leader. * Translate customer and business requirements into system requirements that define engineering design concepts and drives efficient product development with modern design control processes. * Ensure compliance with quality and regulatory requirements by applying design control processes such as risk management, configuration management, requirements management and verification testing. * Experience in leading and executing product verification and validation testing activities. * Leverage strong communication, presentation, and interpersonal skills to drive and implement decisions. * Coordinate with cross-functional project teams to ensure timelines are met and assists the team to balance costs, timeline, and performance. * Thrive in a multi-disciplinary team and drives our culture by developing trust with senior and junior scientists and engineers. * Continuously expand your knowledge of state-of-the-art principles, theories, and practices of Systems and Reliability Engineering. Total Rewards Package: At Bio-Rad, we're empowered by our purpose and recognize that our employees are as well. That's why we offer a competitive and comprehensive Total Rewards Program that provides value, quality, and inclusivity while satisfying the diverse needs of our evolving workforce. Bio-Rad's robust offerings serve to enrich the overall health, wealth, and wellbeing of our employees and their families through the various stages of an employee's work and life cycle. Benefits: We're proud to offer a variety of options, including competitive medical plans for you and your family, free HSA funds, a new fertility offering with stipend, group life and disability, paid parental leave, 401k plus profit sharing, an employee stock purchase program, a new upgraded and streamlined mental health platform, extensive learning and development opportunities, education benefits, student debt relief program, pet insurance, wellness challenges and support, paid time off, Employee Resource Groups (ERG's), and more! Compensation: The estimated base salary range for this position is $133,900 to $184,200 at the time of posting. Actual compensation will be provided in writing at the time of offer, if applicable, and is based on several factors we believe fairly and accurately impact compensation, including geographic location, experience, knowledge, skills, abilities, and other job permitted factors. This position is eligible for a variable annual bonus, which is dependent upon achievement of your individual objectives and Company performance. Who We Are: For 70 years, Bio-Rad has focused on advancing the discovery process and transforming the fields of science and healthcare. As one of the top five life science companies, we are a global leader in developing, manufacturing, and marketing a broad range of high-quality research and clinical diagnostic products. We help people everywhere live longer, healthier lives. Bio-Rad offers a unique employee experience with collaborative teams that span the globe. Here, you are supported by leadership to build your career and are empowered to drive change that makes an impact you can see. EEO Statement: Bio-Rad is an Equal Employment Opportunity/Affirmative Action employer, and we welcome candidates of all backgrounds. Veterans, people with physical or mental disabilities, and people of all race, color, sex, sexual orientation, gender identity, religion, national origin and citizenship status are encouraged to apply. Agency Non-Solicitation: Bio-Rad does not accept agency resumes, unless the agency has been authorized by a Bio-Rad Recruiting Representative. Please do not submit resumes unless authorized to do so. Bio-Rad will not pay for any fees related to unsolicited resumes. Fraud Alert: Bio-Rad has received reports of individuals posing as Bio-Rad recruiters to obtain information, including personal and financial, from applicants. Beware of these fake "recruiters" and job scams. Click here for more information on this scam and how to avoid it. #LI-PB1 Legal Entity: (USA_1000) Bio-Rad Laboratories, Inc.

Genentech is establishing a new Campus Development Team (CDT) to oversee the implementation of the Campus Vision Plan (CVP) for the South San Francisco campus. This Senior Principal Mechanical Engineer position provides single-point accountability for the successful end-to-end delivery of all Mechanical systems, with a primary focus on the complex laboratory and research environments within the gRED development. This role will also provide expertise for the supporting Vivarium, Utility Plant, and Electrical Distribution Hub as part of the CVP. The Principal Mechanical Engineer works within a large, cross-functional project organization and serves as the primary technical liaison, coordinating the specific mechanical systems (HVAC, plumbing, fire protection, building controls, automation and energy management) and reliability needs of scientific and vivarium user groups into actionable engineering designs. This position is responsible for ensuring all mechanical systems are delivered safely, on schedule, within budget, and to the highest standards of quality, meeting the critical demands of a world-class R&D and animal care facility. The Opportunity Responsibilities: The responsibilities for this position may include, but are not limited to: ● Provides technical leadership and deep subject matter expertise for the mechanical engineering designs supporting gRED research laboratories, specialized vivarium spaces, and associated supporting projects. ● Actively leads the design and planning of HVAC, plumbing, fire protection, building controls, automation and energy management critical to laboratory operations and specialized vivarium environments. ● Coordinates with the Utility Master Plans to ensure that upgrades to critical mechanical infrastructure (including the Regional Utility Plant and Electrical Distribution Hub) directly support the reliability, redundancy and scalability required by the new lab facilities. ● Serves as a respected industry expert on laboratory mechanical design, engaging with the Roche/Genentech internal and industry external network to learn, influence, and collaborate on new technologies and best practices for gRED. ● Primary focus will be ensuring scientific user requirements are incorporated into robust technical solutions for the gRED project. ● Provide expert design guidance on HVAC, plumbing, fire protection, building controls, automation and energy management to labs and strategies for flexible 'plug-and-play' capabilities, and robust back-up systems to protect critical experiments, data, and animal life-support systems. ● Work closely with other technical leads to ensure seamless integration of HVAC, plumbing, fire protection, building controls, automation and energy management systems with lab-specific platforms like Building Automation Systems (BAS) and environmental monitoring systems. ● Serve as the mechanical SME in all design and user-group meetings, providing clear technical options analysis and advocating for designs that prioritize scientific workflow, flexibility, and safety. ● A key function of this role will also be to ensure all mechanical designs align with Roche/Genentech and site-specific standards, with a particular focus on standards governing laboratory design and vivarium operations. ● Coordinates the mechanical scope into a comprehensive strategy to address the technical needs across all aspects of the gRED project, from main infrastructure to the point-of-use in the lab. ● A portion of the Principal Mechanical Engineer's time will be spent supporting broad Design Engineering & Construction Services process improvement projects and LEAN initiatives, applying these principles to improve the lab design and delivery process. ● The Senior Principal Mechanical Engineer will be responsible for driving innovation in mechanical systems specifically for R&D environments, adopting technologies that improve lab flexibility, energy efficiency, and operational reliability. ● This role will participate in the development of a project-wide mechanical infrastructure strategy, in partnership with the Design team, to ensure the new gRED labs are adaptable for future scientific platforms and technologies, reducing total cost of ownership while maximizing uptime and research continuity. ● A key portion of the role is continuous learning, engagement with the Roche engineering network (technical experts within the Roche Global organization and other Roche sites) as well as outside industry organizations, including ASHRAE, ISPE and others. Key Tasks: ● Project Planning and Coordination: Develop and maintain a comprehensive project plan, coordinating with architects, engineers, and contractors. Apply innovative thinking to proactively identify and mitigate risks, while monitoring progress via KPIs and reporting status to senior management. ● Budgeting and Resource Management: Support the development and management of the project budget, ensuring cost control and effective resource allocation. This role also supports all procurement activities, including vendor selection, contract negotiation, and material acquisitions. ● Stakeholder Management: Build and maintain strong relationships with internal and external stakeholders, fostering collaboration, transparency, and alignment. Serve as a trusted liaison, keeping all parties informed and engaged through regular meetings and progress reports. ● Team Leadership: Provide effective leadership by clarifying roles and fostering a collaborative, motivated work environment. Mentor and guide team members while also contributing strategic design and technical expertise to the facility's construction. ● Quality Control: Implement and enforce strict quality control measures to ensure compliance with industry standards and specifications.. Who You Are Requirements: ● Bachelor's degree in Mechanical Engineering or equivalent. ● 15 years or more pharmaceutical technology experience in industry or academia after receiving their Bachelor's Degree, at least 8 of which involved mechanical system design, construction and\or commissioning and qualification activities. ● Working knowledge of ANSI / ASHRAE, NEMA, NFPA, EPA, and OSHA standards as well as relevant chemical industry specific standards and documentation (piping and instrumentation diagrams, process flow diagrams). ● Pharmaceutical GMP project mechanical design experience, LEED certification, experience in project management, LEAN / Six Sigma certification, and/or experience working in a campus environment highly desired, but not required. ● Must have excellent communication (written/verbal), presentation, leadership, interpersonal, collaborative, conflict resolution, and negotiating skills ● Excellent organization and planning skills. ● Advanced Microsoft Office and Google Suite skills. ● Exceptional teamwork and collaboration skills are essential to facilitate the work of cross-functional and interdepartmental teams. ● Must be dependable, provide attention to details, and execute proficiently in coordination tasks. ● Self-starter and ability to work with minimum or no supervision. Relocation benefits are not available for this posting. The expected salary range for this position based on the primary location of California is $168,10000 - $312,300 USD Annual. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below. Benefits Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at ******************* Job Function: R&D Operations Job Sub Function: Clinical/Medical Operations Job Category: Professional All Job Posting Locations: Santa Clara, California, United States of America Job Description: Johnson & Johnson is hiring for a Senior Field Clinical Engineer - Shockwave Medical to join our team. This role is fully remote. At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at *******************/. Fueled by innovation at the intersection of biology and technology, we're developing the next generation of smarter, less invasive, more personalized treatments. Ready to join a team that's pioneering the development and commercialization of Intravascular Lithotripsy (IVL) to treat complex calcified cardiovascular disease. Our Shockwave Medical portfolio aims to establish a new standard of care for medical device treatment of atherosclerotic cardiovascular disease through its differentiated and proprietary local delivery of sonic pressure waves for the treatment of calcified plaque. The Sr. Field Clinical Engineer is responsible for the development and execution of site-specific recruitment strategies that result in meeting enrollment targets for Shockwave Medical clinical trials. In addition, the Sr. Field Clinical Engineer will provide case support on Shockwave Medical products including Reducer and intravascular lithotripsy (IVL). The Sr. Field Clinical Engineer will play a critical role in clinical studies including device training, case support, and ensuring timely data collection for clinical programs. This work is accomplished with oversight, requires contact with internal stakeholders, frequent travel to clinical trial sites, works closely with physician advisors, and is critical to business success. Essential Job Functions Physician and hospital staff training, and procedural case coverage to ensure the safe and effective use of medical devices. Present clinical study training materials based on investigational plans to support the safe and effective use of medical devices, including study protocol, instructions for use, core lab manuals and case report forms. Provide clinical and technical support for key study investigators and clinical leaders at assigned sites. Partner with other clinical research colleagues to meet business needs in the field including study start-up, site training, data collection for timely database locks and resolution of critical issues. Administrative activities including training to procedures at site level. Collaborate effectively with internal stakeholders (Clinical Affairs, Medical Affairs, Marketing and Medical Education) and external parties (vendors and physician advisors) to ensure Shockwave Medical clinical trials meet established enrollment goals. Collaborate with internal and external stakeholders to develop a repository of recruitment/study awareness materials and tools. Collaborate with internal and external stakeholders to ensure site-specific recruitment plans are implemented and progress tracked. Develop and maintain strong relationships with site investigators and research staff to understand site recruitment and enrollment processes and resolve obstacles to enrollment to meet study goals. Partner with assigned physician advisors to create and deliver recruitment strategies. Partner with vendors that support recruitment activities. Other duties as assigned. Requirements · Bachelor's Degree in a scientific field of study or equivalent work experience. · Minimum of 5 years of relevant experience with at least 3 years of experience directly supporting interventional or surgical procedures within a hospital. · Knowledge and experience in supporting device pre- and/or post-market clinical studies is required including experience running investigational device exemption (IDE) trials. · Thorough knowledge of Good Clinical Practice (GCP) is required. · Ability to attain and maintain hospital credentials. · Ability to work in a fast-paced environment while managing multiple priorities. · Operate as a team and/or independently while demonstrating flexibility to changing requirements. · Experience with electronic data capture (EDC) systems. · Must have excellent verbal and written communication skills. · High attention to detail and accuracy. · Able to manage multiple project teams with guidance · Proficient computer skills (Microsoft Word, Excel, PowerPoint, etc.) · Must be able to travel approximately 80% mostly in the US and Canada, and potentially outside North America. · May be required to lift up to 25 pounds. Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please contact us via *******************/contact-us/careers or contact AskGS to be directed to your accommodation resource. Required Skills: Preferred Skills: The anticipated base pay range for this position is : US $106,250 - $143,750 / Bay Area - $122,400 - $ 165,600 Additional Description for Pay Transparency: Subject to the terms of their respective plans, employees and/or eligible dependents are eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance. Subject to the terms of their respective plans, employees are eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)). This position is eligible to participate in the Company's long-term incentive program. Subject to the terms of their respective policies and date of hire, Employees are eligible for the following time off benefits: Vacation -120 hours per calendar year Sick time - 40 hours per calendar year; for employees who reside in the State of Washington -56 hours per calendar year Holiday pay, including Floating Holidays -13 days per calendar year Work, Personal and Family Time - up to 40 hours per calendar year Parental Leave - 480 hours within one year of the birth/adoption/foster care of a child Condolence Leave - 30 days for an immediate family member: 5 days for an extended family member Caregiver Leave - 10 days Volunteer Leave - 4 days Military Spouse Time-Off - 80 hours Additional information can be found through the link below. *********************************************

As a Senior Principal Mechanical Engineer at Genentech, you'll have the unique opportunity to lead the charge in designing and upgrading advanced mechanical systems for a dynamic and evolving portfolio of facilities spanning over 6 million square feet across South San Francisco, Dixon, and beyond. Acting as a technical authority, you'll drive innovative and efficient solutions for critical mechanical infrastructure, utilities, and HVAC systems that underpin Genentech's cutting-edge operations. Collaborating with cross-functional teams and industry leaders, you'll play a strategic role in shaping site standards, ensuring alignment with emerging technologies, regulatory requirements, and corporate excellence. If you're a seasoned engineer with a passion for innovation, collaboration, and pushing industry boundaries, this pivotal role offers the chance to make a lasting impact across a globally recognized organization. The OpportunityResponsibilities: The responsibilities for this position may include, but are not limited to: Under the direction of the Director of Design Engineering, the Design Engineering Senior Principal Mechanical Engineer provides technical leadership and accountability for mechanical engineering designs on capital projects and engineering services done at the South San Francisco, Dixon sites and other sites as requested. This role engages actively in the design and planning of upgrades to critical mechanical infrastructure, utilities and facility HVAC systems across a portfolio of 50+ buildings / ~6M square feet of space. This role is a respected industry expert and engages with the Roche internal and industry external network to learn, influence and collaborate on new technologies, best practices and standards, bringing this knowledge and expertise to bear so that project designs provide safe, efficient and reliable operations to Genentech customers. Project Technical Analysis & Design Guidance: The primary area of focus for this role will be supporting the execution of a portfolio of projects with technical input and technical coordination in the mechanical engineering area, including design guidance on HVAC, plumbing, fire protection, building controls, automation and energy management. The Senior Principal Mechanical Engineer will be assigned 2 - 3 large scale projects ($10M and above) and a portfolio of approximately ~20 projects at a time (ranging in size from $50K to $10M each) for which they will attend key design meetings and provide design input and technical options analysis. The projects will be executed by multi-disciplinary teams, and this role will need to align, coordinate input and influence key customers (R&D, Commercial, Pharmaceutical Technical Operations) and stakeholders (Site Operations, SHE and Security) on project designs. Project Technical Analysis & Design Guidance, continued: The Senior Principal Mechanical Engineer will also provide management and oversight of other Mechanical SMEs brought in as required to manage influx of mechanical related work. A key function of this role will also be to align the many project designs to Roche / Genentech and site specific standards, and to coordinate the scope done on these many small projects into a comprehensive strategy to address needs in this technical area across the site. Lead Mechanical Design Standard Team: SSF Design and Construction executes the design work on portfolio (less than $10M) projects using the services of three alliance engineering firms, each of whom has an assigned mechanical engineering lead. The role will lead a mechanical engineering design sub-team including the representatives of each of these three firms, along with representatives of Site Operations, Environment, Health and Safety (EH&S), and others. As defined by project needs, this team will be tasked with developing strategies for upgrading deficient areas of the campus through the project portfolio. This team may also engage in the development and review of design standards. Site Specific Standards: This role will be responsible for developing site specific mechanical design standards. Such standards will be based on Roche/Genentech corporate standards (including corporate “K” directives), but will be customized for the South San Francisco and Dixon sites. Development of site standards will involve effectively engaging, involving and influencing site leaders, site operations and customer groups, and will involve incorporating new industry technologies and concepts to advance the mechanical infrastructure of the site. Standards will be updated on a schedule agreed with management, and likely driven by upcoming portfolios of projects in a technical area for which such standards apply. This role will also be responsible for maintaining updated standards in an accessible online portal available to partner design firms and stakeholders. Technical Leadership & Industry\Network Engagement: The Senior Principal Mechanical Engineer will be the SSF site expert on industry HVAC/Plumbing, BAS trends and new technologies. As such, a key portion of the role is continuous learning, engagement with the Roche Engineering Network (technical experts within the Roche Global organization and other Roche sites) as well as outside industry organizations, including ASHRAE, ISPE and others. A portion of the role's time will be spent visiting other sites, attending (and occasionally presenting) at applicable conferences and industry events, and applying learned skills to the execution of projects at the SSF site. Technical Leadership & Industry\Network Engagement, continued: Additionally, a portion of the Senior Principal Mechanical Engineer's time will be spent supporting broad Design Engineering process improvement projects and LEAN initiatives, to improve the processes and functioning of the overall team. Strategic Partnership & Innovation: The Senior Principal Mechanical Engineer will be responsible for driving innovation across the design and construction of building systems, appropriately adopting technologies and delivery approaches which improve building systems performance, cost effectiveness, and reliability. This role will lead the development of a site-wide mechanical/electrical infrastructure strategy in partnership with Site Ops and Real Estate & Assets focusing on reducing total cost of ownership, improving performance, and ensuring current site needs are fully met while remaining adaptable to future demands. Additionally, for projects over $10M the role will work with internal and external partners to create and maintain a quality assurance and control program. This includes developing individual and team capabilities, collaborating with external partners to ensure qualified engineering resources are assigned to Genentech projects, and driving change when performance does not meet expectations. The Senior Principal Mechanical Engineer will also be the SSF site expert on industry trends and new technologies for performance-based commissioning and data analytics. Who You Are Requirements: Bachelor's degree in Mechanical Engineering or equivalent. 15 years or more pharmaceutical technology experience in industry or academia after receiving their Bachelor's Degree, at least 8 of which involved mechanical system design, construction and\or commissioning and qualification activities. Working knowledge of ANSI / ASHRAE, NEMA, NFPA, EPA, and OSHA standards as well as relevant chemical industry specific standards and documentation (piping and instrumentation diagrams, process flow diagrams). Pharmaceutical GMP project mechanical design experience, LEED certification, experience in project management, LEAN / Six Sigma certification, and/or experience working in a campus environment highly desired, but not required. Must have excellent communication (written/verbal), presentation, leadership, interpersonal, collaborative, conflict resolution, and negotiating skills Excellent organization and planning skills. Advanced Microsoft Office and Google Suite skills. Exceptional teamwork and collaboration skills are essential to facilitate the work of cross-functional and interdepartmental teams. Must be dependable, provide attention to details, and execute proficiently in coordination tasks. Self-starter and ability to work with minimum or no supervision. Relocation benefits are not available for this position. The expected salary range for this position based on the primary location of California is $159,000.00 - $295,200.00 USD Annual. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below. Benefits Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

As a Senior Principal Mechanical Engineer at Genentech, you'll have the unique opportunity to lead the charge in designing and upgrading advanced mechanical systems for a dynamic and evolving portfolio of facilities spanning over 6 million square feet across South San Francisco, Dixon, and beyond. Acting as a technical authority, you'll drive innovative and efficient solutions for critical mechanical infrastructure, utilities, and HVAC systems that underpin Genentech's cutting-edge operations. Collaborating with cross-functional teams and industry leaders, you'll play a strategic role in shaping site standards, ensuring alignment with emerging technologies, regulatory requirements, and corporate excellence. If you're a seasoned engineer with a passion for innovation, collaboration, and pushing industry boundaries, this pivotal role offers the chance to make a lasting impact across a globally recognized organization. The Opportunity Responsibilities: The responsibilities for this position may include, but are not limited to: * Under the direction of the Director of Design Engineering, the Design Engineering Senior Principal Mechanical Engineer provides technical leadership and accountability for mechanical engineering designs on capital projects and engineering services done at the South San Francisco, Dixon sites and other sites as requested. * This role engages actively in the design and planning of upgrades to critical mechanical infrastructure, utilities and facility HVAC systems across a portfolio of 50+ buildings / ~6M square feet of space. * This role is a respected industry expert and engages with the Roche internal and industry external network to learn, influence and collaborate on new technologies, best practices and standards, bringing this knowledge and expertise to bear so that project designs provide safe, efficient and reliable operations to Genentech customers. Project Technical Analysis & Design Guidance: * The primary area of focus for this role will be supporting the execution of a portfolio of projects with technical input and technical coordination in the mechanical engineering area, including design guidance on HVAC, plumbing, fire protection, building controls, automation and energy management. * The Senior Principal Mechanical Engineer will be assigned 2 - 3 large scale projects ($10M and above) and a portfolio of approximately ~20 projects at a time (ranging in size from $50K to $10M each) for which they will attend key design meetings and provide design input and technical options analysis. * The projects will be executed by multi-disciplinary teams, and this role will need to align, coordinate input and influence key customers (R&D, Commercial, Pharmaceutical Technical Operations) and stakeholders (Site Operations, SHE and Security) on project designs. Project Technical Analysis & Design Guidance, continued: * The Senior Principal Mechanical Engineer will also provide management and oversight of other Mechanical SMEs brought in as required to manage influx of mechanical related work. * A key function of this role will also be to align the many project designs to Roche / Genentech and site specific standards, and to coordinate the scope done on these many small projects into a comprehensive strategy to address needs in this technical area across the site. Lead Mechanical Design Standard Team: * SSF Design and Construction executes the design work on portfolio (less than $10M) projects using the services of three alliance engineering firms, each of whom has an assigned mechanical engineering lead. The role will lead a mechanical engineering design sub-team including the representatives of each of these three firms, along with representatives of Site Operations, Environment, Health and Safety (EH&S), and others. * As defined by project needs, this team will be tasked with developing strategies for upgrading deficient areas of the campus through the project portfolio. * This team may also engage in the development and review of design standards. Site Specific Standards: * This role will be responsible for developing site specific mechanical design standards. Such standards will be based on Roche/Genentech corporate standards (including corporate "K" directives), but will be customized for the South San Francisco and Dixon sites. * Development of site standards will involve effectively engaging, involving and influencing site leaders, site operations and customer groups, and will involve incorporating new industry technologies and concepts to advance the mechanical infrastructure of the site. * Standards will be updated on a schedule agreed with management, and likely driven by upcoming portfolios of projects in a technical area for which such standards apply. * This role will also be responsible for maintaining updated standards in an accessible online portal available to partner design firms and stakeholders. Technical Leadership & Industry\Network Engagement: * The Senior Principal Mechanical Engineer will be the SSF site expert on industry HVAC/Plumbing, BAS trends and new technologies. * As such, a key portion of the role is continuous learning, engagement with the Roche Engineering Network (technical experts within the Roche Global organization and other Roche sites) as well as outside industry organizations, including ASHRAE, ISPE and others. * A portion of the role's time will be spent visiting other sites, attending (and occasionally presenting) at applicable conferences and industry events, and applying learned skills to the execution of projects at the SSF site. Technical Leadership & Industry\Network Engagement, continued: * Additionally, a portion of the Senior Principal Mechanical Engineer's time will be spent supporting broad Design Engineering process improvement projects and LEAN initiatives, to improve the processes and functioning of the overall team. Strategic Partnership & Innovation: * The Senior Principal Mechanical Engineer will be responsible for driving innovation across the design and construction of building systems, appropriately adopting technologies and delivery approaches which improve building systems performance, cost effectiveness, and reliability. * This role will lead the development of a site-wide mechanical/electrical infrastructure strategy in partnership with Site Ops and Real Estate & Assets focusing on reducing total cost of ownership, improving performance, and ensuring current site needs are fully met while remaining adaptable to future demands. * Additionally, for projects over $10M the role will work with internal and external partners to create and maintain a quality assurance and control program. * This includes developing individual and team capabilities, collaborating with external partners to ensure qualified engineering resources are assigned to Genentech projects, and driving change when performance does not meet expectations. * The Senior Principal Mechanical Engineer will also be the SSF site expert on industry trends and new technologies for performance-based commissioning and data analytics. Who You Are Requirements: * Bachelor's degree in Mechanical Engineering or equivalent. * 15 years or more pharmaceutical technology experience in industry or academia after receiving their Bachelor's Degree, at least 8 of which involved mechanical system design, construction and\or commissioning and qualification activities. * Working knowledge of ANSI / ASHRAE, NEMA, NFPA, EPA, and OSHA standards as well as relevant chemical industry specific standards and documentation (piping and instrumentation diagrams, process flow diagrams). * Pharmaceutical GMP project mechanical design experience, LEED certification, experience in project management, LEAN / Six Sigma certification, and/or experience working in a campus environment highly desired, but not required. * Must have excellent communication (written/verbal), presentation, leadership, interpersonal, collaborative, conflict resolution, and negotiating skills * Excellent organization and planning skills. * Advanced Microsoft Office and Google Suite skills. * Exceptional teamwork and collaboration skills are essential to facilitate the work of cross-functional and interdepartmental teams. * Must be dependable, provide attention to details, and execute proficiently in coordination tasks. * Self-starter and ability to work with minimum or no supervision. Relocation benefits are not available for this position. The expected salary range for this position based on the primary location of California is $159,000.00 - $295,200.00 USD Annual. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below. Benefits Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

** Doing now what patients need next... for a healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Roche. This role is based in Pharma Technical Operations Technology (PTT), an organization that is responsible for ensuring Pharma Technical Operations (PT) stays at the forefront of technology in our current and future facilities. PTT, composed of global MSAT and Engineering, plays a key role in leading seamless industrialization and thorough technical product management through integrating SHE, proactive maintenance, facility fitness, performance optimization, and scalable manufacturing processes and technologies in support of the manufacturing network. In this role, you will have the opportunity to shape the manufacturing network that delivers life saving medicines to patients. **The Opportunity** The Engineering Project Feasibility and Product Sourcing Leader within the PTT Asset Health & Future Assets (AHFA) group conducts early feasibility and product sourcing assessments for Global Engineering CapEx projects. This role ensures that capital investments and investments supporting sourcing decisions align with and enable the Pharma long-range plan. A core responsibility of this role is partnering closely with Network Strategy, Global Product & Supply Chain Management, manufacturing sites, and Finance to develop robust business cases that inform PT governance decisions regarding capital investments and product sourcings. + Secures buy-in from stakeholders and senior leadership, drives cross-functional alignment, and resolves issues within the engineering community and broader network for Global Engineering CapEx projects + Builds robust scenarios that model best- and worst-case outcomes and provide flexibility for informed decision-making in a dynamic business environment + Develops comprehensive business cases for capital projects, maintaining fiduciary responsibility for real estate and equipment assets + Assesses requirements for product launches, technology transfers, and capital investments; ensures assumptions across options are agreed upon and aligned with stakeholders + Conducts complex early feasibility assessments across sites and functions, collaborating closely with senior leaders, subject matter experts, and site engineering teams + Partners with the engineering community/network to apply technology standards that enable successful project outcomes and reduce business risk + Transitions completed early feasibility assessments to Project Initiation teams and contributes as an expert reviewer during project reviews **Who You Are** + Bachelor's degree in Engineering or related field + Minimum of 12 years of Pharmaceutical or Biotech experience, process engineering experience preferred + Minimum of 8 years of management leadership experience in a matrix organization + Experience in a complex global environment with CapEx project execution + International/global experience is strongly preferred + Flexibility for domestic and international travel as required Relocation benefits are not available for this posting. The expected salary range for this position based on the primary location of South San Francisco, California is $156,700 to $290,900. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below. Benefits (**************************************************** \#LI-PK1 Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants (***************************************************************************************************** .

Doing now what patients need next… for a healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Roche. This role is based in Pharma Technical Operations Technology (PTT), an organization that is responsible for ensuring Pharma Technical Operations (PT) stays at the forefront of technology in our current and future facilities. PTT, composed of global MSAT and Engineering, plays a key role in leading seamless industrialization and thorough technical product management through integrating SHE, proactive maintenance, facility fitness, performance optimization, and scalable manufacturing processes and technologies in support of the manufacturing network. In this role, you will have the opportunity to shape the manufacturing network that delivers life saving medicines to patients. The Opportunity The Engineering Project Feasibility and Product Sourcing Leader within the PTT Asset Health & Future Assets (AHFA) group conducts early feasibility and product sourcing assessments for Global Engineering CapEx projects. This role ensures that capital investments and investments supporting sourcing decisions align with and enable the Pharma long-range plan. A core responsibility of this role is partnering closely with Network Strategy, Global Product & Supply Chain Management, manufacturing sites, and Finance to develop robust business cases that inform PT governance decisions regarding capital investments and product sourcings. * Secures buy-in from stakeholders and senior leadership, drives cross-functional alignment, and resolves issues within the engineering community and broader network for Global Engineering CapEx projects * Builds robust scenarios that model best- and worst-case outcomes and provide flexibility for informed decision-making in a dynamic business environment * Develops comprehensive business cases for capital projects, maintaining fiduciary responsibility for real estate and equipment assets * Assesses requirements for product launches, technology transfers, and capital investments; ensures assumptions across options are agreed upon and aligned with stakeholders * Conducts complex early feasibility assessments across sites and functions, collaborating closely with senior leaders, subject matter experts, and site engineering teams * Partners with the engineering community/network to apply technology standards that enable successful project outcomes and reduce business risk * Transitions completed early feasibility assessments to Project Initiation teams and contributes as an expert reviewer during project reviews Who You Are * Bachelor's degree in Engineering or related field * Minimum of 12 years of Pharmaceutical or Biotech experience, process engineering experience preferred * Minimum of 8 years of management leadership experience in a matrix organization * Experience in a complex global environment with CapEx project execution * International/global experience is strongly preferred * Flexibility for domestic and international travel as required Relocation benefits are not available for this posting. The expected salary range for this position based on the primary location of South San Francisco, California is $156,700 to $290,900. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below. Benefits #LI-PK1 Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

Who We Are BioMarin is a global biotechnology company that relentlessly pursues bold science to translate genetic discoveries into new medicines that advance the future of human health. Since our founding in 1997, we have applied our scientific expertise in understanding the underlying causes of genetic conditions to create transformative medicines, using a number of treatment modalities. Using our unparalleled expertise in genetics and molecular biology, we develop medicines for patients with significant unmet medical need. We enlist the best of the best - people with the right technical expertise and a relentless drive to solve real problems - and create an environment that empowers our teams to pursue bold, innovative science. With this distinctive approach to drug discovery, we've produced a diverse pipeline of commercial, clinical and preclinical candidates that have well-understood biology and provide an opportunity to be first-to-market or offer a substantial benefit over existing therapeutic options. About Corporate Groups It takes a village, and at BioMarin our corporate groups are the people behind our success. Groups such as IT, Finance, Legal, Global Compliance & Ethics, and our People Team provide foundational support of all areas of operation at BioMarin. Job Title: Sr. Engineer 1, Facilities & UtilitiesLocation: San Rafael, California Reports To: Associate Director Site Operations SUMMARY DESCRIPTIONThe Site Operations, Facilities & Engineering Group provides technical support, guidance, and strategic vision to ensure that the facilities, utilities, warehouse, and laboratory equipment for BioMarin's domestic operations are designed, operated, and maintained in a manner consistent with regulatory agencies, environmental health & safety and asset lifecycle management best practices. This role will manage external vendors and contractors within a site-based Facilities & Engineering team dedicated to supporting operations across Northern California locations. Reporting to the Associate Director Site Operations you will work closely with REWS, California Facilities & Engineering, Procurement and Laboratory Operations. This role enables the teams at Biomarin to focus on its patient-centered mission, delivering first-in-class and best-in-class therapeutics that provide meaningful advances for those with serious and life-threatening rare genetic diseases. The engineer will be responsible for ongoing support to non-GxP site operations across Northern California campuses to ensure utilities, facilities and equipment performs per its intended use and function. The engineer will be responsible for supporting the design, engineering, and commissioning of new or modified utility systems, as well as non-GxP facilities, laboratory spaces, and administrative office buildings. The engineer will be responsible for supporting the project portfolio of operational expenditure (Opex) and capital expenditure (Capex) projects at each campus, providing facility engineering and equipment advisement, participating in asset lifecycle management (ALM), facility long range planning, and initiating team improvement projects. The engineer will: Interact collaboratively with key customers, peers, and other stakeholders to support achieving BioMarin tactical and strategic goals & objectives. Highlight and submit improvement and investment projects related to facilities and utilities systems. Work with end users to develop system requirements, specification of equipment/buildings, review design from outside engineering firms or contractors (as needed). Participate in long-term strategic development of site utility system, facilities and energy efficiency programs. May be requested to support other opportunities as directed by management. Work closely with other support groups such as Maintenance, Metrology, Automation, Capital Projects, EHS&S, Facilities, Laboratory Operations and Security to assure that BioMarin assets are well managed throughout their lifecycle. Provide coaching, mentoring and guidance for junior engineers and may be designated as a subject matter expert for one or more clean/dirty utility systems. RESPONSIBILITIES Represent the Engineering, Facilities and Services department, collaborate, and provide advisement on non-GMP facility, utility, and equipment capital projects for Northern California campuses. Monitor and report on the status of the non-GxP campus goals and objectives to ensure they are aligned with BioMarin enterprise strategy. Provide Engineering support of non-GxP laboratories and their associated Facilities/Utilities systems. Act as the Facilities Engineering resource on cross-functional project teams. Collaborate, monitor, and evaluate the asset lifecycle management of non-GMP related facility systems, utility systems and equipment, assess failure risks and asset replacement planning activities. Consult on the long-range planning to ensure asset replacement is scheduled and budgeted to ensure the continuity and availability of business facilities. Partner with EHS&S to support the emergency response team to ensure business continuity and ensure all BioMarin safety policies, procedures, standards, and practices are followed. Successfully plan, execute, and deliver ad-hoc requests, tasks and activities as needed from end users and customers. Demonstrate leadership ability including the ability to lead, motivate, develop, and directly/indirectly manage others effectively. Advance safety, health, and environmental stewardship at BioMarin through technical decisions, guidance, and leadership. Effectively manage internal and external relationships with customers, key stakeholders, and vendors. Demonstrate the ability to be self-directed with limited guidance and oversight from management. Support and drive the development of internal engineering practices and procedures. Effectively apply independent judgment utilizing BioMarin policies, industry practices and BioMarin standards as guidance. Actively participate in technical, tactical, and strategic reviews/discussions. Remain current on all training requirements. Demonstrate the ability to plan and implement small projects. Identify and champion projects and continuous improvement (CI) initiatives that will successfully support BioMarin business goals and objectives. Stay current with leading edge technologies, alternative energy strategies, sustainability trends and best practices through contacts with industry, service/equipment providers, and other formal/informal means. 2 days on site minimum up to 4 days per week presence required with additional time necessary depending on activities. Other duties as assigned. EDUCATIONBS or MS in Chemical, Mechanical, or other Engineering degree from an accredited university. Relevant job and years of experience may be substituted in place of a degree. EXPERIENCE A minimum of 5-7 years' experience in engineering, facilities/lab operations and clean/dirty plant utilities, preferably in the biotechnology or pharmaceutical industry. Highly proficient in deploying, managing, and improving an asset lifecycle management framework, policies, procedures, and practices, conducting equipment risk assessments, maintaining critical asset information, monitoring asset failure history, and recommending asset replacement schedules. Proficient in the relevant aspects of current Good Manufacturing Practices (cGMP), Good Clinical Practices (cGCP) and Good Laboratory Practices (cGLP) Demonstrated successful engineering support of capital projects ranging from $1M to $10M. An understanding and awareness of latest industry standards of environmental sustainability integration to the biopharmaceutical sector (e.g. knowledge of ISO 50001) Demonstrated engineering Subject Matter Expertise (SME) in at least one of the following systems: RO/DI, Clean Dry Air (CDA), clean process gas systems, HVAC, Plant Steam, Chilled water, Condenser Water, Process Wastewater, refrigeration, or electrical systems Strong organization, interpersonal, oral, and written communication skills. Strong analytical and problem solving abilities with strong capability in lab facility related technology. Ability to work in a fast paced, dynamic environment with a high level of Integrity. Proficiency with standard office software applications, including MS Outlook, MS Word, MS Excel, MS Power Point. Proficient in utilizing Purchase Order and Spend Management Systems (e.g., Coupa, SAP, Ariba) Proficiency in creating, editing, and reviewing, engineering/architectural drawings is required. Experience in the use of engineering software tools (e.g. CAD, Bluebeam). BMS JCI MetaSys related experience a plus. WORK ENVIRONMENT / PHYSICAL DEMANDS While primarily a day shift job, hours will vary based on the needs of the position. This position may require additional hours and weekend/holiday work depending upon various facility requirements. Provide after-hours leadership/managerial on-call support as required. While performing the duties of this job the employee is frequently required to stand, walk, sit, talk, or hear, reach with hands and arms, climb stairs or ladders, balance, stoop, kneel, or crouch. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. Lead other Engineers from the team as required. Engineers can be assigned to work with the Engineer to support relevant activities in their area. Lead external consultants to complete critical activities and deliver compliant work on schedule and within budget. Note: This description is not intended to be all-inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned. Equal Opportunity Employer/Veterans/Disabled An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

ITOT supports Pharma Technical Manufacturing (PTM), PTM is responsible for managing all aspects of end-to-end drug substance and drug product manufacturing and supply. From the raw material to the final medicine, we contribute to deliver Roche's ground-breaking therapies to more than 120 million patients around the world. We make our medicines at 9 sites around the world and coordinate all aspects of production of Roche medicines in all disease areas and dosage forms. To ensure readiness for a step-change in the standard of care that Roche delivers in the area of Cardiovascular, Renal and Metabolism (CVRM), PTM will construct a new manufacturing site in the U.S. in Holly Spring, North Carolina. ITOT will own and operate Manufacturing Technology stack at the site working with Global IT. The new site will focus on large volume low cost Drug Product manufacturing (Component Prep & Compounding, Liquid PFS Filling, Automated Inspection, Autoinjector Assembly, Packaging/Finished Products). The Opportunity A Senior Principal Automation Engineer is being hired to participate in Greenfield Project execution and then support the facility after going live. Initially, you will perform a mix of remote and onsite work (first at the General Planner's office, later at construction site/plant). You will transition to local full time on-site work once the site buildings are built and equipment delivered. Travel of up to 30% of the time is expected during the project phase. Senior Principal Automation Engineer (Department: ITOT/Automation Engineering - Leadership Role) will be responsible for providing automation and instrumentation and controls engineering capabilities and experience to the ITOT / Automation Engineering Group including generating qualification protocols and maintaining the validated state of systems and processes. Initially, participates in Basic Design, Detailed Design and Facility Startup. Eventually focuses on providing long-term support for newly built facilities with respect to the automation and instrumentation and control systems for process, utility and building systems. Lead automation impacting projects with large and/or complex scope. Drive strategic initiatives to improve business processes. Be both a People Leader/ Coach and at times hands on SME. What You'll Do * Provide automation, instrumentation, and control engineering design services for facility projects, including upgrades, capacity expansions, and equipment replacements.. * Produce and review design drawings and specification documents (URS, FS, DS, etc.). * Support end-to-end system qualification, including test creation, execution, review and approval. * Manage personal project activities (design and qualification) following Genentech/Roche business processes to deliver results that are right first time, on-time with schedule requirements and reconciled to the budget. * Review and approve vendor information packages, including drawings and specifications as directed to ensure user requirements are met. * Support plant operations to assess discrepant events and changes for automation impact, deliver automation solutions to resolve operational issues, assist in troubleshooting and providing real time on floor support of manufacturing operations, participate in site coordination meetings and attend network meetings. * Author and then Adhere to site SOPs and work instructions for daily and project deliverables. Drive improvements to business processes. * Support inspection activities to present automation design and qualification deliverables and strategy (e.g. Qualification Project Plans and Master Plans). * Adhere to company policies regarding performance management, department time reporting and notification requirements, budget, and expense reporting guidelines. * Automation lead for equipment/software FAT, field testing and commissioning * Provide scope, qualification, resource, and budget estimates for automation impacting projects. * Manage employees/ contractor staff, track project deliverables, and provide status updates to the project team. * Manage teams (contractor and FTE staff) by setting clear expectations for work delivered and behaviors. Monitor performance and ensure contractual obligations are met. Complete timely review of time sheets and invoices. * Provide input into network/global business processes and procedures (e.g. GSPs). * All employees with jobs that require access to the Warehouse must be able to pass the Transportation Security Administration (TSA) Security Threat Assessment (STA). * Ensures the integration of environmental health, safety, and security into the business processes, systems, and programs while reporting safety and environmental incidents including injuries, illnesses, and safety suggestions within one's functional area. Fosters a positive safety culture in which no one gets hurt. * Support work of the Engineering Group, which includes research/evaluate instrumentation and control components, review/modify control system concept/logic as a result of troubleshooting. Who You Are * Bachelor's or Master's degree in Engineering (Chemical, Mechanical, Electrical, or Computer Science preferred) and 8 years experience, or Master's degree in Engineering (Chemical, Mechanical, Electrical, or Computer Science preferred) and 7years experience. * Minimum of 8 years applicable automation and/or instrument and control system experience preferably majority in drug product function * 5 years in the pharmaceutical/biotech industry/GMP experience. * 24X7 on call support, participate in an on-call environment to meet business continuity requirements, including weekends and holidays as required. Knowledge, Skills and Abilities * Experience with Biopharmaceutical manufacturing, design or/and construction. * Knowledge of Industrial Ethernet networks for manufacturing. * Knowledge of vision systems * Knowledge of Drug Product Manufacturing processes including aseptic or robotic fillings systems, vial handling, environmental monitoring and clean utilities. * Knowledge of communication protocols for devices (OPC, Modbus, MQTT, Ethernet IO, IOT) * Knowledge of integration and data transfer with Level 2, 3, and 4 systems. * Qualification experience related to control and computer systems. * Ability to generate engineering drawings and specifications. * Knowledge of ISA standards and practices for instrumentation. * Knowledge of PID control theories and techniques. * Knowledge of programmable logic controllers, and associated programming languages (RS Logix Preferred). * Practical knowledge of process automation systems, and associated programming languages (Rockwell and Siemens preferred). * Demonstrate strong organizational, communication, and interpersonal skills to effectively manage tasks and collaborate with diverse teams. * Ability to comply with cGMP requirements (gowning, documentation, and procedures) for performing work within the manufacturing facility. * Demonstrate strong working knowledge of PC based programs and web based systems. * Ability to work independently with no direct supervision. * Knowledge of GAMP5 * Work in a standard office environment. * May work in the clean room environment that requires gowning in the form of hospital scrubs, coveralls, gloves and steel toe boots. No make-up or jewelry can be worn when working in the clean room environment. * May work with hazardous materials and chemicals. Relocation funding is available for this role. The expected salary range for this position based on the primary location of Holly Springs, North Carolina is $114,400 - $212,400. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below. Benefits Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

** ITOT supports Pharma Technical Manufacturing (PTM), PTM is responsible for managing all aspects of end-to-end drug substance and drug product manufacturing and supply. From the raw material to the final medicine, we contribute to deliver Roche's ground-breaking therapies to more than 120 million patients around the world. We make our medicines at 9 sites around the world and coordinate all aspects of production of Roche medicines in all disease areas and dosage forms. To ensure readiness for a step-change in the standard of care that Roche delivers in the area of Cardiovascular, Renal and Metabolism (CVRM), PTM will construct a new manufacturing site in the U.S. in Holly Spring, North Carolina. ITOT will own and operate Manufacturing Technology stack at the site working with Global IT. The new site will focus on large volume low cost Drug Product manufacturing (Component Prep & Compounding, Liquid PFS Filling, Automated Inspection, Autoinjector Assembly, Packaging/Finished Products). **The Opportunity** A Senior Principal Automation Engineer is being hired to participate in Greenfield Project execution and then support the facility after going live. Initially, you will perform a mix of remote and onsite work (first at the General Planner's office, later at construction site/plant). You will transition to local full time on-site work once the site buildings are built and equipment delivered. Travel of up to 30% of the time is expected during the project phase. Senior Principal Automation Engineer (Department: ITOT/Automation Engineering - Leadership Role) will be responsible for providing automation and instrumentation and controls engineering capabilities and experience to the ITOT / Automation Engineering Group including generating qualification protocols and maintaining the validated state of systems and processes. Initially, participates in Basic Design, Detailed Design and Facility Startup. Eventually focuses on providing long-term support for newly built facilities with respect to the automation and instrumentation and control systems for process, utility and building systems. Lead automation impacting projects with large and/or complex scope. Drive strategic initiatives to improve business processes. Be both a People Leader/ Coach and at times hands on SME. **What You'll Do** + Provide automation, instrumentation, and control engineering design services for facility projects, including upgrades, capacity expansions, and equipment replacements.. + Produce and review design drawings and specification documents (URS, FS, DS, etc.). + Support end-to-end system qualification, including test creation, execution, review and approval. + Manage personal project activities (design and qualification) following Genentech/Roche business processes to deliver results that are right first time, on-time with schedule requirements and reconciled to the budget. + Review and approve vendor information packages, including drawings and specifications as directed to ensure user requirements are met. + Support plant operations to assess discrepant events and changes for automation impact, deliver automation solutions to resolve operational issues, assist in troubleshooting and providing real time on floor support of manufacturing operations, participate in site coordination meetings and attend network meetings. + Author and then Adhere to site SOPs and work instructions for daily and project deliverables. Drive improvements to business processes. + Support inspection activities to present automation design and qualification deliverables and strategy (e.g. Qualification Project Plans and Master Plans). + Adhere to company policies regarding performance management, department time reporting and notification requirements, budget, and expense reporting guidelines. + Automation lead for equipment/software FAT, field testing and commissioning + Provide scope, qualification, resource, and budget estimates for automation impacting projects. + Manage employees/ contractor staff, track project deliverables, and provide status updates to the project team. + Manage teams (contractor and FTE staff) by setting clear expectations for work delivered and behaviors. Monitor performance and ensure contractual obligations are met. Complete timely review of time sheets and invoices. + Provide input into network/global business processes and procedures (e.g. GSPs). + All employees with jobs that require access to the Warehouse must be able to pass the Transportation Security Administration (TSA) Security Threat Assessment (STA). + Ensures the integration of environmental health, safety, and security into the business processes, systems, and programs while reporting safety and environmental incidents including injuries, illnesses, and safety suggestions within one's functional area. Fosters a positive safety culture in which no one gets hurt. + Support work of the Engineering Group, which includes research/evaluate instrumentation and control components, review/modify control system concept/logic as a result of troubleshooting. **Who You Are** + Bachelor's or Master's degree in Engineering (Chemical, Mechanical, Electrical, or Computer Science preferred) and 8 years experience, or Master's degree in Engineering (Chemical, Mechanical, Electrical, or Computer Science preferred) and 7years experience. + Minimum of 8 years applicable automation and/or instrument and control system experience preferably majority in drug product function + 5 years in the pharmaceutical/biotech industry/GMP experience. + 24X7 on call support, participate in an on-call environment to meet business continuity requirements, including weekends and holidays as required. Knowledge, Skills and Abilities + Experience with Biopharmaceutical manufacturing, design or/and construction. + Knowledge of Industrial Ethernet networks for manufacturing. + Knowledge of vision systems + Knowledge of Drug Product Manufacturing processes including aseptic or robotic fillings systems, vial handling, environmental monitoring and clean utilities. + Knowledge of communication protocols for devices (OPC, Modbus, MQTT, Ethernet IO, IOT) + Knowledge of integration and data transfer with Level 2, 3, and 4 systems. + Qualification experience related to control and computer systems. + Ability to generate engineering drawings and specifications. + Knowledge of ISA standards and practices for instrumentation. + Knowledge of PID control theories and techniques. + Knowledge of programmable logic controllers, and associated programming languages (RS Logix Preferred). + Practical knowledge of process automation systems, and associated programming languages (Rockwell and Siemens preferred). + Demonstrate strong organizational, communication, and interpersonal skills to effectively manage tasks and collaborate with diverse teams. + Ability to comply with cGMP requirements (gowning, documentation, and procedures) for performing work within the manufacturing facility. + Demonstrate strong working knowledge of PC based programs and web based systems. + Ability to work independently with no direct supervision. + Knowledge of GAMP5 + Work in a standard office environment. + May work in the clean room environment that requires gowning in the form of hospital scrubs, coveralls, gloves and steel toe boots. No make-up or jewelry can be worn when working in the clean room environment. + May work with hazardous materials and chemicals. **Relocation funding is available for this role.** The expected salary range for this position based on the primary location of Holly Springs, North Carolina is $114,400 - $212,400. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below. Benefits (**************************************************** Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants (***************************************************************************************************** .

Doing now what patients need next… for a healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Roche. This role is based in Pharma Technical Operations Technology (PTT), an organization that is responsible for ensuring Pharma Technical Operations (PT) stays at the forefront of technology in our current and future facilities. PTT, composed of global MSAT and Engineering, plays a key role in leading seamless industrialization and thorough technical product management through integrating SHE, proactive maintenance, facility fitness, performance optimization, and scalable manufacturing processes and technologies in support of the manufacturing network. In this role, you will have the opportunity to shape the manufacturing network that delivers life saving medicines to patients. The Opportunity The Engineering Project Feasibility and Product Sourcing Leader within the PTT Asset Health & Future Assets (AHFA) group conducts early feasibility and product sourcing assessments for Global Engineering CapEx projects. This role ensures that capital investments and investments supporting sourcing decisions align with and enable the Pharma long-range plan. A core responsibility of this role is partnering closely with Network Strategy, Global Product & Supply Chain Management, manufacturing sites, and Finance to develop robust business cases that inform PT governance decisions regarding capital investments and product sourcings. Secures buy-in from stakeholders and senior leadership, drives cross-functional alignment, and resolves issues within the engineering community and broader network for Global Engineering CapEx projects Builds robust scenarios that model best- and worst-case outcomes and provide flexibility for informed decision-making in a dynamic business environment Develops comprehensive business cases for capital projects, maintaining fiduciary responsibility for real estate and equipment assets Assesses requirements for product launches, technology transfers, and capital investments; ensures assumptions across options are agreed upon and aligned with stakeholders Conducts complex early feasibility assessments across sites and functions, collaborating closely with senior leaders, subject matter experts, and site engineering teams Partners with the engineering community/network to apply technology standards that enable successful project outcomes and reduce business risk Transitions completed early feasibility assessments to Project Initiation teams and contributes as an expert reviewer during project reviews Who You Are Bachelor's degree in Engineering or related field Minimum of 12 years of Pharmaceutical or Biotech experience, process engineering experience preferred Minimum of 8 years of management leadership experience in a matrix organization Experience in a complex global environment with CapEx project execution International/global experience is strongly preferred Flexibility for domestic and international travel as required Relocation benefits are not available for this posting. The expected salary range for this position based on the primary location of South San Francisco, California is $156,700 to $290,900. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below. Benefits #LI-PK1 Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

Doing now what patients need next… for a healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Roche. This role is based in Pharma Technical Operations Technology (PTT), an organization that is responsible for ensuring Pharma Technical Operations (PT) stays at the forefront of technology in our current and future facilities. PTT, composed of global MSAT and Engineering, plays a key role in leading seamless industrialization and thorough technical product management through integrating SHE, proactive maintenance, facility fitness, performance optimization, and scalable manufacturing processes and technologies in support of the manufacturing network. In this role, you will have the opportunity to shape the manufacturing network that delivers life saving medicines to patients. The Opportunity The Engineering Project Feasibility and Product Sourcing Leader within the PTT Asset Health & Future Assets (AHFA) group conducts early feasibility and product sourcing assessments for Global Engineering CapEx projects. This role ensures that capital investments and investments supporting sourcing decisions align with and enable the Pharma long-range plan. A core responsibility of this role is partnering closely with Network Strategy, Global Product & Supply Chain Management, manufacturing sites, and Finance to develop robust business cases that inform PT governance decisions regarding capital investments and product sourcings. * Secures buy-in from stakeholders and senior leadership, drives cross-functional alignment, and resolves issues within the engineering community and broader network for Global Engineering CapEx projects * Builds robust scenarios that model best- and worst-case outcomes and provide flexibility for informed decision-making in a dynamic business environment * Develops comprehensive business cases for capital projects, maintaining fiduciary responsibility for real estate and equipment assets * Assesses requirements for product launches, technology transfers, and capital investments; ensures assumptions across options are agreed upon and aligned with stakeholders * Conducts complex early feasibility assessments across sites and functions, collaborating closely with senior leaders, subject matter experts, and site engineering teams * Partners with the engineering community/network to apply technology standards that enable successful project outcomes and reduce business risk * Transitions completed early feasibility assessments to Project Initiation teams and contributes as an expert reviewer during project reviews Who You Are * Bachelor's degree in Engineering or related field * Minimum of 12 years of Pharmaceutical or Biotech experience, process engineering experience preferred * Minimum of 8 years of management leadership experience in a matrix organization * Experience in a complex global environment with CapEx project execution * International/global experience is strongly preferred * Flexibility for domestic and international travel as required Relocation benefits are not available for this posting. The expected salary range for this position based on the primary location of South San Francisco, California is $156,700 to $290,900. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below. Benefits #LI-PK1 Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.