Senior Research Fellow jobs at Genentech

A Postdoctoral fellow position is available for a highly motivated and independent candidate to join the laboratory of Dr. Domagoj Vucic in the Department of Immunology Discovery at Genentech. Vucic lab works on inflammatory signaling pathways with the aim of identifying novel targets in the field of inflammatory diseases. This position will focus on TNF family signaling, particularly on TNF (Tumor Necrosis Factor) and TL1A (TNF-like ligand 1A). Several anti-TL1A antibodies have shown remarkable efficacy in Inflammatory Bowel Disease (IBD) clinical trials but mechanistic details of TL1A mediated signaling are not fully understood. This postdoctoral position will provide an opportunity to contribute to target discovery and mechanistic examination of TL1A and TNF regulated pathways using in vitro and in vivo experiments related to molecular, cellular and inflammatory biology. Candidates familiar with TNF family signaling and innate immunity are especially encouraged to apply. The Opportunity: * You will have opportunities to productively collaborate with other researchers across departments, present your work to project teams, and contribute to scientific publications. * As a member of the Immunology Discovery Department, you will join leaders in identifying molecular causes and targets for immune-inflammatory diseases * You will be part of the Genentech post-doctoral training program that provides an outstanding environment and the opportunity to pursue fundamental basic science questions in an environment focused on drug development and breakthrough discoveries. Who You Are: * Ph.D. with a proven track record of excellence in cellular/ molecular biology and/or immunology * Must have advanced at least one key research project as evidenced by a first author paper published or accepted in a leading peer-reviewed journal. * Independent scientist with outstanding communication skills, a strong passion and commitment to science and inflammatory signaling, who works well within a team * Excited about identifying novel targets for treatments of inflammatory diseases Preferred Qualifications: * Hands-on experience in inflammatory signaling studies is highly desired * Track record of successfully conducting laboratory experiments * Working knowledge of biochemical techniques is a plus. For information about the Vucic lab at Genentech, please go to: ************************************************************ ***************************************************************** The expected salary range for this position based on the primary location of South San Francisco California is $98,000 to $104,500. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed at the link provided below. Benefits Relocation benefits are available for this job posting. Postdoc Program Elevate your research career to new heights with Genetech's Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions. The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader. The Genentech Postdoc Program provides access to world-class seminars, professional development workshops, and networking opportunities. Apply now to Genentech Postdoctoral Program and unlock your full potential! Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

Agilent inspires and supports discoveries that advance the quality of life. We provide life science, diagnostic and applied market laboratories worldwide with instruments, services, consumables, applications and expertise. Agilent enables customers to gain the answers and insights they seek ---- so they can do what they do best: improve the world around us. Information about Agilent is available at **************** The Center of Excellence for Companion Diagnostics develops assays, which support the development of new cancer drugs within the field of precision medicine. See ****************************************** for details. Want to build a career in a dynamic, results-focused environment? Join the team that's providing technical design support for R&D products, recommends changes and formulates techniques that enhance design for performance. Here, you'll work on technical design support assignments and provide solutions, learning continuously through ongoing training and on-the-job experience. We are looking for a talented and dedicated biologist/biochemist to join the CDx Group in our R&D Department. You will provide technical support to develop accurate, robust and precise assays. Your challenge will be to create value for Agilent through innovative ideas that either create new businesses or enhance existing ones. You will work in a cross-functional team on the following activities: •Performs research and/or development in collaboration with others to develop immunohistochemistry (IHC), in situ hybridization (ISH) assays based on new and existing methodologies. •May conduct testing of analytical samples for the laboratory area. •Conducts work in compliance with GMP (as required), safety and regulatory requirements. •May provide analysis and evaluation of material and products at all stages of development process. •Makes detailed observations, analyzes data and interprets results. •Maintains high level of professional expertise through familiarity with scientific literature. •Perform routine analysis using automated platforms and instrumentation •Initially exposed to scientific protocol and report writing •Developing professional skills to apply that knowledge in a business environment. •Executes assignments with defined objectives in area of specialization. •Exchanges knowledge and information within team/group; coordinates and plans activities with others. •Has theoretical or technical knowledge typically acquired through higher education. •Works on research associate assignments with clearly defined objectives •Solves problems of limited scope and complexity •Applies problem solving techniques to determine a course of action within area of responsibility. •Receives general instructions on work and new assignments; work generally reviewed for accuracy. •Applies knowledge to identify solutions to problems of a defined scope. •Scope of responsibility and complexity of duties increasing over time with proficiency. Qualifications Bachelor's Degree preferred. This is an entry level position which requires minimal to no prior relevant work experience. #LI-PK1 Additional Details This job has a full time weekly schedule. Applications for this job will be accepted until at least October 22, 2025 or until the job is no longer posted.The full-time equivalent pay range for this position is $56,838.00 - $88,810.00/yr plus eligibility for bonus, stock and benefits. Our pay ranges are determined by role, level, and location. Within the range, individual pay is determined by work location and additional factors, including job-related skills, experience, and relevant education or training. During the hiring process, a recruiter can share more about the specific pay range for a preferred location. Pay and benefit information by country are available at: ************************************* Agilent Technologies, Inc. is an Equal Employment Opportunity and merit-based employer that values individuals of all backgrounds at all levels. All individuals, regardless of personal characteristics, are encouraged to apply. All qualified applicants will receive consideration for employment without regard to sex, pregnancy, race, religion or religious creed, color, gender, gender identity, gender expression, national origin, ancestry, physical or mental disability, medical condition, genetic information, marital status, registered domestic partner status, age, sexual orientation, military or veteran status, protected veteran status, or any other basis protected by federal, state, local law, ordinance, or regulation and will not be discriminated against on these bases. Agilent Technologies, Inc., is committed to creating and maintaining an inclusive in the workplace where everyone is welcome, and strives to support candidates with disabilities. If you have a disability and need assistance with any part of the application or interview process or have questions about workplace accessibility, please email job_******************* or contact ***************. For more information about equal employment opportunity protections, please visit *************************************** Required: NoShift: DayDuration: No End DateJob Function: R&D

Who We Are BioMarin is a global biotechnology company that relentlessly pursues bold science to translate genetic discoveries into new medicines that advance the future of human health. Since our founding in 1997, we have applied our scientific expertise in understanding the underlying causes of genetic conditions to create transformative medicines, using a number of treatment modalities. Using our unparalleled expertise in genetics and molecular biology, we develop medicines for patients with significant unmet medical need. We enlist the best of the best - people with the right technical expertise and a relentless drive to solve real problems - and create an environment that empowers our teams to pursue bold, innovative science. With this distinctive approach to drug discovery, we've produced a diverse pipeline of commercial, clinical and preclinical candidates that have well-understood biology and provide an opportunity to be first-to-market or offer a substantial benefit over existing therapeutic options. About Worldwide Research and Development From research and discovery to post-market clinical development, our WWRD engine involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with genetic diseases. The Enzymes and Metabolic Research group is seeking a highly motivated Scientist II with a strong background in pathology, image analysis and conducting preclinical translational research evaluating potential therapeutics for severe rare genetic diseases with unmet medical needs. Applicants should have experience in basic histologic techniques, immunohistochemical and in situ hybridization assays, imaging and image analysis. Using a quantitative histological approach, this role will design and optimize algorithms to quantify signals detected using in situ hybridization, immunohistochemistry or spatial proteomic and transcriptomic approaches. In addition, this position will evaluate and implement new platform technologies. The ideal candidate is highly motivated, tech savvy, a critical thinker, and able to work both independently as well as in a team environment. In addition, the candidate should possess excellent analytical, organizational and communication skills. Key Responsibilities: * Strong understanding and hands-on experience of histological techniques, including but not limited to, immunohistochemistry, in situ hybridization and spatial transcriptomics. * Advanced microscopy and imaging skills including multiplex fluorescence imaging, confocal microscopy, live-cell imaging, laser capture microdissection, light-sheet microscopy. * Develop novel image analysis algorithms using advanced image analysis software to quantify markers of pathology, subcellur localization and/or biodistribution of novel drug candidates. * Lead or provide functional support for early stage project teams from exploratory through Stage -1. * Author study plans, protocols, technical reports, and SOPs associated with the research design and methods developed to investigate the mechanism of action, efficacy, quality or safety of novel drug candidates. * Collaborate with Business Development on efforts to identify and nominate new assets for investigation and acquisition. * Mentor and coach junior staff on experimental design, troubleshooting, assay optimization and data interpretation. Education: * PhD with a minimum of 3- 5 years related or post-doctoral experience; or a MS and a minimum of 8-10 years related experience; or a BA/BS and a minimum of 8-15 years related experience. * Background in enzyme replacement therapies, lysosomal storage disorders or rare genetic metabolic disease is preferred. Skills and Expertise: * Strong background in analytical pathology, histological techniques, database management and image analysis platforms. * Knowledge of project management tools, methodologies and best practices. * Excellent CRO management, budgeting and resource allocation skills. * Demonstrated ability to work in a fast-paced, team-orientated environment with aggressive timelines. * Ability to interact successfully with team members from a wide variety of functional areas and all levels of contribution and expertise. * Strong communication (verbal and written) skills. Note: This description is not intended to be all-inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned. Equal Opportunity Employer/Veterans/Disabled An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. The salary range for this position is: $116,000 to $159,500. BioMarin considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans. For additional benefits information, visit:

At Gilead, we're creating a healthier world for all people. For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer - working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world's biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead's team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we're looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description As a Gilead intern you will contribute to high-impact meaningful projects that will not only further advance our company's mission but will allow you to gain real world experience at one of the most innovative organizations in the world. You will also have opportunities to participate in special events including professional development and leadership presentations, social/network building activities and local community volunteer programs. Key Responsibilities will include, but are not limited to the following: * Advance our anti-fibrotic portfolio by building novel CRISPR-based tools for the identification of novel targets * Work collaboratively with peers and leadership in the production of meaning scientific discoveries * Produce a scientific summary of your 6-weeks internship by the end of the experience * Network with key individuals at Gilead Sciences to advance your understanding of research in industry and plan your next career move * Showcase your work with a final presentation (PPT) near the conclusion of your internship Your scientific deliverables will be: Establishment of CRISPR lines * To identify the best plasmid delivery methods to generate stable primary fibroblast lines over-expressing CRISPRi and CRISPRa * To produce and stock fibroblast and endothelial primary cell lines with stable integration of CRISPRi and CRISPRa machinery * To characterize lines passage limits and phenotype in comparison with untransformed cells Refine gRNA delivery strategy * Compare gRNA delivery protocols via AAV, lentivirus, plasmid delivery and oligonucleotide based on efficiency of KD and over-expression * Design a small scale screening library for phenotypic screening Required Qualifications: * Must be at least 18 years old * Must have a minimum GPA of 2.8 * Authorized to work in the United States without Sponsorship now or in the future or CPT/OPT through your University. * Must be currently enrolled as a full-time student in a Bachelor's/Masters/MBA/PhD program at an accredited US based university or college * Must be a Rising Sophomore, Junior, or Senior in undergrad or a Graduate or Doctoral Student * Must be enrolled full-time in the Fall Semester at an accredited university/college after the completion of the internship * Must be able to complete a 10-12 consecutive week internship between May and August * Must be able to relocate if necessary and work at the designated site for the duration of the internship Preferred Qualifications: * Preferred Degree qualification: PhD * Proficiency with MS Office Suite * Ability to identify issues and seek solutions * Ability to work both independently and collaboratively * Demonstrated commitment to inclusion and diversity in the workplace * Efficient, organized, and able to handle short timelines in a fast-paced environment Gilead Core Values: * Integrity (Doing What's Right) * Inclusion (Encouraging Diversity) * Teamwork (Working Together) * Excellence (Being Your Best) * Accountability (Taking Personal Responsibility) The expected hourly range for this position is $19.00 - $55.00. Gilead considers a variety of factors when determining base compensation, including education level and geographic location. These considerations mean actual compensation will vary. Benefits include paid company holidays, sick time, and housing stipends for eligible employees. For jobs in the United States: Gilead Sciences Inc. is committed to providing equal employment opportunities to all employees and applicants for employment, and is dedicated to fostering an inclusive work environment comprised of diverse perspectives, backgrounds, and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, sex, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact ApplicantAccommodations@gilead.com for assistance. For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster. NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT Gilead Sciences will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, (c) consistent with the legal duty to furnish information; or (d) otherwise protected by law. Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team. Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion. For Current Gilead Employees and Contractors: Please apply via the Internal Career Opportunities portal in Workday.

At Gilead, we're creating a healthier world for all people. For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer - working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world's biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead's team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we're looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description The Nonclinical Safety department of Gilead Sciences is seeking a motivated and detail-oriented summer intern. This internship offers an opportunity to practice toxicology in a pharmaceutical setting within the Environmental and Occupational Toxicology group, with a focus on data management and hazard assessment. As a Gilead intern you will contribute to high-impact meaningful projects that will not only further advance our company's mission but will allow you to gain real world experience at one of the most innovative organizations in the world. You will also have opportunities to participate in special events including professional development and leadership presentations, social/network building activities and local community volunteer programs. Key Responsibilities will include, but are not limited to the following: * Develop toxicology risk assessments to support manufacturing in areas such as occupational toxicology, impurities, and extractables / leachables * Assist in the development and population of a toxicology-related database to support hazard identification and risk characterization. * Compile and organize toxicological data from internal studies and assessments, and publicly available databases and literature sources. * Support hazard assessments by summarizing key findings from nonclinical studies, including repeat-dose, reproductive/developmental, and chronic toxicity data. * Participate in cross-functional meetings and collaborations with colleagues across departments. * Showcase your work with a final presentation (PPT) near the conclusion of your internship. Required Qualifications: * Must be at least 18 years old * Must have a minimum GPA of 2.8 * Authorized to work in the United States without Sponsorship now or in the future or CPT/OPT through your University. * Must be currently enrolled as a full-time graduate student in a Master's/PhD program in Toxicology, Pharmacology, Biology, Public Health, or a related field at an accredited US based university or college * Must be enrolled full-time in the Fall Semester at an accredited university/college after the completion of the internship * Must be able to complete a 10-12 consecutive week internship between May and August * Must be able to relocate if necessary and work at the designated site for the duration of the internship Preferred Qualifications: * Preferred Degree qualification: Graduate/PhD * Proficiency with MS Office Suite * Ability to identify issues and seek solutions * Ability to work both independently and collaboratively * Demonstrated commitment to inclusion and diversity in the workplace * Efficient, organized, and able to handle short timelines in a fast-paced environment Gilead Core Values: * Integrity (Doing What's Right) * Inclusion (Encouraging Diversity) * Teamwork (Working Together) * Excellence (Being Your Best) * Accountability (Taking Personal Responsibility) The expected hourly range for this position is $19.00 - $55.00. Gilead considers a variety of factors when determining base compensation, including education level and geographic location. These considerations mean actual compensation will vary. Benefits include paid company holidays, sick time, and housing stipends for eligible employees. For jobs in the United States: Gilead Sciences Inc. is committed to providing equal employment opportunities to all employees and applicants for employment, and is dedicated to fostering an inclusive work environment comprised of diverse perspectives, backgrounds, and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, sex, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact ApplicantAccommodations@gilead.com for assistance. For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster. NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT Gilead Sciences will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, (c) consistent with the legal duty to furnish information; or (d) otherwise protected by law. Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team. Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion. For Current Gilead Employees and Contractors: Please apply via the Internal Career Opportunities portal in Workday.

At Gilead, we're creating a healthier world for all people. For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer - working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world's biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead's team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we're looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description As a Gilead intern you will contribute to high-impact meaningful projects that will not only further advance our company's mission but will allow you to gain real world experience at one of the most innovative organizations in the world. You will also have opportunities to participate in special events including professional development and leadership presentations, social/network building activities and local community volunteer programs. Key Responsibilities will include, but are not limited to the following: * Design and optimize enzyme assays using biochemical and analytical techniques. * Perform kinetic studies to determine enzyme parameters (e.g., Km, Vmax). * Analyze and interpret experimental data using appropriate software tools. * Collaborate with scientists across DMPK and related departments. * Present findings in departmental meetings and prepare a final report. * Showcase your work with a final presentation (PPT) near the conclusion of your internship Required Qualifications: * Must be at least 18 years old * Must have a minimum GPA of 2.8 * Authorized to work in the United States without Sponsorship now or in the future or CPT/OPT through your University. * Must be currently enrolled as a full-time student in a Bachelor's/Masters/MBA/PhD program at an accredited US based university or college * Must be a Rising Sophomore, Junior, or Senior in undergrad or a Graduate or Doctoral Student * Must be enrolled full-time in the Fall Semester at an accredited university/college after the completion of the internship * Must be able to complete a 10-12 consecutive week internship between May and August * Must be able to relocate if necessary and work at the designated site for the duration of the internship Preferred Qualifications: * Preferred Degree qualification: Undergrad/Graduate/MBA/PhD/PharmD * Strong understanding of enzymology and enzyme kinetics. * Hands-on experience with biochemical assays and analytical instrumentation (e.g., LC-MS/MS) is preferred. * Excellent problem-solving, communication, and organizational skills. * Ability to work independently and as part of a team * Proficiency with MS Office Suite * Ability to identify issues and seek solutions * Ability to work both independently and collaboratively * Demonstrated commitment to inclusion and diversity in the workplace * Efficient, organized, and able to handle short timelines in a fast-paced environment Gilead Core Values: * Integrity (Doing What's Right) * Inclusion (Encouraging Diversity) * Teamwork (Working Together) * Excellence (Being Your Best) * Accountability (Taking Personal Responsibility) The expected hourly range for this position is $19.00 - $55.00. Gilead considers a variety of factors when determining base compensation, including education level and geographic location. These considerations mean actual compensation will vary. Benefits include paid company holidays, sick time, and housing stipends for eligible employees. For jobs in the United States: Gilead Sciences Inc. is committed to providing equal employment opportunities to all employees and applicants for employment, and is dedicated to fostering an inclusive work environment comprised of diverse perspectives, backgrounds, and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, sex, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact ApplicantAccommodations@gilead.com for assistance. For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster. NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT Gilead Sciences will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, (c) consistent with the legal duty to furnish information; or (d) otherwise protected by law. Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team. Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion. For Current Gilead Employees and Contractors: Please apply via the Internal Career Opportunities portal in Workday.

At Gilead, we're creating a healthier world for all people. For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer - working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world's biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead's team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we're looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description Undergraduate Intern - Research - Virology As a Gilead intern you will contribute to high-impact meaningful projects that will not only further advance our company's mission but will allow you to gain real world experience at one of the most innovative organizations in the world. You will also have opportunities to participate in special events including professional development and leadership presentations, social/network building activities and local community volunteer programs. Key Responsibilities will include, but are not limited to the following: * Support preclinical development and discovery of novel therapeutics targeting infectious diseases * Perform lab-based experiments * Collect and analyze data, interpret results, and draw data-driven conclusions to inform future actions * Participate in team meetings and contribute to collaborative efforts * Document research findings and maintain experimental records regularly * Showcase your work with a final presentation (PPT) near the conclusion of your internship Required Qualifications: * Must be at least 18 years old * Must have a minimum GPA of 2.8 * Authorized to work in the United States without Sponsorship now or in the future or CPT/OPT through your University. * Must be currently enrolled as a full-time student in a Bachelor's/Masters/MBA/PhD program at an accredited US based university or college * Must be a Rising Sophomore, Junior, or Senior in undergrad or a Graduate or Doctoral Student * Must be enrolled full-time in the Fall Semester at an accredited university/college after the completion of the internship * Must be able to complete a 10-12 consecutive week internship between May and August * Must be able to relocate if necessary and work at the designated site for the duration of the internship Preferred Qualifications: * Preferred Degree qualification: Undergrade * Strong background in cellular and molecular biology, virology, or related fields * Proficient in cell culture & molecular cloning techniques * Strong communication and presentation skills * Proficiency with MS Office Suite * Ability to identify issues and seek solutions * Ability to work both independently and collaboratively * Demonstrated commitment to inclusion and diversity in the workplace * Efficient, organized, and able to handle short timelines in a fast-paced environment Gilead Core Values: * Integrity (Doing What's Right) * Inclusion (Encouraging Diversity) * Teamwork (Working Together) * Excellence (Being Your Best) * Accountability (Taking Personal Responsibility) The expected hourly range for this position is $19.00 - $55.00. Gilead considers a variety of factors when determining base compensation, including education level and geographic location. These considerations mean actual compensation will vary. Benefits include paid company holidays, sick time, and housing stipends for eligible employees. For jobs in the United States: Gilead Sciences Inc. is committed to providing equal employment opportunities to all employees and applicants for employment, and is dedicated to fostering an inclusive work environment comprised of diverse perspectives, backgrounds, and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, sex, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact ApplicantAccommodations@gilead.com for assistance. For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster. NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT Gilead Sciences will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, (c) consistent with the legal duty to furnish information; or (d) otherwise protected by law. Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team. Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion. For Current Gilead Employees and Contractors: Please apply via the Internal Career Opportunities portal in Workday.

At Gilead, we're creating a healthier world for all people. For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer - working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world's biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead's team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we're looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description Intern - Research - Inflammation As a Gilead intern you will contribute to high-impact meaningful projects that will not only further advance our company's mission but will allow you to gain real world experience at one of the most innovative organizations in the world. You will also have opportunities to participate in special events including professional development and leadership presentations, social/network building activities and local community volunteer programs. Key Responsibilities will include, but are not limited to the following: * Perform and design in vitro biology experiments to study the immune regulation * Learn and execute novel biological technologies including cell culture and biochemical assays * Review and interpret published work to guide your research. * Interface with cross-functional project team members and participate in scientific presentation Required Qualifications: * Must be at least 18 years old * Must have a minimum GPA of 2.8 * Authorized to work in the United States without Sponsorship now or in the future or CPT/OPT through your University. * Must be currently enrolled as a full-time student in a Bachelor's/Masters/MBA/PhD program at an accredited US based university or college * Must be a Rising Sophomore, Junior, or Senior in undergrad or a Graduate or Doctoral Student * Must be enrolled full-time in the Fall Semester at an accredited university/college after the completion of the internship * Must be able to complete a 10-12 consecutive week internship between May and August * Must be able to relocate if necessary and work at the designated site for the duration of the internship Preferred Qualifications: * Preferred Degree qualification: Undergrad/Graduate/MBA/PhD/PharmD * Proficiency with MS Office Suite * Ability to identify issues and seek solutions * Ability to work both independently and collaboratively * Demonstrated commitment to inclusion and diversity in the workplace * Efficient, organized, and able to handle short timelines in a fast-paced environment Gilead Core Values: * Integrity (Doing What's Right) * Inclusion (Encouraging Diversity) * Teamwork (Working Together) * Excellence (Being Your Best) * Accountability (Taking Personal Responsibility) The expected hourly range for this position is $19.00 - $55.00. Gilead considers a variety of factors when determining base compensation, including education level and geographic location. These considerations mean actual compensation will vary. Benefits include paid company holidays, sick time, and housing stipends for eligible employees. For jobs in the United States: Gilead Sciences Inc. is committed to providing equal employment opportunities to all employees and applicants for employment, and is dedicated to fostering an inclusive work environment comprised of diverse perspectives, backgrounds, and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, sex, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact ApplicantAccommodations@gilead.com for assistance. For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster. NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT Gilead Sciences will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, (c) consistent with the legal duty to furnish information; or (d) otherwise protected by law. Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team. Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion. For Current Gilead Employees and Contractors: Please apply via the Internal Career Opportunities portal in Workday.

At Gilead, we're creating a healthier world for all people. For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer - working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world's biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead's team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we're looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. **Job Description** As a Gilead intern you will contribute to high-impact meaningful projects that will not only further advance our company's mission but will allow you to gain real world experience at one of the most innovative organizations in the world. You will also have opportunities to participate in special events including professional development and leadership presentations, social/network building activities and local community volunteer programs. **Key Responsibilities will include, but are not limited to the following:** + Design and optimize enzyme assays using biochemical and analytical techniques. + Perform kinetic studies to determine enzyme parameters (e.g., Km, Vmax). + Analyze and interpret experimental data using appropriate software tools. + Collaborate with scientists across DMPK and related departments. + Present findings in departmental meetings and prepare a final report. + Showcase your work with a final presentation (PPT) near the conclusion of your internship **Required Qualifications:** + Must be at least 18 years old + Must have a minimum GPA of 2.8 + Authorized to work in the United States without Sponsorship now or in the future or CPT/OPT through your University. + Must be currently enrolled as a full-time student in a Bachelor's/Masters/MBA/PhD program at an accredited US based university or college + Must be a Rising Sophomore, Junior, or Senior in undergrad or a Graduate or Doctoral Student + Must be enrolled full-time in the Fall Semester at an accredited university/college after the completion of the internship + Must be able to complete a 10-12 consecutive week internship between May and August + Must be able to relocate if necessary and work at the designated site for the duration of the internship **Preferred Qualifications** **:** + Preferred Degree qualification: Undergrad/Graduate/MBA/PhD/PharmD + Strong understanding of enzymology and enzyme kinetics. + Hands-on experience with biochemical assays and analytical instrumentation (e.g., LC-MS/MS) is preferred. + Excellent problem-solving, communication, and organizational skills. + Ability to work independently and as part of a team + Proficiency with MS Office Suite + Ability to identify issues and seek solutions + Ability to work both independently and collaboratively + Demonstrated commitment to inclusion and diversity in the workplace + Efficient, organized, and able to handle short timelines in a fast-paced environment **Gilead Core Values:** + Integrity (Doing What's Right) + Inclusion (Encouraging Diversity) + Teamwork (Working Together) + Excellence (Being Your Best) + Accountability (Taking Personal Responsibility) The expected hourly range for this position is $19.00 - $55.00. Gilead considers a variety of factors when determining base compensation, including education level and geographic location. These considerations mean actual compensation will vary. Benefits include paid company holidays, sick time, and housing stipends for eligible employees. **For jobs in the United States:** Gilead Sciences Inc. is committed to providing equal employment opportunities to all employees and applicants for employment, and is dedicated to fostering an inclusive work environment comprised of diverse perspectives, backgrounds, and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, sex, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact ApplicantAccommodations@gilead.com for assistance. For more information about equal employment opportunity protections, please view the 'Know Your Rights' (********************************************** poster. NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT (********************************************************* YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT Gilead Sciences will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, (c) consistent with the legal duty to furnish information; or (d) otherwise protected by law. Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team. Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion. **For Current Gilead Employees and Contractors:** Please apply via the Internal Career Opportunities portal in Workday. Gilead Sciences, Inc. is a biopharmaceutical company that has pursued and achieved breakthroughs in medicine for more than three decades, with the goal of creating a healthier world for all people. The company is committed to advancing innovative medicines to prevent and treat life-threatening diseases, including HIV, viral hepatitis and cancer. Gilead operates in more than 35 countries worldwide, with headquarters in Foster City, California.

Who We Are For more than two decades, going our own way has led to countless breakthroughs, bettering the lives of those suffering from rare genetic disease. In 1997 we were founded to make a big difference in small patient populations. Now we seek to make an even greater impact by applying the same science-driven, patient-forward approach that propelled our last 25 years of drug development to larger genetic disorders, as well as genetic subsets of more common conditions. Through our unparalleled expertise in genetics, drug discovery and development, we will continue to develop targeted therapies that address the root cause of the conditions we seek to treat. Applying our knowledge to make a transformative impact is not just a calling, but an obligation to those who will benefit most. The end goal has always been better lives and now we can reach more people in need. Our Culture Our desire to make a positive impact on our patients extends to our employees and BioMarin is committed to fostering an inclusive environment where every person feels seen, valued, and heard - so employees can thrive in all areas of their lives, in and outside of work. We seek to provide an open, flexible, and friendly work environment to empower people and to provide them with the ability to develop their long-term careers. Ultimately, we want to be an organization where people enjoy coming to work and take pride in our efforts to help patients. BioMarin's Research & Development group is responsible for everything from research and discovery to post-market clinical development. Research & Development involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class or best-in-class therapeutics that provide meaningful advances to patients. Come join our team and make a meaningful impact on patients' lives. Position Overview: We are seeking a motivated Research Associate I with in vivo experience to join the Skeletal and CNP Therapeutic Area group in vivo team to design and execute key studies to transform the lives of people with rare musculoskeletal diseases. The primary role of the Research Associate I will be assisting with the execution of in vivo studies as part of the in vivo team. They will work collaboratively across Research group in the Skeletal and CNP Therapeutic Area group as well as othertherapeutic areas as needed to execute project strategies for in vivo testing of novel therapeutics. The successful candidate will have a background in animal handling, in vivo techniques and demonstrated experience in the use of animal model systems in research. Experience with rodent in vivo models of disease and a collaborative mindset is highly preferred. Experience with skeletal disease biology is desirable. While some industry experience is a plus, it is not required. The successful candidate will contribute to in vivo model evaluation and project teams that support the project goals. Strong written communication skills are critical for IACUC protocols, communicating studyresults, monitoring in vivo studies and tissue collection, and sample management. The successful candidate will have experience with multiple methods of dosing techniques (IM, IP, IV, SC, PO), Necropsy, tissue collection and preferred experience with other in vivo analytic techniques including gait analysis, mechanical evaluation of bone, histology, computerized tomographyand IVIS imaging. The ideal candidate will have a Bachelor's or equivalent scientific degree in Biology or related science. The ideal candidate will have hands-on experience with dosing and data collection in animal models of disease, a proven track record of high-quality science, proficiency with in vivomethods such as administration of test articles, perfusion and tissue collection, blood collection, with rodentsurgical experience preferred. Responsibilities: Support Research Program * Conduct in vivo dosing support and execution of studies including IV, IM, SC, IP, and PO dosing forresearch on genetic skeletal diseases and CNP therapeutic indications * Contribute to novel therapeutic programs based on innovative, ground-breaking discoveries that could lead to new, high-impact opportunities for patients * Participate and collaborate in writing, review and contribution to study synopses, protocols, study reports and regulatory documents * Collaborate with various BioMarin functions to collaboratively ensure timely progression of projects * Excellent written and verbal communication * Ability to build and foster productive cross-functional collaborations both within and external to BioMarin * Execute hands-on responsibilities including but not limited to animal handling and restraint (rodents), administration via various routes of administration, including intravenous (tail-vein), in-life animal health monitoring and measurements, clinical observations, sample collection and processing, and accurate data collection. In addition, providing daily care and monitoring of mice or rats, including health checks and documentation, will also be required. * Follow all institutional, local, and federal regulations regarding animal care and use. Adhere to safety protocols and maintain a clean and organized work environment. Maintain detailed and accurate records of all procedures and animal health status including adverse study events. Meticulous electronic lab notebook documentation. * Communicate experimental plans and results to the project team. Support product development and regulatory filings for pivotal preclinical studies. * Follow instructions and work independently to effectively manage time and prioritize tasks to ensure allassignments are completed on or before deadlines. * Share your knowledge and understanding with other team members * Document experimental methods and outcomes using Electronic Lab Notebooks and generation/maintenance of technical procedure documents and SOPs. * Willingness to work on site full time including off hours and weekends based on study needs. General requirements for the position: * Strong analytical, problem-solving, and decision-making skills * Understanding of genetically engineered models, breeding of rodents * Excellent oral and written communication skills * Passion for contributing your scientific skills to develop therapies for patients in need * Must be able to utilize computer databases for data analysis, data entry, and point of care observations * Must be able to work under time constraints with minimal direction of day-to-day responsibilities, including collaboratively working with multidisciplinary teams * Must be able to work with external regulatory agencies and accreditation groups * Some "off-core business hours" work required * Complete all company training requirements * Perform all work per designated safety standards and comply with Personal Protective Equipment requirements and occupational health to perform work tasks * This position is an on-site critical required position Education and Experience Requirements: * Bachelor's degree in a related subject area or equivalent amount of previous related experience in in vivo study execution * Hands-on experience with animal handling preferred if inclusive of rodent in vivo work. * RA 1 will typically have a minimum of 2 years relevant experience This position is full-time on-site and based in Petaluma, CA with occasional work on site in San Rafael, CA Note: This description is not intended to be all-inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned. Equal Opportunity Employer/Veterans/Disabled An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. The salary range for this position is: $72,000 to $99,000. BioMarin considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans. For additional benefits information, visit:

Who We Are BioMarin is a global biotechnology company that relentlessly pursues bold science to translate genetic discoveries into new medicines that advance the future of human health. Since our founding in 1997, we have applied our scientific expertise in understanding the underlying causes of genetic conditions to create transformative medicines, using a number of treatment modalities. Using our unparalleled expertise in genetics and molecular biology, we develop medicines for patients with significant unmet medical need. We enlist the best of the best - people with the right technical expertise and a relentless drive to solve real problems - and create an environment that empowers our teams to pursue bold, innovative science. With this distinctive approach to drug discovery, we've produced a diverse pipeline of commercial, clinical and preclinical candidates that have well-understood biology and provide an opportunity to be first-to-market or offer a substantial benefit over existing therapeutic options. About Worldwide Research and Development From research and discovery to post-market clinical development, our WWRD engine involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with genetic diseases. The Enzymes and Metabolic Research group is seeking a highly motivated Scientist II with a strong background in pathology, image analysis and conducting preclinical translational research evaluating potential therapeutics for severe rare genetic diseases with unmet medical needs. Applicants should have experience in basic histologic techniques, immunohistochemical and in situ hybridization assays, imaging and image analysis. Using a quantitative histological approach, this role will design and optimize algorithms to quantify signals detected using in situ hybridization, immunohistochemistry or spatial proteomic and transcriptomic approaches. In addition, this position will evaluate and implement new platform technologies. The ideal candidate is highly motivated, tech savvy, a critical thinker, and able to work both independently as well as in a team environment. In addition, the candidate should possess excellent analytical, organizational and communication skills. Key Responsibilities: Strong understanding and hands-on experience of histological techniques, including but not limited to, immunohistochemistry, in situ hybridization and spatial transcriptomics. Advanced microscopy and imaging skills including multiplex fluorescence imaging, confocal microscopy, live-cell imaging, laser capture microdissection, light-sheet microscopy. Develop novel image analysis algorithms using advanced image analysis software to quantify markers of pathology, subcellur localization and/or biodistribution of novel drug candidates. Lead or provide functional support for early stage project teams from exploratory through Stage -1. Author study plans, protocols, technical reports, and SOPs associated with the research design and methods developed to investigate the mechanism of action, efficacy, quality or safety of novel drug candidates. Collaborate with Business Development on efforts to identify and nominate new assets for investigation and acquisition. Mentor and coach junior staff on experimental design, troubleshooting, assay optimization and data interpretation. Education: PhD with a minimum of 3- 5 years related or post-doctoral experience; or a MS and a minimum of 8-10 years related experience; or a BA/BS and a minimum of 8-15 years related experience. Background in enzyme replacement therapies, lysosomal storage disorders or rare genetic metabolic disease is preferred. Skills and Expertise: Strong background in analytical pathology, histological techniques, database management and image analysis platforms. Knowledge of project management tools, methodologies and best practices. Excellent CRO management, budgeting and resource allocation skills. Demonstrated ability to work in a fast-paced, team-orientated environment with aggressive timelines. Ability to interact successfully with team members from a wide variety of functional areas and all levels of contribution and expertise. Strong communication (verbal and written) skills. Note: This description is not intended to be all-inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned. Equal Opportunity Employer/Veterans/Disabled An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

Who We Are BioMarin is a global biotechnology company that relentlessly pursues bold science to translate genetic discoveries into new medicines that advance the future of human health. Since our founding in 1997, we have applied our scientific expertise in understanding the underlying causes of genetic conditions to create transformative medicines, using a number of treatment modalities. Using our unparalleled expertise in genetics and molecular biology, we develop medicines for patients with significant unmet medical need. We enlist the best of the best - people with the right technical expertise and a relentless drive to solve real problems - and create an environment that empowers our teams to pursue bold, innovative science. With this distinctive approach to drug discovery, we've produced a diverse pipeline of commercial, clinical and preclinical candidates that have well-understood biology and provide an opportunity to be first-to-market or offer a substantial benefit over existing therapeutic options. About Worldwide Research and Development From research and discovery to post-market clinical development, our WWRD engine involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with genetic diseases. SUMMARY: The BioMarin Summer Internship Program will enable students to gain valuable experience and knowledge of the processes and systems within BioMarin, while gaining an insight into the pharmaceutical/biotech industry. Over the course of 10 - 12 weeks our interns gain industry experience while working alongside our talented team on meaningful projects. BioMarin's Research and Early Development (RED) team focuses on discovering and advancing innovative therapies for rare genetic conditions. We work across multiple scientific disciplines to translate early research into potential treatments that can make a meaningful impact for patients. The Skeletal Therapeutic Area is dedicated to developing therapies aimed at improving outcomes for individuals with skeletal conditions. Interns will gain exposure to research techniques, contribute meaningful work to support active research programs, and learn how early-stage drug development happens in a collaborative environment. JOB DESCRIPTION/PROJECT: Develop reporter cell lines to monitor gene regulation in response to treatments that alter signaling pathways. Incorporate clinically relevant genetic variants into these models to study their impact on RNA processing and stability, including evaluation of cellular RNA quality-control mechanisms. Required Skills: * Hands-on experience working in a mammalian cell culture lab, including aseptic techniques * Basic understanding of RNA biology * Ability to follow protocols and standard operating procedures with precision * Strong organizational skills and commitment to accurate record-keeping * A proactive, collaborative attitude with a willingness to learn new scientific techniques Desired Skills: * Experience with qPCR or dd PCR for gene expression analysis * Familiarity with Western blot or ELISA for protein-level studies * Ability to analyze and visualize data using graphing or statistical software Qualifications/Eligibility: * Undergraduate student in their 3rd or 4th year pursuing a degree in a scientific discipline. * Must be returning to school in the Fall Term OR has graduated within the 1 year of the start of the program. * Must be available to work full time, 40 hours a week. * Must be currently enrolled as a full-time student at an accredited U.S. based university or college and enrolled in the fall term after the completion of the internship OR have graduated within 1 year of the start of the program. * Must be able to relocate if necessary and work at the designated site for the duration of the internship for on-site, hybrid roles. Benefits of a BioMarin Internship: * Paid hourly wage, paid company holidays, and sick time * Apply skills and knowledge learned in the classroom to on-the-job experiences * Comprehensive, value-added project(s) * Develop skills specific to your major. * Opportunities for professional development by building relationships and learning about other parts of the business. * Participate in company all hands meetings, monthly community lunches * Corporate office amenities such as: 24/7 on-site gym, coffee truck, snacks * Access to Employee Resource Groups Note: This description is not intended to be all-inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned. Equal Opportunity Employer/Veterans/Disabled An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. In the U.S., the salary range for this position is

Career CategoryScientificJob DescriptionJoin Amgen's Mission of Serving Patients At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do. Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas -Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Scientist - Inflammation Research What you will do Let's do this. Let's change the world. In this vital role you will contribute to understanding mechanisms of immune and inflammatory diseases and support the development of novel therapeutic approaches Design, execute, and analyze experiments to explore pathways relevant to inflammatory diseases. Develop and optimize in vitro and ex vivo assays to assess immune cell function, cytokine signaling, and inflammatory responses. Interpret data, draw scientific conclusions, and present findings to project teams and stakeholders. Collaborate with cross-functional teams including translational sciences, clinical, and bioinformatics. Maintain accurate experimental records and contribute to publications, patents, and internal reports. Stay current with scientific literature and emerging technologies in immunology and inflammation research. What we expect of you We are all different, yet we all use our unique contributions to serve patients. The qualified professional we seek is a Scientist with these qualifications. Basic Qualifications: Doctorate degree OR Master's degree & 2 years of scientific experience OR Bachelor's degree & 4 years of scientific experience AND Strong verbal and written communication skills. Ability to collaborate and troubleshoot to solve problems Preferred Qualifications: PhD or MD, with postdoctoral research experience in the fields of immunology, cell biology or molecular biology. Technical expertise in one or more of the following areas: Multi-color flow cytometry, CRISPR/CAS9 technologies, omics data analysis, complex in vitro primary cell models, cell signaling/biochemistry, in vivo mouse models of autoimmune disease, genetics of human disease Demonstrated track record of independent critical thinking and scientific achievement in the area of immunology as demonstrated by high impact publications What you can expect from us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we'll support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans Flexible work models, including remote and hybrid work arrangements, where possible Apply now and make a lasting impact with the Amgen team. careers.amgen.com In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance. Salary Range 129,926.00 USD - 154,420.00 USD

Who We Are For more than two decades, going our own way has led to countless breakthroughs, bettering the lives of those suffering from rare genetic disease. In 1997 we were founded to make a big difference in small patient populations. Now we seek to make an even greater impact by applying the same science-driven, patient-forward approach that propelled our last 25 years of drug development to larger genetic disorders, as well as genetic subsets of more common conditions. Through our unparalleled expertise in genetics, drug discovery and development, we will continue to develop targeted therapies that address the root cause of the conditions we seek to treat. Applying our knowledge to make a transformative impact is not just a calling, but an obligation to those who will benefit most. The end goal has always been better lives and now we can reach more people in need. Our Culture Our desire to make a positive impact on our patients extends to our employees and BioMarin is committed to fostering an inclusive environment where every person feels seen, valued, and heard - so employees can thrive in all areas of their lives, in and outside of work. We seek to provide an open, flexible, and friendly work environment to empower people and to provide them with the ability to develop their long-term careers. Ultimately, we want to be an organization where people enjoy coming to work and take pride in our efforts to help patients. BioMarin's Research & Development group is responsible for everything from research and discovery to post-market clinical development. Research & Development involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class or best-in-class therapeutics that provide meaningful advances to patients. Come join our team and make a meaningful impact on patients' lives. Position Overview: We are seeking a motivated Research Associate I with in vivo experience to join the Skeletal and CNP Therapeutic Area group in vivo team to design and execute key studies to transform the lives of people with rare musculoskeletal diseases. The primary role of the Research Associate I will be assisting with the execution of in vivo studies as part of the in vivo team. They will work collaboratively across Research group in the Skeletal and CNP Therapeutic Area group as well as other therapeutic areas as needed to execute project strategies for in vivo testing of novel therapeutics. The successful candidate will have a background in animal handling, in vivo techniques and demonstrated experience in the use of animal model systems in research. Experience with rodent in vivo models of disease and a collaborative mindset is highly preferred. Experience with skeletal disease biology is desirable. While some industry experience is a plus, it is not required. The successful candidate will contribute to in vivo model evaluation and project teams that support the project goals. Strong written communication skills are critical for IACUC protocols, communicating study results, monitoring in vivo studies and tissue collection, and sample management. The successful candidate will have experience with multiple methods of dosing techniques (IM, IP, IV, SC, PO), Necropsy, tissue collection and preferred experience with other in vivo analytic techniques including gait analysis, mechanical evaluation of bone, histology, computerized tomography and IVIS imaging. The ideal candidate will have a Bachelor's or equivalent scientific degree in Biology or related science. The ideal candidate will have hands-on experience with dosing and data collection in animal models of disease, a proven track record of high-quality science, proficiency with in vivo methods such as administration of test articles, perfusion and tissue collection, blood collection, with rodent surgical experience preferred. Responsibilities: Support Research Program • Conduct in vivo dosing support and execution of studies including IV, IM, SC, IP, and PO dosing for research on genetic skeletal diseases and CNP therapeutic indications • Contribute to novel therapeutic programs based on innovative, ground-breaking discoveries that could lead to new, high-impact opportunities for patients • Participate and collaborate in writing, review and contribution to study synopses, protocols, study reports and regulatory documents • Collaborate with various BioMarin functions to collaboratively ensure timely progression of projects • Excellent written and verbal communication • Ability to build and foster productive cross-functional collaborations both within and external to BioMarin • Execute hands-on responsibilities including but not limited to animal handling and restraint (rodents), administration via various routes of administration, including intravenous (tail-vein), in-life animal health monitoring and measurements, clinical observations, sample collection and processing, and accurate data collection. In addition, providing daily care and monitoring of mice or rats, including health checks and documentation, will also be required. • Follow all institutional, local, and federal regulations regarding animal care and use. Adhere to safety protocols and maintain a clean and organized work environment. Maintain detailed and accurate records of all procedures and animal health status including adverse study events. Meticulous electronic lab notebook documentation. • Communicate experimental plans and results to the project team. Support product development and regulatory filings for pivotal preclinical studies. • Follow instructions and work independently to effectively manage time and prioritize tasks to ensure all assignments are completed on or before deadlines. • Share your knowledge and understanding with other team members • Document experimental methods and outcomes using Electronic Lab Notebooks and generation/maintenance of technical procedure documents and SOPs. • Willingness to work on site full time including off hours and weekends based on study needs. General requirements for the position: • Strong analytical, problem-solving, and decision-making skills • Understanding of genetically engineered models, breeding of rodents • Excellent oral and written communication skills • Passion for contributing your scientific skills to develop therapies for patients in need • Must be able to utilize computer databases for data analysis, data entry, and point of care observations • Must be able to work under time constraints with minimal direction of day-to-day responsibilities, including collaboratively working with multidisciplinary teams • Must be able to work with external regulatory agencies and accreditation groups • Some "off-core business hours" work required • Complete all company training requirements • Perform all work per designated safety standards and comply with Personal Protective Equipment requirements and occupational health to perform work tasks • This position is an on-site critical required position Education and Experience Requirements: • Bachelor's degree in a related subject area or equivalent amount of previous related experience in in vivo study execution * Hands-on experience with animal handling preferred if inclusive of rodent in vivo work. * RA 1 will typically have a minimum of 2 years relevant experience This position is full-time on-site and based in Petaluma, CA with occasional work on site in San Rafael, CA Note: This description is not intended to be all-inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned. Equal Opportunity Employer/Veterans/Disabled An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

Who We Are BioMarin is a global biotechnology company that relentlessly pursues bold science to translate genetic discoveries into new medicines that advance the future of human health. Since our founding in 1997, we have applied our scientific expertise in understanding the underlying causes of genetic conditions to create transformative medicines, using a number of treatment modalities. Using our unparalleled expertise in genetics and molecular biology, we develop medicines for patients with significant unmet medical need. We enlist the best of the best - people with the right technical expertise and a relentless drive to solve real problems - and create an environment that empowers our teams to pursue bold, innovative science. With this distinctive approach to drug discovery, we've produced a diverse pipeline of commercial, clinical and preclinical candidates that have well-understood biology and provide an opportunity to be first-to-market or offer a substantial benefit over existing therapeutic options. About Worldwide Research and Development From research and discovery to post-market clinical development, our WWRD engine involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with genetic diseases. Contract role in This role is onsite five days a week in San Rafael, CA* The Research & Early Development (RED) group is responsible for everything from research and discovery to post-market clinical development. RED involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with rare diseases. Summary Description: Gain industry experience and learn various skills to become a well-rounded scientist capable of advancing drug development. The individual will assist senior staff in planning, performing, and documenting laboratory experiments. Primary responsibilities may include general lab duties, buffer preparation, animal tissue processing, analytical pathology techniques including tissue sectioning (microtomy and cryotomy), histologic staining (e.g. H&E & Masson's trichrome), immunohistochemistry, In Situ Hybridization, and brightfield and epifluorescence microscopy. Other responsibilities include qualitative and basic, quantitative image analysis (Visiopharm), and preparation of image data for power points and reports. The ideal candidate will be responsible for performing, and/or supporting the development and optimization of experimental systems. This role conducts lab-based experimentation based on literature protocols, standard operating procedures (SOPs), consulted innovative approaches, and conducts general laboratory maintenance responsibilities. This role performs data analysis with appropriate documentation of all methods used and proper handling of raw data. Experience & Education per level: Research Associate 1: Bachelor's degree and at least 1-2 years of relevant experience Work Environment/Physical Demands: The employee may frequently be required to sit and talk or hear. The employee is occasionally required to stand; walk; use hands to handle or feel; reach with hands and arms; climb or balance; stoop, kneel, crouch, crawl, and smell. The employee must occasionally lift and/or move up to 25 pounds. Specific vision abilities by this job include close vision, depth perception and ability to adjust focus. Wet lab environment. Some toxic chemical use. Occasional foul odors. Candidate must not have any known chemical allergies. Note: This description is not intended to be all-inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned. An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. In the U.S, the salary range for this position is $ 31 to $ 50 per hour. The base pay actually offered will take into account internal equity, and may also vary depending on candidate's geographic region, job-related knowledge, skills, and experience amongst other factors. The salary range for this position is: $31 to $50. BioMarin considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans. For additional benefits information, visit:

Description Who We Are BioMarin is a global biotechnology company that relentlessly pursues bold science to translate genetic discoveries into new medicines that advance the future of human health. Since our founding in 1997, we have applied our scientific expertise in understanding the underlying causes of genetic conditions to create transformative medicines, using a number of treatment modalities. Using our unparalleled expertise in genetics and molecular biology, we develop medicines for patients with significant unmet medical need. We enlist the best of the best - people with the right technical expertise and a relentless drive to solve real problems - and create an environment that empowers our teams to pursue bold, innovative science. With this distinctive approach to drug discovery, we've produced a diverse pipeline of commercial, clinical and preclinical candidates that have well-understood biology and provide an opportunity to be first-to-market or offer a substantial benefit over existing therapeutic options. About Worldwide Research and Development From research and discovery to post-market clinical development, our WWRD engine involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with genetic diseases. SUMMARY: The BioMarin Summer Internship Program will enable students to gain valuable experience and knowledge of the processes and systems within BioMarin, along with exposure to the pharmaceutical and biotech industry. Over the course of 10 - 12 weeks, interns gain industry experience while working alongside our talented team on meaningful projects. This paid internship will be in the Skeletal and CNP Research group, which is part of BioMarin's Research & Early Development department. The SCNP Research group is responsible for the earliest stages of drug development, which includes proposing new drug strategies for diseases of interest and conducting proof of concept laboratory experiments to support that therapeutic strategy. JOB DESCRIPTION/PROJECT: Throughout the summer, this research intern will be exposed to the industry research atmosphere and introduced to a variety of laboratory techniques used to support the drug development process, which may include techniques like cell culture, western blot, microscopy, and PCR. Interest: Student in their 3 rd or 4 th , pursing a Bachelor's Degree (BS) biological sciences Understanding the application of biological techniques to support industry research Drug therapeutic development Theoretical knowledge: Mammalian cell culture RT-qPCR Western blotting Microscopy and cell imaging SDS-PAGE Other molecular biology and biochemical techniques Qualifications/Eligibility: Undergraduate student pursing a degree in life sciences. Must be available to work full-time, 40 hours a week onsite. Must be currently enrolled as a full-time student at an accredited U.S. based university or college and enrolled in the fall term after the completion of the internship OR have graduated within 1 year of the start of the program Must be able to relocate if necessary and work at the designated site for the duration of the internship for on-site, hybrid roles. Benefits of a BioMarin Internship: Paid hourly wage, paid company holidays, and sick time Apply skills and knowledge learned in the classroom to on-the-job experiences Comprehensive, value-added project(s) Develop skills specific to your major. Opportunities for professional development by building relationships and learning about other parts of the business. Participate in company all hands meetings, monthly community lunches Corporate office amenities such as 24/7 on-site gym, coffee truck, snacks Access to Employee Resource Groups Assistance with housing/transportation to help alleviate costs associated with the internship for eligible employees. Note: This description is not intended to be all-inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned. Equal Opportunity Employer/Veterans/Disabled An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. In the U.S., the salary range for this position is $24 to $ 27 per hour, which factors in various geographic regions. The base pay actually offered will take into account internal equity and also may vary depending on the candidate's geographic region, job-related knowledge, skills, and experience among other factors.

Description Who We Are BioMarin is a global biotechnology company that relentlessly pursues bold science to translate genetic discoveries into new medicines that advance the future of human health. Since our founding in 1997, we have applied our scientific expertise in understanding the underlying causes of genetic conditions to create transformative medicines, using a number of treatment modalities. Using our unparalleled expertise in genetics and molecular biology, we develop medicines for patients with significant unmet medical need. We enlist the best of the best - people with the right technical expertise and a relentless drive to solve real problems - and create an environment that empowers our teams to pursue bold, innovative science. With this distinctive approach to drug discovery, we've produced a diverse pipeline of commercial, clinical and preclinical candidates that have well-understood biology and provide an opportunity to be first-to-market or offer a substantial benefit over existing therapeutic options. About Worldwide Research and Development From research and discovery to post-market clinical development, our WWRD engine involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with genetic diseases. SUMMARY:The BioMarin Summer Internship Program will enable students to gain valuable experience and knowledge of the processes and systems within BioMarin, while gaining an insight into the pharmaceutical/biotech industry. Over the course of 10 - 12 weeks our interns gain industry experience while working alongside our talented team on meaningful projects. BioMarin's Research & Development (R&D) group is responsible for everything from research and discovery to post-market clinical development. Research & Development involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class or best-in-class therapeutics that provide meaningful advances to patients. Come join our team and make a meaningful impact on patients' lives. Within R&D, we have an opening for a motivated Summer Intern to join our Skeletal and CNP Therapeutic Area Analytical Group. This internship offers a unique opportunity to gain hands-on experience by working on a laboratory-based project that supports and contributes to drug development. JOB DESCRIPTION/PROJECT: Work closely with a scientist on a dedicated research project Gain practical experience in molecular biology, analytical and biochemical assays Apply laboratory techniques, which may include immunoassays, microscopy, imaging, PCR/qPCR, immunohistochemistry (IHC), immunofluorescence (IF), and other staining techniques Design, conduct, and interpret experiments Present project updates at group meetings and project summary to the broader department at the end of the summer. Responsibilities Conduct bench experiments under the guidance of a scientist mentor Apply techniques such as immunoassays, microscopy and imaging, PCR/qPCR, IHC, IF, and other analytical techniques Maintain detailed records of experimental design, procedures, and results in electronic laboratory notebooks. Participate in group discussions and present project updates, including a final project summary to the broader department at the end of summer. Theoretical knowledge: Microscopy and imaging techniques Immunohistochemistry (IHC), immunofluorescence (IF), and other analytical techniques Mammalian cell culture PCR/qPCR Immunoassays Other molecular and biochemical assays Qualifications/Eligibility: Student pursuing a bachelor's degree in scientific discipline Must be returning to school in the Fall Term OR has graduated within the 1 year of the start of the program. Must be available to work full time, 40 hours a week. Must be currently enrolled as a full-time student at an accredited U.S. based university or college and enrolled in the fall term after the completion of the internship OR have graduated within 1 year of the start of the program. Must be able to relocate if necessary and work at the designated site for the duration of the internship for on-site, hybrid roles. Benefits of a BioMarin Internship: Paid hourly wage, paid company holidays, and sick time Apply skills and knowledge learned in the classroom to on-the-job experiences Comprehensive, value-added project(s) Develop skills specific to your major. Opportunities for professional development by building relationships and learning about other parts of the business. Participate in company all hands meetings, monthly community lunches Corporate office amenities such as: 24/7 on-site gym, coffee truck, snacks Access to Employee Resource Groups Note: This description is not intended to be all-inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned. Equal Opportunity Employer/Veterans/Disabled An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. In the U.S., the salary range for this position is $24 to $27 per hour, which factors in various geographic regions. The base pay actually offered will take into account internal equity and also may vary depending on the candidate's geographic region, job-related knowledge, skills, and experience among other factors.

Who We Are BioMarin is a global biotechnology company that relentlessly pursues bold science to translate genetic discoveries into new medicines that advance the future of human health. Since our founding in 1997, we have applied our scientific expertise in understanding the underlying causes of genetic conditions to create transformative medicines, using a number of treatment modalities. Using our unparalleled expertise in genetics and molecular biology, we develop medicines for patients with significant unmet medical need. We enlist the best of the best - people with the right technical expertise and a relentless drive to solve real problems - and create an environment that empowers our teams to pursue bold, innovative science. With this distinctive approach to drug discovery, we've produced a diverse pipeline of commercial, clinical and preclinical candidates that have well-understood biology and provide an opportunity to be first-to-market or offer a substantial benefit over existing therapeutic options. About Worldwide Research and Development From research and discovery to post-market clinical development, our WWRD engine involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with genetic diseases. Contract role in This role is onsite five days a week in San Rafael, CA*** The Research & Early Development (RED) group is responsible for everything from research and discovery to post-market clinical development. RED involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with rare diseases. Summary Description: Gain industry experience and learn various skills to become a well-rounded scientist capable of advancing drug development. The individual will assist senior staff in planning, performing, and documenting laboratory experiments. Primary responsibilities may include general lab duties, buffer preparation, animal tissue processing, analytical pathology techniques including tissue sectioning (microtomy and cryotomy), histologic staining (e.g. H&E & Masson's trichrome), immunohistochemistry, In Situ Hybridization, and brightfield and epifluorescence microscopy. Other responsibilities include qualitative and basic, quantitative image analysis (Visiopharm), and preparation of image data for power points and reports. The ideal candidate will be responsible for performing, and/or supporting the development and optimization of experimental systems. This role conducts lab-based experimentation based on literature protocols, standard operating procedures (SOPs), consulted innovative approaches, and conducts general laboratory maintenance responsibilities. This role performs data analysis with appropriate documentation of all methods used and proper handling of raw data. Experience & Education per level: Research Associate 1: Bachelor's degree and at least 1-2 years of relevant experience Work Environment/Physical Demands: The employee may frequently be required to sit and talk or hear. The employee is occasionally required to stand; walk; use hands to handle or feel; reach with hands and arms; climb or balance; stoop, kneel, crouch, crawl, and smell. The employee must occasionally lift and/or move up to 25 pounds. Specific vision abilities by this job include close vision, depth perception and ability to adjust focus. Wet lab environment. Some toxic chemical use. Occasional foul odors. Candidate must not have any known chemical allergies. Note: This description is not intended to be all-inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned. An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

Genentech's Translational Medicine - Oncology organization is seeking an enthusiastic and driven intern to join our cutting-edge translational research efforts aimed at advancing therapies for breast cancer. Our teams focus on translating clinical trial insights into a deeper understanding of therapeutic response and resistance, supporting programs across the early and late-stage pipeline. The successful candidate will partner closely with a scientist to lead a laboratory-based project, gaining expertise in experimental techniques essential for target discovery and validation. This internship also offers the unique opportunity to collaborate with a broad network of experts in discovery biology, bioinformatics, and biomarker and clinical science within the highly collaborative community of Genentech Research & Early Development (gRED). This internship position is located in South San Francisco, on-site. The Opportunity Build in vitro models and develop biological assays to demonstrate functional impacts and elucidate mechanisms of action for target triage and prioritization Design and execute lab-based validation experiments by utilizing genetic engineering or pharmacologic perturbation approaches; characterize cells by applicable assays, including but not limited to flow cytometry, western blots, cytokine arrays, multiomics, and emerging cutting-edge methodologies Process and analyze data; interpret results in the context of the broader scientific strategy Participate in team and department meetings, and effectively collaborate with researchers Program Highlights Intensive 12-weeks, full-time (40 hours per week) paid internship. Program start dates are in May /June 2026. A stipend, based on location, will be provided to help alleviate costs associated with the internship. Ownership of challenging and impactful business-critical projects. Work with some of the most talented people in the biotechnology industry. Final presentations of project work to senior leaders. Lead or participate in intern committees to design and coordinate program events and initiatives. Professional & personal development curriculum throughout the program, including networking opportunities, workshops, and panel discussions. Participate in volunteer projects, social events, and team-building activities. Who You Are Required Education You meet one of the following criteria: Must be pursuing a Master's degree (enrolled student). Must have attained a Master's degree. Must be pursuing a PhD (enrolled student). Required Majors: Cell / Molecular / Cancer Biology, Biochemistry, Immunology, Biological Engineering or related disciplines. Required Skills: Hand-on experience of molecular biology and cell biology techniques. Preferred Knowledge, Skills, and Qualifications Excellent communication, collaboration, and interpersonal skills. Complements our culture and the standards that guide our daily behavior & decisions: Integrity, Courage, and Passion. Relocation benefits are not available for this job posting. The expected salary range for this position based on the primary location of California is $40.00-$46.00 per hour. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for paid holiday time off benefits. Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.