Intellia Therapeutics jobs in Cambridge, MA - 142 jobs
Associate Director, Field Excellence and Data Operations
Intellia Therapeutics 4.4
Intellia Therapeutics job in Cambridge, MA
Why Join Intellia?
Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.
Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to excel and succeed together. We believe in the power of curiosity and pushing boundaries. We welcome challenging thoughts and imagination to develop innovative solutions. And we know that patients are counting on us to make the promise a reality, so we must maintain high standards and get it done.
We want all of our people to go beyond what is possible. We aren't constrained by typical end rails, and we aren't out to just “treat” people. We're all in this for something more. We're driven to cure and motivated for change. Just imagine the possibilities of what we can do together.
How You Will Achieve More:
The Associate Director of Field Excellence and Data Operations will support the building and operations of Intellia's broader Commercial data and field support ecosystem. This role sits at the center of technology, business planning and field execution and will report to the Senior Director of Commercial Data and Operations. This role will necessitate close interaction across the enterprise including; IT, Sales, Insights and Analytics, Marketing, Field/Home Office based employees, etc., and a unique blend of technical and people skills and a willingness to learn.
The Associate Director of Field Excellence and Data Operations will support commercial excellence by synthesizing data, influencing decisions and directing sales execution. Experience managing systems like CRM is a plus, but more important is knowing how it achieves commercial objectives. There will be wide exposure within the organization and a broad opportunity to build skills, competencies and a network for career growth. In partnership with IT this role will support the management the commercial data warehouse and adjacent systems that support CRM, Reporting, MDM, data governance etc. and will be well supported by IT. Additionally this role will partner with sales to deliver solutions that support sales execution like Incentive Compensation, Field Sales Reporting, Targeting, etc.
Responsibilities:
Partner with IT and cross functional partners to design and implement a commercial data environment
Develop and maintain Veeva CRM best practices
Manage vendor support for commercial data integration activities
Utilize commercial data sources to provide recommendations and insights
Support data governance and MDM best practices
Coordinate and integrate digital & multi-channel marketing data into a commercial data environment
Support and advance field focused business needs (targeting, alignment, segmentation, call planning)
Support the Incentive Compensation process (design and administration)
Serve as a lead for commercial field effectiveness and operational inquiries
Manage territory alignments
Identify enhancements of field platforms including CRM, dashboards and processes geared at providing deeper more actionable insights
Ensure field employees have necessary information, data and insights
About You:
Results-driven self-starter with a strong sense of accountability, performance orientation, and the ability to collaborate effectively across functional teams
Ability to build relationships across internal and external stakeholders
Organized and logical with a high degree of flexibility and adaptability
Ability to operate in a fast-paced, entrepreneurial and collaborative environment with strong interpersonal skills and ability to work positively with others
Bachelor's degree in business, Marketing, Life Sciences, or related fields
7+ years of life science industry or relevant consulting experience
Broad experience across numerous pharmaceutical data sources
Salesforce, data warehouse and data management experience
Field planning and commercial operations experience
Managing of vendor relationships
#LI-SV1
#LI-Hybrid
Covid-19 Vaccination Policy:
All Intellia employees, regardless of work location, are expected to follow all applicable federal, state, and local public health regulations and guidelines, and are strongly encouraged to follow all public health recommendations, including being vaccinated for COVID-19.
EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Applications are accepted on a rolling basis, and will continue to be accepted until the position is filled at which point the position will be taken down.
The base salary for this position is expected to range between $189,000.00 - $231,000.00 USD per year.
The salary offered is determined based on a range of factors including, but not limited to, relevant education and training, overall related experience, specialized, rare or in-demand skill sets, internal comparators and other business needs. Upon joining Intellia, your salary will be reviewed periodically and additional factors such as time in role and performance will be considered. Intellia may change the published salary range based on company and market factors.
Additional compensation includes a performance-based annual cash bonus, a new hire equity grant, and eligibility to be considered for annual equity awards the value of which are determined annually at the Company's discretion.
For more information about Intellia's benefits, please click here.
$189k-231k yearly Auto-Apply 60d+ ago
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Senior Corporate Counsel, Commercial
Intellia Therapeutics 4.4
Intellia Therapeutics job in Cambridge, MA
Why Join Intellia?
Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.
Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to excel and succeed together. We believe in the power of curiosity and pushing boundaries. We welcome challenging thoughts and imagination to develop innovative solutions. And we know that patients are counting on us to make the promise a reality, so we must maintain high standards and get it done.
We want all of our people to go beyond what is possible. We aren't constrained by typical end rails, and we aren't out to just “treat” people. We're all in this for something more. We're driven to cure and motivated for change. Just imagine the possibilities of what we can do together.
The Senior Corporate Counsel, Commercial, is accountable for providing legal support to Intellia's Commercial and Medical Affairs groups at a strategic and operational level for the launch of Intellia's first product, a gene editing therapy in Phase 3 development for hereditary angioedema (HAE). The role requires strategic thinking and excellent execution. The position is diverse and demanding, requiring a broad range of experience and a desire to provide legal counsel across a growing and fast-paced organization.
Duties/Responsibilities
The Senior Corporate Counsel will provide primary legal support for the launch of Intellia's first product by working closely with leadership teams and other employees on all aspects of the commercial business.
The Senior Corporate Counsel provides timely and strategic counsel to the program and launch teams on strategic and tactical initiatives with respect to relevant legal and regulatory requirements, including, for example, patient support programs, market access activities, advisory boards, patient ambassadors, speaker programs, and market research.
The Senior Corporate Counsel identifies issues and collaborates with colleagues of all levels to find solutions to critical problems early in the strategic development process, and reviews strategic and tactical plans and various medical, promotional, and educational materials.
The Senior Corporate Counsel serves on various Intellia committees, including the medical, access, commercial committee (MAC); commercial, medical, legal regulatory committee (C-MLR); grants and sponsorships committee (GSC); and medical review committee (MRC).
The Senior Corporate Counsel plays an integral role in enhancing Intellia's compliance program, including drafting and implementing policies, preparing and delivering trainings, and preparing monitoring plans.
As part of a growing business, the Senior Corporate Counsel will have the opportunity for a diverse workload with support of other business activities.
The Senior Corporate Counsel will work with all levels of employees, including senior management. This role requires experience, good judgment and flexibility in a highly-regulated and compliant business. This role provides the opportunity for visibility as a leader in the organization.
Requirements
Skills/Abilities
Knowledge of laws and regulations pertaining to the commercialization of biopharmaceuticals
Knowledge of the biopharmaceutical business and understanding of key commercial activities, including sales and marketing, product distribution, market access, and patient support services
Significant experience with business counseling, and promotional and medical materials review (both pre-launch and post-launch)
Established leadership skills, both within business project and process teams and within law departments
Prior experience supporting the commercial organization in small-to-medium-sized biotechnology company
Experience supporting the launch of rare diseases products
Strong communications skills, both verbal and written
Solutions-oriented mindset; cross-functional team player
Exceptional organizational skills and attention to detail
Solid track record of building strong working relationships in a cross-functional matrix environment and working with different personality types
Strong work ethic; positive outlook; commitment to legal and business teams
Collaborative style; team player
Education / Certifications
JD, licensed to practice law in at least one US State
Experience
12+ years practicing law
Minimum of 8 years of relevant experience including regulatory and commercial support
Physical Requirements
Prolonged periods of sitting at a desk and working on a computer
#LI-Hybrid
Covid-19 Vaccination Policy:
All Intellia employees, regardless of work location, are expected to follow all applicable federal, state, and local public health regulations and guidelines, and are strongly encouraged to follow all public health recommendations, including being vaccinated for COVID-19.
EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
The base salary for this position is expected to range between $250,500.00 - $306,200.00 USD per year.
The salary offered is determined based on a range of factors including, but not limited to, relevant education and training, overall related experience, specialized, rare or in-demand skill sets, internal comparators and other business needs. Upon joining Intellia, your salary will be reviewed periodically and additional factors such as time in role and performance will be considered. Intellia may change the published salary range based on company and market factors.
Additional compensation includes a performance-based annual cash bonus, a new hire equity grant, and eligibility to be considered for annual equity awards the value of which are determined annually at the Company's discretion.
For more information about Intellia's benefits, please click here.
$250.5k-306.2k yearly Auto-Apply 60d+ ago
Oncology Imaging & Biomarker Strategy Lead
Regeneron Pharmaceuticals, Inc. 4.9
Boston, MA job
A leading biotechnology firm is seeking a Clinical Imaging Scientific Director for Oncology to lead imaging strategy and execution in clinical trials. The ideal candidate will have a PhD and over 10 years of experience in clinical imaging, particularly in oncology, with significant expertise in PET imaging and regulatory engagement. This role requires collaboration with research teams and overseeing imaging project implementation, contributing significantly to oncology drug development. Comprehensive benefits are offered to eligible employees.
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$104k-139k yearly est. 4d ago
Senior Medical Science Liaison - Nephrology (Missouri/Iowa/Nebraska/ Illinois: South/Central)
Vertex Pharmaceuticals 4.6
Boston, MA job
Senior Medical Science Liaison - Nephrology (Missouri/Iowa/Nebraska/ Illinois: South/Central) page is loaded## Senior Medical Science Liaison - Nephrology (Missouri/Iowa/Nebraska/ Illinois: South/Central)locations: Boston, MAtime type: Full timeposted on: Posted Todayjob requisition id: REQ-26673**Job Description****General Summary:**The Senior Medical Science Liaison (Sr MSL) (Nephrology) for Povetacicept programs. Povetacicept (pove) is an enhanced, dual BAFF/APRIL inhibitor in pivotal development for the treatment of IgA Nephropathy (IgAN).The Sr MSL will serve as a scientific liaison to the medical/academic community and is responsible for establishing and maintaining relationships with Health Care Providers/Professionals (HCPs) to ensure the appropriate dissemination of clinical and scientific information regarding Vertex' compounds in a timely, ethical and stakeholder-focused manner. The Sr MSL will contribute to shaping the medical plan by providing external stakeholders' insights and contribute to the designing and execution of the Medical Affairs strategy and plan. The Sr MSL will engage HCPs in response to scientific educational and research needs with available Vertex resources and provide the latest emerging data in response to specific inquiries, as appropriate.**Key Duties and Responsibilities:*** Develops and fosters effective and trusting relationships with Thought Leaders (TL) and identifies and engages other appropriate HCPs resulting in scientific engagement with a large network of T1D and transplant-team care providers and opinion leaders. Additionally, understands the inter-relationships both within and between academic centers and utilizes this expertise to enhance Thought Leader and HCP engagements* Consistently incorporates all aspects of the SEM (Scientific Engagement Model) into all interactions, enhancing the quality of interactions and overall relationships as assessed by field coaching observations* Independently incorporates the medical plan into interactions and territory planning (i.e. listening priorities) and captures valuable feedback in the CRM system to inform internal stakeholders and assist in shaping the medical strategy* Possesses an in-depth understanding of the utility and functionality of the CRM system/data analytics tools, allowing for the time sensitive capture of interaction details. Uses CRM/Analytics to enhance future TL engagements and manage workload* Discusses scientific information effectively and compliantly with external stakeholders at an advanced level of communication for both disease state and product to external stakeholders as assessed by management coaching and field observations* In-depth conceptual and practical knowledge of payers in the region and possesses an in-depth understanding of the impact of payers on patient care delivery* Assists clinical development/clinical operations by fully understanding IB content and presenting IB material, providing nominations for trial sites as requested, providing end of study data reviews with investigators (as needed)* Represents Vertex at medical congresses by providing scientific session/abstract coverage, booth staffing coverage, routine TL interactions, contributing to the daily and end of congress summaries and may provide logistical guidance through organizing and scheduling abstract/session coverage and preparing and delivering the conference debrief (as needed)* May serve as a mentor or trainer for colleagues with less experience; for example, assisting with new hire MSL onboarding* Conducts all activities in compliance with Vertex policy and procedures and performs all administrative tasks in a timely manner such as CRM entry, vehicle mileage reporting, expense reporting, calendar entries, training assignments, etc.**Knowledge and Skills:*** Ability to complete goals within allotted timeframes, and deliver high quality results* Ability to help plan and complete projects in a constantly changing field-based environment* Ability to appraise and comprehend medical and scientific literature* Ability to effectively present clinical/scientific information in a credible manner in varied settings* Good knowledge of assigned geographic territory* In-depth understanding of healthcare regulatory environment* Apply proficient knowledge of relevant T1D and T1D management protocols, healthcare environment and landscape to articulate the medical and scientific value of our products* Demonstrated working understanding around the compliance and regulatory frameworks that govern the pharmaceutical industry and conducts compliant interactions with internal and external stakeholders.* In-depth knowledge of payers and unique medical information needs to support access and appropriate use of Vertex medicines* Good knowledge of Health Economics and Outcomes Research* Fluent in English (oral and written)**Education and Experience:*** Minimum requirement for advanced biomedical or life sciences degree (ex. Masters, NP, PA)* Requires minimum of 3-4 years of experience as an MSL supporting Nephrology programs or in other medical affairs roles in the pharma/biotech industry or the equivalent combination of education and experience.* Previous training or experience in designated therapeutic area is helpful Pay Range:$171,300 - $245,000Disclosure Statement:The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.**Company Information**Vertex is a global biotechnology company that invests in scientific innovation.Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com.
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$171.3k-245k yearly 4d ago
Nephrology Medical Affairs Leader, Global Strategy
Vertex Pharmaceuticals 4.6
Boston, MA job
A leading biotechnology company is seeking a Senior Director for Global Medical Affairs in Nephrology. This role involves providing medical and scientific leadership, developing medical affairs plans, and ensuring compliance with regulatory standards. A terminal scientific degree and 11 years of relevant experience are required. The position offers a salary range of $240,000 to $360,000, hybrid work arrangements, and various employee benefits including paid time off and educational assistance.
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$69k-94k yearly est. 5d ago
Lead, Downstream Biologics Process Development
Vertex Pharmaceuticals 4.6
Boston, MA job
A global biotechnology company is seeking a Director of Downstream Process Development in Boston. This role requires advanced leadership skills and expertise in biologics, overseeing the development and optimization of therapeutic biologics with responsibilities in both technical and regulatory aspects. Candidates should have extensive experience with chromatography systems and drug substance development, ensuring compliance with quality standards. Competitive salary range is $195,500 - $293,200, and this is an on-site position.
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$195.5k-293.2k yearly 5d ago
Principal Engineer, AI-Driven QC & Data Consumption
Vertex Pharmaceuticals (San Diego) LLC 4.6
Boston, MA job
A leading global biotechnology firm in Boston seeks a Principal Engineer to lead the automation of pre-clinical data pipelines and regulatory reporting solutions. This role focuses on driving modernization and standardization initiatives, leveraging AI technologies, and enhancing data consumption practices. Candidates should possess strong programming skills and a degree in a relevant field, with a minimum of five years in technical leadership within the biotechnology industry. The position offers a hybrid work model and a comprehensive benefits package.
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$105k-132k yearly est. 3d ago
Senior S&OP & Supply Chain Leader (Cell & Gene)
Vertex Pharmaceuticals 4.6
Boston, MA job
A global biotechnology company is seeking a Commercial Supply Chain Associate Director to lead the Sales and Operations Planning for Casgevy. This role involves working effectively with cross-functional teams, establishing key assumptions, and overseeing performance indicators. The ideal candidate will have at least 8 years of experience in supply chain management, preferably within the cell and gene therapy field. This position is eligible for a hybrid work model, offering flexibility in workplace arrangements.
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$104k-132k yearly est. 1d ago
GMP Quality Associate Director - Operations & Compliance
Vertex Pharmaceuticals 4.6
Boston, MA job
A leading biotechnology company in Boston is seeking an Associate Director, GMP Operational Quality to ensure compliance and quality oversight for commercial drug manufacturing. The role includes managing relationships with vendors, mentoring team members, and leading quality improvement initiatives. Candidates should possess strong knowledge of cGMPs, a scientific degree, and extensive experience in quality assurance and project management. This position offers a hybrid work model and competitive compensation package.
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$80k-101k yearly est. 3d ago
Strategic Operations Lead, US Market Access
Vertex Pharmaceuticals 4.6
Boston, MA job
A global biotech company is seeking an Associate Director for Strategy and Operations in Boston. This role supports the US Market Access Leadership Team, driving strategic initiatives and operational execution. The ideal candidate will have over 8 years of experience, strong communication and collaboration skills, and a Bachelor's degree. The position offers a hybrid or on-site work model and competitive compensation ranging from $155,700 to $233,600 annually, with additional benefits such as educational support and paid time off.
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$155.7k-233.6k yearly 1d ago
Senior Accountant
Intellia Therapeutics 4.4
Intellia Therapeutics job in Cambridge, MA
Why Join Intellia?
Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.
Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to excel and succeed together. We believe in the power of curiosity and pushing boundaries. We welcome challenging thoughts and imagination to develop innovative solutions. And we know that patients are counting on us to make the promise a reality, so we must maintain high standards and get it done.
We want all of our people to go beyond what is possible. We aren't constrained by typical end rails, and we aren't out to just “treat” people. We're all in this for something more. We're driven to cure and motivated for change. Just imagine the possibilities of what we can do together.
The Senior Accountant will be a core member of the Accounting team, responsible for the integrity of the General Ledger and the efficiency of the month-end close cycle. This role requires exceptional attention to detail, strong technical accounting competence, and the ability to manage operational accounting processes critical for a transitioning biotech (from R&D to commercial). Experience in a public company environment and familiarity with SOX compliance and ERP systems are essential.
Duties/Responsibilities
Support the full cycle month-end, quarter-end, and year-end close processes, ensuring all financial deadlines are met accurately and efficiently.
Prepare and post complex journal entries across various accounts, including R&D and G&A accruals, prepaid amortization, fixed assets, and others as necessary.
Perform detailed and timely reconciliations of all assigned Balance Sheet accounts, investigating and resolving all discrepancies promptly.
Conduct thorough P&L and Balance Sheet flux analyses, providing clear, documented explanations for variances compared to prior periods
Serve as a key contact for external auditors during quarterly reviews and the annual audit, preparing required supporting schedules and documentation.
Manage the accounting for Fixed Assets and related capital expenditure tracking and tagging, ensuring proper capitalization and disposal procedures are followed.
Ensure all general ledger activities and account reconciliations are performed in compliance with US GAAP.
Maintain and update documentation for internal controls over financial reporting (SOX 404), specifically for general ledger and operational cycles (e.g. fixed assets).
Execute and document periodic testing of assigned SOX controls to ensure operating effectiveness.
Work with R&D employees to adhere to monthly time reporting requirements
Actively participate in the maintenance and optimization of the company's ERP system and other financial tools, focusing on streamlining the close process.
Identify opportunities for automation and efficiency gains within daily and monthly accounting tasks.
Develop and maintain robust, comprehensive standard operating procedures (SOPs) for key responsibilities.
Assist with additional projects, system implementations, integrations, and updgrades
Supervisory Responsibilities
☐ N/A
Requirements
Skills/Abilities
Detail-oriented with high standards for accuracy and data integrity.
Excellent ability to manage competing deadlines and priorities in a fast-paced, dynamic environment.
Strong analytical and problem-solving skills.
Effective written and verbal communication skills to interact across all levels of the organization.
Intellectual curiosity with the ability to problem solve with minimal oversight.
Proficient with Accounting software (e.g. Oracle, FloQast) and advanced Excel skills (e.g. pivot tables, XLOOKUP, etc.)
Education / Certifications
Bachelor's degree in accounting or finance.
Prior experience in a publicly traded company is required.
Certified Public Accountant (CPA) preferred.
Experience in the Biotechnology or Pharmaceutical industry preferred.
Experience in Big 4 accounting firms a plus
Experience
3+ years of progressive experience in accounting/finance experience
Physical Requirements
Prolonged periods of working on a computer
#LI-Hybrid
Covid-19 Vaccination Policy:
All Intellia employees, regardless of work location, are expected to follow all applicable federal, state, and local public health regulations and guidelines, and are strongly encouraged to follow all public health recommendations, including being vaccinated for COVID-19.
EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Applications are accepted on a rolling basis, and will continue to be accepted until the position is filled at which point the position will be taken down.
The base salary for this position is expected to range between $94,500.00 - $115,500.00 USD per year.
The salary offered is determined based on a range of factors including, but not limited to, relevant education and training, overall related experience, specialized, rare or in-demand skill sets, internal comparators and other business needs. Upon joining Intellia, your salary will be reviewed periodically and additional factors such as time in role and performance will be considered. Intellia may change the published salary range based on company and market factors.
Additional compensation includes a performance-based annual cash bonus, a new hire equity grant, and eligibility to be considered for annual equity awards the value of which are determined annually at the Company's discretion.
For more information about Intellia's benefits, please click here.
$94.5k-115.5k yearly Auto-Apply 28d ago
National Strategic Accounts Team Lead
Intellia Therapeutics 4.4
Intellia Therapeutics job in Cambridge, MA
Why Join Intellia?
Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.
Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to excel and succeed together. We believe in the power of curiosity and pushing boundaries. We welcome challenging thoughts and imagination to develop innovative solutions. And we know that patients are counting on us to make the promise a reality, so we must maintain high standards and get it done.
We want all of our people to go beyond what is possible. We aren't constrained by typical end rails, and we aren't out to just “treat” people. We're all in this for something more. We're driven to cure and motivated for change. Just imagine the possibilities of what we can do together.
How You Will Achieve More:
We are seeking an experienced and visionary National Strategic Accounts Team Lead to lead the enablement and optimization of treatment sites delivering our transformative CRISPR therapy to patients. Reporting to the VP of Sales, this role will lead a new team of 6 to 8 strategic account managers who will profile and prioritize treatment sites pre-launch including stakeholder mapping, capability and capacity assessments, and developing care pathways supporting the patient to product journey. Following launch, this role will ensure this team leads treatment pull-through including procurement, delivery, and administration of therapy. The ideal candidate brings a strong background in treatment site activation, cross-functional leadership, and a passion for building infrastructure that supports patient access to one-time therapies.
This is a career-defining opportunity to lead the first-ever commercialization of an in vivo one-time CRISPR based therapy, requiring a leader who can build and inspire high-performing teams while navigating uncharted territory in genetic medicine. The ideal candidate is a strategist with a strong entrepreneurial spirit, collaborative mindset, and a deep commitment to Intellia's core values: One, Explore, Disrupt, and Deliver.
Responsibilities:
Team Leadership & Development
Build, lead, and mentor a high-performing team of Strategic Account Managers focused on activating treatment sites, building operational care pathways, and infusion capabilities to ensure pull-through and administration of Intellia therapies
Establish clear goals, performance metrics, and development plans to support team growth and success.
Foster a culture of collaboration, accountability, and continuous improvement.
Strategic Leadership
Define and drive the strategy for treatment site enablement, ensuring alignment with sales, medical, patient services, marketing, commercial operations, and market access
Develop a roadmap for treatment center activation, operational excellence, and long-term scalability.
Serve as a thought leader and internal advocate for treatment center needs
Cross-Functional Collaboration
Partner with Sales, Medical Affairs, Market Access, Marketing, Commercial Operations, and Patient Services to ensure seamless treatment center activation and support.
Represent the treatment center function in leadership forums and strategic planning discussions.
Partner with commercial leadership to provide updates on performance and site activation
Operational Excellence
Oversee the development and implementation of standardized processes for treatment center profiling, qualification, and training
Monitor treatment center performance and drive continuous improvement in key metrics such as turnaround time, compliance, and capacity utilization.
Ensure adherence to regulatory and quality standards across all treatment center activities.
External Engagement
Build and maintain strong relationships with treatment center leadership, including C-suite, P&T committee members, pharmacy leadership, and revenue cycle managers.
Serve as a senior point of contact for escalations, strategic partnerships, and long-term planning with key institutions.
Represent the company at industry forums, conferences, and working groups related to treatment site readiness and enablement.
Supervisory Responsibilities
Build and lead a new team focused on site and treatment center strategy and operations.
Optimize team structure, roles, and responsibilities to support current and future business needs.
Lead recruitment, onboarding, and development of team members.
Foster a collaborative, inclusive, and high-performance culture that encourages innovation and accountability.
Provide coaching, mentorship, and performance management to ensure team success and professional growth.
About You:
Collaborate with human resources to attract, hire, develop, and motivate top industry talent to ensure the highest performance standards.
Proven track record of successfully partnering cross functionally to build and lead the establishment of a new function and organizational capabilities.
Management and oversight of functional budget and resourcing
Proven track record of introducing novel, impactful approaches that challenge convention and accelerate the delivery of innovative therapies to patients.
Ability to engage with C-Level stakeholders
Project management and cross functional coordination experience
Ability to navigate complex health systems
Experience leading site activation in cell and gene therapy
History of engaging multiple internal and external stakeholders and building strong partnerships with them
Demonstrates outstanding verbal, written, and interpersonal skills with the ability to influence others and build strong relationships across a diverse stakeholder landscape.
Deep understanding of the stakeholder ecosystem within treatment sites including health systems, IDNs, and hospitals
Proven ability to lead teams, manage complex projects, and influence across a matrixed organization.
Experience launching and scaling capabilities for complex, high-cost, buy-and-bill therapies
Results-driven self-starter with a strong sense of accountability, performance orientation, and the ability to collaborate effectively across functional teams.
Organized and logical with a high degree of flexibility and adaptability
Comfortable navigating ambiguity and shifting priorities, with a high degree of flexibility to pivot as needed
Bachelor's degree in life sciences, business, healthcare administration, or related field; advanced degree (MBA, MPH, PharmD) a plus.
10+ years of experience in biotech/pharma, health systems, and treatment site activation for high-cost, buy and bill, HCP administered therapies, with at least 3-5 years in a leadership role.
Ideally, the candidate will have experience with one-time therapies
#LI-SV1
#LI-Remote
Covid-19 Vaccination Policy:
All Intellia employees, regardless of work location, are expected to follow all applicable federal, state, and local public health regulations and guidelines, and are strongly encouraged to follow all public health recommendations, including being vaccinated for COVID-19.
EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Applications are accepted on a rolling basis, and will continue to be accepted until the position is filled at which point the position will be taken down.
The base salary for this position is expected to range between $254,700.00 - $311,300.00 USD per year.
The salary offered is determined based on a range of factors including, but not limited to, relevant education and training, overall related experience, specialized, rare or in-demand skill sets, internal comparators and other business needs. Upon joining Intellia, your salary will be reviewed periodically and additional factors such as time in role and performance will be considered. Intellia may change the published salary range based on company and market factors.
Additional compensation includes a performance-based annual cash bonus, a new hire equity grant, and eligibility to be considered for annual equity awards the value of which are determined annually at the Company's discretion.
For more information about Intellia's benefits, please click here.
$83k-119k yearly est. Auto-Apply 4d ago
Finance Systems & Reporting Excellence Director
Vertex Pharmaceuticals 4.6
Boston, MA job
A leading biotechnology company is seeking a Director, Global Process Excellence to enhance finance systems and processes integral to scaling operations. This role requires extensive finance experience, capability in project management, and leading cross-functional improvements. The position offers a hybrid work model and competitive salary range of $180,800 - $271,100, along with generous benefits and annual bonus eligibility.
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$180.8k-271.1k yearly 4d ago
Vertex Summer 2026 Intern, Preclinical Modeling and Simulation, DMPK
Vertex Pharmaceuticals 4.6
Boston, MA job
Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you'll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We're passionate about innovation, inclusion, and supporting your growth-inside and outside the lab.
Why Vertex?
Real Projects: You'll work on assignments that make a real impact, not just busy work.
Mentorship & Networking: Connect with leaders and peers who want to see you succeed through professional networks, connections, and collaborations that will shape your longer-term career.
Flexible & Supportive: We offer flexible work options with Flex @ Vertex and prioritize your wellbeing.
Inclusive Culture: Collaboration and inclusion are embedded in everything we do.
Career Launchpad: Build skills, explore career paths, and get guidance for your future career.
Ready to apply? Submit your application and let's turn possibilities into reality!
Your Impact
The Vertex Research internship program is a multi-week experiential training program for students currently working towards an advanced degree in Applied Mathematics, Computational Biology, Pharmaceutical Sciences, Chemical Engineering, or a related field of study. If you are passionate, collaborative, and growth-minded, an internship at Vertex will help you gain meaningful experience in our Drug Metabolism Pharmacokinetics functional areas and serve as a launchpad for your career.
Important Notice Regarding Internship and Co-op Inquiries
At Vertex Pharmaceuticals, we are committed to providing a fair and structured recruitment process for all students interested in internship and co-op opportunities. To ensure consistency and equity, all student applications must go through our Early Talent Acquisition Team.
Due to the high volume of interest, we are unable to respond to individual solicitation. Direct solicitation to Vertex employees- including senior leaders via email will result in removal from the recruiting process.
We appreciate your enthusiasm and interest in Vertex. To be considered for internship or co-op roles, please apply directly through our official application channels. (**************************************************************************
Thank you for respecting our process and helping us maintain a fair experience for all candidates.
What you will be doing:
The Preclinical Modeling and Simulation (pM&S) team within the DMPK department uses mathematical models and computational tools to predict, optimize, and quantify the absorption, distribution, metabolism, and excretion of drug candidates. This intern position will work with the pM&S team to develop mechanistic and systems-based models of diseases for translational research purposes.
Develop and implement quantitative systems pharmacology (QSP) models of relevant diseases in collaboration with the pM&S team
Source modeling techniques and approaches from literature sources or design novel models as necessary to address questions and inform decision making across programs
Collect relevant data from published sources as necessary for model calibration
Present and discuss research progress with the pM&S team, DMPK, and other stakeholders as appropriate
What you will need to succeed:
Enrolled in a graduate program, majoring in Applied Mathematics, Computational Biology, Pharmaceutical Sciences, Chemical Engineering, or a related field of study.
Significant experience (2-4 years minimum) using a programming language such as Matlab, Python, R, or Julia to numerically solve systems of ordinary differential equations is required for this position
Experience designing and implementing ordinary differential equation-based models of biological systems, including parameter optimization using time-series data
Experience importing, processing, and visualizing data using one of the programming languages listed above
History of publication and/or conference presentations in mathematical biology, quantitative pharmacology, or QSP
Knowledge of pharmacokinetics (PK), pharmacokinetic-pharmacodynamic (PKPD) modeling, QSP, population pharmacokinetics (pop PK), or graduate coursework in applied mathematics is desirable but not required
Knowledge of modeling softwares commonly used in the pharmaceutical industry such as Phoenix WinNonlin, SimBiology, SimCyp, or MonolixSuite is desirable but not required
Expertise in at least one specific disease area is desirable but not required
Legal authorization to work in the United States, now and in the future. Please note that Vertex does not provide sponsorship for internships or entry level roles within this part of the organization.
You must be enrolled in an advanced degree program if graduating before August 2026
You must be available to work full-time, 40 hours per week from May - August 2026
Program Details:
Full-time, paid internship $26.00 - 35.00 USD/hour
Program Dates: May - August 2026
At Vertex, we believe that when you feel your best, you can perform at your best. That's why our US benefits and global well-being resources are designed to support you.
• Free 24/7 onsite gym access and free access to group exercise classes
• Subsidized commuter benefits- transit and parking
• Provided meals-free breakfast daily!
• Career development opportunities and events, including C Suite engagement
• Social events-both intern-only and company-wide
• Location-specific perks and extras!
• Recognition of National Intern Day
Equal Opportunities
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Vertex is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements.
Accessibility & Accommodations
We're focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best. Vertex is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com.
Export Control Notice
This position may involve access to technology or data that is subject to U.S. export control laws, including the Export Administration Regulations (EAR). As such, employment is contingent upon the applicant's ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements, only individuals who qualify as U.S. persons (citizens, permanent residents, asylees, or refugees) are eligible for this position. For this role, Vertex is unable to sponsor non-U.S. persons to apply for an export control license.
This job posting is for a temporary role with a third-party agency partner that provides services to Vertex. The individual selected for this role will be offered the role as an employee of that third-party agency; compensation, medical benefits, fringe benefits and other terms and conditions of employment shall be presented by the third-party agency upon offer.
For any questions or concerns, please contact early_***************.
Pay Range:
$0 - $0
Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
Hybrid-Eligible Or On-Site Eligible
Flex Eligibility Status:
In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.
#LI-Hybrid
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com
$26-35 hourly Auto-Apply 21d ago
Senior Director, CMC and Manufacturing Data & Technology
Vertex Pharmaceuticals 4.6
Boston, MA job
Vertex is a global biotechnology company that invests in scientific innovation. The Digital, Technology and Engineering (DTE) Research, Pre-Clinical, Manufacturing & Supply (RPMS) Group's mission is to improve the lives of patients through data, and technology innovation - with AI at the core of our transformation strategy.
Vertex is in a transformational period where we are accelerating our capabilities, technology and data to augment our scientific mission and enable Vertex to grow in scale; ensuring we remain on the forefront of science, medicine and technology.
The Senior Director, CMC and Manufacturing Data & Technology will define, lead and execute the vision for how Vertex will revolutionize our global pharmaceutical science and manufacturing activities through AI, data science and technology solutions. You will champion the adoption of AI-driven approaches to optimize manufacturing operations, drive predictive analytics, enable intelligent automation across pharmaceutical development, clinical and commercial manufacture based upon a foundation of robust transactional systems to plan, track and action in internal and external manufacturing facilities.
Working with multiple Vertex business units, the Senior Director is accountable for the end-to-end manufacturing experience worldwide, across a broad range of internal and external pharmaceutical development and manufacturing teams powering both clinical and commercial supply.
The role is a critical part of the Data Technology & Engineering leadership community. The Senior Director will bring their multi-disciplinary expertise to orchestrate innovation with leaders across science, manufacturing, data science and technology, including core disciplines in infrastructure, data and software engineering, data science, architecture, portfolio and security, to ensure coordination as all R&D and Manufacturing environments transform through smart, scalable solutions.
Reporting directly to the VP RPMS, the dynamic and experienced Senior Director, CMC and Manufacturing Data & Technology will play a key role on the RPMS Leadership Team to drive our digital transformation initiatives across Research, Pre-clinical, Manufacturing and Supply Chain.
Key Duties and Responsibilities:
Vision and Strategy
Develops, articulates, and executes a clear vision for delivering AI-powered technology solutions for CMC and manufacturing worldwide, internally and externally, across multiple business units, in alignment with Vertex's strategic goals.
Influences a broad internal and external landscape to cultivate a roadmap of opportunities to transform pharmaceutical development and manufacturing activities through cutting-edge AI technologies including generative and agentic AI, machine learning and data driven automation.
Leads with agility to think strategically about scientific, engineering, business, product, and technical challenges simultaneously.
Collaborates as a trusted partner to the research and manufacturing leadership to ensure technology strategies robustly accelerate portfolio and commercial goals and as key enablers of operational excellence.
Operational Execution
Specializes in driving transformative strategies that foster innovation, elevate organizational performance and drive growth.
Leads in the identification of opportunities for innovation in delivery, evaluation of state-of-the-art AI (including generative AI and agentic AI), data product, data science, external and internal integrations, software, hardware and protocols, applicability and risks.
Combines creativity, practicality and integrity to ensure technology solutions that are strategic, flexible, scalable, reusable and are achieved through the application of Vertex's architectural principles, standards and governance.
Leads with rigor and discipline maximizing fiscal, resource and operational effectiveness.
Manages an effective and efficient technology operation that enhances manufacturing at Vertex, ensuring stakeholders can depend on technology as a robust enabler of drug research and production whilst maximizing ROI.
Partners effectively with suppliers ensuring effective delivery aligned to Vertex's high expectations in compliance, quality and security.
Leadership
Leads and develops a high-performing, diverse team of professionals, fostering a culture of innovation, collaboration, and accountability.
Creates a culture of inclusion, diversity, and equity where everyone can do their best work and feels valued.
Aligns the CMC and manufacturing technology team with enterprise priorities, ensuring data strategies drive business outcomes and regulatory compliance.
Represent the CMC and manufacturing technology technology organization in internal and external forums, advocating for its ability to achieve strategic goals and for innovation leadership.
Required Education and Experience:
Bachelor's degree in science, engineering, computer science or a related field or relevant experience
10+ years of experience in life sciences technology or related fields.
Relevant experience in creating and applying technologies to solve computationally intensive and data intensive problems in manufacturing, inclusive of 5+ years in a leadership role.
Required Knowledge and Skills
Extensive knowledge of large-scale scientific and manufacturing environments to effectively understand user needs.
Extensive technical knowledge and experience across broad range of complex scientific and manufacturing technology.
Extensive experience in applying AI and machine learning to solve complex, data intensive problems in global manufacturing environments.
Extensive experience in core foundational manufacturing operations technology including electronic batch records, process control, execution systems, quality and exception systems.
Strength and depth in leading and overseeing operations technical support for a manufacturing environment.
Experience with varied compute environments including distributed, cloud and high performance computing.
Experience of successfully developing and implementing technology strategy; preferably within a complex pharmaceutical manufacturing organization.
Expertise in successful development and delivery of multiple complex scientific and manufacturing technology development initiatives.
Strong leadership and team-building skills, with demonstrated success in managing diverse teams and fostering high engagement.
Excellent communication skills including the ability to produce strategic documents, present ideas and solutions to technical and non-technical audiences and all levels of the organization.
A strong commitment to compliance and integrity in systems, processes, and actions, with a deep understanding of the biotech regulatory environment.
Exceptional problem-solving and strategic thinking abilities, with a focus on driving innovation and operational excellence.
Other Requirements
Experience with enabling advanced technologies, such as AI and machine learning, through data engineering strategies is highly desirable.
Advanced certifications in product, agile, software engineering, cloud technologies, or leadership.
#LI-Hybrid
Pay Range:
$236,000 - $354,000
Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
Hybrid-Eligible Or On-Site Eligible
Flex Eligibility Status:
In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.
#LI-Hybrid
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com
$236k-354k yearly Auto-Apply 60d ago
Director, US Kidney Digital Marketing - Launch & Growth
Vertex Pharmaceuticals (San Diego) LLC 4.6
Boston, MA job
A leading biotechnology company is seeking a Director of Digital Marketing to drive engagement for their kidney portfolio. You will develop omnichannel strategies, collaborate across teams, and leverage data insights to enhance brand impact. Ideal candidates will have over 10 years in pharmaceutical marketing and proven success in digital campaigns. This position offers a hybrid work option and competitive compensation according to skills and experience, along with extensive benefits.
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$129k-165k yearly est. 4d ago
External Manufacturing Associate Director
Vertex Pharmaceuticals, Inc. 4.6
Boston, MA job
Associate Director, Cell & Gene Therapies External Manufacturing Operations - Commercial Manufacturing & Supply Chain, Vertex Pharmaceuticals (based in US, New England) The primary focus of the Associate Director, External Manufacturing role is to oversee Vertex's critical cell and gene therapy Contract Manufacturing Organizations (CMOs) and implement our vision for this business-critical function. We are looking for a candidate with the breadth of professional experience and the drive to work with both internal and external partners to define and manage the ongoing cGMP supply of cell and gene therapy products from clinical through post-approval lifecycle management. The right candidate should have the ability to understand the challenges and make proactive decisions after anticipating cross-functional and patient impact. The successful candidate should have a strong operational, quality, compliance and technical background, with proven project management and supplier management abilities. The candidate will be located either at the cell and gene therapy CMO's site and/or be able to travel up to 50% of their time to those sites as a "Person-in-Plant" to oversee activities on the ground, and/or as a SME to provide technical support to resolve emerging issues. The successful candidate will be a key member of the Vertex/CMO Virtual Plant Team (VPT) contributing to the broader External Manufacturing group activities.
Key Responsibilities:
* Function as the first/primary point of contact for all Vertex interests/activities at ATMP cell and gene therapy Contract Manufacturing Organizations (CMOs)
* Provide operational oversight of, and troubleshooting support to, CMOs to ensure all deliverables meet or exceed Vertex and regulatory requirements (including but not limited to successful execution of manufacturing operations, on-time shipments, quality compliance and cost management); be Vertex's "eyes and ears" at the CMO for right-first-time execution of commercial operations.
* Proactively "connect the dots" on emerging trends and issues and lead/influence cross functional teams to drive resolutions and minimize impact to compliance and delivery of safe and reliable supply
* Maintain on-site presence at CMO facilities for extended periods (including off hours/weekends) to oversee (i) critical program activities, (ii) clinical and commercial batch manufacturing until the CMO is sustainably executing operations, and (iii) Health Authority inspections.
* Leverage Technical, Quality and Regulatory SMEs to provide guidance to CMOs and ensure cross-functional alignment on program priorities and deliverables from clinical through commercial manufacturing and supply.
* Liaise closely with internal and CMO stakeholders and leadership to drive Vertex business operations priorities including but not limited to (i) contract management (including tracking KPIs and metrics e.g. for batch release, inventory targets and schedule attainment), (ii) forecast communication and schedule alignment, (iii) supplier governance (including Vertex Quality/other audits) and (iii) finance (e.g. issuance of POs and reconciliation/validation of invoices; tracking of spend vs budget).
* Manage and track CMO performance prior to (preparation), during (direct oversight) and after (campaign summaries/reports) manufacturing.
* Manage and track batch data in appropriately compliant (data-integrity) systems to support filing submissions, patient planning and process optimization.
* Work closely with CMO and internal Quality and Technical teams to prioritize, monitor, track, review and deliver required compliance documentation (including but not limited to change controls, investigations and deviations, batch data, CAPA effectiveness, internal/external audit observation deadlines, regulatory commitments) to meet Vertex program requirements.
* Identify and escalate business-critical issues to Commercial Manufacturing and Supply Chain, CMC, and Quality leadership.
* Collaborate with CMO and internal stakeholders to understand planned changes and manage the end-to-end implementation of agreed changes including but not limited to change controls and impact assessments.
* Lead continuous improvement initiatives to affect timely resolution of supply issues.
* Build and maintain strategic relationships within the CMO organization as well as key internal stakeholders.
Minimum Requirements:
* Bachelor's degree required, ideally in cell biology, or closely related in Life Sciences disciplines (Immunology, Microbiology, Cell Biology, Engineering, etc.) with 10+ years of relevant experience in biotech or pharmaceutical industries, ideally in a senior manufacturing/operations leadership role working with or in cGMP facilities within the biotechnology industry.
* Strong quality and compliance background in a commercial GMP biopharmaceutical operations (manufacturing and quality) environment; sound working knowledge of health authority regulations.
* Strong technical background in aseptic manufacturing operations.
* Solid project management skills and experience managing complex projects.
* Strong verbal and written communication skills: ability to express oneself clearly and concisely, by adjusting style, language and/or terminology as appropriate for the audience.
* Strong leadership and an innate ability to collaborate and build relationships is critical.
* Ability to work calmly and make sound decisions in a fast-moving environment of uncertainty and change
* Flexibility to work shift hours required to cover critical process steps
* Ability to travel, national and international, up to 50%
* Excellent computer skills including Microsoft (Word, Excel, Project, Outlook, Teams), equipment interfaces and electronic quality systems
Desired Additional Skills:
* Strong technical background in cell and genetic therapy related manufacturing operations, ideally autologous cell therapy experience.
* Solid experience in equipment and facility qualification and validation for ATMP CMO's
* Cleanroom qualification (Grade A/B) history
Environment:
* Office and cleanroom - must be able to comply with cleanroom gowning requirements at CMO
* Must be able to remain in a stationary position 50% during cleanroom processing activities
* Must be comfortable moving about inside the cleanroom to oversee process tasks
* Compressed gasses and LN2 are commonly used in manufacturing operations
* Human tissue (e.g. apheresis) and cellular materials are commonly used
Pay Range:
$160,000 - $240,000
Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
Remote-Eligible
Flex Eligibility Status:
In this Remote-Eligible role, you can choose to be designated as:
1. Remote: work remotely five days per week and come into the office on occasion - you're always welcome on-site; or select
2. Hybrid: work remotely up to two days per week; or select
3. On-Site: work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.
#LI-Remote
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com
$35k-51k yearly est. Auto-Apply 4d ago
Global Development FP&A Director - Clinical Budget & Strategy
Vertex Pharmaceuticals 4.6
Boston, MA job
A leading biotechnology company in Boston seeks a Senior Director of Global Development FP&A to spearhead financial planning and analysis for clinical trials. The ideal candidate has deep expertise in clinical trial finance, project management, and cross-functional collaboration. Responsibilities include managing complex budgets and providing strategic insights to senior leadership. This hybrid-eligible role offers a competitive salary and benefits package.
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$173k-236k yearly est. 3d ago
Associate Scientist
Intellia 4.4
Intellia job in Cambridge, MA
Why Join Intellia?
Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.
Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to excel and succeed together. We believe in the power of curiosity and pushing boundaries. We welcome challenging thoughts and imagination to develop innovative solutions. And we know that patients are counting on us to make the promise a reality, so we must maintain high standards and get it done.
We want all of our people to go beyond what is possible. We aren't constrained by typical end rails, and we aren't out to just “treat” people. We're all in this for something more. We're driven to cure and motivated for change. Just imagine the possibilities of what we can do together.
How You Will Achieve More With Intellia:
Design, synthesis, purification, and characterization of lipids to be formulated into lipid nanoparticles. Propose novel lipids and structure-activity relationships (SAR) based on biological assay data. Use background knowledge in organic chemistry to troubleshoot experiments to achieve research goals. Use analytical tools such as column chromatography, LCMS, and NMR to determine compound structure and provide high quality lipids for formulation. Conduct experiments independently and in collaboration with colleagues in support of project goals. Register compounds in internal chemistry database and assist with maintenance/improvement of existing systems. Communicate research findings with internal stakeholders. Assist in the preparation of peer-reviewed publications, patents, and/or scientific presentations. Assist in chemistry lab operations, including the ordering of supplies and maintenance of equipment.
About You:
Requires a Master's degree (or foreign equivalent) in Chemistry or a directly related field plus two (2) years of experience as a Researcher, Scientist, or a related occupation in biotech or pharmaceuticals. Experience must include:
Must have two (2) years of experience with the following (experience may be gained concurrently):
Synthesis and purification of lipids for mRNA delivery.
Synthesis and purification of fluorophores and tool compounds.
Fluency in normal and reverse-phase chromatography and NMR structure elucidation.
Compound registration and maintenance/improvement of database systems.
Employer will accept a Bachelor's degree (or foreign equivalent) plus five (5) years of experience as a Researcher, Scientist, or a related occupation in biotech or pharmaceuticals in lieu of a Master's degree plus two (2) years of experience.
40 hours/week, 9:00am-5:00pm.
Cambridge, MA
#LI-DNI
Covid-19 Vaccination Policy:
All Intellia employees, regardless of work location, are expected to follow all applicable federal, state, and local public health regulations and guidelines, and are strongly encouraged to follow all public health recommendations, including being vaccinated for COVID-19.
EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
$68k-96k yearly est. Auto-Apply 60d+ ago
Vertex Summer 2026 Intern, Process Chemistry
Vertex Pharmaceuticals 4.6
Boston, MA job
Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you'll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We're passionate about innovation, inclusion, and supporting your growth-inside and outside the lab.
Why Vertex?
Real Projects: You'll work on assignments that make a real impact, not just busy work.
Mentorship & Networking: Connect with leaders and peers who want to see you succeed through professional networks, connections, and collaborations that will shape your longer-term career.
Flexible & Supportive: We offer flexible work options with Flex @ Vertex and prioritize your wellbeing.
Inclusive Culture: Collaboration and inclusion are embedded in everything we do.
Career Launchpad: Build skills, explore career paths, and get guidance for your future career.
Ready to apply? Submit your application and let's turn possibilities into reality!
Your Impact
The Vertex Research internship program is a multi-week experiential training program for students currently working towards an undergraduate degree in Chemistry, or a related field of study. If you are passionate, collaborative, and growth-minded, an internship at Vertex will help you gain meaningful experience in our Drug Substance Development functional areas and serve as a launchpad for your career.
Important Notice Regarding Internship and Co-op Inquiries
At Vertex Pharmaceuticals, we are committed to providing a fair and structured recruitment process for all students interested in internship and co-op opportunities. To ensure consistency and equity, all student applications must go through our Early Talent Acquisition Team.
Due to the high volume of interest, we are unable to respond to individual solicitation. Direct solicitation to Vertex employees- including senior leaders via email will result in removal from the recruiting process.
We appreciate your enthusiasm and interest in Vertex. To be considered for internship or co-op roles, please apply directly through our official application channels. (**************************************************************************
Thank you for respecting our process and helping us maintain a fair experience for all candidates.
What you will be doing:
As part of Drug Substance Development Team, we apply synthetic organic chemistry and process chemistry principles and techniques in the development of practical processes for Active Pharmaceutical Ingredients (APIs) amenable for mass production. The summer Intern will gain professional hands-on experience working in a pharmaceutical company. An understanding of synthetic organic chemistry with laboratory experience is expected.
As a Process Chemistry Intern, you will have the opportunity to
Work closely with an experienced process chemist to learn the fundamental knowledge and laboratory techniques on process development and optimization, synthesis and characterization of small molecule organic compounds, developing analytical thinking and problem-solving skills.
Maintains a well-written and organized notebook
Involves in group discussion, present work and communicate with other team members
What you will need to succeed:
This position is fully onsite at our Boston MA location
Must be pursuing a Bachelor's degree in chemistry
Undergraduate student with completion of a minimum of one year of university studies
Completed college coursework for General Chemistry and Organic Chemistry and associated laboratory work
Excellent communication, collaboration and interpersonal skills
Legal authorization to work in the United States, now and in the future. Please note that Vertex does not provide sponsorship for internships or entry level roles within this part of the organization.
You must be enrolled in an advanced degree program if graduating before August 2026
You must be available to work full-time, 40 hours per week from May - August 2026
Program Details:
Full-time, paid internship $20.00 - 27.00 USD/hour
Program Dates: May - August 2026
At Vertex, we believe that when you feel your best, you can perform at your best. That's why our US benefits and global well-being resources are designed to support you.
• Free 24/7 onsite gym access and free access to group exercise classes
• Subsidized commuter benefits- transit and parking
• Provided meals-free breakfast daily!
• Career development opportunities and events, including C Suite engagement
• Social events-both intern-only and company-wide
• Location-specific perks and extras!
• Recognition of National Intern Day
Equal Opportunities
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Vertex is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements.
Accessibility & Accommodations
We're focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best. Vertex is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com.
Export Control Notice
This position may involve access to technology or data that is subject to U.S. export control laws, including the Export Administration Regulations (EAR). As such, employment is contingent upon the applicant's ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements, only individuals who qualify as U.S. persons (citizens, permanent residents, asylees, or refugees) are eligible for this position. For this role, Vertex is unable to sponsor non-U.S. persons to apply for an export control license.
This job posting is for a temporary role with a third-party agency partner that provides services to Vertex. The individual selected for this role will be offered the role as an employee of that third-party agency; compensation, medical benefits, fringe benefits and other terms and conditions of employment shall be presented by the third-party agency upon offer.
For any questions or concerns, please contact early_***************.
Pay Range:
$0 - $0
Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
Hybrid-Eligible Or On-Site Eligible
Flex Eligibility Status:
In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.
#LI-Hybrid
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com