Ironwood Pharmaceuticals jobs - 255 jobs

A leading biopharmaceutical company is seeking a Global Commercial Director for Immunology Cell Therapy based in Boston. In this role, you will develop and implement commercial strategies and lead initiatives for launching new therapies in the market. Ideal candidates will have over 10 years of experience in pharmaceutical development and a strong understanding of commercial strategies. This position offers a salary range of $229,303 to $343,955 annually, along with various benefits, including health coverage and retirement plans. #J-18808-Ljbffr

A global biopharmaceutical company based in Boston seeks a Director, Safety Scientist to lead risk management and mentor junior scientists. Responsibilities include managing safety evaluations, preparing regulatory documents, and representing global safety at inspections. Ideal candidates have advanced degrees and over 7 years in drug safety, with experience in risk management regulations. Offering competitive salary, incentives, and diverse benefits. #J-18808-Ljbffr

A leading pharmaceutical company is seeking a Senior Principal Analyst to act as a strategic liaison between Marketing stakeholders and technical teams. This role focuses on optimizing the Marketing Technology ecosystem while ensuring compliance with industry regulations. The ideal candidate will have 8+ years in Marketing Technology, with deep expertise in tools like Salesforce Marketing Cloud and Tealium. Strong project management and communication skills are essential, along with the ability to translate requirements into clear deliverables. This role offers a hybrid work environment with competitive benefits. #J-18808-Ljbffr

Senior Medical Science Liaison - Nephrology (Michigan: East) page is loaded## Senior Medical Science Liaison - Nephrology (Michigan: East)locations: Boston, MAtime type: Full timeposted on: Posted Todayjob requisition id: REQ-26679**Job Description****General Summary:**The Senior Medical Science Liaison (Sr MSL) (Nephrology) for Povetacicept programs. Povetacicept (pove) is an enhanced, dual BAFF/APRIL inhibitor in pivotal development for the treatment of IgA Nephropathy (IgAN).The Sr MSL will serve as a scientific liaison to the medical/academic community and is responsible for establishing and maintaining relationships with Health Care Providers/Professionals (HCPs) to ensure the appropriate dissemination of clinical and scientific information regarding Vertex' compounds in a timely, ethical and stakeholder-focused manner. The Sr MSL will contribute to shaping the medical plan by providing external stakeholders' insights and contribute to the designing and execution of the Medical Affairs strategy and plan. The Sr MSL will engage HCPs in response to scientific educational and research needs with available Vertex resources and provide the latest emerging data in response to specific inquiries, as appropriate.**Key Duties and Responsibilities:*** Develops and fosters effective and trusting relationships with Thought Leaders (TL) and identifies and engages other appropriate HCPs resulting in scientific engagement with a large network of T1D and transplant-team care providers and opinion leaders. Additionally, understands the inter-relationships both within and between academic centers and utilizes this expertise to enhance Thought Leader and HCP engagements* Consistently incorporates all aspects of the SEM (Scientific Engagement Model) into all interactions, enhancing the quality of interactions and overall relationships as assessed by field coaching observations* Independently incorporates the medical plan into interactions and territory planning (i.e. listening priorities) and captures valuable feedback in the CRM system to inform internal stakeholders and assist in shaping the medical strategy* Possesses an in-depth understanding of the utility and functionality of the CRM system/data analytics tools, allowing for the time sensitive capture of interaction details. Uses CRM/Analytics to enhance future TL engagements and manage workload* Discusses scientific information effectively and compliantly with external stakeholders at an advanced level of communication for both disease state and product to external stakeholders as assessed by management coaching and field observations* In-depth conceptual and practical knowledge of payers in the region and possesses an in-depth understanding of the impact of payers on patient care delivery* Assists clinical development/clinical operations by fully understanding IB content and presenting IB material, providing nominations for trial sites as requested, providing end of study data reviews with investigators (as needed)* Represents Vertex at medical congresses by providing scientific session/abstract coverage, booth staffing coverage, routine TL interactions, contributing to the daily and end of congress summaries and may provide logistical guidance through organizing and scheduling abstract/session coverage and preparing and delivering the conference debrief (as needed)* May serve as a mentor or trainer for colleagues with less experience; for example, assisting with new hire MSL onboarding* Conducts all activities in compliance with Vertex policy and procedures and performs all administrative tasks in a timely manner such as CRM entry, vehicle mileage reporting, expense reporting, calendar entries, training assignments, etc.**Knowledge and Skills:*** Ability to complete goals within allotted timeframes, and deliver high quality results* Ability to help plan and complete projects in a constantly changing field-based environment* Ability to appraise and comprehend medical and scientific literature* Ability to effectively present clinical/scientific information in a credible manner in varied settings* Good knowledge of assigned geographic territory* In-depth understanding of healthcare regulatory environment* Apply proficient knowledge of relevant T1D and T1D management protocols, healthcare environment and landscape to articulate the medical and scientific value of our products* Demonstrated working understanding around the compliance and regulatory frameworks that govern the pharmaceutical industry and conducts compliant interactions with internal and external stakeholders.* In-depth knowledge of payers and unique medical information needs to support access and appropriate use of Vertex medicines* Good knowledge of Health Economics and Outcomes Research* Fluent in English (oral and written)**Education and Experience:*** Minimum requirement for advanced biomedical or life sciences degree (ex. Masters, NP, PA)* Requires minimum of 3-4 years of experience as an MSL supporting Nephrology programs or in other medical affairs roles in the pharma/biotech industry or the equivalent combination of education and experience.* Previous training or experience in designated therapeutic area is helpful Pay Range:$171,300 - $245,000Disclosure Statement:The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.**Company Information**Vertex is a global biotechnology company that invests in scientific innovation.Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com. #J-18808-Ljbffr

A leading biotechnology company in Boston is seeking an experienced Senior Director, Finance Technology to drive innovation across Financial Systems, focusing on Tax, Treasury, and Accounting. The ideal candidate will have over 12 years of experience in financial systems leadership, strong stakeholder engagement skills, and a passion for technology. This role offers competitive compensation and hybrid work options. #J-18808-Ljbffr

A global biotechnology company is seeking a Director of R&D Quality Governance & Risk Management to lead and enhance the governance framework supporting risk-based decisions. This strategic role requires 10+ years of R&D QA experience, strong leadership presence, and operational agility. Candidates should possess exceptional collaboration skills and mentorship capabilities. The role offers flexibility in a hybrid work environment with competitive compensation and comprehensive benefits. #J-18808-Ljbffr

A global biotechnology company is seeking a Senior Manager for their Order to Cash function to drive cash flow optimization and manage credit control. This role requires excellent stakeholder management and financial analysis skills. The successful candidate will work closely with various teams, present updates to senior leadership, and have opportunities for personal development in a hybrid-eligible environment. Experience in pharmaceutical or large organizations is preferred. #J-18808-Ljbffr

Are you ready to revolutionize Cell & Gene Therapy? Join us in shaping the future of therapeutics! We are seeking a Senior Mechanical & Automation Engineer in our journey of developing cutting‑edge manufacturing solutions for Casgevy-a first‑of‑its‑kind therapy transforming the treatment of Sick Cell Disease and Beta Thalassemia. In this role, you will be at the forefront of automating complex processes in one of the most dynamic and rapidly evolving fields in biotechnology. By leveraging your expertise in mechanical engineering and automation, you will play a pivotal role in streamlining manufacturing, enhancing manufacturing reliability, and scaling life‑saving therapies to reach patients faster. You will work with a passionate team of scientists, engineers, and innovators, all united by a shared mission: to push the boundaries of what's possible in Cell & Gene Therapy. This role reports to the Associate Director of Automation, Equipment, and Processes. Key Responsibilities Development of industrial machinery and automation from concept through commercial deployment. Manage the evaluation and selection of new equipment/technologies or modifications to existing systems required for scale up. Mechanical Design and integration, including, but not limited to robotics, single‑use sets, single‑use set cartridges, conveyors, AGV/AMRs, cam‑followers, peristaltic pumps, pinch valves, MFCs, solenoid valves, and process analytical technologies, and more. Mechanical Design Analysis, including, but not limited to kinematic design & analysis, dynamic analysis, stress analysis, tolerance stack analysis, mechanism design, cycle time calculation, utilization calculations, and cam‑follower design. Aseptic and GMP design. Design for compatibility with cleaning and sterilization. Single Use Set Design experience. Interface and collaborate with controls resources for joint electro‑mechanical designs. Manage vendors and perform design reviews, FATs, and SATs. Support validation activities. Create a scale up plan from concept through commercial equipment deployment. Provide support to non‑engineering Staff, including those from R&D and Manufacturing, to ensure successful technology transfer and continuous improvement. Support optimization and improvement in equipment/systems/processes. Establish equipment documentation, including parts lists, mechanical drawings, and assembly drawings. Provide engineering change documentation as appropriate. Statistically characterize equipment performance and implement designs to ensure repeatability and consistency. Design and manage vendor design of 3D CAD models. Collaborate with vendors to produce prototype and production parts. Create Equipment layouts in AutoCAD and/or Revit. Create drawings to ASME Y14.5M-200977. Understand and apply other respective standards within machine design, including ANSI and ISO standards. Provide hands‑on troubleshooting, equipment, and manufacturing assistance in support of a rapid development cycle and manufacturing sustainability. Execute assigned duties on time and within budget; proactively communicate delays and other issues to relevant stakeholders. Comply with all regulatory, corporate, and Quality System policies. Support Deviation Management, CAPA, and Change Control activities, as required. Perform other duties as assigned. Required Qualifications BS or MS in engineering or another relevant discipline. 5+ years of experience working within an automation development environment (pharmaceutical, cGxP preferred). Experience with cell & gene therapy is highly desirable. Experience working with a variety of automation hardware, including but not limited to custom‑fabricated mechanical components, cam systems, linkages, index and dwell machines, cartesian robots, SCARA robots, end‑of‑arm tooling, and dip coating. Experience developing single‑use sets. Understanding of cGxP principles and practices and familiarization with ISO 13485, ISO 14971, and 21CFR820 is a plus. Knowledge of global cGMP requirements governing device or combination products. Experience with 3D CAD software, preferably with SolidWorks. Experience troubleshooting industrial automation. A strong understanding of statistical principles is required, as are strong technical writing and presentation skills. Must be able to work independently with adequate supervision, multi‑task, and support several projects simultaneously. Sense of urgency, ability to act/escalate promptly, and transparently communicate issues to involved stakeholders and management. Must demonstrate strong interpersonal, presentation, and teamwork skills. This is a 5 days a week role, requiring 3 days onsite per week at our Boston and Rhode Island offices. Pay Range $75/hr - $90/hr. Shift/Hours Monday-Friday Requisition Disclaimer This job posting is for a temporary role with a third‑party agency partner on assignment at Vertex Pharmaceuticals (“Vertex”). The individual selected for this role will be offered the role as an employee of a third‑party agency partner; compensation, medical benefits, fringe benefits and other terms and conditions of employment shall be presented by the third‑party agency partner upon offer. The pay rate range provided is a reasonable estimate of the anticipated compensation range for this job at the time of posting. The actual pay rate will be based on a number of factors, including skills, competencies, experience, location and other job‑related factors permitted by law. In addition, this role will be eligible for overtime pay, in accordance with federal and state requirements. No C2C or Third‑Party Vendors. #J-18808-Ljbffr

**Job Description**Vertex is growing at a rapid pace with challenging and exciting opportunities for motivated professionals who are keen to contribute to the Vertex mission to invest in scientific innovation to create transformative medicines for people with serious diseases. Our robust and complex R&D pipeline requires a focus on efficiency and prioritization as we scale. The Vertex finance function is integral to achieving our company's strategic goals, providing critical insights and analysis in support of decision-making across the organization. We are investing in our ability to provide data-driven insights by organizing and automating financial data and processes to enable our growing global scale. We are also leveraging best practices to strengthen our business partnering and decision support capabilities. By joining our function, you will become part of a fast-moving, forward-thinking team to support the ongoing growth of a leader in the biotechnology industry.**General Summary:**The Senior Director, Global Development FP&A is a seasoned finance leader who partners directly with our Global Clinical Development (early- and late-stage programs) organizations and cross-functional program teams to run global financial planning, forecasting, and strategic analysis. Reporting to the VP of R&D Finance, this highly visible role serves as a strategic advisor to the Chief Medical Officer's organization and senior leadership, influencing portfolio prioritization and investment decisions through financial insights. The ideal candidate brings deep expertise in clinical trial finance, executive presence, and a proven ability to drive business outcomes in a dynamic, science-driven environment.This role is for you if you possess strong decision support analytical skills, project management expertise, team management skills, and demonstrated ability to collaborate with cross-functional teams to drive innovation and deliver successful product development outcomes.**Key Duties and Responsibilities:**A key leader in financial planning and analysis within our function, your responsibilities entail:Advanced Scenario Planning and Risk Analysis:* Build, maintain, and own clinical program-level budgets (Phase 1 to Phase 3), clinical trial cost models, and forecasts; produce cost-to-complete and cost per patient analysis used in strategic decisions.* Lead advanced scenario modeling for clinical programs, including sensitivity analyses on timelines, enrollment rates, and regulatory milestones to inform go/no-go decisions.* Translate clinical development plans into financial implications and ROI-based recommendations.Strategic Influence and Business Partnership:* Participate in cross-functional program teams and governance committees, providing real-time financial guidance.* Deliver program dashboards, KPIs and trend analyses for executive and portfolio reviews.* Prepare and present executive-level updates.Team Leadership:* Lead and develop a team of 6-8 clinical finance professionals: set team priorities, establish processes, and build scalable operating mechanisms for financial support* Drive automation and digital transformation of clinical finance processes, leveraging tools like Hyperion, Oracle, and emerging analytics platforms to improve accuracy and scalability* Mentor staff on forecast accuracy, stakeholder management and financial modeling best practices* Drive a collaborative, service-oriented culture between finance and Global Clinical Development organizations Governance and Compliance Leadership:* Oversee month-end and quarter-end close activities related to clinical expense (accruals, reconciliations, GL review).* Ensure accurate, timely accruals for CROs, FSPs, sites, labs and other clinical vendors. Maintain audit-ready documentation for clinical program spend* Improve transparency and accountability around clinical opex and resource allocation through clear processes, benchmarks and metrics**Basic Requirements:*** Bachelor's degree in finance, Accounting, or related field; MBA or CPA/CFA strongly preferred.* 12+ years of progressive FP&A experience, with at least 5 years in the pharmaceutical or biotech industry.* Experience supporting R&D or Clinical Development functions at a global scale.* Strong understanding of R&D processes, portfolio management, and project evaluation methodologies.* Proven ability to manage complex budgets, forecasts, and analyses in a dynamic, fast-paced environment.* Excellent communication and presentation skills, with the ability to influence stakeholders at all levels and a proven ability to present complex financial insights to senior stakeholders.**Important Knowledge and Skills:*** Deep understanding of pharmaceutical industry dynamics and executive-level business partnering.* Hands-on exposure to clinical operations and/or CRO/FSP budgeting.* Strong analytical capabilities in portfolio analysis.* Proficiency in Microsoft Office and financial systems, including Hyperion and Oracle.* Proven ability to lead change in complex, cross-cultural matrix environments.* Exceptional communication and influencing skills across senior leadership and cross-functional teams.* Ability to apply broad market knowledge to drive financial performance and strategic outcomes.* Strategic thinker with attention to detail.#LI-DB1#HYBRID**Pay Range:**$212,000 - $318,000**Disclosure Statement:**The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.**Flex Designation:**Hybrid-Eligible Or On-Site Eligible**Flex Eligibility Status:**In this Hybrid-Eligible role, you can choose to be designated as: 1. **Hybrid**: work remotely up to two days per week; **or select** 2. **On-Site**: work five days per week on-site with ad hoc flexibility.Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.#LI-Hybrid**Company Information**Vertex is a global biotechnology company that invests in scientific innovation.Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com #J-18808-Ljbffr

A leading biotechnology company is seeking an Associate Director, Global Pain Market Research to join its Boston team. In this role, you will oversee commercial insights supporting the Global Commercial Strategy for pain management. Key responsibilities include designing primary market research and developing the annual situation analysis. Candidates should have a Bachelor's degree and 8+ years of relevant experience in market research and bio-pharma marketing. Flexible work options are available. #J-18808-Ljbffr

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you'll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We're passionate about innovation, inclusion, and supporting your growth-inside and outside the lab. Why Vertex? Real Projects: You'll work on assignments that make a real impact, not just busy work. Mentorship & Networking: Connect with leaders and peers who want to see you succeed through professional networks, connections, and collaborations that will shape your longer-term career. Flexible & Supportive: We offer flexible work options with Flex @ Vertex and prioritize your wellbeing. Inclusive Culture: Collaboration and inclusion are embedded in everything we do. Career Launchpad: Build skills, explore career paths, and get guidance for your future career. Ready to apply? Submit your application and let's turn possibilities into reality! Your Impact The Vertex Clinical and Quantitative Pharmacology internship program is a multi-week experiential training program for students currently working towards a Doctoral degree in pharmacology or PharmD, or a related field of study. If you are passionate, collaborative, and growth-minded, an internship at Vertex will help you gain meaningful experience in our research functional areas and serve as a launchpad for your career. Important Notice Regarding Internship and Co-op Inquiries At Vertex Pharmaceuticals, we are committed to providing a fair and structured recruitment process for all students interested in internship and co-op opportunities. To ensure consistency and equity, all student applications must go through our Early Talent Acquisition Team. Due to the high volume of interest, we are unable to respond to individual solicitation. Direct solicitation to Vertex employees- including senior leaders via email will result in removal from the recruiting process. We appreciate your enthusiasm and interest in Vertex. To be considered for internship or co-op roles, please apply directly through our official application channels. (************************************************************************** Thank you for respecting our process and helping us maintain a fair experience for all candidates. What you will be doing: The Clinical and Quantitative Pharmacology (CQP) department at Vertex leads clinical pharmacology and clinical modeling & simulation efforts across all disease areas and clinical phases of drug development. There will be two CQP summer internship positions available with the opportunity to work with experienced mentors within CQP. A Vertex CQP summer internship will provide a 12-week hands-on opportunity to experience some of the elements of CQP within drug development. Based on the project, an intern may participate in numerous activities, such as design and conduct of clinical pharmacology studies (e.g., first-in-human, drug interaction, food effect, special populations, ADME), or exploration of drug pharmacokinetic (PK) and pharmacokinetic/pharmacodynamic (PK/PD) relationships and related analyses (e.g. population PK or other advanced modeling). Activities the successful candidate may be involved in include literature research, drafting and reviewing clinical study protocols, reviewing clinical study report sections, creating analysis plans, learning to manipulate and create clinical analysis-ready datasets, build and evaluate models, execute analyses, and prepare informative outputs, graphics, and results representations. During the 12-week appointment, the summer intern will also be exposed to various aspects of the drug development process and thereby gain a view into how the CQP functions fit within broader cross-functional drug development teams that often include preclinical disciplines, clinical development, clinical operations, bioanalysis, biostatistics, and more. Not only will interns learn about their day-to-day responsibilities, but they will interact with scientists from various levels, and with organizational leaders and their teams through a series of Professional Development Workshops that are provided during the summer. Clinical and Quantitative pharmacology activities may include the following (project dependent): Research literature, published studies, and regulatory guidance Learn to work with and manipulate clinical data and data constructs Analyses of data collected from literature or clinical trial PK and/or PK/PD data in NONMEM, R and/or related software Summarize the main findings Prepare presentation(s) for various internal forums What you will need to succeed: Enrolled in a PhD or PharmD program in pharmacology, or a related field of study by Fall 2025. Communicate clearly through verbal and written communication Understanding of drug metabolism, PK, and PK/PD principles Knowledge of protein therapeutics preferred Quantitative and hands-on skills preferred: PK and/or PK/PD analyses Experience with data analysis tools such as R, Phoenix WinNonlin, NONMEM or other programming/software applications Prior industry experience preferred but not required Legal authorization to work in the United States, now and in the future. Please note that Vertex does not provide sponsorship for internships or entry level roles within this part of the organization. You must be available to work full-time, 40 hours per week from May - August 2026 Program Details: Full-time, paid internship $33.00 - 50.00 USD/hour Program Dates: May - August 2026 At Vertex, we believe that when you feel your best, you can perform at your best. That's why our US benefits and global well-being resources are designed to support you. • Free 24/7 onsite gym access and free access to group exercise classes • Subsidized commuter benefits- transit and parking • Provided meals-free breakfast daily! • Career development opportunities and events, including C Suite engagement • Social events-both intern-only and company-wide • Location-specific perks and extras! • Recognition of National Intern Day Equal Opportunities Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Vertex is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements. Accessibility & Accommodations We're focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best. Vertex is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com. Export Control Notice This position may involve access to technology or data that is subject to U.S. export control laws, including the Export Administration Regulations (EAR). As such, employment is contingent upon the applicant's ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements, only individuals who qualify as U.S. persons (citizens, permanent residents, asylees, or refugees) are eligible for this position. For this role, Vertex is unable to sponsor non-U.S. persons to apply for an export control license. This job posting is for a temporary role with a third-party agency partner that provides services to Vertex. The individual selected for this role will be offered the role as an employee of that third-party agency; compensation, medical benefits, fringe benefits and other terms and conditions of employment shall be presented by the third-party agency upon offer. For any questions or concerns, please contact early_***************. Pay Range: $0 - $0 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

A leading biotechnology company is looking for an HCP Marketing Associate Director to lead innovative marketing strategies for a new kidney therapy. The ideal candidate will have experience in specialty product launches and a proven track record in healthcare marketing. This role offers a hybrid work schedule, with options for remote work and extensive benefits including generous paid time off and educational assistance programs. Join a team dedicated to transforming patient lives through strategic marketing initiatives. #J-18808-Ljbffr

A leading global biotechnology firm in Boston seeks a Principal Engineer to lead the automation of pre-clinical data pipelines and regulatory reporting solutions. This role focuses on driving modernization and standardization initiatives, leveraging AI technologies, and enhancing data consumption practices. Candidates should possess strong programming skills and a degree in a relevant field, with a minimum of five years in technical leadership within the biotechnology industry. The position offers a hybrid work model and a comprehensive benefits package. #J-18808-Ljbffr

The Senior Meetings & Events Planner will be responsible for delivering strategic meeting planning for a variety of meetings independently and with the support of preferred logistics vendors. This role will be skilled in ensuring seamless execution of highly complex events while fostering strong relationships with global teams and suppliers. The ideal candidate will demonstrate problem-solving and interpersonal skills with a global point of view, and partner with cross-functional planning teams to ensure meeting logistics and planned activities are aligned and support the overall meeting goals and objectives. The ideal candidate must possess strong HCP/Compliance knowledge and experience and the ability to act as a solid meetings management resource both internally and externally. Key Duties & Responsibilities Provides strategic guidance support and management to preferred logistics agencies on an event-by-event basis. Strong project management skills managing multiple projects, vendors, and processes. Consult and navigate cross-functional planning teams, vendors, and Business Owners through complex logistical planning by setting roles & responsibilities, adherence to HCP compliance and transfer of value, meeting best practices and strategy, and expectation of deliverables. Demonstrated ability to build and manage complex budgets and guide vendors to manage multiple budgets with different timelines and deliverables. Identify and resolve day-to-day matters related to project requirements, cross-functional processes, and vendor management operations. Build and maintain strong partnerships with Business Owners and consult on meeting goals & objectives to provide strategic support solutions. Ability to strategically engage and advise Business Owners across diverse meeting formats and therapeutic areas Must possess ability to manage, communicate and interact with various of levels of internal business owners in professional and knowledgeable manner at all times Strong adherence to internal & HCP compliance, transparency rules and reporting, knowledge and understanding of GDPR requirements. Ability to travel domestically and globally at least 30% of the time. Required Education Level • Bachelor's Degree Required Experience 5+ years of global meeting & event planning experience Previous Pharmaceutical Experience a plus Supplier/Vendor management experience a plus Required Knowledge/Skills Proficient and professional meeting planning experience in a corporate setting. Strong organization and time management skills, ability to simultaneously keep multiple projects prioritized and moving with multiple stakeholders. Experienced contract negotiations skills with in-depth understanding of hotel and venue legal and business terms. Ability to guide negotiations of venue and vendors contracts, securing the best possible terms to provide Vertex with the most flexibility, financial security and cost saving opportunities. Strong verbal and written communication skills, comfortable in group and individual presentations across all levels of the organization. Strong knowledge of HCP Compliance regulations and ability to apply critical thinking to identify and escalate compliance risks to the Office of Business Integrity & Ethics while adhering to and implementing guidelines and monitoring team adherence. Committed to delivering the highest level of customer service. Flexibility and ability to successfully navigate ambiguity and succeed in a rapidly changing, fast-paced, deadline-driven environment with multiple priorities. A desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families and society. Other Requirements Proficient in Microsoft Office suite. Prior working knowledge of Cvent Event Management software program preferred. CMP and or CMM Certification (a plus but not required) #LI-hybrid #LI-TC1 Pay Range: $91,200 - $136,800 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

**Job Description****General Summary:**Vertex is seeking an experienced Order to Cash professional to join our Controllership organization as a senior manager within the Global Revenue Accounting team. The Controllership organization is integral in delivering Vertex's mission of creating transformative medicines for people with serious and life-threatening diseases. You will be working as part of a dynamic and diverse organization alongside outstanding people who are forward-thinking, collaborative and recognized leaders in their areas.The position is a key role within Global Revenue Accounting, and we are seeking an experienced and strategic Senior Manager within Order to Cash “O2C” to manage our credit control function, drive cash flow optimization, manage internal controls and implement solutions that strengthen financial performance. The successful candidate will combine hands-on credit control expertise with strategic insight, leading a team of two to maximize collections, minimize risk, and support business growth.Central to this role is fostering exceptional working relationships across the Controllership function, Global Supply Chain, our third-party logistics providers, and regional finance teams. The individual will also be well organised, comfortable presenting and influencing senior stakeholders and able to manage competing deadlines.This role is highly visible across the international organisation and with our global head office in Boston and offers excellent opportunities for personal development and continuous improvement. As Vertex continues to grow, and expand geographically, the successful candidate will have many opportunities to shape processes and drive lasting change.**Key Duties and Responsibilities:*** Work with global finance, revenue accounting, trade ops, supply chain and market access teams to ensure we remain at the forefront of any changes to our ways of working* Implement and enforce credit policies and procedures that mitigate risk while supporting customer relationships* Present credit & collections updates to Senior Directors and Departmental Heads* Build strong relationships with our external service providers, internal stakeholders and business partners* Represent the team at Global Credit Committee meetings, interacting with the Global Finance and Chief Accounting Officer's leadership team* Develop and execute credit strategies that optimize cash flow, reduce Days Sales Outstanding (DSO), and minimize bad debt* Protect Vertex's credit risk with consideration for securitisation initiatives.* Design process solutions in support of key business decisions and new product/country launches* Drive improvements in our monthly Dashboard reporting* Drive transformation initiatives (system/process/policy)* Participate in global projects representing the needs and interests of the O2C and wider Revenue Accounting team* Analyse the performance of external service providers against KPIs* Ensure our ongoing compliance to all O2C related SOX controls**Knowledge and Skills:*** Ability to work collaboratively with external service providers, to ensure the highest standards of execution are maintained and the interests of Vertex and its patient remain forefront* Strong stakeholder management skills, able to quickly establish credibility and build effective, collaborative, working relationships at all levels* Excellent communication and interpersonal skills necessary for leading cross functional projects and presenting to senior management (including accounting, finance and commercial management)* Ability to partner with other functional areas to develop, improve and monitor compliance with policies and procedures including taking a leadership role on certain initiatives* Strong financial analysis and reporting skills* Strong knowledge of credit control, risk management, and regulatory compliance* Strategic thinker with ability to provide solutions to cash flow and credit challenges* People management skills, with experience motivating and developing teams* Solution-focused with experience in improving processes and systems* Ability to pivot based on demand and prioritization**Education and Experience:*** Bachelor's Degree in Accounting or Business administration, or equivalent business experience* Strong credit control/accounts receivable experience, in a managerial or leadership role* Experience in large, complex, or multinational organizations preferred* Experience in pharmaceutical industry preferred#LI-SG1#LI-Hybrid**Flex Designation:**Hybrid-Eligible Or On-Site Eligible**Flex Eligibility Status:**In this Hybrid-Eligible role, you can choose to be designated as: 1. **Hybrid**: work remotely up to two days per week; **or select** 2. **On-Site**: work five days per week on-site with ad hoc flexibility.Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.#LI-Hybrid**Company Information**Vertex is a global biotechnology company that invests in scientific innovation.Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com #J-18808-Ljbffr

A leading biotechnology company is seeking a Director, Global Process Excellence to enhance finance systems and processes integral to scaling operations. This role requires extensive finance experience, capability in project management, and leading cross-functional improvements. The position offers a hybrid work model and competitive salary range of $180,800 - $271,100, along with generous benefits and annual bonus eligibility. #J-18808-Ljbffr

A leading biotechnology firm in Boston seeks a Senior Mechanical & Automation Engineer. This role involves developing and automating manufacturing solutions for innovative therapies. Candidates should have extensive experience in automation development, mechanical design, and a strong understanding of cGxP principles. This is a five-day-a-week role requiring onsite presence for three days weekly. Compensation ranges from $75 to $90 per hour, with eligibility for overtime pay. #J-18808-Ljbffr

A leading biotechnology company in Boston seeks a Senior Director of Global Development FP&A to spearhead financial planning and analysis for clinical trials. The ideal candidate has deep expertise in clinical trial finance, project management, and cross-functional collaboration. Responsibilities include managing complex budgets and providing strategic insights to senior leadership. This hybrid-eligible role offers a competitive salary and benefits package. #J-18808-Ljbffr

could also be based in Basel, Switzerland. Ironwood Pharmaceuticals is a leading global gastrointestinal (GI) healthcare company on a mission to advance the treatment of GI diseases and redefine the standard of care for GI patients. We are pioneers in the development of LINZESS (linaclotide), the U.S. branded prescription market leader for adults with irritable bowel syndrome with constipation or chronic idiopathic constipation. Ironwood is also advancing apraglutide, a next-generation, long-acting synthetic GLP-2 analog being developed for rare gastrointestinal diseases, including short bowel syndrome with intestinal failure, as well as several earlier stage assets. Building upon our history of GI innovation, we keep patients at the heart of our R&D and commercialization efforts to reduce the burden of GI diseases and address significant unmet needs. As a Senior Medical Director, Clinical Development, you will be a critical leader within Ironwood's R&D organization. Reporting directly to the SVP of Research & Development, you will shape clinical strategy, design and execute clinical trials, and drive development of innovative therapies. This role requires outstanding interpersonal skills, strong learning agility, creativity, and the ability to analyze precedents - even from other therapeutic areas - to generate innovative, patient‑centric solutions. Essential Functions Clinical Leadership & Strategic Planning - Lead clinical development activities as both an individual contributor and cross‑functional leader. - Develop and refine the Clinical Development Plan (CDP). - Integrate regulatory, safety, and operational considerations. - Apply creative, cross‑therapeutic analytical thinking. Study Design, Execution & Oversight - Lead preparation of clinical documents (protocols, SAPs, CSRs, etc.). - Provide medical oversight ensuring safety and data quality. - Analyze and interpret clinical data and present strategic implications. - Train internal and external teams. Scientific Leadership & External Engagement - Support scientific publications and external collaborations. - Participate in regulatory interactions. - Represent Ironwood at scientific and strategic external meetings. Cross‑Functional Partnership - Build strong relationships across R&D. - Use interpersonal influence to align complex stakeholder groups. - Promote creativity and cross‑functional learning. Key Qualifications Education & Clinical Experience - MD or MD‑PhD required. - 8+ years of clinical drug development experience. - Rare disease experience preferred. - Gastroenterology experience preferred but not required. - Academic PI experience may be considered. Scientific & Technical Expertise - Strong knowledge of clinical research methodology. - Ability to analyze complex clinical data. - Knowledge of regulatory requirements and competitive landscape. Leadership & Interpersonal Skills - Exceptional communication and influence skills. - Proven leadership guiding cross‑functional teams. - Ability to build trust, navigate ambiguity, and drive alignment. Learning Agility & Creativity - Ability to learn new therapeutic areas quickly. - Creative problem‑solver. - Able to apply cross‑therapeutic insights. Operational Excellence - Experience overseeing CROs and vendors. - Strong project management and execution discipline. - Excellent written and oral scientific communication. Ironwood is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or protected veteran status. Ironwood currently anticipates that the initial base salary for this position could range from between $264,000 to $277,200. The actual base salary will depend, in part, on the successful candidate's qualifications for the role, including education and experience. Ironwood offers a comprehensive compensation and benefits program to eligible employees, including Restricted Stock Unit awards; eligibility to participate in either a bonus or sales incentive program; company-sponsored 401(k) with matching contributions; eligibility for medical, dental, vision and prescription drug benefits; wellness stipends; and a generous vacation/holiday schedule. #LI-Hybrid