PK/PD Modeling / Pharmacometrics Lead
Leader job in Detroit, MI
This person complements the client's “Translational / Clinical Pharmacology Decision-Maker” team by grounding dose selection and exposure-response analysis in **quantitative structure and parameter plausibility**.
### **Who we're looking for** - Deep hands-on experience in **PK, PD, exposure-response modeling**, and ideally **population PK or QSP**. - Expert at model fitting, sensitivity analysis, and identifying non-plausible parameter spaces. - Can evaluate the validity of dose-exposure predictions and detect high-risk extrapolations. - Comfortable designing **model evaluation rubrics** that distinguish between acceptable vs. non-credible outputs. - Able to articulate how quantitative checks should complement narrative decision logic. **Nice-to-have:** - Experience supporting translational or clinical pharmacology leads in dose justification. - Familiarity with integrating nonclinical PK/PD data (2-species GLP → human FIH extrapolation). ### **Experience level** - ~8-12 years of quantitative pharmacology experience in **pharma, CROs, or modeling consultancies**. - Strong portfolio in **population PK/PD**, **exposure-response**, and **parameter estimation** using NONMEM, Monolix, or equivalent tools. - Demonstrated ability to interpret model results for decision-making, not just fit data. - Can create **fit-for-purpose models** and critique model structures or assumptions under uncertainty. ### **Expectations** - Design and refine **micro-evaluations** for PK/PD performance (curve fits, parameter checks, error taxonomies). - Encode **quantitative sanity checks** into model rubrics for automated evaluation. - Define **failure conditions** (e.g., unsafe extrapolation, poor coverage curves, invalid assumptions). **Inputs we give:** - PK/PD datasets, tox summaries, and performance prompts (e.g., “fit exposure-response curves, interpret safety margins”). - Example model outputs from automated systems. **Expected outputs:** - **Quantitative Rubrics:** clear thresholds for acceptable parameter fits, coverage curve quality, and model integrity checks. - **Golden Fit Examples:** representative “ideal” PK/PD model outputs and visualizations for calibration. - **Error Taxonomy:** structured list of typical modeling or fitting errors, with root-cause annotations. - **Meta-Layer Commentary:** short note per rubric capturing how expert modelers recognize implausible or unsafe fits beyond numeric error values. ### **Engagement Model & Compensation** - **Contract / part-time**, remote, outcome-based deliverables.
Project Lead - Architecture | Interiors
Leader job in Detroit, MI
We are seeking a dynamic and experienced Project Lead specializing in Architecture and Interiors to oversee and manage our diverse range of projects. The ideal candidate will play a key role in leading design initiatives and collaborating with teams to deliver innovative and functional architectural solutions in various sectors, including hospitality, commercial spaces, and sports complexes.
Key Responsibilities
Lead and manage architectural projects from conception through to completion, ensuring quality and adherence to project timelines.
Collaborate with cross-functional teams including designers, engineers, and construction managers to develop design concepts and construction documentation.
Review and approve design drawings and documents to ensure compliance with regulations and standards.
Communicate effectively with clients, stakeholders, and team members to ensure alignment and satisfaction throughout the project lifecycle.
Mentor and guide junior architects and interns to foster professional growth and skill development within the team.
Stay updated on industry trends, regulations, and best practices to contribute to innovative design solutions.
Qualifications
Bachelor's or Master's degree in Architecture or a related field.
Minimum of 5 years of experience in architectural design and project management, with a strong portfolio of completed projects.
Proficiency in Revit and AutoCAD for architectural design and construction documentation.
Experience with hospitality, commercial, and sports architecture, particularly in the design of sports complexes.
Strong knowledge of AIA and NCARB regulations and standards in architecture.
Excellent communication, leadership, and interpersonal skills.
Benefits
Competitive salary
Bonuses
401k
Medical, Dental, Vision
Flexible Hybrid Schedule
PTO
Vacation
Sick Time
Email Your Resume In Word To
Looking forward to receiving your resume through our website and going over the position with you. Clicking apply is the best way to apply, but you may also:
levi.munn@cybercoders.com
Please do NOT change the email subject line in any way. You must keep the JobID: linkedin : LM5-1857759 -- in the email subject line for your application to be considered.***
Levi Munn - Sr. Executive Recruiter
For this position, you must be currently authorized to work in the United States without the need for sponsorship for a non-immigrant visa.
This job was first posted by CyberCoders on 06/25/2025 and applications will be accepted on an ongoing basis until the position is filled or closed.
CyberCoders is proud to be an Equal Opportunity Employer
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, sexual orientation, gender identity or expression, national origin, ancestry, citizenship, genetic information, registered domestic partner status, marital status, status as a crime victim, disability, protected veteran status, or any other characteristic protected by law. CyberCoders will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable state and local law, including but not limited to the Los Angeles County Fair Chance Ordinance, the San Francisco Fair Chance Ordinance, and the California Fair Chance Act. CyberCoders is committed to working with and providing reasonable accommodation to individuals with physical and mental disabilities. Individuals needing special assistance or an accommodation while seeking employment can contact a member of our Human Resources team at Benefits@CyberCoders.com to make arrangements.
Catering Lead
Leader job in Trenton, MI
At Panera, our people come first. If you're looking for a place where you can grow, feel supported, be yourself, enjoy great perks, and have a little fun along the way-you're in the right spot. We're here to help you succeed every day, in every way.
Get ready to rise and come join the funwhere you will be a part of making the familiar fantastic! Because at Panera, the best thing of bread is sharing it!
What's In It for You?
Competitive pay & eligible for team tips
Free on-shift meals & unlimited fountain beverages
Flexible & reliable scheduling
Paid vacation, sick time, and holidays for full-time team members
Medical, dental, vision, life insurance, pet insurance & 401(k) with match available
Career advancement & leadership development opportunities
Tuition discounts
Perks & rewards for team members
Team member assistance program
And much, much more!
As a Catering Lead at Panera, you play a crucial role in our catering operations. You help guests plan and choose delicious, familiar and fantastic Panera dishes for their events, respond to their inquiries and requirements, and guarantee hassle-free hosting with craveable food delivered promptly and accurately.
As a Catering Lead at Panera, Your Role Includes:
Manage and produce catering orders for our guests.
Create memorable experiences with warm, friendly service, effective communication, and proactive follow-ups to ensure every guest leaves satisfied.
Assist with delivering orders to guests' events.
Strictly adhere to health and food safety standards.
Maintain Panera's exceptional standards for craveable food quality.
Build excitement and interest in Panera's products and services.
Marketing Panera Catering to local area businesses, schools and events.
Assist and support your Managers and Team Members as needed.
Help build our Culture of warmth, belonging, growth, and trust.
This Opportunity Is for You If:
Minimum age: 18 years of age.
Complete basic food safety understanding and practice training. (Food Handler's Card, as required by law).
Enjoy people and have effective communication skills.
A self-starter who can meet goals with limited supervision.
Excellent organizational and time-management skills.
Must have your own vehicle that you can use for delivering orders and an acceptable driving record.
This role requires an individual that can safely operate a passenger motor vehicle and has an acceptable driving record.
This role requires flexible hours, including nights and weekends in a fast-paced environment with shifting priorities.
Ability to lift, carry, push, or pull objects 25-50 pounds.
Capability to stand and walk for up to 3 hours.
Must be able to clearly communicate and quickly understand guests and associates' directions in a loud environment.
Be an ambassador of our Guiding Values and Behaviors by making people smile, learning and growing together, finding solutions and taking initiative, working (and winning) as a team, having fun and celebrating success, and seeing the best in others!
__
Equal Opportunity Employer: Disabled/Veterans
Additional Description :
Team Leader Foreign Trade
Leader job in Detroit, MI
Your tasks
Establish processes to ensure the health of Brose's customs and foreign trade rules under a defined Trade Compliance Program
Liaison with customs officials, customer brokers, internal contacts
Procure services to support custom and foreign trade activities
Develop and monitor Foreign Trade Zone activities in the region. Define mitigation practices which could include legal precedence or opinion.
Establish best practices and opportunities for plants in the region
Provide Logistics strategies and guidance to minimize the financial impact related to tariffs on serial production and production equipment being imported
Identify and process PSC's or cost recovery under FTAs.
Ensure IMMEX compliance in Mexico supporting the Mexico Foreign Trade team
Monitor and administer compliance with relation to Foreign Trade Zones in the region
Develop based practice standards for the plants relating to programs such as C-TPAT
Establish processes for part classifications ensuring the integrity of the SAP system
Your Profile
Supply Chain Management, Transportation, Customs
Certified Customs Specialist (CCS)
Certified Export Specialist
Customs and Incoterm knowledge
Experience in foreign trade specifically relating to the automotive industry
Experience with financial transactions - invoicing, income statement, A/P, A/R
Experience with plant P&L; accrual process; SOFA reports
5+ years of experience in logistics or the supply chain management field.
Sanitation Team Leader (Supervisor) - 3rd Shift
Leader job in Macomb, MI
The Sanitation Team Leader (Supervisor) oversees all sanitation operations for plant equipment, machinery, and facilities. This role ensures compliance with safety, quality, and regulatory standards (OSHA, USDA, FDA, EPA) while leading a team responsible for cleaning, sanitizing, disassembling, and reassembling equipment. The Team Leader supports continuous improvement initiatives and ensures sanitation resources are available to meet production goals. This onsite position reports to the Macomb Plant Manager.
Shift Details:
3rd Shift: Monday to Friday, 5 PM - 3 AM; occasional Saturdays based on business needs.
Key Responsibilities:
Lead and supervise sanitation team to meet safety, quality, and efficiency goals
Ensure compliance with sanitation procedures and regulatory standards
Train and develop team members on cleaning chemicals, equipment, and safety protocols
Monitor sanitation performance and support process improvements
Enforce plant rules and safety programs (e.g., PPE, lockout/tagout, confined space)
Evaluate employee performance and provide coaching for improvement
Maintain documentation and support sanitation audits
Must Haves:
High school diploma or GED
2+ years of supervisory experience, preferably in manufacturing or food processing
Ability to work weekends and 3rd shift
Strong communication, problem-solving, and organizational skills
Proficient in Microsoft Office Suite (Outlook, Word, Excel, and Teams)
Travel: Minimal
Bonus Experience:
Bachelor's degree in related field
SAP experience
Knowledge of GMPs, sanitation procedures, and plant equipment
Food industry manufacturing experience
Familiarity with Listeria prevention and control strategies
Relocation assistance is available for this position. Preference will be given to local candidates.
#LI-Onsite
#LI-Associate
#LI-MW1
Compensation:
Pay Range:$59,000-$78,000
The annual salary listed above is the expected offering for this position. An employee's actual annual salary will be based on but not limited to: location, relevant experience/level and skillset, while balancing internal Conagra employees' equity. Conagra Brands will comply with applicable law regarding minimum salaries for exempt employees.
Our Benefits:
We care about your total well-being and will support you with the following, subject to your location and role:
Health: Comprehensive healthcare plans, wellness incentive program, mental wellbeing support and fitness reimbursement
Wealth: Great pay, bonus incentive opportunity, matching 401(k) and stock purchase plan
Growth: Career development opportunities, employee resource groups, on-demand learning and tuition reimbursement
Balance: Paid-time off, parental leave, flexible work-schedules (subject to your location and role) and volunteer opportunities
Our Company:
At Conagra Brands, we have a rich heritage of making great food. We aspire to have the most impactful, energized and inclusive culture in food. As a member of our 18,000+ person team across 40+ locations, you are empowered to reach your potential, make an impact and own your career. We're in the business of building champions - within our people and our iconic brands like Birds Eye , Slim Jim and Reddi-Wip .
Our focus on innovation extends beyond making great food, it also reflects our commitment to embracing new solutions that positively impact our team, the communities we serve and the health of our planet. Foodies Welcome.
Conagra Brands is an equal opportunity employer and considers qualified applicants for employment without regard to sex, race, color, religion, ethnic or national origin, gender, sexual orientation, gender identity or expression, age, pregnancy, leave status, disability, veteran status, genetic information and/or any other characteristic or status protected by national, federal, state or local law. Reasonable accommodation may be made upon request.
1st Shift Lead Process Technician - Injection Mold (Plastics)
Leader job in Brighton, MI
Job title: 1st Shift Lead Process Technician - Injection Mold (Plastics)
Shift: 7am to 3pm M-F with OT as needed
Reports to:
Operations Manager /Plant Manager
Job purpose:
To facilitate acceptable shift productivity and effectiveness while promoting a safe and positive working environment for all shift employees
Duties and responsibilities :
Direct supervision of all shift employees.
Using the production scheduling software , be able to schedule operators to specific work centers as well as manipulate scheduled production run information and create production schedules as needed through .
Complete shift employee performance evaluations monthly
Part file management / tool specific data management.
Pro Scan
Safe operation of typical material handling equipment such as a powered lift truck and pallet jack.
Troubleshoot molding defect causes and remedy any issue using a systematic approach to process changes.
Maintain clean, organized and safe work areas
Understanding and implementation of company goals and objectives
Understanding of the quality expectations of the parts molded
Review production schedule
Controls and monitors processes
Maintain part files and approved process'
Preventative tool maintenance
Prep for the next shift
Record downtime in QAD
Maintain tool PM log/lot folder
Load/unload tools from tool makers trucks (not shipping)
Fill out supervisors notes each day
Process monitoring log (twice per shift)
Install/remove paperwork (at MC)
Communicate with quality to ensure part quality
Basic robot operation
5S
Maintain the ISO9001-2015 - IATF 16949 pertinent to the production area
FIFO
Qualifications:
High School graduate
Excellent attendance
Positive Attitude
Prior experience as an injection molding process tech
Prior experience in a leadership role
Excellent communication skills
Excellent organizational skills
Basic mathematics skills
Safe working practices
Powered industrial lift truck driving experience
Computer skills
Job Type: Full-time
Pay: $25.00 - $28.00 per hour
Experience:
Manufacturing: 3 years (Required)
Ability to Commute:
Brighton, MI 48116 (Required)
Work Location: In person
Shift Leader - Taco Bell
Leader job in Washington, MI
At Taco Bell, We're hungry for
Más
.
Más
Heart,
Más
Flavor, and
Más
Value. If YOU want
Más
in YOUR life read on…
Are YOU a born leader? Do you want to lead people?
Do YOU make others smile easily?
When YOU say, “Thank You”, do you mean it?
Do YOU believe that everything is possible?
Are YOU a foodie? Do you know what it takes to make AWESOME food?
Are YOU proud when your team achieves success?
If YES, YOU have a career at Taco Bell!
Why NLI? Great People, Top Pay & Benefits, and Job Security, with an ever-expanding company providing opportunities for advancement to make a fulfilling career.
Apply for whatever reason guides you, stay for the work family you find!
At Northland Investments we don't just talk, we walk the talk. Maybe you're looking for extra cash, a reason to get out of the house, or you want to build a career but don't know where to start. We're here for all the above and we want to let you in on a "secret" - most of our District Managers, Directors, and even our President/Owner, they started as a Team Member with our Franchise! No joke, we grow from within and we're proud of it. Based in Northern Michigan for more than 30 years, we currently operate 29 restaurants throughout the state.
Visit **************** or text NEWJOB to 85000 today for a position that best fits YOU
Paid Vacation & Sick Time for All
Monthly Bonus Program
Health Insurance Packages - Medical/Vision/Dental
Referral Program - Work with Your Friends! (if you want to) $50/referral for you and the referred
401K with Employer Match
$$$ Daily Pay Subscriber
Tuition Scholarships and Grants available
Semi-Annual Reviews with Raise Potential
Flexible Schedules - We can work around you!
FREE meals every day you work
Recognition & Incentive Programs
Paid Training including your orientation
Education assistance FREE GED programs
Short-term disability & Life insurance
RSDS Discount Program - Cell Plans, Vacations, Apparel, and more
Fundraisers and volunteer programs
The Shift Manager assists the management team by leading work shifts and performing assigned administrative tasks. The Shift Manager directly supervises crew members; maintains responsibility for the performance of the assigned duties and is responsible for restaurant operations in the absence of the Restaurant General Manager. The Shift Manager accomplishes these objectives by actively leading, coaching and directing of crew on a day-to-day basis.
Shift Manager behaviors include:
Models and drives excellence in customer service
Models and maintains compliance with company standards in product and facility specifications
Models excellence in food handling procedures
Models excellence in operational activity to achieve unit guest service and performance targets
Assists in training, developing and motivating crew members
Assists in achieving store financial results by running a successful shift to brand standards
Event Team Lead
Leader job in Novi, MI
Bluecrew is seeking a Team Lead who will function as an extension of the Bluecrew Account Management team for large events, representing Bluecrew at the workplaces and leading a large number of Crew Members.
The Team Lead ensures success at customer locations, supports Crew Members onsite, and acts as a liaison between Bluecrew and the client.
As the Bluecrew onsite representative, we rely on the Team Lead to provide accurate timekeeping and share feedback from the workplace and Crew Members.
Experience required:
Minimum 10 jobs worked on the Bluecrew Platform
Previous experience in a leadership position
Ability to represent Bluecrew in a professional manner
Comfortable with all types of technology
Willing to use a personal cell phone/data plan to manage the workforce using the Bluecrew Manager App
Experience with conflict resolution
Flexible schedule
Available on weekends
Shift Responsibilities:
Check all CMs in via the check-in process and verify all employees are clocked in and accounted for via the Bluecrew manager app
Ensure all CMs are in the proper uniform and are physically/mentally ready to work
Delegate responsibilities to the CMs as instructed by the customer and assign them to their appropriate workstations
Check-in with CMs and the customer throughout the event to ensure everyone performs up to standard.
Conflict resolution - ensure CMs/customers respect one another and de-escalate situations when needed. In extreme cases, send the CM home and fill out an incident report for HR.
Coordinate the checkout process. Ensure all employees are clocked out and signed out (if needed), and answer any outstanding questions
Perform event general labor duties: event setup and teardown, maintain cleanliness of event space by picking up trash and disposing of waste properly, sweep/mop floors and walkways
***General Requirements***
Event Staff/Food Service
When working in Event Staff or Food Service Position through Bluecrew, you may be expected to do any and all of the following:
Working independently or in a team to cook, prepare, serve, or transport food items
Engaging with customers while operating a point of sale machine or cash register in a professional and courteous manner
Clean and sanitize dishes, utensils, cooking equipment, or other items at the start or end of your shift
Work on your feet, either stationary or constantly moving for the full shift
Reaching, crouching, bending over, and other physically strenuous activities at times, as required by the immediate supervisor
Comfortable working in a busy and at times hectic environment
There may be a specific dress code, but if it is not listed, please make sure to wear close-toed shoes and pants.
Note for that for any event staff position that requires handling food, you will need to follow GMP guidelines which include keeping your hair up, neatly trimmed fingernails, and you may be required to cover any facial hair.
It is important to Bluecrew that you go home in the same healthy state that you came to work in, so please do not accept this assignment if you cannot fulfill all of the above duties.
Lead, Part Time - The Village of Rochester Hills
Leader job in Rochester, MI
About Athleta For the past 25 years, we've committed ourselves and our brand to a single aim: to empower all women and girls. Inspiration. Collaboration. Connection. Inclusivity. It's what we do best, and we're on the hunt for people who share our passion for leading an active lifestyle, growing personally as well as professionally, and creating game-changing products and experiences.
We use business as a force for good by putting people and the planet right up there with profit, which is why Athleta is a certified B Corp. Ready to make a move? Join us. Because we know that alone we're strong, but together we're unstoppable.
About the Role
In this role, you will support the store leadership team by performing functional tasks as assigned. You will act as a role model to employees to support selling behaviors and the execution of tasks in specific areas of expertise. You will focus on leading processes, executing tasks, and maintaining productivity to ensure goals are met. Through collaboration with your leadership team, your goal is to role model and teach your team and drive behaviors to deliver a best-in-class customer experience.
What You'll Do
* Consistently treat all customers and employees with respect and contribute to a positive work environment.
* Promote customer loyalty by educating customers about our loyalty programs.
* All leads are expected to become experts of the brand's selling behaviors by role modeling these behaviors with every customer who walks through our doors and allowing us to provide an exceptional customer experience.
* Support sales leader during (non-peak) hours, with the customer as the primary focus
* Support the store leadership team by collaborating effectively with employees and ensuring work tasks are completed in a timely and efficient manner
* Build and share expertise in the product lifecycle
* Support completion of work before or after the store operating hours, inclusive of opening and/or closing checklists
* Leverage omni-channel to deliver a frictionless customer experience.
* Ensure all compliance standards are met.
Who You Are
* You embody Gap Inc's Purpose, Mission, Vision, Values and Behaviors
* Provides clear and direct communication of expectations.
* Ability to utilize technology effectively to engage with customers and team to meet goals
* Demonstrate interest and initiative towards continuous improvement and growth
* Agreeable to work a flexible schedule to meet the needs of the business, including holiday, evening, overnight and weekend shifts.
* Able to maneuver around the sales floor, stockroom and office and can lift up to 30 pounds.
Benefits at Athleta
* Merchandise discount for our brands: 50% off regular-priced merchandise at Old Navy, Gap, Banana Republic and Athleta, and 30% off at Outlet for all employees.
* One of the most competitive Paid Time Off plans in the industry.*
* Employees can take up to five "on the clock" hours each month to volunteer at a charity of their choice.*
* Extensive 401(k) plan with company matching for contributions up to four percent of an employee's base pay.*
* Employee stock purchase plan.*
* Medical, dental, vision and life insurance.*
* See more of the benefits we offer.
* For eligible employees
Gap Inc. is an equal-opportunity employer and is committed to providing a workplace free from harassment and discrimination. We are committed to recruiting, hiring, training and promoting qualified people of all backgrounds, and make all employment decisions without regard to any protected status. We have received numerous awards for our long-held commitment to equality and will continue to foster a diverse and inclusive environment of belonging. In 2022, we were recognized by Forbes as one of the World's Best Employers and one of the Best Employers for Diversity.
Site Lead
Leader job in Detroit, MI
Job Skills / Requirements
Crane IFS is a leading provider of janitorial services, dedicated to delivering exceptional cleaning solutions to our clients. We are currently expanding and looking for a professional to join our Janitorial Services division.
Built on a foundation of great brands and employees with a passion for service, our vision is to be the leading provider of essential services through empowered people, world-class customer service and convenient access. By joining our team, you'll be part of a talented network of employees with a shared vision.
Our environment is a diverse community where successful people work together to achieve common goals.
Job Position Description
The Site Lead plays a key role in supporting daily operations by setting the standard for cleaning quality, helping coordinate team activities, and acting as a first point of contact for staff. This position is hands-on and responsible for maintaining clean and healthy environments, while also serving as a resource and example to other team members. Duties include but are not limited to:
· Set the pace and example for cleaning standards, safety, and professionalism on-site
· Perform all cleaning duties for facilities using approved products, tools and procedures
· Use all cleaning equipment and products safely and effectively
· Sweeping, mopping, polishing, trash removal, restroom cleaning, windows, dusting, etc.
· Communicate supply needs and site conditions to the supervisor or manager
Physical Demands and Qualifications:
· Constant (up to 100%) standing, walking, pushing, kneeling, twisting, reaching
· Must be able to lift and/or carry up to 25lbs
· Must have a strong work ethic and willingness to learn
· The ability to be flexible and work at a fast pace in a multi-tasked job is a must
· Contribute to the overall team effort including being in uniform, dependable and on time
· The ability to pay close attention to small details
· The ability to read and write
· Treat all co-workers and customers with courtesy and respect
Apply and become a part of Crane IFS, one of the most respected professional cleaning companies in the country. We pride ourselves on creating cleaner and healthier environments for our customers, their employees and customers.
We offer online and hands-on training, an excellent work/life balance, opportunities for advancement, and a career path that matches your interests and goals.
Additional Information / Benefits
Benefits: Medical Insurance, Paid Vacation, Paid Holidays
This is a Full and Part-Time position
Cluster IT Multi-Site Leader
Leader job in Troy, MI
Hungry for challenges? Join a group with innovation at its heart and contribute to the automotive revolution!
OPmobility is a world-leading provider of innovative solutions for a unique, safer and more sustainable mobility experience. Innovation-driven since its creation, the Group develops and produces intelligent exterior systems, customized complex modules, lighting systems, clean energy systems and electrification solutions for all mobility companies. With a €11.4 billion economic revenue in 2023, a global network of 152 plants and 40 R&D centers, OPmobility relies on its 40,300 employees to meet the challenges of transforming mobility.
Our ambition? Provide automakers with cutting-edge equipment and solutions to develop tomorrow's clean and connected car.
This position is located in New Boston, MI.
Directly reporting to the Cluster IT Operations Manager for US & Canada, the Country IT Multi-site Leader for US & Canada:
Manages daily IT operations for a number of sites, cross-BG, ensuring the availability, performance, and reliability of local IT infrastructure and services.
Delivers hands-on L1 support for end-users, addressing hardware, software, and network connectivity issues, and serving as the first point of contact for local IT incidents and service requests.
Deploys IT policies, standards, and initiatives within the assigned scope.
Maintains compliance with IT security policies and standards, conducts regular security assessments, and implements measures to protect local IT assets and data.
Tracks and reports on key performance indicators (KPIs) related to IT operations and support, providing regular updates to country IT management.
Main activities include:
IT SITE INFRASTRUCTURE OPERATIONS MANAGEMENT
Oversee the daily IT operations at all sites within the assigned country or cluster.
Ensure the availability, performance, and reliability of local IT infrastructure and services.
Coordinate with local site managers to address IT needs and challenges
Manage and supervises hands-on L1 support for end-users, addressing issues related to hardware, software, and network connectivity.
Implement and maintains processes for effective monitoring, reporting, and continuous improvement of IT services within the region.
Ensure the Implementation and uphold of IT standards, policies, and best practices defined at a Group Level in his/her scope.
Ensure IT sites operate smoothly and without disruption, addressing any issues proactively to prevent major incidents and to maintain user satisfaction.
COLLABORATION AND COORDINATION
Supervise Local IT operations team for the assigned scope, providing direction, support, and professional development opportunities.
Coordinate with local business units to align IT services with business needs and priorities.
Promote continuous improvement actions.
PERFORMANCE AND MONITORING
Track and report on key performance indicators (KPIs) related to IT operations and support.
Provide regular updates to country IT management on the status and performance of local IT services.
Required profile and experience;
University degree or Engineering School with IT specialization or equivalent by experience.
Minimum of 5 years of experience in IT infrastructure management
Proficiency in IT service management, hardware and software troubleshooting, network administration, and IT infrastructure management.
Proficiency in the local language(s) of the assigned country or cluster, along with good command of English.
Experience with IT service management frameworks (e.g., ITIL).
Key behavioral competencies:
Customer focus, delivery, and result orientation.
Consistency and reliability. Ability to plan and organize activities efficiently.
Effective communication and interpersonal skills.
Proven leadership and team management skills
Teamwork, flexibility, and collaboration. .
Stong problem-solving and decision-making abilities.
As a responsible company, OPmobility pays particular attention to diversity and equality within its teams and the Group commits to treat all job applications equally.
Area Lead, Site of Care Rare Disease - Detroit, Michigan
Leader job in Detroit, MI
Career CategoryCorporate ServicesJob Description
Territory: Michigan, Great Lakes Area.
Join Amgen's Mission of Serving Patients
At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do.
Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas -Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.
Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
Area Lead Site of Care - Rare Disease
Live
What you will do
Let's do this. Let's change the world. In this vital role you will support treatment delivery for our infused therapy offerings within the gout, neuroimmunology, and ophthalmology business units. The position will be responsible for prospecting and establishing business-to-business relationships with local sites of care (SOC) and for developing and driving account/partner business plans that deliver on agreed upon objectives with oversight of SOC strategy development, execution and measurement. In addition, this individual will also be responsible for working with their internal partners to develop, implement and measure activities to increase pull through by coordinated business planning. Account responsibilities can include, but are not limited to, Local Infusion Providers and Specialty Pharmacies focused on Infusion Services.
Maximize site of care (SOC) opportunities in accordance with product labelling, strategic imperatives, and Company policies.
Provide overview of therapy and clinical procedures involved with infusion to assigned SOC customers/partners; coordinate with Medical Affairs team.
Identifying gaps in existing SOC networks, developing plans to expand SOC options.
Pulling through national partnership contracts at the local level.
Proactive and on-going access-related education including coding and billing and conducting quarterly business reviews with SOC administrative leaders.
Serve as the lead point of contact with sales, patient services and reimbursement access functions for assigned site of care (SOC) customers/partners.
Evaluate, develop, monitor, measure partnerships/business plans within the designated customer/partner accounts to align with defined objectives (profit, growth, value).
Responsible for developing and growing relationships with appropriate individuals within the accounts to meet the business needs of the customer/partner through a collaborative approach.
Develop and deliver business presentations/reviews to customers/partners based on mutual needs/benefits.
Develop business case to support contracts, negotiate and manage to ensure optimal results, if applicable.
Understand health care issues/strategies, customer issues/trends and best practices to establish credibility beyond product and therapeutic areas.
Co-develop and manage execution of jointly developed customer plans, holding customer and company accountable for plan execution.
Review and analyze contracted performance and communicate account performance broadly with key internal stakeholders.
Exercise sound judgment and oversight to ensure integrity and compliance with company policies in all activities and communications.
Adhere to relevant regulatory and compliance guidelines and Company policies.
Attend/staff/participate in meetings and/or conferences as requested by management.
The employee will be responsible for developing and implementing their own business plan.
Lead/contribute to special projects, as assigned, to drive operational performance improvements and enhance business opportunities.
Win
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The Site of Care professional we seek is a person with these qualifications.
Basic Qualifications:
Doctorate degree AND 2 years of Sales and/or Account Management experience
Or
Master's degree AND 4 years of Sales and/or Account Management experience
Or
Bachelor's degree or AND 6 years of Sales and/or Account Management experience
Preferred Qualifications:
Direct experience with identifying and activating sites of care in various infusion service areas such as:
-National and/or regional infusion service providers (ie; SPP's, Infusion Management Companies)
Hospital outpatient and infusion centers
Home infusion service providers
Individual buy and bill physician office practices
Experience in infused therapies required; rare disease experience preferred.
Rheumatology, Nephrology, Ophthalmology and/or endocrinology reimbursement experience preferred.
Recent launch experience with infused products preferred.
Ability to work independently and make decisions but with the knowledge of the situations where supervisory input is essential.
Strong understanding of healthcare regulatory and enforcement environments along with demonstrated integrity on the job.
Fosters innovation in account approaches and practices.
Strong attention to detail combined with a keen ability to recognize issues in the context of higher-level policies and regulations.
Excellent planning and organizational skills to work within date-sensitive deadlines.
Ability to work cross-functionally in a highly dynamic environment with a high sense of urgency.
Requires approximately 70% travel, including some overnight and weekend commitments.
Proficient in Microsoft Office.
Professional, proactive demeanor.
Strong interpersonal skills.
Excellent written and verbal communication skills.
ThriveWhat you can expect of us
As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we'll support your journey every step of the way.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:
A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models, including remote and hybrid work arrangements, where possible
Apply now and make a lasting impact with the Amgen team.careers.amgen.com
In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.
Application deadline
Amgen's application deadline for this position is 11/30; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
.
Salary Range
163,480.00 USD - 190,355.00 USD
Auto-ApplySite Leader for Mechanical Build
Leader job in Shelby, MI
At Paslin we are all about engineering excellence, innovation and vertical manufacturing competence. Our commitment to quality and excellence is evident in every project we undertake. Our team is passionate about automation powered by innovation!
We're looking for an experienced Machine Build Leader for our Site Installation team to lead the layout, installation, and modification of automated mechanical systems for advanced manufacturing equipment. This role is responsible to support the mechanical builders with leadership, training, and daily assignments.
If you're a strong communicator, a natural leader, and thrive in a fast-paced, safety-first environment, we want to hear from you. Bring your skills, attention to detail, and commitment to quality. Let's build something great together.
What We're Looking For
3+ years as a Senior Toolmaker or Senior Machine Builder
Journeyman's card or Technical Certification preferred
Prior experience as a team leader or supervisor is preferred
Background in integration of automated assembly systems with specific knowledge of mechanical and electrical build requirements. Weld systems knowledge is a plus.
Expertise in process improvement, lean manufacturing, and quality systems.
Ability to manage multiple priorities in a fast-paced environment.
Travel: This position requires flexibility to travel 80% to customer sites. During an installation project this role will require overnight travel to customer sites for periods of up to 12 days at a time over a period of multiple consecutive months. Must be able to travel to sites in USA, Canada and Mexico.
Work Environment: This position operates in both an office and a shop/plant environment, may be required to work at multiple facilities depending on workload.
Work type & Expected hours of work: Regularly works on-site at customer sites, returning back to a local Paslin location, either Hoover, 10-Mile or Cherry Creek. Must be flexible to work at any of these three locations as needed for an extended period of time. During critical phases of the project, work hours may flex up to more than 12 hours per day. This position is for regular, full-time work and may require coming in early, working late, or working on weekends to meet the needs of the business.
Physical Demands: The physical demands described are representative of those that must be met by an employee to successfully perform the essential functions of this job. While performing the duties of this job, the employee is regularly required to stand, walk, bend, and twist. Occasionally required to lift/push/pull up to 25lbs. This is a safety sensitive role, which includes working around moving equipment and machinery.
What's in It for You:
Competitive pay and great benefits. Paslin offers a wide range of benefits including Paid Time Off, Paid Holidays, 401k Match, Medical, Dental, Vision, Accident, and Life Insurance.
A chance to improve your skills and your career. Paslin believes in investing in people and offers a variety of development programs with excellent opportunities for individual growth through training, tuition reimbursement, and career advancement.
A supportive, collaborative team and a fun, engaging work environment. Check out our company page on LinkedIn to learn more about our values and see how we give back to our community.
Paslin is an Equal Opportunity Employer: It is our policy to provide equal employment and advancement opportunities to all employees and applicants without regard to race, sex (including pregnancy and conditions related to pregnancy), color, ancestry, national origin, gender, sexual orientation, marital status, weight, height, religion, age, physical or mental disability, gender identity, results of genetic testing, AIDS, HIV, misdemeanor arrest record (not resulting in a conviction), military veteran status or any other characteristic protected by local, state, or federal law. Paslin utilizes a consumer reporting agency to obtain consumer reports as defined by the Fair Credit Reporting Act.
Auto-ApplySr. Technical Lead - CPQ
Leader job in Novi, MI
Title: Sr. Technical Lead - CPQ Pioneer the next generation of innovation. Join us and you'll develop your skills and expertise to the very highest levels, working in an international environment for a company known the world over for its brilliance. Key Accountabilities:
* Lead and govern Configure-Price-Quote (CPQ) solution architecture and design, ensuring alignment with business requirements and IT standards
* Collaborate with solution providers to support and enhance CPQ solutions across multiple countries
* Partner with the business product owner to prioritize and manage potential backlog
* Deliver and maintain scalable, sustainable, and cost-effective technical solutions by working with partners
* Identify and implement functional improvements and continuous enhancements by working with partners
* Provide final authorization for transport requests to QA and production systems
* Review and approve technical change documents, Blueprint Solution Documents (BSD), and system documentation
* Facilitate process standardization from a technical perspective
* Escalate missing inputs, resource constraints, or timeline risks to Project Management
* Actively contributes to development work for the first 6 months (e.g., working on user stories, writing and reviewing code) to ensure solution quality and vendor accountability
* Lead and delegate tasks effectively within a team environment, ensuring timely delivery
* Actively leverage RRPS-provided GenAI solutions to improve productivity and solution quality daily
* Promote a safety and compliance culture in area of responsibility, and live the letter and the spirit of the Rolls Royce Code of Conduct
* Perform special assignments as required
Basic Requirements:
* Applicants must be authorized to work for any employer in the U.S without sponsorship. We are unable to sponsor or take over sponsorship of an employment Visa at this time
* Bachelor's Degree in Information Technology, and 5 years functional support experience with CPQ solutions; or 9 years of CPQ functional support experience.
* Available to work flexible hours, including nights and weekends, when necessary
* Travel - domestic and international (20% short notice)
Preferred Qualifications:
* Subject-Matter Expert with CPQ solutions and hands-on participation in various phases of implementation.
* Excellent knowledge and DevOps experience in a Microsoft on-premises and Azure Environment
* Excellent organizational, planning, and follow up skills
* Excellent analytical and problem-solving skills
* Excellent presentation skills
* Good knowledge of IT Service Management (ITSM) processes and system ownership responsibilities
* Strong oral and written communication skills
* Strong interpersonal skills
* Strong ability to work independently and with others
* Experience configuring Cincom CPQ
* Experience in integration with Enterprise PLM and ERP Solutions
* Background in manufacturing or power generation environments
Rolls-Royce is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to any protected characteristics.
At Rolls-Royce, we are committed to creating a workplace where all employees feel respected, supported, and empowered to do their best work. We foster a welcoming and innovative work environment that invests in you, giving you access to an incredible breadth and depth of opportunities where you can grow your career and make a difference.
Job Category
Information Technology
Job Posting Date
18 Nov 2025; 00:11
Pay Range
$90,985 - $136,477-Annually
Location:
Mankato, MN
Benefits
Rolls-Royce provides a comprehensive and competitive Total Rewards package that includes base pay and a discretionary bonus plan. Eligible employees may have the opportunity to enroll in other benefits, including health, dental, vision, disability, life and accidental death & dismemberment insurance; a flexible spending account; a health savings account; a 401(k) retirement savings plan with a company match; Employee Assistance Program; Paid Time Off; certain paid holidays; paid parental and family care leave; tuition reimbursement; and a long-term incentive plan. The options available to an employee may vary depending on eligibility factors such as date of hire, employment type, and the applicability of collective bargaining agreements.
Auto-ApplyConstruction Site Lead - Inground Pool Installation
Leader job in Village of Clarkston, MI
Job DescriptionBenefits/Perks
Flexible Schedule
Competitive Pay
Career Advancement
We are seeking a hardworking and reliable Construction Site Leader to join our team. In this role, you will coordinate with on-site manager to oversee each of the project tasks for the in-ground pool installation and ensure they progress on schedule. The ideal candidate is will lead the team to complete all steps in each construction projects.
Responsibilities
Manage weekly tasks and projects based on the stage of construction of the pool
Coordinate with the on-site manager to complete tasks, this can be over multiple projects
Ensure all team members on site comply with building and safety regulations
Report out key deliverables and milestones and ensure progress is being made
Coordinate subcontractors and outside contractors when on-site
Supervise and direct laborers
Identify and mitigate any potential issues that may arise
Qualifications
Work site experience leading teams
Understanding of construction methods and processes
Knowledge of construction methods, building products, and building codes
Strong leadership and crisis resolution skills
Ability to break large projects into small steps
Site Leader
Leader job in Warren, MI
TRIGO Global Quality Solutions is seeking to fill a Site Leader Position in Warren, MI. The starting rate of pay is $18 per hour. Overall Purpose of a Site Leader Ensure Quality services and support for all missions assigned to their site(s) Provide leadership and guidance to personnel fulfilling missions
Support and maintain a positive and productive atmosphere at sites
Ensure all company and customer guidelines are being upheld
Reports to
Site Manager / Site Supervisor
Responsibilities
Client relationship & Business development
* Establishing and maintaining relationships with customers and site personnel
* Daily communications with various stakeholders at the site level
Operations
* Set up and supervise missions
* Staffing of missions
* Training and validate inspectors
* Coordinate changes in missions
* Isolate, tag and verify nonconforming material
* Conduct ongoing audits of effectiveness of work being performed
* Perform visual, mechanical, and functional verifications to ensure compliance to quality standards and specifications
* Make independent judgments for subjective scenarios.
* Work as an inspector when required
* Demonstrates commitment to reduce the risk of workplace accidents
* Must comply with local and company Health & Safety legislation, laws, and policies
Organization & management
* Ensures all site personnel receive corporate communications
* Partner with Human Resources for performance and attendance issue resolution
* Act as a liaison between Site Manager and inspectors
* Ensure all inspector time is entered, monitored and approved
* Create and maintain a 5S working environment
Technical
* Update daily system entries in company and customer portals
* Create and maintain customer and company reports
* Utilize company web portals to record required audits and documentation
* Troubleshoot and problem solve with the supplier and customer for issues pertaining to process flow, new criteria, spikes/spills
* Create electronic work instructions and have the ability to navigate company and customer websites and portals
Other
* Any other duties as assigned
Knowledge, skills, abilities
Hard Skills
* Proficiency in English
* Computer skills Microsoft Office (basic Microsoft Excel proficiency) and Outlook
* Proficient in the use of various gauges and measuring devices
* Ability to lift / move 50 lbs.
Values and Attitude
Global team spirit
* Team player
* Caring for people
* Open-minded
Excellence
* Reactive
* Resilient to pressure
* Rigorous
Customer focus
* Client oriented
* Reliable & trustworthy
* Flexible
Initiative
* Autonomous
* Innovative
* Daring
Work experience
Overall recommendations
* 1+ years of work experience in a supervisory role preferred
* 1+ year in Quality related position preferred
Education background
Overall recommendations
* High School Diploma or Equivalent
About TRIGO Global Quality Solutions
Founded in 1997, TRIGO is a multinational company providing operational Quality Management solutions for the manufacturing sector, especially in the automotive and aerospace industries. With a team of more than ten thousand professionals present in 20+ countries across 4 continents, TRIGO offers a comprehensive portfolio of Quality Assurance services ranging from inspection to expert auditing, consulting and training.
The unrivaled expertise, industrial mindset and extensive global footprint that TRIGO has built up over the last 3 decades has made TRIGO the leading quality solutions provider using the latest innovative and reliable digital systems and standard processes, delivering results in the most demanding industries. TRIGO has recently started to expand its clientele by offering quality services to the medical, chemical and food industries.
TRIGO Global Quality Solutions is committed to the core values of equal employment opportunity. We are committed to treating people fairly, and with respect and dignity. We offer employment opportunities based upon an individual's qualifications and performance, free from discrimination or harassment because of race, ancestry, place of origin, ethnic origin, color, citizenship, creed, sex, sexual orientation, age, marital status, family status, and disability.
TRIGO Global Quality Solutions appreciates receiving all expression of interest; however, only those candidates invited for an interview will be contacted.
Site Leader
Leader job in Warren, MI
TRIGO Global Quality Solutions is seeking to fill a Site Leader Position in Warren, MI. The starting rate of pay is $18 per hour.
Overall Purpose of a Site Leader
Ensure Quality services and support for all missions assigned to their site(s)
Provide leadership and guidance to personnel fulfilling missions
Support and maintain a positive and productive atmosphere at sites
Ensure all company and customer guidelines are being upheld
Reports to
Site Manager / Site Supervisor
Responsibilities
Client relationship & Business development
Establishing and maintaining relationships with customers and site personnel
Daily communications with various stakeholders at the site level
Operations
Set up and supervise missions
Staffing of missions
Training and validate inspectors
Coordinate changes in missions
Isolate, tag and verify nonconforming material
Conduct ongoing audits of effectiveness of work being performed
Perform visual, mechanical, and functional verifications to ensure compliance to quality standards and specifications
Make independent judgments for subjective scenarios.
Work as an inspector when required
Demonstrates commitment to reduce the risk of workplace accidents
Must comply with local and company Health & Safety legislation, laws, and policies
Organization & management
Ensures all site personnel receive corporate communications
Partner with Human Resources for performance and attendance issue resolution
Act as a liaison between Site Manager and inspectors
Ensure all inspector time is entered, monitored and approved
Create and maintain a 5S working environment
Technical
Update daily system entries in company and customer portals
Create and maintain customer and company reports
Utilize company web portals to record required audits and documentation
Troubleshoot and problem solve with the supplier and customer for issues pertaining to process flow, new criteria, spikes/spills
Create electronic work instructions and have the ability to navigate company and customer websites and portals
Other
Any other duties as assigned
Knowledge, skills, abilities
Hard Skills
Proficiency in English
Computer skills Microsoft Office (basic Microsoft Excel proficiency) and Outlook
Proficient in the use of various gauges and measuring devices
Ability to lift / move 50 lbs.
Values and Attitude
Global team spirit
Team player
Caring for people
Open-minded
Excellence
Reactive
Resilient to pressure
Rigorous
Customer focus
Client oriented
Reliable & trustworthy
Flexible
Initiative
Autonomous
Innovative
Daring
Work experience
Overall recommendations
1+ years of work experience in a supervisory role preferred
1+ year in Quality related position preferred
Education background
Overall recommendations
High School Diploma or Equivalent
About TRIGO Global Quality Solutions
Founded in 1997, TRIGO is a multinational company providing operational Quality Management solutions for the manufacturing sector, especially in the automotive and aerospace industries. With a team of more than ten thousand professionals present in 20+ countries across 4 continents, TRIGO offers a comprehensive portfolio of Quality Assurance services ranging from inspection to expert auditing, consulting and training.
The unrivaled expertise, industrial mindset and extensive global footprint that TRIGO has built up over the last 3 decades has made TRIGO the leading quality solutions provider using the latest innovative and reliable digital systems and standard processes, delivering results in the most demanding industries. TRIGO has recently started to expand its clientele by offering quality services to the medical, chemical and food industries.
TRIGO Global Quality Solutions is committed to the core values of equal employment opportunity. We are committed to treating people fairly, and with respect and dignity. We offer employment opportunities based upon an individual's qualifications and performance, free from discrimination or harassment because of race, ancestry, place of origin, ethnic origin, color, citizenship, creed, sex, sexual orientation, age, marital status, family status, and disability.
TRIGO Global Quality Solutions appreciates receiving all expression of interest; however, only those candidates invited for an interview will be contacted.
IT Platform Systems Team Lead
Leader job in Sterling Heights, MI
The Platform Systems Team Lead's role is to oversee the development, implementation, and maintenance of IT platforms, with a specific focus on VMWare, Azure, Windows Server, and Active Directory management. This role requires a strategic thinker with deep technical knowledge. The lead will ensure enterprise platform provisioning and maintenance that is consistent with company goals, industry best practices and regulatory requirements.
Company Information:
General Dynamics is a successful Fortune 100, global aerospace and defense company, with over 90,000 employees world-wide. General Dynamics Land Systems, a business unit of General Dynamics, has a strong foundation of delivering core engineering and manufacturing capabilities to our clients for military vehicles. Our team is focused on continuous process and productivity improvements that reduce product costs, while increasing troop safety and effectiveness. Land Systems continues to work with the US Armed Forces and its Allies to ensure these vehicles remain survivable, relevant, flexible, affordable and capable of addressing a dynamic threat environment.
What We Offer:
Starting your career or you are an experience professional, we offer a Total Rewards package that is Impactful and built for you.
* Healthcare including medical, dental, vision, HSA and Flex Spending
* Competitive base pay and incentive pay that rewards individual and team performance, and comprehensive benefits.
* 401k Match (6%)
* Educational Assistance
* 9-80 Work Schedule (This position's standard work schedule is a 9/80. The 9/80 schedule allows employees who work a nine-hour day Monday through Thursday to take every other Friday off)
* On-going learning opportunities within a diverse, inclusive and rewarding work environment
* Onsite cafeteria, fitness center, and outdoor fitness track
Responsibilities to Anticipate/Expect:
Strategy & Planning
* Develop and maintain capacity plans and long-term strategic goals for server systems and software in conjunction with end-users and department managers.
* Implement automation that will maximize the team's time and reduce errors.
* Actively mentor and guide systems administrators.
* Make recommendations on technology improvements and asset refresh strategies.
Acquisition & Deployment
* Coordinate with network engineering, business application, and database administration functions to procure and implement systems that utilize industry best practices to meet corporate objectives.
* Participate in negotiations with vendors, outsourcers, and contractors to secure software products and services.
Operational Management
* Ensure the team's work is equitably distributed based on skills and interests.
* Manage all operating systems and supporting applications.
* Ensure runbooks and documentation are current, complete, and peer reviewed.
* Manage and report on utilization and capacity of assets.
* Manage end user accounts, permissions, access rights, and storage allocations in accordance with best-practices regarding privacy, security, and regulatory compliance.
* Establish, document, and test routine system backups and restores.
* Anticipate, mitigate, identify, troubleshoot, and resolve hardware and software problems on systems. Escalate incidents as necessary.
* Support application development teams throughout project lifecycles.
* Analyze system, server, application, storage, and backup device performance.
* Recommend, schedule, and perform software and hardware improvements, upgrades, patches, reconfigurations, and/or purchases.
* Develop, document, and maintain policies, procedures and associated training plans for system administration and appropriate use.
* Manage and provide guidance to members of the team.
Position Requirements:
Formal Education & Certification
* Bachelors of Science degree in Computer Science, Management Information Systems, or related is preferred. Experience will be considered in lieu of degree.
* 10+ years of experience as a Windows server administrator
* Expertise with Active Directory.
* Certifications in Microsoft solutions, VMWare, Authentication, virtualization.
Knowledge & Experience
* Experience in managing a team and ensuring crossover of knowledge and capabilities.
* Background in automating routine processes such as patching and group management.
* Deep technical background with expertise in VMWare, Azure, Windows Server, and Active Directory management and automation tools.
* Strong knowledge of local area network administration.
* Experience documenting and maintaining configuration and process information.
* Good understanding of the organization's goals and objectives.
* Knowledge of applicable regulatory requirements.
* Skilled at working within a team-oriented, collaborative environment.
* Experience working with outside vendors.
* Background in defense industry with experience deploying systems that meet regulatory requirements is a plus
Personal Attributes
* Strong interpersonal skills with a team mentality.
* Customer service orientation.
* Proven analytical and problem-solving abilities.
* Ability to effectively prioritize and execute tasks in a high-pressure environment.
* Ability to present ideas and solutions in user-friendly language.
* Must be a U.S. Person (i.e. a lawful permanent resident of the U.S.)
GDLS considers factors such as, scope/responsibilities of the position, candidate experience and education/training background, in addition to local market comparable and business considerations when extending an offer.
Headquartered in Reston, Virginia, General Dynamics is a global aerospace and defense company offering a broad portfolio of products and services in business aviation; ship construction and repair; land combat vehicles, weapons systems and munitions; and technology products and services. General Dynamics employs more than 100,000 people across 65 countries worldwide and in all 50 U.S. states, more information is available at *********** General Dynamics Land Systems, is a business unit of General Dynamics, and is an innovative leader of ground combat systems' equipment and software for our clients. Our performance-driven team partners with the U.S. Army, U.S. Marine Corp and other militaries across the Globe to ensure that next generation ground combat vehicles are ready to protect our fighting men and women in uniform. General Dynamics Lands Systems provides a competitive compensation package, site specific flexible work schedules, 401(k) with Company Match; Bonus Eligibility, Employee Development Opportunities, Tuition Reimbursement, On-site Amenities, and comprehensive Medical/Dental/Vision Insurance.
As an Equal Opportunity Employer, General Dynamics Land Systems ("GDLS") provides all persons with equal opportunity and access to all aspects of employment process, without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, marital status, age, disability, status as a protected veteran, or membership in any group protected by federal, state, or local anti-discrimination laws. GDLS also is committed to providing reasonable accommodations to individuals with disabilities and disabled veterans.. If, due to a disability, you need an accommodation to search or apply for an opportunity with GDLS, please call ************ or send an e-mail to ***************** for assistance and let us know the nature of your request and your contact information.
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PK/PD Modeling / Pharmacometrics Lead
Leader job in Sterling Heights, MI
This person complements the client's “Translational / Clinical Pharmacology Decision-Maker” team by grounding dose selection and exposure-response analysis in **quantitative structure and parameter plausibility**.
### **Who we're looking for** - Deep hands-on experience in **PK, PD, exposure-response modeling**, and ideally **population PK or QSP**. - Expert at model fitting, sensitivity analysis, and identifying non-plausible parameter spaces. - Can evaluate the validity of dose-exposure predictions and detect high-risk extrapolations. - Comfortable designing **model evaluation rubrics** that distinguish between acceptable vs. non-credible outputs. - Able to articulate how quantitative checks should complement narrative decision logic. **Nice-to-have:** - Experience supporting translational or clinical pharmacology leads in dose justification. - Familiarity with integrating nonclinical PK/PD data (2-species GLP → human FIH extrapolation). ### **Experience level** - ~8-12 years of quantitative pharmacology experience in **pharma, CROs, or modeling consultancies**. - Strong portfolio in **population PK/PD**, **exposure-response**, and **parameter estimation** using NONMEM, Monolix, or equivalent tools. - Demonstrated ability to interpret model results for decision-making, not just fit data. - Can create **fit-for-purpose models** and critique model structures or assumptions under uncertainty. ### **Expectations** - Design and refine **micro-evaluations** for PK/PD performance (curve fits, parameter checks, error taxonomies). - Encode **quantitative sanity checks** into model rubrics for automated evaluation. - Define **failure conditions** (e.g., unsafe extrapolation, poor coverage curves, invalid assumptions). **Inputs we give:** - PK/PD datasets, tox summaries, and performance prompts (e.g., “fit exposure-response curves, interpret safety margins”). - Example model outputs from automated systems. **Expected outputs:** - **Quantitative Rubrics:** clear thresholds for acceptable parameter fits, coverage curve quality, and model integrity checks. - **Golden Fit Examples:** representative “ideal” PK/PD model outputs and visualizations for calibration. - **Error Taxonomy:** structured list of typical modeling or fitting errors, with root-cause annotations. - **Meta-Layer Commentary:** short note per rubric capturing how expert modelers recognize implausible or unsafe fits beyond numeric error values. ### **Engagement Model & Compensation** - **Contract / part-time**, remote, outcome-based deliverables.
Shift Leader
Leader job in Imlay City, MI
As a Shift Leader, you will be responsible for supervising, training and motivating Team Members, stocking and maintaining required inventory levels, cash handling and preparation of reports and maintaining a clean and safe work environment. Duties will also include various customer service activities and preparation of product. A qualified applicant must be 18 years of age, have a high school diploma or GED, have a valid driver's license with access to a personal vehicle, with secure, dependable and reliable transportation in order to make deposits. Excellent communication skills, management/leadership and organizational skills are required, as well as the ability to move up to 35 pounds from one area to another.