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After Doctor Hofmann first discovered its effects in 1943, LSD quickly became recognized for its possible therapeutic effects.
In 1947, Sandoz began selling LSD under the name Delsid, essentially marketing it as a cure-all for conditions ranging from alcoholism to schizophrenia.1 Extensive research on LSD began and continued for the next few decades.
In 1951 in Pont-Saint-Esprit, France, there was another such episode in which either ergot or LSD was implicated.
During a secret CIA meeting in 1953, Doctor Frank Olson, a bioweapons expert, received a drink spiked with LSD. Later, Olson developed symptoms that caused him to seek psychiatric treatment in New York, accompanied by a CIA doctor with whom he shared a hotel room.
In 1960, California-based writer Ken Kesey volunteered for one of the CIA’s LSD experiments at a hospital.
The operation ceased in 1964 because LSD was determined to be too dangerous to use.8
In 1967, the journal Science published a study that claimed human blood cells placed in an LSD culture underwent chromosomal breakage.
In response to growing crime rates and an expanding drug culture, President Richard Nixon signed the Comprehensive Drug Abuse Prevention and Control Act into law in 1970.
However, an updated report in 1971 in the same journal explained that “ingesting moderate doses of LSD caused no detectable genetic damage.”13, 14
In the 2016 National Survey on Drug Use and Health, 8.3% of young adults age 18-25 reported using LSD at least once in their lives, with 3.4% reporting use in the past month.
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