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Research Fellow jobs at Massachusetts General Hospital

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  • Postdoctoral Research Fellow

    The General Hospital Corporation 4.7company rating

    Research fellow job at Massachusetts General Hospital

    Site: The General Hospital Corporation Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. Job Summary The Vazquez-Garcia Lab, part of Massachusetts General Hospital, Harvard Medical School, and the Broad Institute, is seeking exceptional candidates for a postdoctoral position in our interdisciplinary team. Our lab investigates the fundamental principles of somatic evolution and immune surveillance in cancer. We use data-driven approaches to study cellular dynamics in tumors, combining AI/ML, single-cell genomics, and cellular imaging approaches with large clinical datasets and experimental models. Our research draws on multi-modal data from basic science and clinical practice to understand how genomic adaptations confer selective advantages to tumor cells, act as biomarkers of therapeutic response and resistance, and sensitize tumors for targeted intervention. Our ultimate goal is to impact human health and clinical care for patients, leveraging our understanding of cancer trajectories to enable biomarkers and therapeutic strategies that anticipate and overcome tumor progression. You will join a highly collaborative and interdisciplinary group committed to tackle challenging problems in computational oncology. You will work on independent research projects within the lab, and actively collaborate with colleagues across MGH, HMS, the Broad Institute and other institutions. You will be part of a vibrant scientific community and will have access to state-of-the-art computational resources and high-throughput genomics technologies. The main responsibilities will include but not be limited to: ● Design, train, and evaluate cutting-edge AI and statistical models using large patient datasets. ● Build robust pipelines for large-scale data processing and benchmarking across modalities. ● Collaborate closely with cancer biologists, clinicians, and other computational researchers to generate testable hypotheses and interpret findings. ● Perform exploratory research in a fast-paced setting with the potential for real impact on patients. ● Contribute to the development of high-quality, reusable, open-source software. ● Publish research in top-tier journals and present at major conferences. ● Help foster a collaborative lab environment by advising and supporting junior team members. Qualifications Minimum qualifications: Ph.D. (or near completion) in a relevant field such as Computational Biology, Computer Science, Physics, Mathematics, Statistics, or a related quantitative discipline. Demonstrated proficiency in Python, R and/or other scientific computing languages. Proven track record of productivity through peer-reviewed publications. Excellent written and verbal communication skills. Ability to work independently and as part of a collaborative team. Strong organizational skills and attention to detail. Preferred experience: Proven experience working with high-dimensional, multi-modal omics data and clinical data. Strong background in advanced statistical modeling and/or modern machine learning approaches (e.g. transformers, foundation models, generative modeling, interpretable AI). Knowledge of cancer biology, immunology, or molecular biology. Familiarity with cloud computing and workflow management (e.g., Nextflow, Snakemake). Experience with version control and software engineering practices. Interest in contributing to open-source bioinformatics software. To apply, please submit a CV, representative publications or preprints, a statement of prior research and future interests, and contact information for three references to Ignacio Vazquez-Garcia, PhD at *******************************. Learn more: ***************************************** Additional Job Details (if applicable) Remote Type Onsite Work Location 149 Thirteenth Street Building 149 EEO Statement: The General Hospital Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at **************. Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
    $45k-57k yearly est. Auto-Apply 60d+ ago
  • Postdoctoral Research Fellowship - Medical Artificial Intelligence

    The General Hospital Corporation 4.7company rating

    Research fellow job at Massachusetts General Hospital

    Site: The General Hospital Corporation Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. Job Summary Please email all materials to the Fellowship Director, Roger Dias, MD, PhD, MBA at ********************* by July 31st, 2025. The Neil and Elise Wallace STRATUS Center for Medical Simulation is committed to advancing medical education, patient safety, and healthcare outcomes through cutting-edge applications of medical simulation technologies supported by innovative curricula, contemporary educational methodologies, continuous improvement, and rigorous, multidisciplinary research. At STRATUS, the Medical AI & Cognitive (MAICE) Lab, led by Dr. Roger Dias, MD, PhD, MBA, brings together a multidisciplinary team of clinicians, engineers, psychologists, computer scientists, and educators, including collaborations with several scientists and institutions, nationally and internationally. The core mission of our research lab involves the use of cutting-edge technologies to objectively measure and improve clinicians' performance, with the ultimate goal of enhancing patient safety and improving clinical outcomes. Our projects have been funded by NASA, NIH, DoD, and NSF, leveraging machine learning and artificial intelligence to support high-performance clinical care in a variety of settings, including emergency medicine, critical care, surgery, space, and military medicine. The Postdoctoral Fellowship in Medical AI is intended for graduates of doctoral programs in Science, Technology, Engineering, and Mathematics (STEM) with a solid foundation in applying advanced ML/AI techniques to tackle complex problems in healthcare. The program is ideal for early-career scientists seeking additional experience in the healthcare field, as well as opportunities to apply AI/ML technologies and software engineering to improve patient care and safety. The research fellow will be mentored by a multidisciplinary team of experts, allowing her/him to gain extensive knowledge and experience in diverse research areas including medicine, human factors, cognitive science, behavioral sciences, and aerospace and military research. The successful candidate will conduct research and development within the emerging field of medical AI, applying advanced programming and software engineering skills. The research fellow will design and develop software architectures and train and evaluate ML/AI models to create AI-based solutions and integrate them with large multi-source clinical databases, including time-series physiological data, demographics, behavioral and psychological assessments, video, audio, electronic health records (EHR), and clinical performance outcomes. The fellow will also develop AI-based medical simulation applications and real-time clinical decision support systems. Qualifications Required: All applicants must have a Ph.D. in a STEM discipline, with extensive knowledge, skills, and demonstrated experience in software development, AI/ML modeling and evaluations. These are the required qualifications: Proficiency in Python and/or C++ Familiar with signal processing and time series analysis Familiar with cloud computing services and API Demonstrated experience with AI/ML training and model evaluations, including neural networks and/or large language models Demonstrated experience with TensorFlow and/or PyTorch and/or Scikit-learn Demonstrated prior experience in applying AI/ML in the medical field Demonstrates research experience as lead author in peer-reviewed scientific publications Preferred: Previous experience with computer vision (e.g., convolutional neural networks) and/or visual language models Salary and Benefits The selected candidate will be appointed for two years, with the opportunity to renew the appointment for a third and/or fourth year pending performance review and funding. Salary will be commensurate with experience, based on BWH guidelines for postdoctoral trainees. Benefits include comprehensive health insurance, optional dental, vision, and retirement plans, and reimbursement for conference travel related to fellowship projects. BWH is a Harvard-affiliated Teaching Hospital, and the research fellow with be eligible for an appointment at Harvard Medical School. The following items are considered in the application process: 1. Current CV 2. Recent work sample (e.g., peer-reviewed manuscript, pre-print, GitHub code, software demo) 3. At least three peer-reviewed publications in which the candidate was a significant contributor 3. Candidates selected for an interview will be asked to submit two letters of recommendation. Application materials & queries should be emailed to: Roger Dias, MD, PhD, MBA at ********************* Director of Research & Innovation Associate Professor of Emergency Medicine, Harvard Medical School Additional Job Details (if applicable) Remote Type Hybrid Work Location 10 Vining Street EEO Statement: The General Hospital Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at **************. Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
    $48k-65k yearly est. Auto-Apply 60d+ ago
  • Postdoctoral Research Fellow - McGraw/Patterson Center

    Dana-Farber Cancer Institute 4.6company rating

    Boston, MA jobs

    **Postdoctoral Fellowship in Cancer Screening, Early Detection, and Cancer Interception** **Dana-Farber Cancer Institute, Department of Medical Oncology, Division of Population Sciences** The Dana-Farber Cancer Institute, Department of Medical Oncology, Division of Population Sciences, seeks a highly motivated postdoctoral fellow in the McGraw/Patterson Center for Population Sciences. The Center is committed to population-based research aimed at detecting cancer early, preventing cancer at the community level, identifying and evaluating cancer risk in high-risk populations, and measuring the quality and outcomes of cancer therapy. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. We invite applications for a fellowship focused on **epidemiological and clinical studies of cancer screening, early detection, and cancer interception** , with particular emphasis on **multi-cancer early detection (MCED)** approaches and **novel cancer screening strategies** being evaluated in large-scale clinical trials. The fellow will work under the mentorship of Drs. Elizabeth O'Donnell, MD, and Catherine Marinac, PhD, who oversee a research program focused on identifying and testing innovative cancer screening technologies and biologically informed interventions to prevent and intercept cancer. Areas of research may include: + Evaluation of multi-cancer early detection tests and implementation strategies in clinical and population settings + Development and testing of biomarkers of early cancer and precancerous states + Cancer interception studies aimed at identifying biological and behavioral targets for preventing progression from premalignant to invasive disease + Integration of lifestyle, metabolic, and genomic data to refine early detection and prevention strategies + Disparities research and risk modeling to optimize equitable deployment of new cancer screening modalities The fellow will have opportunities to lead analyses within ongoing and newly developed clinical trials, contribute to manuscript preparation and grant development, and design independent projects aligned with the lab's research portfolio. Interested candidates should submit an electronic copy of their **curriculum vitae** and a **cover letter** describing their research experience, interests, and career goals. + Candidates should hold a doctoral degree in **epidemiology, biostatistics, genetics/genomics, public health, or related fields** . + MD candidates with a strong research background will also be considered. + Multidisciplinary training and experience across epidemiologic, clinical, and molecular research domains is desirable. + Prior experience in large cohort or clinical trial data analysis is advantageous. **Pay Transparency Statement** The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications. For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA) $72,000 - $76,385 At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply. Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law. **EEOC Poster**
    $72k-76.4k yearly 51d ago
  • Postdoctoral Research Fellow - Reinherz Lab

    Dana-Farber Cancer Institute 4.6company rating

    Boston, MA jobs

    The Reinherz lab at Dana-Farber Cancer Institute and Harvard Medical School is recruiting a postdoctoral fellow to study HIV-1 vaccine immunology. We use an interdisciplinary approach combining structural biology, molecular biology, biochemistry, and immunology to generate insights that can be translated into HIV-1 vaccine design. Specific research areas of interest include molecular and cellular mechanisms underlying B cell immunodominance and strategies to modulate B cell affinity maturation during vaccination to induce protective immunity while preventing induction of autoimmunity. The laboratory provides a rich training environment and access to cutting-edge techniques. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. The postdoctoral fellow will work on HIV-1 env vaccine development and modulation of B cell affinity maturation. He or she will investigate structure -guided immunogen design and innovative vaccine strategies aimed at enhancing subdominant antibody responses. Mouse model immunization studies, immune sera analyses, FACS for immune cells analyses, B cell repertoire analysis and immunohistology are key tasks along with cloning, expression and purification of proteins, cell culture, etc. + Highly-motivated candidates with a recent PhD or MD/PhD in biomedical sciences and significant experience in immunology, molecular biology and biochemistry are encouraged to apply. + Technical experience in immunology and methods to examine immune responses (measurement of antibodies, B and T cell responses and B cell repertoire analyses and mouse modeling/handling etc.) are essential. + Skills in molecular cloning, biochemistry and cell culturing techniques/protein expression are highly desirable. + Candidates should have a publication record in peer-reviewed journals. + We are seeking a candidate with excellent writing and communication skills, able to work independently but also effectively with other lab members. + Applicants should include a short statement of research goals, CV and three references with their application. **Pay Transparency Statement** The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications. For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA) $72,000 - $76,385 At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are committed to having faculty and staff who offer multifaceted experiences. Cancer knows no boundaries and when it comes to hiring the most dedicated and compassionate professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply. Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law. **EEOC Poster**
    $72k-76.4k yearly 25d ago
  • Postdoctoral Research Fellow - Fischer Lab

    Dana-Farber Cancer Institute 4.6company rating

    Boston, MA jobs

    The Fischer Lab at Dana-Farber Cancer Institute is a Structural and Chemical Biology lab that combines molecular biology, computational biology, structural biology and chemistry with various 'Omics' techniques such as proteomics to study the pathways and protein complexes involved in the regulation of protein abundance via the ubiquitin proteasome system that are often associated with human diseases, including cancer. The Fischer lab integrates structural biology, molecular biology and computational guided approaches to address fundamental questions about the mechanistic principles that govern signaling through the ubiquitin proteasome system. Our laboratory is based at Dana-Farber Cancer Institute in Longwood Center and is an affiliate of the BCMP department at Harvard Medical School. We are affiliated with state of the art facilities for structural biology (cryo-EM, X-ray crystallography, NMR), chemistry, biophysics, cellular imaging, etc. and the lab also has expertise and equipment for mass spectrometry including tims TOF pro and Orbitrap Eclipse tribrid mass spectrometers. Join our highly interactive team of scientists, postdocs, graduate students and technicians to work on understand signaling through the ubiquitin proteasome pathway and leverage these insights to test new avenues for therapeutic development. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world-renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. The Fischer Lab (************************ seeks a highly motivated individual to join the team as a POSTDOCTORAL RESEARCH FELLOW who will work on biochemistry and structural biology projects addressing fundamental questions in our understanding of the ubiquitin system. While we consider various backgrounds, a strong interest in understanding how molecular machines work and the desire to tackle a major problem of great significance are absolutely essential. + Recent Ph.D. or equivalent degree in structural biology (X-ray crystallography, electron microscopy), biochemistry, biophysics or molecular biology. + Proven ability to develop and execute on complex structural biology projects. + Ability to collect and analyze experimental data, prepare research publications and communicate results + Ability to work in a collaborative and team environment + Excellent oral and written capabilities **Expertise in two or more of the following areas:** + Expertise in recombinant protein expression and purification + Experience with insect and/or mammalian expression systems + Proficiency in data collection and structure determination for either X-ray or cryo-EM + Experience with protein biophysical techniques + In vitro biochemistry and enzyme kinetics + Quantitative and computational skills **Pay Transparency Statement** The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications. For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA) $72,000 - $76,385 At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are committed to having faculty and staff who offer multifaceted experiences. Cancer knows no boundaries and when it comes to hiring the most dedicated and compassionate professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply. Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law. **EEOC Poster**
    $72k-76.4k yearly 60d+ ago
  • Postdoctoral Research Fellow - Freeman Lab

    Dana-Farber Cancer Institute 4.6company rating

    Boston, MA jobs

    A postdoctoral position is available in the laboratory of Gordon Freeman in the Department of Medical Oncology at the Dana-Farber Cancer Institute, Harvard Medical School. The lab focuses on costimulatory and coinhibitory pathways, particularly the PD-L1/PD-1 and HHLA2/KIR3DL3 pathways Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. This position will involve examining the role of PD-1 and other coinhibitory pathways in immune responses and particularly on therapeutic synergies of coinhibitory blockade for anti-tumor immunity. A background in immunology and mouse tumor models is essential. Experience in working with T cells, antigen-presenting cells, cell culture, immunological techniques, multicolor flow cytometry, sc RNA analysis are highly desirable. + Candidates should have a Ph.D. and/or M.D. + The candidate must be a self-starter capable of generating new ideas with a strong work ethic and intensely curious with a love of discovery. + Please send 1) a cover letter briefly summarizing your research interests and career goals, CV, and contact information for three references to: gordon_************************ **Pay Transparency Statement** The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications. For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA) $72,000 - $76,385 At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are committed to having faculty and staff who offer multifaceted experiences. Cancer knows no boundaries and when it comes to hiring the most dedicated and compassionate professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply. Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law. **EEOC Poster**
    $72k-76.4k yearly Easy Apply 60d+ ago
  • Postdoctoral Research Fellow - Freed-Pastor Lab

    Dana-Farber Cancer Institute 4.6company rating

    Boston, MA jobs

    The Freed-Pastor Laboratory at Dana-Farber Cancer Institute and Harvard Medical School is seeking a highly-motivated, creative, and collaborative postdoctoral research fellow to join the team. The Freed-Pastor lab investigates how pancreatic cancer escapes immune eradication to guide novel therapies for pancreatic cancer patients. The lab employs cutting-edge technologies (immunopeptidomics, T cell engineering, single-cell transcriptomics, spatial transcriptomics, CRISPR technologies) paired with in vivo animal model systems and human patient-derived biospecimens (organoids and T cells). The candidate should have a strong background in immunology and/or tumor immunology. Experience with T cell engineering (CAR-T, TCR-T) and/or immunopeptidomics is preferred (but not required). Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. The candidate will lead independent research projects, report progress and track deliverables, work to develop innovative approaches to advance the field of tumor immunology and pancreatic cancer treatment, and help to train, supervise and mentor staff as needed. + Ph.D., M.D., M.D./Ph.D., or doctoral equivalent in a relevant field (immunology, cancer biology, or equivalent) + Demonstrated scientific contributions to the field + Proven ability to solve challenging technical problems + Clarity of thought in written and oral communication skills **Pay Transparency Statement** The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications. For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA) $72,000 - $76,385 At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are committed to having faculty and staff who offer multifaceted experiences. Cancer knows no boundaries and when it comes to hiring the most dedicated and compassionate professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply. Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law. **EEOC Poster**
    $72k-76.4k yearly 60d+ ago
  • Post-Doctoral Research Fellow

    Brigham and Women's Hospital 4.6company rating

    Boston, MA jobs

    Site: The Brigham and Women's Hospital, Inc. Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. Job Summary A postdoctoral research fellow position is available at Brigham and Women's Hospital/ Harvard Medical School, Boston. The laboratory's research is interested in understanding the role of non-coding RNAs (mi RNAs/lnc RNAs) and their signaling pathways/targets in a range of vascular disease states including atherosclerosis and ischemic injury in the heart and limb with a major focus in diabetes. The specific projects deal with understanding the mechanisms and functions of identified non-coding RNAs in cell types important to cardiovascular disease and diabetes such as endothelial cells, vascular smooth muscle cells, and leukocyte subsets. Studies will involve understanding specific aspects of non-coding RNAs and target gene function in vitro and in vivo using mouse knockout, knockdown, or overexpression studies, and translational assessment in human specimens. Qualifications Candidate must have a strong background in molecular and cellular biology, or vascular biology, outstanding written and verbal communication skills, be self-motivated, have demonstrated productivity, and ability to be independent while also working in a team environment. Experience in molecular biology and mice is strongly preferred. Candidates must be able to make a 2-year commitment. Degree Required: Ph.D. or M.D. Interested candidates are asked to send curriculum vitae and name/contact information of 3 references to: Mark Feinberg, MD, Professor of Medicine, Brigham and Women's Hospital and Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115; EMAIL to: ************************* Additional Job Details (if applicable) Remote Type Onsite Work Location 77 Avenue Louis Pasteur EEO Statement: The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at **************. Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership "looks like" by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
    $45k-57k yearly est. Auto-Apply 37d ago
  • Research Fellow, PGY 2 (Chekuri)

    Brigham and Women's Hospital 4.6company rating

    Boston, MA jobs

    Site: Massachusetts Eye and Ear Infirmary Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. Job Summary Summary Proposes and undertakes a mentored, innovative project or challenge to develop novel molecular therapies for inherited retinal degenerative diseases (IRD's). Involves in the study of host-AAV interactions, retinal tropism, and development of enabling gene therapy technologies, with a potential for translation of preclinical therapeutic gene transfer programs. Perform in vivo experiments involving the characterization of retinal phenotypic defects in mouse models of IRD's. Designs and performs in vitro and animal experiments, analyzes, and presents the outcome. Qualifications ESSENTIAL FUNCTIONS: * Read, analyze, and summarize published literature * Design and execute in vitro and in vivo. * Undertake relevant coursework if required by mentor. * Attend relevant meetings. * Meet regularly with the mentor to review project progress and milestones * Plan and deliver a seminar on the project * Take administrative (inventory, purchasing, etc. ) responsibilities in the lab when necessary * Write a final report or submit a manuscript to a peer-reviewed journal describing the project and results EDUCATION AND EXPERIENCE: Doctoral degree (MD or PhD) with more than 1 year of lab experience. WORKING CONDITIONS: Lab setting. PHYSICAL REQUIREMENTS: Possible lifting of 10 to 20 lbs., depending on nature of chosen project(s). HIPAA Privacy Training and Sanctions All employees who have access to health information whose confidentiality is protected by the HIPAA Privacy Rule are required by the Rule to receive training so that they have an understanding and knowledge of the Privacy Rule that corresponds to their job responsibilities and of the group health plan's policies and procedures that impact on their job duties. Training on the requirements of the HIPAA Privacy Rule and the plan's health information policies and procedures under the direction of the institution's privacy officer is a pre-requisite for this position. Employees who violate the requirements of the HIPAA Privacy Rule will be subject to discipline, up to and including termination. This description is intended to indicate essential tasks and levels of work difficulty that will be required of positions that will be given this title. It is not intended to limit or in any way modify the right of supervisors to assign, direct, or control the work of staff members under their supervision. The use of a particular expression or illustration describing duties shall not be held to exclude other duties not mentioned but that are of similar kind or level of difficulty. Additional Job Details (if applicable) Remote Type Onsite Work Location 20 Staniford Street Scheduled Weekly Hours 40 Employee Type Regular Work Shift Day (United States of America) EEO Statement: Massachusetts Eye and Ear Infirmary is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at **************. Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership "looks like" by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
    $45k-57k yearly est. Auto-Apply 35d ago
  • Clinical Post-Doctoral Fellow

    Brigham and Women's Hospital 4.6company rating

    Boston, MA jobs

    Site: Massachusetts General Physicians Organization, Inc. Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. Job Summary HOW TO APPLY: To apply, please submit your CV and a letter of interest to mgh_****************** The Massachusetts General Hospital (MGH) Center of Excellence (COE) for Psychosocial and Systemic Research, in partnership with the MGH Department of Psychiatry, Harvard Medical School (HMS), and the Massachusetts Department of Mental Health, is recruiting two full-time, one-year postdoctoral fellows. We seek to recruit trainees who have an interest in pursuing a clinical career in public or community mental health treatment settings, implementing evidence-based practices in these settings, and optimizing systems of care to promote health equity. Each one-year, full-time clinical post-doctoral psychology position provides focused training experiences in evidence-based psychosocial treatments and rehabilitation approaches for serious mental illness (SMI) and is designed to help trainees develop an understanding of, and facility with, assisting patients and families to navigate the public and community system of psychiatric care in Massachusetts. Inpatient and outpatient settings comprise the training experience and although there is a focus on SMI, trainees also have the opportunity to gain experience with a broad range of psychological presentations in an outpatient community behavioral health setting. Experiences are designed to provide trainees with an understanding of best practices in psychotherapy and psychiatric rehabilitation for individuals with SMI as well as underserved and vulnerable populations treated in public and community settings who may experience a range of adverse social determinants of health, including poverty, immigration challenges, homelessness, and trauma. Training experiences can be tailored to the interests of the trainee. While the fellowship has a primary clinical training focus, research opportunities are available through the COE. The selected candidate will join a vibrant clinical and research community at MGH, located in Boston's West End. He/She/They will be recommended for an academic appointment as a clinical fellow at HMS and will have access to MGH's employee benefits plan. Qualifications HOW TO APPLY: To apply, please submit your CV and a letter of interest to mgh_****************** Key responsibilities include: * Experience working as part of an interdisciplinary early intervention service for first episode psychosis; training opportunities with individuals with longer histories of SMI as well as those identified as being at clinical high-risk are also available (see ***************************************************** * Inpatient experience in a DMH-facility serving eligible individuals with SMI as well as a forensic population * Training experiences in providing outpatient care for a broad range of psychological disorders at one of the MGH Community Health Centers Qualifications: * PhD in clinical psychology, counseling psychology, or a related field * At least 3 years of clinical experience, inclusive of experience acquired during doctoral training Additional desirable experiences and skills: * Fluency in another language, preferably Spanish * Clinical training and experience working with child and adolescent populations * Clinical training and experience with evidence-based treatments for trauma and/or trauma-informed care * Clinical license eligibility upon completion of a one-year post-doctoral fellowship * Interest or experience in community-based participatory engagement/research or lived experience engagement/research As an equal opportunity and affirmative action employer, we recognizes the power of a diverse community and encourages applications from individuals with varied experiences, perspectives, and backgrounds. Additional Job Details (if applicable) Remote Type Hybrid Work Location 15 Parkman Street EEO Statement: Massachusetts General Physicians Organization, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at **************. Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership "looks like" by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
    $45k-57k yearly est. Auto-Apply 51d ago
  • Postdoc Research Fellow Psychiatry

    Brigham and Women's Hospital 4.6company rating

    Somerville, MA jobs

    Site: The Brigham and Women's Hospital, Inc. Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. Job Summary The Psychiatry Neuroimaging Laboratory at Brigham and Women's Hospital is seeking a full-time Postdoctoral Research Fellow to join our growing team. The fellow will work under the primary mentorship of Dr. Johanna Seitz-Holland, with additional guidance from Dr. Marek Kubicki. The fellow will be working on several funded projects examining psychosis across the lifespan using neuroimaging, clinical, and blood protein data. This is an exciting opportunity to contribute to impactful research while developing a strong foundation in translational psychiatry. We are a dynamic team committed to fostering a collaborative, supportive, and intellectually curious environment. Dr. Seitz-Holland takes mentoring seriously and is dedicated to creating a positive work atmosphere where team members can grow professionally and personally. We welcome applicants who are motivated, eager to learn, and excited to be part of a team working toward meaningful change in mental health research.The fellow will also have the opportunity to participate in the Stuart T. Hauser Research Training Program in Biological and Social Psychiatry (T32 position), which provides further structured training and career development support. Responsibilities include, but are not limited to: Assisting with quality control and curation of data collected as part of the psychosis projects. Processing imaging and blood data. Analyzing and modeling complex datasets, including neuroimaging, behavioral, and clinical data. Presenting at national and international meetings and building an active research/publication record. Assisting with grant writing. Supervising research assistants and undergraduate research trainees. Actively participating in the T32 training program. Qualifications Requirements: Ph.D. in Neuroscience, Clinical Neuroscience, Cognitive Science, Psychology, Engineering, Computer Science, or a related field. Background in data processing, statistics, biostatistics, or data modeling. Experience in processing and analysis of neuroimaging data is desired but not required. Strong verbal and written communication skills. Ability to work independently and collaboratively within a team. Demonstrated first-author publication record or pre-print experience. Most importantly, a genuine interest in psychiatry, motivation to work in a team, and excitement for research. Prior work authorization required (no visa sponsorship available). We're excited to learn more about you! To apply for this position, please email your resume directly to Johanna Seitz at **********************. Please do not apply through this link. Additional Job Details (if applicable) Remote Type Hybrid Work Location 399 Revolution Drive EEO Statement: The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at **************. Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership "looks like" by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
    $45k-57k yearly est. Auto-Apply 29d ago
  • Bioinformatician II

    Dana-Farber Cancer Institute 4.6company rating

    Boston, MA jobs

    The Center for Cancer Genomics (CCG) at Dana-Farber Cancer Institute facilitates genomic discoveries in cancer using novel technology platforms to assist researchers in both genome-wide and gene-focused efforts. Technologies are selected and developed with a view to research-oriented ventures, as well as translational medicine and clinical relevance. Our clinical and research environments currently use state-of-the-art massively parallel sequencing assays of DNA and RNA from patient tumor samples. Data from these environments are used to advance research on both adult and pediatric cancers, improve our understanding of cancer biology, and advance the field of precision cancer medicine. This opportunity offers the chance to work at the forefront of translational cancer technologies and applications, in an informatics group that enables analyses in both arenas. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. Responsibilities The Bioinformatician II will report to CCG's Lead Informaticist and have the main responsibility of independently performing data analysis on a wide array of cancer multiomics projects (sc/sn RNAseq, sc ATACseq, Crispr screens, SNV/CNV, longread Oxford Nanopore Direct RNA sequencing, etc.) in consultation and collaboration with internal Dana-Farber research collaborators and external research partners. Some limited orchestration of automated pipelines may be required as necessary. The Bioinformatician II will have no direct reports. Dana-Farber has a wealth of local, on-premises, and cloud-based computing resources available to extensively explore the large body of data generated annually by Dana-Farber researchers and collaborators. Given these resources, the development of novel computational methods is strongly encouraged. Qualifications MINIMUM JOB QUALIFICATIONS: Minimum Education: Bachelor's degree required in a STEM field. Master's degree or PhD strongly preferred in bioinformatics, medical informatics, computational biology, statistics, computer science/engineering, or a related quantitative field. Minimum Education: 3 Years of experience required; Master's degree with 1 year experience required; PhD with 0 years. * Experience with bioinformatics tools and databases for sequence alignment/analysis; germline and somatic variant calling; bulk and single-cell/nuclei RNAseq; long read sequencing (Oxford Nanopore). * Proficiency in programming languages commonly used in bioinformatics and data analysis, such as Python, R, and Perl. Experience with workflow languages such as WDL or Nextflow is a plus. * Excellent communication skills and ability to work collaboratively in multi-disciplinary team. Pay Transparency Statement The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications. For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA) $83,800 - $90,800 At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply. Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law. EEOC Poster
    $83.8k-90.8k yearly Auto-Apply 33d ago
  • Bioinformatician II

    Dana-Farber Cancer Institute 4.6company rating

    Boston, MA jobs

    The **Center for Cancer Genomics** **(CCG)** at Dana-Farber Cancer Institute facilitates genomic discoveries in cancer using novel technology platforms to assist researchers in both genome-wide and gene-focused efforts. Technologies are selected and developed with a view to research-oriented ventures, as well as translational medicine and clinical relevance. Our clinical and research environments currently use state-of-the-art massively parallel sequencing assays of DNA and RNA from patient tumor samples. Data from these environments are used to advance research on both adult and pediatric cancers, improve our understanding of cancer biology, and advance the field of precision cancer medicine. This opportunity offers the chance to work at the forefront of translational cancer technologies and applications, in an informatics group that enables analyses in both arenas. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. The **Bioinformatician II** will report to CCG's Lead Informaticist and have the main responsibility of independently performing data analysis on a wide array of cancer multiomics projects ( _sc/sn RNAseq, sc ATACseq, Crispr screens, SNV/CNV, longread Oxford Nanopore Direct RNA sequencing,_ etc.) in consultation and collaboration with internal Dana-Farber research collaborators and external research partners. Some limited orchestration of automated pipelines may be required as necessary. The Bioinformatician II will have no direct reports. Dana-Farber has a wealth of local, on-premises, and cloud-based computing resources available to extensively explore the large body of data generated annually by Dana-Farber researchers and collaborators. Given these resources, the development of novel computational methods is strongly encouraged. **MINIMUM JOB QUALIFICATIONS:** Minimum Education: Bachelor's degree required in a STEM field. Master's degree or PhD strongly preferred in bioinformatics, medical informatics, computational biology, statistics, computer science/engineering, or a related quantitative field. Minimum Education: 3 Years of experience required; Master's degree with 1 year experience required; PhD with 0 years. + Experience with bioinformatics tools and databases for sequence alignment/analysis; germline and somatic variant calling; bulk and single-cell/nuclei RNAseq; long read sequencing (Oxford Nanopore). + Proficiency in programming languages commonly used in bioinformatics and data analysis, such as Python, R, and Perl. Experience with workflow languages such as WDL or Nextflow is a plus. + Excellent communication skills and ability to work collaboratively in multi-disciplinary team. **Pay Transparency Statement** The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications. For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA) $83,800 - $90,800 At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply. Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law. **EEOC Poster**
    $83.8k-90.8k yearly 32d ago
  • Research Scientist

    Brigham and Women's Hospital 4.6company rating

    Boston, MA jobs

    Site: The Brigham and Women's Hospital, Inc. Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. Job Summary Summary In consultation with their Principal Investigator (PI), undertake and execute a program of scientific study culminating in publication. Drives research projects scientifically and determines the course of research as evidenced by leadership, obtaining funding, writing, or other recognition. May not necessarily receive independent resources; however, their contribution is essential to the conceptual/scientific success of the project. They assist their PI in the training and supervision of other laboratory personnel and in a wide variety of administrative tasks, as necessary. Does this position require Patient Care? No Essential Functions * Makes proficient intellectual contributions to scientific strategies of the group/lab and plays a leadership role by acting as subject matter authority in the field. * Contributes to the design and execution of experiments and/or research projects. * Exercises judgment in selecting methods and technologies to obtain results. * May collaborate with external researchers and/or receive external project funding support. * Presents results and prepares publications. * May assist PI in the training and supervision of other staff. Qualifications This position in the BWH Center for Cellular Profiling offers the opportunity to join a group studying single-cell and Spatial organization in disease pathology. Our Center performs a combination of high-dimensional analyses, including single-cell RNA sequencing, spatial transcriptomics, and high-dimensional flow cytometry. Under general supervision by Drs. Brenner and Wei, and in accordance with established hospital policies and procedures, the self-motivated individual will perform activities related to the single-cell genomics and or flow cytometry cell sorting, including NGS library generation, 10X Genomics workflow (Chromium, Visium, and Xenium), and or familiarize with BD or Sony cell sorters and analyzers. Responsibilities includes the implementation and execution of single-cell and novel spatial transcriptomic techniques. In addition, the candidate will supervise trainees and technicians to perform NGS and 10X Genomics pipelines. The candidate will also conduct consultation with investigators and core users, perform troubleshooting, and work with administrative directors to support budget development and planning. 1. Designs and performs high-level, complex experiments independently. 2. Perform Single-cell Transcriptomics Experiments. a. Cell capture, NGS library generation, b. Plan library sequencing strategies. c. Review sequencing data d. troubleshoot techniques 3. Perform High-Parameters Flow Cytometry Experiments a. Perform cell sorting b. Maintenance of the cell sorters and analyzers c. Identify and resolve technical issues with flow cytometry instruments, maintaining equipment, and ensuring quality control. 4.Supervise research assistant trainees. 5.Provide consultation with new investigators and researchers 6.Maintain supplies inventory in accordance with laboratory and department procedures. 7.Assist in the orientation and training of new students, technicians, and fellows 8.Maintain established department policies, procedures and objectives, including the areas of quality assurance, safety, environmental and infection control. 9. Perform other duties as directed. Education Doctorate Related Field of Study required Can this role accept experience in lieu of a degree? No Licenses and Credentials Experience Previous Research experience (inclusive of graduate and postdoctoral experience) 5-7 years required Knowledge, Skills and Abilities * Excellent research skills. * Demonstrated evidence of specific scientific competence in field. * Demonstrated broad knowledge of field. * Evidence of potential for scientific creativity and original though. * Able to exercise independent judgment and leadership. * Ability to contribute to publications. Additional Job Details (if applicable) Remote Type Onsite Work Location 60 Fenwood Road Scheduled Weekly Hours 40 Employee Type Regular Work Shift Day (United States of America) EEO Statement: The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at **************. Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership "looks like" by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
    $50k-73k yearly est. Auto-Apply 3d ago
  • Research Scientist

    Brigham and Women's Hospital 4.6company rating

    Boston, MA jobs

    Site: The Brigham and Women's Hospital, Inc. Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. Job Summary A research laboratory within the Brigham and Women's Hospital Division of Cardiovascular Medicine is seeking a highly motivated Research Scientist to join a growing, interdisciplinary team. The lab uses both in vitro (human ESC/iPSC) and in vivo (zebrafish) systems to model cardiovascular disorders and integrates transcriptional, (epi)genetic, metabolic, and phenotypic profiling at whole-organism, tissue, and single-cell levels. Our goal is to define the earliest molecular events driving disease onset, characterize their dynamic changes over time, and identify novel biomarkers and therapeutic targets. The Research Scientist will lead and directly perform automated, high-throughput microscopy screens to identify small-molecule compounds with improved efficacy over current clinical therapies. The role will involve hands-on execution of complex imaging workflows and the application of machine-learning approaches to large-scale imaging and phenotyping datasets. In addition, the Research Scientist will serve as the primary scientific point person for multiple industry collaborations, coordinating experimental design, execution, data generation, and communication between external partners and the lab. The Research Scientist will independently drive scientific projects, determine research direction in collaboration with the PI, and serve as an internal expert in automated imaging and computational analysis. The successful candidate will generate high-quality data, contribute substantially to scientific publications, mentor junior staff, engage with collaborators, and may participate in the development of external funding applications. Qualifications GENERAL SUMMARY/ OVERVIEW STATEMENT: A research laboratory within the Brigham and Women's Hospital Division of Cardiovascular Medicine is seeking a highly motivated Research Scientist to join a growing, interdisciplinary team. The lab uses both in vitro (human ESC/iPSC) and in vivo (zebrafish) systems to model cardiovascular disorders and integrates transcriptional, (epi)genetic, metabolic, and phenotypic profiling at whole-organism, tissue, and single-cell levels. Our goal is to define the earliest molecular events driving disease onset, characterize their dynamic changes over time, and identify novel biomarkers and therapeutic targets. The Research Scientist will lead and directly perform automated, high-throughput microscopy screens to identify small-molecule compounds with improved efficacy over current clinical therapies. The role will involve hands-on execution of complex imaging workflows and the application of machine-learning approaches to large-scale imaging and phenotyping datasets. In addition, the Research Scientist will serve as the primary scientific point person for multiple industry collaborations, coordinating experimental design, execution, data generation, and communication between external partners and the lab. The Research Scientist will independently drive scientific projects, determine research direction in collaboration with the PI, and serve as an internal expert in automated imaging and computational analysis. The successful candidate will generate high-quality data, contribute substantially to scientific publications, mentor junior staff, engage with collaborators, and may participate in the development of external funding applications. PRINCIPAL DUTIES AND RESPONSIBILITIES: * Provide overall scientific leadership and project management for assigned research initiatives, including direct execution of experimental work. * Design, optimize, and perform high-throughput automated imaging and screening assays, including day-to-day hands-on operation of imaging platforms and related instruments. * Conduct complex and innovative experiments using in vitro (human ESC/iPSC) and in vivo (zebrafish) models; troubleshoot technical challenges and refine protocols as needed. * Serve as a subject-matter expert while actively generating data, maintaining experimental quality, and ensuring reproducibility. * Exercise professional judgment in selecting experimental strategies, technologies, and analytical methods to obtain high-quality results. * Make project-level decisions to address and resolve critical scientific or technical challenges. * Regularly present results to the PI and contribute to preparation of manuscripts, reports, and presentations. * Collaborate with external partners as the scientific point person for industry-funded projects, ensuring high-quality and timely experimental deliverables. * Maintain an active publication record as senior author or substantial contributor, demonstrating scientific independence. * Participate in relevant scientific societies, committees, and professional activities. * Train and mentor junior research staff in laboratory techniques, data analysis approaches, and best practices in research execution. * Contribute to long-term strategic planning for the laboratory's research direction, technologies, and collaborative projects. QUALIFICATIONS: * PhD in molecular biology, molecular genetics, or a closely related field strongly preferred; an MS with substantial additional experience may be considered. * Prior experience with zebrafish research is required. * Minimum of 5 years of relevant research experience, including demonstrated independence. SKILLS/ ABILITIES/ COMPETENCIES REQUIRED: * Strong expertise and technical proficiency in molecular biology, cell biology, and genetics. * Demonstrated experience using model organisms (preferably zebrafish) for high-throughput drug or modifier screens. * Proven ability to design, execute, and troubleshoot complex research projects. * Ability to define project objectives, develop experimental approaches, and interpret results. * Strong scientific writing skills with a record of impactful contributions to peer-reviewed publications. * Excellent organizational, communication, and leadership skills. * Ability to work both independently and collaboratively within a multidisciplinary research team. WORKING CONDITIONS: Wet-lab/office setting. SUPERVISORY RESPONSIBILITY: May be responsible for managing junior staff or research assistants. Additional Job Details (if applicable) Remote Type Onsite Work Location 221 Longwood Avenue Scheduled Weekly Hours 40 Employee Type Regular Work Shift Day (United States of America) EEO Statement: The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at **************. Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership "looks like" by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
    $50k-73k yearly est. Auto-Apply 7d ago
  • Associate Computational Biologist

    Dana-Farber Cancer Institute 4.6company rating

    Boston, MA jobs

    The laboratory of Zuzana Tothova, MD, PhD is a multi-disciplinary team of physician scientists, scientists and computational biologists at the Dana-Farber Cancer Institute and the Broad Institute. Our laboratory uses genomics and a range of molecular and cellular biological techniques to elucidate the molecular basis of cancer and hematologic disorders and to develop novel therapeutics. Our specific focus is to understand the role of chromatin modifiers and epigenetic factors and find novel therapeutic opportunities in myeloid malignancies, including myelodysplastic syndromes and acute myeloid leukemia. JOB TITLE: Associate computational biologist FLSA: Full-time, on-site REPORTS TO: Zuzana Tothova, M.D., Ph.D. DEPT: Medicine Oncology/ Heme Neoplasia **General Summary** A full-time associate computational biologist position is available in the laboratory of Zuzana Tothova, M.D., Ph.D. at Dana-Farber Cancer Institute. We are seeking enthusiastic, self-motivated individuals who thrive in a fast-paced, challenging research environment, and can interact well with others as part of a cohesive team. If you have a desire to make a significant impact in healthcare and have the fortitude to work hard, you will succeed within this team. This is an ideal entry-level or mid-level position into the world of cutting-edge laboratory research. A growth mindset and a willingness to take on challenging learning opportunities will be sought out traits. Ideal candidates will possess strong interpersonal skills along with a desire to help others to succeed. Previous team members have gone on to successful academic and career opportunities; graduate/medical school and industry. The candidate will be involved in a series of research activities, including computational analysis of large-scale data sets generated in in vitro and in vivo human disease relevant models and use of next generation sequencing with a special emphasis on understanding the biology of human myeloid malignancies. The Associate Computational Biologist is training to become a Computational Biologist. They are responsible for routine data analysis or processing of biological data, with a focus on high-throughput technologies and genomic databases, under the supervision of mentor. The Computational Biologist is a quantitative scientist who collaborates with scientific investigators and with other research staff in the analysis of high-throughput data, and dissemination of scientific results. The Computational Biologist may work on many types of projects and areas of research including cancer genomics, functional genomics, immuno-oncology, molecular imaging, data management and integration, and querying biological databases. **We are looking for candidates with at least 2 years of availability.** Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. **PRIMARY DUTIES AND RESPONSIBILITIES:** 1. Data Processing Builds data processing pipelines to convert raw data into formats compatible with conventional statistical analysis and visualization under supervision of mentor. 2. Data Analysis: Follows a detailed manual to perform routine. 3. Data and Software Management: Monitors, downloads, organizes, and manages data from public data repositories or generated by collaborates. 4. Manuscript Preparation: Helps prepare tables and figures. 5. Research Portfolio Management: Trains to develops timelines and components for multiple routine projects; masters multi-tasking so that complex projects involving many interdisciplinary individuals move forward smoothly. 6. Works closely with postdoctoral fellows and graduate students in the lab and computational biology collaborators at the Dana-Farber Cancer Institute and the Broad Institute to analyze biological data sets, including but not limited to DNA and RNA sequencing, gene expression and transcriptome analysis, chromatin landscape profiling, and analysis of microscopy/imaging data. 7. Modifies and maintains existing data-processing pipelines in the lab, and develops new pipelines and tools to analyze novel forms of data, including data cleaning, normalization, and visualization. 8. Integrates multiple data sets to answer targeted scientific questions. 9. Documents and compiles findings in oral and written reports. 10. Attends team meetings to share results, plan projects and experiments. 11. Maintains and improves technical knowledge base. 12. Other related tasks as required. **KNOWLEDGE, SKILLS, AND ABILITIES REQUIRED:** + Computational Skills: Knowledge of UNIX/Linux. Proficiency with scripting in Python and statistical programming using R. + Data analysis Skills: Familiarity with principles of experimental design and the modern data analysis paradigms is required. + Collaboration: Able to discuss and present results, share ideas accurately and communicate them effectively, both in writing and verbally with supervisory oversight. **MINIMUM JOB QUALIFICATIONS:** Minimum Education: Bachelor's degree in a computer science or related-STEM field required. Minimum Experience: No prior experience required. **KNOWLEDGE, SKILLS, AND ABILITIES REQUIRED:** + Computational Skills: Knowledge of UNIX/Linux. Proficiency with scripting in Python and statistical programming using R. + Data analysis Skills: Familiarity with principles of experimental design and the modern data analysis paradigms is required. + Collaboration: Able to discuss and present results, share ideas accurately and communicate them effectively, both in writing and verbally with supervisory oversight. + Strong interpersonal skills - ability to effectively interact with all levels of staff and external contacts. + Excellent analytical, organizational and time management skills. + Familiarity with bioinformatics data types and software preferred + Familiarity with GitHub and HPC preferred + Passion for science and strong motivation required. + Must be a strong team player. + Strong interpersonal, communication and organizational skills, including the ability to handle a variety of tasks in a fast-paced environment, positive attitude and attention to detail, as well as ability to think on one's feet are required. + Must possess a high level of initiative, curiosity and dedication, proactivity in identifying problems and solutions to address them. + Familiarity with bioinformatics data types (e.g. FastQ, BAM, BigWig) and software (e.g. DeepTools, MACS, HOMER) preferred. + Familiarity working with Git repositories preferred. + Familiarity with computational methods for single-cell sequencing data preferred. **Pay Transparency Statement** The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications. For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA) $60,000 - $67,466 At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply. Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law. **EEOC Poster**
    $60k-67.5k yearly 51d ago
  • Associate Computational Biologist

    Dana-Farber Cancer Institute 4.6company rating

    Boston, MA jobs

    A computationally-oriented team led by Rameen Beroukhim and Simona Dalin at the Dana-Farber Cancer Institute and Broad Institute seeks an associate computational biologist to join in efforts to develop and apply cutting-edge genomic algorithms and analyses to characterize genomic rearrangements in cancers and normal tissues, and better understand how errors in double strand break (DSB) repair result in these rearrangements. This individual will contribute to a lively team and wider community of laboratory scientists, computational biologists, cancer geneticists, and software engineers dedicated to discovering and understanding the alterations in the cancer genome and discovering cancer vulnerabilities that could lead to new therapeutics. We are looking for a person who wants to lead their projects, think independently and make original intellectual contributions. We welcome all levels of input from our ACBs, including input on the conduct of analyses but also on new analyses to conduct and new questions to ask. ACBs in our laboratory regularly present their own work and contribute to the writing of papers and grant applications. We view an ACB as a mentored training position, with a primary goal being their professional development. Our prior ACBs have successfully pursued a variety of subsequent career directions including obtaining MDs, PhDs, and MD-PhDs on the paths to careers in both academia and industry. The ideal candidate will have extensive programming ability and a strong background in mathematics and statistics with a deep interest and background in biology. The candidate is required to have a B.S./B.A. or equivalent, ideally in the life sciences, physical sciences, or computational sciences; prior research in one of these areas (for example, a summer research program or several hours a week in a lab as an undergraduate); a strong background in programming, preferably in R and BASH; knowledge of statistical methods either through coursework or research; and excellent written & verbal communication skills. They must be a self-starter with excellent problem-solving, organizational and people skills and be able to collaborate closely with other members of a research team. We prefer the candidate to have exposure to an analytic field such as bioinformatics, computational biology, machine learning, or statistics and experience working in cloud computing and UNIX environments. A minimum 2 year commitment is required. Ideally we are looking for someone to join our lab before March 2026 but we are also considering applicants who will complete their current degree program in Spring 2026. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. + Data Processing Builds data processing pipelines to convert raw data into formats compatible with conventional statistical analysis and visualization under supervision of mentor. + Data Analysis: Follows a detailed manual to perform routine. + Data and Software Management: Monitors, downloads, organizes, and manages data from public data repositories or generated by collaborates. + Manuscript Preparation: Helps prepare tables and figures. + Research Portfolio Management: Trains to develops timelines and components for multiple routine projects; masters multi-tasking so that complex projects involving many interdisciplinary individuals move forward smoothly. **MINIMUM JOB QUALIFICATIONS:** Minimum Education: Bachelor's degree required in a STEM field required. Minimum Experience: No prior experience required **.** **KNOWLEDGE, SKILLS, AND ABILITIES REQUIRED:** + Computational Skills: Knowledge of UNIX/Linux. Familiarity with scripting in Python and statistical programming using R. + Data analysis Skills: Familiarity with principles of experimental design and the modern data analysis paradigms is required. + Collaboration: Able to discuss and present results, share ideas accurately and communicate them effectively, both in writing and verbally with supervisory oversight. + Strong interpersonal skills - ability to effectively interact with all levels of staff and external contacts. + Excellent analytical, organizational and time management skills. **Pay Transparency Statement** The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications. For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA) $60,000 - $67,466 At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply. Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law. **EEOC Poster**
    $60k-67.5k yearly 7d ago
  • Associate Computational Biologist

    Dana-Farber Cancer Institute 4.6company rating

    Boston, MA jobs

    A computationally-oriented team led by Rameen Beroukhim and Simona Dalin at the Dana-Farber Cancer Institute and Broad Institute seeks an associate computational biologist to join in efforts to develop and apply cutting-edge genomic algorithms and analyses to characterize genomic rearrangements in cancers and normal tissues, and better understand how errors in double strand break (DSB) repair result in these rearrangements. This individual will contribute to a lively team and wider community of laboratory scientists, computational biologists, cancer geneticists, and software engineers dedicated to discovering and understanding the alterations in the cancer genome and discovering cancer vulnerabilities that could lead to new therapeutics. We are looking for a person who wants to lead their projects, think independently and make original intellectual contributions. We welcome all levels of input from our ACBs, including input on the conduct of analyses but also on new analyses to conduct and new questions to ask. ACBs in our laboratory regularly present their own work and contribute to the writing of papers and grant applications. We view an ACB as a mentored training position, with a primary goal being their professional development. Our prior ACBs have successfully pursued a variety of subsequent career directions including obtaining MDs, PhDs, and MD-PhDs on the paths to careers in both academia and industry. The ideal candidate will have extensive programming ability and a strong background in mathematics and statistics with a deep interest and background in biology. The candidate is required to have a B.S./B.A. or equivalent, ideally in the life sciences, physical sciences, or computational sciences; prior research in one of these areas (for example, a summer research program or several hours a week in a lab as an undergraduate); a strong background in programming, preferably in R and BASH; knowledge of statistical methods either through coursework or research; and excellent written & verbal communication skills. They must be a self-starter with excellent problem-solving, organizational and people skills and be able to collaborate closely with other members of a research team. We prefer the candidate to have exposure to an analytic field such as bioinformatics, computational biology, machine learning, or statistics and experience working in cloud computing and UNIX environments. A minimum 2 year commitment is required. Ideally we are looking for someone to join our lab before March 2026 but we are also considering applicants who will complete their current degree program in Spring 2026. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. Responsibilities * Data Processing Builds data processing pipelines to convert raw data into formats compatible with conventional statistical analysis and visualization under supervision of mentor. * Data Analysis: Follows a detailed manual to perform routine. * Data and Software Management: Monitors, downloads, organizes, and manages data from public data repositories or generated by collaborates. * Manuscript Preparation: Helps prepare tables and figures. * Research Portfolio Management: Trains to develops timelines and components for multiple routine projects; masters multi-tasking so that complex projects involving many interdisciplinary individuals move forward smoothly. Qualifications MINIMUM JOB QUALIFICATIONS: Minimum Education: Bachelor's degree required in a STEM field required. Minimum Experience: No prior experience required. KNOWLEDGE, SKILLS, AND ABILITIES REQUIRED: * Computational Skills: Knowledge of UNIX/Linux. Familiarity with scripting in Python and statistical programming using R. * Data analysis Skills: Familiarity with principles of experimental design and the modern data analysis paradigms is required. * Collaboration: Able to discuss and present results, share ideas accurately and communicate them effectively, both in writing and verbally with supervisory oversight. * Strong interpersonal skills - ability to effectively interact with all levels of staff and external contacts. * Excellent analytical, organizational and time management skills. Pay Transparency Statement The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications. For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA) $60,000 - $67,466 At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply. Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law. EEOC Poster
    $60k-67.5k yearly Auto-Apply 7d ago
  • Associate Computational Biologist

    Dana-Farber Cancer Institute 4.6company rating

    Boston, MA jobs

    The laboratory of Zuzana Tothova, MD, PhD is a multi-disciplinary team of physician scientists, scientists and computational biologists at the Dana-Farber Cancer Institute and the Broad Institute. Our laboratory uses genomics and a range of molecular and cellular biological techniques to elucidate the molecular basis of cancer and hematologic disorders and to develop novel therapeutics. Our specific focus is to understand the role of chromatin modifiers and epigenetic factors and find novel therapeutic opportunities in myeloid malignancies, including myelodysplastic syndromes and acute myeloid leukemia. JOB TITLE: Associate computational biologist FLSA: Full-time, on-site REPORTS TO: Zuzana Tothova, M.D., Ph.D.DEPT: Medicine Oncology/ Heme Neoplasia General Summary A full-time associate computational biologist position is available in the laboratory of Zuzana Tothova, M.D., Ph.D. at Dana-Farber Cancer Institute. We are seeking enthusiastic, self-motivated individuals who thrive in a fast-paced, challenging research environment, and can interact well with others as part of a cohesive team. If you have a desire to make a significant impact in healthcare and have the fortitude to work hard, you will succeed within this team. This is an ideal entry-level or mid-level position into the world of cutting-edge laboratory research. A growth mindset and a willingness to take on challenging learning opportunities will be sought out traits. Ideal candidates will possess strong interpersonal skills along with a desire to help others to succeed. Previous team members have gone on to successful academic and career opportunities; graduate/medical school and industry. The candidate will be involved in a series of research activities, including computational analysis of large-scale data sets generated in in vitro and in vivo human disease relevant models and use of next generation sequencing with a special emphasis on understanding the biology of human myeloid malignancies. The Associate Computational Biologist is training to become a Computational Biologist. They are responsible for routine data analysis or processing of biological data, with a focus on high-throughput technologies and genomic databases, under the supervision of mentor. The Computational Biologist is a quantitative scientist who collaborates with scientific investigators and with other research staff in the analysis of high-throughput data, and dissemination of scientific results. The Computational Biologist may work on many types of projects and areas of research including cancer genomics, functional genomics, immuno-oncology, molecular imaging, data management and integration, and querying biological databases. We are looking for candidates with at least 2 years of availability. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. Responsibilities PRIMARY DUTIES AND RESPONSIBILITIES: Data Processing Builds data processing pipelines to convert raw data into formats compatible with conventional statistical analysis and visualization under supervision of mentor. Data Analysis: Follows a detailed manual to perform routine. Data and Software Management: Monitors, downloads, organizes, and manages data from public data repositories or generated by collaborates. Manuscript Preparation: Helps prepare tables and figures. Research Portfolio Management: Trains to develops timelines and components for multiple routine projects; masters multi-tasking so that complex projects involving many interdisciplinary individuals move forward smoothly. Works closely with postdoctoral fellows and graduate students in the lab and computational biology collaborators at the Dana-Farber Cancer Institute and the Broad Institute to analyze biological data sets, including but not limited to DNA and RNA sequencing, gene expression and transcriptome analysis, chromatin landscape profiling, and analysis of microscopy/imaging data. Modifies and maintains existing data-processing pipelines in the lab, and develops new pipelines and tools to analyze novel forms of data, including data cleaning, normalization, and visualization. Integrates multiple data sets to answer targeted scientific questions. Documents and compiles findings in oral and written reports. Attends team meetings to share results, plan projects and experiments. Maintains and improves technical knowledge base. Other related tasks as required. KNOWLEDGE, SKILLS, AND ABILITIES REQUIRED: * Computational Skills: Knowledge of UNIX/Linux. Proficiency with scripting in Python and statistical programming using R. * Data analysis Skills: Familiarity with principles of experimental design and the modern data analysis paradigms is required. * Collaboration: Able to discuss and present results, share ideas accurately and communicate them effectively, both in writing and verbally with supervisory oversight. Qualifications MINIMUM JOB QUALIFICATIONS: Minimum Education: Bachelor's degree in a computer science or related-STEM field required. Minimum Experience: No prior experience required. KNOWLEDGE, SKILLS, AND ABILITIES REQUIRED: * Computational Skills: Knowledge of UNIX/Linux. Proficiency with scripting in Python and statistical programming using R. * Data analysis Skills: Familiarity with principles of experimental design and the modern data analysis paradigms is required. * Collaboration: Able to discuss and present results, share ideas accurately and communicate them effectively, both in writing and verbally with supervisory oversight. * Strong interpersonal skills - ability to effectively interact with all levels of staff and external contacts. * Excellent analytical, organizational and time management skills. * Familiarity with bioinformatics data types and software preferred * Familiarity with GitHub and HPC preferred * Passion for science and strong motivation required. * Must be a strong team player. * Strong interpersonal, communication and organizational skills, including the ability to handle a variety of tasks in a fast-paced environment, positive attitude and attention to detail, as well as ability to think on one's feet are required. * Must possess a high level of initiative, curiosity and dedication, proactivity in identifying problems and solutions to address them. * Familiarity with bioinformatics data types (e.g. FastQ, BAM, BigWig) and software (e.g. DeepTools, MACS, HOMER) preferred. * Familiarity working with Git repositories preferred. * Familiarity with computational methods for single-cell sequencing data preferred. Pay Transparency Statement The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications. For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA) $60,000 - $67,466 At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply. Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law. EEOC Poster
    $60k-67.5k yearly Auto-Apply 51d ago
  • Research Technologist - Ordovas-Montanes Lab

    Children's Hospital Boston 4.6company rating

    Boston, MA jobs

    This is an opportunity to join Ordovas-Montanes Lab, which specializes in understanding how inflammation drives memory formation in barrier tissues with the goal of developing new therapeutic avenues for human disease. This candidate will contribute to a collaborative project focused on mucosal immunity to respiratory infection and vaccination. The candidate will work under the direct supervision of Dr. Jose Ordovas-Montanes and be closely integrated within a community of senior scientists, graduate students, and postdoctoral fellows. This position requires substantial technical expertise, the ability to troubleshoot specialized assays, and the capacity to support and train junior lab members as needed. This role offers the opportunity to develop a wide range of experimental and computational skills while working in an interdisciplinary environment with access to resources across Boston Children's Hospital and Harvard Medical School. The ideal candidate is motivated to understand the biological principles underlying infection-induced inflammatory diseases and may be interested in pursuing future postgraduate education. Key Responsibilities: * Independently perform complex experimental workflows, help optimize protocols, and generate high-quality data for single-cell genomics and airway epithelial biology studies. * Troubleshoot specialized assays. * Support and train junior lab members as needed. * Performs routine and highly specialized lab experiments using sophisticated and intricate research equipment and techniques. Performs and devises specialized experiments and research procedures, troubleshooting problems with own and other researchers' results. * Assists other lab personnel with the use of specialized equipment and techniques within the lab. Minimum Qualifications Education: * Bachelor's degree in biology, immunology, genomics, chemistry, or a related field is required. Master's degree preferred but not required. Experience: * Bachelor's and 4 years of relevant experience OR a Master's of Science and 2 years of relevant experience. * Demonstrated experience performing mammalian cell culture, ideally primary airway epithelial culture or similar complex systems. * Proficiency in molecular biology techniques. * Proven ability to independently execute and troubleshoot complex laboratory workflows. * Experience with single-cell RNA-sequencing methods and data analysis in R and/or python is preferred but not required. The posted pay range is Boston Children's reasonable and good-faith expectation for this pay at the time of posting. Any base pay offer provided depends on skills, experience, education, certifications, and a variety of other job-related factors. Base pay is one part of a comprehensive benefits package that includes flexible schedules, affordable health, vision and dental insurance, child care and student loan subsidies, generous levels of time off, 403(b) Retirement Savings plan, Pension, Tuition and certain License and Certification Reimbursement, cell phone plan discounts and discounted rates on T-passes. Experience the benefits of passion and teamwork.
    $44k-55k yearly est. 3d ago

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