Doctoral Fellow jobs at Memorial Sloan Kettering Cancer Center - 296 jobs
Postdoctoral Fellow - AI & Computational Hematology
Memorial Sloan Kettering Cancer Center 4.1
Doctoral fellow job at Memorial Sloan Kettering Cancer Center
About Us:
The people of Memorial Sloan Kettering Cancer Center (MSK) are united by a singular mission: ending cancer for life. Our specialized care teams provide personalized, compassionate, expert care to patients of all ages. Informed by basic research done at our Sloan Kettering Institute, scientists across MSK collaborate to conduct innovative translational and clinical research that is driving a revolution in our understanding of cancer as a disease and improving the ability to prevent, diagnose, and treat it. MSK is dedicated to training the next generation of scientists and clinicians, who go on to pursue our mission at MSK and around the globe.
The HemeAI Lab at Memorial Sloan Kettering Cancer Center (MSKCC) is a clinical translational research laboratory focused on transforming cancer diagnosis, risk stratification, and disease monitoring through artificial intelligence. Our mission is to improve patient outcomes in leukemias and other hematologic diseases by developing clinically deployable, AI-powered tools that not only benefit MSKCC patients but also have strong potential for global clinical adoption and commercialization.
MSKCC is a world-leading cancer center with unparalleled clinical data, infrastructure, and multidisciplinary expertise, providing an exceptional environment for high-impact translational research.
Position Overview
We are seeking highly motivated postdoctoral fellows to join our interdisciplinary team led by Gregory Goldgof, MD, PhD, MS, Director of Artificial Intelligence for the Hematopathology Service. This is a paid postdoctoral position offering substantial independence, access to large-scale real-world clinical datasets, and close integration with clinical practice.
Postdoctoral fellows will play a central role in developing and validating AI systems for medical image analysis, LLM-based tooling, and multimodal clinical data integration, with opportunities to lead projects, publish in high-impact journals, and contribute to clinically deployed and commercial-grade systems.
Research & Technical Focus Areas
Applicants should have strong interest and experience in one or more of the following areas:
Technical Areas
Deep learning for medical image analysis (Python, PyTorch)
Multiple instance learning for pathology whole slide images (WSIs)
Classical computer vision
Multimodal data integration for outcome prediction
AI model calibration to real world deployments
Full-stack web development for clinical and research applications (JavaScript, HTML, CSS, Django)
MLOps / DevOps (Docker, Unix-based systems)
Cloud-based deployment and scalable infrastructure (Docker, AWS)
Human-Computer Interaction (HCI) and clinical interface design
Data science and analytics (Python, SQL)
Collaborative software development (GitHub)
Medical AI & Translational Product Development
Automated detection, quantification, and qualitative characterization of cancer cells in blood, bone marrow, H&E tissue, and cytology specimens from whole-slide and microscope images
Clinical outcome prediction using multimodal clinical data (images, genetics, laboratory values, etc.)
Discovery of novel morphologic and computational biomarkers
Transformation of unstructured clinical data into structured datasets
Clinical validation and trials of diagnostic, prognostic, and medical decision-support algorithms
Collaborative Environment
Postdoctoral fellows will work closely with MSKCC clinical services and maintain active collaborations with external partners at UC San Francisco and UC Berkeley Statistics, providing exposure to diverse datasets, methodologies, and interdisciplinary mentorship.
Qualifications
PhD, MD/PhD, or equivalent doctoral degree in computer science, biomedical engineering, computational biology, medical physics, or a related field
Prior experience in deep learning, computer vision, or medical imaging. Experience with pathology images strongly preferred.
Demonstrated ability to conduct independent research and publish in peer-reviewed venues
Demonstrated ability to leverage AI-assisted programming to rapidly prototype, iterate, and deploy beta versions of research tools
Why Join the HemeAI Lab?
Strong translational and clinical deployment focus
Opportunities for first-author publications
Mentorship toward academic, industry, and entrepreneurial career paths
Direct access to large-scale, real-world clinical data
Exposure to regulatory and commercialization pathways
Salary Range $72,000-$87,000
How to Apply
Interested candidates should contact Dr. Gregory Goldgof directly at ****************** with a CV and brief statement of research interests.
Pay Range: $0.00 - $10,000,000.00FSLA Status: Exempt
Closing:
At MSK, we believe in fair, competitive pay that reflects your job, experience, and skills.
MSK is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision.
Federal law requires employers to provide reasonable accommodation to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job. Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment.
$72k-87k yearly Auto-Apply 2d ago
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Postdoctoral Researcher
Memorial Sloan-Kettering Cancer Center 4.1
Doctoral fellow job at Memorial Sloan Kettering Cancer Center
Job details About Us: The people of Memorial Sloan Kettering Cancer Center (MSK) are united by a singular mission: ending cancer for life. Our specialized care teams provide personalized, compassionate, expert care to patients of all ages. Informed by basic research done at our Sloan Kettering Institute, scientists across MSK collaborate to conduct innovative translational and clinical research that is driving a revolution in our understanding of cancer as a disease and improving the ability to prevent, diagnose, and treat it. MSK is dedicated to training the next generation of scientists and clinicians, who go on to pursue our mission at MSK and around the globe.
The Center for Cancer Care Innovation (CCCI) is seeking a highly motivated and skilled Postdoctoral Research Fellow to join our dynamic team. The successful candidate will engage in cutting-edge research aimed at advancing cancer care through innovative technologies and methodologies. The position offers an exciting opportunity to contribute to high-impact research projects and collaborate with leading experts in the field of oncology.
The mission of CCCI is to build the evidence base by designing, testing, and implementing novel models of care that improve cancer care delivery. The center will serve as a hub to connect and train physicians, nurses, scientists, engineers, patients and families in care delivery science and pragmatic trials. Work performed by Center members is expected to result in care delivery innovations that improve quality of life, patient and family experience, costs and efficiency of care, and/or the work life of healthcare providers.
Our group is highly collaborative, both within MSK and outside. The Center seeks to develop a diverse and multi-disciplinary team of students, postdocs and research technicians.
Key areas of focus:
* Research Projects: Conduct independent and collaborative research on cancer care innovations, including but not limited to novel therapeutic strategies, diagnostic tools, and patient management systems.
* Data Analysis: Design and implement experiments, analyze complex data sets, and interpret results to advance the understanding of cancer treatment and care.
* Publication and Dissemination: Prepare manuscripts for publication in peer-reviewed journals, present research findings at conferences, and contribute to grant applications and proposals.
* Collaboration: Work closely with multidisciplinary teams including clinicians, engineers, and data scientists to integrate research findings into practical applications.
* Mentorship: Provide guidance and support to junior researchers and graduate students, fostering a collaborative and productive research environment.
* Innovation: Stay abreast of the latest developments in cancer research and contribute to the development and refinement of innovative approaches and technologies.
The ideal candidate would have:
* An M.D. or Ph.D. in Public Health, Health Services Research, Social Sciences, or related fields
* Experience with or strong interest in mixed methods research, including the integration of quantitative and qualitative data
* Training in or an interest in learning cancer research
* Excellent oral and written communication skills
* Collaborative skills and the ability to work in a team
* Ability to perform self-directed and guided research
* A passion for advancing cancer care through research and innovation is essential
PAY RANGE $72,000 - $87,000
Helpful links:
* MSK Compensation Philosophy
* Review Our Great Benefits Offerings
Pay Range: $0.00 - $10,000,000.00
FSLA Status: Exempt
Closing:
At MSK, we believe in fair, competitive pay that reflects your job, experience, and skills.
MSK is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision.
Federal law requires employers to provide reasonable accommodation to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job. Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment.
Application Process
* 01
Step 1:
Complete an Online Application
* 02
Step 2:
Interview Process
* 03
Step 3:
Provide References
* 04
Step 4:
Extension of Job Offer
* 05
Step 5:
Onboarding
* 06
Step 6:
New Employee Orientation
Postdoctoral Researcher
Department:Academic Program
Location: New York, NY
$72k-87k yearly 48d ago
Postdoctoral Associate | Bradbury Laboratory
Weill Cornell Medicine 4.3
New York, NY jobs
We are seeking a Ph.D. for a Postdoctoral Associate with at least 2 years of experience in cancer immunology and molecular genetics. Specifically, candidates will be expected to be experienced in, but not limited to, genetic engineering approaches, qRT-PCR, cytokine profiling, immunohistochemistry, immunofluorescence, 10+ color immunophenotyping, imaging techniques, and advanced in vitro models (i.e., 3D cultures, organoids). The ideal candidate should have knowledge of ex-vivo immunological assays that can assess activation and functional status of various cell populations within the tumor (or other pathologic) microenvironments. Understanding the immunomodulatory effects associated with an engineered immune and nano-based constructs that promote enhanced therapeutic responses is desirable. Familiarity with theranostic applications in oncology and experience with in vivo immunological procedures is required. The candidate will 1) profile molecular-genetic changes affecting diseased cell populations, as against normal cells, following exposure to immune and/or particle constructs, as well as 2) utilize these readouts to inform desirable in vivo studies and combinatorial treatment strategies. The prospective candidate will be exposed to a dynamic environment focused on product translation to the clinic and will gain invaluable experience across a wide variety of subjects by working closely with a collegial, highly motivated, multidisciplinary team including immunologists, oncologists, pathologists, chemists, and materials scientists. Interested candidates should email their CV and cover letter to ***********************.
Diversity is one of Weill Cornell Medicine's core values and is essential to achieving excellence in research, education and patient care. We welcome applications from candidates who share our commitment to fostering a culture of fairness, equity, and belonging. Weill Cornell Medicine is an Equal Employment Opportunity Employer, providing equal employment opportunities to all qualified applicants without regard to race, sex, sexual orientation, gender identity, national origin, color, age, religion, protected veteran or disability status, or genetic information.
Salary Range (annually): $66,200- $79,551 based on experience.
Weill Cornell Medicine provides the above salary range in compliance with the New York City law on Salary Transparency in Job Advertisements.
The above salary range for New York City based roles represents WCM's good faith and reasonable estimate of possible compensation at the time of posting.
Industry
Hospitals and Health Care
Employment Type
Full-time
$66.2k-79.6k yearly 5d ago
Bioinformatician II - Tisch Cancer Institute BiNGS Core
Mount Sinai Health System 4.4
New York, NY jobs
We are seeking an experienced bioinformatician for the Tisch Cancer Center Bioinformatics for Next Generation Sequencing (BiNGS) shared resource facility, to lead transcriptomics and epigenetics data analysis projects in Cancer biology.
The mission of BiNGS is to enhance scholarship and facilitate NGS data analysis in the ISMMS community by providing access to state-of-the-art tools and training. The BiNGS staff support a broad range of bioinformatics analyses for multiple applications spanning bulk ATAC-, RNA-, and ChIP-seq, CUT&RUN and HiC, single cell ATAC- and RNA-seq, single cell Multiome and Spatial Transcriptomics, WGS and WES. BiNGS further provides services for data management, bioinformatics tools development, access to biocomputing resources, web-based app development, and advanced computational training in data analysis. We are focused on delivering a comprehensive, rapid and user-friendly service.
More specifically, we are working on multiple projects together with PIs in the Tisch Cancer Center and the broader Mount Sinai community to analyze NGS related datasets. For example, we are working to understand the role of RAS mutations in the development of Leukemia utilizing single cell RNA- and ATAC-seq; understand the role of histone variants in cancer development utilizing enhancers analysis, transcriptomic analysis, open chromatin analysis and transcription factor network analysis; in another project, we are utilizing bulk and single cell, and spatial transcriptomics to understand breast cancer metastasis to bone. Finally, we are utilizing FIBER-seq (third generation PacBio long read sequencing), to better understand how chromatin remodelers shape the chromatin landscape.
We are seeking a highly motivated senior Bioinformatic Scientist who wants the opportunity to significantly impact the growth and success of our research programs, the bioinformatics core and the services we provide. The candidate will work closely with investigators to facilitate and enhance the processing of their projects. Commitment to accuracy, high attention-to-details, and ability to work independently are critical competencies for the role. The ability to lead projects and a team of bioinformaticians is a must. We feel that BiNGS presents a unique opportunity for senior bioinformaticians who seek to expand their data analysis skills; their understanding of transcriptional and epigenetic programs and their role in driving cancer initiation, progression and metastasis, and other diseases; their ability to communicate science clearly and efficiently; their ability to lead a small team of junior of bioinformaticians, and their involvement in reducing racial bias in science through mentorship of URM in Science.
M.S. in Bioinformatics, Biomedical Informatics, Computational Biology, or Genomics. Alternately, M.S. in a discipline requiring strong computational and analytical skills supplemented with some biology exposure. Ph.D in a related field preferred. Those with a Bachelors degree and additional post-graduate experience are considered.
2+ years post-graduate experience in a research environment, including the manipulation of large biological datasets.
Advanced knowledge of genetics and/or statistical analysis software and online resources. Experience in programming environments such as MatLab, R statistical package, BioConductor, Perl and C++.
Preferred Skillset
MSc or PhD in bioinformatics, computer Sciences or related fields
Proven experience in analyzing bulk RNA- and ATAC-seq, sc RNA-seq, sc ATAC-seq, and sc Multiome
Proven experience with Python, R and Linux. Additional experience with standard genomics tools for high-throughput sequencing data analysis (e.g. Bowtie2, Cellranger, Samtools, STAR, MACS2, Seurat, Signac, Cicero, Chromvar, Scenicplus and the UCSC genome browser).
Experience with markup languages such as HTML is preferred.
Proven ability to work on the AWS cloud.
Experience in bash HPC cluster environment with a parallel file system.
Proven ability to research, analyze, recommend, communicate, and implement solutions.
Good understanding of chromatin biology, and NGS technologies
Must be able to work as an individual while part of a small team.
Non-Bargaining Unit, 824 - Oncological Sciences - ISM, Icahn School of Medicine
Execute computational analysis for bulk RNA- and ATAC-seq, sc RNA-seq, sc ATAC-seq, and sc Multiome.
Developing, tracking and reporting of ongoing projects including presentation of analysis progress in internal meetings and communications with PI to present results, interpret data and come up with new hypotheses.
Integrate data across different datatypes and from publicly available resources (e.g., ENCODE and TCGA), with experimental data generated by PIs. For example, correlation with gene expression signatures, and Histone PTM enrichment analysis. The ideal candidate will be able to navigate the available datasets and extract meaningful data based on the system he/she works on.
Provide analyses and visualization for presentations and publications.
Participate in the implementation of new software tools (e.g., MOFA and SNF) to process, analyze and visualize high-throughput multidimensional sequencing data. The candidate will be required to identify the main requirements based on relevant questions, identify available tools, implement and test.
Manage data and interactive tools on local HPC and commercially available clouds preferably Amazon Web Services. The candidate will execute all data analysis on HPC using bash and manage the storage and archiving of all NGS datasets on the MSSM HPC. Further managing of our HTML reports will be done on Amazon cloud
Provide training to TCC investigators and trainees.
$69k-95k yearly est. Auto-Apply 60d+ ago
Bioinformatician II- Tisch Cancer Institute BiNGS Core
Mount Sinai Health System 4.4
New York, NY jobs
We are seeking an experienced bioinformatician for the Tisch Cancer Center Bioinformatics for Next Generation Sequencing (BiNGS) shared resource facility, to lead transcriptomics and epigenetics data analysis projects in Cancer biology.
The mission of BiNGS is to enhance scholarship and facilitate NGS data analysis in the ISMMS community by providing access to state-of-the-art tools and training. The BiNGS staff support a broad range of bioinformatics analyses for multiple applications spanning bulk ATAC-, RNA-, and ChIP-seq, CUT&RUN and HiC, single cell ATAC- and RNA-seq, single cell Multiome and Spatial Transcriptomics, WGS and WES. BiNGS further provides services for data management, bioinformatics tools development, access to biocomputing resources, web-based app development, and advanced computational training in data analysis. We are focused on delivering a comprehensive, rapid and user-friendly service.
More specifically, we are working on multiple projects together with PIs in the Tisch Cancer Center and the broader Mount Sinai community to analyze NGS related datasets. For example, we are working to understand the role of RAS mutations in the development of Leukemia utilizing single cell RNA- and ATAC-seq; understand the role of histone variants in cancer development utilizing enhancers analysis, transcriptomic analysis, open chromatin analysis and transcription factor network analysis; in another project, we are utilizing bulk and single cell, and spatial transcriptomics to understand breast cancer metastasis to bone. Finally, we are utilizing FIBER-seq (third generation PacBio long read sequencing), to better understand how chromatin remodelers shape the chromatin landscape.
We are seeking a highly motivated senior Bioinformatic Scientist who wants the opportunity to significantly impact the growth and success of our research programs, the bioinformatics core and the services we provide. The candidate will work closely with investigators to facilitate and enhance the processing of their projects. Commitment to accuracy, high attention-to-details, and ability to work independently are critical competencies for the role. The ability to lead projects and a team of bioinformaticians is a must. We feel that BiNGS presents a unique opportunity for senior bioinformaticians who seek to expand their data analysis skills; their understanding of transcriptional and epigenetic programs and their role in driving cancer initiation, progression and metastasis, and other diseases; their ability to communicate science clearly and efficiently; their ability to lead a small team of junior of bioinformaticians, and their involvement in reducing racial bias in science through mentorship of URM in Science.
M.S. in Bioinformatics, Biomedical Informatics, Computational Biology, or Genomics. Alternately, M.S. in a discipline requiring strong computational and analytical skills supplemented with some biology exposure. Ph.D in a related field preferred. Those with a Bachelors degree and additional post-graduate experience are considered.
2+ years post-graduate experience in a research environment, including the manipulation of large biological datasets.
Advanced knowledge of genetics and/or statistical analysis software and online resources. Experience in programming environments such as MatLab, R statistical package, BioConductor, Perl and C++.
Preferred Skills
MSc or PhD in bioinformatics, computer Sciences or related fields.
Proven experience in analyzing bulk RNA- and ATAC-seq, sc RNA-seq, sc ATAC-seq, and sc Multiome.
Proven experience with Python, R and Linux. Additional experience with standard genomics tools for high-throughput sequencing data analysis (e.g. Bowtie2, Cellranger, Samtools, STAR, MACS2, Seurat, Signac, Cicero, Chromvar, Scenicplus and the UCSC genome browser).
Experience with markup languages such as HTML is preferred.
Proven ability to work on the AWS cloud.
Experience in bash HPC cluster environment with a parallel file system.
Proven ability to research, analyze, recommend, communicate, and implement solutions.
Good understanding of chromatin biology, and NGS technologies.
Must be able to work as an individual while part of a small team.
Execute computational analysis for bulk RNA- and ATAC-seq, sc RNA-seq, sc ATAC-seq, and sc Multiome.
Developing, tracking and reporting of ongoing projects including presentation of analysis progress in internal meetings and communications with PI to present results, interpret data and come up with new hypotheses.
Integrate data across different datatypes and from publicly available resources (e.g., ENCODE and TCGA), with experimental data generated by PIs. For example, correlation with gene expression signatures, and Histone PTM enrichment analysis. The ideal candidate will be able to navigate the available datasets and extract meaningful data based on the system he/she works on.
Provide analyses and visualization for presentations and publications.
Participate in the implementation of new software tools (e.g., MOFA and SNF) to process, analyze and visualize high-throughput multidimensional sequencing data.
The candidate will be required to identify the main requirements based on relevant questions, identify
available tools, implement and test.
PManage data and interactive tools on local HPC and commercially available clouds preferably Amazon Web Services. The candidate will execute all data analysis on HPC using bash and manage the storage and archiving of all NGS datasets on the MSSM HPC.
Further managing of our HTML reports will be done on Amazon cloud
Provide training to TCC investigators and trainees.
$69k-95k yearly est. Auto-Apply 10d ago
Bioinformatician II - Hematology & Medical Oncology
Mount Sinai Health System 4.4
New York, NY jobs
The Bioinformatician II partners with researchers/biologists from the Mount Sinai Department of Genetics and Genomic Sciences on innovative genomic analyses of structural variation, epigenetics, and gene expression in an integrated environment combining experimental and bioinformatic approaches to human disease. S/he leads a variety of projects and gains exposure to many productive areas of research, and develops/supports multiple research projects by delivering bioinformatics services for bio-medical data from cutting-edge genomic technologies.
This incumbent performs the role of database developer for Varimpact, building a comprehensive impact database of genetic variants through text mining. This database consists of genetic variants with gene, protein, pathway, cellular, drug level functional impact and is a tool to search and highlight genetic variants, drugs and diseases in 30 million abstracts and 3 million full texts.
M.S. in Bioinformatics, Biomedical Informatics, Computational Biology, or Genomics. Alternately, M.S. in a discipline requiring strong computational and analytical skills supplemented with some biology exposure. Ph.D in a related field preferred. Those with a Bachelors degree and additional post-graduate experience are considered.
2+ years post-graduate experience in a research environment, including the manipulation of large biological datasets.
Advanced knowledge of genetics and/or statistical analysis software and online resources. Experience in programming environments such as MatLab, R statistical package, BioConductor, Perl and C++.
Develops and may perform a lead role for a variety of bioinformatics analysis projects, including development of Varimpact, an impact database of generic variants.
Writes custom scripts for analysis of genomic data derived from high-throughput techniques.
Manages databases, conducts statistical and genomic analysis, and participates in the preparation of manuscripts and presentations.
Collaborates with wet-bench biologists and works independently to analyze data derived from several types of projects using microarrays and high-throughput sequencing.
Conducts analysis of microarray and high-throughput sequencing data, genome sequence analysis, experimental design and statistical analysis.
Performs quality control and analysis.
Other related duties as assigned.
$69k-95k yearly est. Auto-Apply 60d+ ago
Bioinformatician II - Psychiatry
Mount Sinai Health System 4.4
New York, NY jobs
The Center for Disease Neurogenomics (CDN) at the Icahn School of Medicine at Mount Sinai is seeking a proactive and detail-oriented Bioinformatician II to join a multidisciplinary team supporting the analysis, infrastructure, and data stewardship of large-scale functional genomics datasets. This position is intended for candidates with practical experience managing omics data, maintaining computational infrastructure, and developing efficient solutions to support high-throughput data processing and secure storage.
M.S. in Bioinformatics, Biomedical Informatics, Computational Biology, or Genomics. Alternately, M.S. in a discipline requiring strong computational and analytical skills supplemented with some biology exposure. Ph.D in a related field preferred. Those with a Bachelors degree and additional post-graduate experience are considered.
2+ years post-graduate experience in a research environment, including the manipulation of large biological datasets.; with ≥3 years of experience preferred
Advanced knowledge of genetics and/or statistical analysis software and online resources. Experience in programming environments such as MatLab, R statistical package, BioConductor, Perl and C++.
Proficiency in Python and R; working knowledge of SQL and Linux shell scripting.
Experience processing large-scale omics data (RNA-seq, ATAC-seq, or WGS).
Experience using or developing Nextflow or Snakemake-based pipelines is a strong plus.
Strong problem-solving skills, ability to prioritize, and attention to reproducibility and data integrity.
Preferred Qualifications:
Demonstrated experience maintaining or developing data tracking systems or LIMS solutions.
Familiarity with HPC environments and workload managers (e.g., LSF, SLURM).
Experience with cloud-based genomics analysis platforms such as CAVATICA, Verily Workbench, Google Cloud Platform (GCP), Amazon Web Services (AWS), or comparable environments.
Experience with data privacy standards and compliance in biomedical datasets.
Assist in the preprocessing, demultiplexing, and quality control of single-cell and bulk sequencing data across multiple assays (RNA-seq, ATAC-seq, multiome).
Implement and maintain metadata infrastructure for tracking donor/sample provenance and cohort selection across projects using a relational database backend.
Monitor and maintain local high-performance computing resources, including scripting of automated usage summaries, quota alerts, and issue tracking.
Support data transfers, pipeline execution, and user coordination in hybrid cloud environments (e.g., CAVATICA, GCP).
Write and maintain robust, well-documented code (e.g., Snakemake, bash, R, Python) for processing and managing large-scale datasets.
Respond to infrastructure incidents (e.g., disk quota overflows, data loss risks) and proactively implement safeguards.
Contribute to documentation and training materials to enable team-wide system usage.
Other related duties as assigned.
$69k-95k yearly est. Auto-Apply 60d+ ago
Bioinformatician II- Tisch Cancer Institute BiNGS Core
Mount Sinai Health System 4.4
New York, NY jobs
We are seeking an experienced bioinformatician for the Tisch Cancer Center Bioinformatics for Next Generation Sequencing (BiNGS) shared resource facility, to lead transcriptomics and epigenetics data analysis projects in Cancer biology. The mission of BiNGS is to enhance scholarship and facilitate NGS data analysis in the ISMMS community by providing access to state-of-the-art tools and training. The BiNGS staff support a broad range of bioinformatics analyses for multiple applications spanning bulk ATAC-, RNA-, and ChIP-seq, CUT&RUN and HiC, single cell ATAC- and RNA-seq, single cell Multiome and Spatial Transcriptomics, WGS and WES. BiNGS further provides services for data management, bioinformatics tools development, access to biocomputing resources, web-based app development, and advanced computational training in data analysis. We are focused on delivering a comprehensive, rapid and user-friendly service.
More specifically, we are working on multiple projects together with PIs in the Tisch Cancer Center and the broader Mount Sinai community to analyze NGS related datasets. For example, we are working to understand the role of RAS mutations in the development of Leukemia utilizing single cell RNA- and ATAC-seq; understand the role of histone variants in cancer development utilizing enhancers analysis, transcriptomic analysis, open chromatin analysis and transcription factor network analysis; in another project, we are utilizing bulk and single cell, and spatial transcriptomics to understand breast cancer metastasis to bone. Finally, we are utilizing FIBER-seq (third generation PacBio long read sequencing), to better understand how chromatin remodelers shape the chromatin landscape.
We are seeking a highly motivated senior Bioinformatic Scientist who wants the opportunity to significantly impact the growth and success of our research programs, the bioinformatics core and the services we provide. The candidate will work closely with investigators to facilitate and enhance the processing of their projects. Commitment to accuracy, high attention-to-details, and ability to work independently are critical competencies for the role. The ability to lead projects and a team of bioinformaticians is a must. We feel that BiNGS presents a unique opportunity for senior bioinformaticians who seek to expand their data analysis skills; their understanding of transcriptional and epigenetic programs and their role in driving cancer initiation, progression and metastasis, and other diseases; their ability to communicate science clearly and efficiently; their ability to lead a small team of junior of bioinformaticians, and their involvement in reducing racial bias in science through mentorship of URM in Science.
**Qualifications**
+ M.S. in Bioinformatics, Biomedical Informatics, Computational Biology, or Genomics. Alternately, M.S. in a discipline requiring strong computational and analytical skills supplemented with some biology exposure. Ph.D in a related field preferred. Those with a Bachelors degree and additional post-graduate experience are considered.
+ 2+ years post-graduate experience in a research environment, including the manipulation of large biological datasets.
+ Advanced knowledge of genetics and/or statistical analysis software and online resources. Experience in programming environments such as MatLab, R statistical package, BioConductor, Perl and C++.
Preferred Skills
+ MSc or PhD in bioinformatics, computer Sciences or related fields.
+ Proven experience in analyzing bulk RNA- and ATAC-seq, sc RNA-seq, sc ATAC-seq, and sc Multiome.
+ Proven experience with Python, R and Linux. Additional experience with standard genomics tools for high-throughput sequencing data analysis (e.g. Bowtie2, Cellranger, Samtools, STAR, MACS2, Seurat, Signac, Cicero, Chromvar, Scenicplus and the UCSC genome browser).
+ Experience with markup languages such as HTML is preferred.
+ Proven ability to work on the AWS cloud.
+ Experience in bash HPC cluster environment with a parallel file system.
+ Proven ability to research, analyze, recommend, communicate, and implement solutions.
+ Good understanding of chromatin biology, and NGS technologies.
+ Must be able to work as an individual while part of a small team.
**Responsibilities**
+ Execute computational analysis for bulk RNA- and ATAC-seq, sc RNA-seq, sc ATAC-seq, and sc Multiome.
+ Developing, tracking and reporting of ongoing projects including presentation of analysis progress in internal meetings and communications with PI to present results, interpret data and come up with new hypotheses.
+ Integrate data across different datatypes and from publicly available resources (e.g., ENCODE and TCGA), with experimental data generated by PIs. For example, correlation with gene expression signatures, and Histone PTM enrichment analysis. The ideal candidate will be able to navigate the available datasets and extract meaningful data based on the system he/she works on.
+ Provide analyses and visualization for presentations and publications.
+ Participate in the implementation of new software tools (e.g., MOFA and SNF) to process, analyze and visualize high-throughput multidimensional sequencing data.
+ The candidate will be required to identify the main requirements based on relevant questions, identifyavailable tools, implement and test.
+ PManage data and interactive tools on local HPC and commercially available clouds preferably Amazon Web Services. The candidate will execute all data analysis on HPC using bash and manage the storage and archiving of all NGS datasets on the MSSM HPC.
+ Further managing of our HTML reports will be done on Amazon cloud
+ Provide training to TCC investigators and trainees.
**About Us**
**Strength through Unity and Inclusion**
The Mount Sinai Health System is committed to fostering an environment where everyone can contribute to excellence. We share a common dedication to delivering outstanding patient care. When you join us, you become part of Mount Sinai's unparalleled legacy of achievement, education, and innovation as we work together to transform healthcare. We encourage all team members to actively participate in creating a culture that ensures fair access to opportunities, promotes inclusive practices, and supports the success of every individual.
At Mount Sinai, our leaders are committed to fostering a workplace where all employees feel valued, respected, and empowered to grow. We strive to create an environment where collaboration, fairness, and continuous learning drive positive change, improving the well-being of our staff, patients, and organization. Our leaders are expected to challenge outdated practices, promote a culture of respect, and work toward meaningful improvements that enhance patient care and workplace experiences. We are dedicated to building a supportive and welcoming environment where everyone has the opportunity to thrive and advance professionally. Explore this opportunity and be part of the next chapter in our history.
**About the Mount Sinai Health System:**
Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time - discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients' medical and emotional needs at the center of all treatment. The Health System includes more than 9,000 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked: No. 1 in Geriatrics, top 5 in Cardiology/Heart Surgery, and top 20 in Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report's "Best Children's Hospitals" ranks Mount Sinai Kravis Children's Hospital among the country's best in several pediatric specialties. The Icahn School of Medicine at Mount Sinai is ranked No. 11 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges. Newsweek's "The World's Best Smart Hospitals" ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally.
**Equal Opportunity Employer**
The Mount Sinai Health System is an equal opportunity employer, complying with all applicable federal civil rights laws. We do not discriminate, exclude, or treat individuals differently based on race, color, national origin, age, religion, disability, sex, sexual orientation, gender, veteran status, or any other characteristic protected by law. We are deeply committed to fostering an environment where all faculty, staff, students, trainees, patients, visitors, and the communities we serve feel respected and supported. Our goal is to create a healthcare and learning institution that actively works to remove barriers, address challenges, and promote fairness in all aspects of our organization.
**Compensation Statement**
Mount Sinai Health System (MSHS) provides a salary range to comply with the New York City Law on Salary Transparency in Job Advertisements. The salary range for the role is $65885 - $100000 Annually. Actual salaries depend on a variety of factors, including experience, education, and hospital need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits.
$65.9k-100k yearly 10d ago
Bioinformatician II - Tisch Cancer Institute BiNGS Core
Mount Sinai Health System 4.4
New York, NY jobs
We are seeking an experienced bioinformatician for the Tisch Cancer Center Bioinformatics for Next Generation Sequencing (BiNGS) shared resource facility, to lead transcriptomics and epigenetics data analysis projects in Cancer biology. The mission of BiNGS is to enhance scholarship and facilitate NGS data analysis in the ISMMS community by providing access to state-of-the-art tools and training. The BiNGS staff support a broad range of bioinformatics analyses for multiple applications spanning bulk ATAC-, RNA-, and ChIP-seq, CUT&RUN and HiC, single cell ATAC- and RNA-seq, single cell Multiome and Spatial Transcriptomics, WGS and WES. BiNGS further provides services for data management, bioinformatics tools development, access to biocomputing resources, web-based app development, and advanced computational training in data analysis. We are focused on delivering a comprehensive, rapid and user-friendly service.
More specifically, we are working on multiple projects together with PIs in the Tisch Cancer Center and the broader Mount Sinai community to analyze NGS related datasets. For example, we are working to understand the role of RAS mutations in the development of Leukemia utilizing single cell RNA- and ATAC-seq; understand the role of histone variants in cancer development utilizing enhancers analysis, transcriptomic analysis, open chromatin analysis and transcription factor network analysis; in another project, we are utilizing bulk and single cell, and spatial transcriptomics to understand breast cancer metastasis to bone. Finally, we are utilizing FIBER-seq (third generation PacBio long read sequencing), to better understand how chromatin remodelers shape the chromatin landscape.
We are seeking a highly motivated senior Bioinformatic Scientist who wants the opportunity to significantly impact the growth and success of our research programs, the bioinformatics core and the services we provide. The candidate will work closely with investigators to facilitate and enhance the processing of their projects. Commitment to accuracy, high attention-to-details, and ability to work independently are critical competencies for the role. The ability to lead projects and a team of bioinformaticians is a must. We feel that BiNGS presents a unique opportunity for senior bioinformaticians who seek to expand their data analysis skills; their understanding of transcriptional and epigenetic programs and their role in driving cancer initiation, progression and metastasis, and other diseases; their ability to communicate science clearly and efficiently; their ability to lead a small team of junior of bioinformaticians, and their involvement in reducing racial bias in science through mentorship of URM in Science.
**Qualifications**
+ M.S. in Bioinformatics, Biomedical Informatics, Computational Biology, or Genomics. Alternately, M.S. in a discipline requiring strong computational and analytical skills supplemented with some biology exposure. Ph.D in a related field preferred. Those with a Bachelors degree and additional post-graduate experience are considered.
+ 2+ years post-graduate experience in a research environment, including the manipulation of large biological datasets.
+ Advanced knowledge of genetics and/or statistical analysis software and online resources. Experience in programming environments such as MatLab, R statistical package, BioConductor, Perl and C++.
Preferred Skillset
+ MSc or PhD in bioinformatics, computer Sciences or related fields
+ Proven experience in analyzing bulk RNA- and ATAC-seq, sc RNA-seq, sc ATAC-seq, and sc Multiome
+ Proven experience with Python, R and Linux. Additional experience with standard genomics tools for high-throughput sequencing data analysis (e.g. Bowtie2, Cellranger, Samtools, STAR, MACS2, Seurat, Signac, Cicero, Chromvar, Scenicplus and the UCSC genome browser).
+ Experience with markup languages such as HTML is preferred.
+ Proven ability to work on the AWS cloud.
+ Experience in bash HPC cluster environment with a parallel file system.
+ Proven ability to research, analyze, recommend, communicate, and implement solutions.
+ Good understanding of chromatin biology, and NGS technologies
+ Must be able to work as an individual while part of a small team.
Non-Bargaining Unit, 824 - Oncological Sciences - ISM, Icahn School of Medicine
**Responsibilities**
+ Execute computational analysis for bulk RNA- and ATAC-seq, sc RNA-seq, sc ATAC-seq, and sc Multiome.
+ Developing, tracking and reporting of ongoing projects including presentation of analysis progress in internal meetings and communications with PI to present results, interpret data and come up with new hypotheses.
+ Integrate data across different datatypes and from publicly available resources (e.g., ENCODE and TCGA), with experimental data generated by PIs. For example, correlation with gene expression signatures, and Histone PTM enrichment analysis. The ideal candidate will be able to navigate the available datasets and extract meaningful data based on the system he/she works on.
+ Provide analyses and visualization for presentations and publications.
+ Participate in the implementation of new software tools (e.g., MOFA and SNF) to process, analyze and visualize high-throughput multidimensional sequencing data. The candidate will be required to identify the main requirements based on relevant questions, identify available tools, implement and test.
+ Manage data and interactive tools on local HPC and commercially available clouds preferably Amazon Web Services. The candidate will execute all data analysis on HPC using bash and manage the storage and archiving of all NGS datasets on the MSSM HPC. Further managing of our HTML reports will be done on Amazon cloud
+ Provide training to TCC investigators and trainees.
**About Us**
**Strength through Unity and Inclusion**
The Mount Sinai Health System is committed to fostering an environment where everyone can contribute to excellence. We share a common dedication to delivering outstanding patient care. When you join us, you become part of Mount Sinai's unparalleled legacy of achievement, education, and innovation as we work together to transform healthcare. We encourage all team members to actively participate in creating a culture that ensures fair access to opportunities, promotes inclusive practices, and supports the success of every individual.
At Mount Sinai, our leaders are committed to fostering a workplace where all employees feel valued, respected, and empowered to grow. We strive to create an environment where collaboration, fairness, and continuous learning drive positive change, improving the well-being of our staff, patients, and organization. Our leaders are expected to challenge outdated practices, promote a culture of respect, and work toward meaningful improvements that enhance patient care and workplace experiences. We are dedicated to building a supportive and welcoming environment where everyone has the opportunity to thrive and advance professionally. Explore this opportunity and be part of the next chapter in our history.
**About the Mount Sinai Health System:**
Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time - discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients' medical and emotional needs at the center of all treatment. The Health System includes more than 9,000 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked: No. 1 in Geriatrics, top 5 in Cardiology/Heart Surgery, and top 20 in Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report's "Best Children's Hospitals" ranks Mount Sinai Kravis Children's Hospital among the country's best in several pediatric specialties. The Icahn School of Medicine at Mount Sinai is ranked No. 11 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges. Newsweek's "The World's Best Smart Hospitals" ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally.
**Equal Opportunity Employer**
The Mount Sinai Health System is an equal opportunity employer, complying with all applicable federal civil rights laws. We do not discriminate, exclude, or treat individuals differently based on race, color, national origin, age, religion, disability, sex, sexual orientation, gender, veteran status, or any other characteristic protected by law. We are deeply committed to fostering an environment where all faculty, staff, students, trainees, patients, visitors, and the communities we serve feel respected and supported. Our goal is to create a healthcare and learning institution that actively works to remove barriers, address challenges, and promote fairness in all aspects of our organization.
**Compensation Statement**
Mount Sinai Health System (MSHS) provides a salary range to comply with the New York City Law on Salary Transparency in Job Advertisements. The salary range for the role is $65885 - $100000 Annually. Actual salaries depend on a variety of factors, including experience, education, and hospital need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits.
$65.9k-100k yearly 60d+ ago
Bioinformatician II - Psychiatry
Mount Sinai Health System 4.4
New York, NY jobs
The Center for Disease Neurogenomics (CDN) at the Icahn School of Medicine at Mount Sinai is seeking a proactive and detail-oriented Bioinformatician II to join a multidisciplinary team supporting the analysis, infrastructure, and data stewardship of large-scale functional genomics datasets. This position is intended for candidates with practical experience managing omics data, maintaining computational infrastructure, and developing efficient solutions to support high-throughput data processing and secure storage.
**Qualifications**
+ M.S. in Bioinformatics, Biomedical Informatics, Computational Biology, or Genomics. Alternately, M.S. in a discipline requiring strong computational and analytical skills supplemented with some biology exposure. Ph.D in a related field preferred. Those with a Bachelors degree and additional post-graduate experience are considered.
+ 2+ years post-graduate experience in a research environment, including the manipulation of large biological datasets.; with ≥3 years of experience preferred
+ Advanced knowledge of genetics and/or statistical analysis software and online resources. Experience in programming environments such as MatLab, R statistical package, BioConductor, Perl and C++.
+ Proficiency in Python and R; working knowledge of SQL and Linux shell scripting.
+ Experience processing large-scale omics data (RNA-seq, ATAC-seq, or WGS).
+ Experience using or developing Nextflow or Snakemake-based pipelines is a strong plus.
+ Strong problem-solving skills, ability to prioritize, and attention to reproducibility and data integrity.
+ Preferred Qualifications:
+ Demonstrated experience maintaining or developing data tracking systems or LIMS solutions.
+ Familiarity with HPC environments and workload managers (e.g., LSF, SLURM).
+ Experience with cloud-based genomics analysis platforms such as CAVATICA, Verily Workbench, Google Cloud Platform (GCP), Amazon Web Services (AWS), or comparable environments.
+ Experience with data privacy standards and compliance in biomedical datasets.
**Responsibilities**
+ Assist in the preprocessing, demultiplexing, and quality control of single-cell and bulk sequencing data across multiple assays (RNA-seq, ATAC-seq, multiome).
+ Implement and maintain metadata infrastructure for tracking donor/sample provenance and cohort selection across projects using a relational database backend.
+ Monitor and maintain local high-performance computing resources, including scripting of automated usage summaries, quota alerts, and issue tracking.
+ Support data transfers, pipeline execution, and user coordination in hybrid cloud environments (e.g., CAVATICA, GCP).
+ Write and maintain robust, well-documented code (e.g., Snakemake, bash, R, Python) for processing and managing large-scale datasets.
+ Respond to infrastructure incidents (e.g., disk quota overflows, data loss risks) and proactively implement safeguards.
+ Contribute to documentation and training materials to enable team-wide system usage.
+ Other related duties as assigned.
**About Us**
**Strength through Unity and Inclusion**
The Mount Sinai Health System is committed to fostering an environment where everyone can contribute to excellence. We share a common dedication to delivering outstanding patient care. When you join us, you become part of Mount Sinai's unparalleled legacy of achievement, education, and innovation as we work together to transform healthcare. We encourage all team members to actively participate in creating a culture that ensures fair access to opportunities, promotes inclusive practices, and supports the success of every individual.
At Mount Sinai, our leaders are committed to fostering a workplace where all employees feel valued, respected, and empowered to grow. We strive to create an environment where collaboration, fairness, and continuous learning drive positive change, improving the well-being of our staff, patients, and organization. Our leaders are expected to challenge outdated practices, promote a culture of respect, and work toward meaningful improvements that enhance patient care and workplace experiences. We are dedicated to building a supportive and welcoming environment where everyone has the opportunity to thrive and advance professionally. Explore this opportunity and be part of the next chapter in our history.
**About the Mount Sinai Health System:**
Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time - discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients' medical and emotional needs at the center of all treatment. The Health System includes more than 9,000 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked: No. 1 in Geriatrics, top 5 in Cardiology/Heart Surgery, and top 20 in Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report's "Best Children's Hospitals" ranks Mount Sinai Kravis Children's Hospital among the country's best in several pediatric specialties. The Icahn School of Medicine at Mount Sinai is ranked No. 11 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges. Newsweek's "The World's Best Smart Hospitals" ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally.
**Equal Opportunity Employer**
The Mount Sinai Health System is an equal opportunity employer, complying with all applicable federal civil rights laws. We do not discriminate, exclude, or treat individuals differently based on race, color, national origin, age, religion, disability, sex, sexual orientation, gender, veteran status, or any other characteristic protected by law. We are deeply committed to fostering an environment where all faculty, staff, students, trainees, patients, visitors, and the communities we serve feel respected and supported. Our goal is to create a healthcare and learning institution that actively works to remove barriers, address challenges, and promote fairness in all aspects of our organization.
**Compensation Statement**
Mount Sinai Health System (MSHS) provides a salary range to comply with the New York City Law on Salary Transparency in Job Advertisements. The salary range for the role is $65885 - $100000 Annually. Actual salaries depend on a variety of factors, including experience, education, and hospital need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits.
$65.9k-100k yearly 60d+ ago
Pharmacovigilance Scientist
Axsome Therapeutics, Inc. 3.6
New York, NY jobs
Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain's biggest problems so patients and their loved ones can flourish. For more information, please visit us at ************** and follow us on LinkedIn and X.
About This Role
Axsome Therapeutics is seeking a Pharmacovigilance Scientist to establish and execute pharmacovigilance (PV) systems and procedures, with a strong focus on maintaining high-quality standards. This role is responsible for supporting the Pharmacovigilance (PV) Science function under the guidance of the PV physician and providing oversight of ICSR assessment, signal detection, medical surveillance and risk management activities for investigational products in clinical development and marketed products. This position collaborates with key internal stakeholders, including Clinical Development, Commercial, Medical Information, Medical Affairs, Quality, Regulatory and Legal, as well as multiple external Service Providers and partners on pharmacovigilance-related matters.
This position reports to Executive Director of Pharmacovigilance/Drug Safety and is based at Axsome's HQ in New York City with an on-site requirement of at least three days per week. We are unable to consider candidates who are looking for fully remote roles.
Job Responsibilities and Duties include, but are not limited to, the following:
* Assist safety physician to enhance safety surveillance and signal detection by monitoring and analyzing safety data from various sources to identify potential safety signals or trends related to investigational and marketed products
* Contribute to the creation and execution of risk minimization measures to mitigate identified risks.
* Support the preparation pharmacovigilance aggregate safety reports (e.g., PADER, PSURs, DSURs) to regulatory authorities to meet compliance requirements.
* Collaborate with PV physician/PV operations and key stakeholders to request/receive applicable sections of the report
* Provide training and guidance to other functions to address ad hoc questions and issues
* Ensure timely finalization of the reports to meet the submission timelines of relevant health authorities and other external stakeholders
* Collaborate and communicate with cross-functional teams to ensure effective safety monitoring and communication
* Support the safety review team (SRT) and coordinates all safety topic discussion and documentation.
* Ensure appropriate stakeholder representation and input at SRT
* Ensure all data is appropriately compiled and presented at SRT for team review
* Liaise with SRT chair to facilitate communication and support for decisions resulting from the SRT (e.g. update of RMPs, labeling, regulatory notifications etc.)
* Contribute to clinical trials by providing safety input and reviewing documents such as Clinical Study Reports (CSRs), protocols, and investigator brochures (IB), ICF etc.
* Provide support for the processing of individual case safety reports (ICSRs) and ensure data accuracy and completeness for investigational and marketed products
* Support the PV SOP updates
* Oversee vendor safety process, e.g., signal detection, validation and assessment.
* Participate in audit/inspection preparedness activities and provide support during regulatory inspections in collaboration with team members
* Participate in new study initiation to ensure PV requirements are met including but not limited to safety reporting, query resolution, SAR reconciliation, un-blinding process, and safety reporting training
* Evaluate and improve current PV processes, as needed, to strengthen medical surveillance and risk management process ensuring alignment with best practices
Requirements / Qualifications
* Master's degree in health-discipline or equivalent required, RN, R.Ph, or Pharm D degree is highly preferred
* 5+ years of progressively responsible Pharmacovigilance experience in a pharmaceutical, biotechnology, or related environment with focused experience in signal detection, safety surveillance, risk mitigation and risk management
* Extensive experience in case processing, regulatory requirements of ICSRs, MedDRA, WHODD, project management
* Experience in submission activities in both FDA and EU is preferred, but not required
* Must demonstrate the ability to draft reports, business correspondence, and procedures, and to effectively present information and respond to questions from internal and external stakeholders, both domestic and international
* Ability to work on site Monday, Tuesday & Thursday. We are unable to consider candidates who are looking for fully remote roles.
Experience and Knowledge
* Knowledge of ICH E2B(R2) and (R3) specifications and entry guidance.
* Knowledge of global pharmacovigilance reporting rules and timelines, including but not limited to Health Canada, FDA and EMA.
* Knowledge of relevant food and drug administration (FDA), European union (EU) and international conference on Harmonization (ICH) guidelines, initiatives, and regulations governing pharmacovigilance.
* Ability to interpret health and medical records such as adverse event reporting forms, a discharge summary, etc.
* Experience with clinical and/or post-marketing case assessment, including medical terminologies, MedDRA and WHO DD coding and narrative writing.
* Experience with safety database is required; ARISg is a plus but not mandatory.
* Experience with Veeva is a plus but not mandatory.
* Ability to work independently and collaboratively, as required, in a fast-paced matrixed team environment consisting of internal and external team members
* Analytical thinker with excellent problem-solving skills and the ability to adapt to changing priorities and deadlines
* Ability to read, analyze, and interpret professional journals, technical procedures, and governmental regulations
* Excellent planning, organization, and time management skills including the ability to support and prioritize multiple projects
* Excellent verbal and written communication and skills
* Excellent in detailed-oriented tasks.
Salary & Benefits
The anticipated salary range for this role is $150,000 - $185,000. We encourage candidates of all levels to apply as there may be flexibility on final job title and responsibilities. The salary offer will be based on a variety of factors, including experience, qualifications, internal equity and location. Axsome offers a competitive employment package that includes an annual bonus, significant equity and a generous benefits package.
Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. We value and encourage diversity and solicit applications from all qualified applicants without regard to race, color, gender, sex, age, religion, creed, national origin, sexual orientation, gender identity, ancestry, citizenship, marital status, physical or mental disability, medical condition, veteran status, genetic information, or any other characteristic protected by federal, state, or local law.
Axsome Therapeutics does not accept unsolicited resumes from recruiters or third-party recruitment agencies and will not pay placement fees for unsolicited candidates that are sent to hiring managers, the HR team or other Axsome team members. Only approved vendors who have been explicitly asked to support a specific search will receive access to our Applicant Tracking System to submit candidates for consideration.
$150k-185k yearly 60d+ ago
Research Scientist ll
Health Research, Inc. 4.5
Menands, NY jobs
Applications to be submitted by January 27, 2026
Compensation Grade:
P22
Compensation Details:
Minimum: $81,696.00 - Maximum: $81,696.00 Annually
Positions with a designated work location in New York City, Nassau, Rockland, Suffolk, or Westchester Counties will receive a $4,000 annual downstate adjustment (pro-rated for part-time positions).
Department
(OPH) CCH - Division of Chronic Disease Prevention - Bureau of Cancer Epidemiology
Job Description:
Responsibilities
Health Research, Inc. is seeking a Research Scientist II to work as part of the Bureau of Cancer Epidemiology's analysis and output unit. The incumbent will be responsible for data analysis using New York State Cancer Registry (NYSCR) data and linked data sources to improve understanding of cancer patterns in NYS. The incumbent will participate in research and evaluation projects using NYSCR data, including the design, analysis, interpretation, and presentation of findings. Research and evaluation projects will address multiple aspects of cancer epidemiology including incidence, stage at diagnosis, treatment, survival, and mortality. The incumbent will also interact with external researchers to provide guidance regarding use of NYSCR data for research and to collaborate on approved projects. Specific tasks will include conducting data linkages, contributing to quality improvement activities including machine learning projects, contributing to annual calls-for-data and other deliverables, and contributing to internal and external research and evaluation projects. Other appropriate related duties as assigned.
Minimum Qualifications
Bachelor's degree in Public Health, Epidemiology, Data Science, Biostatistics, or a related field and three years of research experience; OR a Master's degree in a related field and two years of research experience; or a Doctorate in a related field.
Preferred Qualifications
Master's degree in Public Health or a related field. Proficiency in data analysis and interpretation of analysis results. Proficiency using statistical programming and database software such as SAS, R, and SQL. Experience analyzing large public health data files. Experience in cancer surveillance and knowledge of cancer registry standards and operations. Familiarity and experience with machine learning and natural language processing algorithms. Demonstrated excellent oral and written communication skills.
Conditions of Employment
Grant funded position. Compliance with funding requirements such as time and effort reporting, grant deliverables, and contract deliverables, is required.
Visa sponsorship may be available for this position, in accordance with applicable federal requirements.
The selected candidate must reside within a reasonable commuting distance of the official work location specified in the job posting and must also be located in or willing to relocate to one of the following states: New York, New Jersey, Connecticut, Vermont, or Massachusetts, prior to hire.
This position is eligible for a hybrid work schedule, with a combination of onsite and remote work.
HRI participates in the E-Verify Program.
Affirmative Action/Equal Opportunity Employer/Qualified Individuals with Disabilities/Qualified Protected Veterans
**********************
About Health Research, Inc.
Join us in our mission to make a difference in public health and advance scientific research! At Health Research, Inc. (HRI), your work will contribute to meaningful change and innovation in the communities we serve! At HRI, we are on a mission to transform the health and well-being of the people of New York State through innovative partnerships and cutting-edge public health initiatives. As a dynamic non-profit organization, HRI plays a crucial role in advancing the strategic goals of the New York State Department of Health (DOH), Roswell Park Comprehensive Cancer Center (RPCCC), and other health-related entities.
HRI offers a robust, comprehensive benefits package to eligible employees, including:
Health, dental and vision insurance - Several comprehensive health insurance plans to choose from;
Flexible benefit accounts - Medical, dependent care, adoption assistance, parking and transit;
Generous paid time off - Paid federal and state holidays, paid sick, vacation and personal leave;
Tuition support - Assistance is available for individuals pursuing educational or training opportunities;
Retirement Benefits - HRI is a participating employer in the New York State and Local Retirement System and offers optional enrollment in the New York State Deferred Compensation Plan. HRI provides a postretirement Health Benefits Plan for qualified retirees to use towards health insurance premiums and eligible medical expenses;
Employee Assistance Program - Provides educational and wellness programs, training, and 24/7 confidential services to assist employees, both personally and professionally;
And so much more!
$81.7k yearly Auto-Apply 10d ago
Research Scientist ll
Health Research, Inc. 4.5
Menands, NY jobs
Applications to be submitted by January 27, 2026 Compensation Grade: P22 Compensation Details: Minimum: $81,696. 00 - Maximum: $81,696. 00 Annually Positions with a designated work location in New York City, Nassau, Rockland, Suffolk, or Westchester Counties will receive a $4,000 annual downstate adjustment (pro-rated for part-time positions).
Department (OPH) CCH - Division of Chronic Disease Prevention - Bureau of Cancer Epidemiology Job Description: Responsibilities Health Research, Inc.
is seeking a Research Scientist II to work as part of the Bureau of Cancer Epidemiology's analysis and output unit.
The incumbent will be responsible for data analysis using New York State Cancer Registry (NYSCR) data and linked data sources to improve understanding of cancer patterns in NYS.
The incumbent will participate in research and evaluation projects using NYSCR data, including the design, analysis, interpretation, and presentation of findings.
Research and evaluation projects will address multiple aspects of cancer epidemiology including incidence, stage at diagnosis, treatment, survival, and mortality.
The incumbent will also interact with external researchers to provide guidance regarding use of NYSCR data for research and to collaborate on approved projects.
Specific tasks will include conducting data linkages, contributing to quality improvement activities including machine learning projects, contributing to annual calls-for-data and other deliverables, and contributing to internal and external research and evaluation projects.
Other appropriate related duties as assigned.
Minimum Qualifications Bachelor's degree in Public Health, Epidemiology, Data Science, Biostatistics, or a related field and three years of research experience; OR a Master's degree in a related field and two years of research experience; or a Doctorate in a related field.
Preferred Qualifications Master's degree in Public Health or a related field.
Proficiency in data analysis and interpretation of analysis results.
Proficiency using statistical programming and database software such as SAS, R, and SQL.
Experience analyzing large public health data files.
Experience in cancer surveillance and knowledge of cancer registry standards and operations.
Familiarity and experience with machine learning and natural language processing algorithms.
Demonstrated excellent oral and written communication skills.
Conditions of Employment Grant funded position.
Compliance with funding requirements such as time and effort reporting, grant deliverables, and contract deliverables, is required.
Visa sponsorship may be available for this position, in accordance with applicable federal requirements.
The selected candidate must reside within a reasonable commuting distance of the official work location specified in the job posting and must also be located in or willing to relocate to one of the following states: New York, New Jersey, Connecticut, Vermont, or Massachusetts, prior to hire.
This position is eligible for a hybrid work schedule, with a combination of onsite and remote work.
HRI participates in the E-Verify Program.
Affirmative Action/Equal Opportunity Employer/Qualified Individuals with Disabilities/Qualified Protected Veterans www.
healthresearch.
org About Health Research, Inc.
Join us in our mission to make a difference in public health and advance scientific research! At Health Research, Inc.
(HRI), your work will contribute to meaningful change and innovation in the communities we serve! At HRI, we are on a mission to transform the health and well-being of the people of New York State through innovative partnerships and cutting-edge public health initiatives.
As a dynamic non-profit organization, HRI plays a crucial role in advancing the strategic goals of the New York State Department of Health (DOH), Roswell Park Comprehensive Cancer Center (RPCCC), and other health-related entities.
HRI offers a robust, comprehensive benefits package to eligible employees, including: Health, dental and vision insurance - Several comprehensive health insurance plans to choose from; Flexible benefit accounts - Medical, dependent care, adoption assistance, parking and transit; Generous paid time off - Paid federal and state holidays, paid sick, vacation and personal leave; Tuition support - Assistance is available for individuals pursuing educational or training opportunities; Retirement Benefits - HRI is a participating employer in the New York State and Local Retirement System and offers optional enrollment in the New York State Deferred Compensation Plan.
HRI provides a postretirement Health Benefits Plan for qualified retirees to use towards health insurance premiums and eligible medical expenses; Employee Assistance Program - Provides educational and wellness programs, training, and 24/7 confidential services to assist employees, both personally and professionally; And so much more! As the Executive Director of Health Research, Inc.
(HRI), I would like to welcome you to HRI's career page.
HRI's mission is to build a healthier future for New York State and beyond through the delivery of funding and program support to further public health and research programs in support of the New York State Department of Health, Roswell Park Comprehensive Cancer Center and other entities.
This achievement is made possible through the recruitment of highly talented and qualified individuals.
As an Equal Opportunity and Affirmative Action employer, all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, citizenship, age, disability, protected veteran status, or any other characteristic protected by law.
HRI is committed to fostering an environment that encourages collaboration, innovation, and mutual respect and we strive to ensure every individual feels welcomed and appreciated.
We invite you to explore and apply for any open positions that align with your interests.
--- If you are a qualified individual with a disability or a disabled veteran, you may request a reasonable accommodation if you are unable or limited in your ability to access job openings or apply for a job on this site as a result of your disability.
You can request reasonable accommodations by contacting HRI Human Resources at hrihr@healthresearch.
org or **************.
$81.7k yearly Auto-Apply 9d ago
Associate Research Scientist II
Legend Biotech 4.1
Piscataway, NJ jobs
From the very beginning, we have been focusing on the science. We came together as a team of experts, committed to quality, driven by excellence, and dedicated to experimentation. Though we faced many challenges, we remained fearless in our research and rigorous in our thinking, pushing ourselves to work harder. However, what affected us the most was the enormous burden patient's bear and the difficulties they face, which drove us to think about what's next.
We believe it is time to accelerate and expand that transformation. At Legend Biotech, we are excited to bring clinical trials to patients in our pursuit of a cure. While we are focusing on CAR-T in multiple myeloma, we firmly believe the prospects of cellular therapy stretch beyond just one disease or indication. The spark of hope is lit. At Legend Biotech, we are using that hope to ignite the future of CAR-T cell therapy.
Role Overview:
Legend Biotech is a clinical stage biopharmaceutical company focused on the discovery and development of novel cell therapies for oncology, immunology and infectious disease indications. We are currently seeking a talented and motivated candidate to join the R&D cell biology and immunology lab at US site. The successful candidate
will contribute to the company's efforts to develop next-generation cell therapies in solid tumor malignancies. The successful candidate will have a strong Molecular biology/Cell biology and Immunology background, and expect to work in a collaborative cross-functional team environment, perform experiments, organize and analyze results, communicate effectively and present findings in team meetings.
Major Responsibilities:
Assist in developing T cell therapy platform, perform cell-based immunoassays, including ex-vivio antigen specific T cell isolation and expansion, Viral-vector based introduction of TCRs / CARs into human T cells, multi-color flow cytometry, ELISA, ELISPOT assays
Culture and characterize genetically modified human T cells and tumor cells including gene expression and cell functionalities testing
Plan and execute in vitro functional assays with T cells according to project goals and timelines.
Effectively communicate plans and results in both oral and written form.
Ability to work in a highly dynamic collaborative team environment.
Other duties as assigned
Qualifications
Education:
B.S or M.S. in biomedical science field or cell biology and immunology
Experience:
> 5 year with B.S. or 2-5 year with M.S. Industry/academic experience in Immunology/Cell Biology, preferably Immunotherapy.
Key Capabilities, Knowledge, and Skills:
Experience with multi-color flow cytometry and data analysis (FACSDiva, FlowJo) required.
Experience with primary T cell-based assays preferred.
Excellent mammalian cell/tissue culture and sterile technique required.
Strong organizational skills and record keeping.
Self-motivated and willing to accept temporary responsibilities outside of initial job description.
Comfortable in a fast-paced environment and able to adjust workload based upon changing priorities.
Excellent interpersonal, verbal and written communication skills are essential in this collaborative work environment.
Additional Information
Legend Biotech USA Inc. is a proud equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is Legend's policy to ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protected by law.
Legend Biotech USA Inc. maintains a drug-free workplace.
$80k-118k yearly est. 3d ago
Post Doc Fellow
Albany Medical Health System 4.4
Albany, NY jobs
Department/Unit: Neuroscience & Experimental Therapeutic Work Shift: Day (United States of America) Salary Range: $0.00 - $0.00 The Myelin Lab at Albany Medical College, co-led by Drs. Sophie Belin and Yannick Poitelon, is seeking a Postdoctoral Research Fellow to join an NIH-funded project investigating how PMP2, a fatty-acid chaperone, regulates Schwann cell metabolism and the formation and maintenance of peripheral nerve myelin. The work integrates molecular biology, lipid analysis, imaging, and animal models to understand mechanisms underlying peripheral neuropathies.
Albany Medical College offers a focused and highly collaborative biomedical research environment where postdocs work closely with an engaged and approachable faculty.
Postdoctoral fellows also receive robust institutional support through programs such as the Postdoctoral Development Program, which enhances training, career development, and community building both within AMC and across the Capital Region. This support is paired with streamlined access to advanced imaging, histology, and bioinformatics cores, ensuring postdocs have the tools they need to excel.
The Myelin Lab, jointly led by Dr. Yannick Poitelon and Dr. Sophie Belin, provides a supportive dual-PI mentoring environment with expertise in Schwann cell biology, myelination, nerve development, and regeneration. The lab emphasizes rigorous training, hands-on guidance, and scientific independence, supported by active NIH funding and a dynamic research portfolio.
In addition to their main projects, postdocs benefit from opportunities for co-first authorships, strong publication potential, grant-writing support, and individualized career development.
Situated in an affordable, livable, and well-connected region, AMC provides an ideal setting to launch a scientific career, combining high-quality mentorship, cutting-edge resources, and a supportive community.
Key responsibilities
Postdoctoral fellows in the Myelin Lab perform molecular and cell biology techniques, conduct imaging and quantitative analysis of myelin, and work with animal models. They analyze data, prepare figures, and contribute to manuscripts, while also presenting their research at local, national, and international conferences. Fellows participate in the preparation of grants to NIH and foundations under the supervision of Drs. Belin and Poitelon, collaborate closely with both PIs, and assist in mentoring students and research assistants.
Required qualifications
Candidates must have a PhD in Biology, Molecular Biology, Cell Biology, Biochemistry, Genetics, Physiology, Neuroscience, or a related field with a strong hands-on laboratory skills.
They should be able to design experiments, interpret data, and communicate findings clearly. We are seeking candidates that can work both independently and collaboratively in a dynamic research environment.
Strong preference will be given to applicants with:
Experience with Schwann cells, myelin, or peripheral nerve biology. Background knowledge in lipid metabolism, fatty-acid trafficking, or cell metabolic assays. Experience with mouse models or neurobiology techniques.
Thank you for your interest in Albany Medical Center!
Albany Medical is an equal opportunity employer.
This role may require access to information considered sensitive to Albany Medical Center, its patients, affiliates, and partners, including but not limited to HIPAA Protected Health Information and other information regulated by Federal and New York State statutes. Workforce members are expected to ensure that:
Access to information is based on a "need to know" and is the minimum necessary to properly perform assigned duties. Use or disclosure shall not exceed the minimum amount of information needed to accomplish an intended purpose. Reasonable efforts, consistent with Albany Med Center policies and standards, shall be made to ensure that information is adequately protected from unauthorized access and modification.
$46k-57k yearly est. Auto-Apply 37d ago
Scientist, Molecular Profiling
Immunai 4.0
New York, NY jobs
Immunai is an engineering-first platform company aiming to improve therapeutic decision-making throughout the drug discovery and development process. We are mapping the immune system at unprecedented scale and granularity and applying machine learning to this massive clinico-immune database, in order to generate novel insights into disease pathology for our partners - pharma companies and research institutes. We provide a comprehensive, end-to-end solution - from data generation and curation to therapeutics development, that continuously supports and validates the capabilities of our platform.
As drug development is becoming increasingly inefficient, our ultimate goal is to help bring breakthrough medicines to patients as quickly and successfully as possible.
Immunai is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.
About the role:
This position offers an opportunity to work in a highly-collaborative environment with world-leading scientists developing and applying state-of-the art profiling technologies to a diverse set of projects at the intersection of the immune system and disease. The successful candidate will work in a fast-paced team and will interface closely with a multidisciplinary team of immunology, molecular biology, and bioinformatics scientists. Specifically, they will contribute to the Molecular Profiling team performing advanced molecular analyses on a diverse set of clinical and experimental samples. The successful candidate will be an excellent team player, agile in thought, energetic, and willing to learn new methods and skills.
Location: New York City (On-site role)
What will you do?
* Augment efforts of teams using a wide range of techniques including, but not limited to immune cell isolation and processing from human specimens, cell cultures and in vitro model systems
* Domain expert with single cell genomics methods, and proven experience of innovation in this field (sample optimization, protocol development).
* Operation, calibration and maintenance of flow cytometers, cell sorters and related equipment and associated computational hardware
* Maintenance of a complete, accurate, and timely electronic record of all experiments using an informatics management system.
* Active participation in cross-functional team meetings and effective communication with other members of the lab, computational biology, and software team
* Expected to deliver impactful presentations to other colleagues including senior leadership
Requirements
Required qualifications:
* 4-6 years of experience in Molecular Biology or Immunology;
* MS with 2-4 years relevant experience, PhD with 1+ years of post-PhD experience is preferred.
* Experience with protocols for sample and library preparation for single cell multiomics and familiarity with NGS processes. Additionally, familiarity with high-throughput, automated single cell profiling workflows is preferred.
* Experience working with tissue samples, including single cell dissociation.
* Experience with sectioning, staining (immunohistochemistry, fluorescence microscopy, in situ hybridization), imaging and basic image analysis is a distinct advantage
* Familiarity with high throughput lab data management (e.g. Benchling)
* Strong analytical skills, problem solving ability, and innovation aptitude required
* Must be willing to discover and learn new software and technology applications quickly
* Must have strong attention to detail and an ability to multitask
* Ability to collaborate closely with interdisciplinary individuals from a broad range of backgrounds
* Ability to work independently with minimal supervision
* Ability to work successfully in a fast-paced environment
* Excellent interpersonal skills and ability to effectively work as part of a team are essential
* Excellent organization and time management skills
Desired personal traits:
* You want to make an impact on humankind
* You prioritize "We" over "I"
* You enjoy getting things done and striving for excellence
* You collaborate effectively with people of diverse backgrounds and cultures
* You have a growth mindset
* You are candid, authentic, and transparent
Compensation: This position offers a salary typically between $105,000 - $140,000. There is an opportunity to consider higher compensation above this range based on business need, candidate experience, and or skills.
* Please note that when you apply for a position at Immunai, your application will be processed via our recruitment platform SparkHire. You can read more about how we process personal data here: ***************************************
$105k-140k yearly 44d ago
Scientist I (Chester, NY, US, 10918)
Steris Corporation 4.5
Chester, NY jobs
At STERIS, we help our Customers create a healthier and safer world by providing innovative healthcare and life science product and service solutions around the globe. Responsible for the activities related to validation of sterilization processes across STERIS operating facilities. Activities include calibration of data collection systems, such as maintaining dosimeters and dosimetry equipment, measurement of dosimeters for report generation; operation, and data collection related to portable temperature/humidity sensors; coordinating with external laboratories for equipment calibrations and maintenance; coordinating with Customers for test sample processing and requalification studies; coordination and proper handling of product samples for transfer to outside laboratories for testing; and other routine tasks as directed by the immediate supervisor or manager.
What You'll Do as a Scientist I
* Supports the conduct of scientific studies for investigation and validation purposes.
* Contributes to creating and maintaining valid sterilization processes in the medical device or pharmaceutical industry that comply to FDA regulations, ISO, AAMI, and ASTM standards.
* Acts as liaison between Customer and the facility leadership during Customer driven studies.
* Assists in statistical analysis of data, such as variation analysis, specific to the modality in use.
* Contributes to successful product processing by performing dosimeter calibrations or temperature/humidity sensor calibrations.
* Ensures all internal equipment is calibrated per procedure requirements and coordinates calibrations with external vendors.
* Ensures processes are maintained in a validated state by supporting periodic verifications and execution of revalidations or requalifications following changes.
* Contributes to safe and accurate processing by notifying management of any event, item or documentation that may have a concern in regard to regulatory or specification compliance, Customer product quality, or employee safety.
* Maintains a safe work environment by attending safety meetings with local facility, completing safety rounds, and tracking all hazardous materials as contained in the Safety Data Sheets.
* Communicates in an effective manner by utilizing accepted business practices in a courteous and professional manner providing timely and accurate responses and service oriented offers of assistance.
* Protects company confidential information by properly storing, retrieving and disseminating such information only to those authorized.
* Exhibits a commitment to the AST shared values of Customer Satisfaction and Continuous Improvement through ensuring defect-free workmanship, assisting others to meet the Customer's needs, searching for efficient and effective ways to reduce waste, being active and accountable for Customer satisfaction, and satisfying the Customer's needs with a sense of urgency.
* Contributes in a team effort by performing according to the guidelines outlined in the STERIS Code of Business Conduct, the GMP, Lean principles and other directives; supports the directives and decisions of higher level management and performs other duties as assigned.
The Experience, Skills and Abilities Required
Required Qualifications:
* Bachelor's degree in a scientific discipline or related field.
Preferred Qualifications:
* Experience working in a regulated environment (e.g., GMP, GLP, or similar).
* Strong organizational skills with the ability to manage multiple tasks and priorities effectively.
* Demonstrated proactive approach to task management, ensuring timely completion of individual and team objectives.
* Ability to take initiative and maintain accountability for assigned responsibilities.
Pay range for this opportunity is $55,250 to $65,000, dependent on experience and skillset. This position is eligible for bonus participation.
Minimum pay rates offered will comply with county/city minimums, if higher than range listed. Pay rates are based on a number of factors, including but not limited to local labor market costs, years of relevant experience, education, professional certifications, foreign language fluency, etc.
STERIS offers a comprehensive and competitive benefits portfolio. Click here for a complete list of benefits: STERIS Benefits
Open until position is filled.
STERIS is an Equal Opportunity Employer. We are committed to equal employment opportunity to ensure that persons are recruited, hired, trained, transferred and promoted in all job groups regardless of race, color, religion, age, disability, national origin, citizenship status, military or veteran status, sex (including pregnancy, childbirth and related medical conditions), sexual orientation, gender identity, genetic information, and any other category protected by federal, state or local law. We are not only committed to this policy by our status as a federal government contractor, but also we are strongly bound by the principle of equal employment opportunity.
$55.3k-65k yearly 43d ago
Scientist I
Steris 4.5
Chester, NY jobs
At STERIS, we help our Customers create a healthier and safer world by providing innovative healthcare and life science product and service solutions around the globe.
Responsible for the activities related to validation of sterilization processes across STERIS operating facilities. Activities include calibration of data collection systems, such as maintaining dosimeters and dosimetry equipment, measurement of dosimeters for report generation; operation, and data collection related to portable temperature/humidity sensors; coordinating with external laboratories for equipment calibrations and maintenance; coordinating with Customers for test sample processing and requalification studies; coordination and proper handling of product samples for transfer to outside laboratories for testing; and other routine tasks as directed by the immediate supervisor or manager.
What You'll Do as a Scientist I
Supports the conduct of scientific studies for investigation and validation purposes.
Contributes to creating and maintaining valid sterilization processes in the medical device or pharmaceutical industry that comply to FDA regulations, ISO, AAMI, and ASTM standards.
Acts as liaison between Customer and the facility leadership during Customer driven studies.
Assists in statistical analysis of data, such as variation analysis, specific to the modality in use.
Contributes to successful product processing by performing dosimeter calibrations or temperature/humidity sensor calibrations.
Ensures all internal equipment is calibrated per procedure requirements and coordinates calibrations with external vendors.
Ensures processes are maintained in a validated state by supporting periodic verifications and execution of revalidations or requalifications following changes.
Contributes to safe and accurate processing by notifying management of any event, item or documentation that may have a concern in regard to regulatory or specification compliance, Customer product quality, or employee safety.
Maintains a safe work environment by attending safety meetings with local facility, completing safety rounds, and tracking all hazardous materials as contained in the Safety Data Sheets.
Communicates in an effective manner by utilizing accepted business practices in a courteous and professional manner providing timely and accurate responses and service oriented offers of assistance.
Protects company confidential information by properly storing, retrieving and disseminating such information only to those authorized.
Exhibits a commitment to the AST shared values of Customer Satisfaction and Continuous Improvement through ensuring defect-free workmanship, assisting others to meet the Customer's needs, searching for efficient and effective ways to reduce waste, being active and accountable for Customer satisfaction, and satisfying the Customer's needs with a sense of urgency.
Contributes in a team effort by performing according to the guidelines outlined in the STERIS Code of Business Conduct, the GMP, Lean principles and other directives; supports the directives and decisions of higher level management and performs other duties as assigned.
The Experience, Skills and Abilities Required
Required Qualifications:
Bachelor's degree in a scientific discipline or related field.
Preferred Qualifications:
Experience working in a regulated environment (e.g., GMP, GLP, or similar).
Strong organizational skills with the ability to manage multiple tasks and priorities effectively.
Demonstrated proactive approach to task management, ensuring timely completion of individual and team objectives.
Ability to take initiative and maintain accountability for assigned responsibilities.
Pay range for this opportunity is $55,250 to $65,000, dependent on experience and skillset. This position is eligible for bonus participation.
Minimum pay rates offered will comply with county/city minimums, if higher than range listed. Pay rates are based on a number of factors, including but not limited to local labor market costs, years of relevant experience, education, professional certifications, foreign language fluency, etc.
STERIS offers a comprehensive and competitive benefits portfolio. Click here for a complete list of benefits: STERIS Benefits
Open until position is filled.
STERIS is an Equal Opportunity Employer. We are committed to equal employment opportunity to ensure that persons are recruited, hired, trained, transferred and promoted in all job groups regardless of race, color, religion, age, disability, national origin, citizenship status, military or veteran status, sex (including pregnancy, childbirth and related medical conditions), sexual orientation, gender identity, genetic information, and any other category protected by federal, state or local law. We are not only committed to this policy by our status as a federal government contractor, but also we are strongly bound by the principle of equal employment opportunity.
$55.3k-65k yearly 42d ago
Senior Scientist-Bioinformatics
Regeneron Pharmaceuticals 4.9
Tarrytown, NY jobs
The Molecular Profiling and Data Science Department is looking for an enthusiastic and motivated Computational Scientist who values independent research in an open and collaborative working environment. You will participate in original studies that span from basic research to translation studies, directly impacting the lives of patients. You will also have the opportunity to develop novel computational methods from internal and external big data resources. You will join a diverse and inspiring team which cultivates discussion across scientists of differing backgrounds at the exciting intersection of multi-omics, technology development, machine learning, and immuno-oncology. We work closely with biological researchers from different scientific functions, especially the departments of Oncology, Immuno-Oncology, and Early Clinical Development to address critical scientific questions.
In this role, a typical day might include the following:
* Lead computational efforts in the Immuno-Oncology (IO) field by developing or applying cutting-edge methods from bulk RNA sequencing, single cell multi-omics, spatial transcriptomics and other sequencing technologies.
* Work in concert with oncology pre-clinical and clinical teams to design and analyze multi-omics sequencing experiments for target identification, target advancement, biomarker discovery, and clinical profiling
* Prepare clear, concise presentations for collaborators and senior management.
* Publish and present novel findings in peer-reviewed journals and conferences.
* Implement and develop analysis pipelines using cutting-edge algorithms and statistically sound methodologies.
This job might be for you if:
* You are passionate about understanding and utilizing efficient computational techniques to address biological questions.
* Bring innovative thinking to multi-omics data analysis.
* Have a strong work ethic and are proactive in providing solutions to foster scientific collaborations and drive projects forward within Regeneron.
* Can effectively communicate with collaborators of various backgrounds.
* Value teamwork and team excellence.
To be considered for this role, you must:
* Be an enthusiastic and motivated scientist who values independent research in an open and collaborative working environment
* PHD 0-2 years experience
* MS -4+ years experience
Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive culture that provides comprehensive benefits, which vary by location. In the U.S., benefits may include health and wellness programs (including medical, dental, vision, life, and disability insurance), fitness centers, 401(k) company match, family support benefits, equity awards, annual bonuses, paid time off, and paid leaves (e.g., military and parental leave) for eligible employees at all levels! For additional information about Regeneron benefits in the US, please visit ********************************************************************* For other countries' specific benefits, please speak to your recruiter.
Please be advised that at Regeneron, we believe we are most successful and work best when we are together. For that reason, many of Regeneron's roles are required to be performed on-site. Please speak with your recruiter and hiring manager for more information about Regeneron's on-site policy and expectations for your role and your location.
Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business.
For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location.
Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc.
Salary Range (annually)
$93,900.00 - $153,300.00
$93.9k-153.3k yearly Auto-Apply 4d ago
Pharmacovigilance Scientist
Axsome Therapeutics 3.6
Day, NY jobs
Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain's biggest problems so patients and their loved ones can flourish. For more information, please visit us at ************** and follow us on LinkedIn and X.
About This Role
Axsome Therapeutics is seeking a Pharmacovigilance Scientist to establish and execute pharmacovigilance (PV) systems and procedures, with a strong focus on maintaining high-quality standards. This role is responsible for supporting the Pharmacovigilance (PV) Science function under the guidance of the PV physician and providing oversight of ICSR assessment, signal detection, medical surveillance and risk management activities for investigational products in clinical development and marketed products. This position collaborates with key internal stakeholders, including Clinical Development, Commercial, Medical Information, Medical Affairs, Quality, Regulatory and Legal, as well as multiple external Service Providers and partners on pharmacovigilance-related matters.
This position reports to Executive Director of Pharmacovigilance/Drug Safety and is based at Axsome's HQ in New York City with an on-site requirement of at least three days per week. We are unable to consider candidates who are looking for fully remote roles.
Job Responsibilities and Duties include, but are not limited to, the following:
Assist safety physician to enhance safety surveillance and signal detection by monitoring and analyzing safety data from various sources to identify potential safety signals or trends related to investigational and marketed products
Contribute to the creation and execution of risk minimization measures to mitigate identified risks.
Support the preparation pharmacovigilance aggregate safety reports (e.g., PADER, PSURs, DSURs) to regulatory authorities to meet compliance requirements.
Collaborate with PV physician/PV operations and key stakeholders to request/receive applicable sections of the report
Provide training and guidance to other functions to address ad hoc questions and issues
Ensure timely finalization of the reports to meet the submission timelines of relevant health authorities and other external stakeholders
Collaborate and communicate with cross-functional teams to ensure effective safety monitoring and communication
Support the safety review team (SRT) and coordinates all safety topic discussion and documentation.
Ensure appropriate stakeholder representation and input at SRT
Ensure all data is appropriately compiled and presented at SRT for team review
Liaise with SRT chair to facilitate communication and support for decisions resulting from the SRT (e.g. update of RMPs, labeling, regulatory notifications etc.)
Contribute to clinical trials by providing safety input and reviewing documents such as Clinical Study Reports (CSRs), protocols, and investigator brochures (IB), ICF etc.
Provide support for the processing of individual case safety reports (ICSRs) and ensure data accuracy and completeness for investigational and marketed products
Support the PV SOP updates
Oversee vendor safety process, e.g., signal detection, validation and assessment.
Participate in audit/inspection preparedness activities and provide support during regulatory inspections in collaboration with team members
Participate in new study initiation to ensure PV requirements are met including but not limited to safety reporting, query resolution, SAR reconciliation, un-blinding process, and safety reporting training
Evaluate and improve current PV processes, as needed, to strengthen medical surveillance and risk management process ensuring alignment with best practices
Requirements / Qualifications
Master's degree in health-discipline or equivalent required, RN, R.Ph, or Pharm D degree is highly preferred
5+ years of progressively responsible Pharmacovigilance experience in a pharmaceutical, biotechnology, or related environment with focused experience in signal detection, safety surveillance, risk mitigation and risk management
Extensive experience in case processing, regulatory requirements of ICSRs, MedDRA, WHODD, project management
Experience in submission activities in both FDA and EU is preferred, but not required
Must demonstrate the ability to draft reports, business correspondence, and procedures, and to effectively present information and respond to questions from internal and external stakeholders, both domestic and international
Ability to work on site Monday, Tuesday & Thursday. We are unable to consider candidates who are looking for fully remote roles.
Experience and Knowledge
Knowledge of ICH E2B(R2) and (R3) specifications and entry guidance.
Knowledge of global pharmacovigilance reporting rules and timelines, including but not limited to Health Canada, FDA and EMA.
Knowledge of relevant food and drug administration (FDA), European union (EU) and international conference on Harmonization (ICH) guidelines, initiatives, and regulations governing pharmacovigilance.
Ability to interpret health and medical records such as adverse event reporting forms, a discharge summary, etc.
Experience with clinical and/or post-marketing case assessment, including medical terminologies, MedDRA and WHO DD coding and narrative writing.
Experience with safety database is required; ARISg is a plus but not mandatory.
Experience with Veeva is a plus but not mandatory.
Ability to work independently and collaboratively, as required, in a fast-paced matrixed team environment consisting of internal and external team members
Analytical thinker with excellent problem-solving skills and the ability to adapt to changing priorities and deadlines
Ability to read, analyze, and interpret professional journals, technical procedures, and governmental regulations
Excellent planning, organization, and time management skills including the ability to support and prioritize multiple projects
Excellent verbal and written communication and skills
Excellent in detailed-oriented tasks.
Salary & Benefits
The anticipated salary range for this role is $150,000 - $185,000. We encourage candidates of all levels to apply as there may be flexibility on final job title and responsibilities. The salary offer will be based on a variety of factors, including experience, qualifications, internal equity and location. Axsome offers a competitive employment package that includes an annual bonus, significant equity and a generous benefits package.
Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. We value and encourage diversity and solicit applications from all qualified applicants without regard to race, color, gender, sex, age, religion, creed, national origin, sexual orientation, gender identity, ancestry, citizenship, marital status, physical or mental disability, medical condition, veteran status, genetic information, or any other characteristic protected by federal, state, or local law.
Axsome Therapeutics does not accept unsolicited resumes from recruiters or third-party recruitment agencies and will not pay placement fees for unsolicited candidates that are sent to hiring managers, the HR team or other Axsome team members. Only approved vendors who have been explicitly asked to support a specific search will receive access to our Applicant Tracking System to submit candidates for consideration.
$150k-185k yearly Auto-Apply 59d ago
Learn more about Memorial Sloan Kettering Cancer Center jobs