Scientist jobs at Moderna

The Role: Reporting to the Head of the Product Characterization group, the individual in this role will coordinates characterization and comparability studies to support advancement of Moderna's pipeline, including commercial products. The incumbent should be familiar and have hands-on experience with most of the routine biochemical and biophysical characterization techniques used for RNA structural characterization, including mass spectrometry, spectroscopy, calorimetry, liquid chromatography, ELISA, light scattering and next generation sequencing. Demonstrated writing skills are required for protocol drafting and report compilation. Polished communication skills are essential considering that the incumbent will regularly interact with other RAs and Scientists within the Analytical Development, Analytical Technical Operations and Process Development teams. The individual will present scientific findings/results internally or externally. The individual will also evaluate new technologies, optimize methods and write methods SOPs. Here's What You'll Do: Draft testing protocols and compile characterization reports in support of regulatory filings Coordinate sample generation and sample submissions for partner groups Execute testing for various characterization assays including calorimetry, spectroscopy, light scattering and next generation sequencing Perform data analysis and data trending utilizing good documentation practices Record and communicate findings, present results at internal or cross-functional meetings Write/Revise SOPs related to job function Collaborate with other members within the with R&D departments throughout the company Perform general laboratory support activities including equipment maintenance and housekeeping Be accountable for project success and results delivery Here's What You'll Bring to the Table: BS with at least 4 years of industry experience, or MS with at least 2 years of industry experience (Biophysics, Chromatography, Biochemistry, Molecular Biology, or related science), Experience in performing biophysical characterization with focus on mRNA structural characterization Experience with spectroscopy and calorimetry Excellent writing and documentation skills Excellent interpersonal and collaborative skills Ability to work independently and effectively in a highly dynamic environment This position is site-based, requiring you to be at Moderna's site full-time. This position is not eligible for remote work. At Moderna, we are focused on delivering on our mission by enabling talent to thrive. For this role, we are currently unable to offer immigration sponsorship. Candidates must already hold work authorization in US and be able to maintain that status without the need for future sponsorship. Pay & Benefits At Moderna, we believe that when you feel your best, you can do your best work. That's why our US benefits and global well-being resources are designed to support you-at work, at home, and everywhere in between. Best-in-class healthcare coverage, plus voluntary benefit programs to support your unique needs A holistic approach to well-being, with access to fitness, mindfulness, and mental health support Family planning benefits, including fertility, adoption, and surrogacy support Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown Savings and investment opportunities to help you plan for the future Location-specific perks and extras The salary range for this role is $89,900.00 - $143,800.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An individual's position within the salary range will be based on several factors including, but not limited to, specific competencies, relevant education, qualifications, certifications, experience, skills, performance, and business or organizational needs. The successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to company plan eligibility criteria and individual performance. About Moderna Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. Our Working Model As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact. Moderna is a smoke-free, alcohol-free, and drug-free work environment. Equal Opportunities Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply! Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements. Accommodations We're focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best. Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at leavesandaccommodations@modernatx.com. Export Control Notice This position may involve access to technology or data that is subject to U.S. export control laws, including the Export Administration Regulations (EAR). As such, employment is contingent upon the applicant's ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements, only individuals who qualify as U.S. persons (citizens, permanent residents, asylees, or refugees) are eligible for this position. For this role Moderna is unable to sponsor non-U.S. persons to apply for an export control license. #LI-CK1 -

Be a part of the legacy: Postdoctoral Research Fellow Program Our Research Laboratories' Postdoctoral Research Fellow Program aims to be a best-in-industry program for industrial postdoctoral researchers, designed to provide you with an academic focus in a commercial environment. With the resources, reach, and expertise of a large pharmaceutical company, postdoctoral researchers will be positioned to excel in an institution committed to breakthrough innovation in research and discovery. **Postdoctoral Researcher- Integrative Multi-Omics Causal Modeling (Genetics, Genomics)** We are seeking a highly motivated and innovative postdoctoral researcher to join the Data, AI and Genome Sciences (DAGS) department to develop and apply cutting‑edge computational and statistical methods for drug target discovery through multi‑omics integration. The project will develop genetics‑informed causal modeling frameworks by integrating human genetics and genomics data with perturbation‑based sequencing datasets. This unique collaborative role between the Precision Genetics and Genome Sciences groups within DAGS aims to uncover causal gene-pathway-disease relationships, illuminate disease mechanisms, and advance translational research across multiple therapeutic areas. **Key Responsibilities** + Develop scalable and robust statistical and computational methods for causal modeling by integrating human genetics, genomics and perturbation datasets. + Build computational pipelines for genetic association analyses, cell-disease interaction modeling, perturbation-informed pathway and network inference etc. + Apply causal inference and network approaches to infer gene to pathway to phenotype relationships to uncover causal molecular mechanisms. + Continuously track cutting‑edge computational and statistical methods in statistical genetics and computational biology, and proactively propose and pilot innovative ideas and approaches. + Collaborate closely with wet-lab scientists and cross-functional computational teams. + Communicate findings effectively through publications, presentations, and collaborative meetings. **Qualifications** **Required Qualifications** + Candidates must currently hold a Ph.D or Ph.D. completed within 6 months of hire in Statistics, Biostatistics, Computer Science, Mathematics, Statistical Genetics, Computational Biology, Bioinformatics, or a related quantitative field. + Demonstrated experiences analyzing large-scale genomics datasets, such as RNA seq, single cell RNA seq, proteomics etc. + Hands‑on experience applying and/or developing statistical genetics methods such as GWAS, QTL mapping, variant‑set association tests, polygenic scores, and heritability estimation etc. + Proficient programming skills in R and/or Python for data analysis, statistical modeling, and pipeline development. Familiarity with cloud platforms or HPC environments, with experiences on parallel computing and scalable workflow design. + Familiarity with causal inference methods, network/graphical models, or machine‑learning approaches applied to genomics. + Ability to work independently and collaboratively in a multidisciplinary team environment. + Excellent written and oral communication skills, with a demonstrated ability to publish methodological papers or innovative applications in statistical genetics or computational biology. **Preferred Qualifications** + Prior experience with perturbation sequencing assays (CRISPR screens, Perturb‑seq, Drug‑seq) and analysis of perturbation data. + Experiences in integrating multiple omics data types (e.g., genetics, single cell RNA seq etc.) + Experience with Bayesian modeling, graphical models, or causal discovery algorithms. + Experience working with large‑scale biobank (UK Biobank etc.) or consortium datasets and secure research environments (TREs, DNAnexus etc.). postdoctoralopportunities **Required Skills:** Accountability, Accountability, Adaptability, Analytical Chemistry, Bayesian Statistics, Bioinformatics, Biological Sciences, Biostatistics, Cell Culture Techniques, Computational Biology, Computer Science, Data Analysis, Immunoassays, In Vivo Mouse Models, Mathematical Biology, Molecular Biology, Multidisciplinary Collaboration, Parallel Computing, Parasitology, Pipeline Development, Programming Languages, RNA Sequencing, Scientific Research, Scientific Writing, si RNA Knockdown {+ 4 more} **Preferred Skills:** Current Employees apply HERE (***************************************************** Current Contingent Workers apply HERE (***************************************************** **US and Puerto Rico Residents Only:** Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here (*************************************** if you need an accommodation during the application or hiring process. As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit: EEOC Know Your Rights (****************************************************************************************** EEOC GINA Supplement We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively. Learn more about your rights, including under California, Colorado and other US State Acts (********************************************** **U.S. Hybrid Work Model** Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as "remote". **San Francisco Residents Only:** We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance **Los Angeles Residents Only:** We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance **Search Firm Representatives Please Read Carefully** Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. **Employee Status:** Regular **Relocation:** Domestic **VISA Sponsorship:** Yes **Travel Requirements:** 10% **Flexible Work Arrangements:** Not Applicable **Shift:** Not Indicated **Valid Driving License:** No **Hazardous Material(s):** n/a **Job Posting End Date:** 12/6/2025 ***A job posting is effective until 11:59:59PM on the day** **BEFORE** **the listed job posting end date. Please ensure you apply to a job posting no later than the day** **BEFORE** **the job posting end date.** **Requisition ID:** R372225

Be a part of the legacy: Postdoctoral Research Fellow Program Our Research Laboratories' Postdoctoral Research Fellow Program aims to be a best-in-industry program for industrial postdoctoral researchers, designed to provide you with an academic focus in a commercial environment. With the resources, reach, and expertise of a large pharmaceutical company, postdoctoral researchers will be positioned to excel in an institution committed to breakthrough innovation in research and discovery. Postdoctoral Researcher- Integrative Multi-Omics Causal Modeling (Genetics, Genomics) We are seeking a highly motivated and innovative postdoctoral researcher to join the Data, AI and Genome Sciences (DAGS) department to develop and apply cutting‑edge computational and statistical methods for drug target discovery through multi‑omics integration. The project will develop genetics‑informed causal modeling frameworks by integrating human genetics and genomics data with perturbation‑based sequencing datasets. This unique collaborative role between the Precision Genetics and Genome Sciences groups within DAGS aims to uncover causal gene-pathway-disease relationships, illuminate disease mechanisms, and advance translational research across multiple therapeutic areas. Key Responsibilities Develop scalable and robust statistical and computational methods for causal modeling by integrating human genetics, genomics and perturbation datasets. Build computational pipelines for genetic association analyses, cell-disease interaction modeling, perturbation-informed pathway and network inference etc. Apply causal inference and network approaches to infer gene to pathway to phenotype relationships to uncover causal molecular mechanisms. Continuously track cutting‑edge computational and statistical methods in statistical genetics and computational biology, and proactively propose and pilot innovative ideas and approaches. Collaborate closely with wet-lab scientists and cross-functional computational teams. Communicate findings effectively through publications, presentations, and collaborative meetings. QualificationsRequired Qualifications Candidates must currently hold a Ph.D or Ph.D. completed within 6 months of hire in Statistics, Biostatistics, Computer Science, Mathematics, Statistical Genetics, Computational Biology, Bioinformatics, or a related quantitative field. Demonstrated experiences analyzing large-scale genomics datasets, such as RNA seq, single cell RNA seq, proteomics etc. Hands‑on experience applying and/or developing statistical genetics methods such as GWAS, QTL mapping, variant‑set association tests, polygenic scores, and heritability estimation etc. Proficient programming skills in R and/or Python for data analysis, statistical modeling, and pipeline development. Familiarity with cloud platforms or HPC environments, with experiences on parallel computing and scalable workflow design. Familiarity with causal inference methods, network/graphical models, or machine‑learning approaches applied to genomics. Ability to work independently and collaboratively in a multidisciplinary team environment. Excellent written and oral communication skills, with a demonstrated ability to publish methodological papers or innovative applications in statistical genetics or computational biology. Preferred Qualifications Prior experience with perturbation sequencing assays (CRISPR screens, Perturb‑seq, Drug‑seq) and analysis of perturbation data. Experiences in integrating multiple omics data types (e.g., genetics, single cell RNA seq etc.) Experience with Bayesian modeling, graphical models, or causal discovery algorithms. Experience working with large‑scale biobank (UK Biobank etc.) or consortium datasets and secure research environments (TREs, DNAnexus etc.). postdoctoralopportunities Required Skills: Accountability, Accountability, Adaptability, Analytical Chemistry, Bayesian Statistics, Bioinformatics, Biological Sciences, Biostatistics, Cell Culture Techniques, Computational Biology, Computer Science, Data Analysis, Immunoassays, In Vivo Mouse Models, Mathematical Biology, Molecular Biology, Multidisciplinary Collaboration, Parallel Computing, Parasitology, Pipeline Development, Programming Languages, RNA Sequencing, Scientific Research, Scientific Writing, si RNA Knockdown {+ 4 more} Preferred Skills: Current Employees apply HERE Current Contingent Workers apply HERE US and Puerto Rico Residents Only: Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process. As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit: EEOC Know Your Rights EEOC GINA Supplement We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively. Learn more about your rights, including under California, Colorado and other US State Acts U.S. Hybrid Work Model Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”. San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance Search Firm Representatives Please Read Carefully Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. Employee Status: Regular Relocation: Domestic VISA Sponsorship: Yes Travel Requirements: 10% Flexible Work Arrangements: Not Applicable Shift: Not Indicated Valid Driving License: No Hazardous Material(s): n/a Job Posting End Date: 12/6/2025 *A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

**Development of a Cell-Line Agnostic Cell Painting Platform for Drug Discovery.** **Be a part of the legacy: Postdoctoral Research Fellow Program** Our Research Laboratories' Postdoctoral Research Fellow Program aims to be a best-in-industry program for industrial postdoctoral researchers, designed to provide you with an academic focus in a commercial environment. With the resources, reach, and expertise of a large pharmaceutical company, postdoctoral researchers will be positioned to excel in an institution committed to breakthrough innovation in research and discovery. **Position Overview:** We are seeking a Postdoctoral Scientist to join the Quantitative Biosciences (QB) department to develop a flexible, cell line-agnostic morphological profiling platform to characterize perturbations of cell proliferation. The successful candidate will work at the intersection of cell pharmacology, automation and image and data analysis, combining high content imaging techniques with advanced AI/ML to generate unified morphological signatures across multiple cell lines. The postdoctoral research fellow will work in close collaboration with multiple functional areas in our company's network, including Cellular Pharmacology, Oncology and Data Science groups. The platform developed as part of this postdoctoral fellowship aims to translate methods developed for multi-omics integration into a morphological profiling context. The established platform will create a catalog of perturbations, providing a valuable resource for interrogating compound-mediated effects. The data and AI/ML approaches established will potentially have applications beyond the initial project scope. The candidate should have strong laboratory experience, ideally applying high content imaging or quantitative imaging to address biological and/or pharmacological research questions. Additionally, a solid grasp of statistical principles and familiarity with basic machine‑learning or deep‑learning concepts, plus a strong interest in further developing these skills. **Responsibilities include but are not limited to:** The specific responsibilities of the candidate include but are not limited to: + Use automation equipment to perform Cell Painting experiments at scale + Perform data management, preprocessing, and extraction of classical and learned imaging features for downstream analysis. + Develop and apply machine learning and deep-learning approaches to produce cell-line agnostic morphological embeddings and classifiers + Comply with our company's safety and data retention policies, including documenting experimental findings appropriately using an electronic lab notebook + Collaborate closely with Data Science, High Content Imaging, and other Quantitative Biosciences teams. + Prepare scientific reports, presentations, and manuscripts to be shared both internally and externally. **Education Minimum Requirement:** + Candidates must hold a PhD or Ph.D. completed within 6 months of hire in Cell Biology, Molecular Biology, Computational Biology, or a related field. **Required Experience and Skills:** + Hands-on expertise with cell culture and aseptic technique. + Experience with fluorescence microscopy (high content imaging preferred). + Demonstrated experience with quantitative image analysis. + Experience in programming (Python, Matlab, or R) for data analysis and model development. + Basic understanding of machine learning or deep learning methods. + Excellent collaborative and communication skills for cross-disciplinary teamwork and clear reporting. + Excellent organizational skills and a well-developed ability to multi-task effectively and make critical decisions. **Preferred Experience and Skills:** + Prior experience applying high content imaging, using multiple fluorescent markers for multiparametric assessment such as Cell Painting. + Experience with assay automation, medium/high-throughput screening, and plate-based workflows. + Relevant experience with oncology and/or cell proliferation mechanistic studies. + Demonstrated experience building image based ML workflows (preprocessing, cell segmentation, feature extraction or learned embeddings, and model training/validation). + Experience handling and analyzing large imaging datasets; familiarity with data management, metadata capture, and reproducible analysis pipelines. + Familiarity with Python ML libraries (e.g., scikitlearn, PyTorch, TensorFlow) and managing large imaging datasets is desirable. + Experience with cloud‑based computing platforms (e.g., AWS, GCP, or Azure). + Experience integrating imaging data with additional modalities (transcriptomics, proteomics, brightfield) or working with large scale or foundation models for images. + Experience with annotated screening collections or building reference libraries. + Track record of publications and presentations in relevant fields. postdoctoralopportunities **Required Skills:** Accountability, Adaptability, Analytical Chemistry, Cell Culture Techniques, Computational Biology, Data Analysis, Immunoassays, Immunochemistry, Immunology, In Vivo Mouse Models, Mathematical Biology, Molecular Biology, Neurology, Parasitology, Programming Languages, Science, Scientific Research, Scientific Writing, si RNA Knockdown, Statistical Analysis, Synthetic Chemistry **Preferred Skills:** Current Employees apply HERE (***************************************************** Current Contingent Workers apply HERE (***************************************************** **US and Puerto Rico Residents Only:** Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here (*************************************** if you need an accommodation during the application or hiring process. As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit: EEOC Know Your Rights (****************************************************************************************** EEOC GINA Supplement We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively. Learn more about your rights, including under California, Colorado and other US State Acts (********************************************** **U.S. Hybrid Work Model** Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as "remote". **San Francisco Residents Only:** We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance **Los Angeles Residents Only:** We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance **Search Firm Representatives Please Read Carefully** Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. **Employee Status:** Regular **Relocation:** Domestic **VISA Sponsorship:** Yes **Travel Requirements:** 10% **Flexible Work Arrangements:** Not Applicable **Shift:** Not Indicated **Valid Driving License:** No **Hazardous Material(s):** n/a **Job Posting End Date:** 12/6/2025 ***A job posting is effective until 11:59:59PM on the day** **BEFORE** **the listed job posting end date. Please ensure you apply to a job posting no later than the day** **BEFORE** **the job posting end date.** **Requisition ID:** R372551

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at ******************* Job Function: Data Analytics & Computational Sciences Job Sub Function: Data Science Job Category: Scientific/Technology All Job Posting Locations: Cambridge, Massachusetts, United States of America, Spring House, Pennsylvania, United States of America Job Description: Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at *******************/innovative-medicine Johnson & Johnson Innovative Medicine is currently seeking a Principal Scientist, Protein Design, to join our In Silico Protein and Antibody Design team within the Therapeutics Discovery organization, with a preference for this individual to be located at one of our sites in Spring House, PA, or Cambridge, MA. Remote work options within the US may be considered on a case-by-case basis and if approved by the company. This role presents an exciting opportunity to spearhead our molecular design and simulation initiatives, supporting and accelerating our drug discovery and development pipeline of protein-based therapeutics while collaborating with a passionate team of scientists and engineers. Your work will be pivotal in building, evaluating, refining, and applying sophisticated computational approaches and infrastructures. Your efforts will drive the discovery of complex molecules and expedite the development of protein therapeutics across various modalities and indications. Key Responsibilities: You will work closely with colleagues across the organization to design, develop and deliver on differentiated, best in class therapeutic molecules for a range of clinical indications spanning all therapeutic areas. Qualified candidates will have a strong background in computational biology and a proven track record of seeing designs through experimental testing. * Work directly with wet-lab scientists and therapeutic areas to design and optimize protein molecules for specific functions and properties, with a focus on antibody therapeutics. * Collaborate with team members across Therapeutics Discovery on the planning, prioritization, and timely delivery of designs to support multiple concurrent programs * Serve as an In Silico Discovery Lead on diverse project teams * Work with ML colleagues to guide development, benchmarking, and application of pioneering generative and discriminative models. * Model sophisticated biological systems using a variety of methods and tools to advise design methodology. * Participate in internal and external presentations, peer-reviewed manuscripts and conference proceedings Qualifications Education: * PhD in Biomedical Engineering, Biochemistry, Computational Biology, Computer Science, Structural Biology, Biophysics, Material Science, or other related quantitative field with at least 3 years of experience is required. Experience and Skills: * Advanced experience in computational protein modeling, design, structural biology, and biophysics is required * Ability to lead projects in cross-functional teams to completion in a collaborative manner is required * Experience in de novo protein design and sophisticated protein design techniques, such as large-scale backbone editing - for example, fusion design, loop design (inpainting), deletions, and extensions is preferred. * Experience with antibody and/or nanobody modeling and design is preferred. * Experience with high performance computing (on-prem or cloud) is required * Knowledge of critical wet-lab techniques used in protein engineering such as yeast display, SPR, ITC, CD-spectroscopy is preferred. * Solid understanding of current machine learning architectures is preferred. * Advanced proficiency in Python and related data-science packages such as Pandas and Numpy is required. * Excellent communication, reporting and team interaction skills, self-motivated, proactive, and independent. * Experience using Schrodinger, FoldX, Rosetta, Discovery Studio, MOE, GROMACS, NAMD or other molecular dynamics simulation software is preferred * Experience with powerful ML packages for protein modeling and design such as AlphaFold, RosettaFold, ESMFold, ProteinMPNN, RFDiffusion, Chroma, IgFold, DeepAb, Parapred, etc is preferred. * Experience with retraining, fine-tuning, and building ML models such as LLMs to support advanced protein design and protein property prediction tools is preferred. * Experience mentoring and leading junior scientists is strongly preferred. * Desire for continuous learning and the ability to identify, evaluate and deploy emerging algorithms, models, and protein design workflows is required Other: The preference is for this individual to be located at one of our sites in either Spring House, PA, or Cambridge, MA. Remote work options within the US may be considered on a case-by-case basis and if approved by the company. Travel up to 10% may be required. Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via *******************/contact-us/careers , internal employees contact AskGS to be directed to your accommodation resource. The anticipated base pay range for this position is $115,000 to $197,800. The Company maintains highly competitive, performance-based compensation programs. Under current guidelines, this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporation's performance over a calendar/performance year. Bonuses are awarded at the Company's discretion on an individual basis. Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance. Employees may be eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)). Employees are eligible for the following time off benefits: Vacation - up to 120 hours per calendar year Sick time - up to 40 hours per calendar year Holiday pay, including Floating Holidays - up to 13 days per calendar year of Work, Personal and Family Time - up to 40 hours per calendar year Additional information can be found through the link below. ********************************************* The compensation and benefits information set forth in this posting applies to candidates hired in the United States. Candidates hired outside the United States will be eligible for compensation and benefits in accordance with their local market. #LI-SL #JNJDataScience #JNJIMRND-DS #LI-Remote Required Skills: Preferred Skills: Advanced Analytics, Coaching, Critical Thinking, Data Analysis, Data Privacy Standards, Data Quality, Data Reporting, Data Savvy, Data Science, Data Visualization, Digital Fluency, Econometric Models, Organizing, Process Improvements, Strategic Thinking, Technical Credibility, Workflow Analysis

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at ******************* Job Function: Data Analytics & Computational Sciences Job Sub Function: Data Science Job Category: Scientific/Technology All Job Posting Locations: Cambridge, Massachusetts, United States of America, La Jolla, California, United States of America, Spring House, Pennsylvania, United States of America, Titusville, New Jersey, United States of America Job Description: Johnson & Johnson Innovative Medicine is recruiting a Senior Principal Scientist for R&D Data Science and Digital Health, Real-World Evidence Prefered Location: Raritan / Titusville, NJ; Cambridge, MA; or Spring House, PA. May consider remote work. Johnson & Johnson Innovative Medicine develops treatments that improve the health of people worldwide. Research and development areas encompass oncology, cardiovascular and metabolic disorders, immunology, pulmonary hypertension, retinal disorders, and neuroscience. Our goal is to help people live longer, healthier lives. We have produced and marketed many first-in-class prescription medications and are poised to serve the broad needs of the healthcare market - from patients to practitioners and from clinics to hospitals. To learn more about Janssen, one of the Pharmaceutical Companies of Johnson & Johnson, visit ************************************************************ The Data Science Real-World Evidence Analytics & Insights team within Johnson and Johnson Innovative Medicines develops innovative insights and solutions bringing to bear a variety of different data sources across multiple disease areas. We are looking for outstanding scientist and leader whose responsibilities include: * Be a hands-on technical leader, leading a portfolio of RWE projects while instituting best practices, and developing common technical tools, crafting a data-driven culture, of accelerating, scaling and productionalizing deliverables while mentoring and educating peers in the adoption of technical best practices and common tools. * End-to-end expertise in RWE studies including conceptualizing the research questions, data feasibility, study design, analysis, programming, and interpretation. * Provide thought leadership and hand-on programming expertise for developing, adapting and delivering Real-World Data ("RWD") methodologies to mitigate observed and unobserved bias and confounding in the execution of comparative effectiveness analyses, time-to-event analyses, external control arm studies, hybrid control arm studies, retrospective and prospective study designs. * Provide thought leadership and hand-on programming expertise to generating RWE or secondary evidence from post-hoc RCT analyses, observational databases, and literature reviews to support regulatory agency interactions. * Independently create study protocols, statistical analysis plans, and statistical programming deliverables including analysis-ready data, tables, and figures using appropriate statistical analysis software while instituting best practices for execution across the broader team. * Experience creating pipelines, functions, packages to perform frequently used actions and/or deliverables across broad group of stakeholders. * Partner with the Data Science Therapeutic Area scientists to conceptualize, lead, shape and deliver Real World Evidence, and advanced analytics solutions and insights for prioritized use cases taking ownership of one or more disease area evidence generation teams. * Partner closely with R&D DSDH Real-World Evidence LT team to drive strategic and business planning, to take a leading role in facilitating cross-functional operational initiatives, ensuring effective coordination and seamless execution to drive the overall success of Real-World Evidence projects. * Contribute to the development and implementation of best practices, process improvements, and innovative approaches that will further enhance the impact of the Real-World Evidence team. * Contribute to the development and implementation of RW data strategy by identifying and exploring new opportunities for data-driven innovation to support business objectives. * Partner with the Data Science stakeholders to lead and coordinate policy efforts to influence the regulatory acceptability of RWE in decision making. Required qualifications: * A Ph.D. degree, or master's degree in a quantitative field (e.g., epidemiology, statistics, biostatistics, or similar) * At least 5 years of relevant experience within start-up, technology, biopharma or healthcare industries, or highly relevant academic experience, on a case-by-case basis * Extensive hands-on experience with data engineering and exploratory data analysis, statistical modeling, time-to-event analyses, comparative effectiveness analyses, causal inference methods to mitigate observed and residual confounding (e.g., propensity score matching/weighting, instrumental variables, state transition models) * Demonstrated expertise with multiple real-world data sources (EHR, insurance claims, registry data). Familiarity with data structure and programming of clinical trial data * Excellent interpersonal, communication and presentation skills * Extensive experience with database programming and use of statistical programming languages including expert proficiency in either, R or Python working proficiency in SAS and SQL * Demonstrated experience as a technical lead in developing, testing and maintaining technical frameworks for RWE analyses * Extensive knowledge of RWE Common Data Models (OMOP, FHIR, i2b2) & Analysis frameworks (OHDSI, pharmaverse) * Demonstrated experience in managing operations, with strong stakeholder management capabilities. * Demonstrated experience in business planning, resource allocation and prioritization Preferred qualifications: * Familiarity with drug discovery and the clinical development process * Expertise in Oncology, Immunology or Neuroscience drug development * Experience in regulatory-grade evidence, communicating and responding to agency reviews and comments. Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (********************************) or contact AskGS to be directed to your accommodation resource. #LI-GR #LI-Hybrid #JRDDS #JNJDataScience #JRD Required Skills: Preferred Skills: Advanced Analytics, Consulting, Critical Thinking, Data Analysis, Data Privacy Standards, Data Quality, Data Reporting, Data Savvy, Data Science, Data Visualization, Digital Fluency, Econometric Models, Mentorship, Strategic Thinking, Tactical Planning, Technical Credibility The anticipated base pay range for this position is : $137,000 - $235,750 Additional Description for Pay Transparency: Additional Description for Pay Transparency Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance. § Employees may be eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)). § Employees are eligible for the following time off benefits: - Vacation - up to 120 hours per calendar year - Sick time - up to 40 hours per calendar year; for employees who reside in the State of Washington - up to 56 hours per calendar year - Holiday pay, including Floating Holidays - up to 13 days per calendar year - Work, Personal and Family Time - up to 40 hours per calendar year Additional information can be found through the link below.

Career CategoryResearchJob DescriptionJoin Amgen's Mission of Serving Patients At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do. Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas -Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Senior Scientist - Research Computational Biology (ARIA) What you will do Let's do this. The ARIA Computational Biology team is seeking a talented and creative computational biologist to further our mission of serving patients by advancing and replenishing the Amgen therapeutic pipeline. In this role you will apply your expertise in data science and disease biology to accelerate the identification, prioritization, and validation of transformative therapeutic targets in a dynamic cross-functional research environment. Focus areas include: Extracting biological insight from complex multi-modal omics and screening data to characterize disease endotypes and mechanisms, identify novel targets and biomarkers, and test therapeutic hypotheses. Developing and leveraging methods/platforms to discover, prioritize, and validate targets across diverse diseases and therapeutic modalities Innovative research in close partnership with Amgen therapeutic area scientists, spanning both internal pipeline programs and external partnerships. Partnering with our data science and information systems teams to incorporate tools and analyses developed within ARIA Computational Biology into integrated R&D platforms. What we expect of you We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a computational biologist with these qualifications. Basic Qualifications: Doctorate in computational biology, bioinformatics, data science, or a related discipline [and relevant post-doc where applicable] Or Master's degree and 3 years of relevant research experience Or Bachelor's degree and 5 years of relevant research experience Preferred Qualifications: Strong programming skills (Python, R, Linux/Unix), familiarity with cloud computing environments, HPC, and collaborative coding practices (e.g., Git). Track record of designing and implementing creative and holistic computational strategies to address challenging research questions. Demonstrated expertise in the analysis and interpretation of single cell omics data. Excellent presentation and communication skills to convey complex findings to diverse audiences. Self-starter with a collaborative mentality and a drive for continuous growth. Strong background in cardiometabolic disease and/or immunology, including application to the interpretation of single-cell data. Experience leveraging and fine-tuning transcriptional foundation models, LLMs, and biomedical knowledge graphs to further research goals. Familiarity with public data resources (e.g. DepMap, Human Cell Atlas, TCGA, GTEx, and Tahoe-100M) frequently used to augment analyses of internally generated data. Experience developing and deploying tools and pipelines to endpoints such as interactive portals (e.g. RShiny apps), workflow management systems (e.g Nextflow), and agentic frameworks. What you can expect from us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we'll support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans Flexible work models, including remote and hybrid work arrangements, where possible Apply now and make a lasting impact with the Amgen team. careers.amgen.com In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. . Salary Range 132,494.00 USD - 163,875.00 USD

The Role is located in Norwood, MA and has a start date of August 3, 2026. The Technical Development organization at Moderna is looking for top talent in science and engineering to deliver on its mission to design manufacturing processes for mRNA medicines. This posting is for a full-time position in Moderna's Technical Development Rotation Program. Rotation Program participants will have an exciting opportunity to explore different areas of mRNA therapeutic development through completing three 6-month rotations in Technical Development. Participants will be part of high-performing project teams developing new manufacturing platforms to produce mRNA therapeutics and vaccines destined for clinical trials and commercial licensure. You will apply your educational background and learn new technical skills in the synthesis of mRNA, assembly of lipid nanoparticles, and formulation of drug products. Through completing an operational rotation, you will develop a deep understanding of how Technical Development's efforts enable the manufacture of mRNA medicines. Technical Development is based in Norwood, MA. Here's What You'll Do Work with a team of highly skilled experts to come up to speed on technology and techniques. Use laboratory, technical and communication skills to generate experimental results, perform data analysis, and document in formal reports including conclusions and recommended next steps. Perform process scale-up, support technology transfer and provide manufacturing support at internal Moderna, and external contract manufacturing sites. Participate in planning, design, execution, analysis of experiments and formal risk assessments to establish critical process parameters, and overall process control strategies. Optimize the impact of formulation and processing conditions on the stability of mRNA drug products and process intermediates. Review and share relevant academic literature and establish new collaborations with internal research and manufacturing groups. Create scaled-down models, and high throughput experimental setups for unit operations. Characterize mRNA and lipid nanoparticles through collaboration with the analytical team. Prepare technical reports and present finding in cross-functional meetings. Additional duties as may be assigned from time to time. Here's What You'll Need (Basic Qualifications) Bachelors or Masters Degree in Chemical Engineering, Biochemical Engineering, Bioengineering, Biomolecular Engineering, Chemistry, Biochemistry, Biomedical Engineering, Biophysics, Biostatistics, Biotechnology, Mathematics, Molecular Biology, Pharmaceutical Science, Statistics, or a related field preferred. Strong fundamental scientific and engineering skills for the evaluation of experimental data Laboratory skills applicable to bioprocess development and analytical methods At Moderna, we are focused on delivering on our mission by enabling talent to thrive. For this role, we are currently unable to offer immigration sponsorship. Candidates must already hold work authorization in US and be able to maintain that status without the need for future sponsorship. This position is site-based, requiring you to be at Moderna's site full-time. This position is not eligible for remote work. Here's What You'll Bring to the Table (Preferred Qualifications) GPA of 3.5 on a 4 scale or equivalent Demonstrated ability to work both independently as well as the ability to contribute to high performing teams. Excellent written and verbal communication skills. Demonstrated aptitude or ability to learn in order to gain a strong understanding of GxP regulations (GxP, GMP, GLP) A desire to make an impact as part of a high-growth, transformational company that is Bold, Relentless, Curious, and Collaborative. Pay & Benefits At Moderna, we believe that when you feel your best, you can do your best work. That's why our US benefits and global well-being resources are designed to support you-at work, at home, and everywhere in between. Best-in-class healthcare coverage, plus voluntary benefit programs to support your unique needs A holistic approach to well-being, with access to fitness, mindfulness, and mental health support Family planning benefits, including fertility, adoption, and surrogacy support Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown Savings and investment opportunities to help you plan for the future Location-specific perks and extras The salary range for this role is $63,200.00 - $100,900.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An individual's position within the salary range will be based on several factors including, but not limited to, specific competencies, relevant education, qualifications, certifications, experience, skills, performance, and business or organizational needs. The successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to company plan eligibility criteria and individual performance. About Moderna Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. Our Working Model As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact. Moderna is a smoke-free, alcohol-free, and drug-free work environment. Equal Opportunities Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply! Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements. Accommodations We're focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best. Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at leavesandaccommodations@modernatx.com. Export Control Notice This position may involve access to technology or data that is subject to U.S. export control laws, including the Export Administration Regulations (EAR). As such, employment is contingent upon the applicant's ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements, only individuals who qualify as U.S. persons (citizens, permanent residents, asylees, or refugees) are eligible for this position. For this role Moderna is unable to sponsor non-U.S. persons to apply for an export control license. -

Development of a Cell-Line Agnostic Cell Painting Platform for Drug Discovery. Be a part of the legacy: Postdoctoral Research Fellow Program Our Research Laboratories' Postdoctoral Research Fellow Program aims to be a best-in-industry program for industrial postdoctoral researchers, designed to provide you with an academic focus in a commercial environment. With the resources, reach, and expertise of a large pharmaceutical company, postdoctoral researchers will be positioned to excel in an institution committed to breakthrough innovation in research and discovery. Position Overview: We are seeking a Postdoctoral Scientist to join the Quantitative Biosciences (QB) department to develop a flexible, cell line-agnostic morphological profiling platform to characterize perturbations of cell proliferation. The successful candidate will work at the intersection of cell pharmacology, automation and image and data analysis, combining high content imaging techniques with advanced AI/ML to generate unified morphological signatures across multiple cell lines. The postdoctoral research fellow will work in close collaboration with multiple functional areas in our company's network, including Cellular Pharmacology, Oncology and Data Science groups. The platform developed as part of this postdoctoral fellowship aims to translate methods developed for multi-omics integration into a morphological profiling context. The established platform will create a catalog of perturbations, providing a valuable resource for interrogating compound-mediated effects. The data and AI/ML approaches established will potentially have applications beyond the initial project scope. The candidate should have strong laboratory experience, ideally applying high content imaging or quantitative imaging to address biological and/or pharmacological research questions. Additionally, a solid grasp of statistical principles and familiarity with basic machine‑learning or deep‑learning concepts, plus a strong interest in further developing these skills. Responsibilities include but are not limited to: The specific responsibilities of the candidate include but are not limited to: Use automation equipment to perform Cell Painting experiments at scale Perform data management, preprocessing, and extraction of classical and learned imaging features for downstream analysis. Develop and apply machine learning and deep-learning approaches to produce cell-line agnostic morphological embeddings and classifiers Comply with our company's safety and data retention policies, including documenting experimental findings appropriately using an electronic lab notebook Collaborate closely with Data Science, High Content Imaging, and other Quantitative Biosciences teams. Prepare scientific reports, presentations, and manuscripts to be shared both internally and externally. Education Minimum Requirement: Candidates must hold a PhD or Ph.D. completed within 6 months of hire in Cell Biology, Molecular Biology, Computational Biology, or a related field. Required Experience and Skills: Hands-on expertise with cell culture and aseptic technique. Experience with fluorescence microscopy (high content imaging preferred). Demonstrated experience with quantitative image analysis. Experience in programming (Python, Matlab, or R) for data analysis and model development. Basic understanding of machine learning or deep learning methods. Excellent collaborative and communication skills for cross-disciplinary teamwork and clear reporting. Excellent organizational skills and a well-developed ability to multi-task effectively and make critical decisions. Preferred Experience and Skills: Prior experience applying high content imaging, using multiple fluorescent markers for multiparametric assessment such as Cell Painting. Experience with assay automation, medium/high-throughput screening, and plate-based workflows. Relevant experience with oncology and/or cell proliferation mechanistic studies. Demonstrated experience building image based ML workflows (preprocessing, cell segmentation, feature extraction or learned embeddings, and model training/validation). Experience handling and analyzing large imaging datasets; familiarity with data management, metadata capture, and reproducible analysis pipelines. Familiarity with Python ML libraries (e.g., scikitlearn, PyTorch, TensorFlow) and managing large imaging datasets is desirable. Experience with cloud‑based computing platforms (e.g., AWS, GCP, or Azure). Experience integrating imaging data with additional modalities (transcriptomics, proteomics, brightfield) or working with large scale or foundation models for images. Experience with annotated screening collections or building reference libraries. Track record of publications and presentations in relevant fields. postdoctoralopportunities Required Skills: Accountability, Adaptability, Analytical Chemistry, Cell Culture Techniques, Computational Biology, Data Analysis, Immunoassays, Immunochemistry, Immunology, In Vivo Mouse Models, Mathematical Biology, Molecular Biology, Neurology, Parasitology, Programming Languages, Science, Scientific Research, Scientific Writing, si RNA Knockdown, Statistical Analysis, Synthetic Chemistry Preferred Skills: Current Employees apply HERE Current Contingent Workers apply HERE US and Puerto Rico Residents Only: Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process. As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit: EEOC Know Your Rights EEOC GINA Supplement We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively. Learn more about your rights, including under California, Colorado and other US State Acts U.S. Hybrid Work Model Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”. San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance Search Firm Representatives Please Read Carefully Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. Employee Status: Regular Relocation: Domestic VISA Sponsorship: Yes Travel Requirements: 10% Flexible Work Arrangements: Not Applicable Shift: Not Indicated Valid Driving License: No Hazardous Material(s): n/a Job Posting End Date: 12/6/2025 *A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Career CategoryOperationsJob DescriptionJoin Amgen's Mission of Serving Patients At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do. Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas -Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Process Development Sr. Associate - Drug Product Technology What you will do Let's do this. Let's change the world. In this vital role you will join the Pre-Pivotal Drug Product, Synthetics Enabling Technologies (SET) team and support the characterization and development of small molecule drug candidates. This role is primarily laboratory-based and focuses on understanding physicochemical and biopharmaceutical properties that impact formulation design, stability, and oral bioavailability. The candidate will work closely with scientists on molecule assessment, solid-state characterization, and analytical teams to support early development programs. Key Responsibilities include: Conduct physicochemical profiling of small molecule drug candidates (e.g., solubility, pKa, logP/logD, hygroscopicity, dissolution, and chemical stability). Assess developability risks by integrating experimental data on molecular properties. Support material characterization to guide form selection and formulation strategy. Perform solid-state analysis including X-ray powder diffraction (XRPD), differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), FT-IR, Raman spectroscopy, and solid-state NMR (as applicable). Execute manual and automated high-throughput screening workflows. Prepare and characterize preclinical formulations (solutions, suspensions, solid dispersions, etc.) to enable in vivo studies. Maintain accurate, detailed experimental records in electronic laboratory notebooks (ELN). Document and interpret data to support regulatory filings and internal reports. What we expect of you We are all different, yet we all use our unique contributions to serve patients. The scientific professional we seek is a collaborative individual with these qualifications. Basic Qualifications: High school diploma / GED and 6 years of Scientific experience OR Associate's degree and 4 years of Scientific experience OR Bachelor's degree and 2 years of Scientific experience OR Master's degree Preferred Qualifications: B.S. in Chemistry, Chemical Engineering, Materials Science, Pharmaceutical Science, or a related scientific field, with at least two years of pharmaceutical/biotech industry experience. Hands-on experience with solid-state and preformulation techniques. Familiarity with data interpretation from XRPD, DSC, TGA, and spectroscopic methods. Experience with high-throughput screening or automated liquid handling is desirable. Strong attention to detail and commitment to data quality. Effective communication and teamwork skills. What you can expect of us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we'll support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans Flexible work models, including remote and hybrid work arrangements, where possible Apply now and make a lasting impact with the Amgen team.careers.amgen.com In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. . Salary Range 85,306.00 USD - 103,484.00 USD

Career CategoryScientificJob Description Join Amgen's Mission of Serving Patients At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do. Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas -Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Process Development Senior Scientist - Attribute Sciences What you will do Let's do this! Let's change the world! This is an exciting opportunity to join the Amgen Biologics Pivotal Attribute Sciences team based in Cambridge, Massachusetts. In this role you will: Architect and deploy end-to-end assay automation including sample prep, instrument integration, data processing, and report generation to reduce hands-on time and increase lab efficiency. Develop, qualify/validate, and transfer protein analytical methods (e.g., CE-SDS, IEX, SEC, LC-MS), leveraging automation to improve throughput, reproducibility, and data integrity. Lead training, qualification, and transfer from our process development labs to our global quality network partners. Interpret analytical results, author and review technical protocols/reports, and contribute to analytical CMC sections in regulatory filing documents including IND and BLAs. Serve as analytical subject matter expert supporting characterization studies, data analysis, and investigations while interfacing and collaborating with our functional partners in a matrix environment. Design and execute late‑stage process/product characterization and forced‑degradation studies utilizing protein chemistry, separation sciences, mass spectrometry, and lab automation. Drive automation-enabled innovation in Process Development by standardizing methods and applying DoE to reduce assay cycle time and raise first-pass transfer rates. What we expect of you We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is an individual with these qualifications. Basic Qualifications: Bachelor's degree and 5 years of Scientific experience OR Master's degree and 3 years of Scientific experience OR Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable] Preferred Qualifications: Strong written and verbal communication skills, ability to interact effectively with diverse internal and external stakeholders 5+ years of experience in industrial analytical laboratories supporting characterization of protein therapeutics, including experience coordinating with QC laboratories to execute method transfers, validations and troubleshooting In-depth expertise in multiple analytical techniques (i.e., SE-HPLC, IEX, CE-SDS, LC-MS); characterization of protein modifications Expertise with laboratory automation including liquid handlers, pipetting robots, and automation software Experience in method transfers, method validation, method troubleshooting, and complex investigations Familiarity with and understanding of United States Pharmacopeia (USP), International Conference on Harmonization (ICH), and Food & Drug Administration (FDA) guidance documents related to analytical method transfer and validation Experience in authoring and reviewing regulatory submissions, especially module 3 (Quality) common technical documents for IND/BLA submissions Proficiency in solving complex problems; ability to work independently, proactively seek outside resources and collaboration, effectively plan and follow through on complex projects What you can expect from us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we'll support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans Flexible work models, including remote and hybrid work arrangements, where possible Apply now and make a lasting impact with the Amgen team. careers.amgen.com In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Sponsorship Sponsorship for this role is not guaranteed. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. . Salary Range 127,764.00 USD - 152,656.00 USD

Career CategoryScientificJob Description Join Amgen's Mission of Serving Patients At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do. Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas -Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Process Development Principal Scientist What you will do Let's do this! Let's change the world! In this pivotal role within Amgen's Commercial Drug Product Technologies group, you will be responsible for process development and lifecycle management of commercial drug product formulation and fill/finish processes across various modalities. You will provide technical and project leadership while integrating information generated by cross functional teams to ensure success through the commercialization and life-cycle of the products. Role Responsibilities: Serve as a leader on Drug Product Commercialization Teams responsible for planning, designing, executing, and documenting laboratory studies related to drug product design, formulation, and process development in support of commercialization and lifecycle management of both parenteral and oral solid dosage presentations Provide support, as needed, to clinical and commercial fill/finish manufacturing operations through process capability analysis, troubleshooting, root cause analysis, and product impact assessments for non-conformance investigations and process changes/improvements. Drive continuous improvement in the drug product development process through technological innovation and application of first principles in process engineering. Participate and lead global cross-functional teams working effectively in a highly matrixed team environment to influence and inspire change, efficiency, and cultivate strong relationships. Author and review guideline documents, technical protocols, reports, product impact assessments, regulatory submissions, and developing responses to regulatory questions. Deliver progress reports and presentations to ensure management awareness and engagement of the status, progress, and future program and functional needs. Actively utilize advanced IS systems to improve drug product design through faster data availability, using historical information, analyzing large data sets, and statistical analysis. Ability to travel domestically and internationally up to 10% of the time. What we expect of you We are all different, yet we all use our unique contributions to serve patients. The scientific professional we seek is a collaborative leader with these qualifications. Basic Qualifications: Bachelor's degree and 7 years of Scientific experience OR Master's degree and 5 years of Scientific experience OR Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable] and 2 years of Scientific experience Preferred Qualifications: Advanced degree in Pharmaceutics, Biotechnology, Engineering, Material Science or related subject area 5+ years of post-doctoral or industry experience in pharmaceuticals/biotechnology or related field Knowledge of/hands-on experience with end-to-end development for liquid, lyophilized and/or oral solid dosage drug products in various presentations Knowledge and awareness of the regulations governing combination product development Experience with parenteral biologics (i.e. filling, filtration, mixing, etc.) process characterization, scale-up, and commercial manufacturing Understanding of physical/chemical stability of proteins and how process related stress impacts product quality, specifically, the impact of freezing and drying to short- and long-term stability Aseptic processing experience and familiarity with cGMPs, ICH guidelines, and pre-approval inspection/audits Experience that includes elements of new product development, process characterization, equipment design and implementation, technical transfers to global manufacturing sites, statistical process control (SPC), and statistical design and analysis of experiments Strong problem solving and effective interpersonal skills, and the ability to influence colleagues with ideas. Previous scientific and managerial experience in support of drug product development, investigations, and regulatory filings is important. Ability to learn and rapidly react in an environment with dynamic information. What you can expect from us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we'll support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans Flexible work models, including remote and hybrid work arrangements, where possible Apply now and make a lasting impact with the Amgen team. careers.amgen.com In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Sponsorship Sponsorship for this role is not guaranteed. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. . Salary Range 148,363.00 USD - 171,657.00 USD

Join Amgen's Mission of Serving Patients At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do. Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas -Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Process Development Senior Scientist - Attribute Sciences What you will do Let's do this! Let's change the world! This is an exciting opportunity to join the Amgen Biologics Pivotal Attribute Sciences team based in Cambridge, Massachusetts. In this role you will: * Architect and deploy end-to-end assay automation including sample prep, instrument integration, data processing, and report generation to reduce hands-on time and increase lab efficiency. * Develop, qualify/validate, and transfer protein analytical methods (e.g., CE-SDS, IEX, SEC, LC-MS), leveraging automation to improve throughput, reproducibility, and data integrity. * Lead training, qualification, and transfer from our process development labs to our global quality network partners. * Interpret analytical results, author and review technical protocols/reports, and contribute to analytical CMC sections in regulatory filing documents including IND and BLAs. * Serve as analytical subject matter expert supporting characterization studies, data analysis, and investigations while interfacing and collaborating with our functional partners in a matrix environment. * Design and execute late‑stage process/product characterization and forced‑degradation studies utilizing protein chemistry, separation sciences, mass spectrometry, and lab automation. * Drive automation-enabled innovation in Process Development by standardizing methods and applying DoE to reduce assay cycle time and raise first-pass transfer rates. What we expect of you We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is an individual with these qualifications. Basic Qualifications: * Bachelor's degree and 5 years of Scientific experience OR * Master's degree and 3 years of Scientific experience OR * Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable] Preferred Qualifications: * Strong written and verbal communication skills, ability to interact effectively with diverse internal and external stakeholders * 5+ years of experience in industrial analytical laboratories supporting characterization of protein therapeutics, including experience coordinating with QC laboratories to execute method transfers, validations and troubleshooting * In-depth expertise in multiple analytical techniques (i.e., SE-HPLC, IEX, CE-SDS, LC-MS); characterization of protein modifications * Expertise with laboratory automation including liquid handlers, pipetting robots, and automation software * Experience in method transfers, method validation, method troubleshooting, and complex investigations * Familiarity with and understanding of United States Pharmacopeia (USP), International Conference on Harmonization (ICH), and Food & Drug Administration (FDA) guidance documents related to analytical method transfer and validation * Experience in authoring and reviewing regulatory submissions, especially module 3 (Quality) common technical documents for IND/BLA submissions * Proficiency in solving complex problems; ability to work independently, proactively seek outside resources and collaboration, effectively plan and follow through on complex projects What you can expect from us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we'll support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: * A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts * A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan * Stock-based long-term incentives * Award-winning time-off plans * Flexible work models, including remote and hybrid work arrangements, where possible Apply now and make a lasting impact with the Amgen team. careers.amgen.com In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Sponsorship Sponsorship for this role is not guaranteed. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. . Salary Range 127,764.00 USD - 152,656.00 USD

**Join Amgen's Mission of Serving Patients** At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do. Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas -Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. **Process Development Principal** Scientist **What you will do** Let's do this! Let's change the world! In this pivotal role within Amgen's Commercial Drug Product Technologies group, you will be responsible for process development and lifecycle management of commercial drug product formulation and fill/finish processes across various modalities. You will provide technical and project leadership while integrating information generated by cross functional teams to ensure success through the commercialization and life-cycle of the products. **Role Responsibilities:** + Serve as a leader on Drug Product Commercialization Teams responsible for planning, designing, executing, and documenting laboratory studies related to drug product design, formulation, and process development in support of commercialization and lifecycle management of both parenteral and oral solid dosage presentations + Provide support, as needed, to clinical and commercial fill/finish manufacturing operations through process capability analysis, troubleshooting, root cause analysis, and product impact assessments for non-conformance investigations and process changes/improvements. + Drive continuous improvement in the drug product development process through technological innovation and application of first principles in process engineering. + Participate and lead global cross-functional teams working effectively in a highly matrixed team environment to influence and inspire change, efficiency, and cultivate strong relationships. + Author and review guideline documents, technical protocols, reports, product impact assessments, regulatory submissions, and developing responses to regulatory questions. + Deliver progress reports and presentations to ensure management awareness and engagement of the status, progress, and future program and functional needs. + Actively utilize advanced IS systems to improve drug product design through faster data availability, using historical information, analyzing large data sets, and statistical analysis. + Ability to travel domestically and internationally up to 10% of the time. **What we expect of you** We are all different, yet we all use our unique contributions to serve patients. The scientific professional we seek is a collaborative leader with these qualifications. **Basic Qualifications:** + Bachelor's degree and 7 years of Scientific experience OR + Master's degree and 5 years of Scientific experience OR + Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable] and 2 years of Scientific experience **Preferred Qualifications:** + Advanced degree in Pharmaceutics, Biotechnology, Engineering, Material Science or related subject area + 5+ years of post-doctoral or industry experience in pharmaceuticals/biotechnology or related field + Knowledge of/hands-on experience with end-to-end development for liquid, lyophilized and/or oral solid dosage drug products in various presentations + Knowledge and awareness of the regulations governing combination product development + Experience with parenteral biologics (i.e. filling, filtration, mixing, etc.) process characterization, scale-up, and commercial manufacturing + Understanding of physical/chemical stability of proteins and how process related stress impacts product quality, specifically, the impact of freezing and drying to short- and long-term stability + Aseptic processing experience and familiarity with cGMPs, ICH guidelines, and pre-approval inspection/audits + Experience that includes elements of new product development, process characterization, equipment design and implementation, technical transfers to global manufacturing sites, statistical process control (SPC), and statistical design and analysis of experiments + Strong problem solving and effective interpersonal skills, and the ability to influence colleagues with ideas. + Previous scientific and managerial experience in support of drug product development, investigations, and regulatory filings is important. + Ability to learn and rapidly react in an environment with dynamic information. **What you can expect from us** As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we'll support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: + A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts + A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan + Stock-based long-term incentives + Award-winning time-off plans + Flexible work models, including remote and hybrid work arrangements, where possible **Apply now and make a lasting impact with the Amgen team.** **careers.amgen.com** In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. **Sponsorship** Sponsorship for this role is not guaranteed. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

**Join Amgen's Mission of Serving Patients** At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do. Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas -Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. **Process Development Senior Scientist - Attribute Sciences** **What you will do** Let's do this! Let's change the world! This is an exciting opportunity to join the Amgen Biologics Pivotal Attribute Sciences team based in Cambridge, Massachusetts. In this role you will: + Architect and deploy end-to-end assay automation including sample prep, instrument integration, data processing, and report generation to reduce hands-on time and increase lab efficiency. + Develop, qualify/validate, and transfer protein analytical methods (e.g., CE-SDS, IEX, SEC, LC-MS), leveraging automation to improve throughput, reproducibility, and data integrity. + Lead training, qualification, and transfer from our process development labs to our global quality network partners. + Interpret analytical results, author and review technical protocols/reports, and contribute to analytical CMC sections in regulatory filing documents including IND and BLAs. + Serve as analytical subject matter expert supporting characterization studies, data analysis, and investigations while interfacing and collaborating with our functional partners in a matrix environment. + Design and execute late‑stage process/product characterization and forced‑degradation studies utilizing protein chemistry, separation sciences, mass spectrometry, and lab automation. + Drive automation-enabled innovation in Process Development by standardizing methods and applying DoE to reduce assay cycle time and raise first-pass transfer rates. **What we expect of you** We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is an individual with these qualifications. **Basic Qualifications:** + Bachelor's degree and 5 years of Scientific experience OR + Master's degree and 3 years of Scientific experience OR + Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable] **Preferred Qualifications:** + Strong written and verbal communication skills, ability to interact effectively with diverse internal and external stakeholders + 5+ years of experience in industrial analytical laboratories supporting characterization of protein therapeutics, including experience coordinating with QC laboratories to execute method transfers, validations and troubleshooting + In-depth expertise in multiple analytical techniques (i.e., SE-HPLC, IEX, CE-SDS, LC-MS); characterization of protein modifications + Expertise with laboratory automation including liquid handlers, pipetting robots, and automation software + Experience in method transfers, method validation, method troubleshooting, and complex investigations + Familiarity with and understanding of United States Pharmacopeia (USP), International Conference on Harmonization (ICH), and Food & Drug Administration (FDA) guidance documents related to analytical method transfer and validation + Experience in authoring and reviewing regulatory submissions, especially module 3 (Quality) common technical documents for IND/BLA submissions + Proficiency in solving complex problems; ability to work independently, proactively seek outside resources and collaboration, effectively plan and follow through on complex projects **What you can expect from us** As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we'll support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: + A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts + A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan + Stock-based long-term incentives + Award-winning time-off plans + Flexible work models, including remote and hybrid work arrangements, where possible **Apply now and make a lasting impact with the Amgen team.** **careers.amgen.com** In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. **Sponsorship** Sponsorship for this role is not guaranteed. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at ******************* Job Function: Data Analytics & Computational Sciences Job Sub Function: Data Science Job Category: Scientific/Technology All Job Posting Locations: Cambridge, Massachusetts, United States of America, San Diego, California, United States of America, Spring House, Pennsylvania, United States of America Job Description: Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at *******************/innovative-medicine Johnson & Johnson Innovative Medicine is hiring a Principal Scientist, Cheminformatics to join our team. The US location options for this position are Spring House, PA, Cambridge, MA, and San Diego, CA. Consideration may also be given for this position to be located in Beerse, Belgium. Please note that this role is available across multiple countries and may be posted under different requisition numbers to comply with local requirements. While you are welcome to apply to any or all of the postings, we recommend focusing on the specific country that aligns with your preferred location: USA - Requisition Number: R-026889 Belgium - Requisition Number: R-027978 We are seeking a highly skilled and innovative Principal Scientist in Cheminformatics to join our team. While strong emphasis will be put on informatics support for our DNA Encoded Library (DEL) platform, the successful candidate will also play a broader role in establishing industry-leading small molecule informatics capabilities, supporting bench scientists in every step of the DMTA cycle and guiding them in analysis and decision-making. This role will collaborate closely with project and platform teams to understand their ways of working and participate in the development of a future-looking informatics strategy for small molecules, including data provisioning, analytics, and visualization for hit identification and compound optimization. Key Responsibilities: * Lead the development and implementation of advanced cheminformatics tools for small molecule analysis and DEL informatics. * Implement statistical approaches to improve selection of compounds for off-DNA synthesis and accelerate workups of DEL screens. * Enhance our internal DEL ML virtual screening capabilities and apply to key projects. * Collaborate with interdisciplinary teams to integrate cheminformatics solutions into drug discovery platforms. * Design and optimize computational workflows and front-ends for the analysis and visualization of small molecule bioactivity and ADMET data. * Manage and mentor contractors, ensuring robust project delivery and performance. * Stay updated on industry trends and emerging technologies in cheminformatics and DEL to enhance project outcomes. Required Qualifications: * PhD in Cheminformatics, Chemical Engineering, Computational Chemistry, or a related field. * Minimum of 3 years of industry experience with a proven track record of delivering end-to-end solutions from conceptualization to implementation. * Deep expertise in cheminformatics software (e.g., KNIME, OpenEye) and programming languages (e.g., Python, R). * Expertise in structure-activity relationship (SAR) analysis * Experience working in cross-functional teams & translating ideas from bench scientists to informatics solutions. * Excellent problem-solving and communication skills with a collaborative mindset. Preferred Qualifications: * Good knowledge of DNA-encoded libraries and their applications in drug discovery. * Experience with statistical analyses and machine learning techniques applied to chemistry problems. * Experience managing contractors or direct reports. * Experience leading strategic initiatives * Experience in dashboarding (e.g., Spotfire, streamlit, shiny) * Familiarity with medicinal chemistry end-user tools (e.g., LiveDesign). This is a Hybrid role available in Spring House, PA, Cambridge, MA, or San Diego, CA within the US, or Beerse, Belgium. (No fully remote option.) Travel up to approximately 10% may be required, domestic and international. Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please contact us via *******************/contact-us/careers or contact AskGS to be directed to your accommodation resource. The anticipated base pay range for this position is $115,000 to $197,800. The Company maintains highly competitive, performance-based compensation programs. Under current guidelines, this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporation's performance over a calendar/performance year. Bonuses are awarded at the Company's discretion on an individual basis. Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance. Employees may be eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)). Employees are eligible for the following time off benefits: Vacation - up to 120 hours per calendar year Sick time - up to 40 hours per calendar year Holiday pay, including Floating Holidays - up to 13 days per calendar year of Work, Personal and Family Time - up to 40 hours per calendar year Additional information can be found through the link below. ********************************************* The compensation and benefits information set forth in this posting applies to candidates hired in the United States. Candidates hired outside the United States will be eligible for compensation and benefits in accordance with their local market. #LI-SL #JNJDataScience #JNJIMRND-DS #LI-Hybrid Required Skills: Preferred Skills: Advanced Analytics, Coaching, Critical Thinking, Data Analysis, Data Privacy Standards, Data Quality, Data Reporting, Data Savvy, Data Science, Data Visualization, Digital Fluency, Econometric Models, Organizing, Process Improvements, Strategic Thinking, Technical Credibility, Workflow Analysis

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at ******************* Job Function: Discovery & Pre-Clinical/Clinical Development Job Sub Function: Translational Discovery & Development Biomarkers Job Category: Scientific/Technology All Job Posting Locations: Cambridge, Massachusetts, United States of America Job Description: About Innovative Medicine Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at *******************/innovative-medicine About Immunology Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Our Immunology team leads in the development of transformational medicines for immunological disorders and illnesses. You can influence where medicine is going by restoring health to millions of people living with immune diseases. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at *******************/innovative-medicine Translational Sciences and Medicine (TSM) is an integrated group of scientists composed of a clinical Translational Medicine (TM) team which conducts early clinical development and experimental medicine studies, and a Translational Sciences (TS) team which uses human based data and tissues to support the end to end portfolio. Together, the TSM group will provide the key learnings/insights on the next wave of novel therapies for these patients. Organizationally, TSM serves as a pivotal bridge between Discovery Research and the later phase Clinical Development group. TSM provides the necessary scientific and clinical expertise to advance an industry-leading pipeline of novel mechanism small molecules and biologic agents to address unmet need in immune-mediated diseases. TS has a broad remit stretching from support of discovery with human data to support target selection, through development of novel decision- making biomarkers for early phase clinical trials, target-centric indication sequencing and prioritization, and biomarker support of regulatory filings. It has expertise in biomarker development, disease biology research and in the application of immunology and data science technologies to support drug discovery and development. This position will reside within the Immunology Translational Sciences department and requires a highly motivated and skilled candidate to lead clinical biomarker assay development across Respiratory diseases. Respiratory Translational Sciences team leads the development of innovative therapies for respiratory immune-mediated diseases such as asthma, COPD, and other T2 and non-T2 inflammatory conditions. We are searching for the best talent for a Senior Scientist. This role is an individual contributor position where the desired candidate will ideally be a developing subject matter expert, who works independently with minimal supervision. Contributes to assay development in the lab, completes documentation associated with laboratory work, and trains and reviews the work of other laboratory members. Identifies solutions to problems pertaining to laboratory work and processes and implements them. Recent lab-based experience in T2 and non-T2 immune cell analysis and patient sample analysis relevant to asthma and COPD (e.g. sputum) is highly relevant. The successful candidate will utilize a full suite of advanced technologies to enable cutting edge research and key activities will include leading biomarker discovery efforts, assay development/validation, respiratory indication sample analysis Your role will be to: * Lead clinical biomarker assay development and execution using flow cytometry, ELISAs and other similar immunoassay platforms, RNA/DNA purification, qPCR, and/or tissue culture * Design and execute experiments to discover new biomarkers and/or assays for portfolio assets * Analyze data and communicate results to project team in a timely manner * Partner with external partners as needed to support Immunology portfolio programs * Work closely with other lab-based personnel to ensure optimal laboratory environment (collaboration, culture, safety, etc.) * Work independently and manage multiple projects simultaneously under fixed timelines * Contribute to the preparation of and submission of technical reports, prepare clear and concise summaries, and present to project teams and colleagues * Take initiative to identify, pilot and internalize emerging technical approaches that may drive increased value for portfolio execution * Deliver on study milestones and commitments and foster a collaborative, creative, and rigorous culture of scientific discovery * Coach and train junior colleagues in techniques, processes, and responsibilities. * Integrate Johnson & Johnson's Credo and Leadership Imperatives into team goals and decision-making. Qualifications / Requirements: * B.A./B.S. with 7+ years related experience OR M.S. with 6+ years research experience OR PhD with 0-2+ years research experience (academic or industry) is required * Experience in translational research in an industry setting is strongly preferred, including biomarker assay development and validation and clinical sample analysis * Experience with soluble assays and protein profiling, in vitro and ex vivo assays with immune cells is strongly preferred * Experience gaining biological insights using translational and biomarker high dimensional biological data (e.g., flow cytometry, proteomics, transcriptomics) is preferred * Self-motivated, creative, and focused; able to work within a team and to collaborate with colleagues to achieve program goals. * Attention to detail * Comfort in ambiguity and flexibility to meet the growing needs of the team and portfolio * Intellectual curiosity and excitement to learn new techniques and technologies. Subject to the terms of their respective plans, employees and/or eligible dependents are eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance. Subject to the terms of their respective plans, employees are eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)). This position is eligible to participate in the Company's long-term incentive program. Subject to the terms of their respective policies and date of hire, Employees are eligible for the following time off benefits: Vacation -120 hours per calendar year Sick time - 40 hours per calendar year; for employees who reside in the State of Washington -56 hours per calendar year Holiday pay, including Floating Holidays -13 days per calendar year Work, Personal and Family Time - up to 40 hours per calendar year Parental Leave - 480 hours within one year of the birth/adoption/foster care of a child Condolence Leave - 30 days for an immediate family member: 5 days for an extended family member Caregiver Leave - 10 days Volunteer Leave - 4 days Military Spouse Time-Off - 80 hours Additional information can be found through the link below. ********************************************* The anticipated base pay range for this position is: $104,000 - $166,750 Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via *******************/contact-us/careers , internal employees contact AskGS to be directed to your accommodation resource. #LI-Hybrid Required Skills: Assay Validation, Biomarker Analysis, Biomarker Assay Development, Biomarker Development, ELISA Techniques Preferred Skills: Biomarkers, Translational Research The anticipated base pay range for this position is : Additional Description for Pay Transparency:

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at ******************* Job Function: Data Analytics & Computational Sciences Job Sub Function: Data Science Job Category: Scientific/Technology All Job Posting Locations: Cambridge, Massachusetts, United States of America, San Diego, California, United States of America, Spring House, Pennsylvania, United States of America, Titusville, New Jersey, United States of America Job Description: Johnson & Johnson Innovative Medicine R&D Data Science and Digital Health is recruiting for a Senior Principal Data Scientist, Real World Evidence (RWE). The primary location for this position is flexible - Titusville, NJ; Raritan, NJ; Spring House, PA; Cambridge, MA; or San Diego, CA. May consider remote on a case by case basis J&J Innovative Medicine develops treatments that improve the health of people worldwide. Research and development areas encompass oncology, immunology, neuroscience, cardiopulmonary and specialty ophthalmology. Our goal is to help people live longer, healthier lives. We have produced and marketed many first-in-class prescription medications and are poised to serve the broad needs of the healthcare market - from patients to practitioners and from clinics to hospitals. To learn more about Johnson & Johnson Innovative Medicine visit *********************************** The R&D Data Science & Digital Health, Real-World Evidence (RWE) team at J&J Innovative Medicine is dedicated to developing innovative evidence solutions and critical insights through diverse data sources, including RWD, trial data and emerging innovative data sources, to support clinical programs and regulatory decision-making. The Senior Principal Data Scientist will collaborate closely with strategic partners in R&D Data Science and Digital Health, as well as multidisciplinary teams within J&J Innovative Medicine, to develop and implement evidence and insights to improve patient outcomes and accelerate clinical development in Oncology, Immunology, or Neuroscience. Key Responsibilities: * Be a hands-on technical leader, leading a portfolio of RWE projects while developing best practices and common technical tools * Support the development of the R&D RWE strategy for the generation and utilization of RWE for our key pipeline assets * End-to-end expertise in RWE studies (external control arm, novel endpoints, trial design optimization) including conceptualizing research questions, data feasibility, study design, analysis, programming, and interpretation * Assess treatment patterns and unmet needs using RWE to inform asset positioning * Ensure RWE generation aligned with regulatory requirements and scientific standards * Identify evidence opportunities and develop innovative evidence programs to support early development, registration, and post-marketing phases * Shape the selection of real-world data sources, establish data quality standards, and ensure data robustness and relevance for clinical research * Lead and develop junior researchers and programmers in executing strategies to develop RWE from concept through publication * Support regulatory interactions and meetings with scientific data packages and expertise Required Qualifications: * A Ph.D. degree, or master's degree in a quantitative field (e.g., epidemiology, biostatistics, statistics, or similar) * Relevant experience (4+ years for Ph.D., 6+ years for a master's) within biopharma companies, RWE consulting firms, or other relevant healthcare industries * Extensive hands-on experience with data engineering and exploratory data analysis, statistical modeling, time-to-event analyses, comparative effectiveness analyses, causal inference methods * Demonstrated expertise with multiple real-world data sources * Expert proficiency in R and SQL * Familiarity with data structure and programming of clinical trial data * Strong communication and influencing skills, capable of inspiring teams and driving cross-functional alignment * Highly motivated and intellectually curious, with strong executional rigor and a passion for solving complex challenges Preferred Qualifications: * Familiarity with drug discovery and the clinical development process * Expertise in oncology, Immunology or Neuroscience drug development * Experience in regulatory-grade evidence, communicating and responding to agency reviews and comments Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (********************************) or contact AskGS to be directed to your accommodation resource. #LI-GR #LI-Hybrid #JRDDS #JNJDataScience #JRD Required Skills: Preferred Skills: Advanced Analytics, Consulting, Critical Thinking, Data Analysis, Data Privacy Standards, Data Quality, Data Reporting, Data Savvy, Data Science, Data Visualization, Digital Fluency, Econometric Models, Mentorship, Strategic Thinking, Tactical Planning, Technical Credibility The anticipated base pay range for this position is : $137,000 - $235,750 Additional Description for Pay Transparency: Additional Description for Pay Transparency Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance. § Employees may be eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)). § Employees are eligible for the following time off benefits: - Vacation - up to 120 hours per calendar year - Sick time - up to 40 hours per calendar year; for employees who reside in the State of Washington - up to 56 hours per calendar year - Holiday pay, including Floating Holidays - up to 13 days per calendar year - Work, Personal and Family Time - up to 40 hours per calendar year Additional information can be found through the link below.

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at ******************* Job Function: Data Analytics & Computational Sciences Job Sub Function: Data Science Job Category: Scientific/Technology All Job Posting Locations: Cambridge, Massachusetts, United States of America, Raritan, New Jersey, United States of America, San Diego, California, United States of America, Spring House, Pennsylvania, United States of America, Titusville, New Jersey, United States of America Job Description: Johnson & Johnson Innovative Medicine R&D Data Science and Digital Health is recruiting for a Principal Data Scientist, Real World Evidence (RWE). The primary location for this position is flexible - Titusville, NJ; Raritan, NJ; Spring House, PA; Cambridge, MA; or San Diego, CA J&J Innovative Medicine develops treatments that improve the health of people worldwide. Research and development areas encompass oncology, immunology, neuroscience, cardiopulmonary and specialty ophthalmology. Our goal is to help people live longer, healthier lives. We have produced and marketed many first-in-class prescription medications and are poised to serve the broad needs of the healthcare market - from patients to practitioners and from clinics to hospitals. To learn more about Johnson & Johnson Innovative Medicine visit *********************************** The R&D Data Science & Digital Health, Real-World Evidence (RWE) team at J&J Innovative Medicine is dedicated to developing innovative evidence solutions and critical insights through diverse data sources including RWD, trial data and emerging innovative data sources, to support our clinical programs and regulatory submissions. The Principal Data Scientist will collaborate closely with strategic partners in R&D Data Science and Digital Health, as well as multidisciplinary teams within J&J Innovative Medicine, to develop and implement evidence and insights to improve patient outcomes and enhance clinical development in Oncology, Immunology, or Neuroscience. Key Responsibilities: * Contribute to the development of a portfolio of RWE projects based on RWD that will provide key insights to our pipeline assets * Leverage emerging scientific and technological developments to generate new research ideas, solutions and initiatives using real-world data * End-to-end experience in RWE studies including conceptualizing the research questions, data feasibility, study design, analysis, programming, and interpretation * Analyze and interpret data to support urgent requests from internal and external stakeholders * Ensure quality of design, execution, and publication of real-world evidence studies, and quality of models & tools * Create study protocols, statistical analysis plans, and statistical programming deliverables * Clearly articulate highly technical methods and results to diverse audiences and partners to drive decision-making * Ensure RWE generation aligned with regulatory requirements and scientific standards Required Qualifications: * A Ph.D. degree, or master's degree in a quantitative field (e.g., epidemiology, biostatistics, statistics, or similar) * Relevant experience (2+ years for Ph.D., 4+ years for a master's) within biopharma companies, RWE consulting firms, or other relevant healthcare industries * Extensive hands-on experience with data engineering and data analysis * Proven track record of consistently delivering on high impact data science projects * Expert proficiency in R and SQL * Excellent interpersonal, communication, and presentation skills Preferred Qualifications: * Experience delivering on Data Science projects using predictive technologies as machine learning/deep learning, or forecasting * Familiarity with and exposure to drug discovery and clinical development processes with one or more of the following therapeutic areas: oncology, immunology, neuroscience, or specialty ophthalmology Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (********************************) or contact AskGS to be directed to your accommodation resource. #LI-GR #LI-Hybrid #JRDDS #JNJDataScience #JRD Required Skills: Preferred Skills: Advanced Analytics, Coaching, Critical Thinking, Data Analysis, Data Privacy Standards, Data Quality, Data Reporting, Data Savvy, Data Science, Data Visualization, Digital Fluency, Econometric Models, Organizing, Process Improvements, Strategic Thinking, Technical Credibility, Workflow Analysis The anticipated base pay range for this position is : $115,000 - $197,800 Additional Description for Pay Transparency: Additional Description for Pay Transparency Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance. § Employees may be eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)). § Employees are eligible for the following time off benefits: - Vacation - up to 120 hours per calendar year - Sick time - up to 40 hours per calendar year; for employees who reside in the State of Washington - up to 56 hours per calendar year - Holiday pay, including Floating Holidays - up to 13 days per calendar year - Work, Personal and Family Time - up to 40 hours per calendar year Additional information can be found through the link below.