Explore jobs
Find specific jobs
Explore careers
Explore professions
Best companies
Explore companies
The average salary for a Principal Biostatistician in the United States stands at approximately $120,026 per year. This position plays a critical role in the healthcare and pharmaceutical industries, focusing on statistical analyses related to clinical trials and public health studies.
Salary variations occur based on factors such as experience, geographical location, and the specific industry of employment. For instance, professionals with extensive experience typically earn higher salaries, with senior roles reaching upwards of $150,000 annually.
States like California and Massachusetts are known for offering competitive salaries, often exceeding the national average. Additionally, industries such as biotechnology and pharmaceuticals tend to provide higher compensation compared to academic or governmental roles.
When considering a career as a Principal Biostatistician, it's important to evaluate both salary potential and job opportunities in your desired location. By leveraging skills in statistical software and analytical methodologies, you can enhance your value and earning prospects in this growing field.
Let Zippia find your next principal biostatistician job
Let Zippia find your next principal biostatistician job
The highest-paying states for principal biostatisticians are Washington, California, and Illinois. The lowest average principal biostatistician salary states are Alabama, Idaho, and Oklahoma.
| Rank | State | Avg. salary | Hourly rate |
|---|---|---|---|
| 1 | Illinois | $126,004 | $60.58 |
| 2 | Montana | $116,722 | $56.12 |
| 3 | Kansas | $125,950 | $60.55 |
| 4 | New York | $121,142 | $58.24 |
| 5 | District of Columbia | $121,595 | $58.46 |
| 6 | Arizona | $112,246 | $53.96 |
| 7 | Oregon | $113,074 | $54.36 |
| 8 | Maryland | $121,013 | $58.18 |
| 9 | Washington | $138,427 | $66.55 |
| 10 | North Carolina | $110,439 | $53.10 |
| 11 | Virginia | $111,530 | $53.62 |
| 12 | Massachusetts | $124,871 | $60.03 |
| 13 | Vermont | $125,012 | $60.10 |
| 14 | California | $135,155 | $64.98 |
| 15 | Pennsylvania | $104,657 | $50.32 |
| 16 | Alaska | $118,085 | $56.77 |
| 17 | New Hampshire | $101,884 | $48.98 |
| 18 | Colorado | $105,904 | $50.92 |
| 19 | Delaware | $110,556 | $53.15 |
| 20 | Rhode Island | $113,875 | $54.75 |
| 21 | Connecticut | $106,638 | $51.27 |
| 22 | South Dakota | $105,301 | $50.63 |
| 23 | Texas | $102,925 | $49.48 |
| 24 | West Virginia | $101,929 | $49.00 |
| 25 | Arkansas | $100,939 | $48.53 |
| 26 | New Jersey | $114,106 | $54.86 |
| 27 | Georgia | $102,999 | $49.52 |
| 28 | Minnesota | $97,345 | $46.80 |
| 29 | Indiana | $97,997 | $47.11 |
| 30 | Florida | $94,675 | $45.52 |
| 31 | New Mexico | $90,719 | $43.61 |
| 32 | Utah | $99,394 | $47.79 |
| 33 | Ohio | $87,061 | $41.86 |
| 34 | Tennessee | $89,593 | $43.07 |
| 35 | Nevada | $85,315 | $41.02 |
| 36 | Wisconsin | $86,952 | $41.80 |
| 37 | Nebraska | $84,732 | $40.74 |
| 38 | Mississippi | $91,556 | $44.02 |
| 39 | Kentucky | $83,739 | $40.26 |
| 40 | Missouri | $85,915 | $41.31 |
| 41 | Idaho | $74,076 | $35.61 |
| 42 | Hawaii | $94,301 | $45.34 |
| 43 | Louisiana | $85,560 | $41.13 |
| 44 | South Carolina | $80,811 | $38.85 |
| 45 | Michigan | $80,700 | $38.80 |
| 46 | Wyoming | $71,164 | $34.21 |
| 47 | North Dakota | $78,920 | $37.94 |
| 48 | Alabama | $76,439 | $36.75 |
| 49 | Maine | $70,195 | $33.75 |
| 50 | Oklahoma | $71,279 | $34.27 |
| 51 | Iowa | $65,648 | $31.56 |
The highest-paying cities for principal biostatisticians are San Francisco, CA, Seattle, WA, and Chicago, IL.
| Rank | City | Avg. salary | Hourly rate |
|---|---|---|---|
| 1 | San Francisco, CA | $141,667 | $68.11 |
| 2 | Seattle, WA | $139,365 | $67.00 |
| 3 | Chicago, IL | $126,190 | $60.67 |
| 4 | Kansas City, KS | $125,463 | $60.32 |
| 5 | Boston, MA | $125,131 | $60.16 |
| 6 | Baltimore, MD | $121,372 | $58.35 |
| 7 | New York, NY | $121,112 | $58.23 |
| 8 | Anchorage, AK | $118,934 | $57.18 |
| 9 | Newark, NJ | $114,388 | $54.99 |
| 10 | Portland, OR | $113,099 | $54.37 |
| 11 | Phoenix, AZ | $112,619 | $54.14 |
| 12 | Richmond, VA | $111,014 | $53.37 |
| 13 | Raleigh, NC | $110,954 | $53.34 |
| 14 | Wilmington, DE | $110,817 | $53.28 |
| 15 | Hartford, CT | $107,058 | $51.47 |
| 16 | Denver, CO | $105,726 | $50.83 |
| 17 | Philadelphia, PA | $105,090 | $50.52 |
| 18 | Columbus, GA | $103,973 | $49.99 |
| 19 | Dallas, TX | $103,690 | $49.85 |
| 20 | South Bend, IN | $99,315 | $47.75 |
A principal biostatistician's salary ranges from $84,000 a year at the 10th percentile to $171,000 at the 90th percentile.

| Percentile | Annual salary | Monthly salary | Hourly rate |
|---|---|---|---|
| 90th Percentile | $171,000 | $14,250 | $82 |
| 75th Percentile | $144,000 | $12,000 | $69 |
| Average | $120,026 | $10,002 | $58 |
| 25th Percentile | $99,000 | $8,250 | $48 |
| 10th Percentile | $84,000 | $7,000 | $40 |
The highest paying types of principal biostatisticians are statistical consultant, research biostatistician, and statistician.
| Job title | Annual salary | Monthly salary | Hourly rate | Job openings |
|---|---|---|---|---|
| Survey Statistician | $59,294 | $4,941 | $28.51 | 14,315 |
| Statistician | $84,726 | $7,061 | $40.73 | 17,782 |
| Mathematical Statistician | $62,612 | $5,218 | $30.10 | 18,100 |
| Research Biostatistician | $88,264 | $7,355 | $42.43 | 63,150 |
Top companies hiring principal biostatisticians now:
Principal biostatistician salaries at Memorial Sloan Kettering Cancer Center and Quidel are the highest-paying according to our most recent salary estimates. In addition, the average principal biostatistician salary at companies like Neurocrine Biosciences and Biogen are highly competitive.
| Rank | Company | Average salary | Hourly rate |
|---|---|---|---|
| 1 | Memorial Sloan Kettering Cancer Center | $160,741 | $77.28 |
| 2 | Quidel | $152,023 | $73.09 |
| 3 | Neurocrine Biosciences | $141,598 | $68.08 |
| 4 | Biogen | $133,798 | $64.33 |
| 5 | Adaptimmune | $130,558 | $62.77 |
| 6 | Parexel International | $129,745 | $62.38 |
| 7 | UCB | $129,547 | $62.28 |
| 8 | Sanofi US | $129,157 | $62.09 |
| 9 | Allergan plc | $128,808 | $61.93 |
| 10 | Vertex Pharmaceuticals | $128,629 | $61.84 |
| 11 | Regeneron | $127,954 | $61.52 |
| 12 | Wyeth Biopharma | $127,766 | $61.43 |
| 13 | Shionogi | $127,470 | $61.28 |
| 14 | Incyte | $127,303 | $61.20 |
| 15 | Cytel | $127,273 | $61.19 |
| 16 | Boehringer Ingelheim | $127,226 | $61.17 |
| 17 | Pharmaceutical Research Associates, Inc. | $126,648 | $60.89 |
| 18 | Seattle Children's Healthcare System | $126,062 | $60.61 |
| 19 | Sanofi Genzyme | $125,750 | $60.46 |
| 20 | Edwards Lifesciences | $125,150 | $60.17 |
The average principal biostatistician salary has risen by $23,922 over the last ten years. In 2014, the average principal biostatistician earned $96,104 annually, but today, they earn $120,026 a year. That works out to a 15% change in pay for principal biostatisticians over the last decade.
Compare principal biostatistician salaries for cities or states with the national average over time.
Compare principal biostatistician salaries for individual cities or states with the national average.
| Year | Avg. salary | Hourly rate | % Change |
|---|---|---|---|
| 2025 | $120,000 | $57.70 | +1.2% |
| 2024 | $119,000 | $57.01 | +3.7% |
| 2023 | $114,000 | $54.90 | +4.2% |
| 2022 | $109,000 | $52.57 | +4.2% |
| 2021 | $105,000 | $50.34 | +0.5% |
| Company | Job | Location | Date added | Salary |
|---|---|---|---|---|
| Iqvia | Principal Biostatistician FSP, Early Phase | Durham, NC | 06/27/2025 | $122,800 |
| Novartis AG | Senior Principal Biostatistician | East Hanover, NJ | 06/25/2025 | $119,700 |
| Precision Medicine Group | Principal Biostatistician | Peapack and Gladstone, NJ | 06/24/2025 | $133,000 |
| Cleerly, Inc. | Principal Biostatistician, Senior | Denver, CO | 06/16/2025 | $198,000 |
| Cleerly, Inc. | Principal Biostatistician, Senior | New York, NY | 06/16/2025 | $237,000 |
| Xenon Pharmaceuticals Inc. | Principal Biostatistician | Boston, MA | 06/12/2025 | $126,700 |
| Syneos Health, Inc. | Principal Biostatistician (LP Oncology-US Remote) | Morrisville, NC | 06/12/2025 | $95,000 |
| Calico | Principal Biostatistician | South San Francisco, CA | 06/09/2025 | $198,000 |
| Biogen Idec | Senior Principal Biostatistician | Cambridge, MA | 05/29/2025 | $138,000 |
| Neurocrine Biosciences | Principal Biostatistician-(SD Based Preferred) | San Diego, CA | 05/27/2025 | $128,200 |
Search for principal biostatistician jobs