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Principal biostatistician salary

Average principal biostatistician salary

$120,026

$57.7 hourly rate

Entry-level principal biostatistician salary
$84,000 yearly salary
Updated December 15, 2025

Understanding Principal Biostatistician Salaries

The average salary for a Principal Biostatistician in the United States stands at approximately $120,026 per year. This position plays a critical role in the healthcare and pharmaceutical industries, focusing on statistical analyses related to clinical trials and public health studies.

Salary variations occur based on factors such as experience, geographical location, and the specific industry of employment. For instance, professionals with extensive experience typically earn higher salaries, with senior roles reaching upwards of $150,000 annually.

States like California and Massachusetts are known for offering competitive salaries, often exceeding the national average. Additionally, industries such as biotechnology and pharmaceuticals tend to provide higher compensation compared to academic or governmental roles.

When considering a career as a Principal Biostatistician, it's important to evaluate both salary potential and job opportunities in your desired location. By leveraging skills in statistical software and analytical methodologies, you can enhance your value and earning prospects in this growing field.

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Where can a Principal Biostatistician earn more?

Compare salary by location
Vs
169k
149k
129k
109k
89k
69k
Columbus, OH$141,667
South Bend, IN$99,315
Compare salary by company
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175k
155k
135k
115k
95k
Memorial Sloan Kettering Cancer Center$160,741
Edwards Lifesciences$125,150

Principal biostatistician salaries by experience level

Principal biostatistician salary estimates from across the web

Based on the latest salary information compiled by Zippia, Salary.com, Glassdoor and Comparably, the average salary for a principal biostatistician typically falls between $96,289 and $160,967.
zippia
$120,026yearly
glassdoor[1]
$160,967yearly
comparably[2]
$96,289yearly
Salary.com[3]
$102,896yearly

Average principal biostatistician salary by state

The highest-paying states for principal biostatisticians are Washington, California, and Illinois. The lowest average principal biostatistician salary states are Alabama, Idaho, and Oklahoma.

  • State view
  • County view
Average salary:

Highest paying states for principal biostatisticians

RankStateAvg. salaryHourly rate
1Illinois$126,004$60.58
2Montana$116,722$56.12
3Kansas$125,950$60.55
4New York$121,142$58.24
5District of Columbia$121,595$58.46
6Arizona$112,246$53.96
7Oregon$113,074$54.36
8Maryland$121,013$58.18
9Washington$138,427$66.55
10North Carolina$110,439$53.10
11Virginia$111,530$53.62
12Massachusetts$124,871$60.03
13Vermont$125,012$60.10
14California$135,155$64.98
15Pennsylvania$104,657$50.32
16Alaska$118,085$56.77
17New Hampshire$101,884$48.98
18Colorado$105,904$50.92
19Delaware$110,556$53.15
20Rhode Island$113,875$54.75
21Connecticut$106,638$51.27
22South Dakota$105,301$50.63
23Texas$102,925$49.48
24West Virginia$101,929$49.00
25Arkansas$100,939$48.53
26New Jersey$114,106$54.86
27Georgia$102,999$49.52
28Minnesota$97,345$46.80
29Indiana$97,997$47.11
30Florida$94,675$45.52
31New Mexico$90,719$43.61
32Utah$99,394$47.79
33Ohio$87,061$41.86
34Tennessee$89,593$43.07
35Nevada$85,315$41.02
36Wisconsin$86,952$41.80
37Nebraska$84,732$40.74
38Mississippi$91,556$44.02
39Kentucky$83,739$40.26
40Missouri$85,915$41.31
41Idaho$74,076$35.61
42Hawaii$94,301$45.34
43Louisiana$85,560$41.13
44South Carolina$80,811$38.85
45Michigan$80,700$38.80
46Wyoming$71,164$34.21
47North Dakota$78,920$37.94
48Alabama$76,439$36.75
49Maine$70,195$33.75
50Oklahoma$71,279$34.27
51Iowa$65,648$31.56

Highest paying cities for principal biostatisticians

The highest-paying cities for principal biostatisticians are San Francisco, CA, Seattle, WA, and Chicago, IL.

RankCityAvg. salaryHourly rate
1San Francisco, CA$141,667$68.11
2Seattle, WA$139,365$67.00
3Chicago, IL$126,190$60.67
4Kansas City, KS$125,463$60.32
5Boston, MA$125,131$60.16
6Baltimore, MD$121,372$58.35
7New York, NY$121,112$58.23
8Anchorage, AK$118,934$57.18
9Newark, NJ$114,388$54.99
10Portland, OR$113,099$54.37
11Phoenix, AZ$112,619$54.14
12Richmond, VA$111,014$53.37
13Raleigh, NC$110,954$53.34
14Wilmington, DE$110,817$53.28
15Hartford, CT$107,058$51.47
16Denver, CO$105,726$50.83
17Philadelphia, PA$105,090$50.52
18Columbus, GA$103,973$49.99
19Dallas, TX$103,690$49.85
20South Bend, IN$99,315$47.75

Principal biostatistician salary details

A principal biostatistician's salary ranges from $84,000 a year at the 10th percentile to $171,000 at the 90th percentile.

Average principal biostatistician salary graph
Average principal biostatistician salary graph, trends, and summary

What is a principal biostatistician's salary?

PercentileAnnual salaryMonthly salaryHourly rate
90th Percentile$171,000$14,250$82
75th Percentile$144,000$12,000$69
Average$120,026$10,002$58
25th Percentile$99,000$8,250$48
10th Percentile$84,000$7,000$40

Highest paying principal biostatistician jobs

The highest paying types of principal biostatisticians are statistical consultant, research biostatistician, and statistician.

Job titleAnnual salaryMonthly salaryHourly rateJob openings
Survey Statistician$59,294$4,941$28.5114,315
Statistician$84,726$7,061$40.7317,782
Mathematical Statistician$62,612$5,218$30.1018,100
Research Biostatistician$88,264$7,355$42.4363,150

Top companies hiring principal biostatisticians now:

  1. Memorial Sloan Kettering Cancer Center jobs (3)
  2. Biogen jobs (13)
  3. Parexel International jobs (6)
  4. Sanofi US jobs (3)
  5. Vertex Pharmaceuticals jobs (16)

Which companies pay principal biostatisticians the most?

Principal biostatistician salaries at Memorial Sloan Kettering Cancer Center and Quidel are the highest-paying according to our most recent salary estimates. In addition, the average principal biostatistician salary at companies like Neurocrine Biosciences and Biogen are highly competitive.

RankCompanyAverage salaryHourly rate
1Memorial Sloan Kettering Cancer Center$160,741$77.28
2Quidel$152,023$73.09
3Neurocrine Biosciences$141,598$68.08
4Biogen$133,798$64.33
5Adaptimmune$130,558$62.77
6Parexel International$129,745$62.38
7UCB$129,547$62.28
8Sanofi US$129,157$62.09
9Allergan plc$128,808$61.93
10Vertex Pharmaceuticals$128,629$61.84
11Regeneron$127,954$61.52
12Wyeth Biopharma$127,766$61.43
13Shionogi$127,470$61.28
14Incyte$127,303$61.20
15Cytel$127,273$61.19
16Boehringer Ingelheim$127,226$61.17
17Pharmaceutical Research Associates, Inc.$126,648$60.89
18Seattle Children's Healthcare System$126,062$60.61
19Sanofi Genzyme$125,750$60.46
20Edwards Lifesciences$125,150$60.17

Wage gap by gender, race and education

$118,000$116,800$115,600$114,400$113,200$112,000
MaleFemale

Principal biostatistician salary trends

The average principal biostatistician salary has risen by $23,922 over the last ten years. In 2014, the average principal biostatistician earned $96,104 annually, but today, they earn $120,026 a year. That works out to a 15% change in pay for principal biostatisticians over the last decade.

Compare principal biostatistician salaries for cities or states with the national average over time.

Average principal biostatistician salary over time

Compare principal biostatistician salaries for individual cities or states with the national average.

Principal biostatistician salary by year

YearAvg. salaryHourly rate% Change
2025$120,000$57.70+1.2%
2024$119,000$57.01+3.7%
2023$114,000$54.90+4.2%
2022$109,000$52.57+4.2%
2021$105,000$50.34+0.5%

Recently added principal biostatistician salaries

CompanyJobLocationDate addedSalary
IqviaPrincipal Biostatistician FSP, Early PhaseDurham, NC06/27/2025$122,800
Novartis AGSenior Principal BiostatisticianEast Hanover, NJ06/25/2025$119,700
Precision Medicine GroupPrincipal BiostatisticianPeapack and Gladstone, NJ06/24/2025$133,000
Cleerly, Inc.Principal Biostatistician, SeniorDenver, CO06/16/2025$198,000
Cleerly, Inc.Principal Biostatistician, SeniorNew York, NY06/16/2025$237,000
Xenon Pharmaceuticals Inc.Principal BiostatisticianBoston, MA06/12/2025$126,700
Syneos Health, Inc.Principal Biostatistician (LP Oncology-US Remote)Morrisville, NC06/12/2025$95,000
CalicoPrincipal BiostatisticianSouth San Francisco, CA06/09/2025$198,000
Biogen IdecSenior Principal BiostatisticianCambridge, MA05/29/2025$138,000
Neurocrine BiosciencesPrincipal Biostatistician-(SD Based Preferred)San Diego, CA05/27/2025$128,200

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