Principal research scientist jobs in Greensboro, NC

Would you like to join an international team working to improve the future of healthcare? Do you want to enhance the lives of millions of people? Grifols is a global healthcare company that since 1909 has been working to improve the health and well-being of people around the world. We are leaders in plasma-derived medicines and transfusion medicine and develop, produce and market innovative medicines, solutions and services in more than 110 countries and regions. **Summary** This position is in the New Proteins & Technology group, within the Protein Discovery Department, and will report to the New Proteins &Technology Associate Director. We are seeking a highly motivated and experienced individual with a PhD and a strong background in pharmaceuticals across a variety of disease areas. The individual within this position will work with other members of the New Protein and Technology group, across the Global Protein Discovery department, and other cross-functional teams to develop and move projects forward using both internal and external resources that best suit the project in question. The successful candidate will be responsible for conducting comprehensive evaluations of proteins and opportunities both within Grifols' therapeutic areas of interest and also those that fall outside the company's primary therapeutic areas. This will involve a deep understanding of protein function and disease pathobiology, as well as the ability to apply this knowledge to the identification and development of novel therapies using those proteins. The individual will be responsible for steering the direction of these projects, involving active participation in and leadership of the research design and execution of projects. Accomplishing this will involve detailed data analysis and interpretation from a variety of sources (cell-based and biochemical assays, in vivo studies, omics data, protein purification). Experience writing grants and working with biomedical intelligence platforms is a plus. Furthermore, the individual will be tasked with participating in and performing lab activities to support these projects when the need arises. The position requires excellent communication skills to effectively identify, establish, and maintain collaborations with external expert partners, as well as present findings to the internal teams. The ability to work in a fast-paced environment and adapt to changing priorities is essential. This role offers the opportunity to contribute to cutting-edge research and make a significant impact on our therapeutic pipeline. **Primary responsibilities for role:** + Responsible for developing functional area objectives in support of departmental objectives/corporate goals. + Represents the functional area on a cross-functional team + Identifies and requests needed resources within or across functional areas. + Independently writes and critically edits procedures or technical reports of a complex nature, assimilating information across functional areas, suitable for regulatory submission or external publication. + Directs resources in the preparation of procedures or technical reports of a complex nature suitable for regulatory submission or external publication. + Communicates technical and project results and critical information to technical and/or non-technical audiences. + Develops creative, novel programs to meet corporate objectives and open new business opportunities. + Capable of leading others in problem-solving efforts. + Contributes to the development of new principles or concepts. + Independently designs, executes, and interprets results for novel and scientifically complex study programs. + Mentors others in experimental design. + Capable of directing others in study execution. **Additional Responsibilities** + Maintains laboratory facilities in accordance with company policies and industrial best practices. + Provides support for research and developmental studies, clinical or commercial manufacturing as needed. + Identifies, implements, and qualifies, as necessary, equipment to meet industrial best practices or achieve compliance with regulatory expectations. **Knowledge, Skills, and Abilities:** + Capable of developing resource plans to achieve identified objectives/goals. + Advanced ability to set and meet deadlines, multitask, as well as to identify, request, and prioritize resources across functional area based on project needs. + Demonstrates advanced critical judgment and strategic thinking in representing functional area concerns on cross functional teams. + Experienced in identifying projects risks. + Must demonstrate advanced ability to produce, oversee, and/or deliver written and oral presentations for technical and leadership audiences. + Independently applies sound scientific principles in development of innovative solutions to complex technical problems. + Advanced ability to creatively apply scientific principles in problem solving in potentially novel areas. + Advanced ability to apply standardized root cause analysis, investigation tools and methodologies. + Recognized and consulted as an expert in professional field within functional area or externally. + Broad knowledge and expertise of modern scientific technologies commonly used in functional area. + Evidence of patent and/or publication record in peer-reviewed journals. + Proficient with the use of MS Office software. **Education & Experience:** + Educational degrees must be relevant to position (e.g., Biology, Biochemistry, Chemistry, or Toxicology) + A Bachelor's degree with at least 12 years of experience + A Master's degree with at least 10 years of experience + A PhD with at least 8 years of experience **Equivalency:** Depending on the area of assignment, directly related experience or a combination of directly related education and experience and/or competencies may be considered in place of the stated requirements. Example: If a job level requires a Bachelor's degree plus 4 years of experience, an equivalency could include 8 years of experience, an Associate's degree with 6 years of experience, or a Master's degree with 2 years of experience. Third Party Agency and Recruiter Notice: Agencies that present a candidate to Grifols must have an active, nonexpired, Grifols Agency Master Services Agreement with the Grifols Talent Acquisition Department. Additionally, agencies may only submit candidates to positions that they have been engaged to work on by a Grifols Recruiter. All resumes must be sent to a Grifols Recruiter under these terms or they will be considered a Grifols candidate. **Grifols provides equal employment opportunities to applicants and employees without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other characteristic or status protected by law. We will consider for employment all qualified Applicants in a manner consistent with the requirements of applicable state and local laws.** Learn more about Grifols (************************************** **Req ID:** 536556 **Type:** Regular Full-Time **Job Category:** R & D

R&D Scientist Department Research and Development Manager Director of R&D Job Type (DOL Status) Location Burlington, NC Job Details Company Background Alamance is recognized as a leading manufacturer of aerosol whipped cream, flavored drinks, freeze pops, and bottled water, offering beloved brands like Classic Cream, Fun Pops, Coffee Toppers, Whipt, and Groovy Glacier. We produce, pack and ship private labels based on customer specific needs. An innovative company with proven experience in creating exciting new products that redefine what is possible in the food and beverage manufacturing industry. Position Overview: We are seeking an innovative and driven R&D Scientist to join our team focusing on Food Service and Internal Development. This individual will lead development projects from concept through commercialization, emphasizing food service customer solutions and continuous improvement of our aerosol product line. The ideal candidate will have 1-3 years of hands-on experience in food & beverage product development, strong project management skills, and a desire to grow within a collaborative, fast-paced R&D environment. Preference will be given to candidates with experience in dairy, non-dairy, and aerosol technologies. This role requires active external communication with food service partners and close collaboration with our R&D Corporate Chef to bring innovative solutions to life. Essential Duties/Responsibilities: Lead development of new food service products, line extensions, and internal aerosol innovation projects. Translate customer and business needs into technically feasible and commercially viable solutions. Manage multiple projects ensuring timelines, technical milestones, and scale-up success. Develop expertise in formulation, functionality, and manufacturing requirements across product categories. Collaborate cross-functionally with Operations, Sales, QA, and Commercialization teams. Conduct benchtop and pilot plant testing, analyze data, and refine prototypes based on feedback. Participate in external customer meetings, technical discussions, and product presentations. Work with the R&D Corporate Chef to develop food service concepts and finished product applications. Stay current on emerging trends, technologies, and competitive landscape. Document formulas, processes, and technical findings in accordance with internal protocols. Qualifications: B.S. or M.S. in Food Science or related field. 1-3 years of relevant R&D experience in food & beverage product development. Experience with aerosol, dairy, or non-dairy systems preferred. Strong understanding of ingredient functionality, food formulation, and processing. Proven ability to manage multiple projects independently in a fast-paced environment. Strong organizational, analytical, and communication skills. Experience in customer-facing communication or external collaboration preferred. Open-minded and adaptable to company-specific practices. Comfortable working hands-on in lab, pilot, and plant settings. Education/Training/Certifications: Bachelor's or Master's degree in Food Science or related discipline. Related Experience: 1 to 3 years in food & beverage product development with exposure to dairy, non-dairy, or aerosol technologies. Knowledge/Skills/Experience: Product formulation and processing expertise. Project management and cross-functional collaboration. Customer communication and presentation skills. Travel Requirements: Occasional travel to customer sites and external meetings as needed. Physical Requirements: Standing Walking Sitting Use of hands, fingers Reaching with hands and arms Climb and balance Stoop, kneel, crouch or crawl Talk and hear Distance vision (clear vision at 20 feet or more) Color vision (ability to identify and distinguish colors) Peripheral vision (ability to observe areas outside direct line of sight) Depth perception (three-dimensional vision, ability to judge distances and spatial relationships) Alamance Foods Inc. is an equal opportunity employer and does not discriminate against persons because of age, race, color, creed, religion, disability, gender, ethnic or national origin, or veteran status. Alamance Foods Inc. prohibits discrimination against individuals with disabilities and will reasonably accommodate applicants with a disability, upon request, and will also ensure reasonable accommodation for employees with a disability. Employment Eligibility: Alamance Foods Inc. participates in the federal E-Verify program. All employment is contingent upon the successful completion of a Form I-9 and verification of authorization to work in the United States.

Requirements Advanced degree (e.g., M.D., Ph.D., J.D.) or equivalent experience Five years of professional experience Peer-reviewed publications Demonstrated experience securing and managing funded grants or contracts

A global higher education leader in innovative teaching, research and public service, the University of North Carolina at Chapel Hill consistently ranks as one of the nation's top public universities. Known for its beautiful campus, world-class medical care, commitment to the arts and top athletic programs, Carolina is an ideal place to teach, work and learn. One of the best college towns and best places to live in the United States, Chapel Hill has diverse social, cultural, recreation and professional opportunities that span the campus and community. University employees can choose from a wide range of professional training opportunities for career growth, skill development and lifelong learning and enjoy exclusive perks for numerous retail, restaurant and performing arts discounts, savings on local child care centers and special rates on select campus events. UNC-Chapel Hill offers full-time employees a comprehensive benefits package, paid leave, and a variety of health, life and retirement plans and additional programs that support a healthy work/life balance. Primary Purpose of Organizational Unit The Chemistry Department is one of the largest and most complex departments in the College of Arts & Sciences. There are 43 faculty members, 44 SHRA and EHRA staff positions, 260 graduate students, 33 postdoctoral research associates, 700 undergraduate majors, and an annual total of approximately 10,000 registrations by all students in classroom and laboratory courses. The Department is housed in five buildings with over 580,000 sq. feet of space. The faculty participate in teaching assignments which involve an average of 200 students per faculty member per semester. The majority of faculty are research active and supervise graduate students working on their Masters or Ph.D. degrees, undergraduate students carrying out independent research and honors programs, research technicians and postdoctoral research associates. Primarily the research is funded by federal and private agencies such as NSF, NIH, Army, Navy, DOE, PRF and involves expenditures of more than nineteen million dollars annually. A total of over thirty-two million dollars from all sources is expended annually in the Department. Position Summary The Lead Research Chemist working on the PFAS (per- and polyfluoroalkyl substances) Remediation Pilot project, funded through the NC Policy Collaboratory, will be the driver of innovation for the materials at the center of this project, will help to manage a team of researchers focused on materials development, and will provide consultation on chemistry opportunities and constraints for the manufacturing and engineering teams. To complement and enhance the skills of the candidate, the position will include opportunities for continued professional development in the areas of chemistry, leadership, and translational science. Minimum Education and Experience Requirements Relevant post-Baccalaureate degree required (or foreign degree equivalent); for candidates demonstrating comparable independent research productivity, will accept a relevant Bachelor's degree (or foreign degree equivalent) and 3 or more years of relevant experience in substitution. May require terminal degree and licensure. Required Qualifications, Competencies, and Experience * The position will require a talented candidate with a combination of deep knowledge in polymer chemistry and excellent leadership potential * Demonstrated skills in small molecule and polymer synthesis, to include the synthesis of small molecules with high purity and the synthesis of polymers through different mechanisms * Demonstrated skills in chemical characterization, to include proficiency in nuclear magnetic resonance spectroscopy, infra-red spectroscopy, size exclusion chromatography, and calorimetry. * Demonstrated ability to function effectively in a fast-paced environment subject to frequent interruptions and changes in priorities. * Demonstrated ability to manage diverse individuals constructively toward a common goal. * Recent experience in training or teaching laboratory personnel. * Excellent oral and written communication skills, with the ability to interact productively with a diverse group of individuals, edit and compile materials from multiple sources, and tailor information to various purposes required. Preferred Qualifications, Competencies, and Experience Experience with high resolution liquid chromatography mass spectrometry is a plus Special Physical/Mental Requirements Campus Security Authority Responsibilities Not Applicable. Special Instructions Quick Link *******************************************

The Tiley Lab is seeking to fill a temporary Research Scientist/Scholar position with expertise conducting research on quantitative targeted proteomics using LC-MS/MS in tissues and cells from humans. This project will be funded by the NIH - NICHD InTEC UC2 Grant. Active dates: July 1-September 1 2025. The Integrated Transporter Elucidation Center (InTEC) is a consortium of multiple universities that aims to advance our understanding of how placental transporters impact the disposition of endobiotics, xenobiotics, and overall pregnancy health. Funded by NICHD , InTEC utilizes novel technologies to profile the SLC and ABC transporter proteome, predict and validate novel substrates and regulators of placental transport, and simulate maternal-fetal disposition using a vascularized placenta-on-a-chip. The University of North Carolina ( UNC ) at Chapel Hill, Eshelman School of Pharmacy, Division of Pharmacotherapy and Experimental Therapeutics ( DPET ) is part of InTEC and is seeking to identify placental transport proteins measurable by targeted proteomics and to create new methods to improve detectability of transport proteins. The division works closely with all InTEC institutions (Rutgers University, Tulane University and the University of Pennsylvania) and with other divisions within the UNC Eshelman School of Pharmacy. Required Qualifications, Competencies, And Experience Relevant post-Baccalaureate degree required (or foreign degree equivalent); for candidates demonstrating comparable independent research productivity, will accept a relevant Bachelor's degree (or foreign degree equivalent) and 3 or more years of relevant experience in substitution. May require terminal degree and licensure. Preferred Qualifications, Competencies, And Experience - Ph.D. in Pharmacology and Toxicology, or related field. - Previous experience in LC-MS/MS targeted proteomics and tissue and cell sample preparation.

The Cell Therapy Process Development Scientist will play a critical role in the development and optimization of robust and reproducible processes for the manufacturing of ProKidney's cell therapy product, Rilparencel, which is in phase three clinical trial. The process development scientist will design and execute studies and implementation of cutting-edge technologies for commercial production. You will work in a fast-paced, highly collaborative environment, engaging with various internal teams, external partners, and key stakeholders to ensure the seamless transition of processes from the laboratory to clinical and, eventually, commercial production. This role offers an exciting opportunity to make a direct impact on the development of life-saving therapies while applying your scientific expertise to solve complex challenges in cell therapy. Key Responsibilities Design and execute studies to develop and optimize cell therapy manufacturing processes, including cell expansion, selection, purification, formulation, and cryopreservation. Analyze and interpret experiment results. Write and review study reports. Design and implement process improvements that reduce cost, improve efficiency, and enhance product quality, while maintaining compliance with regulatory requirements. Work closely with Manufacturing teams to ensure smooth technology transfer and the successful execution of GMP manufacturing runs, ensuring process robustness and troubleshooting any issues that arise. Perform process risk assessment using tools including FMEA. Design and execute experimental plans to characterize and validate critical process parameters (CPPs) of cell therapy products. Participate in project teams and contribute technical expertise to support the transition from pre-clinical to clinical and commercial manufacturing. Stay current with the latest trends, technologies, and regulatory developments in the cell therapy field. Contribute to scientific publications, presentations, and internal knowledge sharing. Qualifications Degree in Biotechnology, Biochemical Engineering, Chemical Engineering, Cell Biology, Bioengineering, or a related discipline. PhD with 2+ years experience, MS with 8+ years experience, or BS with 12+ years experience in bioprocess or cell therapy process development. Extensive hands-on experience with cell expansion, cell selection and cell purification. Proven track record of contributing to successful technology transfer of manufacturing processes. Experience in QbD and process characterization including the use of DoE (Design of Experiments) and statistical analysis. Knowledge of analytical methods such as flow cytometry, PCR, ELISA, cell counting, and other assays for cell therapy characterization. Excellent problem-solving skills and the ability to troubleshoot complex process-related challenges. Strong communication skills, with the ability to articulate complex technical information to both technical and non-technical stakeholders. Self-motivated, detail-oriented, and able to manage multiple priorities effectively in a fast-paced, dynamic environment. Strong interpersonal skills and the ability to work collaboratively in a cross-functional, multidisciplinary team. Preferred Qualifications Experience in preparing regulatory filings. Familiarity with data analysis software (e.g., JMP). Experience in GMP regulations. ProKidney is an equal employment opportunity employer and does not discriminate against any applicant because of race, creed, color, age, national origin, ancestry, religion, gender, sexual orientation, disability, genetic information, veteran status, military status, application for military service or any other class protected by state or federal law. Applicants must be eligible to work in the United States without the need for work visa or residency sponsorship.

Senior Scientist Real-World Evidence Winston-Salem, North Carolina **Reynolds American is evolving at pace into a global multi-category business. Our purpose is to create A Better Tomorrow by Building a Smokeless World.** **To achieve our ambition, we are looking for colleagues who are ready to join us on this journey! Tomorrow can't wait, let's shape it together!** **REYNOLDS AMERICAN has an exciting opportunity for a Senior Manager Real-World Evidence in Winston-Salem, NC.** The Senior Scientist Real-World Evidence, will provide expertise in managing the planning, execution, monitoring, and closing of clinical research to support regulatory submissions and real-world experiences of our products. In this position, the individual will collaborate on projects and programs related to actual use observational studies to support regulatory submissions for current and future market products. Additionally, this position will contribute to generating scientific evidence to support tobacco harm reduction initiatives. This role will participate in cross-functional collaborations and build relationships with internal and external partners to influence regulatory science strategy and deliver evidence generation. Further, this role will bring ingenuity and creativity to independently develop and recommend solutions to complex problems. This person will deliver evidence generation while maintaining high scientific standards and integrity, and adhering to all applicable regulations and procedures. This position requires strong technical, project management, and communication skills. A strong background in observational and/or clinical research is desired. **Your key responsabilities will include:** + Significantly contribute to the operational planning and execution of clinical studies (e.g., actual use trials, pragmatic trials) for tobacco products intended for FDA regulatory submissions. + Act as the primary liaison between clinical research teams, vendors, and cross-functional stakeholders. + Develop and manage detailed project plans, timelines, budgets, and resource allocations. + Assist in the generation of scientific evidence to influence regulatory science strategy + Project management across multiple projects with internal and external stakeholders + Provide insight into scientific study design and data interpretation across a variety of social and behavioral scientific disciplines + Regulatory science engagement through publications, conference presentations, and external collaborations + Regulatory writing and scientific and regulatory engagement **What are we looking for?** + Advanced degree (Ph.D. or M.S.) in epidemiology,chemistry, biology, toxicology, pharmacology, clinical or social science, or other relevant discipline + 2+ years relevant scientific experience resulting in a thorough knowledge of concepts, principles and strategic relevance as pertains toconducting randomized controlled trials and observational research studies + Experience working in a regulated industry, such as tobacco/nicotine, pharmaceutical, and/or medical device + Demonstrated ability to manage and execute multiple projects + Strong organizational, writing, presentation, and communication skills, with the ability to interface with other functions within (and external to) the Company + Ability to conceive, plan and conduct work streams aligned with, and in support of, regulatory strategy + Strong ability to apply critical thinking to ambiguous or complex scientific challenges + Extensive experience navigating tobacco regulatory frameworks and proficiency in biostatistics or data interpretation is considered beneficial **WE ARE REYNOLDS AMERICAN-A member of the BRITISH AMERICAN TOBACCO GROUP** At Reynolds American, we are committed to our Purpose of creating A Better Tomorrow. This is what drives our people and our passion for innovation. **See what is possible for you at REYNOLDS AMERICAN.** **BELONGING, ACHIEVING, TOGETHER** Collaboration and teamwork underpin everything we do here at Reynolds American. We know that collaborating with colleagues is what makes us stronger and best prepared to meet our business goals. **BENEFITS OVERVIEW** **Benefit Information** The following is a general summary of the competitive compensation and benefit plans we offer: - 401(k) plan that offers opportunity to save on pre- and post-tax basis up to 50 percent of eligible compensation. o Company matches 100 percent of employee pre-tax/Roth (401k) contributions up to six percent o Company contributes an additional three percent to 401(k) whether employee participates or not - Comprehensive health- and welfare-benefits package (including medical, dental, vision, and prescription drugs) - Health Savings Account start-up contribution for employees who elect the high deductible health plan - Flexible spending accounts for both Health Care and Dependent Care allowing employee to use pre-tax dollars to pay for qualified expenses during the calendar year - Employee assistance program offering 8 free counselling sessions, per issue, each calendar year for employees and their dependents - Company paid life insurance of 1x annual base pay ($50,000 minimum) - Company paid accidental death or dismemberment insurance of 2x annual base pay ($50,000 minimum) - Voluntary insurances offered at group rates: employee and dependent life insurance, AD&D insurance, critical illness, accident coverage, disability buy-up, and auto & home insurance - Tuition reimbursement and student loan support - Dependent Scholarship Programs - Free confidential personal financial counselling service - On-site health centers and 24/7 fitness centers at certain company locations - A charitable giving matching grants program that enables employees to direct and double their donations to qualifying charitable organizations of their choice - Health-care concierge service - Volunteer service opportunities - Extensive training opportunities - Company vehicle for eligible employees - Mobile phone allowance for eligible employees - Paid Leave: o Sick and Personal Time (exempt employees may be excused with pay for brief absences; non-exempt employees receive up to 6 days) o Vacation (levels Below Senior Director receive 15 days (pro-rated during first year of service); Senior Director and Officers receive 25 days (pro-rated during first year of service)). o Holidays (Nine company recognized and two annual personal holidays to be used at the employee's discretion) o Paid Parental Leave + temporary reduced work schedule opportunity o Funeral Leave o Short-Term Disability Leave o Long-Term Disability Leave o Jury Duty Leave o Military Leave o Released Time for Children's Education o Community Outreach Leave o Other paid leave benefits, as required by state or local law - Your journey with us isn't limited by boundaries; it's propelled by your aspirations. Join us at Reynolds American and become a part of an environment that thrives on internal advancement, where your career progression isn't just a statement - it's a reality we're eager to build together. Seize the opportunity and own your development; your next chapter starts here. - You'll have access to online learning platforms and personalized growth programs to nurture your leadership skills - We prioritise continuous improvement within a transformative environment, preparing for ongoing changes Our organization offers a level of challenge, responsibility, and creativity for motivated employees who want to grow their careers. We are also committed to valuing different perspectives, experiences, and talents to improve the company's potential for optimally achieving its business objectives! Reynolds American Inc. and its affiliated companies is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to age, race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other status protected by law. Only applicants requiring reasonable accommodation for any part of the application and hiring process should contact us directly via email at *******************

**City** Greensboro **Role Type** Permanent **WHO WE ARE** ITG Brands is the third-largest tobacco company in the USA with offerings of some of the most well-known cigarette, cigar, and e-vapor brands. As a member of the globally recognized Imperial Brands PLC family, we are a forward-thinking partner with operational integrity. ITG Brands is committed to putting consumers at the center of what we do, while creating an innovative workplace where inclusion, creativity, and bold thinking drive progress. This empowers us to bring our true selves to work, to collaborate more effectively through showing our passion and being confident to bring new ideas to the table. We are not afraid to seize opportunities and make things happen - both individually and collaboratively. We strive to exceed expectations by seeing things differently and doing things differently. This truly is a place where we all share a challenger mindset which drives our success. **What You Will Do** - JOB SUMMARY The Senior Toxicologist plays a pivotal role in shaping regulatory strategy and scientific direction for tobacco product submissions, including Premarket Tobacco Product Applications (PMTAs). They manage the toxicological risk assessment programs for both conventional and reduced-risk tobacco products, ensuring the data is scientifically robust and supports the product's marketing approval. - WHAT YOU WILL DO Lead the development of toxicology strategies for PMTA and other regulatory submissions, ensuring alignment with FDA expectations and public health standards. Oversee and conduct human health risk assessments for ingredients, materials, and finished products, with a focus on regulatory compliance and consumer safety. Author and manage the toxicology sections of regulatory submissions, ensuring scientific rigor, clarity, and completeness Direct the design, execution, and interpretation of toxicology studies, including in vitro and computational toxicology, often in collaboration with CROs. Evaluate and interpret toxicological data, including studies from scientific literature, to determine potential health impacts and support the development of scientific positions. Serve as a regulatory-facing subject matter expert, representing the company in FDA meetings, scientific conferences, and industry forums. Collaborate cross-functionally with product development, regulatory affairs, and legal teams to integrate toxicology data into broader regulatory strategies. Monitor evolving regulatory requirements, toxicological methodologies, and risk assessment frameworks to ensure proactive compliance and innovation. **Qualifications** - REQUIRED MINIMUM QUALIFICATIONS: Education: Ph.D. or Master's in Toxicology, Pharmacology, or a related life science field. Experience: Minimum of 7-10 years in human health risk assessment, with direct experience in FDA-regulated environments (preferably tobacco, pharmaceutical, or consumer products). Certification: Diplomate of the American Board of Toxicology (DABT) strongly preferred; candidates should be willing to obtain if not already certified. Certifications: Certifications such as Diplomate of the American Board of Toxicology (DABT). Candidates who do not currently hold these certifications should be willing to obtain them. In-depth knowledge of FDA regulatory pathways, especially PMTA and SE submissions. Proven ability to lead toxicological evaluations and regulatory strategy development. Experience with advanced toxicological testing methods, computational modeling, and statistical analysis. Strong communication skills, with the ability to present complex scientific concepts to regulatory bodies and non-scientific stakeholders. Proficiency in Microsoft Office and scientific data analysis tools. **Work Environment and Physical Demand** **What We Offer** - Competitive benefits package that includes medical/dental/vision/life insurance/disability plans - Dollar for dollar 401k match up to 6% and 5% annual company contribution - 15 Company-paid holidays - Generous paid time off - Employee recognition and discount programs - Education assistance - Employee referral bonus program - Hybrid workplace - remote / in office - Summer hours - Casual dress policy Monday through Friday **Applicant Information** This describes the essential functions of the job at the time the was created, but it is not an exhaustive list of tasks, duties and responsibilities. In addition, the position may evolve or change over time and such changes may not be reflected in the job description until it is next updated. **ITG Brands and ITG Cigars provides equal employment opportunities.** All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran. If you have a concern about discrimination in the application or hiring process or you need an accommodation based on religion, disability or pregnancy in the application or hiring process, please contact us at ******************************* . **SHARE THIS JOB** The posting for the position for which you are applying highlights key aspects of the position only. It is not a complete description of the position. All candidates must consent to an independent investigation of their background, references, past employment, education, criminal record, and drug screening. Results of such background checks will be reviewed on a case-by-case basis, giving consideration to the nature of the information reported and its relevance to the specific job being sought before a decision is made using this information. ITG Brands and ITG Cigars provides equal employment opportunities. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran. If you have a concern about discrimination in the application or hiring process or you need an accommodation based on religion, disability or pregnancy in the application or hiring process, please contact us at ******************************* (Talen%74Acquisition%40%69t%67b%72ands.%63om) . We collect personal information from you in connection with your application for employment with ITG Brands or ITG Cigars. For more information, please see our Privacy Policy (****************************************** . If you are a job applicant from California, additional information can be found on our California Applicant Privacy Notice (******************************************************* . If you have questions, contact us atprivacy@itgbrands.com (priv%61%63y@i%74gb%72ands.co%6D) .

The Joint School of Nanoscience and Nanoengineering (JSNN) at North Carolina Agricultural and Technical State University (NC A&T) invites applications for a full-time research scientist position. We are looking for a highly motivated and talented research scientist to join our team in the field of nanomaterials. This is a DoD-initiated multiple year project with extensive industry support. The applicants are expected to have a Ph.D. degree in Nanoscience/Nanoengineering, Materials Science/Engineering, Chemistry, or a related discipline from an accredited institution with solid background in nanomaterials and abundant experience in nanoparticle synthesis such as metal nanoparticles, co-shell nanoparticles, ceramic nanoparticles, and hybrid nanoparticles, as well as nanoparticle characterization and application. The research scientist will carry out research in the field of nanomaterials particularly nanoparticles including material design, synthesis, characterization, and application, publish peer-reviewed journal articles, write and submit research report and grant proposals, disseminate research results and foster research collaborations, mentor and train graduate and undergraduate students, as well as additional duties under the supervision of the PI. The research scientist will enjoy a dynamic and collaborative working environment. This is a renewable position subject to satisfactory performance and availability of funding. US citizenship or lawful permanent residency is required. Primary Function of Organizational Unit North Carolina Agricultural and Technical State University (NC A&T) is a public land grant doctoral university and a constituent member of the University of North Carolina (UNC) system with an enrollment of over 15,000 students. NC A&T is classified as "R2-High Research Activity" by the Carnegie Foundation and is poised to achieve "R1-Very High Research Activity" Status. The Joint School of Nanoscience and Nanoengineering (JSNN) is an academic collaboration between NC A&T and the University of North Carolina at Greensboro (UNCG). JSNN is a $56.3 million, 105,000 square foot state-of-the-art science and engineering education and research facility. JSNN builds on the strengths of the two universities to offer innovative and cross-disciplinary M.S. and Ph.D. graduate programs in the emerging areas of nanoscience and nanoengineering. JSNN partnered with Georgia Tech and was awarded a National Nanotechnology Coordinated Infrastructure (NNCI) grant titled "Southeastern Nanotechnology Infrastructure Corridor (SENIC) by the National Science Foundation. JSNN and SENIC have provided great opportunities to conduct competitive nanoengineering research at NC A&T. The Department of Nanoengineering is dedicated to educating the next generation of leaders in nanotechnology, advancing the understanding of nanoscale phenomena and applications, and serving society through education, outreach, and development of cutting-edge technologies. Committed to excellence in teaching, research, and community engagement, the department strives to achieve national distinction and preeminence in the field. Minimum Requirements (1) Ph.D. in Nanoscience/Nanoengineering, Materials Science/Engineering, Chemistry, or related discipline from an accredited institution. (2) Solid background in nanomaterials and abundant experience in nanoparticle synthesis. (3) Self-motivated and independent researcher. (4) Good communication skills. (5) Publication record. (6) Experience in mentoring students. Preferred Years Experience, Skills, Training, Education (1) Previous experience in nanoparticle synthesis such as metal nanoparticles, co-shell nanoparticles, ceramic nanoparticles, and hybrid nanoparticles, as well as nanoparticle characterization and application. (2) Proficiency in analytical tools like SEM, TEM, DSC, and other nanomaterial characterization techniques. (3) Excellent critical thinking, writing, communication, teamwork, and organization/management skills. Required License or Certification N/A Is this position eligible for a remote or hybrid work arrangement, consistent with university and state policies. On-site (Employees are primarily in the office and/or have a critical job requirement that requires dedicated office space on-site)

Reynolds American is evolving at pace into a global multi-category business. Our purpose is to create A Better Tomorrow by Building a Smokeless World. To achieve our ambition, we are looking for colleagues who are ready to join us on this journey! Tomorrow can't wait, let's shape it together! REYNOLDS AMERICAN has an exciting opportunity for a Senior Manager Real-World Evidence in Winston-Salem, NC. The Senior Scientist Real-World Evidence, will provide expertise in managing the planning, execution, monitoring, and closing of clinical research to support regulatory submissions and real-world experiences of our products. In this position, the individual will collaborate on projects and programs related to actual use observational studies to support regulatory submissions for current and future market products. Additionally, this position will contribute to generating scientific evidence to support tobacco harm reduction initiatives. This role will participate in cross-functional collaborations and build relationships with internal and external partners to influence regulatory science strategy and deliver evidence generation. Further, this role will bring ingenuity and creativity to independently develop and recommend solutions to complex problems. This person will deliver evidence generation while maintaining high scientific standards and integrity, and adhering to all applicable regulations and procedures. This position requires strong technical, project management, and communication skills. A strong background in observational and/or clinical research is desired. Your key responsabilities will include: * Significantly contribute to the operational planning and execution of clinical studies (e.g., actual use trials, pragmatic trials) for tobacco products intended for FDA regulatory submissions. * Act as the primary liaison between clinical research teams, vendors, and cross-functional stakeholders. * Develop and manage detailed project plans, timelines, budgets, and resource allocations. * Assist in the generation of scientific evidence to influence regulatory science strategy * Project management across multiple projects with internal and external stakeholders * Provide insight into scientific study design and data interpretation across a variety of social and behavioral scientific disciplines * Regulatory science engagement through publications, conference presentations, and external collaborations * Regulatory writing and scientific and regulatory engagement What are we looking for? * Advanced degree (Ph.D. or M.S.) in epidemiology, chemistry, biology, toxicology, pharmacology, clinical or social science, or other relevant discipline * 2+ years relevant scientific experience resulting in a thorough knowledge of concepts, principles and strategic relevance as pertains to conducting randomized controlled trials and observational research studies * Experience working in a regulated industry, such as tobacco/nicotine, pharmaceutical, and/or medical device * Demonstrated ability to manage and execute multiple projects * Strong organizational, writing, presentation, and communication skills, with the ability to interface with other functions within (and external to) the Company * Ability to conceive, plan and conduct work streams aligned with, and in support of, regulatory strategy * Strong ability to apply critical thinking to ambiguous or complex scientific challenges * Extensive experience navigating tobacco regulatory frameworks and proficiency in biostatistics or data interpretation is considered beneficial WE ARE REYNOLDS AMERICAN-A member of the BRITISH AMERICAN TOBACCO GROUP At Reynolds American, we are committed to our Purpose of creating A Better Tomorrow. This is what drives our people and our passion for innovation. See what is possible for you at REYNOLDS AMERICAN. BELONGING, ACHIEVING, TOGETHER Collaboration and teamwork underpin everything we do here at Reynolds American. We know that collaborating with colleagues is what makes us stronger and best prepared to meet our business goals. BENEFITS OVERVIEW Benefit Information The following is a general summary of the competitive compensation and benefit plans we offer: * 401(k) plan that offers opportunity to save on pre- and post-tax basis up to 50 percent of eligible compensation. o Company matches 100 percent of employee pre-tax/Roth (401k) contributions up to six percent o Company contributes an additional three percent to 401(k) whether employee participates or not * Comprehensive health- and welfare-benefits package (including medical, dental, vision, and prescription drugs) * Health Savings Account start-up contribution for employees who elect the high deductible health plan * Flexible spending accounts for both Health Care and Dependent Care allowing employee to use pre-tax dollars to pay for qualified expenses during the calendar year * Employee assistance program offering 8 free counselling sessions, per issue, each calendar year for employees and their dependents * Company paid life insurance of 1x annual base pay ($50,000 minimum) * Company paid accidental death or dismemberment insurance of 2x annual base pay ($50,000 minimum) * Voluntary insurances offered at group rates: employee and dependent life insurance, AD&D insurance, critical illness, accident coverage, disability buy-up, and auto & home insurance * Tuition reimbursement and student loan support * Dependent Scholarship Programs * Free confidential personal financial counselling service * On-site health centers and 24/7 fitness centers at certain company locations * A charitable giving matching grants program that enables employees to direct and double their donations to qualifying charitable organizations of their choice * Health-care concierge service * Volunteer service opportunities * Extensive training opportunities * Company vehicle for eligible employees * Mobile phone allowance for eligible employees * Paid Leave: o Sick and Personal Time (exempt employees may be excused with pay for brief absences; non-exempt employees receive up to 6 days) o Vacation (levels Below Senior Director receive 15 days (pro-rated during first year of service); Senior Director and Officers receive 25 days (pro-rated during first year of service)). o Holidays (Nine company recognized and two annual personal holidays to be used at the employee's discretion) o Paid Parental Leave + temporary reduced work schedule opportunity o Funeral Leave o Short-Term Disability Leave o Long-Term Disability Leave o Jury Duty Leave o Military Leave o Released Time for Children's Education o Community Outreach Leave o Other paid leave benefits, as required by state or local law * Your journey with us isn't limited by boundaries; it's propelled by your aspirations. Join us at Reynolds American and become a part of an environment that thrives on internal advancement, where your career progression isn't just a statement - it's a reality we're eager to build together. Seize the opportunity and own your development; your next chapter starts here. * You'll have access to online learning platforms and personalized growth programs to nurture your leadership skills * We prioritise continuous improvement within a transformative environment, preparing for ongoing changes Our organization offers a level of challenge, responsibility, and creativity for motivated employees who want to grow their careers. We are also committed to valuing different perspectives, experiences, and talents to improve the company's potential for optimally achieving its business objectives! Reynolds American Inc. and its affiliated companies is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to age, race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other status protected by law. Only applicants requiring reasonable accommodation for any part of the application and hiring process should contact us directly via email at *******************

is located in Winston-Salem, NC and it is onsite Monday thru Friday Title: Senior Food Scientist This role will be the resident expert for sauce, dips, and syrups using scientific principles to research, develop and improve current as well as new products. Position requires a person who is strong in practical and technical and analytical skills along with sauce development experience. This position is in a lab within a manufacturing facility. Primary Tasks: Independently leads medium to high complexity projects to deliver formulas that are cost-effective, processing optimized, and preferred by customers. Applies scientific principles to understand the chemical, physical, and sensory properties of food ingredients, ensuring safety and quality. Co-develops projects with key customers Leverages internal and external consultants along with preferred vendors to drive projects forward and deliver approved formulas within agreed upon timelines Supports Sales as representative of R&D during customer meetings/calls Documents formulas, feedback, and cutting notes ensure learnings are readily available Collects, records, analyzes, and presents data and recommendations during development and stability testing Reporting Structure: Reports to Director of Innovation Additional Responsibilities: Mentors junior team members Acts as on-site technical resource for Production and Quality Acts as backup for Director of Innovation Remains engaged in flavor, ingredient, and category trends to enable suggestion of new projects Qualifications & Skills: Bachelor's degree in food science, food technology, or food chemistry. Advanced degree is strongly preferred. At least 5 years of experience developing CPG products. Dressing and sauce R&D experience is strongly preferred. Strong understanding of principles of food science and ingredient functionality. Expertise in one food science discipline preferred. Intermediate computer skills (Word, Excel, Outlook, Teams, etc.) and willingness to learn new systems. Project management experience; working knowledge of stage gate, costing, and typical R&D workflows. Other: Ability to communicate technical information and research findings clearly and concisely both verbally and in writing Continuously curious, creative, eager to grow knowledge base Ability to adapt to unforeseen circumstances and view setbacks as learning Skilled at influencing without direct authority and championing ideas within a cross functional team Ability to direct and handle multiple tasks at one time and work within a project timeline. Ability to travel Willingness and ability to consume dressing and sauce products including nuts, soy, eggs, dairy, sesame, shellfish, wheat, and mustard. Ability to occasionally lift 40lbs Must be willing to work weekends, holidays, and varying shifts, as required.

is located in Winston-Salem, NC and it is onsite Monday thru Friday Title: Senior Food Scientist This role will be the resident expert for sauce, dips, and syrups using scientific principles to research, develop and improve current as well as new products. Position requires a person who is strong in practical and technical and analytical skills along with sauce development experience. This position is in a lab within a manufacturing facility. Primary Tasks: Independently leads medium to high complexity projects to deliver formulas that are cost-effective, processing optimized, and preferred by customers. Applies scientific principles to understand the chemical, physical, and sensory properties of food ingredients, ensuring safety and quality. Co-develops projects with key customers Leverages internal and external consultants along with preferred vendors to drive projects forward and deliver approved formulas within agreed upon timelines Supports Sales as representative of R&D during customer meetings/calls Documents formulas, feedback, and cutting notes ensure learnings are readily available Collects, records, analyzes, and presents data and recommendations during development and stability testing Reporting Structure: Reports to Director of Innovation Additional Responsibilities: Mentors junior team members Acts as on-site technical resource for Production and Quality Acts as backup for Director of Innovation Remains engaged in flavor, ingredient, and category trends to enable suggestion of new projects Qualifications & Skills: Bachelor's degree in food science, food technology, or food chemistry. Advanced degree is strongly preferred. At least 5 years of experience developing CPG products. Dressing and sauce R&D experience is strongly preferred. Strong understanding of principles of food science and ingredient functionality. Expertise in one food science discipline preferred. Intermediate computer skills (Word, Excel, Outlook, Teams, etc.) and willingness to learn new systems. Project management experience; working knowledge of stage gate, costing, and typical R&D workflows. Other: Ability to communicate technical information and research findings clearly and concisely both verbally and in writing Continuously curious, creative, eager to grow knowledge base Ability to adapt to unforeseen circumstances and view setbacks as learning Skilled at influencing without direct authority and championing ideas within a cross functional team Ability to direct and handle multiple tasks at one time and work within a project timeline. Ability to travel Willingness and ability to consume dressing and sauce products including nuts, soy, eggs, dairy, sesame, shellfish, wheat, and mustard. Ability to occasionally lift 40lbs Must be willing to work weekends, holidays, and varying shifts, as required.

Department: 85082 Wake Forest University Health Sciences - Academic Biomedical Engineering Status: Full time Benefits Eligible: Yes Hours Per Week: 40 Schedule Details/Additional Information: Varies The M-Sense Research Group within the new Center for Health Monitoring at Wake Forest University Health Sciences is seeking motivated and enthusiastic researchers to join our interdisciplinary team. In line with our mission of empowering patients with digital health technologies, researchers will contribute to ongoing, and dynamic research programs that are at the forefront of our field and are positioned for successful translation to market. Projects include efforts to develop digital biomarkers of balance and mobility impairment for use as novel endpoints in clinical trials or as a key component of digital therapeutics for fall prevention, to identify effective digital health strategies for helping adults of every age develop and sustain healthy behaviors, to detect the presence of mental health disorders in young children rapidly at the point of care, and to manage and prevent panic attacks wherever and whenever they occur. Researchers will also contribute to projects across the research enterprise leveraging digital health technologies and have access to funds to support the development of new research projects that leverage resources of the Center for Remote Patient and Participant Monitoring and the scale of theevolving integrated healthcare system, which is currently caring for more than seven million patients in Illinois, Georgia, Alabama, Wisconsin, and the Carolinas. Specific responsibilities will include software development and validation; development of signal processing and machine learning algorithms; data engineering; data analysis; data visualization; documentation; manuscript, grant proposal, and presentation development; student research mentorship; and reporting. Successful candidates will have a PhD or equivalent degree and experience working with data from wearable devices, developing and evaluating signal processing and machine learning algorithms, programming in python, and publishing scientific manuscripts. Pay Range $30.15 - $45.25 Our Commitment to You: Advocate Health offers a comprehensive suite of Total Rewards: benefits and well-being programs, competitive compensation, generous retirement offerings, programs that invest in your career development and so much more - so you can live fully at and away from work, including: Compensation * Base compensation listed within the listed pay range based on factors such as qualifications, skills, relevant experience, and/or training * Premium pay such as shift, on call, and more based on a teammate's job * Incentive pay for select positions * Opportunity for annual increases based on performance Benefits and more * Paid Time Off programs * Health and welfare benefits such as medical, dental, vision, life, and Short- and Long-Term Disability * Flexible Spending Accounts for eligible health care and dependent care expenses * Family benefits such as adoption assistance and paid parental leave * Defined contribution retirement plans with employer match and other financial wellness programs * Educational Assistance Program About Advocate Health Advocate Health is the third-largest nonprofit, integrated health system in the United States, created from the combination of Advocate Aurora Health and Atrium Health. Providing care under the names Advocate Health Care in Illinois; Atrium Health in the Carolinas, Georgia and Alabama; and Aurora Health Care in Wisconsin, Advocate Health is a national leader in clinical innovation, health outcomes, consumer experience and value-based care. Headquartered in Charlotte, North Carolina, Advocate Health services nearly 6 million patients and is engaged in hundreds of clinical trials and research studies, with Wake Forest University School of Medicine serving as the academic core of the enterprise. It is nationally recognized for its expertise in cardiology, neurosciences, oncology, pediatrics and rehabilitation, as well as organ transplants, burn treatments and specialized musculoskeletal programs. Advocate Health employs 155,000 teammates across 69 hospitals and over 1,000 care locations, and offers one of the nation's largest graduate medical education programs with over 2,000 residents and fellows across more than 200 programs. Committed to providing equitable care for all, Advocate Health provides more than $6 billion in annual community benefits.

Department: 85107 Wake Forest University Health Sciences - Academic WF Institute for Regen Medicine Status: Full time Benefits Eligible: Yes Hours Per Week: 40 Schedule Details/Additional Information: 1st shift Pay Range $30.15 - $45.25 Postdoctoral Position Available Wake Forest Institute for Regenerative Medicine Winston-Salem, NC, USA We are inviting applications for a postdoctoral research position supported by a funded Department of Defense (DoD) grant. This opportunity is ideal for a highly motivated and skilled researcher interested in advancing translational science in the fields of stem cell biology, regenerative medicine, and cancer therapeutics. Position Overview The successful candidate will contribute to a multidisciplinary research program focused on developing novel therapeutic strategies using stem cell-derived exosomes and biomaterials. The research involves both in vitro and in vivo studies, with a strong emphasis on mechanistic exploration and functional outcomes. Key Responsibilities Isolation and culture of human primary stem cells Transfection using mRNA and plasmid vectors Exosome isolation and molecular characterization Surgical procedures in animal models Administration of treatments targeting the lower urinary tract Functional assessments of urethral and bladder activity Molecular and histological analyses, including Western blotting, qPCR, immunostaining, and tissue histology Data collection and interpretation, including behavioral observations, in vivo imaging, and histopathological evaluation We welcome applicants with a strong background in biomedical sciences, molecular biology, or related fields. Prior experience with animal models and regenerative medicine techniques is highly desirable. PhD required. Our Commitment to You: Advocate Health offers a comprehensive suite of Total Rewards: benefits and well-being programs, competitive compensation, generous retirement offerings, programs that invest in your career development and so much more - so you can live fully at and away from work, including: Compensation Base compensation listed within the listed pay range based on factors such as qualifications, skills, relevant experience, and/or training Premium pay such as shift, on call, and more based on a teammate's job Incentive pay for select positions Opportunity for annual increases based on performance Benefits and more Paid Time Off programs Health and welfare benefits such as medical, dental, vision, life, and Short- and Long-Term Disability Flexible Spending Accounts for eligible health care and dependent care expenses Family benefits such as adoption assistance and paid parental leave Defined contribution retirement plans with employer match and other financial wellness programs Educational Assistance Program About Advocate Health Advocate Health is the third-largest nonprofit, integrated health system in the United States, created from the combination of Advocate Aurora Health and Atrium Health. Providing care under the names Advocate Health Care in Illinois; Atrium Health in the Carolinas, Georgia and Alabama; and Aurora Health Care in Wisconsin, Advocate Health is a national leader in clinical innovation, health outcomes, consumer experience and value-based care. Headquartered in Charlotte, North Carolina, Advocate Health services nearly 6 million patients and is engaged in hundreds of clinical trials and research studies, with Wake Forest University School of Medicine serving as the academic core of the enterprise. It is nationally recognized for its expertise in cardiology, neurosciences, oncology, pediatrics and rehabilitation, as well as organ transplants, burn treatments and specialized musculoskeletal programs. Advocate Health employs 155,000 teammates across 69 hospitals and over 1,000 care locations, and offers one of the nation's largest graduate medical education programs with over 2,000 residents and fellows across more than 200 programs. Committed to providing equitable care for all, Advocate Health provides more than $6 billion in annual community benefits.

Back to Search Results Research Fellow, Biochemistry Winston Salem, NC, United States Shift: Various Job Type: Regular Share: mail

A global higher education leader in innovative teaching, research and public service, the University of North Carolina at Chapel Hill consistently ranks as one of the nation's top public universities. Known for its beautiful campus, world-class medical care, commitment to the arts and top athletic programs, Carolina is an ideal place to teach, work and learn. One of the best college towns and best places to live in the United States, Chapel Hill has diverse social, cultural, recreation and professional opportunities that span the campus and community. University employees can choose from a wide range of professional training opportunities for career growth, skill development and lifelong learning and enjoy exclusive perks for numerous retail, restaurant and performing arts discounts, savings on local child care centers and special rates on select campus events. UNC-Chapel Hill offers full-time employees a comprehensive benefits package, paid leave, and a variety of health, life and retirement plans and additional programs that support a healthy work/life balance. Primary Purpose of Organizational Unit Our mission is to improve the health and well-being of North Carolinians and others whom we serve. We accomplish this by providing leadership and excellence in the interrelated areas of patient care, education and research. Patient care: We promote health and provide superb clinical care while maintaining our strong tradition of reaching underserved populations and reducing health disparities across North Carolina and beyond. Education: We prepare tomorrow`s healthcare professionals and biomedical researchers from all backgrounds by facilitating learning within innovative and integrated curricula and team-oriented interprofessional education to ensure a highly skilled workforce. Research: We develop and support a rich array of outstanding health sciences research programs, centers and resources. We provide infrastructure and opportunities for collaboration among disciplines throughout and beyond our university to support outstanding research. We foster programs in the areas of basic, translational, mechanistic and population research. Position Summary Dr. Samir Kelada's Laboratory in the Department of Genetics in the UNC School of Medicine is seeking a Research Scientist position.The Kelada Lab's research is aimed at identifying gene-environment interactions with air pollution exposure that affect the development and progression of respiratory diseases. The primary purpose of this new position is to design, execute and analyze experiments using mouse models of air pollution-induced respiratory disease, with a focus on identifying genetic and genomic predictors of adverse responses. Working with the Supervisor and other the lab members, the research scientist will oversee large-scale projects that involve measuring pulmonary and immune responses to air pollution across inbred strains of mice, using a variety of measurement approaches including flow cytometry, and isolating specific cell types of interest by flow sorting for subsequent analysis of gene expression and potentially epigenomic endpoints (e.g., chromatin accessibility). Thereafter, the research scientist will carry out both basic and complex statistical analyses of the data, including characterizing the effect of air pollution exposure on pulmonary and immune responses, analysis of differential gene expression in specific cell types, and in some cases carry out spatial transcriptomic analyses of specific lung regions. Finally, the research scientist will conduct quantitative genetic analysis (i.e., QTL mapping) of specific endpoints measured in mouse experimental crosses. In addition to carrying out these research projects, the research scientist will also be expected to lead efforts to present the results of these projects in lab meetings and conferences. Thus, strong scientific communication skills are fundamental for this position. Minimum Education and Experience Requirements Relevant post-Baccalaureate degree required (or foreign degree equivalent); for candidates demonstrating comparable independent research productivity, will accept a relevant Bachelor's degree (or foreign degree equivalent) and 3 or more years of relevant experience in substitution. May require terminal degree and licensure. Required Qualifications, Competencies, and Experience Post-doctoral fellowship in a related field and/or experience in other industry or government setting. Preferred Qualifications, Competencies, and Experience PhD in genetics/molecular biology or toxicology/environmental health. Experience with mouse models of environmentally-induced pulmonary disease, including phenotyping using bronchoalveolar lavage and tissue collection Flow cytometry and FACS sorting of cellular populations isolated from the murine lung and other organs. Demonstrated proficiency with standard statistical approaches for biomedical data using R software Demonstrated proficiency in analysis of bulk RNA-seq data using R software, including visualization approaches Proficiency with design spatial transcriptomics experiments and resulting data analysis Experience with quantitative trait locus mapping methods in experimental crosses Experience in giving scientific presentations Special Physical/Mental Requirements The candidate will be required to perform lab tasks and procedures that involve physical dexterity. The applicant must be willing to work with and handle mice, including performing dissections. Campus Security Authority Responsibilities Not Applicable. 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THIS POSTING IS FOR TWO IDENTICAL POSITIONS ( POSITION NUMBERS 20071670 & 20071671). BY APPLYING TO THIS POSTING , YOU WILL BE CONSIDERED FOR BOTH AVAILABLE POSITIONS . The University of North Carolina at Chapel Hill is seeking a Research Scientist to direct, perform and attract funding for research in its Institute for Risk Management and Insurance Innovation ( IRMII ). This research involves a unique set of skills and expertise to be used in developing computational models that characterize and manage financial risk across a wide range of contexts, from flooding to pandemics to cyberattacks. This includes knowledge of engineering, data science and domain specific expertise in at least one additional area related to financial risk (e.g., environment, public health). Outcomes from this research involve (1) quantification of financial risk through the linking of models that characterize natural, engineered/managed and economic systems, and (2) the subsequent development of novel tools and strategies for managing financial risk. The successful candidate will engage in the development of interdisciplinary computational models that link natural, engineered/managed and economic systems for the purpose of quantifying financial risk, and then develop tools and strategies for managing that risk. Model development will include detailed computational renderings of these coupled systems in a stochastic simulation environment. These projects will span a range of regions (e.g., California, U.S. Pacific Northwest, U.S. Southeast, Africa) and a number of different economic sectors (e.g., power utilities, water utilities, agriculture, real estate, health care facilities), requiring an understanding of the financial linkages in these sectors, as well as the modeling skills to represent them accurately. In addition to model development, this individual will undertake to train graduate students and post-doctoral researchers in the conduct of this research and oversee their modeling efforts, then assist in the drafting of manuscripts, reports and oral presentations detailing the research. The successful candidate will be responsible for managing research personnel, including graduate students and post-doctoral associates to ensure that project milestones are met, project reports are completed and all requirements of the funders are fulfilled on time and in a satisfactory manner. The individual may also play a central role in coordinating activities with industry partners and/or multiple PIs in large interdisciplinary studies, ensuring that each member of a research team remains connected and coordinated. Other duties will include overseeing the collection, organization and storage of project data in appropriate repositories; monitoring of data sharing/data use agreements with partner organizations, and; coordinating multi-institutional modeling efforts by facilitating intra-team communication and the use of appropriate model sharing platforms (e.g. Github). The successful candidate will be responsible for assisting with, and in some cases leading, the conception, writing and preparation of new proposals to state and federal funding agencies, as well as other groups for the purpose of securing research funds. This will include not only the development of the research hypotheses and proposal framing, but budget development, inter-institutional partnership arrangements and coordination with both the Institute's operations manager and the University's Office of Sponsored Research. This individual will also be involved in communications with the funders, including response to reviewers, budget revisions and the preparation of annual reports. Required Qualifications, Competencies, And Experience The successful candidate must have experience in computational modeling that includes elements of engineering, natural science, economics and finance. Experience must also extend to developing interdisciplinary models that incorporate principles from each of these areas into a cohesive whole that enables the characterization of financial risk and subsequent strategies for managing this risk. Computational modeling skills are critical, as is fluency in one or more programming languages (e.g., Python, R, C++). The individual should have the ability to foster partnerships across diverse areas of research expertise and the ability to facilitate collaboration with other institutions, industry partners, and funding agencies. The individual should also have experience in manuscript writing. Preferred Qualifications, Competencies, And Experience At least 3 years of relevant experience is preferred. Research experience that would support the case for an eventual appointment as a research or adjunct faculty member at some future point would be a plus.

Reynolds American is evolving at pace into a global multi-category business. Our purpose is to create A Better Tomorrow™ by Building a Smokeless World. To achieve our ambition, we are looking for colleagues who are ready to join us on this journey! Tomorrow can't wait, let's shape it together! REYNOLDS AMERICAN has an exciting opportunity for a Senior Manager Real-World Evidence in Winston-Salem, NC. The Senior Scientist Real-World Evidence, will provide expertise in managing the planning, execution, monitoring, and closing of clinical research to support regulatory submissions and real-world experiences of our products. In this position, the individual will collaborate on projects and programs related to actual use observational studies to support regulatory submissions for current and future market products. Additionally, this position will contribute to generating scientific evidence to support tobacco harm reduction initiatives. This role will participate in cross-functional collaborations and build relationships with internal and external partners to influence regulatory science strategy and deliver evidence generation. Further, this role will bring ingenuity and creativity to independently develop and recommend solutions to complex problems. This person will deliver evidence generation while maintaining high scientific standards and integrity, and adhering to all applicable regulations and procedures. This position requires strong technical, project management, and communication skills. A strong background in observational and/or clinical research is desired. Your key responsabilities will include: Significantly contribute to the operational planning and execution of clinical studies (e.g., actual use trials, pragmatic trials) for tobacco products intended for FDA regulatory submissions. Act as the primary liaison between clinical research teams, vendors, and cross-functional stakeholders. Develop and manage detailed project plans, timelines, budgets, and resource allocations. Assist in the generation of scientific evidence to influence regulatory science strategy Project management across multiple projects with internal and external stakeholders Provide insight into scientific study design and data interpretation across a variety of social and behavioral scientific disciplines Regulatory science engagement through publications, conference presentations, and external collaborations Regulatory writing and scientific and regulatory engagement What are we looking for? Advanced degree (Ph.D. or M.S.) in epidemiology, chemistry, biology, toxicology, pharmacology, clinical or social science, or other relevant discipline 2+ years relevant scientific experience resulting in a thorough knowledge of concepts, principles and strategic relevance as pertains to conducting randomized controlled trials and observational research studies Experience working in a regulated industry, such as tobacco/nicotine, pharmaceutical, and/or medical device Demonstrated ability to manage and execute multiple projects Strong organizational, writing, presentation, and communication skills, with the ability to interface with other functions within (and external to) the Company Ability to conceive, plan and conduct work streams aligned with, and in support of, regulatory strategy Strong ability to apply critical thinking to ambiguous or complex scientific challenges Extensive experience navigating tobacco regulatory frameworks and proficiency in biostatistics or data interpretation is considered beneficial WE ARE REYNOLDS AMERICAN-A member of the BRITISH AMERICAN TOBACCO GROUP At Reynolds American, we are committed to our Purpose of creating A Better Tomorrow. This is what drives our people and our passion for innovation. See what is possible for you at REYNOLDS AMERICAN. BELONGING, ACHIEVING, TOGETHER Collaboration and teamwork underpin everything we do here at Reynolds American. We know that collaborating with colleagues is what makes us stronger and best prepared to meet our business goals. BENEFITS OVERVIEW Benefit Information The following is a general summary of the competitive compensation and benefit plans we offer: • 401(k) plan that offers opportunity to save on pre- and post-tax basis up to 50 percent of eligible compensation. o Company matches 100 percent of employee pre-tax/Roth (401k) contributions up to six percent o Company contributes an additional three percent to 401(k) whether employee participates or not • Comprehensive health- and welfare-benefits package (including medical, dental, vision, and prescription drugs) • Health Savings Account start-up contribution for employees who elect the high deductible health plan • Flexible spending accounts for both Health Care and Dependent Care allowing employee to use pre-tax dollars to pay for qualified expenses during the calendar year • Employee assistance program offering 8 free counselling sessions, per issue, each calendar year for employees and their dependents • Company paid life insurance of 1x annual base pay ($50,000 minimum) • Company paid accidental death or dismemberment insurance of 2x annual base pay ($50,000 minimum) • Voluntary insurances offered at group rates: employee and dependent life insurance, AD&D insurance, critical illness, accident coverage, disability buy-up, and auto & home insurance • Tuition reimbursement and student loan support • Dependent Scholarship Programs • Free confidential personal financial counselling service • On-site health centers and 24/7 fitness centers at certain company locations • A charitable giving matching grants program that enables employees to direct and double their donations to qualifying charitable organizations of their choice • Health-care concierge service • Volunteer service opportunities • Extensive training opportunities • Company vehicle for eligible employees • Mobile phone allowance for eligible employees • Paid Leave: o Sick and Personal Time (exempt employees may be excused with pay for brief absences; non-exempt employees receive up to 6 days) o Vacation (levels Below Senior Director receive 15 days (pro-rated during first year of service); Senior Director and Officers receive 25 days (pro-rated during first year of service)). o Holidays (Nine company recognized and two annual personal holidays to be used at the employee's discretion) o Paid Parental Leave + temporary reduced work schedule opportunity o Funeral Leave o Short-Term Disability Leave o Long-Term Disability Leave o Jury Duty Leave o Military Leave o Released Time for Children's Education o Community Outreach Leave o Other paid leave benefits, as required by state or local law • Your journey with us isn't limited by boundaries; it's propelled by your aspirations. Join us at Reynolds American and become a part of an environment that thrives on internal advancement, where your career progression isn't just a statement - it's a reality we're eager to build together. Seize the opportunity and own your development; your next chapter starts here. • You'll have access to online learning platforms and personalized growth programs to nurture your leadership skills • We prioritise continuous improvement within a transformative environment, preparing for ongoing changes Our organization offers a level of challenge, responsibility, and creativity for motivated employees who want to grow their careers. We are also committed to valuing different perspectives, experiences, and talents to improve the company's potential for optimally achieving its business objectives! Reynolds American Inc. and its affiliated companies is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to age, race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other status protected by law. Only applicants requiring reasonable accommodation for any part of the application and hiring process should contact us directly via email at *******************

Department: 85107 Wake Forest University Health Sciences - Academic WF Institute for Regen Medicine Status: Full time Benefits Eligible: Yes Hours Per Week: 40 Schedule Details/Additional Information: Varies Pay Range $30.15 - $45.25 The WFIRM Postdoctoral Research Fellow will participate in a research project to develop a new platform to enable the testing of vaccines. The applicant will perform a variety of complex tasks including antigen uptake and presentation, immune cell activation and differentiation, in vitrobiological and functional tests for verification of tissue construct viability and functional assays. Research will be performed in a team environment and the application will be provided with a variety of procedures and techniques previously outlined by established protocols and other scientific data related to the production of tissue engineered constructs. Specific duties will include basic and advanced immunological protocols including antigen presentation, T and B cell activation, cell culture and expansion, assembly of 3D constructs using biofabrication techniques, collection and organization of data, and assisting in the preparation of reports and manuscripts. Immunology, engineering, and cell biology experience is a plus. EDUCATION/EXPERIENCE Ph.D. with a focus in biological, immunological, engineering or biomedical engineering. SKILLS & QUALIFICATIONS * Experience in cell culture and immunology techniques. * Experience in antigen presentation, T cell and B cell activation and differentiation * Experience with development and testing of tissue engineering constructs * Experience in biofabrication and tissue engineering technologies such as bioprinting, for creation of tissue engineered constructs. * Bioengineering, Biomedical Engineering, or Materials Science background a plus. * General computer skills, including the use of Excel spreadsheets * Attention to detail * Excellent organizational skills * Time management * Excellent recordkeeping and documentation skills WORK ENVIRONMENT The Wake Forest Institute for Regenerative Medicine (WFIRM) is a world leader in the development of technologies and products in the fields of tissue engineering and regenerative medicine. WFIRM is an interdisciplinary institute, with a semi-open laboratory concept aimed towards fostering collaboration in a variety of research areas. WFIRM occupies several floors in the Richard H. Dean Biomedical Building in the Wake Forest Innovation Quarter in Winston-Salem. Our Commitment to You: Advocate Health offers a comprehensive suite of Total Rewards: benefits and well-being programs, competitive compensation, generous retirement offerings, programs that invest in your career development and so much more - so you can live fully at and away from work, including: Compensation * Base compensation listed within the listed pay range based on factors such as qualifications, skills, relevant experience, and/or training * Premium pay such as shift, on call, and more based on a teammate's job * Incentive pay for select positions * Opportunity for annual increases based on performance Benefits and more * Paid Time Off programs * Health and welfare benefits such as medical, dental, vision, life, and Short- and Long-Term Disability * Flexible Spending Accounts for eligible health care and dependent care expenses * Family benefits such as adoption assistance and paid parental leave * Defined contribution retirement plans with employer match and other financial wellness programs * Educational Assistance Program About Advocate Health Advocate Health is the third-largest nonprofit, integrated health system in the United States, created from the combination of Advocate Aurora Health and Atrium Health. Providing care under the names Advocate Health Care in Illinois; Atrium Health in the Carolinas, Georgia and Alabama; and Aurora Health Care in Wisconsin, Advocate Health is a national leader in clinical innovation, health outcomes, consumer experience and value-based care. Headquartered in Charlotte, North Carolina, Advocate Health services nearly 6 million patients and is engaged in hundreds of clinical trials and research studies, with Wake Forest University School of Medicine serving as the academic core of the enterprise. It is nationally recognized for its expertise in cardiology, neurosciences, oncology, pediatrics and rehabilitation, as well as organ transplants, burn treatments and specialized musculoskeletal programs. Advocate Health employs 155,000 teammates across 69 hospitals and over 1,000 care locations, and offers one of the nation's largest graduate medical education programs with over 2,000 residents and fellows across more than 200 programs. Committed to providing equitable care for all, Advocate Health provides more than $6 billion in annual community benefits.