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  • Principal Applied Scientist

    Viant 4.3company rating

    Principal research scientist job in Irvine, CA

    WHAT YOU'LL DO Viant's Machine Learning team is at the forefront of transforming the Ad Tech industry through cutting-edge machine learning and AI-driven automation. By eliminating manual processes in digital ad creation, optimization, and measurement, we build autonomous, scalable systems that process hundreds of millions of events daily. We are seeking an exceptional Principal Applied Scientist to drive groundbreaking innovation in applied machine learning. In this role, you will lead end-to-end AI strategy, shape the applied science roadmap, and develop next-generation models in NLP, deep learning, and large-scale AI systems. Your expertise will push the boundaries of AI capabilities, delivering measurable business impact while fostering a research-driven, data-centric culture at Viant. THE DAY-TO-DAY * Lead and Define AI Strategy - Set the vision for applied ML research and AI-driven decision-making across Viant's products and services. * Drive High-Impact Research - Conduct advanced research in NLP, RL, LLMs, and deep learning, publishing in top-tier conferences while applying findings to real-world production systems. * Architect and Deploy ML at Scale - Develop, optimize, and deploy high-throughput, low-latency ML models, collaborating with engineers to bring solutions into production. * Innovate in Generative AI & Causal ML - Explore novel AI techniques, such as LLMs, reinforcement learning, and causal inference, to enhance targeting, personalization, and attribution models. * Experimentation and Validation - Design, run, and analyze A/B experiments to test ML-driven strategies, ensuring data-driven decision-making. * Mentor and Influence - Provide technical leadership for a team of applied scientists and ML engineers, fostering a culture of innovation and excellence. MUST HAVE * Experience: 7+ years of experience building and deploying machine learning models at scale. * Technical Leadership: Demonstrated ability to lead complex, high-ambiguity ML projects from research to production. * Academic & Industry Recognition: Masters + At least two peer-reviewed publications in deep learning, NLP, or a related AI domain or a PhD in Computer Science, Machine Learning, Statistics, or a related quantitative field. * Deep Expertise in ML & AI: Strong foundation in deep learning, NLP, generative AI, and causal inference. * Programming & Frameworks: Proficiency in Python and deep learning frameworks (TensorFlow, PyTorch, LangChain, Llama Index). * Scalability & Cloud: Experience with distributed computing, cloud ML platforms (AWS, GCP, or Azure), and real-time AI inference. GREAT TO HAVE * Industry Impact: Publications at top-tier ML/NLP conferences (NeurIPS, ICML, ICLR, ACL, EMNLP, NAACL, AAAI). * Ad Tech Expertise: Experience in digital advertising, real-time bidding, or audience modeling. * Generative AI Applications: Hands-on experience with LLMs and multimodal AI applications. * Optimization & Personalization: Strong background in reinforcement learning, dynamic pricing, or recommendation systems. LIFE AT VIANT Investing in our employee's professional growth is important to us, but so is investing in their well-being. That's why Viant was voted one of the best places to work and some of our favorite employee benefits include fully paid health insurance, paid parental leave and unlimited PTO and more. Base compensation range: $220,000 - $260,000 In accordance with California law, the range provided is Viant's reasonable estimate of the compensation for this role. Final title and compensation for the position will be based on several factors including work experience and education. #LI-KW1 About Viant Viant Technology Inc. (NASDAQ: DSP) is a leader in CTV and AI-powered programmatic advertising, dedicated to driving innovation in digital marketing. Viant's omnichannel platform built for CTV allows marketers to plan, execute and measure their campaigns with unmatched precision and efficiency. With the launch of ViantAI, Viant is building the future of fully autonomous advertising solutions, empowering advertisers to achieve their boldest goals. Viant was recently awarded Best AI-Powered Advertising Solution and Best Demand-Side Platform by MarTech Breakthrough, Great Place to Work certification and received the Business Intelligence Group's AI Excellence Award. Learn more at viantinc.com. Viant is an equal opportunity employer and makes employment decisions on the basis of merit. Viant prohibits unlawful discrimination against employees or applicants based on race (including traits historically associated with race, such as hair texture and protective hairstyles), religion, religious creed, color, national origin, ancestry, physical disability, mental disability, medical condition, genetic information, marital status, sex, reproductive health decision making, gender, gender identity, gender expression, age, military status, veteran status, uniformed service member status, sexual orientation, transgender identity, citizenship status, pregnancy, or any other consideration made unlawful by federal, state, or local laws. Viant also prohibits unlawful discrimination based on the perception that anyone has any of those characteristics, or is associated with a person who has or is perceived as having any of those characteristics. By clicking "Apply for this Job" and providing any information, I accept the Viant California Personnel Privacy Notice.
    $220k-260k yearly 60d+ ago
  • Principal Control Systems Scientist (R&D) / Medical Device

    Rennickbarrett Recruiting

    Principal research scientist job in Irvine, CA

    Role Summary: Defining the Future of Closed-Loop Medical Technology We are seeking a Principal Control Systems Scientist to drive the strategic development of advanced, life-saving control algorithms within our R&D organization. This is a top-tier individual contributor role requiring a recognized expert in control theory, applied mathematics, and human physiology to pioneer the next generation of intelligent, closed-loop medical devices. The Principal Scientist will serve as the technical authority for complex control systems, directly influencing product architecture to ensure optimal precision, safety, and real-time responsiveness in critical care and drug delivery technologies. This role moves beyond standard engineering to focus on scientific modeling, hypothesis generation, and the mathematical rigor required for FDA-regulated systems. Principal Roles and Scientific Leadership The Principal Control Systems Scientist will be responsible for setting the scientific direction and ensuring the technical integrity of all control algorithms. Key responsibilities include: Scientific Leadership & Strategy: Act as the subject matter expert and technical lead for all closed-loop control system design within the R&D portfolio. Define the long-term algorithm roadmap and guide the research team on emergent control technologies. Advanced Model Development: Design, formulate, and validate complex mathematical and simulation models (MATLAB/Simulink) of human physiological systems (e.g., cardiovascular hemodynamics, pharmacokinetics/pharmacodynamics) to serve as the foundation for new control strategies. Algorithm Innovation: Lead the development and implementation of advanced control algorithms, including Model Predictive Control (MPC), adaptive control, and robust control strategies, to achieve precision automation in medical devices. Physiological Data Analysis: Apply advanced signal processing and statistical methods to analyze complex physiological waveforms and sensor data, translating raw measurements into actionable control parameters. Clinical and Feasibility Research: Design and lead the scientific execution of in-vitro, animal, and clinical feasibility studies to collect data, validate physiological models, and characterize algorithm performance under real-world conditions. Regulatory & Safety Rigor: Ensure all scientific models and algorithm designs meet the stringent requirements of FDA design controls and relevant safety standards (e.g., IEC 62304). Provide critical technical documentation and subject matter expertise for regulatory submissions. Technical Mentorship: Provide expert guidance and mentorship to other R&D engineers and scientists, promoting a culture of rigor, best practices, and innovation in control systems. Required Qualifications and Scientific Experience This is a senior scientific role requiring significant depth of knowledge and proven leadership in regulated environments. Education: PhD in Control Systems Engineering, Biomedical Engineering, Applied Mathematics, or a related scientific field is highly preferred, with a minimum of 8 years of relevant experience. Alternative: Master's degree with a minimum of 11 years of experience, or a Bachelor's degree with a minimum of 12 years of experience. Core Expertise: Expert recognition in control engineering principles, system identification, and system dynamics, specifically applied to biological or physiological systems. Expert-level proficiency in designing, optimizing, and validating highly complex, real-time control algorithms. Deep expertise in mathematical modeling, signal processing, and algorithm development in MATLAB/Simulink. Medical Device Focus: Extensive experience with the modeling of pharmacokinetics and dynamics of common drugs. Strong background in human physiology and anatomy, with specific experience modeling or controlling cardiovascular hemodynamics and vital sign parameters. Direct experience with the design and implementation of physiologic closed-loop controlled medical devices (e.g., infusion pumps, ventilators). Implementation Skills: Proficiency in implementing and integrating control algorithms using C/C++ for embedded, real-time systems. Regulatory Knowledge: In-depth knowledge of FDA design controls and the software lifecycle processes required for medical device development. Preferred Scientific Qualifications Experience applying Machine Learning or AI techniques to adaptive control systems or predictive modeling of physiological states. Experience leading cross-functional research teams through the full development lifecycle, from concept and modeling to clinical V&V.
    $116k-179k yearly est. 60d+ ago
  • Senior Applied AI Scientist

    Cisco Systems, Inc. 4.8company rating

    Principal research scientist job in Irvine, CA

    Meet the Team Splunk, a Cisco company, is building a safer, more resilient digital world with an end‑to‑end, full‑stack platform designed for hybrid, multi‑cloud environments. Join the Foundational Modeling team at Splunk, where we advance the state of AI for high‑volume, real‑time, multi‑modal machine‑generated data - including logs, time series, traces, and events. We combine deep AI research expertise with the scale and operational excellence of Splunk and Cisco's global engineering capabilities. Our work spans networking, security, observability, and customer experience - designing and deploying foundation models that enhance reliability, strengthen security, prevent downtime, and deliver predictive insights across Splunk Observability, Security, and Platform at enterprise scale. You'll be part of a culture that values technical excellence, impact‑driven innovation, and cross‑functional collaboration - all within a flexible, growth‑oriented environment. Your Impact * Lead the research, design, and deployment of large‑scale foundation models for machine‑generated data - primarily time series, augmented with logs traces, and events. * Optimize distributed training and inference pipelines to maximize accuracy, performance, and efficiency at scale. * Work closely with engineering, product, and data science to ensure solutions meet defined technical requirements and deliver tangible business impact. * Mentor team members and contribute directly to model architecture reviews, experimental design, and production rollout processes. * Stay current with AI/ML developments and integrate relevant advancements into ongoing projects and technical plans. Minimum Qualifications: * PhD in Computer Science, or related quantitative field, plus 1+ years of industry research experience. * Proven track record in at least one of the following areas: large language modeling for both structure and unstructured data, deep learning‑based time series modeling, advanced anomaly detection, and multi-modality modeling. * Solid proficiency in Python and deep learning frameworks (e.g., PyTorch, TensorFlow) * Experience translating research ideas into production systems. Preferred Qualifications: * Deep Learning for Time Series & Forecasting - Proven expertise designing and deploying architectures such as temporal transformers, temporal convolutional networks, and spatial‑temporal models. * Advanced Anomaly Detection - Experience creating robust, scalable approaches (statistical, deep learning, or hybrid) for high‑volume, real‑time time series data. * Multi‑Modal AI Modeling - Strong track record fusing logs, time series, traces, tabular data, and graphs for foundation models tackling complex operational insights. * Probabilistic Forecasting & Uncertainty Quantification - Skills in Bayesian deep learning and probabilistic models to capture and communicate predictive uncertainty. * Large‑Scale Training & Optimization - Experience optimizing model architectures, distributed training pipelines, and inference efficiency to minimize cost and latency while preserving accuracy. * MLOps & Continuous Learning - Fluency in automated retraining, drift detection, incremental updates, and production monitoring of ML models. * Strong Research Track Record - Publications in top AI/ML conferences or journals (e.g., NeurIPS, ICML, ICLR, AAAI, CVPR, ACL, KDD) demonstrating contributions to state‑of‑the‑art methods and real‑world applications. Why Cisco? At Cisco, we're revolutionizing how data and infrastructure connect and protect organizations in the AI era - and beyond. We've been innovating fearlessly for 40 years to create solutions that power how humans and technology work together across the physical and digital worlds. These solutions provide customers with unparalleled security, visibility, and insights across the entire digital footprint. Fueled by the depth and breadth of our technology, we experiment and create meaningful solutions. Add to that our worldwide network of doers and experts, and you'll see that the opportunities to grow and build are limitless. We work as a team, collaborating with empathy to make really big things happen on a global scale. Because our solutions are everywhere, our impact is everywhere. We are Cisco, and our power starts with you. Message to applicants applying to work in the U.S. and/or Canada: The starting salary range posted for this position is $174,500.00 to $226,500.00 and reflects the projected salary range for new hires in this position in U.S. and/or Canada locations, not including incentive compensation*, equity, or benefits. Individual pay is determined by the candidate's hiring location, market conditions, job-related skillset, experience, qualifications, education, certifications, and/or training. The full salary range for certain locations is listed below. For locations not listed below, the recruiter can share more details about compensation for the role in your location during the hiring process. U.S. employees are offered benefits, subject to Cisco's plan eligibility rules, which include medical, dental and vision insurance, a 401(k) plan with a Cisco matching contribution, paid parental leave, short and long-term disability coverage, and basic life insurance. Please see the Cisco careers site to discover more benefits and perks. Employees may be eligible to receive grants of Cisco restricted stock units, which vest following continued employment with Cisco for defined periods of time. U.S. employees are eligible for paid time away as described below, subject to Cisco's policies: * 10 paid holidays per full calendar year, plus 1 floating holiday for non-exempt employees * 1 paid day off for employee's birthday, paid year-end holiday shutdown, and 4 paid days off for personal wellness determined by Cisco * Non-exempt employees receive 16 days of paid vacation time per full calendar year, accrued at rate of 4.92 hours per pay period for full-time employees * Exempt employees participate in Cisco's flexible vacation time off program, which has no defined limit on how much vacation time eligible employees may use (subject to availability and some business limitations) * 80 hours of sick time off provided on hire date and each January 1st thereafter, and up to 80 hours of unused sick time carried forward from one calendar year to the next * Additional paid time away may be requested to deal with critical or emergency issues for family members * Optional 10 paid days per full calendar year to volunteer For non-sales roles, employees are also eligible to earn annual bonuses subject to Cisco's policies. Employees on sales plans earn performance-based incentive pay on top of their base salary, which is split between quota and non-quota components, subject to the applicable Cisco plan. For quota-based incentive pay, Cisco typically pays as follows: * .75% of incentive target for each 1% of revenue attainment up to 50% of quota; * 1.5% of incentive target for each 1% of attainment between 50% and 75%; * 1% of incentive target for each 1% of attainment between 75% and 100%; and * Once performance exceeds 100% attainment, incentive rates are at or above 1% for each 1% of attainment with no cap on incentive compensation. For non-quota-based sales performance elements such as strategic sales objectives, Cisco may pay 0% up to 125% of target. Cisco sales plans do not have a minimum threshold of performance for sales incentive compensation to be paid. The applicable full salary ranges for this position, by specific state, are listed below: New York City Metro Area: $199,700.00 - $292,800.00 Non-Metro New York state & Washington state: $174,500.00 - $260,500.00 * For quota-based sales roles on Cisco's sales plan, the ranges provided in this posting include base pay and sales target incentive compensation combined. Employees in Illinois, whether exempt or non-exempt, will participate in a unique time off program to meet local requirements.
    $199.7k-292.8k yearly 29d ago
  • R&D Scientist/Technologist

    Nellson Nutraceutical 4.3company rating

    Principal research scientist job in Ontario, CA

    Join NELLSON and Become Part of a Winning Team of Professionals! We currently have an immediate opportunity for R&D Scientist to join the BAR DIVISION at our ONTARIO, CALIFORNIA location. Provide effective and functional technical support within the current R&D organization leadership. Responsible for the development of nutritional bar products for both new and existing Nellson customers. Provide data based technical leadership for innovation and product development from ideation to commercialization, utilizing standard best practices and procedures with hands on scale up and commercialization support. Collaborate with cross-functional disciplines to accomplish project goals. ESSENTIAL JOB DUTIES AND RESPONSIBILITIES: Support and lead the development of commercially successful and innovative new products for the bar business. Develop an effective relationship and work closely with the QA, Sales, Operations, and Nellson customers. Gain full command of internal formulation system for food product development and commercialization. Support and lead ideation and development of innovative products and platforms via formulation and/or process driven technologies using customer/marketing insights and existing/new technologies. Maintain awareness of market trends and comparative products. Ability to clearly present and articulate product ideas and innovations to internal and external customers. Ability to identify and qualify new equipment and/or processes for new product commercialization (US only). Ability to run and monitor bench-top and manufacturing scale-up batches. Ability to conduct shelf-life testing protocols, including the preparation and/or review shelf-life testing protocols. Preparation and/or manufacture of shelf-life testing samples. Monitoring, evaluation, and summary of results for shelf-life test results. Support R&D team through the identification and sourcing of new, novel ingredients. Gain full command of process systems for effective and sustainable product commercialization and apply product development processes to ensure formulation robustness for commercialization. Support and lead product transfers from other processing locations for maximizing schedule flexibility, efficiency, and lowest cost production. Capture and analyze key process data to determine and communicate key process variables and execute corrective action steps. (US only) Assist R&D project Sr Scientist in completing development and commercialization of new products. Develop a network of outside contacts such as customers, vendors, consultants, and educators. Performs Technical Reports writing as required. Performs other related duties as assign. PERSONAL ATTRIBUTES: Strong problem solving and critical thinking skills for trouble shooting and expanding current equipment capital for developing new product forms and formats. Knowledge and practical experience with shelf stable water activity-controlled food products and/or functional foods product development, processing equipment and techniques and regulatory requirements. Advance communication skills, both written and verbal (French and English for Canadian positions). Ability to speak effectively in front of groups of customers or employees. Demonstrate attention to detail. Must work will in group problem solving and exhibit sound judgement. Ability to prioritize and use time effectively while managing competing demands. Contribute to building a positive team spirit and display a high amount of professionalism. Responds promptly to customer needs. A firm foundation in food engineering and food science is required. Strong product formulation skills. Firm understanding of ingredient functionality and nutrition. High level of professionalism and diplomacy. Experience conducting plant trials/ process validation testing. Demonstrates self-management by consistently at work and on-time, takes responsibility for own actions, takes initiative, generates suggestions for improving work, meets productivity standards, and monitors own work to ensure quality. QUALIFICATIONS AND EXPERIENCE: Requires a minimum of 3 years of experience in the food industry. Requires a four-year college or university degree or its equivalent in Food Engineering Sciences, Food Science, or other relevant science degree. Knowledge and Experience with Design of Experiment (DOE) techniques. At Nellson, we invest in highly talented individuals and provide them with opportunities to continuously learn and grow to realize their full potential. Our state-of-the-art facilities, warehouses, and corporate offices offer a knowledgeable and professional environment to employees. By joining our performance-oriented team, you will be able to put your expertise to use and positively impact many groups across our production process. Nellson offers competitive pay, career growth opportunities, and an outstanding benefits program that features: * Medical, Dental & Vision Coverage * Generous Paid Time Off * 401(k) with Company Match * Flexible schedules * Professional Development & Tuition Reimbursement * And Many More Employee-Friendly Programs! Nellson is proud to be an Equal Opportunity Employer. All applicants receive consideration without regard to race, color, religion, gender, national origin, age, disability, veteran status or any other status protected by law. You may visit our website at ****************** to view current job openings.
    $83k-118k yearly est. Auto-Apply 5d ago
  • Senior Scientist - JJMT Electrophysiology

    6010-Biosense Webster Legal Entity

    Principal research scientist job in Irvine, CA

    At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at ******************* Job Function: Medical Affairs Group Job Sub Function: Medical Affairs Job Category: Scientific/Technology All Job Posting Locations: Irvine, California, United States of America Job Description: Our J&J MedTech Electrophysiology Medical Affairs team is currently recruiting for a Senior Scientist. This position is located in Irvine, California. Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow and profoundly impact health for humanity. Learn more at *******************/. Fueled by innovation at the intersection of biology and technology, we're developing the next generation of smarter, less invasive, more personalized treatments. Are you passionate about improving and expanding the possibilities of Cardiovascular? Ready to join a team that's reimagining how we heal? Our Cardiovascular team develops leading solutions for heart recovery, electrophysiology, and stroke. You will join a proud heritage of continually elevating standards of care for stroke, heart failure and atrial fibrillation (AFib) patients. Your unique talents will help patients on their journey to wellness. Learn more at *******************/medtech Job Responsibilities: This Medical Affairs Senior Scientist will be responsible for supporting one or several product development projects within the JJMT EP's product portfolio while fostering strong, productive relationships with colleagues across the organization. Under general direction and in accordance with all applicable federal, state and local laws/regulations and Corporate Johnson & Johnson, procedures and guidelines, this position is: Responsible for executing the clinical strategy to support product characterization and design features Will develop and execute product and/or procedural protocols for evidence generation Collaborate with evidence generation colleagues for evidence generation for new and existing products in order to support regulatory approval/clearance Provide scientific and test method expertise during study design development Provide pre-clinical insight to the development teams for the risk assessment Qualifications: Education BS with at least 6 years, MS with at least 4 years, PhD with at least 2 years of relevant experience in Engineering, Life Sciences, Physical Sciences, Nursing, or Biological Science is required. Experience An understanding of cardiac anatomy and medical devices are required. A minimum of 3 years working on pre-clinical models is required, with chronic models is preferred. Advanced technical writing skills is required with an emphasis on organizing data and presenting findings, with a demonstrated success in medical data generation, interpretation, and publications are highly preferred A proven working knowledge of catheter laboratory equipment and operating room procedures Experience in working with a global cross-functional teams is required. Must be able to work in a high stress environment with minimal supervision. Proven project management skills, with a demonstrable track record of success managing multiple projects Must be able to collaborate well with multiple partners and work effectively in a matrix environment Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via *******************/contact-us/careers . Internal employees contact AskGS to be directed to your accommodation resource. Required Skills: Preferred Skills: Analytical Reasoning, Clinical Research and Regulations, Clinical Trials Operations, Coaching, Collaborating, Communication, Critical Thinking, Data Analysis, Data Savvy, Digital Culture, Digital Literacy, Healthcare Trends, Medical Affairs, Medical Communications, Medical Compliance, Product Development Lifecycle, Report Writing, Stakeholder Engagement, Technologically Savvy The anticipated base pay range for this position is : $109,000.00 - $174,800.00 Additional Description for Pay Transparency: Subject to the terms of their respective plans, employees are eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)). Subject to the terms of their respective policies and date of hire, employees are eligible for the following time off benefits: Vacation -120 hours per calendar year Sick time - 40 hours per calendar year Holiday pay, including Floating Holidays -13 days per calendar year Work, Personal and Family Time - up to 40 hours per calendar year Parental Leave - 480 hours within one year of the birth/adoption/foster care of a child Bereavement Leave - 240 hours for an immediate family member: 40 hours for an extended family member per calendar year Caregiver Leave - 80 hours in a 52-week rolling period10 days Volunteer Leave - 32 hours per calendar year Military Spouse Time-Off - 80 hours per calendar year For additional general information on Company benefits, please go to: - *********************************************
    $109k-174.8k yearly Auto-Apply 4d ago
  • Senior Scientist - JJMT Electrophysiology

    8427-Janssen Cilag Manufacturing Legal Entity

    Principal research scientist job in Irvine, CA

    At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at ******************* Job Function: Medical Affairs Group Job Sub Function: Medical Affairs Job Category: Scientific/Technology All Job Posting Locations: Irvine, California, United States of America Job Description: Our J&J MedTech Electrophysiology Medical Affairs team is currently recruiting for a Senior Scientist. This position is located in Irvine, California. Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow and profoundly impact health for humanity. Learn more at *******************/. Fueled by innovation at the intersection of biology and technology, we're developing the next generation of smarter, less invasive, more personalized treatments. Are you passionate about improving and expanding the possibilities of Cardiovascular? Ready to join a team that's reimagining how we heal? Our Cardiovascular team develops leading solutions for heart recovery, electrophysiology, and stroke. You will join a proud heritage of continually elevating standards of care for stroke, heart failure and atrial fibrillation (AFib) patients. Your unique talents will help patients on their journey to wellness. Learn more at *******************/medtech Job Responsibilities: This Medical Affairs Senior Scientist will be responsible for supporting one or several product development projects within the JJMT EP's product portfolio while fostering strong, productive relationships with colleagues across the organization. Under general direction and in accordance with all applicable federal, state and local laws/regulations and Corporate Johnson & Johnson, procedures and guidelines, this position is: Responsible for executing the clinical strategy to support product characterization and design features Will develop and execute product and/or procedural protocols for evidence generation Collaborate with evidence generation colleagues for evidence generation for new and existing products in order to support regulatory approval/clearance Provide scientific and test method expertise during study design development Provide pre-clinical insight to the development teams for the risk assessment Qualifications: Education BS with at least 6 years, MS with at least 4 years, PhD with at least 2 years of relevant experience in Engineering, Life Sciences, Physical Sciences, Nursing, or Biological Science is required. Experience An understanding of cardiac anatomy and medical devices are required. A minimum of 3 years working on pre-clinical models is required, with chronic models is preferred. Advanced technical writing skills is required with an emphasis on organizing data and presenting findings, with a demonstrated success in medical data generation, interpretation, and publications are highly preferred A proven working knowledge of catheter laboratory equipment and operating room procedures Experience in working with a global cross-functional teams is required. Must be able to work in a high stress environment with minimal supervision. Proven project management skills, with a demonstrable track record of success managing multiple projects Must be able to collaborate well with multiple partners and work effectively in a matrix environment Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via *******************/contact-us/careers . Internal employees contact AskGS to be directed to your accommodation resource. Required Skills: Preferred Skills: Analytical Reasoning, Clinical Research and Regulations, Clinical Trials Operations, Coaching, Collaborating, Communication, Critical Thinking, Data Analysis, Data Savvy, Digital Culture, Digital Literacy, Healthcare Trends, Medical Affairs, Medical Communications, Medical Compliance, Product Development Lifecycle, Report Writing, Stakeholder Engagement, Technologically Savvy The anticipated base pay range for this position is : $109,000.00 - $174,800.00 Additional Description for Pay Transparency: Subject to the terms of their respective plans, employees are eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)). Subject to the terms of their respective policies and date of hire, employees are eligible for the following time off benefits: Vacation -120 hours per calendar year Sick time - 40 hours per calendar year Holiday pay, including Floating Holidays -13 days per calendar year Work, Personal and Family Time - up to 40 hours per calendar year Parental Leave - 480 hours within one year of the birth/adoption/foster care of a child Bereavement Leave - 240 hours for an immediate family member: 40 hours for an extended family member per calendar year Caregiver Leave - 80 hours in a 52-week rolling period10 days Volunteer Leave - 32 hours per calendar year Military Spouse Time-Off - 80 hours per calendar year For additional general information on Company benefits, please go to: - *********************************************
    $109k-174.8k yearly Auto-Apply 6d ago
  • SCIENTIST III / SENIOR

    LGM Pharma, LLC

    Principal research scientist job in Irvine, CA

    Job Description We are in need of a R&D Scientist III/Senior to join the R&D Team located in Irvine, Ca. PRIMARY DUTIES AND RESPONSIBILITIES: Perform analytical tests (wet chemistry, assay, impurity/degradant, dissolution and residual solvents in raw materials and finished products according to USP or in-house methods. Analyze organic and inorganic compounds to determine chemical and physical properties. Develop stability-indicating test methods for finished products. Design method validation protocols and write reports, perform method validation or verification for API and drug products. Conduct research and troubleshoot for instruments, methods, and tests with supervision. Coordinate with Quality Control department to smoothly transfer the method to QC chemists. Responsible for calculations and recording results of all tests in lab books and laboratory reports with good documentation practice for cGMP compliance. Perform peer review on lab notebooks, logbooks, and lab records. Train new chemists. Other related duties assigned by lab Director. REQUIRED SKILLS, ABILITIES, AND QUALIFICATIONS: Bachelor's degree (BS) or higher in Chemistry or equivalent combination of education and experience 5 + years of related experience and/or training in a Pharmaceutical company on small molecules with good documentation practice/cGMP. Developed and validated analytical methods using HPLC, or GC, for assay, impurity, residual solvents, and dissolution. Hands on experience using Empower software. Experience in supporting CMC documents for ANDA filing is preferred. Work well in a team environment with good communication skillset in both verbal and written English language for clear and accurate documentation of results and communication for project update. Mastery in calculations with good lab records for lab notebooks, logbooks, and laboratory reports according to good documentation practice for cGMP compliance. Ability to understand cGMP principles and FDA regulations for drug product development. Lead and train junior Scientist taking initiative in prioritization and implementation of work. Ability to interpret scientific and regulatory articles and documents, such as method development publications, FDA regulations, USP monographs and general chapter tests, safety rules, and procedures. Experienced in applying mathematical operations for determination of test reliability and validity, analysis of variance or RSD, correlation coefficient with linear regression, as well as difference (f1) and similarity factor (f2). Ability to define problems, collect data, establish facts, and draw valid conclusions. Ability to accurately interpret and implement variety of technical instructions and procedures. Experience with FDA audit for cGMP compliance is desirable. Experience on wet chemistry and HPLC/GC Proficiency with MS Office programs (Word, Excel, Power point). Ability to foster good teamwork and leadership skills. At LGM Pharma, we always take pride in putting our people first. We are an equal opportunity employer. We offer medical, dental, vision and company matching 401K. All suitably qualified candidates will receive consideration for employment based on objective work-related criteria and without regard for the following: age, disability, ethnic origin, gender, marital status, race, religion, responsibility of dependents, sexual orientation, or gender identity or other characteristics in accordance with the applicable governing laws.
    $108k-174k yearly est. 21d ago
  • SCIENTIST III / SENIOR

    LGM Pharma Solutions LLC

    Principal research scientist job in Irvine, CA

    We are in need of a R&D Scientist III/Senior to join the R&D Team located in Irvine, Ca. PRIMARY DUTIES AND RESPONSIBILITIES: * Perform analytical tests (wet chemistry, assay, impurity/degradant, dissolution and residual solvents in raw materials and finished products according to USP or in-house methods. * Analyze organic and inorganic compounds to determine chemical and physical properties. * Develop stability-indicating test methods for finished products. * Design method validation protocols and write reports, perform method validation or verification for API and drug products. * Conduct research and troubleshoot for instruments, methods, and tests with supervision. * Coordinate with Quality Control department to smoothly transfer the method to QC chemists. * Responsible for calculations and recording results of all tests in lab books and laboratory reports with good documentation practice for cGMP compliance. * Perform peer review on lab notebooks, logbooks, and lab records. * Train new chemists. * Other related duties assigned by lab Director. REQUIRED SKILLS, ABILITIES, AND QUALIFICATIONS: * Bachelor's degree (BS) or higher in Chemistry or equivalent combination of education and experience * 5 + years of related experience and/or training in a Pharmaceutical company on small molecules with good documentation practice/cGMP. * Developed and validated analytical methods using HPLC, or GC, for assay, impurity, residual solvents, and dissolution. Hands on experience using Empower software. * Experience in supporting CMC documents for ANDA filing is preferred. * Work well in a team environment with good communication skillset in both verbal and written English language for clear and accurate documentation of results and communication for project update. * Mastery in calculations with good lab records for lab notebooks, logbooks, and laboratory reports according to good documentation practice for cGMP compliance. * Ability to understand cGMP principles and FDA regulations for drug product development. * Lead and train junior Scientist taking initiative in prioritization and implementation of work. * Ability to interpret scientific and regulatory articles and documents, such as method development publications, FDA regulations, USP monographs and general chapter tests, safety rules, and procedures. * Experienced in applying mathematical operations for determination of test reliability and validity, analysis of variance or RSD, correlation coefficient with linear regression, as well as difference (f1) and similarity factor (f2). * Ability to define problems, collect data, establish facts, and draw valid conclusions. * Ability to accurately interpret and implement variety of technical instructions and procedures. * Experience with FDA audit for cGMP compliance is desirable. * Experience on wet chemistry and HPLC/GC * Proficiency with MS Office programs (Word, Excel, Power point). * Ability to foster good teamwork and leadership skills. At LGM Pharma, we always take pride in putting our people first. We are an equal opportunity employer. We offer medical, dental, vision and company matching 401K. All suitably qualified candidates will receive consideration for employment based on objective work-related criteria and without regard for the following: age, disability, ethnic origin, gender, marital status, race, religion, responsibility of dependents, sexual orientation, or gender identity or other characteristics in accordance with the applicable governing laws.
    $108k-174k yearly est. 51d ago
  • Postdoc/Research Scientist - Next Generation Sequencing (NGS)

    Zymo Research Corporation

    Principal research scientist job in Irvine, CA

    Zymo Research is looking for a dynamic individual to join our Research and Development, NGS Team! As a Scientist in the NGS group at Zymo Research, you will play a key role in driving innovation across next-generation sequencing (NGS) technologies, from RNA-Seq and epigenetics to metagenomics and microbiome analysis. You will design and execute high-impact research that shapes Zymo's next wave of products and scientific discoveries. This role is ideal for an ambitious and creative scientist who can integrate molecular biology, sequencing technology, and bioinformatics to develop groundbreaking solutions. The successful candidate will collaborate extensively with the Bioinformatics, Automation, and Commercial/Marketing teams, translating scientific advances into robust, user-friendly tools and assays. You will also have the opportunity to grow into a leadership role overseeing the broader NGS department, encompassing epigenomics, genomics, microbiomics, and transcriptomics initiatives. Your work will directly contribute to Zymo's mission of “making science simple”, delivering world-class NGS solutions that accelerate discovery and clinical translation. Join us in making a meaningful impact! Essential Duties and Responsibilities Innovation and Research Leadership Conceive, design, and execute innovative NGS-based methods and workflows for applications in RNA sequencing, epigenetics, metagenomics, and clinical diagnostics. Drive R&D projects from concept through validation and commercialization, ensuring scientific rigor, efficiency, and alignment with company goals. Evaluate and integrate emerging sequencing platforms and technologies (e.g., Illumina, Oxford Nanopore, PacBio, Element Biosciences) to maintain Zymo's technological leadership. Identify opportunities to expand Zymo's NGS portfolio into novel biological domains and multi-omics integration. Cross-Functional Collaboration Work closely with Bioinformatics to design, validate, and interpret complex sequencing datasets and analysis pipelines. Partner with Automation Engineers to streamline NGS workflows for scalability and reproducibility. Collaborate with Product Development and Marketing teams to define technical specifications, generate application data, and support product launch activities. Contribute to customer engagement efforts through beta testing, data-driven presentations, and scientific discussions. Scientific Excellence and Mentorship Supervise and mentor Research Associates, Technicians, and Interns, fostering a culture of scientific curiosity and excellence. Lead internal technical workshops and training sessions to disseminate best practices and promote innovation. Author technical reports, white papers, scientific publications, and conference presentations to communicate findings internally and externally. Project Management and Compliance Manage project timelines, budgets, and resource allocation to deliver milestones efficiently. Maintain thorough documentation in compliance with Zymo's policies, quality systems, and regulatory standards (e.g., ISO, CLIA). Ensure data integrity, reproducibility, and adherence to biosafety standards in all research activities. Professional Development and Scientific Engagement Stay current on advances in sequencing, automation, and data analytics through literature, conferences, and collaborations. Represent Zymo Research at scientific meetings, symposia, and academic partnerships. Help shape the strategic direction of the NGS group as it evolves into a multidisciplinary innovation hub. Qualifications: Education and Experience Ph.D. in Molecular Biology, Genetics, Genomics, Bioengineering, or a related discipline. Proven expertise in RNA biology, epigenetics, microbiomics, or other NGS-related areas. Hands-on experience in library preparation, sequencing platform operation, and data analysis. Strong publication record (minimum of two first-author peer-reviewed papers). Experience mentoring junior scientists or managing laboratory projects. Preferred Experience Development of bioinformatics pipelines and integration of wet-lab and dry-lab workflows. Proven record in translating research into commercial NGS products or services. Familiarity with automation systems and high-throughput sequencing platforms such as Illumina, Oxford Nanopore, or PacBio. Knowledge of regulatory or quality standards such as ISO 13485, CLIA, or GLP. Core Competencies Scientific Innovation: Visionary mindset with the ability to transform novel ideas into impactful solutions. Technical Mastery: Deep understanding of molecular biology, sequencing technologies, and data interpretation. Leadership and Mentorship: Capable of growing into a leadership role guiding a multidisciplinary NGS department. Collaboration: Strong interpersonal communication skills to thrive in cross-functional teams. Project Management: Skilled at planning, prioritizing, and executing multiple projects simultaneously. Communication: Clear, engaging communicator across technical and non-technical audiences. About Us: Since its inception in 1994, Zymo Research has been proudly serving the scientific community by providing innovative, reliable, and high-quality research tools and products. Whether it's DNA, RNA, epigenetics, microbiomics, protein, or yeast-based research, our philosophy remains the same: To provide the highest quality products in the industry while ensuring they are both simple to use and reliable in their performance. Recognized as a Top Workplace by the Orange County Register in 2021, 2022, and named a Top Workplace USA in 2023, Zymo Research continues to be a vibrant community where employees thrive, feel connected, and are inspired by their work. If you are passionate about contributing to scientific advancement and want to be part of an exceptional team in a dynamic, growing company, we'd love to hear from you! Compensation, Benefits, and Perks: The estimated base compensation range for this position is $70,000 - $110,00 a year at the time of posting. Actual compensation details will be provided in writing at the time of offer, if applicable, and is based on several factors we believe fairly and accurately impact compensation, including geographic location, experience, knowledge, skills, abilities, and other job permitted factors. Zymo Research also offers competitive benefits and perks including: Medical, Dental, Vision, and Life Insurance Coverages EAP Sessions Vacation Time plus Company Holidays Paid Sick Leave Generous 401(K) with matching Employee Referral Bonus Complimentary fruit, snacks, and beverages Complimentary catered lunches on Thursdays Complimentary EV Charging Equal Employment Opportunity Employer: Zymo Research welcomes candidates of all backgrounds. These include sex, age, color, race, religion, marital status, national origin, ancestry, sexual orientation, gender, gender identity, gender expression, physical & mental disability, medical condition, genetic information, military and veteran status, or any other protected status as defined by federal, state, or local law. Location: Onsite - Zymo Research Operations/HQ - 17062 Murphy Ave., Irvine, CA 92614 Disclaimer: At Zymo, we take the integrity of our hiring process seriously. Please be aware of fraudulent recruitment activities that may use our name to deceive job seekers. We will never ask for payment, sensitive personal information, or financial details during the recruitment process. All legitimate communications will come from an official Zymo or TriNet Hiring email address. If you are contacted by anyone claiming to represent us using a free email service (e.g., Gmail, Yahoo, Hotmail) or asking for payment, please treat this as fraudulent and report it immediately to *******************
    $70k-110k yearly 56d ago
  • Sr. Scientist II -Toxicology

    Global 4.1company rating

    Principal research scientist job in Aliso Viejo, CA

    Sr. Scientist II - Toxicology The Sr. Scientist II, Toxicologist reporting to the Sr. Director of Toxicology and Biocompatibility is responsible for providing subject matter expertise and leadership in toxicology and nonclinical development at the team and development project level. What You'll Do: The design, execution (including monitoring) and reporting on in vivo toxicology studies supporting the nonclinical development of new ophthalmic therapeutics and drug delivery devices and contributing to the regulatory submissions enabling their testing in clinical studies. These studies include safety/tolerability testing of novel formulation in nonclinical models. Contribute to the nonclinical development plan needed to satisfy clinical internal and regulatory requirements on a project basis. Participate in Project Team Meetings, and interfacing with internal/external scientists from other disciplines. Authors nonclinical study protocols and reports to support IND/IMPD/NDA/IMPD/PLA submission toxicology studies. Evaluating published/unpublished data and providing risk evaluation on new ingredients for regulatory submissions and clinical trials. Serving as a Study Monitor to ensure optimal testing requirements are implemented for each study. Providing interpretation and authoring research reports in compliance with GLP regulations to support the safety of new pharmaceutical, device, and combination products. Possessing a comprehensive understanding and hands-on experience in conducting different study types in diverse pre-clinical settings. Design and execute nonclinical toxicity study plans 40% Establishes the development plan for nonclinical toxicity studies needed to satisfy clinical, internal and regulatory requirements. As Study Monitor, designs studies to maximize the quantity and quality of data and ensure adequate safety information is obtained from the study. Schedules and executes toxicology studies based on project priorities to ensure orderly and timely progression within set target dates. When acting as Study Monitor, assumes oversight for the technical conduct of studies and collaborates with the Study Director to assure that all aspects of studies are performed in accordance with Good Laboratory Practices (GLP) regulations, when specified, as mandated by the FDA. Serves as key contact for outsourced studies and assures that studies are executed according to protocol, SOP and contract. Evaluates CROs and obtains study bids/quotes, develops study protocols. Data review and reporting 40% Reviews and summarizes study data to provide interpretation, conclusions, and recommendations. Reviews and approves the interpretation, analysis, documentation and reporting of results of nonclinical studies by CROs to assure accurate safety assessments of drugs and devices. Reviews and approves summaries of safety evaluations prepared for internal research release documents, regulatory agencies (IND summaries) and clinical investigator brochures. Authors relevant sections of regulatory documents (i.e. IND, NDA) Interdepartmental and project team participation 15% Provides subject matter expertise and leadership in toxicology and nonclinical development at the team and development project level. Participates in project team meetings. Provides scheduling and technical input and plays an integral role in the project functional development plans. Proactively communicates with the team leaders and members on a regular basis and promptly notifies functional head and team leaders of issues. Scouting, new opportunity evaluation 5% Evaluates available information/literature and provides technical expertise to assess and advise on the safety of new ingredients, compounds, acquisitions and competitor products. Prepares risk assessments and summaries for support of various research, clinical and regulatory activities. Exercises good judgement in recommending issues related to safety. How You'll Get There: 8 years min. medical device or pharmaceuticals M.S. degree in Biological Sciences and/or toxicology with +10 years of experience. A PhD Biological Sciences and/or toxicology +8 years of experience. At least 4 years of understanding and working with GLP and working in a pre-clinical setting. Broad understanding Good Laboratory Practices, care policies and FDA regulations, is desired. Skilled use of ocular anatomy, physiology and toxicology principles, theories and concepts. Excellent analytical and communication skills, both verbal and written, Excellent interpersonal skills, emotional intelligence and ability to negotiate. Some travel required #GKOSUS
    $110k-171k yearly est. Auto-Apply 60d+ ago
  • Staff Research Scientist - Packaging Innovation

    Niagara Water 4.5company rating

    Principal research scientist job in Diamond Bar, CA

    At Niagara, we're looking for Team Members who want to be part of achieving our mission to provide our customers the highest quality most affordable bottled water. Consider applying here, if you want to: Work in an entrepreneurial and dynamic environment with a chance to make an impact. Develop lasting relationships with great people. Have the opportunity to build a satisfying career. We offer competitive compensation and benefits packages for our Team Members. Staff Research Scientist - Packaging InnovationThe Staff Scientist of Innovation will lead cross-disciplinary Innovation initiatives that advance Niagara's products and packaging systems through design science, digital simulation, and consumer-centered innovation. This role will focus on understanding and optimizing product-process-performance relationships at the system level - across bottles, closures, packaging configurations, and manufacturing conditions - to drive sustainability, performance, and user experience improvements. The Staff Scientist will advance product portfolio by translating scientific insights into holistic product solutions that can be scaled through Niagara's global manufacturing network. Essential Functions Formulates strategy for Innovation growth. Drive system-level optimization that balance performance, sustainability, and manufacturability. Apply inventive principles, TRIZ theory or Innovation by association approach to brainstorm ideas, solve problems with out of the box thinking. Explore and develop emerging technologies and trends to integrate with Innovation initiatives. Lead R&D projects focused on the interaction of design, structure, and performance across packaging systems. Advance the use of AI, machine learning, or DOE-based analytics in R&D decision-making. Conduct human factors research to quantify usability, ergonomics, and consumer interaction with packaging systems. Partner with design, insights, and marketing teams to translate consumer needs into products, engineering and performance requirements. Quantify environmental trade-offs and support company-wide carbon reduction initiatives through design improvements Ensures project documentation and communication between all stakeholders. Initiates, develops, and maintains relationships with suppliers and other external collaborators. Present and communicate research results internally and externally and help develop intellectual property. Please note this job description is not designed to contain a comprehensive list of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities and activities may change at any time with or without prior notice. Qualifications Minimum Qualifications: 6 Years - Experience in Engineering, R&D, mechanical or industrial design, instrumentation etc. 6 Years - Experience in Position, Research laboratory assistant, post -doctoral scholar 4 Years - Experience working with graduate researchers, interns or lab assistants *experience may include a combination of work experience and education Preferred Qualifications: 10+ Years- Experience in Engineering, R&D, mechanical or industrial design, instrumentation etc. 10+ Years - Experience in Position, Research laboratory assistant, post -doctoral scholar 6 Years - Experience working with graduate researchers, interns or lab assistants *experience may include a combination of work experience and education Competencies Proficiency in, but not limited to: Advanced data analysis and simulation capabilities Publication quality communication skills (documents and presentations) Proven experience with analytical laboratory equipment Skills with lab data management or automation software such as LabVIEW, Matlab, Python. Microsoft Office Products. Problem Solving - identifies and resolves problems in a timely manner; gathers and analyzes information skillfully. Detail oriented and accurate - minimizes mistakes, follows every step in a process and follows through with all tasks Oral Communication - speaks clearly and persuasively in positive or negative situations; demonstrates presentation skills. Written Communication - writes clearly and informatively; presents numerical data effectively; able to read and interpret written information. Beneficial, but not required: Injection molding or blow molding experience. Lifting Requirements: 40 lbs. For example, must be physically capable to change injection molds and resin in lab or production equipment. Physical Demands: Travel up to 15%. Some work in hot, cold, or confined production environments. Must be able to operate tools used when changing molds and operating R&D equipment. This position embodies the values of Niagara's LIFE competency model, focusing on the following key drivers of success: Lead Like an Owner Makes safety the number one priority Keeps alert for safety issues and escalates immediately Effectively prioritizes tasks based on department goals Shows respect to others and confronts interpersonal issues directly Prioritizes resolution of customer issues effectively Responds promptly and honors commitments to internal and external customers InnovACT Makes recommendations to continuously improve policies, methods, procedures, and/or products Demonstrates adaptability by reacting appropriately to unexpected changes in situations or circumstances Increases performance through greater efficiency Find a Way Seeks to develop technical knowledge through learning from other experts Understands interdepartmental impact of individual decisions and actions Seeks solutions rather than placing blame Empowered to be Great Consistently looks for ways to improve one's self through growth and development opportunities Communicates clearly and promptly up, down, and across Communicates effectively to manage expectations Education Minimum Required: Ph.D in Chemical/ Materials/ Mechanical engineering and other related fields or equivalent experience. Preferred: Ph.D in Mechanical Engineering or equivalent experience. Materials Science and Engineering exposure. Polymer processing or science and Packaging training. Foreign Language Required: None Required Preferred: Minimum Professional Proficiency, Spanish Typical Compensation Range Pay Rate Type: Salary$123,641.54 - $176,189.21 / YearlyBonus Target: 10% Annual Benefits *********************************************** * *Los Angeles County applicants only** Qualified applicants with arrest or conviction records will be considered for employment in accordance with the Los Angeles County Fair Chance Ordinance for Employers, the California Fair Chance Act, and any other applicable local and state laws. Any employment agency, person or entity that submits a résumé into this career site or to a hiring manager does so with the understanding that the applicant's résumé will become the property of Niagara Bottling, LLC. Niagara Bottling, LLC will have the right to hire that applicant at its discretion without any fee owed to the submitting employment agency, person or entity. Employment agencies that have fee agreements with Niagara Bottling, LLC and have been engaged on a search shall submit résumé to the designated Niagara Bottling, LLC recruiter or, upon authorization, submit résumé into this career site to be eligible for placement fees.
    $123.6k-176.2k yearly Auto-Apply 60d+ ago
  • Sr. Scientist II -Toxicology

    Glaukos Corporation 4.9company rating

    Principal research scientist job in Aliso Viejo, CA

    Sr. Scientist II - Toxicology The Sr. Scientist II, Toxicologist reporting to the Sr. Director of Toxicology and Biocompatibility is responsible for providing subject matter expertise and leadership in toxicology and nonclinical development at the team and development project level. What You'll Do: The design, execution (including monitoring) and reporting on in vivo toxicology studies supporting the nonclinical development of new ophthalmic therapeutics and drug delivery devices and contributing to the regulatory submissions enabling their testing in clinical studies. These studies include safety/tolerability testing of novel formulation in nonclinical models. Contribute to the nonclinical development plan needed to satisfy clinical internal and regulatory requirements on a project basis. Participate in Project Team Meetings, and interfacing with internal/external scientists from other disciplines. Authors nonclinical study protocols and reports to support IND/IMPD/NDA/IMPD/PLA submission toxicology studies. Evaluating published/unpublished data and providing risk evaluation on new ingredients for regulatory submissions and clinical trials. Serving as a Study Monitor to ensure optimal testing requirements are implemented for each study. Providing interpretation and authoring research reports in compliance with GLP regulations to support the safety of new pharmaceutical, device, and combination products. Possessing a comprehensive understanding and hands-on experience in conducting different study types in diverse pre-clinical settings. Design and execute nonclinical toxicity study plans 40% Establishes the development plan for nonclinical toxicity studies needed to satisfy clinical, internal and regulatory requirements. As Study Monitor, designs studies to maximize the quantity and quality of data and ensure adequate safety information is obtained from the study. Schedules and executes toxicology studies based on project priorities to ensure orderly and timely progression within set target dates. When acting as Study Monitor, assumes oversight for the technical conduct of studies and collaborates with the Study Director to assure that all aspects of studies are performed in accordance with Good Laboratory Practices (GLP) regulations, when specified, as mandated by the FDA. Serves as key contact for outsourced studies and assures that studies are executed according to protocol, SOP and contract. Evaluates CROs and obtains study bids/quotes, develops study protocols. Data review and reporting 40% Reviews and summarizes study data to provide interpretation, conclusions, and recommendations. Reviews and approves the interpretation, analysis, documentation and reporting of results of nonclinical studies by CROs to assure accurate safety assessments of drugs and devices. Reviews and approves summaries of safety evaluations prepared for internal research release documents, regulatory agencies (IND summaries) and clinical investigator brochures. Authors relevant sections of regulatory documents (i.e. IND, NDA) Interdepartmental and project team participation 15% Provides subject matter expertise and leadership in toxicology and nonclinical development at the team and development project level. Participates in project team meetings. Provides scheduling and technical input and plays an integral role in the project functional development plans. Proactively communicates with the team leaders and members on a regular basis and promptly notifies functional head and team leaders of issues. Scouting, new opportunity evaluation 5% Evaluates available information/literature and provides technical expertise to assess and advise on the safety of new ingredients, compounds, acquisitions and competitor products. Prepares risk assessments and summaries for support of various research, clinical and regulatory activities. Exercises good judgement in recommending issues related to safety. How You'll Get There: 8 years min. medical device or pharmaceuticals M.S. degree in Biological Sciences and/or toxicology with +10 years of experience. A PhD Biological Sciences and/or toxicology +8 years of experience. At least 4 years of understanding and working with GLP and working in a pre-clinical setting. Broad understanding Good Laboratory Practices, care policies and FDA regulations, is desired. Skilled use of ocular anatomy, physiology and toxicology principles, theories and concepts. Excellent analytical and communication skills, both verbal and written, Excellent interpersonal skills, emotional intelligence and ability to negotiate. Some travel required #GKOSUS
    $106k-156k yearly est. Auto-Apply 60d+ ago
  • Associate Scientist, Conjugation Chemistry

    Allen Spolden

    Principal research scientist job in San Bernardino, CA

    We are looking for motivated synthetic chemist(s) to perform conjugation chemistry within our Discovery Chemistry group, to advance our cutting -edge RNA editing drug discovery programs. Responsibilities: Perform bioconjugation, purification, and characterization of novel conjugation and characterization methods involving oligonucleotides, and other novel molecules Identify critical issues/steps in a conjugation and solve the problems in a timely fashion Maintain a well -documented laboratory notebook Track progress against project timelines, generate regular status updates, and communicate progress and issues to management Adhere to safe laboratory practices Requirements / Qualifications: BS or MS Chemistry or Biochemistry degree with excellent understanding of organic and analytical chemistry with 4+ years experience Experience working in an organic synthesis laboratory or analytical laboratory Experience with a wide range of analytical techniques, especially HPLC and/or HPLC -MS Work authorization: United States (Required) Background Check Requirements Schedule: Monday to Friday Overtime Supplemental pay types: Bonus opportunities Education: Bachelor's (Preferred) Experience: Research & development: 1 year (Required) Conjugation: 1 year (Required) Purification: 1 year (Required) Chemistry: 1 year (Required) Work Location: In person Benefits Benefits: 401(k) 401(k) matching Dental insurance Employee assistance program Flexible spending account Health insurance Life insurance Paid time off Referral program Vision insurance
    $80k-130k yearly est. 60d+ ago
  • Staff Scientist - Analytical Pharmacology Core Facility

    Aa067

    Principal research scientist job in Duarte, CA

    Staff Scientist - Analytical Pharmacology Core Facility - (10033106) Description Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research. The Beckman Research Institute of City of Hope is looking for a talented Staff Scientist to perform several functions as a member of the Analytical Pharmacology Core Facility. Your primary role will include operation of the liquid chromatography tandem mass spectrometry (LC-MS/MS) instrumentation available in the core. These efforts will include not only operating the instrument but also assay development, sample preparation, calibration, data analysis, data management/backup and routine maintenance/trouble shooting. In addition, you will assist the director with the development and validation of new analytical methods for the quantitative analysis of large and small molecules in support of pharmacokinetic and biomarker investigations. As a successful candidate, you will:Develop and apply new and established LC-MS/MS and ICP-MS analytical methods. Perform data analysis, maintain records, report analytical results, prepare Standard Operating Procedures (SOPs) for sample preparation and analysis, and assist in manuscript preparation for publications. Perform preventative maintenance and troubleshooting of problems with laboratory equipment. Consult with core users regarding appropriateness of analytical methods and experimental design Coordinate sample collection and batch preparation together with other lab staff. Participate in and present findings at weekly lab meetings and provide cross-training to other lab members. Qualifications Your qualifications should include:Ph. D. , Pharm. D. or M. D/Ph. D. degree in Pharmacology, Analytical Chemistry, Life Sciences or related discipline with a background within preclinical and clinical pharmacokinetic studies. A Master's degree with a minimum of 3 years of experience in an analytical laboratory will also be considered. Previous experience using LC-MS/MS instrumentation for quantitative analysis of large and small molecules required. Experience with Waters and/or AB Sciex instruments is particularly desirable. Experience with ICP-MS analyses using an Agilent system is also desirable. Other important skills include knowledge of analytical chemistry and experience with instrument controller software programs, like MassLynx and Analyst . Knowledge of the principles of quantitative analysis and familiarity with the FDA's Biomedical Method Validation Guidance for Industry are also preferred. Strong interpersonal, documentation, and organizational skills, and a commitment to providing high-quality analytical chemistry services for users of the core facility are essential. City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location. City of Hope is an equal opportunity employer. To learn more about our Comprehensive Benefits, please CLICK HERE. Primary Location: United States-California-DuarteJob: ResearchWork Force Type: OnsiteShift: DaysJob Posting: Dec 17, 2025Minimum Hourly Rate ($): 38. 674337Maximum Hourly Rate ($): 127. 693000
    $84k-139k yearly est. Auto-Apply 16h ago
  • Archaeology Scientist II

    Firstcarbon Solutions 3.9company rating

    Principal research scientist job in Irvine, CA

    FirstCarbon Solutions (FCS) , an ADEC Innovation, is a full-service environmental consulting firm focused on improving the world we live in. It's our goal to improve the lives of all the people we work with, whether they are clients, partners, or colleagues. Come join our team of amazing professionals dedicated to making the world a better place! Position Summary FirstCarbon Solutions is seeking a mid-career to senior Archaeologist (CG06 - CG07) to join the team of Cultural Resources Specialists. The selected candidate will be responsible for soliciting, leading, and executing archaeological field projects, as well as providing training and development opportunities to junior staff. Experience with fieldwork such as surveys, monitoring, and excavation, along with research, technical report drafting, and review, is required. The position requires managing multiple projects, adhering to deadlines, and working collaboratively with clients, colleagues, and stakeholders. This role reports to either an FCS Senior Archaeologist or the FCS Director of Cultural Resources. Duties and Responsibilities Solicits and reviews Request for Proposals (RFP) from clients and lead agencies to determine project needs for cultural resources evaluations and prepares project-specific proposals for the appropriate cultural resources' compliance documents Conducts records searches in conjunction with the California Historical Resources Information System (CHRIS) Information Centers (IC) and reviews regional literature, historic maps, historic aerial photographs, and assessor parcel information. Performs field surveys, assembles, and manages larger survey teams, when necessary, collects and analyses data, and records resources in the appropriate Department of Parks and Recreation (DPR) forms. Carries out field work, consultation, and reporting requirements specifics for various lead agencies including, but not limited to: local city and county lead agencies under CEQA; state lead agencies such as California Department of Transportation (CalTrans); and federal lead agencies such as United States Army Corps of Engineers (USACE), Federal Aviation Administration (FAA), Federal Communications Commission (FCC), Bureau of Land Management (BLM), and Bureau of Reclamation Authors and reviews Phase I and Phase II Cultural Resources Assessments (CRA), cultural resources components of Initial Studies (IS) or Environmental Impact Reports (EIR), Historical Property Survey Reports (HPSR), and Archaeological Survey Reports (ASR) Prepares Data Recovery Programs (DRP) for projects requiring Phase II testing or Phase III excavation. Conducts Phase II and Phase III investigations to lead agency standards, which may include, but is not limited to: site delineation and GIS/GPS mapping, artifact plotting, drawing site sketch maps and taking field photos, surface collection, excavating Shovel Test Probes (STP), excavating Test Units (TU), recording depth and strata levels with off-set measurements, soil screening and sampling, artifact labeling and packaging, preparing artifact catalogs, artifact and assemblage analysis and interpretation, and artifact curation Authors and/or reviews Phase II testing and Phase III excavation reports, with all pertinent field data included and analyzed, to lead agency standards. Attends pre-construction meetings with contractor, client, lead agency and interested tribal parties in order to determine pre-established Mitigation Measures (MM) or Conditions of Approval (CoA) for grading or excavation projects requiring cultural resources monitoring. Prepares Mitigation Monitoring Plans (MMP), and Unanticipated Discovery Plans (UDP), as needed. Conducts and/or manages cultural resources monitoring and records resources in the appropriate Department of Parks and Recreation (DPR) forms, conducts additional Phase II testing or Phase III excavation if needed. Educates clients about compliance with cultural resource regulations, advises clients on options to minimize impacts on known cultural resources, and recommends courses of action based on regulatory compliance and professional interpretations. Authors and/or reviews Phase IV monitoring close out reports, with all pertinent field data included and analyzed, to lead agency standards. Assists in marketing FCS cultural resources services as well as participates in marketing and business development activities. Assist in monitoring staff's workload, schedules, project budgets, and participates in screening and interviewing prospective candidates for technical staff positions in the Cultural Resources Management Division Skills Has highly efficient and productive working habits and can handle multiple assignments simultaneously. Demonstrates excellent analytical and verbal communication skills. Have superior skills in preparing written documents. Effectively negotiates sufficient fees and determines contract terms. Prepares clear and appropriate scopes of work. Supervises establishment of subcontracts and ensures timely and successful subcontractor performance. Effectively supervises, trains, and enhances the capabilities of peers and subordinates. Demonstrates leadership skills by taking initiative, motivating, and helping others, sharing pertinent knowledge, emphasizing teamwork, and providing feedback. Proactively and creatively adapts to new work-related challenges. Maintains a highly professional image in all work-related activities. Registration with the Register of Professional Archaeologists (RPA) is a plus, as is involvement with professional organizations and institutions. Working familiarity with GIS/GPS programs such as Google Earth, ArcGIS, ArcMap, and use of .kml and .kmz files Expertise in MS Word, Excel, and Adobe Acrobat with familiarity in MS Access Reliable transportation to travel to project sites and meetings as needed. Familiarity with Deltek Vision is a plus. Education and Experience Bachelor of Science/Arts degree in Archaeology, or Architectural History. M.A. preferred. Minimum of 5 years' experience as a professional Archaeologist (SOI Qualified) Experience supervising laboratory and/or field crews is a plus Expertise in California Archaeology and general knowledge of the other Cultural Resources disciplines Familiarity with information resources in the scientific community, including other archaeologists, college and university programs, research centers and libraries, and data repositories. Expertise with sections relating to cultural resources in the California Environmental Quality Act (CEQA), the California Public Resources Code (PRC), the National Environmental Policy Act (NEPA), the Section 106 of the National Historic Preservation Act, the Archaeological Resources Protection Act (ARPA), and the Native American Graves Protection and Repatriation Act (NAGPRA), Understands field work, consultation, and reporting requirements specifics for various lead agencies including, but not limited to: local city and county lead agencies under CEQA; state lead agencies such as California Department of Transportation (Caltrans); and federal lead agencies such as United States Army Corps of Engineers (USACE), Federal Aviation Administration (FAA), Federal Communications Commission (FCC), Bureau of Land Management (BLM), and Bureau of Reclamation (USBR) Work Environment The position operates in a dynamic and highly collaborative working environment. FCS is dedicated to providing our staff the opportunity to elect remote, hybrid home/office as well as office location options. This role routinely uses standard office equipment and often requires field work in the form of records searches, pedestrian site surveys, archaeological testing, and data recovery. Physical Demands The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. While performing the duties of this job, the employee is regularly required to talk and hear; have hand/finger dexterity; and reach with hands and arms. The employee will spend extended periods of time in front of a computer/laptop. Specific vision abilities required by this job include close vision, distance vision, and ability to adjust focus. Compliance with all ADECi & FCS Travel and Workspace Policies that align with the CDC, local, state, and federal guidelines must be followed and upheld. Salary Range: $ $80,000 - 119,000 We offer competitive salaries based on experience and education. Our great comprehensive benefits also include personal and professional development opportunities. If you want to work in a collaborative, creative work environment where you can provide meaningful contributions while being challenged to grow on the job, then you are encouraged to apply! Competitive, progressive benefits, including Example: Full-time, regular employee Up to 100% employer paid premiums employee medical (with buy-up options) and up to 55% coverage for eligible dependent(s) Up to 80% employer-paid dental and vision covered premiums for employees. Eligible dependent coverage also available. Employer sponsored Group Life and AD&D insurance with discounted voluntary coverage also available Employer covered Short- & Long-Term Disability insurance Employee Assistance & Wellness Programs (EAP) 401(k) & Roth retirement savings accounts (see HR department for details on contributions and exclusions) Pet insurance discounts Volunteer programs, committees, and opportunities Mentorship program and Work/Life Balance initiatives *All benefits are subject to eligibility and may be changed at any time by the Company. Information Security Adhering to all policies, guidelines, and procedures pertaining to the protection of information of the organization, employees must maintain confidentiality of all sensitive information to which they are given access. They are also responsible for reporting actual or suspected events or incidents, including vulnerabilities or breaches, that may affect the confidentiality, integrity, and availability of information to members of the Management Team. Mutual Respect is fundamental. Fundamental to our teams. Fundamental to our clients. Fundamental to the communities we serve and live in. Fundamental to the landscapes we work within. We need you and your unique talents, history, and background to become the Company we aspire to be. We insist upon a culture of common respect, expect transparency, and celebrate the fundamental value and dignity of all individuals. Our mutual equality as humans is the path to diverse and innovative collaboration. We cultivate integrity, driving us to growth, and allowing us to achieve more together than we could ever hope to as individuals.
    $80k-119k yearly Auto-Apply 13d ago
  • Archaeology Scientist II

    Cameron Cole, LLC

    Principal research scientist job in Irvine, CA

    FirstCarbon Solutions (FCS) , an ADEC Innovation, is a full-service environmental consulting firm focused on improving the world we live in. It's our goal to improve the lives of all the people we work with, whether they are clients, partners, or colleagues. Come join our team of amazing professionals dedicated to making the world a better place! Position Summary FirstCarbon Solutions is seeking a mid-career to senior Archaeologist (CG06 - CG07) to join the team of Cultural Resources Specialists. The selected candidate will be responsible for soliciting, leading, and executing archaeological field projects, as well as providing training and development opportunities to junior staff. Experience with fieldwork such as surveys, monitoring, and excavation, along with research, technical report drafting, and review, is required. The position requires managing multiple projects, adhering to deadlines, and working collaboratively with clients, colleagues, and stakeholders. This role reports to either an FCS Senior Archaeologist or the FCS Director of Cultural Resources. Duties and Responsibilities Solicits and reviews Request for Proposals (RFP) from clients and lead agencies to determine project needs for cultural resources evaluations and prepares project-specific proposals for the appropriate cultural resources' compliance documents Conducts records searches in conjunction with the California Historical Resources Information System (CHRIS) Information Centers (IC) and reviews regional literature, historic maps, historic aerial photographs, and assessor parcel information. Performs field surveys, assembles, and manages larger survey teams, when necessary, collects and analyses data, and records resources in the appropriate Department of Parks and Recreation (DPR) forms. Carries out field work, consultation, and reporting requirements specifics for various lead agencies including, but not limited to: local city and county lead agencies under CEQA; state lead agencies such as California Department of Transportation (CalTrans); and federal lead agencies such as United States Army Corps of Engineers (USACE), Federal Aviation Administration (FAA), Federal Communications Commission (FCC), Bureau of Land Management (BLM), and Bureau of Reclamation Authors and reviews Phase I and Phase II Cultural Resources Assessments (CRA), cultural resources components of Initial Studies (IS) or Environmental Impact Reports (EIR), Historical Property Survey Reports (HPSR), and Archaeological Survey Reports (ASR) Prepares Data Recovery Programs (DRP) for projects requiring Phase II testing or Phase III excavation. Conducts Phase II and Phase III investigations to lead agency standards, which may include, but is not limited to: site delineation and GIS/GPS mapping, artifact plotting, drawing site sketch maps and taking field photos, surface collection, excavating Shovel Test Probes (STP), excavating Test Units (TU), recording depth and strata levels with off-set measurements, soil screening and sampling, artifact labeling and packaging, preparing artifact catalogs, artifact and assemblage analysis and interpretation, and artifact curation Authors and/or reviews Phase II testing and Phase III excavation reports, with all pertinent field data included and analyzed, to lead agency standards. Attends pre-construction meetings with contractor, client, lead agency and interested tribal parties in order to determine pre-established Mitigation Measures (MM) or Conditions of Approval (CoA) for grading or excavation projects requiring cultural resources monitoring. Prepares Mitigation Monitoring Plans (MMP), and Unanticipated Discovery Plans (UDP), as needed. Conducts and/or manages cultural resources monitoring and records resources in the appropriate Department of Parks and Recreation (DPR) forms, conducts additional Phase II testing or Phase III excavation if needed. Educates clients about compliance with cultural resource regulations, advises clients on options to minimize impacts on known cultural resources, and recommends courses of action based on regulatory compliance and professional interpretations. Authors and/or reviews Phase IV monitoring close out reports, with all pertinent field data included and analyzed, to lead agency standards. Assists in marketing FCS cultural resources services as well as participates in marketing and business development activities. Assist in monitoring staff's workload, schedules, project budgets, and participates in screening and interviewing prospective candidates for technical staff positions in the Cultural Resources Management Division Skills Has highly efficient and productive working habits and can handle multiple assignments simultaneously. Demonstrates excellent analytical and verbal communication skills. Have superior skills in preparing written documents. Effectively negotiates sufficient fees and determines contract terms. Prepares clear and appropriate scopes of work. Supervises establishment of subcontracts and ensures timely and successful subcontractor performance. Effectively supervises, trains, and enhances the capabilities of peers and subordinates. Demonstrates leadership skills by taking initiative, motivating, and helping others, sharing pertinent knowledge, emphasizing teamwork, and providing feedback. Proactively and creatively adapts to new work-related challenges. Maintains a highly professional image in all work-related activities. Registration with the Register of Professional Archaeologists (RPA) is a plus, as is involvement with professional organizations and institutions. Working familiarity with GIS/GPS programs such as Google Earth, ArcGIS, ArcMap, and use of .kml and .kmz files Expertise in MS Word, Excel, and Adobe Acrobat with familiarity in MS Access Reliable transportation to travel to project sites and meetings as needed. Familiarity with Deltek Vision is a plus. Education and Experience Bachelor of Science/Arts degree in Archaeology, or Architectural History. M.A. preferred. Minimum of 5 years' experience as a professional Archaeologist (SOI Qualified) Experience supervising laboratory and/or field crews is a plus Expertise in California Archaeology and general knowledge of the other Cultural Resources disciplines Familiarity with information resources in the scientific community, including other archaeologists, college and university programs, research centers and libraries, and data repositories. Expertise with sections relating to cultural resources in the California Environmental Quality Act (CEQA), the California Public Resources Code (PRC), the National Environmental Policy Act (NEPA), the Section 106 of the National Historic Preservation Act, the Archaeological Resources Protection Act (ARPA), and the Native American Graves Protection and Repatriation Act (NAGPRA), Understands field work, consultation, and reporting requirements specifics for various lead agencies including, but not limited to: local city and county lead agencies under CEQA; state lead agencies such as California Department of Transportation (Caltrans); and federal lead agencies such as United States Army Corps of Engineers (USACE), Federal Aviation Administration (FAA), Federal Communications Commission (FCC), Bureau of Land Management (BLM), and Bureau of Reclamation (USBR) Work Environment The position operates in a dynamic and highly collaborative working environment. FCS is dedicated to providing our staff the opportunity to elect remote, hybrid home/office as well as office location options. This role routinely uses standard office equipment and often requires field work in the form of records searches, pedestrian site surveys, archaeological testing, and data recovery. Physical Demands The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. While performing the duties of this job, the employee is regularly required to talk and hear; have hand/finger dexterity; and reach with hands and arms. The employee will spend extended periods of time in front of a computer/laptop. Specific vision abilities required by this job include close vision, distance vision, and ability to adjust focus. Compliance with all ADECi & FCS Travel and Workspace Policies that align with the CDC, local, state, and federal guidelines must be followed and upheld. Salary Range: $ $80,000 - 119,000 We offer competitive salaries based on experience and education. Our great comprehensive benefits also include personal and professional development opportunities. If you want to work in a collaborative, creative work environment where you can provide meaningful contributions while being challenged to grow on the job, then you are encouraged to apply! Competitive, progressive benefits, including Example: Full-time, regular employee Up to 100% employer paid premiums employee medical (with buy-up options) and up to 55% coverage for eligible dependent(s) Up to 80% employer-paid dental and vision covered premiums for employees. Eligible dependent coverage also available. Employer sponsored Group Life and AD&D insurance with discounted voluntary coverage also available Employer covered Short- & Long-Term Disability insurance Employee Assistance & Wellness Programs (EAP) 401(k) & Roth retirement savings accounts (see HR department for details on contributions and exclusions) Pet insurance discounts Volunteer programs, committees, and opportunities Mentorship program and Work/Life Balance initiatives *All benefits are subject to eligibility and may be changed at any time by the Company. Information Security Adhering to all policies, guidelines, and procedures pertaining to the protection of information of the organization, employees must maintain confidentiality of all sensitive information to which they are given access. They are also responsible for reporting actual or suspected events or incidents, including vulnerabilities or breaches, that may affect the confidentiality, integrity, and availability of information to members of the Management Team. Mutual Respect is fundamental. Fundamental to our teams. Fundamental to our clients. Fundamental to the communities we serve and live in. Fundamental to the landscapes we work within. We need you and your unique talents, history, and background to become the Company we aspire to be. We insist upon a culture of common respect, expect transparency, and celebrate the fundamental value and dignity of all individuals. Our mutual equality as humans is the path to diverse and innovative collaboration. We cultivate integrity, driving us to growth, and allowing us to achieve more together than we could ever hope to as individuals.
    $80k-119k yearly Auto-Apply 13d ago
  • Sr. Bioinformatics Scientist II

    Fulgent Genetics, Inc. 4.2company rating

    Principal research scientist job in El Monte, CA

    About Us Founded in 2011, Fulgent has evolved into a premier, full-service genomic testing company built around a foundational technology platform. Through our diverse testing menu, Fulgent is focused on transforming patient care in oncology, anatomic pathology, infectious and rare diseases, and reproductive health. We believe that by providing a wide range of effective, flexible testing options in conjunction with best-in-class service and support, we can redefine the way medicine is managed for patients and clinicians alike. Since integrating with our therapeutic development business, Fulgent is also developing drug candidates for treating a broad range of cancers using a novel nanoencapsulation and targeted therapy platform. By merging our fields of expertise, we aim to become a fully integrated precision medicine company. Summary of Position As a Senior Bioinformatics Scientist II, you will collaborate in cross-functional teams to design, implement and continually improve advanced computational pipelines for high-throughput analysis of multiple types of NGS data. You will work independently in refining methodologies for data analysis, processing, visualization and storage. You will also be assigned leadership roles in projects with mentor responsibility to junior members of the team. You will strive to maximize efficiency, quality, reliability and customer usability and satisfaction. Key Job Elements Research and Development Investigate and refine available algorithms, methods and data sources. Work independently to define, prioritize and complete objectives to meet company goals. Make recommendations for pipeline component improvements, or new pipelines. Write SOPs for new or updated pipeline components, or new pipelines. Write specifications for implementation by software developers. Oversee pipeline development and integration. Production and Customer Support Investigate and resolve analysis and pipeline production issues. Review client projects for compatibility with current pipelines, make recommendations and implement customizations as needed. Oversee sequencing service projects, ensuring timely processing, quality results and client satisfaction. Support software and LIMS developers in automation efforts. Perform specialized analyses as needed for specific projects. Keep up-to-date with current best practices and emerging methods. Treat data with a high level of integrity and ethics. Data Maintenance Investigate available annotation and reference data sources. Validate and deploy/update selected data sources. Write reports detailing validation/update methodology and results. Write SOPs for updating existing or new data sources. Validation Develop appropriate procedures for testing and validation of new or updated pipelines or pipeline components. Document and maintain data used for testing and validation. Write validation reports detailing validation methodology and results. Knowledge/Experience * Ph.D. degree from an accredited institution in Bioinformatics, Biostatistics or related field. * 10+ years of experience in a related scientific discipline (Bioinformatics preferred). * Demonstrated mastery of Fulgent specific methods and processes. * Experience analyzing multiple types of next-generation sequencing (NGS) data * Expertise with statistics for big data analysis and multiomics data integration. * Expert level hands-on skills in bioinformatics databases and tools. * Expert level in relevant programming languages, preferably Scala, Java, Python, and Bash. * Must enjoy working in a multi-disciplinary and collaborative environment. * Ability to troubleshoot both individually and as part of a team. * Excellent oral and written skills with the ability to communicate in an open, transparent, timely and consistent manner. * Experience in team software development and integration projects is a plus. Technical Leadership: * Provide technical leadership to the team * Be the mentor for junior team members. Supervisory Responsibilities * None Reports To * Director of Bioinformatics Environment Fulgent Therapeutics LLC is an Equal Employment Opportunity Employer. The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodations may be made to enable qualified individuals with disabilities to perform the essential functions. The term "qualified individual with a disability" means an individual with a disability who, with or without reasonable accommodation, can perform the essential functions of the position. For California residents, please see the link below to access our CCPA Privacy Notice. CCPA Privacy Notice for California Residents ******************************* Please note that Fulgent (and its affiliated companies, including Inform Diagnostics and CSI Laboratories) does not accept unsolicited information and/or resumes from search firms or agencies for our job postings. Search firms or agencies without an applicable contract and/or express approval to recruit for the role in question - that choose to submit a resume or client information to our career page or to any employee of Fulgent - will not be eligible for payment of any fee(s), and any associated shared data will become the property of Fulgent.
    $80k-131k yearly est. 29d ago
  • Scientist I (Tuesday to Saturday) - Eurofins Environment Testing - Pomona, CA

    Eurofins Horti

    Principal research scientist job in Pomona, CA

    Eurofins Scientific is a network of independent companies providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins laboratories work to ensure the products they supply are safe, their ingredients are authentic, and labelling is accurate. Eurofins is dedicated to delivering testing services that contribute to the health and safety of society and the planet, and to its corporate responsibility to protect the environment and ensure diversity, equity, and inclusion across the entire network of Eurofins companies. With over 50 laboratories and more than 40 service centers nationwide, Eurofins Environment Testing provides full-service environmental analysis across all 50 states. Our network supports public and private clients-including DoD, DOE, and municipalities-through robust logistics and continuous investment in people, technology, and infrastructure. We offer comprehensive testing for air, water, soil, sediment, tissue, and waste, covering a wide range of analytes including PFAS, metals, VOCs/SVOCs, dioxins/furans, radiochemicals, and more. Job Description EUROFINS EATON ANALYTICAL has a Scientist I opening at our Pomona Laboratory in our Organic Prep department. This is a regular full time position, 40 hrs/week. The Scientist I is responsible for routine analytical procedures in our laboratory. Duties include: Routine sample preparation of water samples by various written EPA and Standard Methods procedures Data entry and written documentation Performing routine instrument maintenance Preparation of reagents and standards Other general laboratory related duties as assigned May include regular late shift and/or weekend duties Qualifications Minimum BS degree in chemistry or other related science field with 1 - 2 years of laboratory experience. Must be available to work overtime including weekends. Excellent math and computer skills Excellent written and communication skills Excellent attention to details Ability to work well independently as well as in a team environment Authorization to work in the United States indefinitely without restriction or sponsorship Professional working proficiency in English is a requirement, including the ability to read, write and speak in English. Additional Information This role will be a full-time role, Tuesday to Saturday from 8 am to 5 pm with overtime and weekends as needed. Compensation Range: $22 - $24 / hour (DOE). Candidate within a commutable distance to Pomona, CA are encouraged to apply. Eurofins Environment Testing (USA) provides a compensation range for informational purposes, the actual base salary may vary based upon, but not limited to, relevant experience and skill set, base salary of internal peers, business sector, and geographic location. As a Eurofins employee, you will become part of a company that has received national recognition as a great place to work. We offer excellent full-time benefits including comprehensive medical coverage, life and disability insurance, 401(k) with company match, paid holidays, paid time off, and dental and vision options. To learn more about Eurofins, please explore our website ****************** We support your development! Do you feel you don't match 100% of the requirements? Don't hesitate to apply anyway! Eurofins companies are committed to supporting your career development. We embrace diversity! Eurofins network of companies believe in strength and innovation through diversity, being an Equal Opportunity Employer. We prohibit discrimination against employees or applications based on gender identity and/or expression, race, nationality, age, religion, sexual orientation, disability, and everything else that makes employees of Eurofins companies unique. Sustainability matters to us! We are well on our way to achieving our objective of carbon neutrality by 2025, through a combination of emission reduction and compensation initiatives. We encourage our laboratory leaders to make sustainable changes at their local level, and in addition to their initiatives we also count on our dedicated carbon reduction team to help us to achieve this goal! Find out more in our career page: ***************************** Eurofins USA Environment Testing is a Disabled and Veteran Equal Employment Opportunity employer.
    $22-24 hourly 13h ago
  • Senior Applied AI Scientist

    Cisco 4.8company rating

    Principal research scientist job in Irvine, CA

    **Meet the Team** Splunk, a Cisco company, is building a safer, more resilient digital world with an end‑to‑end, full‑stack platform designed for hybrid, multi‑cloud environments. Join the Foundational Modeling team at Splunk, where we advance the state of AI for high‑volume, real‑time, multi‑modal machine‑generated data - including logs, time series, traces, and events. We combine deep AI research expertise with the scale and operational excellence of Splunk and Cisco's global engineering capabilities. Our work spans networking, security, observability, and customer experience - designing and deploying foundation models that enhance reliability, strengthen security, prevent downtime, and deliver predictive insights across Splunk Observability, Security, and Platform at enterprise scale. You'll be part of a culture that values technical excellence, impact‑driven innovation, and cross‑functional collaboration - all within a flexible, growth‑oriented environment. **Your Impact** + Lead the research, design, and deployment of large‑scale foundation models for machine‑generated data - primarily time series, augmented with logs traces, and events. + Optimize distributed training and inference pipelines to maximize accuracy, performance, and efficiency at scale. + Work closely with engineering, product, and data science to ensure solutions meet defined technical requirements and deliver tangible business impact. + Mentor team members and contribute directly to model architecture reviews, experimental design, and production rollout processes. + Stay current with AI/ML developments and integrate relevant advancements into ongoing projects and technical plans. **Minimum Qualifications:** + PhD in Computer Science, or related quantitative field, plus 1+ years of industry research experience. + Proven track record in at least one of the following areas: large language modeling for both structure and unstructured data, deep learning‑based time series modeling, advanced anomaly detection, and multi-modality modeling. + Solid proficiency in Python and deep learning frameworks (e.g., PyTorch, TensorFlow) + Experience translating research ideas into production systems. **Preferred Qualifications:** + Deep Learning for Time Series & Forecasting - Proven expertise designing and deploying architectures such as temporal transformers, temporal convolutional networks, and spatial‑temporal models. + Advanced Anomaly Detection - Experience creating robust, scalable approaches (statistical, deep learning, or hybrid) for high‑volume, real‑time time series data. + Multi‑Modal AI Modeling - Strong track record fusing logs, time series, traces, tabular data, and graphs for foundation models tackling complex operational insights. + Probabilistic Forecasting & Uncertainty Quantification - Skills in Bayesian deep learning and probabilistic models to capture and communicate predictive uncertainty. + Large‑Scale Training & Optimization - Experience optimizing model architectures, distributed training pipelines, and inference efficiency to minimize cost and latency while preserving accuracy. + MLOps & Continuous Learning - Fluency in automated retraining, drift detection, incremental updates, and production monitoring of ML models. + Strong Research Track Record - Publications in top AI/ML conferences or journals (e.g., NeurIPS, ICML, ICLR, AAAI, CVPR, ACL, KDD) demonstrating contributions to state‑of‑the‑art methods and real‑world applications. **Why Cisco?** At Cisco, we're revolutionizing how data and infrastructure connect and protect organizations in the AI era - and beyond. We've been innovating fearlessly for 40 years to create solutions that power how humans and technology work together across the physical and digital worlds. These solutions provide customers with unparalleled security, visibility, and insights across the entire digital footprint. Fueled by the depth and breadth of our technology, we experiment and create meaningful solutions. Add to that our worldwide network of doers and experts, and you'll see that the opportunities to grow and build are limitless. We work as a team, collaborating with empathy to make really big things happen on a global scale. Because our solutions are everywhere, our impact is everywhere. We are Cisco, and our power starts with you. **Message to applicants applying to work in the U.S. and/or Canada:** The starting salary range posted for this position is $174,500.00 to $226,500.00 and reflects the projected salary range for new hires in this position in U.S. and/or Canada locations, not including incentive compensation*, equity, or benefits. Individual pay is determined by the candidate's hiring location, market conditions, job-related skillset, experience, qualifications, education, certifications, and/or training. The full salary range for certain locations is listed below. For locations not listed below, the recruiter can share more details about compensation for the role in your location during the hiring process. U.S. employees are offered benefits, subject to Cisco's plan eligibility rules, which include medical, dental and vision insurance, a 401(k) plan with a Cisco matching contribution, paid parental leave, short and long-term disability coverage, and basic life insurance. Please see the Cisco careers site to discover more benefits and perks. Employees may be eligible to receive grants of Cisco restricted stock units, which vest following continued employment with Cisco for defined periods of time. U.S. employees are eligible for paid time away as described below, subject to Cisco's policies: + 10 paid holidays per full calendar year, plus 1 floating holiday for non-exempt employees + 1 paid day off for employee's birthday, paid year-end holiday shutdown, and 4 paid days off for personal wellness determined by Cisco + Non-exempt employees** receive 16 days of paid vacation time per full calendar year, accrued at rate of 4.92 hours per pay period for full-time employees + Exempt employees participate in Cisco's flexible vacation time off program, which has no defined limit on how much vacation time eligible employees may use (subject to availability and some business limitations) + 80 hours of sick time off provided on hire date and each January 1st thereafter, and up to 80 hours of unused sick time carried forward from one calendar year to the next + Additional paid time away may be requested to deal with critical or emergency issues for family members + Optional 10 paid days per full calendar year to volunteer For non-sales roles, employees are also eligible to earn annual bonuses subject to Cisco's policies. Employees on sales plans earn performance-based incentive pay on top of their base salary, which is split between quota and non-quota components, subject to the applicable Cisco plan. For quota-based incentive pay, Cisco typically pays as follows: + .75% of incentive target for each 1% of revenue attainment up to 50% of quota; + 1.5% of incentive target for each 1% of attainment between 50% and 75%; + 1% of incentive target for each 1% of attainment between 75% and 100%; and + Once performance exceeds 100% attainment, incentive rates are at or above 1% for each 1% of attainment with no cap on incentive compensation. For non-quota-based sales performance elements such as strategic sales objectives, Cisco may pay 0% up to 125% of target. Cisco sales plans do not have a minimum threshold of performance for sales incentive compensation to be paid. The applicable full salary ranges for this position, by specific state, are listed below: New York City Metro Area: $199,700.00 - $292,800.00 Non-Metro New York state & Washington state: $174,500.00 - $260,500.00 * For quota-based sales roles on Cisco's sales plan, the ranges provided in this posting include base pay and sales target incentive compensation combined. ** Employees in Illinois, whether exempt or non-exempt, will participate in a unique time off program to meet local requirements. Cisco is an Affirmative Action and Equal Opportunity Employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, gender, sexual orientation, national origin, genetic information, age, disability, veteran status, or any other legally protected basis. Cisco will consider for employment, on a case by case basis, qualified applicants with arrest and conviction records.
    $199.7k-292.8k yearly 28d ago
  • Staff Scientist - Precision Oncology of Gastrointestinal Cancers

    Aa067

    Principal research scientist job in Monrovia, CA

    Staff Scientist - Precision Oncology of Gastrointestinal Cancers - (10032520) Description Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research. Led by Dr. Ajay Goel, Professor and Founding Chair of the Department of Molecular Diagnostics and Experimental Therapeutics, our multidisciplinary research group comprises basic researchers, gastroenterologists, surgeons, oncologists, and bioinformaticians, undertaking several collaborative projects involving large international consortia. This position has the potential to become tenure-track upon the receipt of grant funding lasting 3-5 years from a federal agency. Our research focuses on translational studies of the genomic and epigenomic characterization of various gastrointestinal cancers (GI), including colorectal, pancreatic, gastric, esophageal, and hepatocellular cancers. Our group performs cutting-edge research in GI oncology, is very productive, and publishes in high-impact journals such as Nature Cancer, Nature Communications, Nature Biotechnology, Nature Reviews Gastroenterology and Hepatology, New England Journal of Medicine, CA: A Journal for Clinicians, Gastroenterology, Cancer Cell, PNAS, JAMA Oncology, JNCI, Cancer Research, Clinical Cancer Research, , Annals of Surgery, etc. For more information on Dr. Goel's research, please visit here. If you are passionate about some of the following things, we are working on this may be the perfect opportunity:· Development of cell-free DNA (mutation and methylation), RNA, and exosomal-based liquid assays for early cancer detection, prognosis, and predictive responses to chemotherapies and targeted drugs. · Studying the genetic and epigenetic basis of GI cancers (e. g. , aberrant DNA methylation, histone modifications, and non-coding RNAs). · Understanding the biological implications of gut microbiome and its translational application in gastrointestinal cancers· The genetic basis of early-onset colorectal cancer (EO-CRC) and familial/hereditary colorectal cancer. · The role of extracellular vesicles/exosomes in cancer pathogenesis and their role as disease biomarkers. · The role of the tumor microenvironment, stem cells, immune regulation, and identification of novel targeted therapies. · Cancer prevention and adjunctive role of natural and integrative therapy approaches. As a successful candidate, you will be:· Developing liquid biopsy biomarkers for cancer diagnosis, prognosis, and therapy response prediction. · Investigating the epigenetic basis of GI cancers, such as aberrant DNA methylation, histone modifications, and non-coding RNAs. · Exploring the genetics of early-onset and familial/hereditary colorectal cancers. · Studying the tumor microenvironment, stem cells, immune regulation, and identifying targeted therapies. · Investigating extracellular vesicles/exosomes in cancer pathogenesis and as disease biomarkers Qualifications Your qualifications should include:· PhD, MD, or MD/PhD, with a strong background and profound knowledge in the field of oncology, cancer biology, immunology, or immunotherapy. · Prior molecular, cancer biology, and/or translational research experience and evidence of project development and supervision of post-doctoral fellows and technical staff. · Evidence of scientific rigor and excellence as documented by high-impact peer-reviewed publications, as a first/lead author. · Evidence for obtaining successful funding from various foundations or other extramural resources. · Documented evidence of mentoring post-docs, research associates, and others in a research laboratory environment. City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location. City of Hope is an equal opportunity employer. To learn more about our Comprehensive Benefits, please CLICK HERE. Primary Location: United States-California-MonroviaJob: ResearchWork Force Type: OnsiteShift: DaysJob Posting: Oct 14, 2025Minimum Hourly Rate ($): 38. 674337Maximum Hourly Rate ($): 127. 693000
    $84k-139k yearly est. Auto-Apply 16h ago

Learn more about principal research scientist jobs

How much does a principal research scientist earn in Highland, CA?

The average principal research scientist in Highland, CA earns between $104,000 and $239,000 annually. This compares to the national average principal research scientist range of $87,000 to $184,000.

Average principal research scientist salary in Highland, CA

$157,000
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