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Principal research scientist jobs in Hyde Park, NY - 31 jobs

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  • Scientist, Pre-Formulation & Drug Product Development

    Tundra Technical Solutions

    Principal research scientist job in Ridgefield, CT

    This role supports drug product development activities across early and clinical-stage programs, with primary responsibility for formulation development, clinical manufacturing support, and technology transfer. The position works closely with internal CMC teams and external partners to ensure high-quality, phase-appropriate drug product delivery in compliance with GxP and regulatory requirements. The role is hands-on and execution-focused, contributing technical expertise across small molecule programs with exposure to oligonucleotides and advanced modalities. Key Responsibilities Support delivery of drug product development activities, including: Pre-formulation and formulation development Process development and tech transfer Phase-appropriate stability studies GMP clinical trial material (CTM) manufacturing Contribute to drug substance/drug product supply activities, including preparation and review of GxP documentation and technical summaries. Support regulatory document authoring and review (e.g., IND, IMPD, NDA sections) and assist in responses to health authority questions. Collaborate with external CROs, CMOs, and CDMOs on formulation development, manufacturing execution, and technology transfer. Review and approve technical reports, manufacturing documentation, and development data for accuracy and compliance. Work cross-functionally with CMC, Quality, Regulatory, and Development teams to support program execution. Ensure compliance with applicable GMP, GLP (as applicable), safety, quality, and corporate policies. Present scientific data internally and contribute to technical discussions and decision-making. Required Experience & Skills Hands-on experience in: Preclinical formulation and pre-formulation characterization Drug product formulation and process development (QbD) Tech transfer and cGMP manufacturing support Experience developing phase-appropriate drug product and supporting clinical supply manufacturing for small molecules and/or oligonucleotides. Experience working with and coordinating activities across external CROs and CDMOs/CMOs. Familiarity with ICH quality guidelines and FDA/EU drug manufacturing regulations. Ability to review and approve GxP documentation and technical reports. Strong written and verbal communication skills, including technical presentations to scientific and cross-functional audiences. Ability to work effectively in cross-functional and matrixed team environments. Nice to Have Experience with oligonucleotide formulation and process development. Exposure to injectable peptides or advanced modalities. Prior experience contributing to publications or external scientific presentations. Education Master's degree in Chemistry, Chemical Engineering, or Pharmaceutical Sciences with 7+ years of relevant industry experience OR PhD in a related discipline with 5+ years of relevant industry experience in drug product development
    $79k-106k yearly est. 4d ago
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  • In Vitro Scientist

    Fladger Associates

    Principal research scientist job in Ridgefield, CT

    Responsibilities: Excellent employment opportunity for a Scientist II in the Ridgefield, CT area. Fully onsite Initiates and completes routine in vitro studies in an independent, efficient, and timely manner, with minimal supervision. Interprets the outcome of those experiments and proposes appropriate follow-up; troubleshoots effectively. Assists in the design and execution of non-routine cell-based in vitro and biochemical assays; conducts exploratory experiments with minimal supervision. Performs literature searches and extracts relevant information from literature and published protocols. Independently operates and is responsible for lab equipment; troubleshoots effectively. Communicates their own work effectively orally and in writing; contributes to writing protocols, procedures, and technical reports; provides input for scientific reports. Reports and treats data with a high level of integrity and ethics. Maintains accurate and up-to-date electronic lab notebooks. Complies with applicable regulations, performing all work in a safe and compliant manner; maintains proper records in accordance with Standard Operating Procedures and policies. Experience: Master's Degree or Bachelor's Degree with 3+ years experience in related scientific discipline; pharmaceutical, biotechnology or CRO experience is highly desirable; non-PhD applicant required. Experience in aseptic animal tissue culture techniques and basic molecular biology techniques including nucleic acid extraction, RT-PCR, Western Blot, ELISA, transfection is required. Experimental design, execution, and interpretation in these areas will be required. Proven problem-solving ability and eagerness to learn. Ability to evaluate new technologies and assist in incorporating them into our research. Written and verbal communication skills: concise and accurate reporting of technical data and information Proficiency with computers and data analysis software such as Microsoft Excel and GraphPad Prism. Ability and willingness to work effectively in a highly collaborative environment. Required Skills ASEPTIC ANIMAL TISSUE CULTURE TECHNIQUES BASIC MOLECULAR BIOLOGY TECHNIQUES
    $73k-106k yearly est. 2d ago
  • Scientist II-- PATDC5708325

    Compunnel Inc. 4.4company rating

    Principal research scientist job in Ridgefield, CT

    Initiates and completes routine in vitro studies in an independent, efficient, and timely manner, with minimal supervision. Interprets the outcome of those experiments and proposes appropriate follow-up; troubleshoots effectively. Assists in the design and execution of non-routine cell-based in vitro and biochemical assays; conducts exploratory experiments with minimal supervision. Performs literature searches and extracts relevant information from literature and published protocols. Independently operates and is responsible for lab equipment; troubleshoots effectively. Communicates their own work effectively orally and in writing; contributes to writing protocols, procedures, and technical reports; provides input for scientific reports. Reports and treats data with a high level of integrity and ethics. Maintains accurate and up-to-date electronic lab notebooks. Complies with applicable regulations, performing all work in a safe and compliant manner; maintains proper records in accordance with Standard Operating Procedures and policies. Skills: Experience in aseptic animal tissue culture techniques and basic molecular biology techniques including nucleic acid extraction, RT-PCR, Western Blot, ELISA, transfection is required. Experimental design, execution, and interpretation in these areas will be required. oven problem-solving ability and eagerness to learn. Ability to evaluate new technologies and assist in incorporating them into our research. Written and verbal communication skills: concise and accurate reporting of technical data and information Proficiency with computers and data analysis software such as Microsoft Excel and GraphPad Prism. Ability and willingness to work effectively in a highly collaborative environment. Education: Master's degree or bachelor's Degree with 3+ years' experience in related scientific discipline; pharmaceutical, biotechnology or CRO experience is highly desirable
    $87k-121k yearly est. 2d ago
  • SR Principal/ Principal Scientist, In Vitro Translational Rheumatology

    Boehringer Ingelheim 4.6company rating

    Principal research scientist job in Ridgefield, CT

    A key scientific leader of the Immunology and Respiratory Translational Biology Group, the **Principal** / **Sr. Principal Scientist** is responsible for establishing the scientific know-how and experimental approach in rheumatology to support the positioning of discovery molecules within this disease space. As a laboratory leader, the incumbent will direct a team of scientists to develop and apply complex in vitro translational assays across discovery and development projects. Candidates must have a strong knowledge in immunology with drug discovery experience in rheumatological diseases and a proven track record of productivity both independently (with minimal supervision) and within a team setting in a matrix and collaborative environment. As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development and delivery of our products to our patients and customers. Our global presence provides opportunity for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the companies´ success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, mobility, networking and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim´s high regard for our employees **Duties & Responsibilities** + Lead and guide positioning of molecules in the disease area of Rheumatology by generating a scientific translational data package to support disease selection. Serve as the rheumatology disease area expert in Research by demonstrating up-to-date knowledge of rheumatological diseases including pathogenesis, standard of care, unmet need, and using this knowledge as the basis for developing translational assay systems. + Independently proposes, design and performs scientific experiments with a predefined goal including developing new methodologies, protocols and or test procedures that contribute to core group/research goals and reflect expert knowledge; Direct and oversee experimental design and results of technicians and junior level scientists. + Assumes leadership role for either project teams and/or acts as a translational biology representative on multiple project teams and contributes to overall program goals. + Prepares clear technical reports, publications and oral presentations. Independently communicate results in the form of reports and/ or presentations; Deliver updates to senior level management in context of overall project goals. + Build strong connections with external key opinion leaders in the field of rheumatology, Incorporate feedback and scientific insights into projects and experimental plans. Remain abreast of scientific literature. + Work collaboratively within department, and across the Innovation Unit, including with Experimental Medicine colleagues and Medicine. + Assumes responsibility for direct reports as needed including recruiting, managing, mentoring and developing scientific staff. + Complies with all applicable regulations; Ensures that work performed in area of responsibility is conducted in a safe and compliant manner; Maintains proper records in accordance with SOPs and policies. + Contributes to departmental administration; Demonstrates fiscal responsibility with respect to cost of experiments, technology, external collaborations, and travel. **Requirements** **Requirements for BOTH Levels:** + A demonstrated track record of independent research and peer-reviewed publications in areas of immunology. Comprehensive knowledge of Rheumatologic diseases, including understanding of the T and B cell biology and interaction to other components of the tissue microenvironment. + Strong understanding of immunology, with robust in vitro experimental skills. Prior hands-on experience with developing novel in vitro complex cellular models to assess the effects of novel therapeutic concepts. Expertise in establishing Rheumatologic-relevant culture systems is a plus. + Strong problem-solving skills and sound judgment to accelerate strategic and project decision-making. + Team player with strong verbal, presentation, and written communication skills, with the ability to propose, articulate, evaluate and defend scientific ideas and data. + Ability to mentor, develop and lead a group of scientists to deliver high quality data to contribute to overall program goals. Be accountable for the effective performance of the individuals. + The ability to prioritize responsibility and be comfortable with changing direction and/or priorities. + Appropriate level of understanding of applicable regulations. + Ability to communicate effectively both orally and in writing in an interdisciplinary environment. + Previous supervisory experience. **Principal Scientist:** + Ph.D. Degree or equivalent 5+ years related experience in a related field or equivalent **Sr Principal Scientist:** + Ph.D. from an accredited institution, or equivalent in relevant field, with seven-plus (7+) years of experience in addition to experience in lab management **Compensation:** This position, Principal Scientist, offers a base salary typically between $140,000.00 and $222,000.00. The position may be eligible for a role specific variable or performance based bonus and or other compensation elements. For an overview of our benefits please click here. (***************************************************************** **Desired Skills, Experience and Abilities** + Previous supervisory experience preferred All qualified applicants will receive consideration for employment without regard to a person's actual or perceived race, including natural hairstyles, hair texture and protective hairstyles; color; creed; religion; national origin; age; ancestry; citizenship status, marital status; gender, gender identity or expression; sexual orientation, mental, physical or intellectual disability, veteran status; pregnancy, childbirth or related medical condition; genetic information (including the refusal to submit to genetic testing) or any other class or characteristic protected by applicable law.
    $140k-222k yearly 60d+ ago
  • R&D - Senior Researcher S&A

    Duracell 4.8company rating

    Principal research scientist job in Bethel, CT

    The primary functions of this role are to: 1) execute established Raw Material, In Process Materials, Finished Product, and Failure Analysis methods to enable R&D initiatives and resolve technical challenges. 2) recommend and contribute to the optimization/modification of existing methods and establishment of new ones to meet evolving R&D needs and 3) over time develop understanding of chemistries, materials and process transformations to create greater value and/or eliminate wasted effort/cost. The individual will be expected to use a variety of Battery Life Test Systems, Safety Test Systems, environmental chambers, shock and vibration testers, meters, gauges, power supplies, and various test lab management tools. Responsibilities/Duties: * Proficient in ability to perform high quality execution of established methods to achieve desired goals or results. * Methods and measurements will include but not limited to: * Battery internal gas measurements using a manometer or pressure transducer approach. * Leakage assessment visually and/or by using automated extraction method. * Pre and post-test battery electrical measurements. * ANSI and IEC standards for primary chemistry cells * Proficient in performing against multiple projects in parallel. * Mentor and train junior employees on established methods and new ways of thinking. * proficient in analyses (statistical, if needed) of data to uncover new findings from R&D work. * Use Lab Information Management system to execute daily scheduled tasks and enter method results. * Monitor environmental chambers and lab temperatures. * Comply with the lab's accreditation, operation, and EH&S requirements * Provide insights from "project level" R&D work. * ability to identify and improve (streamline or increase value) methods to create greater value and/or eliminate wasted effort/cost. Qualifications & Skill Requirements: * Degree in scientific discipline. Chemistry or engineering preferred. * Experience working in a lab environment and knowledge of safe lab practices. * Strong attention to detail and ability to follow procedures to maintain a safe working environment is required * Be able to lift 30 lbs. * Ability to work independently with a passion towards excellence and producing consistent quality and accurate results. Duracell is the world's leading manufacturer and marketer of high-performance alkaline batteries, complemented by a portfolio of high quality, market leading specialty, rechargeable and professional batteries. Duracell's products power numerous critical professional devices across the globe such as heart rate monitors, defibrillators, telemetry devices, smoke detectors, fire alarms, automated valves and security systems. As the leader in the professional power category, Duracell has a rich history of innovation, continuously introducing batteries that are smaller, thinner, with more energy and longer lasting than competitive brands. Since March 2016, Duracell has found its permanent home within Berkshire Hathaway (ranked #4 World's Most Admired Companies by Fortune Magazine and #3 in the Fortune 500), and will continue to focus on sustainable growth, industry-leading innovation while creating long-term value for our customers and consumers. At Duracell, integrity, end-to-end accountability across all levels, fast decision-making and a "can do" attitude is highly valued.
    $106k-131k yearly est. Auto-Apply 49d ago
  • Scientist II

    Mindlance 4.6company rating

    Principal research scientist job in Ridgefield, CT

    Studies the basic principles of plant and animal life and the effects of varying environmental and physical conditions such as radioactivity or pollution. Studies reactions of plants, animals, and marine species to parasites, bacteria, pharmaceuticals and chemicals. • Performing cell assay development and NTC studies on Client targets . • Skills: • Familiar with a variety of the fields concepts, practices, and procedures. • Education: • Bachelor's Degree • Cell biology and molecular biology skills a plus • Languages: • English Read Write Speak • Education: Bachelor's Degree • Skills: Familiar with a variety of the fields concepts, practices, and procedures.
    $75k-107k yearly est. 3d ago
  • Scientist IV

    Us Tech Solutions 4.4company rating

    Principal research scientist job in Ridgefield, CT

    US Tech Solutions is a global staff augmentation firm providing a wide-range of talent on-demand and total workforce solutions. To know more about US Tech Solutions, please visit our website ************************ We are constantly on the lookout for professionals to fulfill the staffing needs of our clients, sets the correct expectation and thus becomes an accelerator in the mutual growth of the individual and the organization as well. Keeping the same intent in mind, we would like you to consider the job opening with US Tech Solutions that fits your expertise and skillset. Job Description Duties: Perform dose formulation analysis under FDA GLPs for nonclinical studies. Provide dose formulation stability testing for GLP studies. Develop and validated analytical methods for doser formulation analysis. Assume responsibility for analytical support of nonclinical studies as contributing scientist/principal investigator working with BI nonclinical drug safety study directors and CRO scientists/study directors. Review laboratory notebooks and chromatographic data. Write analytical reports for inclusion in nonclinical study reports. Write dose formulation stability reports for GLP study support. Skills: Expertise in HPLC and analytical method development. Preferred experience in GLPs, Microsoft Office, Empower chromatographic data system. Qualifications Education: Bachelor's Degree and 7-10 years' experience in analytical chemistry/chromatography Additional Information Richha Saini Senior Clinical/Pharmaceutical Recruiter Tel: ************** Ext 7179 Direct: ************
    $70k-108k yearly est. 3d ago
  • In Vitro Scientist II

    System One 4.6company rating

    Principal research scientist job in Ridgefield, CT

    Job Title: In Vitro Scientist II Type: Contract Global Pharma company looking to hire experienced Scientist to join their growing team. Must bring a Master's Degree or Bachelor's Degree with 3+ years experience in molecular biology. Pharmaceutical, biotechnology or CRO experience is highly desirable. Responsibilities + Initiates and completes routine in vitro studies in an independent, efficient, and timely manner, with minimal supervision. Interprets the outcome of those experiments and proposes appropriate follow-up; troubleshoots effectively. + Assists in the design and execution of non-routine cell-based in vitro and biochemical assays; conducts exploratory experiments with minimal supervision. + Performs literature searches and extracts relevant information from literature and published protocols. + Independently operates and is responsible for lab equipment; troubleshoots effectively. + Communicates their own work effectively orally and in writing; contributes to writing protocols, procedures, and technical reports; provides input for scientific reports. + Reports and treats data with a high level of integrity and ethics. + Maintains accurate and up-to-date electronic lab notebooks. + Complies with applicable regulations, performing all work in a safe and compliant manner; maintains proper records in accordance with Standard Operating Procedures and policies. Requirements + Master's Degree or Bachelor's Degree with 3+ years experience in related scientific discipline; pharmaceutical, biotechnology or CRO experience is highly desirable; non-PhD applicant required. + Experience in aseptic animal tissue culture techniques and basic molecular biology techniques including nucleic acid extraction, RT-PCR, Western Blot, ELISA, transfection is required. Experimental design, execution, and interpretation in these areas will be required. + Proven problem-solving ability and eagerness to learn. Ability to evaluate new technologies and assist in incorporating them into our research. + Written and verbal communication skills: concise and accurate reporting of technical data and information + Proficiency with computers and data analysis software such as Microsoft Excel and GraphPad Prism. + Ability and willingness to work effectively in a highly collaborative environment. Benefits System One offers eligible employees health and welfare benefits coverage options, including medical, dental, vision, spending accounts, life insurance, voluntary plans, and participation in a 401(k) plan. Ref: #558-Scientific System One, and its subsidiaries including Joulé, ALTA IT Services, CM Access, TPGS, and MOUNTAIN, LTD., are leaders in delivering workforce solutions and integrated services across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible full-time employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan. System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.
    $72k-107k yearly est. 3d ago
  • Scientist II

    Lancesoft 4.5company rating

    Principal research scientist job in Ridgefield, CT

    Initiates and completes routine in vitro studies in an independent, efficient, and timely manner, with minimal supervision. Interprets the outcome of those experiments and proposes appropriate follow-up;troubleshoots effectively. Assists in the design and execution of non-routine cell-based in vitro and biochemical assays;conducts exploratory experiments with minimal supervision. Performs literature searches and extracts relevant information from literature and published protocols. Independently operates and is responsible for lab equipment;troubleshoots effectively. Communicates their own work effectively orally and in writing;contributes to writing protocols, procedures, and technical reports;provides input for scientific reports. Reports and treats data with a high level of integrity and ethics. Maintains accurate and up-to-date electronic lab notebooks. Complies with applicable regulations, performing all work in a safe and compliant manner;maintains proper records in accordance with Standard Operating Procedures and policies. Skills: Experience in aseptic animal tissue culture techniques and basic molecular biology techniques including nucleic acid extraction, RT-PCR, Western Blot, ELISA, transfection is required. Experimental design, execution, and interpretation in these areas will be required. Proven problem-solving ability and eagerness to learn. Ability to evaluate new technologies and assist in incorporating them into our research. Written and verbal communication skills: concise and accurate reporting of technical data and information Proficiency with computers and data analysis software such as Microsoft Excel and GraphPad Prism. Ability and willingness to work effectively in a highly collaborative environment. Education: Master s Degree or Bachelor s Degree with 3+ years experience in related scientific discipline;pharmaceutical, biotechnology or CRO experience is highly desirable;non-PhD applicant required. Skills and Experience The Skills and Experience match parameters for the candidate are parsed from the Duties, Skills, and Education. Required Skills ASEPTIC ANIMAL TISSUE CULTURE TECHNIQUES BASIC MOLECULAR BIOLOGY TECHNIQUES
    $84k-114k yearly est. 4d ago
  • Scientist I

    Steris 4.5company rating

    Principal research scientist job in Chester, NY

    At STERIS, we help our Customers create a healthier and safer world by providing innovative healthcare and life science product and service solutions around the globe. Responsible for the activities related to validation of sterilization processes across STERIS operating facilities. Activities include calibration of data collection systems, such as maintaining dosimeters and dosimetry equipment, measurement of dosimeters for report generation; operation, and data collection related to portable temperature/humidity sensors; coordinating with external laboratories for equipment calibrations and maintenance; coordinating with Customers for test sample processing and requalification studies; coordination and proper handling of product samples for transfer to outside laboratories for testing; and other routine tasks as directed by the immediate supervisor or manager. What You'll Do as a Scientist I Supports the conduct of scientific studies for investigation and validation purposes. Contributes to creating and maintaining valid sterilization processes in the medical device or pharmaceutical industry that comply to FDA regulations, ISO, AAMI, and ASTM standards. Acts as liaison between Customer and the facility leadership during Customer driven studies. Assists in statistical analysis of data, such as variation analysis, specific to the modality in use. Contributes to successful product processing by performing dosimeter calibrations or temperature/humidity sensor calibrations. Ensures all internal equipment is calibrated per procedure requirements and coordinates calibrations with external vendors. Ensures processes are maintained in a validated state by supporting periodic verifications and execution of revalidations or requalifications following changes. Contributes to safe and accurate processing by notifying management of any event, item or documentation that may have a concern in regard to regulatory or specification compliance, Customer product quality, or employee safety. Maintains a safe work environment by attending safety meetings with local facility, completing safety rounds, and tracking all hazardous materials as contained in the Safety Data Sheets. Communicates in an effective manner by utilizing accepted business practices in a courteous and professional manner providing timely and accurate responses and service oriented offers of assistance. Protects company confidential information by properly storing, retrieving and disseminating such information only to those authorized. Exhibits a commitment to the AST shared values of Customer Satisfaction and Continuous Improvement through ensuring defect-free workmanship, assisting others to meet the Customer's needs, searching for efficient and effective ways to reduce waste, being active and accountable for Customer satisfaction, and satisfying the Customer's needs with a sense of urgency. Contributes in a team effort by performing according to the guidelines outlined in the STERIS Code of Business Conduct, the GMP, Lean principles and other directives; supports the directives and decisions of higher level management and performs other duties as assigned. The Experience, Skills and Abilities Required Required Qualifications: Bachelor's degree in a scientific discipline or related field. Preferred Qualifications: Experience working in a regulated environment (e.g., GMP, GLP, or similar). Strong organizational skills with the ability to manage multiple tasks and priorities effectively. Demonstrated proactive approach to task management, ensuring timely completion of individual and team objectives. Ability to take initiative and maintain accountability for assigned responsibilities. Pay range for this opportunity is $55,250 to $65,000, dependent on experience and skillset. This position is eligible for bonus participation. Minimum pay rates offered will comply with county/city minimums, if higher than range listed. Pay rates are based on a number of factors, including but not limited to local labor market costs, years of relevant experience, education, professional certifications, foreign language fluency, etc. STERIS offers a comprehensive and competitive benefits portfolio. Click here for a complete list of benefits: STERIS Benefits Open until position is filled. STERIS is an Equal Opportunity Employer. We are committed to equal employment opportunity to ensure that persons are recruited, hired, trained, transferred and promoted in all job groups regardless of race, color, religion, age, disability, national origin, citizenship status, military or veteran status, sex (including pregnancy, childbirth and related medical conditions), sexual orientation, gender identity, genetic information, and any other category protected by federal, state or local law. We are not only committed to this policy by our status as a federal government contractor, but also we are strongly bound by the principle of equal employment opportunity.
    $55.3k-65k yearly 35d ago
  • Senior Fellowship 2025-2026

    Hamilton College 4.0company rating

    Principal research scientist job in Clinton, NY

    Each spring the Dean of the Faculty designates up to seven academically outstanding members of the junior class as Senior Fellows. Students in the junior year may become candidates by submitting a proposal for a senior year of independent study. The proposal usually grows out of earlier independent study courses and is framed in consultation with two faculty advisers of the student's choice. Senior Fellows are exempt from taking a normal course load in the conventional curriculum, and they need not complete concentration requirements; they may take such courses as are appropriate to their fellowship projects and their educational goals. A written thesis is required at the close of the fellowship year, along with a public lecture to the College community. Evaluation is made by the advisors and an examination committee. Although the proposal for a Senior Fellowship has no set length or format, a typical proposal is approximately 7 to 10 pages long. The proposal should include the following information: A. Reasons why you wish to do a Senior Fellowship. How would a senior fellowship year fit into your liberal arts education and/or career goals? Why would it be a more appropriate alternative to continued formal coursework and completion of your degree and concentration requirements? Is it a natural outgrowth of an experience or interest you have developed at Hamilton, of an experience abroad or elsewhere? B. Outline of the projected study. This should include (1) appropriate and detailed background information indicating your understanding of the problem or topic you wish you investigate; (2) the means by which you will accomplish your investigation; and (3) the significance of the undertaking. You should also explain how you will have access to the necessary materials, resources and expertise, either here at Hamilton or elsewhere, to enable you to do the project. Previous coursework experience with your principal or secondary advisors is also important in establishing the background preparation for your proposed project. C. An outline of your senior year. Explain what additional activities you expect to engage in: coursework, if any (we usually recommend at least one course per term); extracurricular activities; other activities related to your project (e.g. attending professional meetings, visiting labs or other facilities at other colleges, research at other libraries or resources). D. An explanation of how your work at Hamilton has achieved, or will achieve, the breadth of study which is a primary goal of a liberal arts education. This breadth might be fulfilled by your (1) having taken an unusually broad selection of courses in your first three years; (2) undertaking an interdisciplinary Senior Fellowship; (3) supplementing the Senior Fellowship with course work which increase the breadth of your overall program of study; or (4) some combination of the above. E. Any other information which you believe clarifies or strengthens your proposal for a Senior Fellowship year. F. An unofficial transcript. G. Letters of support provided separately by faculty members. Those faculty members who have agreed to be your primary and secondary advisors should indicate their willingness and ability to provide guidance for the year and speak to your strengths, your capabilities, and the likelihood that you will complete the Senior Fellowship successfully. In addition, you must submit a letter of support from a faculty member outside the discipline of your proposed fellowship, speaking more generally to your qualifications to be a Fellow. H. Please include a cover sheet on your proposal with the following information: Name Proposal Title Principal Advisor Secondary Advisor(s) Submit the completed proposal, including the supporting letters from three faculty members, to the Office of the Dean of Faculty through Interfolio by Tuesday, April 8, 2025. Your proposal will be read and evaluated by the Dean, the Academic Council, and the Director of the Senior Fellowship Program. Since the Council is a diverse group representing a variety of academic disciplines, whose members may not be familiar with your topic or methods of inquiry, please make sure your proposal is comprehensible to a non-specialist. If you have questions, please contact Professor Todd Franklin, Director of the Senior Fellowship Program, at *********************.
    $60k-69k yearly est. Easy Apply 60d+ ago
  • Scientist I - Preclinical Formulation

    Tundra Technical Solutions

    Principal research scientist job in Ridgefield, CT

    We're seeking a hands-on Scientist I / Formulation Technician to support a preclinical formulation team preparing dosing formulations for nonclinical studies. This is an execution-focused lab role ideal for someone who enjoys wet-lab work, structured processes, and working in a regulated environment. What You'll Do Prepare oral and parenteral dosing formulations for preclinical and toxicology studies Execute formulation prep for in-house studies and support early-stage programs Maintain batch records, formulation documentation, and study records Handle pharmaceutical materials, excipients, and test compounds per SOPs Support test item logistics, including inventory management and domestic/international shipments to CROs Coordinate with internal teams and external partners to meet study timelines Assist with GLP documentation, archiving, and lab compliance Support routine lab organization, inspections, and EHS compliance What We're Looking For Hands-on lab experience with formulation, chemistry, or pharmaceutical materials Comfortable working in a wet-lab environment Strong organization, documentation, and time-management skills Proficiency with MS Office (Excel, Word, PowerPoint, Teams) Team-oriented, proactive, and detail-focused Nice to Have Experience in a GLP or regulated lab environment (trainable) Exposure to preclinical or early-stage formulation Experience with LIMS systems (e.g., Pristima or similar) Prior CRO coordination or shipment logistics experience Education Bachelor's degree in Chemistry, Pharmaceutical Sciences, Biology, or related field (Master's a plus)
    $79k-115k yearly est. 2d ago
  • US_Principal Scientist, Human Genetics

    Boehringer Ingelheim 4.6company rating

    Principal research scientist job in Ridgefield, CT

    As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development and delivery of our products to our patients and customers. Our global presence provides opportunity for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the companies' success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, mobility, networking and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees. The focus of this role is to advance human genetics-driven drug discovery across multiple disease areas, including inflammatory and respiratory conditions, cardiorenal metabolic disorders, cancer immunology and others. In this role, the Principal Scientist brings deep hands-on expertise in performing standard genetic analyses (eg., GWAS, meta-analysis, QTL evaluation), using biobank-scale datasets and interpretation of results to contribute to strategic objectives. These objectives include elucidation of disease biology, understanding mechanism of action for therapeutic candidates, safety assessment, translational biomarker nomination and establishing proof of clinical concept. Additional responsibilities include contributions to nominating first-in-class novel therapeutic concepts rooted in human genetics evidence. Direct participation in analysis, results interpretation and clear communication of results to an audience with diverse expertise is required. At this level, significant responsibilities in project leadership and team mentorship are expected. **Duties & Responsibilities** + Partner with cross-functional teams to establish and advance therapeutic strategies, specifically contributing relevant evidence and innovative ideas from human genetics. + Contribute to analyses, and to building datasets and analytic capabilities as needed in partnership with the global human genetics team to address research needs that can be addressed with genetics. + Excel in strategic initiatives, offer insights and execute tasks at the level of a recognized subject matter expert. + Effectively lead, collaborate, and communicate across internal departments and with external academic and industry partners **Requirements** + PhD in Statistical Genetics, Genetic Epidemiology, or Computational Biology, Statistics, Computer Science or related fields with genetics focus + Several years of professional expertise + 5 years of post-PhD industry experience in disease translation within a pharmaceutical or biotechnology environment + In-depth biological and translational knowledge in one of the disease focus areas of Boehringer Ingelheim + Strong genetics expertise demonstrated through successful disease translation applications and a proven track record of delivering value through human genomics + Extensive computing and programming experience with demonstrated proficiency in relevant programming languages + Strong collaborator and presenter with proven experience in driving impact within matrix environments + Demonstrated project management expertise in leading cross-functional projects and teams **Eligibility Requirements:** + Must be legally authorized to work in the United States without restriction. + Must be willing to take a drug test and post-offer physical (if required) + Must be 18 years of age or older @computationalinnovation **Compensation Data** This position offers a base salary typically between $140,000 and $222,000. The position may be eligible for a role specific variable or performance-based bonus and or other compensation elements. For an overview of our benefits please click here. (***************************************************************** All qualified applicants will receive consideration for employment without regard to a person's actual or perceived race, including natural hairstyles, hair texture and protective hairstyles; color; creed; religion; national origin; age; ancestry; citizenship status, marital status; gender, gender identity or expression; sexual orientation, mental, physical or intellectual disability, veteran status; pregnancy, childbirth or related medical condition; genetic information (including the refusal to submit to genetic testing) or any other class or characteristic protected by applicable law.
    $140k-222k yearly 7d ago
  • R&D - Senior Researcher

    Duracell 4.8company rating

    Principal research scientist job in Bethel, CT

    This position is temporarily located in Bethel, CT, with relocation to the greater Atlanta Metro Atlanta at a later date. Expected is timing summer 2026. Relocation support will be provided and sent upon acceptance of the offer. One of the world's most iconic brands, Duracell, is the world's #1 battery and personal power company with over $2.4 billion in annual sales. In 2016, we joined Berkshire Hathaway, a U.S. multi-national conglomerate of holding companies. Berkshire is led by Warren E. Buffet, one of the world's most famous investors and business leaders. The company employs 365,000 people and ranks #3 in Fortune's 500 Most Admired Companies. The role will have technical responsibility for the coordination and execution of projects involving cell testing, cell characterization and technical support for the alkaline formulation team. Qualifications Education BS in Chemical Engineering, Chemistry, Physics or related technical field Skills Data Handling Able to collect, organize, and report data for PD team members Basic knowledge of statistical analysis of test data Can draw insights from data Cell testing Can pre-test inspections including dimensions, voltage, impedance Can use powered and hand tools to perform post-mortem tear down and failure analysis of tested cells Preparation of prototype cells for technical and consumer tests: Able to fabricate cell components such as electrodes, separators and current collectors Can assist with bench or pilot scale cell builds Can learn to set up and troubleshoot cell assembly equipment Communication: Intermediate level Microsoft Office skills Demonstrated capability to create clear, accurate, written reports Ability to present findings to audiences including senior leaders Problem solving, organizational skill Strong sense of ownership Responsibilities The senior researcher will: Assist a cell designer with formulation design for AA, AAA, C and D cells to support initiatives, cost savings, and quality improvement. Collect, analyze, and draw meaningful conclusions from large amounts of cell test data using statistical tools such as JMP. Design robust experimental plans using sound statistical methods. Partner with manufacturing engineering teams on project delivery requirements. Produce updates in the form of technical reports or presentations for project teams or for peer reviews Assist Product Design and Process Engineers with trials that run in manufacturing locations. Other duties as assigned.
    $88k-110k yearly est. Auto-Apply 60d+ ago
  • Scientist II

    Mindlance 4.6company rating

    Principal research scientist job in Ridgefield, CT

    · Operate and maintain flow cytometry instrumentation, including multi-laser cell sorters: · Perform instrument quality control procedures, and oversee instrument performance on a daily basis. · Perform preventive maintenance on cytometry instrumentation and equipment in the laboratory. · Troubleshoot instrument malfunctions and coordinate service repairs with field service engineers, as needed. · Perform cell sorting to support Research projects. · Provide technical support on instrument setup and use, experiment design, and data analysis to instrument Users. · Develop and maintain policies for Cytometry Core Facility. · Develop cytometry applications to support Research projects, as needed. Skills: · Previous experience working in a flow cytometry core facility preferred. · Has worked with Client cytometry instrumentation. Excellent communication, customer service, and interpersonal skills. · Mechanical and technical expertise. Experience developing and executing polychromatic flow cytometry panels. · Expertise in flow cytometry data analysis including, but not limited to FACS Diva software, and FlowJo. · Experience operating various cell sorters preferred. · Education: Bachelors Degree Additional Information All your information will be kept confidential according to EEO guidelines.
    $75k-107k yearly est. 3d ago
  • Scientist II

    Us Tech Solutions 4.4company rating

    Principal research scientist job in Ridgefield, CT

    US Tech Solutions is a global staff augmentation firm providing a wide-range of talent on-demand and total workforce solutions. To know more about US Tech Solutions, please visit our website ************************ We are constantly on the lookout for professionals to fulfill the staffing needs of our clients, sets the correct expectation and thus becomes an accelerator in the mutual growth of the individual and the organization as well. Keeping the same intent in mind, we would like you to consider the job opening with US Tech Solutions that fits your expertise and skillset. Job Description Title: Scientist II Location: Ridgefield Main Campus, 900 Ridgebury Road - R&D, Ridgefield, CT Duration: 2 year Duties: As a biomarker scientist, you will work with animal and human samples to identify, develop and validate novel biomarkers of kidney pathology and therapy. The biomarker assays will involve work with protein, RNA, and exosomes from tissue, urine, blood and require extensive knowledge, good lab skills and strong data analysis capability. Identify, develop, and validate novel biomarkers based on project needs. Develop and establish new biomarker assays. Perform general biomarkers assays and analyze the data. Clearly communicate timelines and study results within the group and with project teams. Skills: Requirements: Experience working in a lab to perform routine lab experiments (Cell culture, sample preparation, ELISA, Western blot, qRTPCR, etc.) Independently and /or collaboratively performs scientific experiments (in vitro, in vivo and ex vivo) with a predefined goal including developing new methodologies, protocols and/or testing procedures that contribute to project /research goals. Trouble-shooting skills during assay development and optimization Strong communication skills. Desired Experience, Skills and Abilities: Experience with biomarker assay technologies including antibody-based detection methods (e.g. ELISA) and multiplexed detection methods (e.g. Luminex, MSD) is desired. Hands-on experience in the development and validation of biomarker assays in the preclinical and clinical setting is desired. A proven track record of research accountability and productivity within a team setting is highly desired. The successful candidate will be a self-motivated, accountable bench scientist with the ability to apply his/her skills to meet diverse project needs in a fast-paced dynamic team environment. Qualifications Education: Bachelor's Degree in relevant scientific discipline (e.g. cell biology, molecular biology, biochemistry, etc.); Master's degree is highly preferred. Additional Information Thanks & Regards, Debasis Banerjee 201 - 613 - 5158 debasis@ustechsolutionsinc(dot)com
    $70k-108k yearly est. 3d ago
  • Scientist I (Chester, NY, US, 10918)

    Steris Corporation 4.5company rating

    Principal research scientist job in Chester, NY

    At STERIS, we help our Customers create a healthier and safer world by providing innovative healthcare and life science product and service solutions around the globe. Responsible for the activities related to validation of sterilization processes across STERIS operating facilities. Activities include calibration of data collection systems, such as maintaining dosimeters and dosimetry equipment, measurement of dosimeters for report generation; operation, and data collection related to portable temperature/humidity sensors; coordinating with external laboratories for equipment calibrations and maintenance; coordinating with Customers for test sample processing and requalification studies; coordination and proper handling of product samples for transfer to outside laboratories for testing; and other routine tasks as directed by the immediate supervisor or manager. What You'll Do as a Scientist I * Supports the conduct of scientific studies for investigation and validation purposes. * Contributes to creating and maintaining valid sterilization processes in the medical device or pharmaceutical industry that comply to FDA regulations, ISO, AAMI, and ASTM standards. * Acts as liaison between Customer and the facility leadership during Customer driven studies. * Assists in statistical analysis of data, such as variation analysis, specific to the modality in use. * Contributes to successful product processing by performing dosimeter calibrations or temperature/humidity sensor calibrations. * Ensures all internal equipment is calibrated per procedure requirements and coordinates calibrations with external vendors. * Ensures processes are maintained in a validated state by supporting periodic verifications and execution of revalidations or requalifications following changes. * Contributes to safe and accurate processing by notifying management of any event, item or documentation that may have a concern in regard to regulatory or specification compliance, Customer product quality, or employee safety. * Maintains a safe work environment by attending safety meetings with local facility, completing safety rounds, and tracking all hazardous materials as contained in the Safety Data Sheets. * Communicates in an effective manner by utilizing accepted business practices in a courteous and professional manner providing timely and accurate responses and service oriented offers of assistance. * Protects company confidential information by properly storing, retrieving and disseminating such information only to those authorized. * Exhibits a commitment to the AST shared values of Customer Satisfaction and Continuous Improvement through ensuring defect-free workmanship, assisting others to meet the Customer's needs, searching for efficient and effective ways to reduce waste, being active and accountable for Customer satisfaction, and satisfying the Customer's needs with a sense of urgency. * Contributes in a team effort by performing according to the guidelines outlined in the STERIS Code of Business Conduct, the GMP, Lean principles and other directives; supports the directives and decisions of higher level management and performs other duties as assigned. The Experience, Skills and Abilities Required Required Qualifications: * Bachelor's degree in a scientific discipline or related field. Preferred Qualifications: * Experience working in a regulated environment (e.g., GMP, GLP, or similar). * Strong organizational skills with the ability to manage multiple tasks and priorities effectively. * Demonstrated proactive approach to task management, ensuring timely completion of individual and team objectives. * Ability to take initiative and maintain accountability for assigned responsibilities. Pay range for this opportunity is $55,250 to $65,000, dependent on experience and skillset. This position is eligible for bonus participation. Minimum pay rates offered will comply with county/city minimums, if higher than range listed. Pay rates are based on a number of factors, including but not limited to local labor market costs, years of relevant experience, education, professional certifications, foreign language fluency, etc. STERIS offers a comprehensive and competitive benefits portfolio. Click here for a complete list of benefits: STERIS Benefits Open until position is filled. STERIS is an Equal Opportunity Employer. We are committed to equal employment opportunity to ensure that persons are recruited, hired, trained, transferred and promoted in all job groups regardless of race, color, religion, age, disability, national origin, citizenship status, military or veteran status, sex (including pregnancy, childbirth and related medical conditions), sexual orientation, gender identity, genetic information, and any other category protected by federal, state or local law. We are not only committed to this policy by our status as a federal government contractor, but also we are strongly bound by the principle of equal employment opportunity.
    $55.3k-65k yearly 36d ago
  • SR Scientist, Process Research Flow Technology

    Boehringer Ingelheim 4.6company rating

    Principal research scientist job in Ridgefield, CT

    Boehringer Ingelheim is currently seeking a talented and innovative Senior Scientist to join our Process Researc Flow Technology department located at our Ridgefield, CT facility. The Senior Scientist will design and execute independent research that supports R&D projects. The Senior Scientist is primarily responsible for performing and managing scientific and technical activities, which may also include responsibility for the management of scientific staff. As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development and delivery of our products to our patients and customers. Our global presence provides opportunity for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the companies´ success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, mobility, networking and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim´s high regard for our employees. **Duties & Responsibilities** + Independently propose, direct and perform scientific experiments with a predefined project goal including developing new methodologies, protocols and procedures; Keep abreast of relevant literature and maintain a high level of expertise in own field; Protect intellectual properties through new patent applications + Design, implement, and optimize continuous flow processes for complex chemical transformations. + Evaluate reactor configurations, mixing strategies, and heat/mass transfer considerations for scale-up + Apply Bayesian optimization and other machine learning techniques to streamline experimental design and process optimization. + Develop predictive models for reaction performance, yield, and impurity profiles + Collaborate with pilot plant and manufacturing teams to ensure seamless scale-up of flow processes + Develop an understanding of R&D team goals and work effectively toward achieving them in a multidisciplinary team environment; Either assumes departmental responsibility for projects when assigned or demonstrate leadership initiative in technical expertise areas to advance projects towards key milestones, as per requirement + Acquire knowledge of and assist in implementing new technologies; Ensure integration of new technologies and department initiatives into daily work to enhance productivity + Effectively communicate own and/or team´s work and deliver project updates to senior level management clearly in oral and written forms in the context of project goals + Responsible for lab/group operation including coaching, mentoring, training, supervising and developing staff when assigned; Participate in recruiting when needed + Develop and maintain visibility through presentations and publications; Take the lead in publications and patents when needed + Contribute to departmental administration when needed; Demonstrate fiscal responsibility with respect to cost of experiments, technologies, external collaborations, and travel + Comply with all regulations and policies; Perform all work in a safe manner; Maintain proper records (notebooks, batch sheets, etc.) per relevant SOPs. **Requirements** + Ph.D. Degree or equivalent (e.g. Master´s Degree with 10+ years of experience) in Organic Chemistry or Chemical Engineering + Demonstrated broad knowledge of organic chemistry and the ability to independently design and optimize organic reactions, and ability to evaluate and interpret data + Ability to communicate effectively both in verbal and written forms in inter-disciplinary environments + Must be able to work in a team environment, provide training and guidance to laboratory personnel **Compensation Data** This position offers a base salary typically between $140,000.00 and $222,000 USD. The position may be eligible for a role specific variable or performance based bonus and or other compensation elements. For an overview of our benefits please click here (***************************************************************** . All qualified applicants will receive consideration for employment without regard to a person's actual or perceived race, including natural hairstyles, hair texture and protective hairstyles; color; creed; religion; national origin; age; ancestry; citizenship status, marital status; gender, gender identity or expression; sexual orientation, mental, physical or intellectual disability, veteran status; pregnancy, childbirth or related medical condition; genetic information (including the refusal to submit to genetic testing) or any other class or characteristic protected by applicable law.
    $140k-222k yearly 16d ago
  • Scientist II

    Mindlance 4.6company rating

    Principal research scientist job in Ridgefield, CT

    Mindlance is a national recruiting company which partners with many of the leading employers across the country. Feel free to check us out at ************************* Job Description Studies the basic principles of plant and animal life and the effects of varying environmental and physical conditions such as radioactivity or pollution. Studies reactions of plants, animals, and marine species to parasites, bacteria, pharmaceuticals and chemicals. • Performing cell assay development and NTC studies on Client targets . • Skills: • Familiar with a variety of the fields concepts, practices, and procedures. • Education: • Bachelor's Degree • Cell biology and molecular biology skills a plus • Languages: • English Read Write Speak • Education: Bachelor's Degree • Skills: Familiar with a variety of the fields concepts, practices, and procedures.
    $75k-107k yearly est. 60d+ ago
  • Scientist IV

    Us Tech Solutions 4.4company rating

    Principal research scientist job in Ridgefield, CT

    US Tech Solutions is a global staff augmentation firm providing a wide-range of talent on-demand and total workforce solutions. To know more about US Tech Solutions, please visit our website ************************ We are constantly on the lookout for professionals to fulfill the staffing needs of our clients, sets the correct expectation and thus becomes an accelerator in the mutual growth of the individual and the organization as well. Keeping the same intent in mind, we would like you to consider the job opening with US Tech Solutions that fits your expertise and skillset. Job Description Duties: Perform dose formulation analysis under FDA GLPs for nonclinical studies. Provide dose formulation stability testing for GLP studies. Develop and validated analytical methods for doser formulation analysis. Assume responsibility for analytical support of nonclinical studies as contributing scientist/principal investigator working with BI nonclinical drug safety study directors and CRO scientists/study directors. Review laboratory notebooks and chromatographic data. Write analytical reports for inclusion in nonclinical study reports. Write dose formulation stability reports for GLP study support. Skills: Expertise in HPLC and analytical method development. Preferred experience in GLPs, Microsoft Office, Empower chromatographic data system. Qualifications Education: Bachelor's Degree and 7-10 years' experience in analytical chemistry/chromatography Additional Information Richha Saini Senior Clinical/Pharmaceutical Recruiter Tel: ************** Ext 7179 Direct: ************
    $70k-108k yearly est. 60d+ ago

Learn more about principal research scientist jobs

How much does a principal research scientist earn in Hyde Park, NY?

The average principal research scientist in Hyde Park, NY earns between $70,000 and $139,000 annually. This compares to the national average principal research scientist range of $87,000 to $184,000.

Average principal research scientist salary in Hyde Park, NY

$98,000
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