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Become A Principal Research Scientist

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Working As A Principal Research Scientist

  • Getting Information
  • Analyzing Data or Information
  • Identifying Objects, Actions, and Events
  • Updating and Using Relevant Knowledge
  • Documenting/Recording Information
  • Mostly Sitting

  • $96,410

    Average Salary

What Does A Principal Research Scientist Do At Abbvie

* We seek a highly motivated scientist, with a proven track record of accomplishment in the biopharmaceutical industry, to work in a multi-functional team environment
* The qualified candidate will deliver results in a team-oriented setting.
* The successful candidate will be responsible for setting project strategies, defining project responsibilities and timelines, providing leadership in a matrixed team setting and developing robust processes for cGMP manufacturing of AbbVie’s small molecule and/or antibody drug conjugate candidates.
* The successful candidate will conceive of and develop synthetic routes for early-stage clinical deliveries, demonstrate processes in the API Pilot Plant, develop commercial manufacturing processes, establish commercial control strategies, and transfer processes to commercial manufacturing sites.
* The position involves multi-disciplinary interactions with organic chemists, analytical chemists, engineers, solid state scientists, drug product development, and program management
* The selected candidate will collaborate with Asset Development Teams to advance clinical candidates
* It is expected that the candidate will utilize his/her expertise across CMC disciplines to further program goals via collaborations with drug product development, regulatory affairs, and commercial operations.
* The ideal candidate will have strong verbal and written communication skills, and will serve as the lead author on development reports and as a key contributor to regulatory submissions.
* Equal Opportunity Employer Minorities/Women/Veterans/Disabled
* Qualifications

What Does A Principal Research Scientist Do At Pfizer

* The individual is expected to manage a group of scientists within Analytical Development within Vaccine Research and Development, which has a focus on analytical assay development and analysis of various antigens (including viruses, proteins, and conjugates) used in vaccines under development.
* The expectation is that they will spend 30
* of their time on the bench.
* This individual is expected to independently design, execute and/or direct development, qualification and transfer of assays for testing/characterization of vaccine samples in support of process and formulation development.
* Primary methodologies include separation-based techniques, mass spectrometry, and NMR.
* Collaborate as necessary with appropriate colleagues and leaders within Vaccines and across other departments to understand the nature and approaches of the assays to be developed, qualified and transferred.
* Plan and coordinate support resources to ensure the timely execution of the analysis of vaccine samples to support the process and formulation development, as well as the release, stability and characterization testing of vaccine candidates for pre-clinical development.
* Supervise assigned staff including setting objectives and performance management, Ensure that the staff has received appropriate training and that the training is current.
* Provide work assignments to direct reports on a regular basis.
* Manage and assist reporting scientists in the prioritization of method development and analysis efforts.
* Identify appropriate scientific meetings/training workshops for direct reports.
* Write and review technical documents to support assay development, qualification, and transfer.
* Closely work with management to define long term strategies for the group.
* Represent the Analytical and Formulation Development group in relevant project team meetings within Vaccine Research and Development.
* Keep abreast of scientific/ technological developments by participating in scientific meetings/ seminars and through regular scientific review.
* Present experimental results at group meetings, project meetings and department meetings.
* Participate in scientific discussion with colleagues through internal journal clubs, as well as informal and formal scientific seminars and meetings.
* Manage daily, weekly and monthly laboratory activities, such as monitoring of equipment, completion and review of equipment logbooks, periodic laboratory cleaning and managing the laboratory waste, checking PMO status of lab equipment and resolving discrepancies.
* Manage storage of reagents and test solutions in accordance with departmental procedures.
* Satisfactorily complete all GLP and safety training in conformance with departmental requirements.
* Where applicable, performs job responsibilities in compliance with GLP and all other regulatory agency requirements

What Does A Principal Research Scientist Do At Lilly

* This role provides global strategic regulatory oversight and is assigned regulatory accountability on research and development projects for both vaccines and biopharmaceuticals.
* This is accomplished through expert knowledge and understanding of regulations, guidelines, regulatory precedence and the evolving regulatory framework to expedite the research/development and delivery of pure, safe, potent, and effective products for animals.
* To accomplish this purpose, it is necessary for the Principal Research Scientist to develop, maintain and extend relationships across Elanco functions/regions, regulatory agencies, partner companies, industry groups, and academia.
* Functions, Duties, Tasks:
* Provide leadership of the development and execution of regulatory strategies supporting licensure of new products and claim extensions.
* Anticipate and resolve key regulatory problems of global vaccine developments.
* Coordinate and/or conduct the preparation of new biological applications, submissions and responses to questions posed by regulatory agencies.
* Author and/or review of appropriate policies, SOPs, and guidance documents as needed.
* Maintain a positive business relationship with regulatory authorities.
* Align with global, regional and affiliate Regulatory staff to make sure local regulations are met.
* Work effectively and flexible within all related Elanco disciplines and external collaborators to achieve overall Elanco RA deliverables.
* Deliver scientifically sound high quality and approvable product submissions.
* Provide and accept challenge to deliver innovative scientific and regulatory solutions and create an innovative culture.
* Supervise/develop Elanco employees or Contractors and perform appropriate management activities as applicable.
* Manage project timeline and budget deliverables to facilitate delivery and maintenance of the Elanco pipeline
* Req ID:
* BR

What Does A Principal Research Scientist Do At Charles River Laboratories

* Function effectively as a study director in the direction and execution of assigned studies in compliance with GLP regulations as they apply to the conduct of nonclinical research.
* Participate in the proposal management and bid development process, serving as a key scientific contact for new business generated from established business relationships.
* Oversee specialty programs and serve as a key scientific contact for new business generated from established business relationships.
* Provide strategic advice for effective program management and project coordination.
* Design specialty preclinical programs in area of expertise.
* Independently interpret data for studies, provide scientific rigor, effectively integrate supporting data, and consistently prepare high-quality reports.
* Serve as project coordinator and function as a primary contact for key sponsors, coordinating proposal requests, site visits, and responses to client issues.
* Oversee sponsor interactions, including scientific program development, consulting on study and program design, scheduling, conduct, and reporting.
* Communicate and provide guidance for client issue resolution and interaction concerning regulatory issues.
* Provide oversight of the laboratory and mentor technical staff in areas such as protocol interpretation, method development and refinement, study-related problem resolution, and technique validation.
* Provide scientific expertise in study conduct, design, and interpretation.
* Review protocols, reports, and scientific documents of others as needed.
* Provide technical and scientific guidance to the research staff.
* Design and/or implement new experimental approaches to support studies and develop new business niches for Charles River Laboratories.
* Serve as a mentor to other scientists.
* Assist in training of new study directors.
* Function as departmental representative for interdepartmental communications and initiatives as required.
* Attend scientific meetings, conferences, and training courses to enhance job and professional skills.
* Present abstracts/posters at national meetings, when appropriate, to maintain a scientific presence and visibility in areas of individual expertise.
* Supervise research and/or scientific staff, as appropriate for scope of responsibilities.
* Direct activities of assigned group(s) to ensure effective performance of function.
* Interview and select qualified exempt-level departmental personnel.
* Recommend, review, and approve personnel actions, including hiring, promotions and raises.
* Partner with Human Resources in the handling of disciplinary issues.
* Prepare and/or approve appropriate personnel action paperwork.
* Ensure that management training and development needs are identified and programs initiated.
* Direct the development of departmental orientation and other training programs.
* Monitor performance of direct reports.
* Provide regular coaching and counseling.
* Prepare and deliver salary and performance reviews; review and approve performance and salary appraisals initiated by direct reports.
* Develop short and long-range operating objectives, organizational structure, and staffing requirements.
* Oversee the development of a departmental plan for backup and succession of key departmental personnel.
* Develop and recommend departmental budget.
* Authorize expenditures in accordance with budget.
* Approve budget and expenses of subordinates.
* Ensure optimum performance of group function.
* Recommend and implement techniques to improve productivity, increase efficiencies, cut costs, take advantage of opportunities, and maintain state-of-the-art practices.
* Direct the development and communication of departmental systems, SOPs, policies, and procedures.
* Partner with Human Resources to develop and approve departmental job descriptions; ensure communication of duties and responsibilities to employees.
* Perform all other related duties as assigned.
* Qualifications
* The following are minimum requirements related to theDirector of Genetic and In Vitro Toxicologyposition

What Does A Principal Research Scientist Do At Battelle Memorial Institute

* Contribute to long-term and short-term business development activities and client relationship activities as directed by senior staff within CHPS and TBL
* Be an effective task and project leader, responsible for coordinating, conducting, and overseeing research
* Perform assigned technical tasks and activities, in a timely manner as requested
* Prepare and present oral briefings to colleagues, and other professionals
* Improve performance in technical activities through job training and outside study
* This position reports to the Transportation Business Line Manager and is provided day-to-day work direction by senior human factors staff

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How To Become A Principal Research Scientist

Medical scientists typically have a Ph.D., usually in biology or a related life science. Some medical scientists get a medical degree instead of a Ph.D., but prefer doing research to practicing as a physician.


Students planning careers as medical scientists typically pursue a bachelor’s degree in biology, chemistry, or a related field. Undergraduate students benefit from taking a broad range of classes, including life sciences, physical sciences, and math. Students also typically take courses that develop communication and writing skills, because they must learn to write grants effectively and publish research findings.

After students have completed their undergraduate studies, they typically enter Ph.D. programs. Dual-degree programs are available that pair a Ph.D. with a range of specialized medical degrees. A few degree programs that are commonly paired with Ph.D. studies are Medical Doctor (M.D.), Doctor of Dental Surgery (D.D.S.), Doctor of Dental Medicine (D.M.D.), and Doctor of Osteopathic Medicine (D.O.). Whereas Ph.D. studies focus on research methods, such as project design and data interpretation, students in dual-degree programs learn both the clinical skills needed to be a physician and the research skills needed to be a scientist.

Graduate programs emphasize both laboratory work and original research. These programs offer prospective medical scientists the opportunity to develop their experiments and, sometimes, to supervise undergraduates. Ph.D. programs culminate in a thesis that the candidate presents before a committee of professors. Students may specialize in a particular field, such as gerontology, neurology, or cancer.

Those who go to medical school spend most of the first 2 years in labs and classrooms, taking courses such as anatomy, biochemistry, physiology, pharmacology, psychology, microbiology, pathology, medical ethics, and medical law. They also learn how to record medical histories, examine patients, and diagnose illnesses. They may be required to participate in residency programs, meeting the same requirements that physicians and surgeons have to fulfill.

Medical scientists often continue their education with postdoctoral work. Postdoctoral work provides additional and more independent lab experience, including experience in specific processes and techniques such as gene splicing, which is transferable to other research projects.

Licenses, Certifications, and Registrations

Medical scientists primarily conduct research and typically do not need licenses or certifications. However, those who administer drugs, gene therapy, or otherwise practice medicine on patients in clinical trials or a private practice need a license to practice as a physician.

Important Qualities

Communication skills. Communication is critical, because medical scientists must be able to explain their conclusions. In addition, medical scientists write grant proposals, because grants often are required to fund their research.

Critical-thinking skills. Medical scientists must use their expertise to determine the best method for solving a specific research question.

Data-analysis skills. Medical scientists use statistical techniques, so that they can properly quantify and analyze health research questions.

Decisionmaking skills. Medical scientists must determine what research questions to ask, how best to investigate the questions, and what data will best answer the questions.

Observation skills. Medical scientists conduct experiments that require precise observation of samples and other health data. Any mistake could lead to inconclusive or misleading results.

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Principal Research Scientist jobs

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Principal Research Scientist Demographics


  • Male

  • Female

  • Unknown



  • White

  • Asian

  • Hispanic or Latino

  • Unknown

  • Black or African American

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Languages Spoken

  • Chinese

  • German

  • French

  • Comanche

  • Portuguese

  • Ukrainian

  • Japanese

  • Carrier

  • Spanish

  • Russian

  • Polish

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Principal Research Scientist

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Real Principal Research Scientist Salaries

Job Title Company Location Start Date Salary
Principal Research Scientist Autel Robotics USA LLC San Ramon, CA Jan 12, 2016 $300,000 -
Principal Research Scientist Harvard University Boston, MA Apr 15, 2014 $210,000
Principal Research Scientist Harvard University Boston, MA May 05, 2014 $210,000
Principal Research Scientist The One-Page Company, Inc. San Francisco, CA Sep 01, 2016 $200,000
Principal Research Scientist The One-Page Company, Inc. San Francisco, CA Jan 09, 2016 $200,000
Principal Research Scientist EBAY Inc. San Jose, CA Oct 01, 2010 $170,000
Principal Research Scientist Synaptics, Inc. Santa Clara, CA Sep 17, 2012 $167,933
SR. Principal Research Scientist Autodesk, Inc. San Francisco, CA Jan 01, 2015 $164,403 -
SR. Principal Research Scientist Autodesk, Inc. San Francisco, CA Oct 01, 2012 $158,371 -
Principal Research Scientist Science Research Laboratory Inc. Somerville, MA Oct 03, 2009 $155,836
Principal Research Scientist Science Research Laboratory Inc. Somerville, MA Oct 03, 2012 $155,836
Principal Research Scientist Johnson & Johnson Pharmaceutical Research & Develo Radnor, PA Jan 28, 2011 $147,000
Senior Principal Research Scientist Cardionet, Inc. San Diego, CA Apr 21, 2010 $134,000
Principal Research Scientist Geron Corporation Menlo Park, CA Sep 06, 2012 $129,000
Principal Research Scientist Yahoo! Inc. Santa Clara, CA Jun 11, 2010 $127,900 -
Principal Research Scientist AOL Advertising, Inc. Palo Alto, CA Mar 28, 2016 $127,837
Principal Research Scientist (Acoustic Modeling) Nuance Communications, Inc. Burlington, MA Sep 18, 2016 $127,608 -
Principal Research Scientist Eli Lilly and Company Indianapolis, IN Jan 16, 2015 $127,517
Principal Research Scientist Eli Lilly and Company Indianapolis, IN Jan 16, 2012 $125,016
Principal Research Scientist Diamond Back Vision Reston, VA Jan 05, 2013 $120,698
Principal Research Scientist Battelle Memorial Institute Columbus, OH Jun 01, 2014 $100,008
Principal Research Scientist EMC Corporation Cambridge, MA Sep 22, 2011 $97,594 -
Principal Research Scientist Boston Scientific Corporation Saint Paul, MN Sep 03, 2015 $97,289
Principal Research Scientist Scientific Forming Technologies Corporation Columbus, OH Jan 28, 2014 $95,000 -
Principal Research Scientist TYCO Healthcare Group LP North Haven, CT Nov 30, 2009 $95,000
Principal Optical Research Scientist Dimensional Photonics International Inc. Wilmington, MA Jun 17, 2013 $95,000 -
Principal Research Scientist II Wyeth Chazy, NY Oct 01, 2009 $91,000 -

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Top Skills for A Principal Research Scientist


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Top Principal Research Scientist Skills

  1. Lab
  2. Analytical Methods
  3. Drug Discovery
You can check out examples of real life uses of top skills on resumes here:
  • Provided general clinical care of multiple laboratory animal species.
  • Led drug discovery and development programs in Inflammation area from Identification/Optimization of novel targets to deliver pre-clinical candidates.
  • Work in the Analytical Research & Development Department providing method development and validation supporting formulation for filing ANDA(s).
  • Developed respiratory safety pharmacology study design for commercial clients to meet ICH S7A Guidelines.
  • Develop new synthetic methods and improve existing ones to facilitate chemical synthesis.

Top Principal Research Scientist Employers

Principal Research Scientist Videos

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