Principal Research Scientist Jobs in Lower Makefield, PA

- 1,521 Jobs
  • Principal Scientist, Discovery & Preclinical Pharmacology

    The Principal Scientist shall be responsible for independently developing, maintaining and conveying key technical knowledge to move candidates through lead selection and IND. The Principal Scientist will lead basic research on rare disease biological mechanisms and optimize the pharmacological activity of drug candidates that intervene with the disease. Larimar Therapeutics Inc (Bala Cynwyd, PA) is a clinical-stage biotechnology company focused on developing treatments for complex rare diseases.
    $80k-114k yearly est.13h ago
  • Senior Clinical Scientist, Early Clinical Development - Hematology/Oncology & Cell Therapy

    Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. But working at Bristol Myers Squibb is anything but usual.
    $122k-147k yearly est.2d ago
  • Postdoctoral Researcher

    This Postdoctoral Researcher position is fully funded for three years and renewable after three years, and salary will be commensurate with NIH guidelines based on Postdoc years of experience. Discover why Cooper University Health Care is the employer of choice in South Jersey. At Cooper University Health Care, our commitment to providing extraordinary health care begins with our team. The Postdoctoral Researcher will study esophageal cancer and potentially lung cancer under the direction of Dr. Luke Chen, using cancer cells, mouse models and human tisues. The Surgical Research Laboratory, Department of Surgery, Cooper University Hospital and Cooper Medical School of Rowan University (CMSRU) is seeking to fill a Postdoctoral Researcher position to study targeted therapy of upper aerodigestive tract cancer.
    $53k-68k yearly est.18d ago
  • Y - Bioinformatics Scientist in Lawrenceville, NJ, US

    Summary: We are seeking a passionate scientist to join our Disease Strategy and Late Stage Hematology team in the Translational Bioinformatics group. 50%Onsite Senior Research Scientist, Disease Strategy and Late Stage Hematology, Translational Bioinformatics
    $78k-112k yearly est.8d ago
  • Scientist

    Title: Scientist - I (Assistant) Responsibilities: Bioanalytical Scientist responsibilities include, but are not limited to, the following:
    $53k-78k yearly est.10d ago
  • Scientist Formulation

    Scientist to join the team.
    $81k-123k yearly est.17d ago
  • Senior Clinical Scientist

    You can find out more about Kaitlyn & Meet at Meet is currently working with a start-up biotech company who are searching for a Sr. Clinical Scientist or AD. This position is being dealt with by Kaitlyn Sumner at Meet. The Senior Clinical Scientist will be responsible for designing and delivering clinical studies/programs through the pipeline.
    $110k-136k yearly est.4d ago
  • Scientist

    Location: Spring House, PA The Biologics Discovery department at Spring House is committed to discovering first-in-class biotherapeutics for some of the world's most challenging diseases.
    $65k-91k yearly est.4d ago
  • Associate Scientist

    Synbio Technologies is looking for an Associate Scientist to join the production team, which focuses on developing and commercializing gene synthesis and sequencing platforms. This Associate Scientist will collaborate with the Business Development, Project Management, and Marketing team to deliver research projects and launch new products. Synbio Technologies is committed to discovering and developing cutting-edge DNA technologies for the advancement of life science, synthetic biology, drug discovery and development, diagnostics and precision medicine and digital information DNA storages, etc. Synbio Technologies has built a comprehensive DNA reading (sequencing), DNA writing and DNA editing platforms enabling us to aid customers in one-stop DNA solutions.
    $67k-98k yearly est.21d ago
  • Scientist 2 - Research and Development (contract)

    Location: Raritan, NJ
    $79k-109k yearly est.8d ago
  • Associate Scientist, In Vivo

    This is a great opportunity for an In Vivo Associate Scientist to join and grow with an expanding Biotech company.
    $55k-81k yearly est.17d ago
  • Pharmaceutical Analytical Scientist/Manager/Director

    About Ascendia Pharmaceuticals: Ascendia is a specialty pharmaceutical Research and Development CDMO company dedicated to developing enhanced formulations of existing drug products, and enabling formulations for pre-clinical and clinical stage drug candidates. Ascendia specializes in creating formulations for poorly-water soluble molecules using nano-particle technologies. Ascendia assesses the feasibility of a broad array of formulation options in order to improve a drug's bioavailability and solubility. Ascendia's technologies include nano-emulsions, amorphous solid dispersions, nano-particles, injectable, and oral controlled release. Ascendia provides development and testing services - from discovery-stage molecules to life-cycle-management projects - creating formulation solutions with enhanced biopharmaceutical properties suitable for clinical scale-up. The mission of our company is to provide customized formulation solutions to “salvage” difficult compounds and to create advanced medicines to help patients “prevail” over their disease and enhance quality of life. About the Position: The qualified candidate will take an active role in supporting drug development by applying a variety of analytical methodologies to support physical and chemical characterization of drug substances (including raw materials and intermediates), biologics, and drug products. Working knowledge of analytical (e.g., HPLC-UV, HPLC-MS, GC-MS, spectroscopy) and physical chemical techniques (e.g., particle size, dissolution) used for the characterization of pharmaceutical substances and products is desired. Hand-on experience in HPLC method development and biological characterization is highly desired. Position level varies from bench chemist to principle scientist, depending on experience. Principal Responsibilities: The individual will be responsible for performing laboratory work in support of analytical testing of pharmaceutical projects, and relevant experience with the following analytical methodologies: chromatography, dissolution, KF, particle size will be desirable. Job responsibilities may include analytical method development and validation; stability and release testing; testing to support pharmaceutical development efforts; direct interaction with project team members, including presentation of data; critical review of data; preparation of technical reports; and evaluation of new instrumentation or analytical techniques. The candidate must be able to interact effectively with peers and leaders as part of a multi-disciplinary team and work in a fast-paced environment. Attention to detail, strong organizational skills, the ability to multitask, and effective interpersonal and communication skills are required. Qualifications The position requires a B.S, M.S. or Ph.D. in Pharmaceutical Chemistry, Analytical Chemistry, Biology, Bioengineering, Chemistry, or Pharmaceutical Sciences with relevant working experience in pharmaceutical industry. Working knowledge in analytical method development and validation under cGMP environment, esp biological characterization is highly desired. Experience with a wide-variety of software and information systems (e.g. Empower, ChemStation, or LIMS). Experience in problem-solving skills and instrument trouble-shooting. Good oral and written communication skills and the ability to write and review technical reports and scientific papers are desired. Working knowledge of pharmaceutical product development, CMC regulatory requirements, project management; and capability to collaborate with colleagues. EEO/AA M/F/V/D
    $79k-113k yearly est.18d ago
  • Research Associate

    In close consultation with a world-class Scientific Advisory Board that comprises a Nobel Laureate and a National Academy of Medicine member, SCRIPT is building an exciting pipeline of novel gene editing therapies based on our proprietary CasPlus platform, a novel gene editing approach that makes genome changes with greater precision, accuracy, and safety. Script provides a competitive compensation package inclusive of health benefits, and employees are eligible for a yearly performance-linked bonus as well as stock options. A Research Associate to support our therapeutic gene editing discovery efforts using the CasPlus platform, while also helping the team build and manage the laboratory. SCRIPT Biosciences is developing next generation CRISPR-based gene editing platforms to devise safe, efficient, and durable treatments for human disease. SCRIPT was co-founded by leading academic scientists from New York University (NYU), and is led by seasoned pharmaceutical industry leaders. In the heart of the New Jersey-Pennsylvania-Delaware Pharma corridor, our location in Philadelphia not only affords proximity to world-class academic and industrial research institutions, but also has one of the most vibrant artistic and culinary scenes to be found anywhere. The SCRIPT Research Laboratory is located at B-labs on Market Street in Philadelphia.
    $47k-76k yearly est.2d ago
  • Research Associate

    We seek a Research Associate I to join our dedicated group of scientists. What you will do at Integral Molecular: Integral Molecular is a Philadelphia-based biotech company specializing in the discovery and characterization of therapeutic antibodies.
    $47k-76k yearly est.22d ago
  • Sr. Validation Scientist

    The Senior Scientist position encompasses all areas of Technical Services with primary focus on technology transfer, scale-up, process optimization, process/packaging validation as well as routine commercial production support, equipment qualification and cleaning validation.
    $71k-99k yearly est.21d ago
  • Scientist/Senior/Principal Scientist, Proteomics

    We are seeking a highly motivated and experienced Senior Scientist with expertise in chemoproteomics/proteomics, mass spectrometry, and liquid chromatography. Key Responsibilities: Develop and optimize proteomic and chemoproteomic workflows, including sample preparation, LC-MS/MS analysis, data processing, and bioinformatics analysis. Design and execute experiments to investigate protein-protein interactions, post-translational modifications, and protein dynamics in a variety of biological contexts. Analyze and interpret complex data sets, generate hypotheses, and provide insights to guide research projects. Collaborate with interdisciplinary teams to integrate proteomics data with other omics data and functional assays to generate a comprehensive understanding of biological systems. Supervise and mentor junior scientists, provide technical guidance and leadership, and participate in the development of research strategies and grant proposals. Stay current with the latest scientific literature, technologies, and methodologies in proteomics and chemoproteomics. Qualifications: Ph.D. in Chemistry, Biochemistry, or a related field with a focus on proteomics or chemoproteomics. At least 5 years of hands-on experience in developing and applying proteomic/chemoproteomic techniques, including sample preparation, LC-MS/MS analysis, and data analysis. Strong expertise in mass spectrometry instrumentation, including Orbitrap, Q-TOF, and triple quadrupole platforms, and software packages for data analysis such as MaxQuant, Proteome Discoverer, and Skyline. Experience in liquid chromatography techniques, including nano-LC and HPLC. Strong track record of scientific publications and presentations. Excellent problem-solving skills, attention to detail, and ability to work independently and collaboratively in a team environment. Strong leadership skills, including the ability to supervise and mentor junior scientists. Excellent communication skills, including the ability to present complex data and concepts in a clear and concise manner. If you have a passion for innovation, a track record of scientific excellence, and a desire to work in a dynamic, collaborative environment, we encourage you to apply for this exciting opportunity as a Senior Scientist in chemoproteomics/proteomics. Please note that this position is an on-site role. If you are interested in this position, then please share your resume for immediate consideration!
    $95k-153k yearly est.23d ago
  • Senior Food Scientist (Hybrid)

    The Senior Food Scientist, Cookies & Crackers Senior Food Scientist, Cookies & Crackers
    $85.9k-158.9k yearly4d ago
  • Sr. Research Associate/Associate Scientist, Cell Engineering

    Century's genetically-engineered, universal iPSC-derived immune effector cell products are designed to specifically target hematologic and solid tumor cancers. Role: The Sr. Research Associate/Associate Scientist will utilize their experience and knowledge to design and execute research and development activities focused on engineered cell therapy technologies, with a focus on engineered immune cells. Century Therapeutics is developing novel allogeneic living cell products for oncology that overcome the limitations of current cell therapies. This platform differentiates Century from other approaches that utilize non-renewable donor-derived cells. Century's foundational technology is built on induced pluripotent stem cells (iPSCs) that have unlimited self-renewing capacity.
    $56k-85k yearly est.11d ago
  • Translational Bioinformatics Research Scientist

    Project Description: Our client is seeking a passionate scientist to join their Disease Strategy and Late-Stage Hematology team in the Translational Bioinformatics group.
    $89k-130k yearly est.8d ago
  • Staff Scientist

    Peak Environmental, A Nova Group, GBC Company
    $81k-122k yearly est.11d ago

Learn More About Principal Research Scientist Jobs

How much does a Principal Research Scientist earn in Lower Makefield, PA?

The average principal research scientist in Lower Makefield, PA earns between $79,000 and $159,000 annually. This compares to the national average principal research scientist range of $87,000 to $184,000.


What is the job market like for principal research scientists in Lower Makefield, PA?

You can compare the number of available jobs in Lower Makefield to the number of principal research scientist jobs in surrounding cities.

Active Principal Research Scientist Jobs In Nearby Cities

Nearby CityJobs In Nearby CityJobs in Lower MakefieldDifference
Abington, PA1,6520-1,652
Bensalem, PA1,9440-1,944
Bristol, PA1,8710-1,871
Cherry Hill, NJ1,3740-1,374
Ewing, NJ1,9260-1,926

What are the biggest employers of Principal Research Scientists in Lower Makefield, PA?

The biggest employers of Principal Research Scientists in Lower Makefield, PA are:
  1. Oracle
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