Principal research scientist jobs in Manchester, CT - 145 jobs

Reality Labs at Meta is seeking Research Scientists with experience in product-focused machine learning and signal processing research to advance our pioneering work in neuromotor interfaces, which has grown out of the acquisition of CTRL-labs. We're building a practical interface drawing on the rich neuromotor signals that can be measured non-invasively via surface electromyography (EMG) with single motor neuron resolution. This technology could become one of the main pillars for interaction with virtual and augmented worlds.We are a multi-disciplinary team of researchers investigating the nature of human neuromotor signals, developing novel signal processing and machine learning methods to infer a user's intent, and creating novel interaction techniques and user experiences. Help us unleash human potential by removing the bottlenecks between user intent and action. **Required Skills:** Research Scientist - CTRL Labs Responsibilities: 1. Research and develop Deep Learning or other computational models 2. Design methods, tools and infrastructure to analyze and leverage rich multimodal data sets 3. Set technical direction for a project of 2-3 researchers and engineers 4. Help transition and deliver our work from research into product 5. Adapt standard machine learning methods to best leverage modern parallel environments (e.g. distributed clusters, multicore SMP, and GPU) **Minimum Qualifications:** Minimum Qualifications: 6. Bachelor's degree in Computer Science, Computer Engineering, relevant technical field, or equivalent practical experience 7. Ph.D. degree in Computer Science and Engineering, Electrical Engineering, Statistics/Mathematics 8. Experience with developing machine learning models at scale from inception to business impact 9. Programming experience in Python and hands-on experience with frameworks such as PyTorch 10. Exposure to architectural patterns of large scale software applications 11. Must obtain work authorization in the country of employment at the time of hire, and maintain ongoing work authorization during employment **Preferred Qualifications:** Preferred Qualifications: 12. Proven track record of achieving significant results as demonstrated by grants, fellowships, patents, as well as first-authored publications at peer-reviewed AI conferences (e.g. NeurIPS, CVPR, ICML, ICLR, ICCV, ACL, and ICASSP) 13. Demonstrated software engineer experience via an internship, work experience, coding competitions, or widely used contributions in open source repositories (e.g. GitHub) 14. Experience bringing machine learning-based products from research to production **Public Compensation:** $184,000/year to $257,000/year + benefits **Industry:** Internet **Equal Opportunity:** Meta is proud to be an Equal Employment Opportunity and Affirmative Action employer. We do not discriminate based upon race, religion, color, national origin, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender, gender identity, gender expression, transgender status, sexual stereotypes, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics. We also consider qualified applicants with criminal histories, consistent with applicable federal, state and local law. Meta participates in the E-Verify program in certain locations, as required by law. Please note that Meta may leverage artificial intelligence and machine learning technologies in connection with applications for employment. Meta is committed to providing reasonable accommodations for candidates with disabilities in our recruiting process. If you need any assistance or accommodations due to a disability, please let us know at accommodations-ext@meta.com.

Associate Principal Scientist, Process Chemistry FLSA Status: Exempt Salary: $130,000-$160,000 Pharmaron is thrilled to invite you to join us as our newest Associate Principal Scientist at our Coventry, RI facility! If you're craving a role that offers challenges, growth, and meaningful impact, then this is the opportunity you've been waiting for. Job Overview: The Associate Principal Scientist is a subject matter expert within Process Chemistry and is responsible for solving highly complex chemical development problems for ground-breaking Active Pharmaceutical Ingredient (API) development projects: Responsibilities: Design and execute core experiments, interpret results, and plan additional experiments in a timely manner to solve assigned problems of high complexity. Demonstrate expertise in the core chemistry laboratory skills required to support development and / or scale up of chemical processes Actively participate in the development of new technologies or methodologies Effectively communicate, coordinate and collaborate with cross-functional project groups to ensure that scientific work is appropriately documented such that the broader collaborative inputs and efforts are combined to maximum effect in the production of reports, manuscripts, and presentations. Document and report results of all experiments in a manner consistent with department practices and governing policies, as applicable, which may include significant contributions to manufacture of API for GLP toxicology studies or for GMP manufacture of clinical supplies. Contribute to effective team planning and mentor less experienced staff on core functional technical and procedural matters as opportunities arise. Follow all key internal business practices and external regulations governing the role (e.g. GLP or GMP), and adhere to all corporate policies governing the business activities. What We're Looking For: PhD in Chemistry or related field. Multi-year industrial experience within relevant role Evidence of experience in successful application of analytical / physical skill sets to resolve high complexity chemical problems Evidence of ability to effectively contribute to multi-disciplinary scientific teams Competency in the routine use of core instrumentation and laboratory techniques and higher end instrumentation and laboratory techniques. Effective written and oral communication skills, including the ability to effectively present scientific findings to colleagues Ability to work cross-functionally and manage projects effectively Excellent organizational, planning and time management skills Why Pharmaron? Pharmaron is a premier service provider for the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities and established a broad spectrum of research, development, and manufacturing service capabilities throughout the entire drug discovery, preclinical, and clinical development process across multiple therapeutic modalities, including small molecules, biologics, and CGT products. With over 21,000 employees and operations in the U.S., the U.K. and China. Pharmaron has an excellent track record in delivering R&D solutions to its partners in North America, Europe, Japan, and China. Collaborative Culture: You will thrive in our inclusive and collaborative environment, where teamwork and innovation go hand in hand. Here, your voice matters, and your contributions make a real impact. "Employees Number One" and "Clients Centered" are the core cultural values at Pharmaron. Our culture, which sets Pharmaron apart from other organizations, has evolved from our deep commitment to our employees, partners, and collaborators. Benefits: As part of our commitment to your well-being, we offer a comprehensive benefits package: Insurance including Medical, Dental & Vision with significant employer contributions Employer-funded Health Reimbursement Account Healthcare & Dependent Care Flexible Spending Accounts 100% Employer-paid Employee Life and AD&D Insurance, Short and Long Term Disability Insurance 401k plan with generous employer match Access to an Employee Assistance Program How to Apply: Ready to seize this incredible opportunity? Join us at Pharmaron and be part of a dynamic team driving innovation and excellence in biopharmaceutical research and development. Apply online today! As an Equal Employment Opportunity and Affirmative Action employer, Pharmaron values diversity and inclusion in the workplace, fostering an environment where all individuals are empowered to succeed. Join us in our mission to make a difference in the world of life sciences.

Clinical Research Investigator DM Clinical Research, the largest privately-owned research management organization in the Houston area and one of the top 50 in the country, is looking for an Investigator for our sites in Hartford, CT. This individual will conduct all clinical trials (studies) according to ICH, GCP, local regulations, study protocols, and company processes. Responsibilities Ensures the medical well-being and safety of the participants through the safe performance and execution of the studies. Assists in maintaining clinical oversight and quality on the studies registered on and delivers on study targets, thereby contributing to the commercial success of the site. Reviews enrollment progress, pre-screening and screening success rates, screen failure rates, safety, and retention of participants. Interprets protocols and IB and participates in initiatives to strategize for patient recruitment. Carries out clinical evaluation and assessment of participants to ensure eligible participants are enrolled onto studies. Ensures and protects the welfare and safety of participants through ethical conduct. Fulfills and comply with all medical duties as per protocol, SOP/COP and ICH GCP and local regulations. Exercises meticulous attention to detail in documentation and patient care. Requirements Medical License (MD, DO) At least 2 years of experience as a Clinical Research Investigator. Spanish Bilingual a plus.

Mindlance is a national recruiting company which partners with many of the leading employers across the country. Feel free to check us out at ************************* Job Description Position Description: The successful candidate will provide quantitative bioanalytical support using LC-MS/MS for a variety of high throughput in vitro ADME profiling assays. In this hands-on role, the candidate will perform sample analyses by mass spectrometry, and will review, interpret and report results. Instruments and software from various vendors including Sciex (Analyst) and Thermo (Excalibur) will be used along with custom internal data processing software to acquire data and process results. The successful candidate will also troubleshoot HPLC and MS instrumentation as necessary. Position Requirements: BS or MS in chemistry, with specialization in analytical chemistry preferred, along with 1 to 5 years of relevant pharmaceutical experience is required. Training or experience in mass spectrometry and separation science, as well as hands-on experience in quantitative LC-MS/MS analysis are desired. Proficiency in general computer software, including vendor specific instrument control and analysis tools, is required. Strong interpersonal and communication skills, both oral and written, are required as is commitment to working as a team player within a multifunctional organization. A working knowledge of allied disciplines such as computer science, lab automation, drug metabolism, pharmacokinetics and synthetic chemistry is helpful. Qualifications The successful candidate will also troubleshoot HPLC and MS instrumentation as necessary. LC-MS/MS analysis BS or MS in chemistry Additional Information Thanks & Regards Riya ************

Established in 1991, Collabera has been a leader in IT staffing for over 22 years and is one of the largest diversity IT staffing firms in the industry. As a half a billion dollar IT company, with more than 9,000 professionals across 30+ offices, Collabera offers comprehensive, cost-effective IT staffing & IT Services. We provide services to Fortune 500 and mid-size companies to meet their talent needs with high quality IT resources through Staff Augmentation, Global Talent Management, Value Added Services through CLASS (Competency Leveraged Advanced Staffing & Solutions) Permanent Placement Services and Vendor Management Programs. Collabera recognizes true potential of human capital and provides people the right opportunities for growth and professional excellence. Job Description •Assist Lead Biomarker Scientist to develop, optimize, validate, and perform FACS-based and other biomarker assays to support studies in New Haven CRU and external protocols if needed. •Performed general flow cytometry operation, including sample preparation and analysis. Experience in FACSCanto Flow Cytometer and FACSDiva software. •Performed quality control checks on Flow Cytometers and other Laboratory instruments, reagents, and techniques. •Operated, maintained, calibrated and trouble shoot Flow cytometers and other Laboratory instruments according to SOPs. •Maintained quality control and calibration logs of all Flow Cytometers. •Analyzed, summarized and document experimental results. •Performed data entry using laboratory information management system (LIMS) •Write experimental SOPs. •Update Biomarker Lead on the status, results and problems in method development and performance of the assays. •Complete all NHCRU/Pfizer required training. •Have a working knowledge of Microsoft office including Excel, Word and PowerPoint. •Possess multi-tasking and organizational skills. •Experience in ELISpot Assays and FlowJo software a plus. Qualifications MS in Biology/BioChemistry/Medical Technology plus 1 year of relevant experience BS in Biology/BioChemistry/Medical Technology or 3 years of relevant experience. Additional Information To schedule interview or get any further information feel free to contact: Sagar Rathore ************ ******************************

Under the direction of Dr. Tsampikos Kottos, the Research Scientist will be working on the research effort on “AI-Guided Self-Organization: Tailoring Disorder to Shape Complex Nonlinear Dynamics”. The project aims to combine modern machine learning with physical insight and high-throughput automated experiments to enable unprecedented AI-assisted design and control of complex self-organization. Guided by studies with universal physical models, the effort will develop new techniques for physics-guided inverse design and control. The theoretical activity will be complemented with experimental proof-of-principle concepts using networks of electronic oscillators. These will function as a training and testing ground to enable universal techniques for AI-based design and control of complex systems. Responsibilities include: Supervise graduate and undergraduate students Manuscript preparation and editing and conference presentations. Assisting in grant preparation and grant applications Other duties as assigned This is an on-campus position and the position is approved for two years with the potential to extend another year. Information about the WTICS group can be found at ************************************ Minimum Qualifications PhD in Physics, Applied Mathematics, Electrical or Mechanical Engineering or related field. Knowledge of theory of metamaterials. Knowledge of coupled mode theory. Knowledge of nonlinear dynamics. Knowledge of machine learning. Preferred Qualifications Experience in developing proof-of-principle RF and microwave experimental platforms that allow validation of the theoretical concepts. Demonstrated commitment to work within a diverse environment and interact openly with individuals of different backgrounds. Position is open until filled. As part of your application, please upload a cover letter and resume. Compensation: $61,300.00 - $66,800.00Work Location: On Campus All offers to external applicants are contingent on the candidate's completion of a pre-employment background check screening to the satisfaction of Wesleyan University. Wesleyan University, located in Middletown, Connecticut, does not discriminate on the basis of race, color, religious creed, age, gender, gender identity or expression, national origin, marital status, ancestry, present or past history of mental disorder, learning disability or physical disability, political belief, veteran status, sexual orientation, genetic information or non-position-related criminal record. We welcome applications from women and historically underrepresented minority groups. Inquiries regarding Title IX, Section 504 or any other non-discrimination policies should be directed to Vice President for Equity and Inclusion, Title IX and ADA/504 Coordinator. Wesleyan University complies with the Clery Act and maintains records of campus crime statistics and security policies. Copies of Wesleyan University's Clery Act Report are available on request and online at ************************************************* Experience is taken into consideration in the determination of salary offers. For more information visit ********************************************************************** Wesleyan offers a broad range of employee benefits and development opportunities, including comprehensive group insurance plans, wellness programs and incentives, generous paid time off and retirement plans, flexible work schedules, employee and dependent tuition programs for those who qualify. Detailed information on the benefits of working at Wesleyan is located at: ***********************************************************

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins laboratories work with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate. The Eurofins network of companies is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organisation services. It is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organisations. It also has a rapidly developing presence in highly specialised and molecular clinical diagnostic testing and in-vitro diagnostic products. In over 30 years, Eurofins has grown from one laboratory in Nantes, France to 58,000 staff across a decentralised and entrepreneurial network of 900 laboratories in over 54 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products. In 2021, Eurofins generated total revenues of EUR 6.72 billion, and has been among the best performing stocks in Europe over the past 20 years. Job Description Analysis of powder samples for key physical properties (such as particle size distribution, bulk density, true density, powder flow, particle shape) Analysis of liquid samples for key physical properties (such as viscosity and surface tension) Using techniques such as optical microscopy, laser diffraction particle size analysis, electron microscopy, shear cell testing, compaction simulation, etc. Qualifications Bachelor's degree in chemistry or other science related degree concentration, or equivalent directly-related experience At least one year experience in particle and powder characterization Strong computer, scientific, and organizational skills Proficient in learning new techniques, developing and carrying out experimental plans, and performing multiple tasks simultaneously Experience in data handling and scientific/engineering computations Excellent communication (oral and written) and attention to detail Ability to work independently and as part of a team, self-motivation, adaptability, and a positive attitude Ability to keep accurate records, follow instructions, and comply with company policies At least one year experience in particle and powder characterization Additional Information Position is full-time, Monday - Friday 8am to 5 pm Ability to work overtime as required. Tasks require repetitive motion and standing for long periods of time. May be required to respond to off-shift operational issues. Candidates currently living within a commutable distance of Groton, CT are encouraged to apply. Excellent full-time benefits, including comprehensive medical coverage, dental, and vision options Life and disability insurance 401(k) with company match Paid vacation and holidays #LI-EB1 Authorization to work in the United States indefinitely without restriction or sponsorship Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.

Makro Scientific: Growing Pharmaceutical, Biotechnology and Medical Device companies always need TOP Talent. Since 1996, MakroScientific's proven staffing solutions have helped many Life Sciences companies succeed and visualize their goals by increasing innovation and decreasing costs while maintaining the complex service level expectations. Our global presence with offices in USA (NJ, PA, IL, CA) and offices in UK, Europe and Asia enables us to be a powerful contributor and connector of right Talent. Job Description The scientist will work closely with his/her supervisor to conduct routine in vitro drug metabolism studies designed to evaluate molecules as inhibitors of drug metabolizing enzyme. The individual will work in the Pharmacokinetics, Dynamics and Metabolism (PDM) department to support R&D portfolios.Perform standard chemical calculations to accurately prepare laboratory solutions and dilutions for screening.Conduct in vitro experiments with bio hazardous material both manually and with robotic systems. Quantification of samples by LC/MS and analyzing data using excel and/or Graph Pad Prism.Generate high quality data in a timely manner, reviewing and uploading data into databases.With support of his/her supervisor and colleagues, the candidate will work as a member of a team and be accountable for the critical appraisal of their results.Accurate record keeping and ability to follow precise steps in a protocol are required.Perform and maintain lab supply inventory and order as appropriate Qualifications BS in chemistry, biochemistry, biology or related field.Exp 3-6 years Additional Information Must possess effective verbal and written communication skills.Ability to perform and record data entry via computer systems while adhering to laboratory SOPs is mandatory.Previous knowledge of Universal Precautions, Blood Borne Pathogen training, Microsoft Office including Excel and Graph Pad Prism is preferable.Candidate must be able to quickly learn new in-house software for data management.The candidate will have solid training and knowledge in standard chemical calculations to accurately prepare laboratory solutions and calculate dilutions for screening, Experience in assay development and mechanisms of enzyme inhibition are preferred.Experience with automation of assays and LC-MS is also desired.

Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost. Job Description Good knowledge of Ligand binding assays as platforms for resolving pharmacokinetic parameters and a strong understanding of method development processes, acceptance criteria and incurred sample reanalysis for regulated studies/compounds. Good knowledge of regulatory requirement governing drug safety evaluation. Good understanding of modern bioanalytical chemistry. Demonstrated excellent communication, organization and interpersonal skills. Must have BS/BA degree in biology or chemistry and a minimum of 3 years of bioanalytical experience. Experiences in LBAs is highly desirable. Working knowledge of regulatory requirements (i.e., GLPs) is also required. Proven track record in working in the ADME related roles is preferred. Qualifications Must have BS/BA degree in biology or chemistry and a minimum of 3 years of bioanalytical experience. Experiences in LBAs is highly desirable. Working knowledge of regulatory requirements (i.e., GLPs) is also required. Proven track record in working in the ADME related roles is preferred. Additional Information For more information, please contact Sneha Shrivastava ************

The Associate Scientist will serve as the platform lead for Xenium spatial transcriptomics projects at Single Cell Biology Lab (SCBL) within The Jackson Laboratory for Genomic Medicine, ensuring the timely delivery of high-quality, robust data. The SCBL is a core facility supporting the scientific research community with cutting-edge single-cell technologies, including dissociative single-cell omics, spatial omics, and high-content screening. This role is central to the lab's spatial genomics capabilities, requiring deep expertise in the Xenium workflow, exceptional project coordination, and strong communication with scientific stakeholders. The ideal candidate will be the technical expert for all Xenium operations from sample handling and experimental execution to data quality control and workflow optimization. You will leverage your strong background in molecular biology, tissue handling, and single-cell technologies to enhance and expand the capabilities of the Single Cell Biology Lab. Key Responsibilities & Essential Functions * Platform Leadership: Serve as the Xenium Platform Lead and Subject Matter Expert (SME), providing guidance and support to end-users and the broader scientific community. * Project Management & Execution: Coordinate the full lifecycle of Xenium projects, including managing sample submission and receiving, providing service quotations, executing experiments, and ensuring final data quality control (QC). * System Maintenance: Oversee instrument management, including maintaining the Xenium instrument, managing stock and inventory, and performing advanced troubleshooting of equipment and assays. * Process Optimization & Development: Drive the continuous improvement of the platform by optimizing existing workflows and developing new spatial genomics capabilities and technologies. * Scientific Awareness: Stay current with the newest developments in the spatial genomics field and effectively communicate technological updates to the team and research community. * Meticulous Documentation: Maintain excellent documentation standards, including comprehensive lab notebooks, SOPs, error/work logs, metadata, and sample information. * Stakeholder Communication: Ensure seamless communication with end-users, vendors, colleagues, and managers to coordinate and successfully complete all Xenium projects. Knowledge, Skills, and Abilities Required * Education: Master's degree (M.S.) in Biology, Molecular Biology, or a related scientific field. * Experience: 2-4 years of experience in a core facility or industry setting. * Molecular & RNA Biology: Deep and comprehensive understanding of RNA and molecular biology principles, including associated assays. * Imaging-Based Spatial Genomics Expertise: Hands-on experience with FISH-based platforms, including 10x Genomics Xenium, MERFISH, and seq FISH. * Technical Breadth: Comprehensive knowledge of various spatial genomics technologies (e.g., Xenium, Visium, MERFISH, seq FISH). * Sample Handling: Direct experience with tissue sectioning, handling, and immunohistochemistry (IHC) techniques. * Documentation: Experience in writing Standard Operating Procedures (SOPs) and familiarity with Laboratory Information Management Systems (LIMS) and Electronic Lab Notebooks (ELN). * Operational Skills: Proven project and lab management experience, including managing stock, inventory, and instrument uptime. * Soft Skills: Exceptional communication, interpersonal, and presentation skills; proven ability to thrive as a team player within interdisciplinary groups. Preferred * Education: Ph.D. preferred * Single-Cell Experience: Hands-on experience with single-cell technologies (e.g., 10x Chromium, smart-seq, split-and-pool methods). * Biopharma Industry Experience: Preferred experience working in an industrial setting, such as the biotechnology or pharmaceutical sector, demonstrating familiarity with industry-standard workflows and requirements. * Histology Expertise: Experience in histopathology. * Development: Proven track record in technology development or assay optimization. Pay Range: $69,711 - $90,624 #CA-NL6 About JAX: The Jackson Laboratory is an independent, nonprofit biomedical research institution with a National Cancer Institute-designated Cancer Center and nearly 3,000 employees in locations across the United States (Maine, Connecticut, California), Japan and China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health. Founded in 1929, JAX applies over nine decades of expertise in genetics to increase understanding of human disease, advancing treatments and cures for cancer, neurological and immune disorders, diabetes, aging and heart disease. It models and interprets genomic complexity, integrates basic research with clinical application, educates current and future scientists, and provides critical data, tools and services to the global biomedical community. For more information, please visit ************ EEO Statement: The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.

About Us Cloverleaf Bio is an early-stage therapeutics company that is developing a new class of engineered tRNA therapeutics. Our tRNAs target an underappreciated vulnerability of cancer: addiction to high levels of tRNA modifying enzymes. Cloverleaf's approach to drugging tRNA modifying enzymes uses engineered “trojan horse” tRNAs to modulate translation in cancerous cells. The programmability, potency, and specificity of our tRNAs gives us the potential to dramatically improve cancer treatment. The Job We are seeking an experienced RNA Biochemist to join our team. In this position, you will work in close conjunction with our founding team in the creation and development of a completely novel family of RNA therapeutics. Your responsibilities will range from designing and performing both low and high-throughput RNA screening assays, generation of RNA sequencing libraries, performing mechanistic studies in cells on lead candidate RNAs, and diving into new disease areas beyond oncology. About You Excited by the science. We are excited by how science can improve the world and are looking for people who are too. Flexible. We wear many different hats and are looking for people who are willing to do whatever it takes to pitch in and get the job done. Resilient. Working in an early-stage startup can be hard. Science is hard. We are looking for people who have a demonstrated track record of sticking with complex problems for the long haul. Cooperative. As a small team, communication and collaboration are key. We are looking for people who thrive working both independently and collaboratively. Qualifications: PhD in Biochemistry, Molecular Biology, Genetics or related fields. Strong problem solving skills. Demonstrated ability to independently drive research projects to completion in academic or industrial settings. Experience with standard molecular biology techniques, including but not limited to, RNA/DNA extraction, PCR, RT-PCR, qPCR, western blotting, etc. Skilled in mammalian cell culture, passaging/seeding cells, etc. Nice to haves: Competency generating libraries for RNA sequencing (such as mRNA-seq, CLIP-seq, etc.). Comfortable at analyzing NGS data analysis using conventional bioinformatics tools. Research experience in tRNA, RNA biology and/or RNA modifications field. Experience with design/development RNA therapeutics and lipid nanoparticles. Experience with mouse models of oncology. Benefits Competitive salary commensurate with experience and strong equity incentives. Medical, dental, and vision coverage. Brand new lab space in BioLabs New Haven in downtown New Haven, close to the Yale Shuttle, I-95/91 and Metro North. We will provide a stimulating, collegial, and fast-paced environment. If you are interested in joining our team, then we are excited to hear from you! Please submit resumes at cloverleafbio.com

Global Channel Management is a technology company that specializes in various types of recruiting and staff augmentation. Our account managers and recruiters have over a decade of experience in various verticals. GCM understands the challenges companies face when it comes to the skills and experience needed to fill the void of the day to day function. Organizations need to reduce training and labor costs but at same requiring the best "talent " for the job. Qualifications BSc required with 2 years wet lab chemistry experience preferred. Degree in Chemistry, Biochemistry, Molecular Biology. • Preferred coursework includes Organic Chemistry, Statistics, Analytical Chemistry, Physical Chemistry, Biological Chemistry, corresponding Lab courses. TECHNICAL SKILLS • Design of Experiments • Kinetic analysis • Method development • Method troubleshooting • Some NMR experience preferred • pH measurement • weighing • pipetting POSITION RESPONSIBILITIES • Carry out chemical modifications of biopolymers under supervision. Involves weighing, pipetting, and mixing reagents under controlled conditions. • Sample purification using dialysis and filtration. • Preparation of samples for NMR analysis • Documention in electronic lab book • NMR analysis under supervision. Involves straightforward data collection. • Processing of NMR data • Statistical analysis of data • Preparation of aqueous buffers with pH analysis • Other routine duties and responsibilities involved in lab work. Additional Information $39//hr 12 months

Job Title: Senior Scientist / Associate Principal Scientist, Chemical Engineering R&D FLSA Status: Exempt Salary: $100,000-$160,0000 Pharmaron is a global CRO helping pharma and biotech companies bring new therapies to life. With over 21,000 employees worldwide across 23 locations in the US, UK and China, we support drug discovery through to manufacturing with fully integrated, high-quality services. We're proud of the impact we make and just last year, we supported over 780 discovery projects, 1,000+ CMC programmes, and 1,000+ clinical trials across all phases. Our teams are involved in everything from small molecules to biologics and gene therapies, and we work with more than 3,000 global customers. To learn more, visit ****************** About the Role The Pharmaron Process Chemistry department is seeking highly motivated Chemical Engineers for an exciting role involving hands-on small-molecule process development and scale-up from laboratory to commercial manufacturing. Engineers in this position will design, plan, and implement both chemistry laboratory and in-silico experiments to support process and technology development for active pharmaceutical ingredients (APIs). This position will combine elements of chemistry, engineering, technology development, and data analysis to optimize manufacturing processes. Strong teamwork, innovation, creativity, and organizational skills are essential, along with clear and confident communication to address technical challenges. Effective collaboration across multidisciplinary teams in the US, UK, and China, is critical, and a strong commitment to safety, quality compliance, and technical leadership is expected throughout all activities. Key Responsibilities Perform hands-on small molecule process development and scale-up work. Use Design of Experiments (DoE) for process screening, optimization, and robustness studies. Define CPPs, PARs, NORs, and contribute to the development of scalable control strategies. Apply process analytical technology (PAT) and process modeling. Evaluate and model kinetics, mixing, mass/heat transfer, and reactor performance. Conduct independent research to achieve mechanistic understanding for rational process design. Design and optimize key unit operations including crystallization, filtration, drying, distillation, and extraction. Use process modeling tools to inform scale-up strategies. Translate lab-scale findings into actionable parameters for kilo lab and GMP manufacturing. Drive cycle time reduction and process intensification initiatives. Implement innovative technologies such as continuous flow chemistry and automation platforms. Support internal and external tech transfer activities, including scale-up studies, modeling, and verification experiments. Support development of complex transformations such as catalytic hydrogenation. Exhibit a mindset of safety and quality compliance. Collaborate cross-functionally within US, UK, and China-based teams. Required Experience & Skills Education Minimum Requirement: The position requires either a BS and/or MS in Chemical Engineering (or comparable) from an accredited college/university plus at least 5 years of relevant work experience in small-molecule chemical process development - OR - a PhD in Chemical Engineering (or comparable) from an accredited college/university with at least 2 years of relevant work experience post PhD defense. Experience performing lab-based research/process development in a chemical engineering-related area. Experience with organic chemical synthesis and wet chemistry. Experience with small molecule pharmaceutical drug substance development. Experience applying statistical experimental design (i.e. Design of Experiments) and/or process modeling. A high level of innovation, creativity, and self-initiative. Highly effective communication and collaboration skills. Good organizational, interpersonal, writing, and time management skills. Preferred Experience & Skills Experience with process scale-up and/or technology transfer, moving from laboratory to pilot plant or production scale. Familiarity with concepts and application of cGMP and GDP during pharmaceutical development and production. Demonstrated experience with chemical engineering-related technology development. Familiarity with kilo-scale laboratory equipment. Experience with process modeling (e.g., population balance modeling, distillation modeling). Knowledge with milling equipment (spiral jet mills, pin mills, co-mills, rotor-stator wet mills). Why Pharmaron? Collaborative Culture: Thrive in our inclusive and collaborative environment, where teamwork and innovation go hand in hand. Here, your voice matters, and your contributions make a real impact. "Employees Number One" and "Clients Centered" are the core cultural values at Pharmaron. Our culture, which sets Pharmaron apart from other organizations, has evolved from our deep commitment to our employees, partners and collaborators. Benefits: As part of our commitment to your well-being, we offer a comprehensive benefits package: Insurance including Medical, Dental & Vision with significant employer contributions Employer-funded Health Reimbursement Account Healthcare & Dependent Care Flexible Spending Accounts 100% Employer-paid Employee Life and AD&D Insurance, Short and Long Term Disability Insurance 401k plan with generous employer match Access to an Employee Assistance Program How to Apply: Ready to seize this incredible opportunity? Join us at Pharmaron and be part of a dynamic team driving innovation and excellence in biopharmaceutical research and development. Apply online today! Pharmaron is a premier service provider for the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities and established a broad spectrum of research, development, and manufacturing service capabilities throughout the entire drug discovery, preclinical, and clinical development process across multiple therapeutic modalities, including small molecules, biologics, and CGT products. With over 21,000 employees and operations in the U.S., the U.K. and China. Pharmaron has an excellent track record in delivering R&D solutions to its partners in North America, Europe, Japan, and China. As an Equal Employment Opportunity and Affirmative Action employer, Pharmaron values diversity and inclusion in the workplace, fostering an environment where all individuals are empowered to succeed. Join us in our mission to make a difference in the world of life sciences.

Position Description: The successful candidate will provide quantitative bioanalytical support using LC-MS/MS for a variety of high throughput in vitro ADME profiling assays. In this hands-on role, the candidate will perform sample analyses by mass spectrometry, and will review, interpret and report results. Instruments and software from various vendors including Sciex (Analyst) and Thermo (Excalibur) will be used along with custom internal data processing software to acquire data and process results. The successful candidate will also troubleshoot HPLC and MS instrumentation as necessary. Position Requirements: BS or MS in chemistry, with specialization in analytical chemistry preferred, along with 1 to 5 years of relevant pharmaceutical experience is required. Training or experience in mass spectrometry and separation science, as well as hands-on experience in quantitative LC-MS/MS analysis are desired. Proficiency in general computer software, including vendor specific instrument control and analysis tools, is required. Strong interpersonal and communication skills, both oral and written, are required as is commitment to working as a team player within a multifunctional organization. A working knowledge of allied disciplines such as computer science, lab automation, drug metabolism, pharmacokinetics and synthetic chemistry is helpful. Qualifications The successful candidate will also troubleshoot HPLC and MS instrumentation as necessary. LC-MS/MS analysis BS or MS in chemistry Additional Information Thanks & Regards Riya ************

Established in 1991, Collabera has been a leader in IT staffing for over 22 years and is one of the largest diversity IT staffing firms in the industry. As a half a billion dollar IT company, with more than 9,000 professionals across 30+ offices, Collabera offers comprehensive, cost-effective IT staffing & IT Services. We provide services to Fortune 500 and mid-size companies to meet their talent needs with high quality IT resources through Staff Augmentation, Global Talent Management, Value Added Services through CLASS (Competency Leveraged Advanced Staffing & Solutions) Permanent Placement Services and Vendor Management Programs. Collabera recognizes true potential of human capital and provides people the right opportunities for growth and professional excellence. Job Description •Assist Lead Biomarker Scientist to develop, optimize, validate, and perform FACS-based and other biomarker assays to support studies in New Haven CRU and external protocols if needed. •Performed general flow cytometry operation, including sample preparation and analysis. Experience in FACSCanto Flow Cytometer and FACSDiva software. •Performed quality control checks on Flow Cytometers and other Laboratory instruments, reagents, and techniques. •Operated, maintained, calibrated and trouble shoot Flow cytometers and other Laboratory instruments according to SOPs. •Maintained quality control and calibration logs of all Flow Cytometers. •Analyzed, summarized and document experimental results. •Performed data entry using laboratory information management system (LIMS) •Write experimental SOPs. •Update Biomarker Lead on the status, results and problems in method development and performance of the assays. •Complete all NHCRU/Pfizer required training. •Have a working knowledge of Microsoft office including Excel, Word and PowerPoint. •Possess multi-tasking and organizational skills. •Experience in ELISpot Assays and FlowJo software a plus. Qualifications MS in Biology/BioChemistry/Medical Technology plus 1 year of relevant experience BS in Biology/BioChemistry/Medical Technology or 3 years of relevant experience. Additional Information To schedule interview or get any further information feel free to contact: Sagar Rathore ************ ******************************

Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost. Job Description BS with 5+ year, MS with 2+ years experienced scientist to run flow cytometry clinical samples in a GCLP environment. In addition to running clinical samples, will also be involved for biomarker assay development and mechanistic studies. Ability to work occasional weekends for clinical sample analysis is required. Previous pharma and/or biotech experience preferred. Please list out the (up to) top three critical skills: 1. Cell-based and/or biomarker assay development 2, Flow cytometry 3. Cellular immunology Additional Information Best Regards, Anuj Mehta ************

The Associate Scientist will serve as the platform lead for Xenium spatial transcriptomics projects at Single Cell Biology Lab (SCBL) within The Jackson Laboratory for Genomic Medicine, ensuring the timely delivery of high-quality, robust data. The SCBL is a core facility supporting the scientific research community with cutting-edge single-cell technologies, including dissociative single-cell omics, spatial omics, and high-content screening. This role is central to the lab's spatial genomics capabilities, requiring deep expertise in the Xenium workflow, exceptional project coordination, and strong communication with scientific stakeholders. The ideal candidate will be the technical expert for all Xenium operations from sample handling and experimental execution to data quality control and workflow optimization. You will leverage your strong background in molecular biology, tissue handling, and single-cell technologies to enhance and expand the capabilities of the Single Cell Biology Lab. Key Responsibilities & Essential Functions Platform Leadership: Serve as the Xenium Platform Lead and Subject Matter Expert (SME), providing guidance and support to end-users and the broader scientific community. Project Management & Execution: Coordinate the full lifecycle of Xenium projects, including managing sample submission and receiving, providing service quotations, executing experiments, and ensuring final data quality control (QC). System Maintenance: Oversee instrument management, including maintaining the Xenium instrument, managing stock and inventory, and performing advanced troubleshooting of equipment and assays. Process Optimization & Development: Drive the continuous improvement of the platform by optimizing existing workflows and developing new spatial genomics capabilities and technologies. Scientific Awareness: Stay current with the newest developments in the spatial genomics field and effectively communicate technological updates to the team and research community. Meticulous Documentation: Maintain excellent documentation standards, including comprehensive lab notebooks, SOPs, error/work logs, metadata, and sample information. Stakeholder Communication: Ensure seamless communication with end-users, vendors, colleagues, and managers to coordinate and successfully complete all Xenium projects. Knowledge, Skills, and Abilities Required Education: Master's degree (M.S.) in Biology, Molecular Biology, or a related scientific field. Experience: 2-4 years of experience in a core facility or industry setting. Molecular & RNA Biology: Deep and comprehensive understanding of RNA and molecular biology principles, including associated assays. Imaging-Based Spatial Genomics Expertise: Hands-on experience with FISH-based platforms, including 10x Genomics Xenium, MERFISH, and seq FISH. Technical Breadth: Comprehensive knowledge of various spatial genomics technologies (e.g., Xenium, Visium, MERFISH, seq FISH). Sample Handling: Direct experience with tissue sectioning, handling, and immunohistochemistry (IHC) techniques. Documentation: Experience in writing Standard Operating Procedures (SOPs) and familiarity with Laboratory Information Management Systems (LIMS) and Electronic Lab Notebooks (ELN). Operational Skills: Proven project and lab management experience, including managing stock, inventory, and instrument uptime. Soft Skills: Exceptional communication, interpersonal, and presentation skills; proven ability to thrive as a team player within interdisciplinary groups. Preferred Education: Ph.D. preferred Single-Cell Experience: Hands-on experience with single-cell technologies (e.g., 10x Chromium, smart-seq, split-and-pool methods). Biopharma Industry Experience: Preferred experience working in an industrial setting, such as the biotechnology or pharmaceutical sector, demonstrating familiarity with industry-standard workflows and requirements. Histology Expertise: Experience in histopathology. Development: Proven track record in technology development or assay optimization. Pay Range: $69,711 - $90,624 #CA-NL6 About JAX: The Jackson Laboratory is an independent, nonprofit biomedical research institution with a National Cancer Institute-designated Cancer Center and nearly 3,000 employees in locations across the United States (Maine, Connecticut, California), Japan and China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health. Founded in 1929, JAX applies over nine decades of expertise in genetics to increase understanding of human disease, advancing treatments and cures for cancer, neurological and immune disorders, diabetes, aging and heart disease. It models and interprets genomic complexity, integrates basic research with clinical application, educates current and future scientists, and provides critical data, tools and services to the global biomedical community. For more information, please visit *********** . EEO Statement: The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.

Job Description Job Title: Senior Scientist / Associate Principal Scientist, Chemical Engineering R&D FLSA Status: Exempt Salary: $100,000-$160,0000 Pharmaron is a global CRO helping pharma and biotech companies bring new therapies to life. With over 21,000 employees worldwide across 23 locations in the US, UK and China, we support drug discovery through to manufacturing with fully integrated, high-quality services. We're proud of the impact we make and just last year, we supported over 780 discovery projects, 1,000+ CMC programmes, and 1,000+ clinical trials across all phases. Our teams are involved in everything from small molecules to biologics and gene therapies, and we work with more than 3,000 global customers. To learn more, visit ****************** About the Role The Pharmaron Process Chemistry department is seeking highly motivated Chemical Engineers for an exciting role involving hands-on small-molecule process development and scale-up from laboratory to commercial manufacturing. Engineers in this position will design, plan, and implement both chemistry laboratory and in-silico experiments to support process and technology development for active pharmaceutical ingredients (APIs). This position will combine elements of chemistry, engineering, technology development, and data analysis to optimize manufacturing processes. Strong teamwork, innovation, creativity, and organizational skills are essential, along with clear and confident communication to address technical challenges. Effective collaboration across multidisciplinary teams in the US, UK, and China, is critical, and a strong commitment to safety, quality compliance, and technical leadership is expected throughout all activities. Key Responsibilities Perform hands-on small molecule process development and scale-up work. Use Design of Experiments (DoE) for process screening, optimization, and robustness studies. Define CPPs, PARs, NORs, and contribute to the development of scalable control strategies. Apply process analytical technology (PAT) and process modeling. Evaluate and model kinetics, mixing, mass/heat transfer, and reactor performance. Conduct independent research to achieve mechanistic understanding for rational process design. Design and optimize key unit operations including crystallization, filtration, drying, distillation, and extraction. Use process modeling tools to inform scale-up strategies. Translate lab-scale findings into actionable parameters for kilo lab and GMP manufacturing. Drive cycle time reduction and process intensification initiatives. Implement innovative technologies such as continuous flow chemistry and automation platforms. Support internal and external tech transfer activities, including scale-up studies, modeling, and verification experiments. Support development of complex transformations such as catalytic hydrogenation. Exhibit a mindset of safety and quality compliance. Collaborate cross-functionally within US, UK, and China-based teams. Required Experience & Skills Education Minimum Requirement: The position requires either a BS and/or MS in Chemical Engineering (or comparable) from an accredited college/university plus at least 5 years of relevant work experience in small-molecule chemical process development - OR - a PhD in Chemical Engineering (or comparable) from an accredited college/university with at least 2 years of relevant work experience post PhD defense. Experience performing lab-based research/process development in a chemical engineering-related area. Experience with organic chemical synthesis and wet chemistry. Experience with small molecule pharmaceutical drug substance development. Experience applying statistical experimental design (i.e. Design of Experiments) and/or process modeling. A high level of innovation, creativity, and self-initiative. Highly effective communication and collaboration skills. Good organizational, interpersonal, writing, and time management skills. Preferred Experience & Skills Experience with process scale-up and/or technology transfer, moving from laboratory to pilot plant or production scale. Familiarity with concepts and application of cGMP and GDP during pharmaceutical development and production. Demonstrated experience with chemical engineering-related technology development. Familiarity with kilo-scale laboratory equipment. Experience with process modeling (e.g., population balance modeling, distillation modeling). Knowledge with milling equipment (spiral jet mills, pin mills, co-mills, rotor-stator wet mills). Why Pharmaron? Collaborative Culture: Thrive in our inclusive and collaborative environment, where teamwork and innovation go hand in hand. Here, your voice matters, and your contributions make a real impact. "Employees Number One" and "Clients Centered" are the core cultural values at Pharmaron. Our culture, which sets Pharmaron apart from other organizations, has evolved from our deep commitment to our employees, partners and collaborators. Benefits: As part of our commitment to your well-being, we offer a comprehensive benefits package: Insurance including Medical, Dental & Vision with significant employer contributions Employer-funded Health Reimbursement Account Healthcare & Dependent Care Flexible Spending Accounts 100% Employer-paid Employee Life and AD&D Insurance, Short and Long Term Disability Insurance 401k plan with generous employer match Access to an Employee Assistance Program How to Apply: Ready to seize this incredible opportunity? Join us at Pharmaron and be part of a dynamic team driving innovation and excellence in biopharmaceutical research and development. Apply online today! Pharmaron is a premier service provider for the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities and established a broad spectrum of research, development, and manufacturing service capabilities throughout the entire drug discovery, preclinical, and clinical development process across multiple therapeutic modalities, including small molecules, biologics, and CGT products. With over 21,000 employees and operations in the U.S., the U.K. and China. Pharmaron has an excellent track record in delivering R&D solutions to its partners in North America, Europe, Japan, and China. As an Equal Employment Opportunity and Affirmative Action employer, Pharmaron values diversity and inclusion in the workplace, fostering an environment where all individuals are empowered to succeed. Join us in our mission to make a difference in the world of life sciences.

Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost. Job Description: Primary Responsibilities: •Assist Lead Biomarker Scientist to develop, optimize, validate, and perform FACS-based and other biomarker assays to support studies in New Haven CRU and external protocols if needed. •Perform general flow cytometry operation, including sample preparation and analysis. Experience in FACSCanto Flow Cytometer and FACSDiva software. •Perform quality control checks on Flow Cytometers and other Laboratory instruments, reagents, and techniques. •Operate, maintain, calibrate and trouble shoot Flow cytometers and other Laboratory instruments according to SOPs. •Maintain quality control and calibration logs of all Flow Cytometers. •Analyze, summarize and document experimental results. •Perform data entry using laboratory information management system (LIMS) •Write experimental SOPs. •Update Biomarker Lead on the status, results and problems in method development and performance of the assays. •Complete all NHCRU/Pharmaceutical required training. •Have a working knowledge of Microsoft office including Excel, Word and PowerPoint. •Possess multi-tasking and organizational skills. •Experience in ELISpot Assays and FlowJo software a plus. Qualifications: Minimum of either MS in Biology/BioChemistry/Medical Technology plus 1 year of relevant experience BS in Biology/BioChemistry/Medical Technology or 3 years of relevant experience. Additional Information Best Regards, Anuj Mehta ************