Post job

Principal research scientist jobs in Manchester, NH

- 680 jobs
All
Principal Research Scientist
Scientist
Research And Development Scientist
Senior Food Scientist
Senior Research Associate Scientist
Senior Formulation Scientist
Assay Development Scientist
Senior Scientist
Associate Scientist, Research And Development
Senior Bioinformatics Scientist
Product Development Scientist
Research Scientist
Associate Research Scientist
Scientist Senior, Research And Development
  • Senior Scientist

    Alpha Consulting Corp 4.6company rating

    Principal research scientist job in Lexington, MA

    QUALIFICATIONS: • Bachelor's Degree within subject matter expertise required. • 18+ years' relevant experience required, or a master's degree with 12+ years' relevant experience, or a Doctoral degree with 6+ years' post-doctoral and/or industry-relevant experience can be considered. • Relevant required experience includes: Excellent understanding of ADME principles with knowledge of PK/PD modeling or biotransformation, highly desirable • Preferred experience includes: Prior experience working in a fully or hybrid ADME-outsourced models • Demonstrates excellent verbal and written communication skills. TOP SKILLS PER MGR: 1. Project-facing role (3+ years) 2. ADME or PKPD subject matter expert ESSENTIAL FUNCTIONS: • Function as DMPK project representative for global, cross-functional small molecule project teams to achieve project goals • Provide expert-level guidance to experimental plans and data interpretation with a strong expertise in either ADME/PK/DDI or PK/PD modeling and simulation • Troubleshoot highly complex tasks through independent and team-based efforts • Demonstrate deep subject matter expertise and in-depth experience, as well as creative, independent thinking and solutions for addressing critical scientific questions • Make independent decisions related to day-to-day experimental activities • Work closely with CROs to assume responsibility for DMPK experimental design, implementation, and interpretation • Analyze complex data with a high degree of sophistication, connect disparate datasets to reach conclusions, and communicate project updates and experimental results to relevant stakeholders • Ensure proper documentation of all experiments and data • Collaborative teamwork • Communicate regularly with international colleagues within the Client • Actively participate in cross-functional teams and meetings to drive project success • Achieve business goals, share learnings, knowledge, and skills & promote cross-functional teamwork • Share knowledge & expertise to expand team capabilities and goals • Demonstrate superior cross-cultural understanding to effectively interact with relevant stakeholders in the global organization • Write and review collaborative research manuscripts, project documents, and milestone documents • Complete assignments requiring expert-level knowledge of techniques and practices related to the research area • Represent the organization as NN-subject matter expert by attending and presenting at scientific conferences and global meetings
    $81k-124k yearly est. 15h ago
  • Senior Food Scientist

    Technosphere, Inc.

    Principal research scientist job in Ayer, MA

    MUST HAVES: Bachelor's degree in Food Science, Nutrition, or related field (Master's preferred; PhD or PharmD a plus). 5+ years of product development experience from concept to commercialization in nutrition, food, beverage, supplement, nutraceutical, or biotech industries. Previous experience in basic and applied research and development preferably in small/mid-sized nutrition, food, beverage and/or biotech company. Strong background in food science, ingredient interactions, and process impact on nutrient stability. Knowledge of food safety standards and aseptic processing
    $57k-95k yearly est. 3d ago
  • Machine Learning Scientist

    Acceler8 Talent

    Principal research scientist job in Cambridge, MA

    Machine Learning Scientist - LLM Systems for Scientific Discovery About the Team Join the internal AI initiative of a prominent venture studio that has launched 100+ life sciences companies (including Moderna). You'll be part of a ~20-person technical team in Cambridge building advanced LLM and ML systems that accelerate scientific breakthroughs and help launch new AI-first ventures. What Will I Be Doing: Research & prototype novel LLM workflows (agents, reasoning systems, tool-use frameworks) tailored to scientific applications Define success metrics and design custom benchmarks to evaluate AI systems across diverse scientific domains Collaborate with ML engineers to scale promising prototypes into production systems Stay at the frontier by synthesizing state-of-the-art research and validating findings through rigorous experimentation Build feedback loops that incorporate user testing into system development What We're Looking For: PhD in machine learning, computer science, statistics, physics, mathematics, or related quantitative field Research excellence in LLMs or adjacent areas (reasoning/agents, sequence modeling, representation learning, optimization) demonstrated through publications at top venues or impactful work Hands-on ML experience with PyTorch or JAX, including reproducible experiment workflows Strong Python skills and fluency with standard ML tools Ability to work independently while collaborating effectively in a small team Experience building LLM systems: agentic frameworks, RAG, multi-agent simulations, RLHF/DPO, or evaluation methodologies Domain knowledge in chemistry, biology, physics, materials science, or related fields What's in it for me: Competitive Compensation: $140k-$240k dependent on experience Work on originating and fostering breakthrough ventures transforming human health and sustainability Relocation assistance available (typically $10k sign-on bonus) Apply now for immediate consideration!
    $71k-103k yearly est. 15h ago
  • Senior Assay Development Scientist/Engineer

    Siphox Health

    Principal research scientist job in Burlington, MA

    +++ SiPhox Health is redefining clinical immunoassay diagnostics by miniaturizing the analytical power of a central lab into an accessible, affordable, at-home platform. Our silicon-photonics architecture unites advanced biochemistry, microfluidics, and semiconductor-grade manufacturing to deliver precise, multiplexed biomarker quantification in minutes on a device the size of a coffee maker. We are building what we believe will become the first mass-market photonic blood analyzer, enabling continuous improvement in chronic disease management through frequent, high-quality testing. +++ The Opportunity +++ We are looking for a Senior Assay Development Scientist or Engineer who wants to build assays that have never been built on this kind of platform before. If you thrive on developing rigorous, quantitative immunoassays, including challenging free/competitive assays, and want your work to directly ship in a consumer device used by millions, this is one of the rarest opportunities in diagnostics today. This role sits at the center of platform innovation, contributing directly to analytical chemistry, surface chemistry, microfluidics, and silicon photonics integration. You will shape a growing assay menu that spans hormones, inflammatory markers, metabolic proteins, and future pediatric/specialty panels. +++ What You'll Do +++ Core Assay Development Develop quantitative sandwich and competitive immunoassays (including free hormone assays, displacement-driven formats, and low-abundance biomarkers) on a silicon-photonic resonance platform. Design, execute, and interpret experiments focused on: Binding kinetics & equilibrium optimization Surface functionalization strategies Competitive assay dynamic-range shaping Calibrator and control development (matrix selection, commutability) Assay precision, stability, robustness Analytical Performance & Validation Own assay verification and validation aligned with CLSI standards (EP05, EP06, EP07, EP09, EP10, EP17). Establish and demonstrate performance for: Analytical sensitivity & functional limit (LoB/LoD/LoQ) Linearity & reportable range (including hook effects, competitive assay inflection characterization) Repeatability, reproducibility, and nested CV analysis Interference and cross-reactivity studies Matrix equivalency & recovery studies Build calibration models for a novel platform (e.g., 4PL/5PL, competitive curve inversion, chip-specific normalization frameworks). Cross-Functional Integration Collaborate deeply with photonics, microfluidics, reader electronics, manufacturing, and product engineering teams to close the loop on real-world assay performance. Work with process development and chemistry groups to scale assays from prototype to production, enabling high-volume, chip-based manufacturing. Documentation & Execution Deliver high-clarity technical reports, protocols, V&V documentation, and design-history file content that meets IVD and FDA expectations. Present results across the company to inform design decisions and product milestones. +++ What We're Looking For +++ Technical Background PhD + 2 years, or MS + 6 years in biochemistry, chemical engineering, analytical chemistry, biophysics, bioengineering, or related fields. Expertise in immunoassay development (sandwich and competitive). Experience with free hormone assays is a major plus. Demonstrated ability to independently solve complex analytical and biochemical problems. Hands-on experience with complex analytical workflows, assay automation, and instrumentation. Strong understanding of calibration design, commutability, and control strategies. Familiarity with statistical analysis of assay performance, including mixed-model ANOVA, CV decomposition, and method-comparison frameworks. Regulatory & Platform Experience (Bonus) Experience with IVD development, ISO 13485, or 21 CFR 820. Experience with POC or novel-platform assay development. Knowledge of label-free sensors, waveguides, or photonic resonance systems. Experience with Python, R, or MATLAB for data analysis, curve fitting, and automation. Personal Traits Strong scientific intuition paired with rigorous data discipline. Thrives in a fast-paced, milestone-driven startup environment. Creative problem solver willing to challenge established assay paradigms. High integrity, willingness to own outcomes, and a collaborative mindset. +++ Why This Role Is Unique +++ Most assay developers spend their careers optimizing assays on platforms that already exist. At SiPhox, you will: Build the first generation of photonic immunoassays deployed in consumer health. Design assays whose constraints are shaped by semiconductor physics as much as biochemistry. Work on hard problems (free hormone assays, multiplexing, competitive equilibrium, small-volume matrices) where innovation, not incrementalism, wins. See your work ship in a product used at home by real people, not just research labs. If you want to work at the frontier of diagnostics (where photonics, biochemistry, and consumer health converge) we'd love to meet you.
    $64k-94k yearly est. 2d ago
  • Research Scientist & Antibody Computational Analysis

    Massachusetts Eye and Ear Infirmary 4.4company rating

    Principal research scientist job in Cambridge, MA

    Site: The General Hospital Corporation Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. The DeKosky Laboratory for Immune Engineering and Drug Discovery (******************* Google Scholar: ************************************************************ is hiring a scientist to advance computational drug design and discovery, including the use of artificial intelligence (AI) and machine learning (ML) techniques. The hired candidate will focus on computational aspects of immune repertoire analyses of antibody functional screening data. These efforts will advance methods for rapid machine learning-based antibody drug design while developing new and improved antibody drug products. We are looking for enthusiastic individuals that are curious about computational drug discovery and immunology, and want to participate in the exciting world of diving deeply into understanding how computational data and molecular design can be applied to discovery new drugs and fight diseases. The selected candidate will join a dynamic research team at the forefront of antibody engineering. These projects are fully funded by the several organizations, including the US National Institutes of Health and collaborative projects with the Bill and Melinda Gates Foundation, with several ongoing efforts and new projects ready to begin. The Ragon Institute is an internationally renowned immunology-focused research center located in Kendall Square, Cambridge, Massachusetts, and with affiliations with MGH, Harvard, and MIT. This position is ideal for individuals who are interested in launching a career as biomedical research leaders in either academia or industry. Successful candidates will be immersed in a rich scientific community and become experts in advanced high-throughput drug development and establish cutting-edge drug screening approaches while being a part of a supportive, highly collaborative research environment with state-of-the-art facilities. The hired candidate will also be an affiliate of MIT, with access to MIT campus research resources and community facilities. Job Summary In consultation with their Principal Investigator (PI), undertake and execute a program of scientific study culminating in publication. Drives research projects scientifically and determines the course of research as evidenced by leadership, obtaining funding, writing, or other recognition. May not necessarily receive independent resources; however, their contribution is essential to the conceptual/scientific success of the project. They assist their PI in the training and supervision of other laboratory personnel and in a wide variety of administrative tasks, as necessary. Does this position require Patient Care? No Essential Functions -Makes proficient intellectual contributions to scientific strategies of the group/lab and plays a leadership role by acting as subject matter authority in the field. -Contributes to the design and execution of experiments and/or research projects. -Exercises judgment in selecting methods and technologies to obtain results. -May collaborate with external researchers and/or receive external project funding support. -Presents results and prepares publications. -May assist PI in the training and supervision of other staff. Qualifications Education Doctorate Related Field of Study required Can this role accept experience in lieu of a degree? No Licenses and Credentials Experience Previous Research experience (inclusive of graduate and postdoctoral experience) 5-7 years required Knowledge, Skills and Abilities - Excellent research skills. - Demonstrated evidence of specific scientific competence in field. - Demonstrated broad knowledge of field. - Evidence of potential for scientific creativity and original though. - Able to exercise independent judgment and leadership. - Ability to contribute to publications. Additional Job Details (if applicable) The salary range for this position is 80,000.00 to $105,000.00 annually. At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience, if applicable, education, certifications, and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums, and bonuses as applicable, and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package. Remote Type Onsite Work Location 600 Main Street Scheduled Weekly Hours 40 Employee Type Regular Work Shift Day (United States of America) EEO Statement: The General Hospital Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at **************. Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
    $105k yearly Auto-Apply 50d ago
  • Senior Research Associate/Associate Scientist, Preclinical Formulation Development

    Flagship Pioneering 3.6company rating

    Principal research scientist job in Cambridge, MA

    What if… you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies in order to transform health care and sustainability? Expedition Medicines Inc., is a privately held, early-stage biotechnology company pioneering the emerging field of Protein Editing. At Expedition Medicines we create small molecules that edit protein structure and function to unlock presently undruggable targets and a broad array of therapeutic modalities. Our platform integrates novel small molecule chemistry and chemoproteomic discovery technologies with Machine Learning (ML) to enable generative design. Expedition Medicines is backed by Flagship Pioneering, bringing their courage, vision, and resources to guide Expedition Medicines from platform validation to patient impact. We are seeking collaborative, relentless problem solvers that share our passion for impact to join us! THE ROLE The Formulation team is seeking a highly motivated, attentive and self-driven candidate to join our team and contribute to the development of discovery compounds as an Senior Research Associate/Associate Scientist. This successful candidate will join an energizing and collaborative research environment working as part of cross function drug discovery teams in providing a develop-ability assessment of innovative molecules. KEY RESPONSIBILITIES Execute stage appropriate, fit-for-purpose preclinical formulations preparation (Solutions, suspensions, emulsions, nanoparticles, SEDDS etc.) for oral, and parenteral formulations on a small scale for small molecules Author protocols describing preparation of formulations for use at internal and external formulation labs Basic drug substance characterization by using techniques such as HPLC/UPLC, XRPD, DSC and PLM. Assessment of the chemical and physical properties of small molecules, such as solubility, dissolution, particle size and chemical stability Routine lab support such as buffer and mobile phase preparation, pH meter calibration, basic troubleshooting of lab equipment, and coordinating with external instrument and service vendors. Shipping and receiving samples between internal and external sites Summarize experimental results and presents at team meetings and department presentations Author templated memos and reports with limited guidance Maintain detailed lab notebooks and reports in compliance with GLP/GMP guidelines (as applicable) Evaluate novel drug delivery systems (e.g., lipid-based, amorphous solid dispersions, spray dry etc.) for poorly soluble compounds Support transition of formulations from discovery to clinical development (e.g., bridging studies) Independently design and perform focused experiments that drive progress in cross-functional formulation initiatives PROFESSIONAL EXPERIENCE & QUALIFICATIONS B.S. or M.S. in Chemistry, Biochemistry, Chemical Engineering, or a related discipline is required Three years minimum of industry, government or equivalent experience in small molecules formulation or a related field Hands-on experience with one or more of the following techniques: HPLC, UV-visible, DSC etc Experience with data analysis using standard software platforms (Excel, Prism etc.) Practical experience in developing and preparing preclinical formulations (small molecules) Basic knowledge of physicochemical properties and their relationship to formulation development Basic knowledge of pharmacokinetics (PK) and biopharmaceutics principles The ability to manage multiple parallel activities and deliver results to agreed timelines Ability to do bench work independently Strong collaboration, problem-solving, and adaptability in fast-paced research environments Excellent written, oral, and visual communication skills Excellent time management skills LOCATION: Cambridge, MA ABOUT FLAGSHIP PIONEERING Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity's most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE's “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company's annual list of the World's Most Innovative Companies. Learn more about Flagship at *************************** At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact. We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship. Recruitment & Staffing Agencies : Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto. #LI-MB1 The salary range for this role is $81,000 - $126,500. Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. Expedition Medicines currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Expedition Medicine's good faith estimate as of the date of publication and may be modified in the future.
    $81k-126.5k yearly Auto-Apply 25d ago
  • Senior Food Scientist

    Blackstar 3.4company rating

    Principal research scientist job in Ayer, MA

    Are you passionate about creating innovative nutritional beverages and powders that make a real impact on health and wellness? We are seeking a Senior Food Scientist to lead the development and optimization of cutting-edge nutritional products from concept to commercialization. This role is perfect for a creative, detail-oriented scientist who thrives on innovation, quality, and clinical impact. Key Responsibilities: Develop, optimize, and scale nutritional beverage and powder formulations to meet sensory, nutritional, and stability goals. Collaborate with Medical Nutrition, Marketing, and Sales teams to align product development with business objectives and patient needs. Research and evaluate new ingredients and explore novel opportunities in medical nutrition. Provide scientific and technical expertise to support leadership in product and clinical development initiatives. Build and maintain strong vendor relationships to source high-quality ingredients that meet product specifications. Represent the company at scientific meetings, conferences, and industry events. Ensure protection of intellectual property for new products, formulations, and processes. Comply with all GMP, food safety, and workplace safety standards. Qualifications: Bachelor's degree in Food Science, Nutrition, or a related field (Master's preferred; PhD or PharmD a plus). 5+ years of product development experience from concept to commercialization in nutrition, food, beverage, supplement, nutraceutical, or biotech industries. Experience in both basic and applied R&D, preferably in small to mid-sized nutrition, food, beverage, or biotech companies. Strong expertise in food science, ingredient interactions, and process impact on nutrient stability. Knowledge of food safety regulations, aseptic processing, and quality standards. Excellent problem-solving, communication, and project management skills. Why Join Us: Competitive salary with a 12.5% performance-based bonus program Comprehensive health, dental, and vision insurance Paid time off and company holidays 401(k) plan with company match Opportunities for professional growth and career advancement Employee discounts on company products
    $52k-86k yearly est. 56d ago
  • Senior Causal AI Scientist, Research and Development

    Aitia

    Principal research scientist job in Cambridge, MA

    Job Description Senior Causal AI Scientist, Research and Development Aitia is the leader in the development and application of Causal AI and Digital Twins to discover the next generation of breakthrough drugs in neurodegenerative disorders, oncology, and immunology. By leveraging the convergence of multi-omic patient data, high-performance computing, and causal learning and AI, Aitia is revealing the hidden biological mechanisms of disease to create Digital Twins. Gemini Digital Twins are being used today to discover novel therapies and accelerate R&D in Alzheimer's Disease, Parkinson's Disease, Huntington's Disease, multiple myeloma, prostate cancer, and pancreatic cancer, with several more in development. Position Summary The Senior Scientist will join a dynamic Research and Development team to develop and continue scaling Aitia's powerful Causal AI and simulation platform and apply the platform to develop Gemini Digital Twins for the discovery of novel causal human drug targets and biomarkers and the simulation of drug candidates and clinical trials. The candidate will work closely with the Engineering Team on implementation of AI algorithms and with the Precision Medicine Team to develop Gemini Digital Twins. The candidate will develop and implement AI tools for automating priors, for integrating multi-omic data into Aitia's Digital Twins and for AI to automate extraction of features and novel biology. They will communicate scientific findings to partners and collaborators and contribute to presentations at scientific conferences and publications. Principal Duties and Responsibilities: Drive the effort to automate the building of Gemini Digital Twins by incorporating deep learning AI and LLMs into data and prior knowledge pipelines Drive the effort to automate through deep learning AI and LLMs the extraction of novel biology from the Gemini Digital Twins Contribute to cross-team efforts to build in silico patient causal AI models and research into novel model applications for neurodegenerative disorders and oncology therapeutic discovery and development Contribute to novel neurodegeneration and cancer genomics knowledge generation through deep data mining from public/proprietary multimodal datasets. Communicate technical results clearly and concisely to collaborations, discuss how to incorporate information into their processes, and achieve high impact with biopharmaceutical partners Job qualifications: Advanced degree in quantitative science or Life Science Experience working with advanced ML techniques, probability theory, Bayesian analysis, or causal inference methods preferred Solid understanding of statistical analysis principles and expert user of the statistical data analysis tools, such as Python R/Bioconductor or Python. Experience working with toolsets for automating AI and machine learning workflows. Experience working with AI stacks such as Torch Experience working with multi-omics data, single cell data, and high-throughput screening data Must be a team player and willing to help and ask for help; excellent written and verbal communication skills; excellent interpersonal skills with a proven record of interacting with bench scientists effectively. Company Culture Our philosophy at Aitia is simple: we cannot transform drug discovery and development with anything less than an all-star team. We are seeking smart, driven people who are experts in their field, have a track record of success, and a passion for creating change. We believe that strong teams supercharge the performance of individuals, create a fun and dynamic workplace, and provide first-class results for our clients and the people they serve. We are passionate about our work and believe in the ability of our technology to change the world. Our core values of integrity, collaboration, value, diversity, and game-changing initiatives guide our behaviors with each other and our clients. Aitia offers competitive salaries, stock options, unlimited vacation, health, dental and vision insurance, life insurance, long-term disability, 401(k), parental leave, tuition reimbursement, professional development, subsidized parking/MBTA pass, tasty food, volunteering opportunities, social gatherings, and more. Equal Employment Opportunity Aitia provides equal employment opportunities to all employees and applicants for employment without regard to race, color, national origin, religion, sexual orientation, gender, gender identity or expression, age, veteran status, disability, pregnancy or conditions related to pregnancy, or genetics. In addition to federal law requirements, Aitia complies with applicable state and local laws governing nondiscrimination in employment in every location in which the company has facilities. Powered by JazzHR XrwVxtACNV
    $90k-124k yearly est. 17d ago
  • BioPharmaceutical Opportunity for a Senior Research Associate | Research Scientist: BioPhysical Chemistry

    Vista Technology 3.6company rating

    Principal research scientist job in Woburn, MA

    . . . . . GROWTH OPPORTUNITY BIOPHYSICAL CHEMISTRY | BIOCHEMISTRY MISSION STATEMENT: Develop BioPhysical and Biochemical Assays for screening and characterizing small molecules. Do your skills include the following? Biophysical methods: SPR for determining small molecule affinity to protein targets Biochemical assays: develop, analyze and troubleshoot (e.g. FRET, FP, AlphaScreen/LISA, ADPGlo) Protein characterization techniques: size exclusion chromatography, dynamic light scattering, DSF, TSA If you are answering YES - - Reach out to learn more about this exciting new opportunity: Call: ************ or Schedule a time: ******************************** or Email: ************************* Visit our Company Website - ************************ Visit our Career Opportunities Page - *****************************
    $77k-113k yearly est. Easy Apply 60d+ ago
  • Product Development Scientist

    Ajinomoto Health & Nutrition North America

    Principal research scientist job in Ayer, MA

    About Us Eat Well, Live Well. At Ajinomoto Cambrooke, we build careers grounded in helping improve people's health through nutritional therapies. Ajinomoto Cambrooke (ACI) was founded by parents looking to develop better solutions for their children with PKU. Over the subsequent 25 years, we have expanded into additional therapeutic areas with a focus on enjoyable nutrition as a core part of normalizing the life for people living with medical conditions. Joining ACI means becoming part of a diverse team of talented people who want to build their careers while contributing back to society in a positive way. We seek individuals who bring an entrepreneurial mindset with a bias for action and finding solutions. We provide an environment based in mutual respect and collaboration to support you and give you opportunities to learn and develop. Join us to find a rewarding work experience that lets you be at your best and have an impact on our patient communities. Why Join Us Our people are the key ingredient to our success. We offer a collaborative, innovative environment where you can grow your career and make an impact on global food and health solutions. We provide a comprehensive and competitive total rewards package, including: • Competitive Pay and Annual Bonus Opportunity • 401(k) with Company Contributions • Medical, Dental, and Vision - Effective Day 1 • Paid Time Off, Company Holidays, and Floating Holidays • Paid Parental Leave • Wellness Programs and Yearly Wellness Reimbursement • Work Flexibility • Company-Paid Life and Disability Insurance • Employee Assistance Program (EAP) • Tuition Reimbursement Opportunities • Career Growth and Development within a Global Organization • Company-Provided Mental Health and Caregiving support Overview The Product Development Team supports the medical nutrition business by developing new and revising existing product formulations to meet target characteristics that will deliver positive patient outcomes through therapeutic nutrition. Strong collaboration with the Directors of Medical Nutrition, Marketing, and Sales will be required to ensure desired nutritional levels are achieved throughout the product shelf-life, patient insights on flavor, texture, and palatability are incorporated. In this role, you will contribute to the ideation and exploration for uses of new to ACI ingredients and new to ACI business ventures in additional disease-states reliant on specialized medical nutrition. This position sits in our Corporate Office located in Ayer, MA. Qualifications EDUCATION, CERTIFICATIONS AND EXPERIENCE: • Minimum bachelor's in food science, nutrition, or related field; Master's degree preferred. PhD, PharmD a plus. • 5+ years of experience in product development, with ability to take concepts from bench top to commercialization for nutritional beverages and / or nutritional powder blends from concept to commercialization. • 5+ years in basic and applied research and development preferably in small/mid-sized nutrition, food and/or biotech company. Experience with food/beverage formulation and manufacture of nutritional products that meet stability, sensory and nutritional requirements. Direct experience with aseptic processing / Tetra Pak a plus. • Expert scientific knowledge in food science with emphasis on product development involving interaction amongst ingredients and impact of process techniques on use of micro-nutrients. • Experience with nutritional modeling software and familiarity with FDA regulations preferred, exposure to EU regulations a plus. • Able to design and monitor product shelf-life procedures both regular and accelerated for nutritional products. • Strong translational science background with experience in converting basic nutrition-science insights into consumable products. KNOWLEDGE, SKILLS AND ABILITIES: • Build relationships with vendors to source ingredients to meet product specifications. • Overall understanding of how business units interact to facilitate successful product development and commercialization. • Ability to define new product needs in terms of process needs and product characteristics including organoleptic needs / claims • Demonstrated Leadership capability with a focus on innovation to drive product development proactively and passionately. • Exhibit the understanding of use of standard operation procedures related to product development, process development and product shelf-life determination. • Well versed with food safety requirements and regulations. • An understanding of human nutrition and ability to review primary scientific literature. • A strong ability to communicate basic science and technical challenges to non-technical audiences. • A strong understanding of ingredient interactions in a food/beverage matrix throughout processing and shelf life. • Ability to design shelf-life evaluation matrices considering product composition, process impact and other critical factors when designing new products in medical nutrition arena. • An understanding of macro and micro-nutrient analytical procedures and their principles. • Ability to work in a fast paced, cross functional team environment. • Excellent analytical skills, strong attention to details, good communication and interpersonal skills. • Excellent organizational skills, the ability to balance multiple projects, set priorities, and drive results. Working Conditions / Physical Requirements WORKING CONDITIONS: This position works in a food manufacturing environment and requires the ability to adhere to all GMP, Food Safety, workplace safety and security policies including wearing required personal protective equipment, as well hair net, beard net, etc. as required PHYSICAL REQUIREMENTS: Position requires the ability to occasionally lift up to 50 pounds, stand, walk, bend, reach, push, and pull. Ability to use a computer, keyboard, telephone, and other office equipment. Ability to wear all required PPE. Responsibilities • Utilize your exemplary food science and ingredient know-how to co-create and execute medical formula products against ACI's strategic R&D roadmap to support the overall corporate strategy while meeting the internal quality expectations. • Support the Leadership and Management teams with scientific support in the areas of product development, clinical development, product manufacturing and new ingredient compound / product initiatives. • Research and help develop clinical evidence supporting existing and new products and ingredient compounds for use in commercial activities. • Participate in conferences, clinician meetings and other forums to present ACI's clinical evidence. • Ensure existing and new products, processes or ingredient compounds have strong Intellectual Property protection thus providing ACI a sustained competitive advantage. • Other duties as assigned. Salary Range $105,000 - $130,000 Annual with potential 12.5% Bonus EEO Statement Ajinomoto Cambrooke, Inc. is an Equal Opportunity Employer-Vets/Disabled, committed to a diverse workforce. If you need assistance with completion of an application for employment, please contact Human Resources Department at ************.
    $105k-130k yearly Auto-Apply 51d ago
  • Associate Research Scientist

    Mindlance 4.6company rating

    Principal research scientist job in Waltham, MA

    The individual will play a key role in the identification and functional characterization of lead molecules across diverse therapeutic areas and modalities. Success in this role will involve working directly with multiple individuals in the Discovery Assays group on a weekly basis and can involve interactions with individuals throughout the larger Discovery organization. • Execute established plate based biochemical and cell-based screening assays for biologics hit ID • Execute assays for functional characterization of leads • Expand range of technical skills to cover range of assays used in hit identification and lead characterization within the group • Document experimental details and scientific findings, strong attention to detail; use LIMS system for workflow and experimental tracking, actively participate in scientific meetings Qualifications Specialized knowledge and skills • Experience with ELISA development, FACS, Luminex, Octet, Alpha Screen, HTRF or MSD is desirable • Experience with cell culture • Familiarity with automation, electronic lab notebook or LIMS systems a plus • Excellent organizational, analytical and technical skills are required along with ability to work well within a team environment • Enthusiasm, willingness to learn, strong work ethic, broad scientific interests § Excellent interpersonal and communication skills along with a sense of urgency and ability to work on multiple projects simultaneously Non-PhD candidates with at least 2 years of relevant work experience Additional Information Please Connect with me at ************
    $69k-95k yearly est. 5h ago
  • Machine Learning Scientist, AI Explainability

    SES 4.2company rating

    Principal research scientist job in Woburn, MA

    About Us: SES AI Corp. (NYSE: SES) is dedicated to accelerating the world's energy transition through groundbreaking material discovery and advanced battery management. We are at the forefront of revolutionizing battery creation, pioneering the integration of cutting-edge machine learning into our research and development. Our AI-enhanced, high-energy-density and high-power-density Li-Metal and Li-ion batteries are unique; they are the first in the world to utilize electrolyte materials discovered by AI. This powerful combination of "AI for science" and material engineering enables batteries that can be used across various applications, including transportation (land and air), energy storage, robotics, and drones. To learn more about us, please visit: ********** What We Offer: A highly competitive salary and robust benefits package, including comprehensive health coverage and an attractive equity/stock options program within our NYSE-listed company. The opportunity to contribute directly to a meaningful scientific project-accelerating the global energy transition-with a clear and broad public impact. Work in a dynamic, collaborative, and innovative environment at the intersection of AI and material science, driving the next generation of battery technology. Significant opportunities for professional growth and career development as you work alongside leading experts in AI, R&D, and engineering. Access to state-of-the-art facilities and proprietary technologies are used to discover and deploy AI-enhanced battery solutions. What we Need: The SES AI Prometheus team (AI Research) is seeking an exceptional Machine Learning Scientist to spearhead the development of our Large Language Models (LLM) and advanced AI agents. This role is pivotal in enabling groundbreaking research in machine learning for scientific discovery, particularly in the realm of material science and battery technology. Harness internal expertise and collaborate with external research labs to advance scientific ML. Work will be incorporated directly into our groundbreaking Deep Space multi-agent system for battery technology discovery. This position can be remote. Essential Duties and Responsibilities: Research & Development Lead cutting-edge research in machine learning for scientific discovery, with a focus on (multimodal) Large Language Models and their application (including AI agents) in battery and material discovery. Conduct groundbreaking research on integrating domain-specific data (including literature and internal documents) into LLM training and inference. Investigate the mechanisms through which LLMs approach problem-solving, planning, and solution generation, particularly in the context of basic battery design questions. Model Optimization & Implementation Troubleshoot and optimize the training process of large language models, addressing complexities and challenges related to data quality, model architecture, and computational efficiency. Implement innovative solutions to enhance model performance and scalability. Collaborate closely with a multidisciplinary team to integrate findings into practical AI solutions that contribute to the discovery of new battery materials and the advancement of lithium battery technology. Collaboration & Communication Contribute to academic and industry discussions by publishing research findings in top-tier journals and presenting at conferences. Engage in machine learning research aimed at addressing battery design challenges and enhancing system ability to interpret data-driven science efficiently. The ability to communicate complex concepts clearly and effectively to both technical and non-technical team members. Education and/or Experience: MS or PhD in Computer Science, Statistics, Computational Neuroscience, Cognitive Science or a related field, or equivalent practical experience. Strong foundational knowledge and practical experience in Machine Learning, Deep Learning, and Large Language Models. Proficiency in programming languages relevant to machine learning, with a strong preference for Python. Experience with deep learning frameworks such as PyTorch or TensorFlow. Proficiency in utilizing causal graphs for AI research and application. A solid track record of innovative research, preferably with published work in relevant areas. Excellent problem-solving abilities and a passion for tackling complex technical challenges. Preferred Qualifications: Experience with AI applications in material science or battery technology. Familiarity with the latest trends and methodologies in AI research, including algorithms such as GRPO.
    $70k-103k yearly est. Auto-Apply 16d ago
  • Scientist - Process Research & Development

    Veranova, L.P

    Principal research scientist job in Devens, MA

    Discover Veranova: At Veranova, we believe people are our most important asset, and we are dedicated to building the most talented workforce in our industry. Our commitment to uncompromising focus on quality, compliance, safety, and excellence in delivery shapes everything we do. We are not just looking for skills; we are seeking innovative individuals who have a mindset open to learning and growth, and a desire to make a difference. Veranova is a global leader in the development and manufacturing of complex active pharmaceutical ingredients (APIs) for pharma and biotech customers. With deep technical expertise and impressive flexibility, we develop solutions and processes that support and accelerate innovation. Join us on our mission to enable current and next-generation therapeutics to improve and save the lives of patients. Role Overview: The Process R&D Scientist plays a key role in developing and optimizing synthetic routes for complex active pharmaceutical ingredients (APIs). This position conducts small- to large-scale chemical reactions and generates high-quality data that supports project decision-making and innovation. Working under the guidance of technical leads, the role contributes to delivering projects on time, on spec, and within budget. It's an excellent opportunity to deepen expertise while supporting impactful pharmaceutical development. Core Responsibilities: Delivers experimental output with high scientific integrity, meeting targets, timelines, and quality expectations with guidance. Exhibits strong safety awareness, conducts laboratory and operational activities safely, and maintains accountability for safe behavior in the work environment. Maintains technical equipment and related services to ensure proper functionality. Acts on feedback and demonstrates a continuous commitment to learning and professional development. Leads technical and operational areas and supports troubleshooting for complex scientific issues with minimal guidance. Shares knowledge, skills, and experience effectively with internal and external stakeholders; may lead focused projects as a key contact. Keeps accurate, legible, and complete records of all experiments, observations, and equipment use. Writes high-quality reports and delivers presentations to customers and management with some guidance, aligned with project milestones. Contributes to maintaining strong customer relationships and identifies new commercial opportunities. Actively supports the technical development of the department and the broader organization. Ensures all documentation meets Veranova standards; supports audit readiness and participates in regulatory and customer audits as needed; reports near misses and safety incidents per company procedures; and ensures all work complies with applicable state and federal regulations, including GMP, DEA, and FDA requirements. Adheres to all EHS policies and procedures; demonstrates strong technical and procedural proficiency in applying EHS standards; supports EHS audit readiness and participates in audits; reports and cooperates fully in investigations of near misses and incidents; and upholds Veranova's EHS commitments by integrating ISO 14001, OHSAS 18001, and Sustainability 2025 principles into daily work. Performs additional duties within the employee's skills and abilities as reasonably assigned. Qualifications: Required PhD degree (or equivalent experience) in a chemistry related discipline. Proficiency with relevant lab and analytical techniques. Previous industry experience in relevant areas. Proficiency with relevant analytical techniques within an industry environment. Ability to write clear and concise technical reports. Good understanding of Microsoft Office and other relevant technical software platforms. Skilled in written and spoken communication and proven ability to effectively interact with management. Demonstrates good judgment, quick decision-making skills, and the ability to work independently and in a team environment. Special Factors Must be able to stand, walk, and manually operate objects, tools, or controls; reach with hands or arms; and climb, balance, stoop, kneel, or crouch when necessary for the job activity. Must be able to lift and/or move up to 50 pounds. Specific vision abilities include near, distance, peripheral, color perception, and the ability to adjust focus. May regularly work with moving mechanical parts and may work with toxic or caustic chemicals. May work in humid areas with low or high temperatures. May be required to work with a respirator or operate with full-body Tyvek suits and supplied air or PAPR. Salary Range : $105,000 - $120,000 annual base salary Our Commitment: Health & Wellness: Comprehensive health & wellness benefits. Access to mental health resources and wellness programs. Generous PTO and holiday pay policies. Financial Wellness: Veranova is committed to fair and transparent compensation practices. This includes a competitive base salary, eligibility for performance-based bonuses, and an attractive 401(k) Plan with company match. Salary ranges reflect the scope and expectations of the role, and are based on market data, internal equity, and role-specific factors. Final compensation may vary depending on experience, skills, education, and business needs. Professional Development: Opportunities for continuous learning through LinkedIn Learning, workshops, conferences, and mentorship. Tuition Assistance for Undergraduate and Graduate degree programs. Inclusive Culture: At Veranova, an inclusive culture is integral to our values. We welcome people with diverse experiences and perspectives who share our mission to improve and save lives. Even if you don't meet every qualification, we encourage you to apply. Veterans, first responders, and those transitioning from military to civilian life bring valuable skills that strengthen our team. Additional Information: Applicants for this role must be authorized to work in the United States without further employer sponsorship. Agency and Search Firm Representatives: Veranova does not accept unsolicited resumes from agencies and/or search firms for this job posting. All your information will be kept confidential according to EEO guidelines. Veranova is an Equal Opportunity Employer. It is the policy of Veranova to provide equal employment access and opportunity to all persons regardless of age, race, color, national origin, religion, sex, sexual orientation, gender identity and/or expression, physical or mental disability, genetic information, citizenship, marital status, veteran status, or any other characteristic protected by federal, state, or local law. All applications are carefully considered, and your details will be stored on our secure Application Management System. This is used throughout Veranova for the selection of suitable candidates for our vacancies as they arise. Veranova respects your privacy and is committed to protecting your personal information. For more information about how your personal data is used please view our privacy notice. #LI-Onsite
    $105k-120k yearly Auto-Apply 8d ago
  • Research Associate/Associate Scientist, Assay Development

    Spear Bio

    Principal research scientist job in Woburn, MA

    Spear Bio, founded in 2021, is a well-funded and rapidly growing biotech start-up headquartered in Woburn, Massachusetts. Our proprietary technology, Successive Proximity Extension Amplification Reaction (SPEAR), is a novel wash-free immunoassay platform, offering unprecedented sensitivity. We are dedicated to revolutionizing early disease diagnosis and monitoring by providing scalable, ultrasensitive solutions that deliver unparalleled accuracy in measuring low-abundant biomarkers, enabling clinicians and researchers to improve patient outcomes and advance global health. Research Associate/Associate Scientist: We are seeking a highly motivated and experienced Research Associate/Associate Scientist to join our growing Assay Development team, with hands-on experience running ultrasensitive immunoassays and the desire to be at the forefront of innovative research. This individual will play a pivotal role in advancing Spear Bio's new range of ultrasensitive immunoassays and assay biomarker programs. This role is based onsite in our lab in Woburn, MA 5 days/wk. Responsibilities: Test and execute immunoassay workflows on high-throughput, semi-automated platforms Assist in optimizing methods for processing different types of biofluid samples (ie. serum, plasma) for assay development Set up, calibrate, and maintain laboratory equipment, as specified by the requirements of various projects Assist in data analysis Acquire necessary equipment and supplies for various projects Qualifications: Master's degree in Biology, Biochemistry, Biophysics, Biomedical Engineering or a related discipline plus 1-3 years of assay development experience in an industry or academic lab Direct experience running biofluid-based immunoassays and qPCR experimentation is required Experience with neurodegenerative disease protein biomarkers a plus (ie. pTau217, pTau181, NFL, GFAP, alpha-synuclein, etc.) Experience characterizing and troubleshooting immunoassays Strong proficiency in molecular biology lab techniques General Qualifications: Self-motivated and ability to perform complex tasks in an effective manner Ability to follow instructions and grow in a mentorship setting Excellent organizational and documentation skills Desire to learn and implement new technologies Strong presentation and interpersonal skills, ability to build collaborative working relationships, and become a key contributor within the assay development team Work 5 days/week on site in Woburn, MA. LOCAL CANDIDATES will be given priority consideration for this position. We offer competitive compensation, meaningful stock ownership, comprehensive benefits, and a great work environment. This is an opportunity to enter an innovative, high-growth startup at an early stage and play an integral role in the company's growth and success. We are focused on identifying candidates who have demonstrated leadership and excellence throughout their careers and are excited by the prospect of building an industry-leading company. Spear Bio Inc. provides equal opportunity in employment to all persons. No person shall be denied equal access because of race, creed, color, religion, national origin, sex, sexual orientation, gender identity, age, or physical/mental disability. Spear Bio does not accept resume submissions from external recruiting agencies. Any unsolicited resumes or candidate information submitted without prior written agreement will be deemed the property of Spear Bio, and no placement fees will be paid.
    $69k-97k yearly est. Auto-Apply 5d ago
  • Scientist I

    Boston Analytical 4.2company rating

    Principal research scientist job in Salem, NH

    Job DescriptionSalary: The Scientist will contribute to Extractables & Leachables studies performed in the E&L laboratory at Boston Analytical to support client submissions. The ideal candidate will have experience operating LC-MS and GC-MS systems for analysis of volatile, semi-volatile, and nonvolatile organic extractables and leachables samples. PRIMARY DUTIES AND RESPONSIBILITIES Prepares extractions for analysis. Analysis of sample extract solutions by GC-MS and LC-MS to adequately resolve and identify all compounds. Coordinate findings with the team to generate conclusions. Author detailed cGMP report sections for work performed outlining study findings. Develop analysis methods for drug product leachables testing. Performs system maintenance and calibrations to ensure equipment is operating with specified requirements. Ensures all work performed strictly adheres to Company, client and Pharmacopial requirements. Proper handling of hazardous waste in compliance with the Company and DES hazardous waste rules. REQUIREMENTS & QUALIFICATIONS Qualification includes a Ph.D. in Analytical Chemistry with 2+ years experience or a Masters degree and 4+ years experience or a Bachelors with 6+ years of experience performing and interpreting MS analysis. Knowledge of current Extractable & Leachables guidance (USP, ISO 10993) and best practices preferred. Experience working in a cGMP environment required. MINIMUM SKILLS REQUIREMENTS Must have the ability and skill to perform the detailed job requirements noted above competently, safely and proficiently. A self-starter, motivated person who possesses good interpersonal skills capable of effectively interacting with all departments and client personnel. Must have excellent organizational, verbal communication and technical writing skills. Must be a team player with integrity and concern for the quality of Company products, services and staff members. Demonstrated LC-MS and/or GC-MS operation and data interpretation capability. Ability to develop and optimize HPLC, UPLC, and GC methods. Documented success managing complex projects to completion within customer expectations for deadline, cost, and overall deliverable
    $63k-93k yearly est. 8d ago
  • Behavior Scientist

    Greater Lawrence Family Health Center 3.9company rating

    Principal research scientist job in Lawrence, MA

    Established in 1980, the Greater Lawrence Family Health Center, Inc. (GLFHC) is a multi-site, mission-driven, non-profit organization employing over 700 staff whose primary focus is providing the highest quality patient care to a culturally diverse population throughout the Merrimack Valley. Nationally recognized as a leader in community medicine (family practice, pediatrics, internal medicine, and geriatrics), GLFHC has clinical sites in Lawrence, Methuen, and Haverhill and is the sponsoring organization for the Lawrence Family Medicine Residency program. About Lawrence Family Medicine Residency Program: GLFHC was the first federally-qualified community health center in the United States to host a teaching residency program. Started in 1994, the Lawrence Family Medicine Residency is accredited through GLFHC and is affiliated with Lawrence General Hospital. From 1994 through 2021, LFMR has 210 physician graduates. While most family medicine residency programs are three years in length, LFMR is a four-year training program that is part of a national pilot looking at training innovation. Residents spend an extra year of training to further expand their scope of practice, particularly in an area of concentration, and to develop further expertise in population health, health systems management and leadership, and integrating that care into communities. Resident physicians also participate in a nationally recognized curriculum where they learn to speak and provide medical care in Spanish. The goal of the training program is to train family physicians who provide comprehensive primary care to vulnerable populations and can improve the health and health equity of these communities.   GLFHC is currently seeking a Behavior Scientist. The Behavior Scientist teaches family residents on an individual basis, in group settings including didactic lectures, workshops, and seminars on behavioral science topics. Assists in the development and implementation of a family medicine behavioral science curriculum and professional development activities for family medicine residents. Provides residents with skills needed to maintain their commitment to practicing high quality patient-focused care within a high stress work environment. Ensures compliance with ACGME behavioral science/professional development requirements for family medicine residents. Provides residents with the tools necessary to develop the skills needed to work effectively with underserved and multi-ethnic populations. Provides clinical services in the outpatient setting inclusive of diagnostic and crisis assessment, psychological education and intervention, individual and systematic interventions and health and behavior coaching. Qualifications Experience with Family Medicine residency medical education. Experience in providing integrated care with a team of physicians and a track record of working with teams of health care providers and support staff from different disciplines. Experience providing psychotherapy to a socioeconomically challenged and ethnically underprivileged community Interest in conducting research consistent with the complexity of issues that arise in primary care and the delivery of integrated care and associated curricular development. Massachusetts state license. Expertise with motivational interviewing and cognitive behavioral therapy techniques. Bilingual in Spanish preferred (faculty development in Spanish language learning is available) Education Ph.D. or Psy.D. in Psychology, or LICSW with expertise in individual and family therapy. GLFHC offers a setting that's flexible, rewarding and challenging. If you want to make an impact to the community we serve, apply today!
    $79k-102k yearly est. 60d+ ago
  • Senior Food Scientist

    Technosphere, Inc.

    Principal research scientist job in Ayer, MA

    Job Tittle: Senior Food Scientist Work Authorization : US Citizen and Green Card This role will lead the development and improvement of nutritional beverages and powders from concept to commercialization, driving innovation that ensures exceptional quality, stability, and clinical impact. Responsibilities Develop and optimize nutritional beverage and powder formulations that meet nutritional, sensory, and stability goals. Partner with Medical Nutrition, Marketing, and Sales to align product design with business and patient needs. Research and evaluate new ingredients and explore new medical nutrition opportunities. Support leadership with technical and scientific expertise for product and clinical development. Build vendor relationships to source ingredients that meet product requirements. Present company research at scientific meetings and conferences. Ensure strong intellectual property protection for new products and processes. Follow all GMP, food safety, and workplace safety policies. MUST HAVES: Bachelor's degree in Food Science, Nutrition, or related field (Master's preferred; PhD or PharmD a plus). 5+ years of product development experience from concept to commercialization in nutrition, food, beverage, supplement, nutraceutical, or biotech industries. Previous experience in basic and applied research and development preferably in small/mid-sized nutrition, food, beverage and/or biotech company. Strong background in food science, ingredient interactions, and process impact on nutrient stability. Knowledge of food safety standards and aseptic processing AI-generated to support your search process-please use them as guidance and apply your own best judgment when making decisions Benefits Competitive salary and performance-based bonus (12.5%) program Comprehensive health, dental, and vision insurance Paid time off and holidays 401(k) with company match Opportunities for professional growth and advancement Employee discount programs
    $57k-95k yearly est. 3d ago
  • Senior Research Associate/Associate Scientist, Preclinical Formulation Development

    Flagship Pioneering, Inc. 3.6company rating

    Principal research scientist job in Cambridge, MA

    What if… you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies in order to transform health care and sustainability? Expedition Medicines Inc., is a privately held, early-stage biotechnology company pioneering the emerging field of Protein Editing. At Expedition Medicines we create small molecules that edit protein structure and function to unlock presently undruggable targets and a broad array of therapeutic modalities. Our platform integrates novel small molecule chemistry and chemoproteomic discovery technologies with Machine Learning (ML) to enable generative design. Expedition Medicines is backed by Flagship Pioneering, bringing their courage, vision, and resources to guide Expedition Medicines from platform validation to patient impact. We are seeking collaborative, relentless problem solvers that share our passion for impact to join us! THE ROLE The Formulation team is seeking a highly motivated, attentive and self-driven candidate to join our team and contribute to the development of discovery compounds as an Senior Research Associate/Associate Scientist. This successful candidate will join an energizing and collaborative research environment working as part of cross function drug discovery teams in providing a develop-ability assessment of innovative molecules. KEY RESPONSIBILITIES * Execute stage appropriate, fit-for-purpose preclinical formulations preparation (Solutions, suspensions, emulsions, nanoparticles, SEDDS etc.) for oral, and parenteral formulations on a small scale for small molecules * Author protocols describing preparation of formulations for use at internal and external formulation labs * Basic drug substance characterization by using techniques such as HPLC/UPLC, XRPD, DSC and PLM. Assessment of the chemical and physical properties of small molecules, such as solubility, dissolution, particle size and chemical stability * Routine lab support such as buffer and mobile phase preparation, pH meter calibration, basic troubleshooting of lab equipment, and coordinating with external instrument and service vendors. Shipping and receiving samples between internal and external sites * Summarize experimental results and presents at team meetings and department presentations * Author templated memos and reports with limited guidance * Maintain detailed lab notebooks and reports in compliance with GLP/GMP guidelines (as applicable) * Evaluate novel drug delivery systems (e.g., lipid-based, amorphous solid dispersions, spray dry etc.) for poorly soluble compounds * Support transition of formulations from discovery to clinical development (e.g., bridging studies) * Independently design and perform focused experiments that drive progress in cross-functional formulation initiatives PROFESSIONAL EXPERIENCE & QUALIFICATIONS * B.S. or M.S. in Chemistry, Biochemistry, Chemical Engineering, or a related discipline is required * Three years minimum of industry, government or equivalent experience in small molecules formulation or a related field * Hands-on experience with one or more of the following techniques: HPLC, UV-visible, DSC etc * Experience with data analysis using standard software platforms (Excel, Prism etc.) * Practical experience in developing and preparing preclinical formulations (small molecules) * Basic knowledge of physicochemical properties and their relationship to formulation development * Basic knowledge of pharmacokinetics (PK) and biopharmaceutics principles * The ability to manage multiple parallel activities and deliver results to agreed timelines * Ability to do bench work independently * Strong collaboration, problem-solving, and adaptability in fast-paced research environments * Excellent written, oral, and visual communication skills * Excellent time management skills LOCATION: Cambridge, MA ABOUT FLAGSHIP PIONEERING Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity's most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE's "Change the World" list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company's annual list of the World's Most Innovative Companies. Learn more about Flagship at *************************** At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact. We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship. Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, "FSP") do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto. #LI-MB1 The salary range for this role is $81,000 - $126,500. Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. Expedition Medicines currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Expedition Medicine's good faith estimate as of the date of publication and may be modified in the future.
    $81k-126.5k yearly Auto-Apply 57d ago
  • Phosphoramidite Scientist - Process R&D

    Veranova, L.P

    Principal research scientist job in Devens, MA

    Discover Veranova: At Veranova, we believe people are our most important asset, and we are dedicated to building the most talented workforce in our industry. Our commitment to uncompromising focus on quality, compliance, safety, and excellence in delivery shapes everything we do. We are not just looking for skills; we are seeking innovative individuals who have a mindset open to learning and growth, and a desire to make a difference. Veranova is a global leader in the development and manufacturing of complex active pharmaceutical ingredients (APIs) for pharma and biotech customers. With deep technical expertise and impressive flexibility, we develop solutions and processes that support and accelerate innovation. Join us on our mission to enable current and next-generation therapeutics to improve and save the lives of patients. Role Overview: The Scientist role within the Chemical Development group will focus on the synthesis, process development, and analytical strategy for protected phosphoramidite precursors used in therapeutic oligonucleotide API manufacturing. This position is key to building Veranova's commercial capability in producing high-quality oligonucleotide building blocks. The ideal candidate will have strong expertise in phosphoramidite chemistry, including impurity profiling and customer-specific requirements. This role will also collaborate closely with the Analytical Team to establish robust characterization and control strategies that ensure exceptional product quality. Core Responsibilities: Develop and optimize synthetic routes for protected Phosphoramidite subunits used in therapeutic oligonucleotide API synthesis. Identify and mitigate side reactions commonly associated with Phosphoramidite chemistry. Define and implement specifications aligned with customer expectations for commercial-grade oligonucleotide precursors. Provide expert guidance to the Analytical Team on the selection and application of appropriate analytical methods for product and impurity characterization, based on prior experience and industry standards. Collaborate with cross-functional teams including Analytical Development, Quality, and Manufacturing to ensure successful scale-up and tech transfer. Prepare technical documentation including batch records, specifications, and development reports in accordance with SOPs and cGMP guidelines. Present scientific findings and project updates to internal stakeholders and external customers. Support the establishment of quality and regulatory standards for commercial production of oligonucleotide precursors. Contribute to project planning, budgeting, and timeline management for precursor development programs. Other duties as assigned. Qualifications: Required BS in Organic Chemistry or equivalent with 3-5 years related experience in a pharmaceutical industry, or MS in Organic Chemistry or equivalent with 0-2 years related experience in the pharmaceutical industry. Ability to read, analyze, and interpret English-language chemical periodicals, scientific journals, and regulatory documents. Experience with organic synthesis and process development Experience with common analytical techniques such as HPLC, GC, NMR, UV, and LC-MS. Experience in establishing integrated plans with defined resources and tasks. Ability to write clear and concise technical reports. Good understanding of Microsoft Office and statistical software. Demonstrate ability to exercise good judgment and make decisions quickly. Good written and verbal communication skills. Ability to work independently and in a team environment. Salary Range : $110,000 - $120,000 annual base salary Our Commitment: Health & Wellness: Comprehensive health & wellness benefits. Access to mental health resources and wellness programs. Generous PTO and holiday pay policies. Financial Wellness: Veranova is committed to fair and transparent compensation practices. This includes a competitive base salary, eligibility for performance-based bonuses, and an attractive 401(k) Plan with company match. Salary ranges reflect the scope and expectations of the role, and are based on market data, internal equity, and role-specific factors. Final compensation may vary depending on experience, skills, education, and business needs. Professional Development: Opportunities for continuous learning through LinkedIn Learning, workshops, conferences, and mentorship. Tuition Assistance for Undergraduate and Graduate degree programs. Inclusive Culture: At Veranova, an inclusive culture is integral to our values. We welcome people with diverse experiences and perspectives who share our mission to improve and save lives. Even if you don't meet every qualification, we encourage you to apply. Veterans, first responders, and those transitioning from military to civilian life bring valuable skills that strengthen our team. Additional Information: Applicants for this role must be authorized to work in the United States without further employer sponsorship. Agency and Search Firm Representatives: Veranova does not accept unsolicited resumes from agencies and/or search firms for this job posting. All your information will be kept confidential according to EEO guidelines. Veranova is an Equal Opportunity Employer. It is the policy of Veranova to provide equal employment access and opportunity to all persons regardless of age, race, color, national origin, religion, sex, sexual orientation, gender identity and/or expression, physical or mental disability, genetic information, citizenship, marital status, veteran status, or any other characteristic protected by federal, state, or local law. All applications are carefully considered, and your details will be stored on our secure Application Management System. This is used throughout Veranova for the selection of suitable candidates for our vacancies as they arise. Veranova respects your privacy and is committed to protecting your personal information. For more information about how your personal data is used please view our privacy notice. #LI-Onsite
    $110k-120k yearly Auto-Apply 23d ago
  • Pioneering Medicines:Senior Scientist Bioinformatics

    Flagship Pioneering 3.6company rating

    Principal research scientist job in Cambridge, MA

    What if... We could harness the power of Flagship's scientific platforms and create novel treatment options that benefit more patients, sooner? Pioneering Medicines, a division of Flagship Pioneering, is building a world-class biopharmaceutical R&D capability focused on conceiving and developing life-changing treatments for patients by harnessing the power of Flagship's scientific platforms and applying those innovative approaches to serious diseases with unmet medical need. Unique to Pioneering Medicines' approach is the opportunity to combine platforms to create truly novel and potentially transformative treatments. About Flagship Pioneering: Flagship Pioneering conceives, creates, resources, and develops first-in-category life science platform companies to transform human health and sustainability. Since its founding in 2000, the firm has originated and fostered the development of more than 100 scientific ventures, resulting in over $34 billion in aggregate value, 500+ issued patents, and more than 50 clinical trials for novel therapeutic agents. Position Summary: We are seeking a highly capable bioinformatics expert, with experience in applying computational methods to biological data, to join our Translational Sciences team. The successful candidate will step into active therapeutic programs and operate with a high degree of independence, helping drive bioinformatics strategy from early discovery through translational development. This role is well-suited for individuals who combine scientific depth with strong computational acumen and thrive in dynamic, cross-functional environments. The position offers room for growth, with flexibility to consider more senior candidates who demonstrate the ability to lead program-level bioinformatics strategy and cross-functional integration. Key Responsibilities: Lead computational biology efforts within active therapeutic programs, working across disease areas such as oncology, immunology, metabolic, or rare diseases. Analyze and integrate omics data types (e.g., bulk/single-cell RNA-seq, proteomics, spatial transcriptomics, genomic variation) to inform target discovery, biomarker development, and patient segmentation. Translate biological questions into analytical strategies, influence experimental design, and generate actionable insights for interdisciplinary teams. Coach other team members on strategic thinking and next level synthesis and communication skills. Apply machine learning and AI approaches to uncover novel insights, including dimensionality reduction, clustering, classification, predictive modeling, and network-based inference. Stay current with relevant computational trends (e.g., multi-modal learning, foundation models, causal inference) and propose their application to Pioneering Medicines programs. Communicate findings effectively to both technical and non-technical stakeholders, contributing to program direction and decision-making. Serve as a computational thought partner to scientific leadership across programs. Required Qualifications: Ph.D. in Bioinformatics, Computational Biology, Biological Sciences, Computer Science, or related field. 3-6 years of relevant industry experience, ideally with direct exposure to therapeutic discovery programs. Understanding of biology and/or translational research and ability to address biological questions using computational approaches. Strong experience analyzing next-generation sequencing data (e.g., bulk/single-cell RNA-seq, WGS/WES, ATAC-seq). Proficiency in Python and/or R, and experience with cloud-based computing (AWS, Terra, Code Ocean). Demonstrated application of AI/ML to biological datasets, including algorithm development or use of libraries like scikit-learn, XGBoost, Pinnacle. Familiarity with biological interpretation of omics data, pathway analysis, and network inference. Ability to work independently, manage priorities across programs, and influence program strategy. Excellent communication and collaboration skills; experience working in matrixed teams. Preferred: Exposure to translational science, patient stratification, or biomarker discovery in preclinical or clinical contexts. Experience integrating heterogeneous omics data. Knowledge of experimental design and data QC best practices. Prior experience in biotech or pharma. Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. Recruitment & Staffing Agencies : Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto. #LI-TD1 The salary range for this role is $163,000 - $214,500. Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. Pioneering Medicines currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Pioneering Medicines's good faith estimate as of the date of publication and may be modified in the future.
    $64k-99k yearly est. Auto-Apply 25d ago

Learn more about principal research scientist jobs

How much does a principal research scientist earn in Manchester, NH?

The average principal research scientist in Manchester, NH earns between $68,000 and $134,000 annually. This compares to the national average principal research scientist range of $87,000 to $184,000.

Average principal research scientist salary in Manchester, NH

$96,000
Job type you want
Full Time
Part Time
Internship
Temporary