AI Machine Learning Scientist
Principal research scientist job in San Diego, CA
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We seek a highly qualified, motivated Scientist with a strong background in machine learning/generative AI to join the AI Platform at Sanford Laboratories for Innovative Medicine (Sanford Labs). Sanford Labs is an independent, not-for-profit biomedical research organization with a mission to discover and deliver the next generation of molecular medicines.
RNA therapeutics are a rapidly expanding class of modalities (e.g., ASOs, si RNAs, mRNAs, and RNA aptamers) that can enable rapid clinical solutions. At Sanford Labs, you will help develop and implement AI/ML models and optimization paradigms to design best-in-class RNA therapeutics. As a Machine Learning Scientist, you will focus on designing and optimizing advanced AI/ML algorithms to address complex challenges in RNA therapeutics. You will develop and implement state-of-the-art architectures to enhance RNA sequence design, collaborating closely with interdisciplinary teams across Sanford Labs. This position offers an exciting opportunity to apply and refine cutting-edge machine learning methods while advancing innovative therapeutic solutions.
The ideal candidate will have a strong foundation in machine learning, experience with modern AI architectures (e.g., transformers, diffusion models, or graph neural networks), and a keen interest in applying computational approaches to real-world problems in RNA biology and therapeutic discovery.
Duties and Responsibilities:
Develop innovative machine learning-based drug discovery algorithms and technologies to be applied across Sanford Labs' AI Platform.
Implement AI/ML methodologies, including large language models and generative AI/ML, to address complex challenges in drug discovery.
Monitor and evaluate the performance of AI/ML models and drug discovery solutions.
Utilize software engineering best practices to develop complex AI applications at scale.
Research and stay abreast of emerging technologies relevant to drug discovery and AI/ML.
Proactively scope and deploy novel computational methods and digital technologies.
Education and/or Experience:
Doctorate or master's degree in computer science, mathematics, computational biology, bioinformatics, biomedical data science or a related field.
Expertise in deep learning and machine learning.
Strong experience with Python libraries for data science analysis (e.g., NumPy, Pandas, and Matplotlib) and deep learning (PyTorch or TensorFlow)
Knowledge, Skills, and Abilities:
Ph.D. in computer science, mathematics, computational biology, or bioinformatics, including industry experience.
Deep experience in and theoretical understanding of statistical modeling, machine learning, deep learning, and other relevant quantitative methods.
Familiarity with the latest AI architectures and frameworks, such as Transformer-based models, Graph Neural Networks (GNN), and other generative models including diffusion models, Variational Autoencoders (VAEs), and Generative Adversarial Networks (GANs).
Knowledge of RNA biology, particularly RNA structure, function, and RNA-binding proteins.
Fluency in scientific programming and tool development with Python, R, or equivalents.
Proficiency in C++ or Java is a plus.
Proven record of innovative thinking to propose and champion the development of novel algorithms and AI/ML models that generated interpretable and actionable results for practical applications.
Experience with software development good practices, including code versioning, documentation, and testing.
Experience with cloud computing.
Creative, open-minded, and passionate about scientific research.
Demonstrated ability to thrive in a team environment.
Strong interpersonal, collaborative, organizational, and presentation skills.
Understanding of RNA therapeutic modality discovery and development.
No relocation will be provided for this role; the candidate must be local to the San Diego, CA, region and/or the state of California.
Supervisory Responsibilities:
This position does not currently have direct reports.
Perks and Benefits:
Generous employer-paid healthcare for Medical, Dental, and Vision.
100% Employer Paid Life, STD and LTD
401(k) Employer Match
Generous Vacation and Sick Leave
13 Holidays
Closed over the Christmas and New Year Holiday Break
Associate Scientist
Principal research scientist job in San Diego, CA
Representative responsibilities will include, but not necessarily be limited to, the following:
Collaborate with research, analytical development and process development teams to develop, qualify/validate AAV gene therapy cell-based biological potency assays, protein chemistry assays, and molecular biology assays for process monitoring and drug product release, specifically droplet digital PCR, HPLC, ELISA, culture of primary mammalian cells, and cell based potency assays.
Participate in developing timelines, protocols and reports for assay transfers, qualifications / validations.
Author and review QC analytical SOPs, protocols, and reports as needed
Ensure the timely execution of all routine QC testing, data review, and preparation of summary reports
Perform quality management activities such as deviation, CAPA, change control, investigation of OOS, OOT and anomalous results within the company QMS according to established procedures.
Maintain QC laboratory, track critical reagents and equipment logbooks, and ensure all the equipment is calibrated
Skills:
Seeking a QC Scientist I with broad knowledge and expertise in cell-based potency assays, molecular biology assays, and chemical/biochemical assays as applied to AAV gene therapy products. The QC Scientist will be involved method development and/or method transfer. The QC Scientist will author and execute phase appropriate qualification/validation protocols and reports of QC methods to support product release and stability. The role will perform analysis on characterization, lot release and stability samples for clinical phase AAV Gene Therapy products.
Education:
BS or equivalent in relevant discipline with a minimum of 4 years of relevant industry experience or Master's degree in relevant discipline with a minimum of 1 year of relevant industry experience
Experience in pharmaceutical industry with a GMP testing focus, ideally covering the analytical method and testing lifecycle from development through commercial drug product testing, with experience in a GMP QC release testing role
Experience in an FDA-regulated environment
Entrepreneurial spirit, with strong willingness to take on new challenges required to bring novel medicines to the clinic
Excellent organizational and communication skills
Experience with JMP statistical software a plus.
Late Stage Oncology Clinical Scientist (Director, Non MD) Multiple Positions
Principal research scientist job in San Diego, CA
You will be responsible for scientific oversight, data integrity and quality of clinical trial(s) in support of the development strategy for programs within our Late-Stage Oncology portfolio. **Clinical development expert for assigned studies maintaining current scientific and clinical knowledge in the specific therapeutic and disease area(s) of assignment.
Effectively partner with other clinical and medical colleagues, clinical operations and other functional lines for the successful implementation and execution of the clinical trial(s) within the assigned program.
Responsible for scientific oversight, data integrity and quality of the clinical trial(s).
Represent the study team in governance meetings and submissions, partners with/supports the Development lead/Medical Director regarding study and disease area strategy.
Author protocols, study level informed consent documents, and contributes to authoring of IBs, site training materials, clinical study reports, regulatory responses, and other clinical and regulatory documents; supports preparations for Health Authority meetings, participates as appropriate.
Set the clinical data review strategy and leads the team in the collection of quality data and review of emerging clinical data and trends; reviews and queries data; presents and discusses relevant data to appropriate teams, governance bodies, and other internal and external stakeholders.
In close partnership with medically qualified colleague/s, analyze the emerging safety profile of the drug, keeping the clinical and safety colleagues informed of changes in the safety profile as they occur in the assigned trial(s).
Follow relevant SOPs and regulations, has an excellent understanding of and complies with applicable trainings, seeks opportunities to further improve quality and efficiency of clinical procedures; PhD/Pharm D in a relevant Science discipline and minimum of 5 years Clinical Research experience in industry/CRO, **OR**
MS in a relevant Science discipline and minimum of 7 years of Clinical Research experience in industry/CRO **OR**
BA/BS in a relevant Science discipline and minimum of 10 years Clinical Research experience in a similar role in industry/CRO
Clinical Research experience in the phase 2 - 3/pivotal space in Oncology, ideally on the side of the sponsor and with a track record of successful regulatory submission, inspection, and regulatory approval
Clinical Operations, Safety, Biostatistics, Regulatory, Study Management, Pre-clinical, Pharmacology, Quality Assurance
Experience working on large data sets
Proficiency with Microsoft Office and relevant scientific software
Track record of scientific productivity as evidenced by publications, posters, abstracts and/or presentations
Experience building partnerships across the company to achieve the needs of the program
**Demonstrates passion for helping patients with cancer and for the science of oncology
Flexibility to adapt and navigate through an ever-changing work environment while maintaining integrity and quality in the work assigned
Demonstrates autonomous delivery, problem-solving, and agile decision-making in execution of Clinical responsibilities
Promotes team health and exemplifies Pfizer's leadership behaviors and actionable attitudes
Leverages knowledge and support from others related to overall objectives, strategy, critical issues, and policies
Promotes innovation and takes appropriate risks to challenge the status quo in order to enhance the efficiency of current processes
Embraces evolving technologies and adopts best practices aimed at improving the efficiency and quality of clinical development
Works well in a diverse team environment with colleagues from diverse cultures, backgrounds, and geographies. Work Location Assignment:** This is a hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week
In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.Pfizer compensation structures and benefit packages are aligned based on the location of hire. Relocation assistance may be available based on business needs and/or eligibility.
**Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Medical
Associate Principal / Principal Scientist, Computational Chemistry
Principal research scientist job in San Diego, CA
Neomorph is seeking a highly experienced and strategically minded Associate Principal Scientist or Principal Scientist in Computational Chemistry to join our dynamic and collaborative discovery team. This is a hands-on, individual contributor role - you will lead cutting-edge computational chemistry efforts, roll up your sleeves to generate design hypotheses and deliver actionable insights, while influencing program strategy and scientific direction.
Whether you join as an Associate Principal or Principal level depends on your years of experience and track record. In either case, you will play a key role in advancing our discovery pipeline from target assessment through candidate nomination, partnering with medicinal chemistry, structural biology, biophysics, and biology teams.
Key Responsibilities
Serve as the primary computational chemistry contributor on one or more drug discovery programs - designing, executing and interpreting computational workflows to support hit identification, hit-to-lead, and lead optimization.
Integrate structure- and ligand-based design, cheminformatics, predictive modeling and molecular simulation to propose novel compounds and drive progression of small-molecule therapeutics (including molecular glues/degraders).
Translate SAR, structural and modeling data into innovative design hypotheses; prioritize compounds and support decision-making alongside drug discovery teams.
Collaborate cross-functionally with medicinal chemistry, structural biology, biophysics, and biology to impact program strategy, compound design and project milestones.
Develop, optimize and deploy computational tools, workflows and methods (e.g., docking, MD, free energy calculations, ML/AI-driven design) to enhance our internal capabilities and accelerate discovery.
Present scientific results and strategic recommendations to internal project teams and senior leadership; provide mentorship and scientific guidance to less-experienced colleagues (without direct line-management responsibility).
Stay abreast of emerging computational chemistry technologies, apply deep domain knowledge and help shape the future of our computational capability.
Required Qualifications
Associate Principal Scientist level:
PhD in Computational Chemistry, Theoretical Chemistry, or a related field with 6+ years, MS with 9+ years, or BS with 12+ years of relevant industry experience in drug discovery.
Principal Scientist level:
Ph.D. in Computational Chemistry, Theoretical Chemistry, Chemistry or related field with 8+ years, M.S. with 11+ years or B.S. with 14+ years of relevant industry experience.
For both levels:
Demonstrated hands-on experience in small-molecule drug discovery, with proven ability to apply molecular modeling, docking, free energy calculations, QSAR/ML, and cheminformatics to support compound design and progression.
Strong record of working independently and delivering high-quality scientific work, while also collaborating effectively in cross-functional teams.
Proficiency with commercial and/or open source computational chemistry and molecular modeling software (e.g., Schrödinger, OpenEye, AMBER, GROMACS, etc.), and fluency in scripting/programming (e.g., Python, R).
Excellent communication and collaboration skills, with ability to influence project teams and senior leadership through scientific insight.
Self-starter attitude, willing to roll up sleeves and execute hands-on work while contributing strategically.
Please note: This role is not a people-manager/line-management position - it is a senior individual contributor role, intended for a strong computational scientist who thrives doing the work directly and influencing through scientific leadership rather than managerial oversight.
Base salary range for Associate Principal Scientist is $167,000 ‒ $198,000
Base salary range for the Principal Scientist is: $187,000 - $240,000
Why Neomorph?
At Neomorph, we believe scientific excellence thrives in an environment rooted in transparency, integrity, inclusivity, passion and flexibility. You'll join a growing team at the forefront of targeted protein degradation, where your contributions as an individual contributor will have significant impact on the company's discovery trajectory.
What we offer:
Industry competitive compensation
Annual target bonus
Stock options
401K plan
Career advancement opportunities
Monthly town halls to share business and scientific updates
Work Hard, Stay Well
Comprehensive medical, dental, and vision plans for employees and their dependents
Health and Dependent Care FSA and HSA Plan with monthly Neomorph contribution
Employee Assistance Program
10 holidays + Winter Shutdown + 3 weeks of vacation time with additional accruals after 2nd year of employment, separate sick leave.
Supplemental pay for Pregnancy Disability Leave
Paid Parental Leave for employees with a newborn child or a child placed with them for adoption or foster care
Lifestyle
Casual work environment
Volunteer days off each year to spend time contributing to causes you care about
Flexible work schedule
Access to onsite gym
Onsite space to store your bicycle (or surfboard)
Have Fun!
We believe in work/life balance and Fun is at the core of our Core Values. In addition to department and company happy hours, we have regular company-wide and department lunches and social events (ie Padres games, summer picnic, holiday party, bring your kids to work day).
About Us:
Neomorph is a venture backed biotechnology company solving critical problems in human health through the discovery and development of innovative new medicines against ‘undruggable targets'. Our team is comprised of industry leading experts in protein degradation and molecular glues who have a track record of ground-breaking discoveries in the field. We are committed to leadership in advancing the science and technology of molecular glue drug discovery, while prosecuting a pipeline of projects through clinical development. Our patient-first, science-driven approach is complemented by our dedication to a supportive and collaborative work environment.
Neomorph is headquartered in San Diego, California.
Neomorph is committed to pursuing and hiring a diverse workforce and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of any characteristic protected by applicable federal, state or local law.
Notice to agencies:
Neomorph will not accept unsolicited assistance from recruiting/search agencies for this employment opportunity. Please, no phone calls or emails. All resumes submitted by recruiting or search agencies to any employee at Neomorph via email, the Internet or in any form and/or method without a valid written search/recruitment agreement in place for this position will be deemed the sole property of Neomorph. No fee will be paid in the event the candidate is hired by Neomorph as a result of the referral or through other means.
Research Scientist
Principal research scientist job in Carlsbad, CA
Research Scientist Position: Full time Location: Carlsbad office About Us: NTENT provides a Platform-as-a-Service (PaaS), allowing industry partners to customize, localize and integrate Voice Assistant and Search technologies directly into their business-to-consumer offerings. NTENT utilizes a machine learning algorithmic approach to comprehend massive amounts of information across the web. Through the company's proprietary search engine, ontology and knowledge graph, NTENT makes it easier to decipher meaning, surfacing the most relevant answers, results, content and ads, via conversational interfaces or text.
We are a unique group of brilliant minds intent on discovering, learning and building. We work in a vibrant atmosphere, with an emphasis on personal and professional development. This is an opportunity to tackle complex problems usually reserved for a handful of large companies in the search industry.
About the Opportunity:
We are a dynamic company looking for our next great hire to join our team in Carlsbad, California. We are looking for a Research Scientist to join our team and drive research and development efforts for our News Platform and systems that evaluate the quality of documents and detect misinformation. Duties and Responsibilities:
Partner with product managers, machine learning scientists and engineers to formalize appropriate research questions that are relevant to our News Platform.
Conduct independent research, perform extensive literature reviews, sort through prior published work to find potential solutions.
Design experiments and lead data collection efforts.
Work with large amounts of text data and leverage statistical and machine learning methods.
Communicate and transfer solutions to production together with scientists and engineers.
Communicate ideas, methods, opportunities, and results to cross functional partners.
Skills and Qualifications:
Graduate degree (PhD preferred) in Computer Science, Linguistics, Statistics, Computational Social Sciences or other quantitative field.
3+ years of professional experience or equivalent experience in a research lab. Recent PhD graduates are especially encouraged.
Broad experience on with various applications of NLP (part-of-speech tagging, dependency parsing, entity recognition and extraction etc.)
Broad experience in machine learning and statistical methods, in at least one of the following areas: experimental design, causal inference, machine learning, reinforcement learning, deep learning.
End-to-end experience in research projects, including study design, simulation/testing, data cleaning, data analysis, and reporting.
Proficient with Python or R.
Experience with Spark, PySpark.
Exceptional written, verbal, and visual communication.
The following experience is a plus:
Experience in the news domain (fact checking, detecting misinformation etc.) and knowledge of journalistic principles highly desired.
Experience in computational journalism highly desired.
Publication track record is a big plus!
The ideal candidate will be self-motivated, possess excellent communication skills (both oral and written) and be able to work independently. A keen interest in various aspects of language processing is essential in our multi-disciplinary team. We offer a full comprehensive benefits package including medical, dental and vision. Employees receive a generous time off (PTO) plan and 13 holidays per year. We also offer 401(k) benefits, long term disability benefits and life insurance.
Research Scientist II, High Throughput Chemistry
Principal research scientist job in San Diego, CA
We are seeking a highly skilled and motivated Research Scientist to join our Discovery Chemistry team at Iambic Therapeutics in San Diego, CA. In this role, the ideal candidate will exploit their strong background in organic synthesis, catalysis, and reaction development to design, optimize, and execute high-throughput experiments to drive compound library campaigns. The successful candidate will collaborate cross-functionally with chemistry, biology, compound management, AI/ML, and software teams across the discovery pipeline, leveraging Iambic's HTE platform to accelerate and strengthen our programs.
KEY RESPONSIBILITIES
Design and execute parallel synthetic methods to generate large, high-quality compound libraries.
Identify, develop, and optimize novel synthetic methodologies with a focus on automation compatibility and HTE scalability.
Apply newly developed synthetic routes from traditional bench-scale chemistry to robust, high-throughput, and automated processes.
Oversee the operation, maintenance, and continuous advancement of our chemistry toolkit and automated synthesis equipment.
Analyze research outcomes and library compound data and clearly communicate results and findings to cross-functional project teams.
Ensure all laboratory work is conducted in accordance with established safety protocols and best laboratory and ELN data recording practices.
A strong commitment to teamwork and the ability to function effectively as a core member of an interdisciplinary scientific team (chemistry, biology, software, and automation).
Proactive problem-solving mindset leveraging attention to detail and available resources to identifying bottlenecks, troubleshooting automated processes, and developing solutions to ensure business continuity.
QUALIFICATIONS
Ph.D. degree in Organic Chemistry with 2-5 years of industry experience or Master of Science (MS) degree in Organic Chemistry with 8+ years of industry experience in synthetic organic chemistry.
Strong command of modern organic synthetic methods
Direct hands-on experience with High Throughput Chemistry and/or Parallel Synthesis.
Experience with laboratory automation, liquid handling robotics, and automated analytical and purification systems.
Ability to thrive in fast-paced, highly collaborative, and dynamic research environment.
Excellent written and verbal communication skills; must be able to articulate complex scientific concepts, technical challenges, and results clearly and concisely to diverse audiences.
Proven ability to thrive in a fast-paced, high-volume environment where priorities and synthetic targets may shift rapidly based on biological data.
Strongly Preferred:
Experience with Direct-to-Biology (D2B) strategies for drug discovery.
Familiarity with the principles of medicinal chemistry
Ability to mentor junior scientists
ABOUT IAMBIC THERAPEUTICS
Iambic is a clinical-stage life-science and technology company developing novel medicines using its AI-driven discovery and development platform. Based in San Diego and founded in 2020, Iambic has assembled a world-class team that unites pioneering AI experts and experienced drug hunters. The Iambic platform has demonstrated delivery of new drug candidates to human clinical trials with unprecedented speed and across multiple target classes and mechanisms of action. Iambic is advancing a pipeline of potential best-in-class and first-in-class clinical assets, both internally and in partnership, to address urgent unmet patient need. Learn more about the Iambic team, platform, pipeline, and partnerships at iambic.ai.
MISSION & CORE VALUES
Our mission is to deliver better medicines through innovations in AI-based discovery technologies. The culture and work at Iambic Therapeutics are profoundly strengthened by the diversity of our people and our differences in background, culture, national origin, religion, sexual orientation, and life experiences. We are committed to building an inclusive environment where a diverse group of talented humans work together to discover therapeutics and create technologies.
PAY AND BENEFITS
We offer industry leading competitive pay, company paid healthcare, flexible spending accounts, voluntary life insurance, 401K matching, and uncapped vacation to our team. We are in a brand-new state-of-the art facility in beautiful San Diego with an onsite gym, dining, and easy access to great places to live and play.
Auto-ApplyResearch Scientist
Principal research scientist job in San Diego, CA
1. Design and implement experiments for the formulation and characterization of polymeric, liposomal, lipid and other nanoparticles for in vivo drug delivery.
2. Lead and participate in the assessment and development of early -stage nanoparticle formulation development activities, including targeted therapies.
3. Must have hands -on experience with HPLC, UPLC equipment and methods.
4. Must have hands -on experience with plate -based assays.
5. Must have experience in development of methods to analyze and characterize drug product formulations, components, and functionality.
6. Experience and technical proficiency with HPLC and other methods for analysis and quantification of small molecules, nucleic acids, proteins, lipids, and polymers is preferred.
7. Experience with cell -based assays a plus.
8. Previous experience and technical proficiency in the physical characterization of nanoparticles, including particle sizing is a plus.
9. Familiarity with lab -scale nanoparticle preparation techniques, including microfluidics technology, is a plus.
10. Experience with automated liquid handlers is a plus.
11. Experience with field flow fractionation and multi -angle light scattering a plus.
12. Strong interpersonal, communication, collaboration, and problem -solving skills.
13. Ability to document work and proven record of scientific technical writing
RequirementsDegree in Chemistry, Biochemistry, Pharmaceutical Sciences, Chemical Engineering, Biomedical Engineering, or closely related disciplines. Prefer 0 -1 years+ of relevant experience with PhD, 2 -3 years+ with M.S., and 5 -6 years+ with B.S.
Laboratory: 1 year (Preferred)
HPLC: 1 year (Preferred)
plate -based assays: 1 year (Preferred)
lipid nanoparticle: 1 year (Preferred)
Veterinary Research Scientist
Principal research scientist job in San Diego, CA
Job Description
Job Title: Veterinary Research Scientist
Primary Responsibilities:
This position requires a broad knowledge of the anatomy and physiology of small and large animals to help develop and support in vivo models to screen therapeutics and devices being developed for various disorders. Experience with surgical, dosing and sampling techniques is required. In addition, the Veterinary Scientist is responsible for assisting in the clinical care of animals on surgical studies including post-operative monitoring and evaluations.
Principal Duties and Responsibilities
Perform surgical support and provide anesthesia, surgical, and analgesic technical expertise/advice to facilitate protocol development.
Provide clinical and technical support to internal and external customers, regarding surgical models and services.
Serve as the Research Lead or Study Director responsible for preclinical studies in various species.
Assist in the preparation and review of study protocols and reports.
Provide support for activities of the Institutional Animal Care and Use Committee (IACUC), including protocol review, program review, and facility inspections.
Assist in activities to ensure the facility is in compliance with all applicable regulations, guidelines, and standards that relate to animal care and use. (USDA, FDA, and AALAC)
Train staff on in-vivo procedures
Make recommendations and assist in establishing and enhancing veterinary and animal care standards
Will administer controlled substances and be responsible for maintaining appropriate records.
May develop new or innovative surgical techniques or other procedural improvements appropriate to research studies.
Perform special projects and assist with administrative efforts as needed.
Candidate Requirements:
Background in lab animal (in vivo) research with a focus on surgical techniques is a must.
Ability to perform study duties and responsibilities in multiple species with minimal supervision.
Must be flexible to work various schedules and hours as well as provide comprehensive, after hours, and on-call coverage as needed.
This position requires good communication skills and attention to detail.
Strong work ethic, self-motivation, and the ability to adapt to a dynamic team/work environment are keys to success.
Education:
Degree in veterinary medicine (BVM, DVM, or VMD) preferred.
Graduate-level degree (M.S. or Ph.D.) in pharmaceutical science, life sciences, or pharmacology considered.
Experience:
Minimum 5-7 years of relevant industry experience depending on education level.
Experience working with both small and large animals preferred.
Working knowledge of imaging modalities (TEE, C-arm) will be a plus
A comprehensive understanding of the requirements for GLP study execution and documentation is required.
R&D Scientist
Principal research scientist job in San Diego, CA
Job Description
Our client, a fast-growing leader in the functional food, supplement, and wellness ingredient industry, is seeking an accomplished R&D Scientist to drive innovation and scientific excellence across their ingredient portfolio. This individual will play a critical role in developing, optimizing, and validating ingredient processes and analytical methods to advance the potency, consistency, and bioavailability of natural, bioactive compounds. This position is ideal for a technically driven and entrepreneurial scientist who thrives in a collaborative environment, excels at translating scientific insights into commercial outcomes, and is passionate about functional nutrition and wellness innovation.
The R&D Scientist will lead research and development initiatives focused on ingredient optimization, analytical method development, and bioactive compound testing. Partnering closely with cross-functional teams-including Quality, Mycology, and Operations-this individual will support the full lifecycle of ingredient innovation, from discovery through commercialization. The successful candidate will be hands-on, organized, and capable of managing multiple complex projects simultaneously, while fostering a culture of scientific curiosity, precision, and accountability.
**This is a hybrid position must onsite at least 3 days a week in San Diego, CA.
Key Responsibilities
Develop and optimize analytical and testing methods to support ingredient characterization and functional performance.
Design and validate finished product specifications related to nutritional and bioactive properties.
Partner with external laboratories and contract research organizations to conduct analytical testing and ensure data quality.
Drive new ingredient development projects, including feasibility assessments, process optimization, and product qualification.
Collaborate cross-functionally to ensure projects meet technical, regulatory, and commercial readiness milestones.
Provide scientific input and data to support patent filings and intellectual property development.
Support investigations related to food safety, quality, and testing accuracy in partnership with internal QA/FSQA teams.
Contribute scientific insights and innovative concepts that expand the R&D and innovation pipeline.
Qualifications
Master's degree (M.Sc.) or higher in Chemistry, Biochemistry, Food Science, or a related scientific field.
5+ years of experience in R&D, product development, or analytical science within the functional ingredients, dietary supplement, or food industry.
Experience with analytical methods such as mass spectrometry, chromatography, DNA sequencing, or immunoassays is strongly preferred.
Proven experience collaborating with external laboratories or CROs.
Strong technical writing, data interpretation, and presentation skills.
Ability to manage multiple complex projects in a fast-paced, dynamic environment.
Creative, detail-oriented, and motivated by scientific discovery and product excellence.
This is an exciting opportunity to join a mission-driven organization at the forefront of functional ingredient innovation-combining science, sustainability, and wellness to shape the next generation of food and nutrition solutions. If you are an experienced R&D scientist seeking to make a meaningful impact in a rapidly growing segment of the health and wellness industry, we'd love to connect with you.
Compensation: $120,000 - $140,000plus benefits
If this sounds like the position you have been waiting for, please apply using the online application or the link below - all inquiries are strictly confidential. Our focus is to assist you to make your best next career move, and we will not use your information for any other purpose.
Kalon Search is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.
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R&D Scientist
Principal research scientist job in Carlsbad, CA
R&D Scientist - NGS Technology and Applications
title depends on qualification and experience)
Universal Sequencing Technology (UST) Corporation (universalsequencing.com), a leading NGS technology company engaged in long range/long read sequencing technology and single cell sequencing technology development, headquartered in greater Boston with a branch in San Diego, is looking for an outstanding R&D scientist to join our NGS technology and product development team in San Diego. This position is a unique opportunity to work on a cutting edge NGS library technology which enables many previously unachievable applications, especially in the clinical space.
This person will work closely with a team of molecular biologists, bioinformatics scientists, instrument engineers and manufacturing specialists to develop a revolutionary single cell sequencing technology. He/she will play a key role in the development and validation of the technology as well as the commercial launch of products. He/she will also interact with external collaborators and early access customers, and provide technical support.
The ideal candidate should have extensive cellular and molecular biology experience. He/she must have direct experience on cellular assay development and RNA manipulation; strong project management skills; ability to take initiative; effective verbal and written communication skills; and be an excellent team player. RNA-Seq, NGS library preparation, and sequencing data analysis skill under both Linux and Windows environment are desired; Molecular biology reagent kit development experience is a plus.
Key Responsibilities:
Lead NGS based single cell sequencing assay and reagent kit development
Establish product quality control assays for in-process & final product test and deliver well-characterized & robust processes to manufacture
Design and execute experiments, and analyze data independently
Support current product improvement and commercialization
Interact with collaborators and customers to promote UST technology and product
Qualifications:
Ph.D. in molecular biology, cellular biology, biochemistry or related fields (M.Sc. with exceptional experience will be considered)
Minimum 3-years of cellular assay development and gene expression profiling experience
Single cell sequencing library preparation, immune repertoire sequencing or early tumor detection experience is a plus
Product development experience is preferred
Auto-ApplyGas Chromatography Product Development Scientist
Principal research scientist job in San Diego, CA
**Be visionary** Teledyne Technologies Incorporated provides enabling technologies for industrial growth markets that require advanced technology and high reliability. These markets include aerospace and defense, factory automation, air and water quality environmental monitoring, electronics design and development, oceanographic research, deepwater oil and gas exploration and production, medical imaging and pharmaceutical research.
We are looking for individuals who thrive on making an impact and want the excitement of being on a team that wins.
**Job Description**
**Job Summary:**
TAPI is seeking a highly experienced Scientist, with a proven record of developing Gas Chromatography Instrumentation, to join our Research and Development team. This role will focus on the development of new GC-based instrumentation to support innovation in analytical chemistry and production workflows. The ideal candidate will bring deep expertise in gas chromatography, method development, and instrumentation, along with a strong background in production or R&D environments.
**Key Responsibilities**
+ Lead the design and development of advanced gas chromatography (GC) methods and instrumentation.
+ Operate, maintain, and troubleshoot GC instruments including FID, DBD, FPD, and PID detectors.
+ Collaborate with cross-functional teams to support product development and quality assurance.
+ Perform sample preparation, calibration, and quantitative analysis with high precision.
+ Document and validate analytical methods in compliance with internal and regulatory standards.
+ Mentor junior technicians and contribute to technical training initiatives.
+ Communicate findings clearly through technical reports and presentations.
**Minimum Qualifications**
Education: Bachelor of Science (B.Sc.) in Chemistry, Biochemistry, Analytical Chemistry, or a related scientific field.
Experience: Minimum of 10 years of relevant work experience in a R&D or Manufacturing environment.
Technical Expertise:
- Proficiency in GC method development, validation, and troubleshooting.
- Proven experience with GC instruments including FID, DBD, FPD, and PID.
- Familiarity with chromatography data systems such as Chromperfect .
- Strong understanding of sample preparation, calibration, and quantitative analysis.
Soft Skills:
- Exceptional analytical thinking and attention to detail.
- Excellent written and verbal communication skills.
**Preferred Qualifications**
+ Experience in developing GC technologies for novel applications.
+ Knowledge of regulatory standards and documentation practices (e.g., cGMP, SOPs).
+ Ability to work independently and manage multiple projects simultaneously.
**Why Join TAPI?**
At TAPI, you'll be part of a dynamic team driving innovation in analytical science. We offer competitive compensation, a collaborative work environment, and opportunities for professional growth.
**Salary Range:**
$113,600.00-$151,400.000
**Pay Transparency**
The anticipated salary range listed for this role is only an estimate. Actual compensation for successful candidates is carefully determined based on several factors including, but not limited to, location, education/training, work experience, key skills, and type of position.
Teledyne conducts background checks on qualified applicants who receive a conditional offer of employment in accordance with applicable laws, regulations and ordinances. Background checks may include, but are not limited to, education verification, employment history and verification, criminal convictions, Motor Vehicle Report (MVR & driving history), reference check, credit checks/credit history and drug testing. All qualified applicants with arrest or conviction records will be considered for employment in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.
Teledyne and all of our employees are committed to conducting business with the highest ethical standards. We require all employees to comply with all applicable laws, regulations, rules and regulatory orders. Our reputation for honesty, integrity and high ethics is as important to us as our reputation for making innovative sensing solutions.
Teledyne is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status, age, or any other characteristic or non-merit based factor made unlawful by federal, state, or local laws.
You may not realize it, but Teledyne enables many of the products and services you use every day **.**
Teledyne provides enabling technologies to sense, transmit and analyze information for industrial growth markets, including aerospace and defense, factory automation, air and water quality environmental monitoring, electronics design and development, oceanographic research, energy, medical imaging and pharmaceutical research.
Scientist
Principal research scientist job in San Diego, CA
Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost.
Job Description
• The candidate will be a key member of the Ion Channel/GPCR/Transporter Pharmacology group, and provide experimental support for programs from target nomination through declaration of a clinical candidate. S/he will assist with the characterization of Client membrane targets, MoA studies and the development of HTS assays.
• A MS degree with a minimum of 3 - 5 years of experience or a BS degree with a minimum of 4 - 8 years of laboratory experience is required. Hands- on expertise with plate-based assays, molecular biology, biochemistry, binding assays and cell culture techniques is essential. Working knowledge of ion channel, transporter or GPCR pharmacology is preferred. This position will be located in La Jolla, CA and may require up to 10% travel.
Additional Information
Best Regards,
Anuj Mehta
**************
Morristown, NJ 07960
Associate Scientist - Assay Development
Principal research scientist job in Vista, CA
How you will contribute:
We are seeking a passionate and mission-driven Associate Scientist - Assay Development with passion for development, execution, and continuous improvement of the most critical assays and experimental methods in our drive towards producing the highest quality functional plant protein with exceptional yield and quality. This individual will lead efforts in our strain, nutrient, and environmental screens to optimize growth, protein production, and extraction while aiding in standardization of scale-down assay throughput & quality with fellow Scientists and Engineers. The individual will have the opportunity to make an immediate and sustainable impact in the development of the company.
What you will be working on:
Streamline assay development and assay throughput for key R&D projects related to plant strain screening, protein purification & extraction, odor and flavor modification, and protein functionality testing.
Drive operational efficiency, precision, and scientific rigor to streamline bottlenecks in current experimental methods with a move towards standardization of methods and improved experimental outcomes.
Leverage statistics and statistical design of experiments (DoE) to identify single and multi-factor variables that drive key metrics of interest as it relates to plant growth rate, protein production, protein extraction efficiency, and functional properties related to functionality, flavor, odor and color.
Develop new and innovative experimental and scale-down assays to mimic plant growth and downstream processing.
Implement improved analytical methods (chromatography, spectroscopy, etc.) to assess the effectiveness and robustness of extraction processes. Leverage these insights and in-process data to troubleshoot current processes and provide insights for the development of future research.
What you bring to Plantible:
B.S. or M.S in Biochemistry, Chemistry, Chemical Engineering or Bioengineering.
3 to 5+ years of industry experience in assay development in an industrial environment.
Excellent laboratory skills and a passion for impacting R&D outcomes through experimentation where solid data is the ultimate influencer.
Assay development experience in a diversity of applications where method improvement and standardization drove improved efficiency and outcomes.
A willingness to solve problems using a combination of clever scientific approaches, rigorous and coordinated execution, and a bias to action.
Relevant experience with screening photosynthetic organisms and/or protein production in varied organisms is preferred.
Ability to learn quickly, solve complex problems and have excellent data analysis/interpretation skills.
Excellent verbal and written communication and presentation skills.
Being a self-starter and able to respond creatively and simply to continuous change and steady growth environment.
Thrive in a fast-paced environment where the primary focus is on simplification and optimization.
Choose Plantible Foods
Joining Plantible means contributing to a sustainable future for all. We are a venture backed startup that is both spreading happiness amongst our employees and to current and future generations. We believe diversity creates uniqueness. Our team is composed of highly talented people with different interests and hobbies, which makes for a rich working environment.
At Plantible we are continually working on our offerings to foster the best team. Check it out!
Competitive health and wellness benefits
Medical, Dental and Vision Insurance
Discretionary Unlimited PTO Program
Paid Holidays
401k Program
Career Stipend
Career development and growth opportunities
Working in a rapidly growing, flexible and entrepreneurial environment
Team building and company-wide events
Financial support with your relocation, if necessary, ensuring a smooth transition
Plantible Foods is an equal employment opportunity employer. Candidates are considered for employment without regard to race, creed, color, national origin, age, sex, religion, ancestry, veteran status, marital status, gender identity, sexual orientation, national origin, liability for military service, or any other characteristic protected by applicable federal, state, or local law. If you are interested in learning the status of your application, please note you will be contacted directly by the appropriate human resources contact person if you are selected for further consideration. Plantible Foods reserves the right to defer or close a vacancy at any time.
If you feel your skill set does not meet all listed qualifications for the role, we still encourage you to apply. As we continue to grow our company, we are seeking a range of candidates and would gladly consider you for other current or upcoming roles that may be a fit!
Associate Scientist I, Discovery Chemistry (Bioconjugation)
Principal research scientist job in San Diego, CA
Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing.
Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.
Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.
The Position
Arrowhead is seeking a highly motivated Associate Scientist to join our growing Discovery Chemistry team at our San Diego site. This individual will primarily focus on oligonucleotide bioconjugation, peptide synthesis, purification, and analytical chemistry. As a discovery chemist, you will play a key role in the development and optimization of si RNA-based therapeutics by applying your expertise in bioconjugation strategies and peptide chemistry.
Responsibilities
Maintain a well-documented laboratory notebook
Track progress against project timelines, generate regular status updates, and communicate progress and issues to management
Perform tasks across projects
Manage time effectively to meet deadlines
Adhere to safe laboratory practices
Prioritize and perform synthesis, purification, and analysis of conjugates based on project deliverable timelines
Requirements:
B.S. or M.S. Chemistry or Biochemistry degree with excellent understanding of organic and analytical chemistry
0-3 years of experience working in a chemistry laboratory
Experience with a wide range of analytical techniques, especially HPLC
Ability to quickly learn new procedures and techniques
Preferred:
Experience working with large-molecule synthetic targets, particularly oligonucleotides, in an academic or industry setting
Experience with solid-phase peptide synthesis (automated and/or manual)
Prior experience in a pharmaceutical or biotechnology environment
California pay range $60,000-$80,000 USD
Arrowhead provides competitive salaries and an excellent benefit package.
All applicants must have authorization to work in the US for a company.
California Applicant Privacy Policy
Auto-ApplyScientist I
Principal research scientist job in San Diego, CA
Qualifications: • General knowledge of Biology, Immunology, Flow Cytometry or other related discipline. • Familiarity with operation of routine laboratory instruments. • Effective oral and written communication skills. • Effective interpersonal skills. • Effective analytical and problem solving skills. • Demonstrated ability to to follow established policies and procedures. • Demonstrated ability to interpret and present data of simple to moderate complexity. • Demonstrated ability to keep accurate and complete laboratory records and logs. • Previous experience with Flow Cytometry and related software is a plus. Education and Experience: • Minimum Bachelor's degree in a biological science discipline • Minimum 0-2 years of relevant experience
Responsibilities:
The Scientist I is responsible for assisting in the development and evaluation of new reagents and enhancements to existing reagents. Executes experiments independently and evaluates and discusses data. Presents and explains material of simple to moderate complexity and prepares protocols and other documents. Has job skill and technical knowledge to perform established procedures. Under general supervision, plans, designs and performs reagent development activities. Work focus includes areas of Immunology, Cell Biology and Stem Cells using techniques such as multi-parameter flow cytometery, cell stimulation and cell culture assays. Direction is defined jointly with supervisor to meet short and mid-term goals. This position will regularly work with human and laboratory animal tissues. Primary duties include the following: • Performs experiments to evaluate new reagents using flow cytometer.. • Prepares protocols, reports and summaries. • Tabulates and analyzes experimental dat
Qualifications
Minimum Bachelor's degree in a biological science discipline
Additional Information
College degree or HS Diploma with +5 years biopharmaceutical industry experience
Associate Research Scientist
Principal research scientist job in San Diego, CA
• Performance of development, validation, and sample analysis assays, for drugs and antibodies to drugs, from biological samples, for projects according to prescribed procedures and practices as well as project directives.
• Perform ELISA's and Meso Scale methods for PK, biomarker, immunogenicity and other assessments in matrix.
• Basic knowledge of ELISA and Immunogenicity assay methodologies.
• Basic understanding of statistics and laboratory calculations
• Basic understanding of GLP guidelines
• Attention to detail and proficient in documentation
• Excellent communication skills
• Requirements: Minimum of Bachelor degree in a Sciences major plus relevant experience
Qualifications
Far acuity-ability to see clearly at 20 feet or more; near acuity-ability to see clearly at 20 inches or less; depth perception-ability to judge distance and space relationships; color vision-ability to distinguish and identify different colors.
BS preferred w/2-3 years of experience. Will consider candidate with AS if has strong GLP experience
Additional Information
negotiable 1st shift hrs. FT hrs.
$17+ an hour
Oncology Late Stage Clinical Scientist (Senior Manager, Non MD)
Principal research scientist job in San Diego, CA
You will be responsible for scientific oversight, data integrity and quality of clinical trial(s) in support of the development strategy for programs within the Late-Stage Oncology portfolio. KEY RESPONSIBILITIES Clinical development expert for assigned studies maintaining current scientific and clinical knowledge in the specific therapeutic and disease area(s) of assignment. Effectively partner with other clinical and medical colleagues, clinical operations and other functional lines for the successful implementation and execution of the clinical trial(s) within the assigned program. Responsible for scientific oversight, data integrity and quality of the clinical trial(s). Represent the study team in governance meetings and submissions, partners with/supports the Development lead/Medical Director regarding study and disease area strategy. Author protocols, study level informed consent documents, and contributes to authoring of IBs, site training materials, clinical study reports, regulatory responses, and other clinical and regulatory documents; supports preparations for Health Authority meetings, participates as appropriate . Set the clinical data review strategy and leads the team in the collection of quality data and review of emerging clinical data and trends; reviews and queries data; presents and discusses relevant data to appropriate teams , governance bodies, and other internal and external stakeholders. In close partnership with medically qualified colleague/s , analyze the emerging safety profile of the drug, keeping the clinical and safety colleagues informed of changes in the safety profile as they occur in the assigned trial(s). Follow relevant SOPs and regulations, has an excellent understanding of and complies with applicable trainings , seeks opportunities to further improve quality and efficiency of clinical procedures; MINIMUM QUALIFICATIONS PhD/Pharm D in a relevant Science discipline and minimum of 2 years Clinical Research experience in industry/CRO, OR MS in a relevant Science discipline and minimum of 5 years of Clinical Research experience in industry/CRO OR BA/BS in a relevant Science discipline and minimum of 7 years Clinical Research experience in a similar role in industry/CRO Clinical Research experience in the phase 3/pivotal space in Oncology, ideally on the side of the sponsor and with a track record of successful regulatory submission, inspection, and regulatory approval. Clinical Operations, Safety, Biostatistics, Regulatory, Study Management, Pre-clinical, Pharmacology, Quality Assurance. Experience working on large data sets. Proficiency with Microsoft Office and relevant scientific software Effective communication, presentation, and organizational skills to ensure coordinated and timely delivery. Track record of scientific productivity as evidenced by publications, posters, abstracts and/or presentations. Experience building partnerships across the company to achieve the needs of the program. PREFERRED QUALIFICATIONS Experience in Hematology Oncology COMPETENCIES FOR SUCCESS Demonstrates passion for helping patients with cancer and for the science of oncology. Flexibility to adapt and navigate through an ever-changing work environment while maintaining integrity and quality in the work assigned. Demonstrates autonomous delivery, problem-solving, and agile decision-making in execution of Clinical responsibilities. Promotes team health and exemplifies Pfizer's leadership behaviors and actionable attitudes. Leverages knowledge and support from others related to overall objectives , strategy, critical issues, and policies. Demonstrates foresight and judgment to make complex decisions Promotes innovation and takes appropriate risks to challenge the status quo in order to enhance the efficiency of current processes. Embraces evolving technologies and adopts best practices aimed at improving the efficiency and quality of clinical development Has a global perspective and mindset. Works well in a diverse team environment with colleagues from diverse cultures, backgrounds, and geographies . Work Location Assignment: This is a Hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.Pfizer compensation structures and benefit packages are aligned based on the location of hire. Relocation assistance may be available based on business needs and/or eligibility. Sunshine Act Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. EEO & Employment Eligibility Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Medical
Ocular Research Scientist
Principal research scientist job in San Diego, CA
We are seeking to find an accomplished Ocular Scientist with requirements of a broad knowledge of Ocular anatomy, physiology, and biochemistry to help develop and support in vivo models to screen small molecule, cell/gene therapy, as well as large molecule therapeutics and devices being developed for various ocular disorders.
Experience with ocular surgical, dosing and sampling techniques is necessary. The Ocular Research Scientist will assist in the development of protocols and criteria to effectively and efficiently carry out experiments.
The successful candidate will provide investigators with written and oral updates to scientific data generated during the conduct of the studies they oversee.
They may also participate in presentations at scientific meetings and/or preparation of manuscripts for presentations. Expertise to guide investigators on the approaches necessary to characterize the pharmacological effects of target molecules based on disease mechanisms is valuable.
Principal Duties and Responsibilities:
The Scientist will perform the following duties and responsibilities:
Assume the functional role of Principal Investigator or Study Director for preclinical ophthalmic studies.
Participate in study design and the development and generation of study protocols.
Manage the conduct of preclinical studies, evaluated the data, and assist in the writing and review of final reports.
Develop and execute research studies to expand research capabilities.
Develop and execute training programs for research associates and junior team members.
Write or revise Standard Operating Procedures (SOPs) to assure facility compliance with applicable regulations, client expectations, and current industry standards.
May be asked to serve on the Institutional Animal Care and Use Committee (IACUC)
Requirements:
Hands-on in vivo experience with multiple research species, at a minimum, rodent, and rabbit.
Ability to perform ocular injections, such as sub-conjunctival, sub-tendon, retrobulbar, intravitreal, and/or subretinal injections.
Experience with various imaging modalities, such as Optical coherence tomography (OCT), fundus photography, and fluorescein angiography.
Experience with other ocular techniques, such as intraocular pressure measurements, electroretinography (ERG), or optokinetic response (OKR).
Ability to perform duties and responsibilities with minimal supervision
Ability to understand Standard Operating Procedures (SOPs) and study protocols.
Must be flexible to work various schedules and hours as well as provide comprehensive, after-hours, and on-call coverage as needed.
Education
Graduate-level degree (M.S./ PhD/ DVM, VMD) required. Post Doctoral candidates are preferred.
Additional training in the GLPs and other applicable regulations required.
Experience
Minimum 3-6 years of experience required, based on education.
scientist- II
Principal research scientist job in San Diego, CA
Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost.
Job Description
• The new Lead Discovery team is a critical part of the Discovery Sciences (DS) organization in Janssen R&D, and is committed to the delivery of high quality chemical leads needed for the generation of small molecule clinical compounds in all five Janssen Therapeutic Area (TA) discovery teams.
• This mission requires deep scientific expertise in a number of disciplines including chemistry, cellular and molecular pharmacology, and screening technologies coupled with an ability to work collaboratively with internal and external partners. Building on a strong legacy of success, we are currently seeking an outstanding individual to join our team as an Associate Scientist.
• The candidate will be a key member of the Ion Channel/GPCR/Transporter Pharmacology group, and provide experimental support for programs from target nomination through declaration of a clinical candidate. S/he will assist with the characterization of Client membrane targets, MoA studies and the development of HTS assays.
• A MS degree with a minimum of 3 - 5 years of experience or a BS degree with a minimum of 4 - 8 years of laboratory experience is required.
• Hands- on expertise with plate-based assays, molecular biology, biochemistry, binding assays and cell culture techniques is essential.
• Working knowledge of ion channel, transporter or GPCR pharmacology is preferred. This position will be located in La Jolla, CA and may require up to 10% travel.
Qualifications
A MS degree with a minimum of 3 - 5 years of experience or a BS degree with a minimum of 4 - 8 years of laboratory experience is required.
• Hands- on expertise with plate-based assays, molecular biology, biochemistry, binding assays and cell culture techniques is essential.
Additional Information
Sneha Shrivastava
Technical Recruiter (Clinical/Scientific)
Artech Information Systems LLC
360 Mt. Kemble Avenue, Suite 2000 | Morristown, NJ 07960
Office: ************ | Fax: ************
Connect with us on - LinkedIn | Facebook | Twitter
Scientist I
Principal research scientist job in San Diego, CA
Qualifications:
• General knowledge of Biology, Immunology, Flow Cytometry or other related discipline. • Familiarity with operation of routine laboratory instruments. • Effective oral and written communication skills. • Effective interpersonal skills. • Effective analytical and problem solving skills. • Demonstrated ability to to follow established policies and procedures. • Demonstrated ability to interpret and present data of simple to moderate complexity. • Demonstrated ability to keep accurate and complete laboratory records and logs. • Previous experience with Flow Cytometry and related software is a plus. Education and Experience: • Minimum Bachelor's degree in a biological science discipline • Minimum 0-2 years of relevant experience
Responsibilities:
The Scientist I is responsible for assisting in the development and evaluation of new reagents and enhancements to existing reagents. Executes experiments independently and evaluates and discusses data. Presents and explains material of simple to moderate complexity and prepares protocols and other documents. Has job skill and technical knowledge to perform established procedures. Under general supervision, plans, designs and performs reagent development activities. Work focus includes areas of Immunology, Cell Biology and Stem Cells using techniques such as multi-parameter flow cytometery, cell stimulation and cell culture assays. Direction is defined jointly with supervisor to meet short and mid-term goals. This position will regularly work with human and laboratory animal tissues. Primary duties include the following: • Performs experiments to evaluate new reagents using flow cytometer.. • Prepares protocols, reports and summaries. • Tabulates and analyzes experimental dat
Qualifications
Minimum Bachelor's degree in a biological science discipline
Additional Information
College degree or HS Diploma with +5 years biopharmaceutical industry experience