Principal research scientist jobs in Santa Cruz, CA

Join a Leading Applied Research Lab Pushing the Boundaries of Reinforcement Learning Are you passionate about advancing the frontiers of reinforcement learning (RL)? An innovative AI research lab is seeking talented and ambitious scientists to shape the next generation of RL techniques-especially where they intersect with large models and environment generation. About the Role As an AI Research Scientist focused on RL, you will: Develop novel optimization-based methods for automated RL environment generation Establish baselines for evaluating the quality and diversity of RL environments Design infrastructure to create dynamic environments from historical datasets and agent evaluations Drive your own research agenda, contributing directly to the progress of our platform and the broader AI community What We're Looking For PhD (or equivalent experience) in machine learning, computer science or a related field Strong publication record and/or evidence of research impact (open source, deployed systems, etc.) Deep expertise in reinforcement learning and machine learning fundamentals Proficient in Python and at least one modern ML framework (such as PyTorch or JAX) Bonus Points Experience with post-training large language models (LLMs) Demonstrated software engineering skills Ability to communicate research findings effectively to both technical and non-technical audiences

About the Company We are a seed-stage AI company building the industry standard for evaluating and benchmarking large language models on real enterprise tasks. About the Role As a Research Scientist, you will develop new benchmarks, methodologies, and evaluation pipelines that shape how cutting-edge models are assessed, compared, and deployed in production environments. Your work will directly influence model selection and safety decisions across foundation model labs, high-growth AI product companies, and Fortune-scale enterprises. Responsibilities Benchmarking & Model Analysis Evaluate newly released models as they launch (e.g., Gemini, DeepSeek, etc.) Run large-scale assessment workflows using internal evaluation infrastructure Compare model performance across enterprise-grade task categories Design New Benchmarks from Scratch Identify high-value model application domains through research exploration Construct datasets, including labeling strategy and workforce coordination Write short “white-paper-style” summaries explaining benchmark purpose, method, and findings Advance Automated Evaluation Methodologies Improve systems for scoring generated text beyond standard metrics Explore research in reference-free, rubric-based, and human-aligned evaluation Develop new techniques for reliability, consistency, and repeatability Cross-functional Collaboration Work closely with engineering to scale evaluation infra Partner with customers to refine evaluation relevance and task fit Influence product direction through research insights Qualifications 0-3 years post-grad experience (Master's, PhD, or equivalent applied research) Publications, preprints, or demos showing cutting-edge work Experience with diffusion models, NLP, multimodal, or benchmarking work Ability to operate independently with ambiguity Clean, maintainable research codebases Candidates from: top engineering/research universities applied AI startups well-regarded research internships Required Skills Built or contributed to a benchmark or evaluation methodology Experience in enterprise task model evaluation Stanford / top lab adjacency (per their historical hiring success) Preferred Skills Wants to publish as primary motivation Purely academic with slow timelines Big-tech culture fit concerns (Meta / Google / Salesforce specifically noted-but case-by-case) Pay range and compensation package Base Salary: up to $250K depending on background Equity: typically 0.3% - 0.5%, flexibility for exceptional candidates Rapid equity refresh possible based on impact Equal Opportunity Statement Visa sponsorship available. Relocation support. Health & dental coverage. Lunch + dinner provided, snacks & coffee. Unlimited PTO. Weekly happy hours with community guests. Team events (bowling, hiking, rock climbing, etc.). Swag program (hats, etc.). Work Environment & Culture In-person, San Francisco HQ (required). Core hours: 9-5, some teammates extend voluntarily. Most team members work 1 weekend day per week (flexible). High-ownership, low-ego, collaborative. Live demos Mondays, team lunch Thursdays, community Fridays. Early-stage pace, applied focus-not academic publishing. Tech Environment (while research-focused, exposure beneficial) Backend: Python / Django. Frontend: React + TypeScript. Infra: AWS. Evaluation frameworks + internal tooling. Why This Role Is Unique The company already collaborates with foundation model labs, high-growth AI vertical product companies, and Fortune 500 enterprises (not publicly facing). ChatGPT Vals AI $5M seed raised, runway of 2+ years at current burn. Only one research scientist is being hired-true founding impact. Opportunity to define industry standards for model trust, reliability, and certification. Positioned to become the rating agency for generative AI.

Job Title: Research scientist (Robotics, AI) Position Type: Full-Time / Permanent Salary range: $200,000/yr - $270,000/yr Job Description: We are an early-stage robotics startup working on building multi-purpose mobile robots that can do complex manipulation tasks. We are looking for a creative, skilled, and motivated research scientists to join our founding team in advancing robot manipulation capabilities. We are looking for people with proven expertise in machine learning and/or robotics. You will collaborate with a team of talented researchers and engineers, and drive ongoing innovation and technological advancements within the company. This is a full-time on-site role in Santa Clara, CA. Responsibilities: Develop new algorithms and methods for training AI models for enhancing the robot dexterity. Conduct cutting edge research across multiple disciplines (Robotics, RL/IL, control, perception, LLM, VLM, etc.). Work with large-scale ML systems and large-scale model training/fine-tuning. Design and implement state-of-the-art learning-based manipulation/navigation/control algorithms on real robots. Work with other teams to develop a diverse set of robust manipulation skills for robots. Requirements: Ph.D. degree in Robotics, Computer Science/Engineering, Electrical Engineering, Mechanical Engineering, etc., or equivalent research experience. Passionate about working with robots and building robot products. Excellent analytical, problem-solving, and communication skills. At least 3 years of experience conducting independent research. Deep understanding of the SOTA robot learning techniques (reinforcement learning, imitation learning, etc.) A track record of research excellence with your work published in top conferences and journals such as Science Robotics, IJRR, RSS, CoRL, ICRA, NeurIPS, ICML, ICLR, CVPR, etc. Proficient with Python. Proficient with deep learning libraries such as PyTorch/TensorFlow/Jax. Experience with real robot experiments. Experienced with robot simulators such as Isaac Gym/ Isaac Sim/ SAPIEN/ MuJoCo/Drake, etc. About Us: Founded in 2009, IntelliPro stands as a global leader in talent acquisition and HR solutions. Our commitment to delivering unparalleled service to clients, fostering employee growth, and building enduring partnerships sets us apart. With a dynamic presence in the USA, China, Canada, Singapore, Philippines, UK, India, Netherlands, and Germany, we continue to lead the way in global talent solutions. IntelliPro is proud to be an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. We also ensure that all applicants have access to accommodations throughout the hiring process. Learn more at *************************** Compensation: The compensation offered will depend on various factors, including location, experience, education, and job-related skills. This role includes a competitive base salary, bonus, equity, and a comprehensive benefits package, subject to eligibility.

We're working with a San Francisco client that's got a research team of 50~ professionals and looking to further expand it. They are specifically looking to flesh out their Research Group by hiring a Research Scientist on a hybrid basis. They have seen $300M in a recent fund raise. Skills targeted: PhD in Physics/ Quantum Physics/ Theory/ Statistics/ Mathematics/ Computational Science or similarly related field. 2+ YoE working with AI Agents. Good exposure to LLMs. Ideally a background in Audio focused research. Alternatively Search, would also be highly advantageous. TC package of $1-1,5M with sizeable base salary & equity package. If that looks of interest, apply & Goliath will be in touch!

Veteran-Owned Firm Seeking DSP Communications Research Scientist with TS/SSBI/SCI for a Role in Monterey, CA My name is Stephen Hrutka. I lead a Veteran-Owned management consulting firm in Washington, DC. We specialize in Technical and Cleared Recruiting for the Department of Defense (DoD), the Intelligence Community (IC), and other advanced defense agencies. At HRUCKUS, we support fellow Veteran-Owned businesses by helping them recruit for positions across organizations such as the VA, SBA, HHS, DARPA, and other leading-edge R&D-focused defense agencies. We seek to fill a DSP Communications Research Scientist role in Monterey, CA. The ideal candidate should possess a TS/SSBI/SCI clearance, hold an M.S. in a relevant field (Ph.D. preferred), and have at least 2 years of professional experience, with 5 years being highly desirable. If you're interested, I'll gladly provide more details about the role and discuss your qualifications further. Thanks, Stephen M Hrutka Principal Consultant HRUCKUS LLC Executive Summary: HRUCKUS seeks a DSP Communications Research Scientist with TS/SSBI/SCI for a role in Monterey, CA. Position Description: We seek a highly qualified research engineer/scientist to solve challenging technical problems in signal processing that are critical to national security. Our client has a national reputation for delivering uniquely capable solutions to very challenging problems and a long track record of consistent innovation and success against the most difficult issues faced by their customers. These problems typically involve processing of signals in very stressful RF conditions, including low signal-to-noise ratio, high levels of interference, and non-stationary environments. Position Duties: Research, design, and implement advanced signal processing algorithms in software for various RF applications. Work as an individual principal investigator or part of a small team of engineers. Perform RF signal and data analysis, reverse engineering, simulation, and modeling. Implement new algorithms in C/C++ and Python. Support transition of algorithms to real-time, high-performance production computing environments. Communicate effectively, verbally and in writing, on complex technical subjects to customers, end-users, and partners at varying levels appropriate to each audience. Translate customer objectives to technical requirements, manage performance and schedule expectations, and communicate project status and technical performance evaluations. Required Expertise and Experience: An outstanding background in signal processing, digital communications, detection and estimation theory, remote sensing, radar signal processing, adaptive antenna array processing, or navigation/geolocation. Demonstrated programming skills and experience in scientific programming are required. The ideal candidate has experience implementing signal processing algorithms in C/C++ and Python. The successful applicant will have extensive expertise and experience in one or more of the following fields: Signal processing Digital communications Detection and estimation theory Remote sensing Radar signal processing Adaptive antenna array processing Navigation/geolocation Desired Qualifications: Some experience with Linux and open-source tool chains is desirable. Experience with software-defined radio (SDR), baseband architecture, RF architecture, and/or wireless propagation and modeling is desirable. Experience with modern communications protocols, including LTE, WCDMA, GSM, 802.11, or 802.16, is desirable. Knowledge of numerical linear algebra is a plus. Good customer communication and presentation skills (written and verbal) are essential. Required Education and Experience: An M.S. in a related field is required, and a Ph.D. is desirable. U.S. Citizenship is required with an in-scope Top Secret/SSBI. A minimum of two years of work experience is required; five or more years is desirable. Details: Job Title: DSP Communications Research Scientist. Locations: Monterey, CA. FULL RELOCATION PAID. Security Clearance Requirement: TS/SSBI/SCI. Assignment Type: Full-time. Salary Range: $126,000 to $174,000 per year.

AI/ML Scientist - Build the Future of Physics AI- $250,000 to $275,000 Salary You will be part researcher, part builder, part pioneer, someone who thrives at the intersection of machine learning and physics based simulation. The platform is built on massively scalable, cloud native simulation technology that makes it possible to run thousands of high fidelity simulations quickly and easily. This foundation unlocks something big, enabling the generation of large scale datasets that power the next generation of ML models across industries. You will be on the front lines of building and productizing new machine learning approaches for physics based problems, from CFD to thermal simulation. Your work will not just live in a paper, it will deliver measurable value to customers, shape new product capabilities, and push the boundaries of what is possible in Physics AI. You know that rush when your work goes from experiment to production, when the models perform, the results hold up, and you can see the impact firsthand? That is what this role is about. Ready to shape the future of Physics AI? Let's talk. No up to date resume required.

located in San Francisco, CA Responsibilities of the Scientist/Sr. Scientist-Stem Cell Biology/Embryology: Design and execute experiments in stem cell differentiation, organoid generation, and tissue engineering. Innovate then execute experiments to generate and differentiate human stem cells, develop functional assays, assess and interpret experimental workflows Perform mammalian embryo dissections, tissue isolations, and culture experiments to study and model developmental processes. Apply principles of developmental biology and embryology to guide tissue maturation and patterning. Collaborate with biomaterials and engineering teams to integrate cells and tissues. Develop and optimize protocols for reproducible tissue generation and maintenance. Test novel stem cell culture conditions, sort, screen, expand and differentiate hi PSCs according to latest protocols and newly developed approaches. Requirements of the Scientist/Sr. Scientist-Stem Cell Biology/Embryology: PhD in biological sciences, stem cell biology, genetics or related field. 2+ years hands-on expertise in stem cell culture (iPSCs/ESCs). Hands-on experience with mammalian embryos, including dissections and culture. Experience in molecular biology and strong problem solving skills.

Scientist, In Vivo Pharmacology - Permanent - Palo Alto, CA Where curiosity meets purpose-join us in shaping the future of science. Primary Responsibilities: Proclinical is seeking a highly motivated, dynamic Scientist to support in vivo research on our cutting-edge pipeline and discovery programs. You will be involved in the preparation and execution of murine animal experiments and the collation of data. The Scientist of In Vivo Pharmacology will: Preparation for and execution of translational experiments such as in vivo pharmacology and disease model experiments, including experiments in knockout and transgenic mice Animal handling during murine experiments, and handling of murine tissues resulting from animal experiments Management of relationships with third-party vendors on mouse breeding and shipping Identification, ordering, organization, storage, and proper disposal of laboratory reagents required for studies In collaboration with the Laboratory Biology team, aid in maintaining laboratory space and inventory Recording and filing data, preparing technical reports, and study summaries Report progress of projects in a timely and concise manner to supervisor May independently lead the development and implementation of new assays to support research projects; may independently execute experiments and perform data analyses of moderate complexity; may have responsibility for specific method or study. Occasionally provides assistance to and/or mentoring other technical staff, new research staff or interns Manages personal experimental timelines to meet project and personal goals Presents findings at the scientist, department, and site-level. Function as part of a collaborative team to support research needs Contribute to the optimal functioning of the research team, including implementation of new tools and technologies. Skills & Requirements: S. and 7+ years of laboratory experience (academic and/or industry) or M.S. with 5+ years of laboratory experience (academic and/or industry) Degree must be in a life sciences discipline, preferably cellular and/or molecular biology, biochemistry, and/or microbiology/immunology 3+ years of hands-on experience with in vivo murine research required, with mouse pharmacology and inflammation disease model experiments highly desired Experience in experimental techniques such as handling of animal tissue, cell culture, qRT-PCR, flow cytometry, and ELISAs/MSDs is required Experience in immunology research, including research with primary immune cells, would be valuable Must be highly organized, punctual, and precise both in regards to performing laboratory experiments as well as maintenance of the laboratory space. Ability to work independently and occasionally during non-traditional work hours as may be required by some experiments and will need to be comfortable in a laboratory and animal facility setting. Possesses effective problem-solving, organizational, and communication skills Experience with Microsoft software suite (Word, Excel, PowerPoint), and other commonly used computer applications (Zoom, MS Teams, Box, etc.) Clear and effective communicator across verbal, written, and interpersonal settings If you are interested in applying to this exciting opportunity, then please click 'Apply' or to speak to one of our specialists please request a call back at the top of this page. Proclinical is a leading life sciences recruiter focused on finding exceptional people and matching them with the finest positions across the globe. Proclinical is acting as an Employment Agency in relation to this vacancy. By submitting this application, you confirm that you've read and understood our privacy policy, which informs you how we process and safeguard your data - https://www.proclinical.com/privacy-policy

About our team: Our team is dedicated to revolutionizing B2B e-commerce through the development of a groundbreaking AI search product. Leveraging cutting-edge LLM technology, we're creating a brand new AI search engine and streamline the entire purchasing process for B2B customers. Responsibilities ● Deliver full projects by defining the data structure, framework, design, and evaluation metrics for AI solution development and implementation. ● Develop and deploy Large Language Models (LLMs) to empower search and agent systems for a variety of applications. ● Identify new and upcoming product innovation areas by interacting with potential external and internal collaborators. ● Identify undefined problems in existing technology and engage stakeholders and leaders to address them. Qualifications ● PhD, Master's, or Bachelor's degree in Computer Science, Engineering, Mathematics, or related fields. ● Ability to implement and verify state-of-the-art NLP or Computer Vision algorithms. ● Experience in successfully applying machine learning approaches to real-world personalization problems. ● Experience with building large language models. ● Knowledge of statistical methods, with strong mathematical skills. ● Excellent problem-solving and programming skills in Python. The pay range for this position at commencement of employment is expected to be between $196,500/year and $325,500/year. However, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Yoh is looking for a skilled and driven Senior Research Scientist, Biophysics with hands-on experience in small molecule drug discovery to join our collaborative Lead Discovery team. This is a lab-based role focused on the biophysical and mechanistic characterization of small molecule-protein interactions to support our drug discovery pipeline. This candidate must have hands on experience with designing and executing binding characterization studies using SPR. Industry: Discovery and Development Location: South San Francisco, CA Key Responsibilities: Design and execute binding characterization studies using SPR (Biacore S200 and 8K+). Conduct routine compound screening and mechanistic studies using biophysical assays (e.g., nano DSF, DLS, Spectral Shift). Manage and coordinate outsourced biophysical studies with CROs. Analyze and interpret data to support SAR and lead optimization across multiple projects. Maintain detailed experimental records and present findings in internal meetings and reports. Qualifications: PhD in Biophysics, Biochemistry, or a related field. Minimum 3 years of relevant industry experience in small molecule drug discovery biophysics. Proven expertise in SPR assay development and data interpretation. Demonstrated expertise in designing, developing, and interpreting biophysical characterization of small molecule-protein interactions by SPR. Strong familiarity with additional biophysical techniques (TSA, DLS, Spectral Shift, NMR, ITC, etc.). Proficiency with data analysis and graphing tools is a plus. #IND-SPG Estimated Min Rate: $70.00 Estimated Max Rate: $80.00 What's In It for You? We welcome you to be a part of the largest and legendary global staffing companies to meet your career aspirations. Yoh's network of client companies has been employing professionals like you for over 65 years in the U.S., UK and Canada. Join Yoh's extensive talent community that will provide you with access to Yoh's vast network of opportunities and gain access to this exclusive opportunity available to you. Benefit eligibility is in accordance with applicable laws and client requirements. Benefits include: Medical, Prescription, Dental & Vision Benefits (for employees working 20+ hours per week) Health Savings Account (HSA) (for employees working 20+ hours per week) Life & Disability Insurance (for employees working 20+ hours per week) MetLife Voluntary Benefits Employee Assistance Program (EAP) 401K Retirement Savings Plan Direct Deposit & weekly epayroll Referral Bonus Programs Certification and training opportunities Note: Any pay ranges displayed are estimations. Actual pay is determined by an applicant's experience, technical expertise, and other qualifications as listed in the job description. All qualified applicants are welcome to apply. Yoh, a Day & Zimmermann company, is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran. Visit ************************************************ to contact us if you are an individual with a disability and require accommodation in the application process. For California applicants, qualified applicants with arrest or conviction records will be considered for employment in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act. All of the material job duties described in this posting are job duties for which a criminal history may have a direct, adverse, and negative relationship potentially resulting in the withdrawal of a conditional offer of employment. It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. By applying and submitting your resume, you authorize Yoh to review and reformat your resume to meet Yoh's hiring clients' preferences. To learn more about Yoh's privacy practices, please see our Candidate Privacy Notice: **********************************

Stage: Seed Team Size: < 10 We're looking for an Applied RS who can run the gamut of ML from infra to modeling and own the entire ML pipeline--taking advanced models into production. Our ideal candidate will be looking to build a co-pilot product from the ground up: helping to drive everything from key architectural decisions, applying SOTA methods, and shipping advanced production models in close collaboration with the founders. In key role, you will have real product ownership and the chance to influence not just what gets built, but how it gets built in a true 0->1 scenario. If you have 5+ years of experience in Machine Learning (infra and modeling) with 1+ years post-training LLM's and are thinking about starting your own company someday, this could be a great entry-way for you. Not only would you get real-world experience with something so early, but you'd get a chance to make a name for yourself with our investment team as well (making it much easier to get a chance to pitch us on your own idea in the future). About Greylock Greylock is a 1st-tier, early-stage venture capital firm that partners with exceptional founders at the seed and Series A stages. Our mission is to help realize rare potential - backing category-defining companies such as Figma, Anthropic, Ramp, Abnormal Security, Rubrik, Airbnb, LinkedIn, Roblox, Dropbox, and Coinbase. About the Greylock Recruiting Team As full-time, salaried employees of Greylock, our team provides free candidate referrals and introductions to our active portfolio companies. Combined, we bring over 125 years of in-house recruiting experience across startups and large-scale tech companies

We are a group of people united by a strong purpose. We want you to get to know us, and Giuseppe, our very own artificial intelligence. We love good food, but above all, we love the planet, and that's why, to protect it, we reinvent the food industry, one delicious bite at a time, elevating what we eat, through our technology and based on plants. Our recipe has three mega-important components: science, technology, and of course, disruptive talents who work daily to create a better future. At NotCo we are not and do not seek to be the perfect company, but rather the right one. We are here to produce changes, and that is why we dare, fail, and sometimes achieve incredible successes. We are currently looking for a Product Development Scientist for our NotCo B2B Research & Development located in San Francisco, California, requiring an active on-site presence. This position will report to our R&D Sr. Team Lead and the incumbent will work cross-functionally to ensure R&D activities are successfully deployed locally. Responsible for the: Independently conducts day-to-day product development activities as directed by the manager across multiple projects. This includes supporting activities related to the full product lifecycle process (from product concept to successful commercial launch as needed)and supporting process development, scale-up and technology transfer Supports the design and execution of bench-top tests, pilot-plant trials and full-scale formulations to deliver high-quality food products that meet and exceed the sensory, cost, and other performance targets Proactively proposes and uses sensory and analytical analysis to guide and validate the development process Maintains detailed documentation, experiment tracking and outcomes, and documents finished goods and ingredient specifications Provides feedback to project lead regarding relevant technical and process information Communicates proactively and effectively with cross-functional teams, clearly articulating perspectives and trade-offs related to new product development goals Utilizes NotCo's proprietary AI technology to develop and improve food products Supports formula validation activities as well as process development, scale-up and technology transfer Engages in client communications and workshops, bringing technical Maintains detailed documentation across all R&D activities in a timely manner Qualifications / Requirements: Bachelor's degree in Food Engineering, Food Science, Engineering in Biotechnology or a similar discipline. 2 + years of Food R&D experience is desired, preferably across both food and beverage categories. Be agile, adaptable, and thrive in a dynamic and changing culture; works relentlessly to overachieve, anticipate obstacles, and create plans to overcome them. Adapts easily to changing priorities and direction based on new project learnings and team priorities. Demonstrated competency to effectively communicate (oral & written) cross-functionally with solid collaboration skills. Comfortable in client-facing situations and able to communicate complex topics clearly and simply. Excel in a startup environment, is excited to create new procedures and processes from scratch and has a strong entrepreneurial mindset. Be a problem solver, have a general manager mindset, and take the initiative to get the job done Possess strong planning, project management, and execution skills, and the ability to articulate where and how you have used them. Rigorous data-driven/analytical capability and ability and presence to present data effectively to a leadership team Work well in teams and cross-functional groups in a matrixed environment, both regionally and globally Possesses strong computer skills, including a high level of proficiency in MS Office, specifically Excel Authorization to work in the U.S. is required Ability to travel up to 50% of the time, including international travel and extended trips. NotCo is committed to fair and equitable compensation practices. The pay range for this role is $65,000 - $75,000. Actual compensation packages are based on several factors that are unique to each candidate, including but not limited to skill set, depth of experience, certifications, and specific work location. This may be different in other locations due to differences in the cost of labor. We are an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.

Our client is a research and development company whose mission is to harness advanced technologies to increase our understanding of the biology that controls lifespan. Support the team in establishing in vitro models of age-related neurodegenerative diseases aimed at target validation and mechanistic biology. Optimize existing protocols for iPSC-derived cell models. Follow quality control and reproducibility standards for the cell culture systems. Track and communicate the status of ongoing experiments with the team and iteratively optimize experiments Analyze, interpret data and rigorously document protocols, raw data and results.

ImmunEdge is a biopharmaceutical company committed to developing novel therapeutics for patients with serious or life-threatening diseases. With a highly experienced team of experts in immunology and drug development, we are pioneering innovative approaches to target and modulate key molecular pathways that regulate the immune response. At ImmunEdge, we are driven by a shared commitment to improving human health through innovative science. We are building a culture based on kindness, collaboration, and a deep passion for advancing science. As an early joiner to the company, you will help cultivate an environment where every team member is encouraged to challenge ideas, think critically, and contribute their unique perspectives. We value openness, transparency, and continuous learning, and want to empower our employees to take ownership of their work while fostering a sense of community and teamwork. Whether you're working in the lab, the office, or across functional teams, you will find an inclusive space where your contributions matter and your professional growth is supported. Join us in shaping the future of biotechnology. Together, we can change lives. Position: We're looking for a research associate/scientist to join the protein purification and analytics team in the Biotherapeutic Department. This role will be a fit for one who enjoys hands on science and wants to make a direct impact on the development of next-generation biologics. As part of the protein purification and characterization team, you'll contribute to the production and characterization of therapeutic proteins and antibodies, with an emphasis on complex biologics such as bispecific antibodies, as well as challenging antigens. The successful candidate will be responsible for executing purification processes and various biochemical/biophysical analytics to support our pipeline. Key Responsibilities: Execute purification workflows for mono-clonal and bispecific/multi-specific antibodies, and other therapeutic proteins, using appropriate chromatographic techniques, including affinity, IEX, HIC, SEC, and mixed modes. Characterize biomass (as needed) and purified molecules for quality attributes (expression titter, molecule assembly quality, protein identity, purity, aggregation, charge heterogeneity, PTMs). Optimize purification process for small-scale and large-scale productions to support discovery, lead optimization, and preclinical studies. Troubleshoot production and purification challenges and improve process to enhance yield and purity; provide insights and feedback for molecule redesign or engineering when issues are tied to intrinsic sequence problems. Maintain detailed documentation of experiments, including materials, protocols, results, and conclusions, in electronic lab notebooks and technical reports. Present updates to cross-functional project teams and group or department meetings. Qualifications: Bachelor's degree with minimum 5 years of related industry experience, or PhD in relevant field. Level will be commensurate with experience. Understanding of protein biochemistry, structure and function relationship, hands-on experience with protein purification and characterization. Strong analytical skills and experience with protein structure modeling/illustration and sequence analysis/alignments. Excellent communication skills and teamwork spirit. Experience with high-throughput protein purification or large-scale purification is desired. Experience with membrane protein purification or structural characterization is a plus. Knowledge of bispecific antibody engineering and optimization is a plus. Advanced knowledge or experience with mass spectrometry techniques (including LC-MS, tandem MSMS) and/or biosensor (e.g. SPR, BLI) technology is a plus. Expected Salary Range: $106,000 - $139,000 We encourage candidates of all levels to apply as there is sometimes flexibility on job level and responsibilities. Compensation will be based on a variety of factors, including experience, qualifications, internal equity, and location. ImmunEdge offers a competitive employment package that includes an annual bonus plan, equity, and a generous benefits package including comprehensive health (medical, dental, and vision) insurance for our employees and their families, a 401k plan, FSA plans (medical, dependent), an Employee Assistance Plan, and a holiday and paid time off plan. At ImmunEdge, we believe that a diverse, open, and inclusive environment and culture is key to our success. We will not be influenced in recruiting, hiring, promoting or any other employment practices by race, color, citizenship status, national origin, ancestry, sex, sexual orientation, gender identity/expression, age, religion, physical or mental disability, medical or genetic condition, marital status, veteran status, or any other characteristics protected under applicable federal, state and local laws. ImmunEdge will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable laws. Note to External Recruiters: Submission of unsolicited resumes prior to an agreement set in place does not create any implied obligation.

Job Description ImmunEdge is a biopharmaceutical company committed to developing novel therapeutics for patients with serious or life-threatening diseases. With a highly experienced team of experts in immunology and drug development, we are pioneering innovative approaches to target and modulate key molecular pathways that regulate the immune response. At ImmunEdge, we are driven by a shared commitment to improving human health through innovative science. We are building a culture based on kindness, collaboration, and a deep passion for advancing science. As an early joiner to the company, you will help cultivate an environment where every team member is encouraged to challenge ideas, think critically, and contribute their unique perspectives. We value openness, transparency, and continuous learning, and want to empower our employees to take ownership of their work while fostering a sense of community and teamwork. Whether you're working in the lab, the office, or across functional teams, you will find an inclusive space where your contributions matter and your professional growth is supported. Join us in shaping the future of biotechnology. Together, we can change lives. Position: We're looking for a research associate/scientist to join the protein purification and analytics team in the Biotherapeutic Department. This role will be a fit for one who enjoys hands on science and wants to make a direct impact on the development of next-generation biologics. As part of the protein purification and characterization team, you'll contribute to the production and characterization of therapeutic proteins and antibodies, with an emphasis on complex biologics such as bispecific antibodies, as well as challenging antigens. The successful candidate will be responsible for executing purification processes and various biochemical/biophysical analytics to support our pipeline. Key Responsibilities: Execute purification workflows for mono-clonal and bispecific/multi-specific antibodies, and other therapeutic proteins, using appropriate chromatographic techniques, including affinity, IEX, HIC, SEC, and mixed modes. Characterize biomass (as needed) and purified molecules for quality attributes (expression titter, molecule assembly quality, protein identity, purity, aggregation, charge heterogeneity, PTMs). Optimize purification process for small-scale and large-scale productions to support discovery, lead optimization, and preclinical studies. Troubleshoot production and purification challenges and improve process to enhance yield and purity; provide insights and feedback for molecule redesign or engineering when issues are tied to intrinsic sequence problems. Maintain detailed documentation of experiments, including materials, protocols, results, and conclusions, in electronic lab notebooks and technical reports. Present updates to cross-functional project teams and group or department meetings. Qualifications: Bachelor's degree with minimum 5 years of related industry experience, or PhD in relevant field. Level will be commensurate with experience. Understanding of protein biochemistry, structure and function relationship, hands-on experience with protein purification and characterization. Strong analytical skills and experience with protein structure modeling/illustration and sequence analysis/alignments. Excellent communication skills and teamwork spirit. Experience with high-throughput protein purification or large-scale purification is desired. Experience with membrane protein purification or structural characterization is a plus. Knowledge of bispecific antibody engineering and optimization is a plus. Advanced knowledge or experience with mass spectrometry techniques (including LC-MS, tandem MSMS) and/or biosensor (e.g. SPR, BLI) technology is a plus. Expected Salary Range: $106,000 - $139,000 We encourage candidates of all levels to apply as there is sometimes flexibility on job level and responsibilities. Compensation will be based on a variety of factors, including experience, qualifications, internal equity, and location. ImmunEdge offers a competitive employment package that includes an annual bonus plan, equity, and a generous benefits package including comprehensive health (medical, dental, and vision) insurance for our employees and their families, a 401k plan, FSA plans (medical, dependent), an Employee Assistance Plan, and a holiday and paid time off plan. At ImmunEdge, we believe that a diverse, open, and inclusive environment and culture is key to our success. We will not be influenced in recruiting, hiring, promoting or any other employment practices by race, color, citizenship status, national origin, ancestry, sex, sexual orientation, gender identity/expression, age, religion, physical or mental disability, medical or genetic condition, marital status, veteran status, or any other characteristics protected under applicable federal, state and local laws. ImmunEdge will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable laws. Note to External Recruiters: Submission of unsolicited resumes prior to an agreement set in place does not create any implied obligation. Powered by JazzHR Jc766epfad

Senior Research Associate/Associate Scientist, Protein Biochemistry Allakos Inc. is a clinical-stage company developing therapeutic antibodies for inhibitory receptors on the surface of immune effector cells involved in allergic, inflammatory and proliferative diseases. Allakos is committed to developing innovative therapies that transform patients' lives. We are looking for bright and talented individuals to join our team and share in our passion and commitment to improving the lives of patients. We are seeking a highly motivated Senior Research Associate/Associate Scientist with a strong background in protein biochemistry to join our R&D team. The selected candidate will be responsible for generating reagents for the department to support our lead and preclinical antibody programs. This position will provide the candidate an opportunity to perform a wide range of activities and to expand/learn new techniques. Your Role: Perform protein expression, purification, and modification of proteins and antibodies Characterize purified proteins using established protocols Assist in developing new assays to characterize purified proteins Assist in biochemically screening monoclonal antibodies for new targets Assist in managing monoclonal antibody campaigns for new therapeutic targets Produce reports and protocols Present regular research updates to project teams and R&D management Qualifications and Expertise: B.S. or M.S. in Biological Sciences or related discipline with a minimum of 3-4 years relevant industry experience In-depth knowledge of protein biochemistry Proficient use of AKTA systems for protein purification Protein Characterization techniques such as SDS-PAGE, UV spectroscopy, and HPLC Tissue culture experience a plus but not required Excellent organization and troubleshooting skills Strong interpersonal communication skills Ability to work cooperatively in a team-based environment Flexibility in prioritizing work and ability to multitask and successfully interact to meat deadlines This position is located in Redwood City, CA. The salary is competitive and commensurate with experience and qualifications. The Allakos Values are: Selflessness, Drive, Clarity, Thoughtfulness, Fun, and Leadership Allakos is an equal opportunity employer. Allakos will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law.

About the Company We are a seed-stage AI company building the industry standard for evaluating and benchmarking large language models on real enterprise tasks. About the Role As a Research Scientist, you will develop new benchmarks, methodologies, and evaluation pipelines that shape how cutting-edge models are assessed, compared, and deployed in production environments. Your work will directly influence model selection and safety decisions across foundation model labs, high-growth AI product companies, and Fortune-scale enterprises. Responsibilities Benchmarking & Model Analysis Evaluate newly released models as they launch (e.g., Gemini, DeepSeek, etc.) Run large-scale assessment workflows using internal evaluation infrastructure Compare model performance across enterprise-grade task categories Design New Benchmarks from Scratch Identify high-value model application domains through research exploration Construct datasets, including labeling strategy and workforce coordination Write short “white-paper-style” summaries explaining benchmark purpose, method, and findings Advance Automated Evaluation Methodologies Improve systems for scoring generated text beyond standard metrics Explore research in reference-free, rubric-based, and human-aligned evaluation Develop new techniques for reliability, consistency, and repeatability Cross-functional Collaboration Work closely with engineering to scale evaluation infra Partner with customers to refine evaluation relevance and task fit Influence product direction through research insights Qualifications 0-3 years post-grad experience (Master's, PhD, or equivalent applied research) Publications, preprints, or demos showing cutting-edge work Experience with diffusion models, NLP, multimodal, or benchmarking work Ability to operate independently with ambiguity Clean, maintainable research codebases Candidates from: top engineering/research universities applied AI startups well-regarded research internships Required Skills Built or contributed to a benchmark or evaluation methodology Experience in enterprise task model evaluation Stanford / top lab adjacency (per their historical hiring success) Preferred Skills Wants to publish as primary motivation Purely academic with slow timelines Big-tech culture fit concerns (Meta / Google / Salesforce specifically noted-but case-by-case) Pay range and compensation package Base Salary: up to $250K depending on background Equity: typically 0.3% - 0.5%, flexibility for exceptional candidates Rapid equity refresh possible based on impact Equal Opportunity Statement Visa sponsorship available. Relocation support. Health & dental coverage. Lunch + dinner provided, snacks & coffee. Unlimited PTO. Weekly happy hours with community guests. Team events (bowling, hiking, rock climbing, etc.). Swag program (hats, etc.). Work Environment & Culture In-person, San Francisco HQ (required). Core hours: 9-5, some teammates extend voluntarily. Most team members work 1 weekend day per week (flexible). High-ownership, low-ego, collaborative. Live demos Mondays, team lunch Thursdays, community Fridays. Early-stage pace, applied focus-not academic publishing. Tech Environment (while research-focused, exposure beneficial) Backend: Python / Django. Frontend: React + TypeScript. Infra: AWS. Evaluation frameworks + internal tooling. Why This Role Is Unique The company already collaborates with foundation model labs, high-growth AI vertical product companies, and Fortune 500 enterprises (not publicly facing). ChatGPT Vals AI $5M seed raised, runway of 2+ years at current burn. Only one research scientist is being hired-true founding impact. Opportunity to define industry standards for model trust, reliability, and certification. Positioned to become the rating agency for generative AI.

Join a Leading Applied Research Lab Pushing the Boundaries of Reinforcement Learning Are you passionate about advancing the frontiers of reinforcement learning (RL)? An innovative AI research lab is seeking talented and ambitious scientists to shape the next generation of RL techniques-especially where they intersect with large models and environment generation. About the Role As an AI Research Scientist focused on RL, you will: Develop novel optimization-based methods for automated RL environment generation Establish baselines for evaluating the quality and diversity of RL environments Design infrastructure to create dynamic environments from historical datasets and agent evaluations Drive your own research agenda, contributing directly to the progress of our platform and the broader AI community What We're Looking For PhD (or equivalent experience) in machine learning, computer science or a related field Strong publication record and/or evidence of research impact (open source, deployed systems, etc.) Deep expertise in reinforcement learning and machine learning fundamentals Proficient in Python and at least one modern ML framework (such as PyTorch or JAX) Bonus Points Experience with post-training large language models (LLMs) Demonstrated software engineering skills Ability to communicate research findings effectively to both technical and non-technical audiences

We are a group of people united by a strong purpose. We want you to get to know us, and Giuseppe, our very own artificial intelligence. We love good food, but above all, we love the planet, and that's why, to protect it, we reinvent the food industry, one delicious bite at a time, elevating what we eat, through our technology and based on plants. Our recipe has three mega-important components: science, technology, and of course, disruptive talents who work daily to create a better future. At NotCo we are not and do not seek to be the perfect company, but rather the right one. We are here to produce changes, and that is why we dare, fail, and sometimes achieve incredible successes. We are currently looking for a Product Development Scientist for our NotCo B2B Research & Development located in San Francisco, California, requiring an active on-site presence. This position will report to our R&D Sr. Team Lead and the incumbent will work cross-functionally to ensure R&D activities are successfully deployed locally. Responsible for the: Independently conducts day-to-day product development activities as directed by the manager across multiple projects. This includes supporting activities related to the full product lifecycle process (from product concept to successful commercial launch as needed)and supporting process development, scale-up and technology transfer Supports the design and execution of bench-top tests, pilot-plant trials and full-scale formulations to deliver high-quality food products that meet and exceed the sensory, cost, and other performance targets Proactively proposes and uses sensory and analytical analysis to guide and validate the development process Maintains detailed documentation, experiment tracking and outcomes, and documents finished goods and ingredient specifications Provides feedback to project lead regarding relevant technical and process information Communicates proactively and effectively with cross-functional teams, clearly articulating perspectives and trade-offs related to new product development goals Utilizes NotCo's proprietary AI technology to develop and improve food products Supports formula validation activities as well as process development, scale-up and technology transfer Engages in client communications and workshops, bringing technical Maintains detailed documentation across all R&D activities in a timely manner Qualifications / Requirements: Bachelor's degree in Food Engineering, Food Science, Engineering in Biotechnology or a similar discipline. 2 + years of Food R&D experience is desired, preferably across both food and beverage categories. Be agile, adaptable, and thrive in a dynamic and changing culture; works relentlessly to overachieve, anticipate obstacles, and create plans to overcome them. Adapts easily to changing priorities and direction based on new project learnings and team priorities. Demonstrated competency to effectively communicate (oral & written) cross-functionally with solid collaboration skills. Comfortable in client-facing situations and able to communicate complex topics clearly and simply. Excel in a startup environment, is excited to create new procedures and processes from scratch and has a strong entrepreneurial mindset. Be a problem solver, have a general manager mindset, and take the initiative to get the job done Possess strong planning, project management, and execution skills, and the ability to articulate where and how you have used them. Rigorous data-driven/analytical capability and ability and presence to present data effectively to a leadership team Work well in teams and cross-functional groups in a matrixed environment, both regionally and globally Possesses strong computer skills, including a high level of proficiency in MS Office, specifically Excel Authorization to work in the U.S. is required Ability to travel up to 50% of the time, including international travel and extended trips. NotCo is committed to fair and equitable compensation practices. The pay range for this role is $65,000 - $75,000. Actual compensation packages are based on several factors that are unique to each candidate, including but not limited to skill set, depth of experience, certifications, and specific work location. This may be different in other locations due to differences in the cost of labor. We are an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.