Scientist
Principal research scientist job in Devens, MA
Job Title: Scientist
Duration: 12 months
Pay range: $70 to $75.21/hr on W2
Onsite/hybrid: 50% onsite (Tue, Wed, Thurs). First month will need to be onsite every day.
Work hours: 40 hours, Core hours are 9:00 - 4:00
Top 3 to 5 Skills or Must haves:
Demonstrated Technical Writing Ability.
Worked in Cross matrix Teams.
Project Management - fast paced environment and can manage multiple projects at once.
Independent Contributor - personable and can work with multiple stakeholders.
Change Controls - GMP environments preferred.
Investigation Experience.
Bio Pharma experience preferred.
Job Description:
The Scientist in Manufacturing Sciences & Technology will support the Materials and Cryogenics Science group in the life cycle management of raw materials, consumables and single-use systems utilized for biopharmaceuticals commercial manufacturing operations. The successful candidate will collaborate closely with Manufacturing, Manufacturing Technology, Quality Assurance, Quality Control, Supply Chain, and Global Procurement groups on cross-functional teams.
The subject matter expert for this position will be primarily required to:
Qualify alternative raw material suppliers:
Work with procurement to identify new suppliers.
Recommend and/or lead necessary testing to qualify material for use in GMP manufacturing.
Author technical equivalency assessments, specification comparisons and material characterization reports.
Support risk assessments.
Author change controls.
Additional Tasks would include:
Support material and consumable manufacturing investigations.
Evaluate and manage material associated supplier changes notifications to maintain GMP compliance.
Support material specification development.
Requirements:
Minimum BS/MS with 2+ years of industry experience post-graduation or PhD in Material Science Engineering, Chemistry or equivalent scientific background.
Awareness of cGMP compliance and regulatory agency requirements.
Demonstrated problem solving ability (familiarity with root cause analysis techniques and CAPAs a plus).
Strong organizational, oral communication and technical writing skills.
Effective team player and strong individual contributor.
Familiarity with analytical techniques (FTIR, SEM-EDS, etc.).
Knowledge of data trending and tracking, including use of statistical analysis software a plus
Travel requirements: No
Physical requirements: No
Additional Job Requirements:
Lab w/o blood & animal
Machine Learning Scientist
Principal research scientist job in Boston, MA
Machine Learning Scientist - Generative Audio (Series C, Cutting-Edge Research Environment)
Join a research-driven ML team building the most advanced generative audio technology in the world. This is a rare chance to shape the future of music creation where cutting-edge model development meets real creative impact for millions of users globally.
We're a well-funded Series C startup backed by top-tier investors (Lightspeed, Menlo) with a ~120-person team. You'll get the fast-moving ownership of an early-stage environment
with
the stability, compute, and compensation of a later-stage company.
As an ML Scientist, you'll work directly with the founding team and an experienced group of research scientists and engineers. You'll run your own research initiatives, explore new approaches for generative audio, and train models at a scale very few startups offer an H100-per-scientist ratio of well over 100×.
What you'll work on:
Owning and running independent research projects that push the boundaries of generative audio
Training state-of-the-art models using PyTorch
Optimizing training and inference pipelines on hundreds of H100s
Developing methods that make AI-generated music more appealing, expressive, and widely accessible
What makes this opportunity unique:
Revolutionary platform: Help power the world's leading AI music creation system used by everyone from beginners to professional artists
Massive impact: Your work directly improves the creative output of millions
Unmatched compute: Access to one of the most GPU-rich environments in any startup
Founder proximity: Work closely with co-founders on high-leverage research and technical strategy
What we're looking for:
3+ years of ML research experience
Demonstrated success training state-of-the-art generative models
Prior work in audio or music ML (industry or published research)
Advanced studies in ML, audio DSP, or related fields (Master's or PhD preferred)
Strong PyTorch skills and solid baseline software engineering ability
Familiarity with our product and mission-and ideally, a genuine love of music
Based onsite in Cambridge/Boston, New York City or Los Angeles
This is an ideal role for someone who's excited by deep research, massive scale, and the chance to define the next era of generative audio. If music inspires you and large-model experimentation motivates you, you'll thrive here.
Senior Assay Development Scientist/Engineer
Principal research scientist job in Burlington, MA
+++
SiPhox Health is redefining clinical immunoassay diagnostics by miniaturizing the analytical power of a central lab into an accessible, affordable, at-home platform. Our silicon-photonics architecture unites advanced biochemistry, microfluidics, and semiconductor-grade manufacturing to deliver precise, multiplexed biomarker quantification in minutes on a device the size of a coffee maker.
We are building what we believe will become the first mass-market photonic blood analyzer, enabling continuous improvement in chronic disease management through frequent, high-quality testing.
+++ The Opportunity +++
We are looking for a Senior Assay Development Scientist or Engineer who wants to build assays that have never been built on this kind of platform before. If you thrive on developing rigorous, quantitative immunoassays, including challenging free/competitive assays, and want your work to directly ship in a consumer device used by millions, this is one of the rarest opportunities in diagnostics today.
This role sits at the center of platform innovation, contributing directly to analytical chemistry, surface chemistry, microfluidics, and silicon photonics integration. You will shape a growing assay menu that spans hormones, inflammatory markers, metabolic proteins, and future pediatric/specialty panels.
+++ What You'll Do +++
Core Assay Development
Develop quantitative sandwich and competitive immunoassays (including free hormone assays, displacement-driven formats, and low-abundance biomarkers) on a silicon-photonic resonance platform.
Design, execute, and interpret experiments focused on:
Binding kinetics & equilibrium optimization
Surface functionalization strategies
Competitive assay dynamic-range shaping
Calibrator and control development (matrix selection, commutability)
Assay precision, stability, robustness
Analytical Performance & Validation
Own assay verification and validation aligned with CLSI standards (EP05, EP06, EP07, EP09, EP10, EP17).
Establish and demonstrate performance for:
Analytical sensitivity & functional limit (LoB/LoD/LoQ)
Linearity & reportable range (including hook effects, competitive assay inflection characterization)
Repeatability, reproducibility, and nested CV analysis
Interference and cross-reactivity studies
Matrix equivalency & recovery studies
Build calibration models for a novel platform (e.g., 4PL/5PL, competitive curve inversion, chip-specific normalization frameworks).
Cross-Functional Integration
Collaborate deeply with photonics, microfluidics, reader electronics, manufacturing, and product engineering teams to close the loop on real-world assay performance.
Work with process development and chemistry groups to scale assays from prototype to production, enabling high-volume, chip-based manufacturing.
Documentation & Execution
Deliver high-clarity technical reports, protocols, V&V documentation, and design-history file content that meets IVD and FDA expectations.
Present results across the company to inform design decisions and product milestones.
+++ What We're Looking For +++
Technical Background
PhD + 2 years, or MS + 6 years in biochemistry, chemical engineering, analytical chemistry, biophysics, bioengineering, or related fields.
Expertise in immunoassay development (sandwich and competitive). Experience with free hormone assays is a major plus.
Demonstrated ability to independently solve complex analytical and biochemical problems.
Hands-on experience with complex analytical workflows, assay automation, and instrumentation.
Strong understanding of calibration design, commutability, and control strategies.
Familiarity with statistical analysis of assay performance, including mixed-model ANOVA, CV decomposition, and method-comparison frameworks.
Regulatory & Platform Experience (Bonus)
Experience with IVD development, ISO 13485, or 21 CFR 820.
Experience with POC or novel-platform assay development.
Knowledge of label-free sensors, waveguides, or photonic resonance systems.
Experience with Python, R, or MATLAB for data analysis, curve fitting, and automation.
Personal Traits
Strong scientific intuition paired with rigorous data discipline.
Thrives in a fast-paced, milestone-driven startup environment.
Creative problem solver willing to challenge established assay paradigms.
High integrity, willingness to own outcomes, and a collaborative mindset.
+++ Why This Role Is Unique +++
Most assay developers spend their careers optimizing assays on platforms that already exist.
At SiPhox, you will:
Build the first generation of photonic immunoassays deployed in consumer health.
Design assays whose constraints are shaped by semiconductor physics as much as biochemistry.
Work on hard problems (free hormone assays, multiplexing, competitive equilibrium, small-volume matrices) where innovation, not incrementalism, wins.
See your work ship in a product used at home by real people, not just research labs.
If you want to work at the frontier of diagnostics (where photonics, biochemistry, and consumer health converge) we'd love to meet you.
Senior Research Scientist - Material Flammability, Fire Dynamics and Lithium-ion Battery Safety
Principal research scientist job in Norwood, MA
Established nearly two centuries ago, FM is a leading mutual insurance company whose capital, scientific research capability and engineering expertise are solely dedicated to property risk management and the resilience of its policyholder-owners. These owners, who share the belief that the majority of property loss is preventable, represent many of the world's largest organizations, including one of every four Fortune 500 companies. They work with FM to better understand the hazards that can impact their business continuity to make cost-effective risk management decisions, combining property loss prevention with insurance protection.
The purpose of this position is to develop new scientific knowledge, technologies and engineering solutions to problems in material flammability, fire dynamics and Lithium-ion battery safety research, which can be used for the prevention or control of industrial property loss.
The principal responsibilities are to carry out research projects in the areas of flammability, fire spread, and heat transfer in fires from solid combustible as well as Lithium-ion batteries. Key areas of research include understanding of fire behavior at the medium and large scales via bench-scale experiments and theoretical models on material flammability and flame heat transfer. Projects can also involve advanced flame diagnostic of buoyant turbulent sooty flames and wall fires. The experimental and theoretical studies will be closely integrated with Computational Fluid Dynamic (CFD) model development and validation within the work group.
The position is responsible for all aspects of project management including project proposals, execution, and reporting.
The position requires a PhD in Mechanical, Chemical Engineering, Fire Protection Engineering, or related fields with a strong fundamental background in combustion, fluid mechanics, heat transfer, material science and applied mathematics. Extensive experience in experimental methods in thermal fluids, material flammability, heat transfer, combustion/fire, and an understanding of associated numerical methods are required. Research experience with advanced laser diagnostics in flame, experimental measurement in turbulent flame, heat transfer and failure analysis of battery is desirable. Also needed are excellent written and verbal communication skills, as well as demonstrated expertise in developing solutions to challenging technical problems.
The final salary offer will vary based on geographic location, individual education, skills, and experience. The position is eligible to participate in FM's comprehensive Total Rewards program that includes an incentive plan, generous health and well-being programs, a 401(k) and pension plan, career development opportunities, tuition reimbursement, flexible work, time off allowances and much more.
FM is an Equal Opportunity Employer and is committed to attracting, developing, and retaining a diverse workforce.
#FMG
#LI-TA1
Auto-ApplyResearch Scientist & Antibody Computational Analysis
Principal research scientist job in Cambridge, MA
Site: The General Hospital Corporation
Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.
The DeKosky Laboratory for Immune Engineering and Drug Discovery (******************* Google Scholar: ************************************************************ is hiring a scientist to advance computational drug design and discovery, including the use of artificial intelligence (AI) and machine learning (ML) techniques.
The hired candidate will focus on computational aspects of immune repertoire analyses of antibody functional screening data. These efforts will advance methods for rapid machine learning-based antibody drug design while developing new and improved antibody drug products. We are looking for enthusiastic individuals that are curious about computational drug discovery and immunology, and want to participate in the exciting world of diving deeply into understanding how computational data and molecular design can be applied to discovery new drugs and fight diseases. The selected candidate will join a dynamic research team at the forefront of antibody engineering. These projects are fully funded by the several organizations, including the US National Institutes of Health and collaborative projects with the Bill and Melinda Gates Foundation, with several ongoing efforts and new projects ready to begin.
The Ragon Institute is an internationally renowned immunology-focused research center located in Kendall Square, Cambridge, Massachusetts, and with affiliations with MGH, Harvard, and MIT. This position is ideal for individuals who are interested in launching a career as biomedical research leaders in either academia or industry. Successful candidates will be immersed in a rich scientific community and become experts in advanced high-throughput drug development and establish cutting-edge drug screening approaches while being a part of a supportive, highly collaborative research environment with state-of-the-art facilities. The hired candidate will also be an affiliate of MIT, with access to MIT campus research resources and community facilities.
Job Summary
In consultation with their Principal Investigator (PI), undertake and execute a program of scientific study culminating in publication. Drives research projects scientifically and determines the course of research as evidenced by leadership, obtaining funding, writing, or other recognition. May not necessarily receive independent resources; however, their contribution is essential to the conceptual/scientific success of the project. They assist their PI in the training and supervision of other laboratory personnel and in a wide variety of administrative tasks, as necessary.
Does this position require Patient Care? No
Essential Functions
-Makes proficient intellectual contributions to scientific strategies of the group/lab and plays a leadership role by acting as subject matter authority in the field.
-Contributes to the design and execution of experiments and/or research projects.
-Exercises judgment in selecting methods and technologies to obtain results.
-May collaborate with external researchers and/or receive external project funding support.
-Presents results and prepares publications.
-May assist PI in the training and supervision of other staff.
Qualifications
Education
Doctorate Related Field of Study required
Can this role accept experience in lieu of a degree? No
Licenses and Credentials
Experience
Previous Research experience (inclusive of graduate and postdoctoral experience) 5-7 years required
Knowledge, Skills and Abilities
- Excellent research skills.
- Demonstrated evidence of specific scientific competence in field.
- Demonstrated broad knowledge of field.
- Evidence of potential for scientific creativity and original though.
- Able to exercise independent judgment and leadership.
- Ability to contribute to publications.
Additional Job Details (if applicable)
The salary range for this position is 80,000.00 to $105,000.00 annually.
At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience, if applicable, education, certifications, and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package.
In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums, and bonuses as applicable, and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.
Remote Type
Onsite
Work Location
600 Main Street
Scheduled Weekly Hours
40
Employee Type
Regular
Work Shift
Day (United States of America)
EEO Statement:
The General Hospital Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at **************.
Mass General Brigham Competency Framework
At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
Auto-ApplySenior Research Associate/Associate Scientist, Preclinical Formulation Development
Principal research scientist job in Cambridge, MA
What if… you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies in order to transform health care and sustainability?
Expedition Medicines Inc., is a privately held, early-stage biotechnology company pioneering the emerging field of Protein Editing. At Expedition Medicines we create small molecules that edit protein structure and function to unlock presently undruggable targets and a broad array of therapeutic modalities. Our platform integrates novel small molecule chemistry and chemoproteomic discovery technologies with Machine Learning (ML) to enable generative design. Expedition Medicines is backed by Flagship Pioneering, bringing their courage, vision, and resources to guide Expedition Medicines from platform validation to patient impact. We are seeking collaborative, relentless problem solvers that share our passion for impact to join us!
THE ROLE
The Formulation team is seeking a highly motivated, attentive and self-driven candidate to join our team and contribute to the development of discovery compounds as an Senior Research Associate/Associate Scientist. This successful candidate will join an energizing and collaborative research environment working as part of cross function drug discovery teams in providing a develop-ability assessment of innovative molecules.
KEY RESPONSIBILITIES
Execute stage appropriate, fit-for-purpose preclinical formulations preparation (Solutions, suspensions, emulsions, nanoparticles, SEDDS etc.) for oral, and parenteral formulations on a small scale for small molecules
Author protocols describing preparation of formulations for use at internal and external formulation labs
Basic drug substance characterization by using techniques such as HPLC/UPLC, XRPD, DSC and PLM. Assessment of the chemical and physical properties of small molecules, such as solubility, dissolution, particle size and chemical stability
Routine lab support such as buffer and mobile phase preparation, pH meter calibration, basic troubleshooting of lab equipment, and coordinating with external instrument and service vendors. Shipping and receiving samples between internal and external sites
Summarize experimental results and presents at team meetings and department presentations
Author templated memos and reports with limited guidance
Maintain detailed lab notebooks and reports in compliance with GLP/GMP guidelines (as applicable)
Evaluate novel drug delivery systems (e.g., lipid-based, amorphous solid dispersions, spray dry etc.) for poorly soluble compounds
Support transition of formulations from discovery to clinical development (e.g., bridging studies)
Independently design and perform focused experiments that drive progress in cross-functional formulation initiatives
PROFESSIONAL EXPERIENCE & QUALIFICATIONS
B.S. or M.S. in Chemistry, Biochemistry, Chemical Engineering, or a related discipline is required
Three years minimum of industry, government or equivalent experience in small molecules formulation or a related field
Hands-on experience with one or more of the following techniques: HPLC, UV-visible, DSC etc
Experience with data analysis using standard software platforms (Excel, Prism etc.)
Practical experience in developing and preparing preclinical formulations (small molecules)
Basic knowledge of physicochemical properties and their relationship to formulation development
Basic knowledge of pharmacokinetics (PK) and biopharmaceutics principles
The ability to manage multiple parallel activities and deliver results to agreed timelines
Ability to do bench work independently
Strong collaboration, problem-solving, and adaptability in fast-paced research environments
Excellent written, oral, and visual communication skills
Excellent time management skills
LOCATION: Cambridge, MA
ABOUT FLAGSHIP PIONEERING
Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity's most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.
Flagship has been recognized twice on FORTUNE's “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company's annual list of the World's Most Innovative Companies. Learn more about Flagship at ***************************
At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.
We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.
We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.
Recruitment & Staffing Agencies
: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.
#LI-MB1
The salary range for this role is $81,000 - $126,500. Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. Expedition Medicines currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Expedition Medicine's good faith estimate as of the date of publication and may be modified in the future.
Auto-ApplySenior Scientist / Associate Principal Scientist, Chemical Engineering R&D
Principal research scientist job in Coventry, RI
Job Title: Senior Scientist / Associate Principal Scientist, Chemical Engineering R&D
FLSA Status: Exempt
Salary: $100,000-$160,0000
Pharmaron is a global CRO helping pharma and biotech companies bring new therapies to life. With over 21,000 employees worldwide across 23 locations in the US, UK and China, we support drug discovery through to manufacturing with fully integrated, high-quality services.
We're proud of the impact we make and just last year, we supported over 780 discovery projects, 1,000+ CMC programmes, and 1,000+ clinical trials across all phases. Our teams are involved in everything from small molecules to biologics and gene therapies, and we work with more than 3,000 global customers. To learn more, visit ******************
About the Role
The Pharmaron Process Chemistry department is seeking highly motivated Chemical Engineers for an exciting role involving hands-on small-molecule process development and scale-up from laboratory to commercial manufacturing. Engineers in this position will design, plan, and implement both chemistry laboratory and in-silico experiments to support process and technology development for active pharmaceutical ingredients (APIs). This position will combine elements of chemistry, engineering, technology development, and data analysis to optimize manufacturing processes.
Strong teamwork, innovation, creativity, and organizational skills are essential, along with clear and confident communication to address technical challenges. Effective collaboration across multidisciplinary teams in the US, UK, and China, is critical, and a strong commitment to safety, quality compliance, and technical leadership is expected throughout all activities.
Key Responsibilities
Perform hands-on small molecule process development and scale-up work.
Use Design of Experiments (DoE) for process screening, optimization, and robustness studies.
Define CPPs, PARs, NORs, and contribute to the development of scalable control strategies.
Apply process analytical technology (PAT) and process modeling.
Evaluate and model kinetics, mixing, mass/heat transfer, and reactor performance.
Conduct independent research to achieve mechanistic understanding for rational process design.
Design and optimize key unit operations including crystallization, filtration, drying, distillation, and extraction.
Use process modeling tools to inform scale-up strategies.
Translate lab-scale findings into actionable parameters for kilo lab and GMP manufacturing.
Drive cycle time reduction and process intensification initiatives.
Implement innovative technologies such as continuous flow chemistry and automation platforms.
Support internal and external tech transfer activities, including scale-up studies, modeling, and verification experiments.
Support development of complex transformations such as catalytic hydrogenation.
Exhibit a mindset of safety and quality compliance.
Collaborate cross-functionally within US, UK, and China-based teams.
Required Experience & Skills
Education Minimum Requirement: The position requires either a BS and/or MS in Chemical Engineering (or comparable) from an accredited college/university plus at least 5 years of relevant work experience in small-molecule chemical process development - OR - a PhD in Chemical Engineering (or comparable) from an accredited college/university with at least 2 years of relevant work experience post PhD defense.
Experience performing lab-based research/process development in a chemical engineering-related area.
Experience with organic chemical synthesis and wet chemistry.
Experience with small molecule pharmaceutical drug substance development.
Experience applying statistical experimental design (i.e. Design of Experiments) and/or process modeling.
A high level of innovation, creativity, and self-initiative.
Highly effective communication and collaboration skills.
Good organizational, interpersonal, writing, and time management skills.
Preferred Experience & Skills
Experience with process scale-up and/or technology transfer, moving from laboratory to pilot plant or production scale.
Familiarity with concepts and application of cGMP and GDP during pharmaceutical development and production.
Demonstrated experience with chemical engineering-related technology development.
Familiarity with kilo-scale laboratory equipment.
Experience with process modeling (e.g., population balance modeling, distillation modeling).
Knowledge with milling equipment (spiral jet mills, pin mills, co-mills, rotor-stator wet mills).
Why Pharmaron?
Collaborative Culture: Thrive in our inclusive and collaborative environment, where teamwork and innovation go hand in hand. Here, your voice matters, and your contributions make a real impact. "Employees Number One" and "Clients Centered" are the core cultural values at Pharmaron. Our culture, which sets Pharmaron apart from other organizations, has evolved from our deep commitment to our employees, partners and collaborators.
Benefits: As part of our commitment to your well-being, we offer a comprehensive benefits package:
Insurance including Medical, Dental & Vision with significant employer contributions
Employer-funded Health Reimbursement Account
Healthcare & Dependent Care Flexible Spending Accounts
100% Employer-paid Employee Life and AD&D Insurance, Short and Long Term Disability Insurance
401k plan with generous employer match
Access to an Employee Assistance Program
How to Apply:
Ready to seize this incredible opportunity? Join us at Pharmaron and be part of a dynamic team driving innovation and excellence in biopharmaceutical research and development. Apply online today!
Pharmaron is a premier service provider for the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities and established a broad spectrum of research, development, and manufacturing service capabilities throughout the entire drug discovery, preclinical, and clinical development process across multiple therapeutic modalities, including small molecules, biologics, and CGT products. With over 21,000 employees and operations in the U.S., the U.K. and China. Pharmaron has an excellent track record in delivering R&D solutions to its partners in North America, Europe, Japan, and China.
As an Equal Employment Opportunity and Affirmative Action employer, Pharmaron values diversity and inclusion in the workplace, fostering an environment where all individuals are empowered to succeed. Join us in our mission to make a difference in the world of life sciences.
Product Development Scientist
Principal research scientist job in Ayer, MA
About Us
Eat Well, Live Well. At Ajinomoto Cambrooke, we build careers grounded in helping improve people's health through nutritional therapies.
Ajinomoto Cambrooke (ACI) was founded by parents looking to develop better solutions for their children with PKU. Over the subsequent 25 years, we have expanded into additional therapeutic areas with a focus on enjoyable nutrition as a core part of normalizing the life for people living with medical conditions.
Joining ACI means becoming part of a diverse team of talented people who want to build their careers while contributing back to society in a positive way. We seek individuals who bring an entrepreneurial mindset with a bias for action and finding solutions. We provide an environment based in mutual respect and collaboration to support you and give you opportunities to learn and develop.
Join us to find a rewarding work experience that lets you be at your best and have an impact on our patient communities.
Why Join Us
Our people are the key ingredient to our success. We offer a collaborative, innovative environment where you can grow your career and make an impact on global food and health solutions.
We provide a comprehensive and competitive total rewards package, including:
• Competitive Pay and Annual Bonus Opportunity
• 401(k) with Company Contributions
• Medical, Dental, and Vision - Effective Day 1
• Paid Time Off, Company Holidays, and Floating Holidays
• Paid Parental Leave
• Wellness Programs and Yearly Wellness Reimbursement
• Work Flexibility
• Company-Paid Life and Disability Insurance
• Employee Assistance Program (EAP)
• Tuition Reimbursement Opportunities
• Career Growth and Development within a Global Organization
• Company-Provided Mental Health and Caregiving support
Overview
The Product Development Team supports the medical nutrition business by developing new and revising existing product formulations to meet target characteristics that will deliver positive patient outcomes through therapeutic nutrition. Strong collaboration with the Directors of Medical Nutrition, Marketing, and Sales will be required to ensure desired nutritional levels are achieved throughout the product shelf-life, patient insights on flavor, texture, and palatability are incorporated. In this role, you will contribute to the ideation and exploration for uses of new to ACI ingredients and new to ACI business ventures in additional disease-states reliant on specialized medical nutrition. This position sits in our Corporate Office located in Ayer, MA.
Qualifications
EDUCATION, CERTIFICATIONS AND EXPERIENCE:
• Minimum bachelor's in food science, nutrition, or related field; Master's degree preferred. PhD, PharmD a plus.
• 5+ years of experience in product development, with ability to take concepts from bench top to commercialization for nutritional beverages and / or nutritional powder blends from concept to commercialization.
• 5+ years in basic and applied research and development preferably in small/mid-sized nutrition, food and/or biotech company. Experience with food/beverage formulation and manufacture of nutritional products that meet stability, sensory and nutritional requirements. Direct experience with aseptic processing / Tetra Pak a plus.
• Expert scientific knowledge in food science with emphasis on product development involving interaction amongst ingredients and impact of process techniques on use of micro-nutrients.
• Experience with nutritional modeling software and familiarity with FDA regulations preferred, exposure to EU regulations a plus.
• Able to design and monitor product shelf-life procedures both regular and accelerated for nutritional products.
• Strong translational science background with experience in converting basic nutrition-science insights into consumable products.
KNOWLEDGE, SKILLS AND ABILITIES:
• Build relationships with vendors to source ingredients to meet product specifications.
• Overall understanding of how business units interact to facilitate successful product development and commercialization.
• Ability to define new product needs in terms of process needs and product characteristics including organoleptic needs / claims
• Demonstrated Leadership capability with a focus on innovation to drive product development proactively and passionately.
• Exhibit the understanding of use of standard operation procedures related to product development, process development and product shelf-life determination.
• Well versed with food safety requirements and regulations.
• An understanding of human nutrition and ability to review primary scientific literature.
• A strong ability to communicate basic science and technical challenges to non-technical audiences.
• A strong understanding of ingredient interactions in a food/beverage matrix throughout processing and shelf life.
• Ability to design shelf-life evaluation matrices considering product composition, process impact and other critical factors when designing new products in medical nutrition arena.
• An understanding of macro and micro-nutrient analytical procedures and their principles.
• Ability to work in a fast paced, cross functional team environment.
• Excellent analytical skills, strong attention to details, good communication and interpersonal skills.
• Excellent organizational skills, the ability to balance multiple projects, set priorities, and drive results.
Working Conditions / Physical Requirements
WORKING CONDITIONS:
This position works in a food manufacturing environment and requires the ability to adhere to all GMP, Food Safety, workplace safety and security policies including wearing required personal protective equipment, as well hair net, beard net, etc. as required
PHYSICAL REQUIREMENTS:
Position requires the ability to occasionally lift up to 50 pounds, stand, walk, bend, reach, push, and pull.
Ability to use a computer, keyboard, telephone, and other office equipment.
Ability to wear all required PPE.
Responsibilities
• Utilize your exemplary food science and ingredient know-how to co-create and execute medical formula products against ACI's strategic R&D roadmap to support the overall corporate strategy while meeting the internal quality expectations.
• Support the Leadership and Management teams with scientific support in the areas of product development, clinical development, product manufacturing and new ingredient compound / product initiatives.
• Research and help develop clinical evidence supporting existing and new products and ingredient compounds for use in commercial activities.
• Participate in conferences, clinician meetings and other forums to present ACI's clinical evidence.
• Ensure existing and new products, processes or ingredient compounds have strong Intellectual Property protection thus providing ACI a sustained competitive advantage.
• Other duties as assigned.
Salary Range $105,000 - $130,000 Annual with potential 12.5% Bonus EEO Statement
Ajinomoto Cambrooke, Inc. is an Equal Opportunity Employer-Vets/Disabled, committed to a diverse workforce. If you need assistance with completion of an application for employment, please contact Human Resources Department at ************.
Auto-ApplyBioPharmaceutical Opportunity for a Senior Research Associate | Research Scientist: BioPhysical Chemistry
Principal research scientist job in Woburn, MA
. . . . . GROWTH OPPORTUNITY
BIOPHYSICAL CHEMISTRY | BIOCHEMISTRY
MISSION STATEMENT:
Develop BioPhysical and Biochemical Assays for screening and characterizing small molecules.
Do your skills include the following?
Biophysical methods: SPR for determining small molecule affinity to protein targets
Biochemical assays: develop, analyze and troubleshoot (e.g. FRET, FP, AlphaScreen/LISA, ADPGlo)
Protein characterization techniques: size exclusion chromatography, dynamic light scattering, DSF, TSA
If you are answering YES - - Reach out to learn more about this exciting new opportunity:
Call: ************
or
Schedule a time: ********************************
or
Email: *************************
Visit our Company Website - ************************
Visit our Career Opportunities Page - *****************************
Easy ApplySenior Research Associate / Associate Scientist
Principal research scientist job in Cambridge, MA
Nanopath is a well-funded Series A-stage company working to develop a first-in-class in vitro diagnostics platform to revolutionize the way we diagnose disease. Nanopath works to disrupt existing lengthy molecular testing methodologies by bringing them closer to the patient. We aim to improve the lives of patients, starting with women, using our purpose-built tool that provides actionable information within a single office visit.
The company is headquartered at The Engine, the premier tough technology incubator in the Kendall Square ecosystem. As a company, we are committed to health equity and the design of solutions for underserved populations and low-resource settings. Corporate sustainability - both environmental and social - is at the forefront of our decision making.
About the Role
Independently design and execute experiments for development of Nanopath's proprietary assay
Perform advanced data analysis and protocol optimization
Develop experimental protocols, lead small projects, and write technical reports
Iterate assay design through benchtop study to improve sensitivity & specificity
Characterize samples using molecular biology techniques
Culture and quantify a range of microorganisms
Present data to management team
Technical Qualifications
Experience working in a BSL-2 laboratory environment and with sterile technique
Comfortable handling & processing a range of human biofluid samples
Deep understanding of bacteriology and microorganisms
Deep understanding of molecular biology and experience with molecular biology techniques
Familiarity with bacterial culture, PCR, and basic wet laboratory techniques
Robust understanding of scientific method and experience in design-of-experiments
General Qualifications
Able to commit to full-time and onsite work in Cambridge, MA
B.S. in Biological Sciences/Engineering plus 2-3 years industry experience or M.S. in Biological Sciences/Engineering plus 1-2 years industry experience
Excellent communication and presentation skills
Highly organized with demonstrated curiosity, scientific rigor and creative problem-solving
Proactive self-starter with enthusiasm to adapt to a fast-paced, dynamic startup environment
Passion for technology translation and willingness to shape Nanopath's future
Don't meet every single requirement? Studies have shown that women and people of color are less likely to apply to jobs unless they meet every single qualification. At Nanopath we are dedicated to building a diverse and inclusive workplace, so if you're excited about this role but your past experience doesn't align perfectly with every point in the job description, we encourage you to apply anyways. You may be just the right candidate for this or other roles!
Nanopath Inc. is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.
Nanopath does not accept unsolicited resumes from recruiters or agencies and we will not be responsible for any fees related to resumes that are unsolicited. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Nanopath, and Nanopath will not owe any referral or other fees with respect thereto.
Assay Development Senior Research Associate/Associate Scientist
Principal research scientist job in Newton, MA
ABOUT US There are more than 9 million immunocompromised people in the United States. Almost half a million of those represent a population that are moderately to severely immunocompromised and at highest risk for severe COVID-19, including stem cell and solid organ transplant patients as well as those with hematologic cancers.
At Invivyd, Inc., we take those numbers very seriously and we come to work each day on a mission to deliver protection from serious viral infectious diseases, beginning with SARS-CoV-2. Invivyd deploys a proprietary integrated technology platform unique in the industry designed to assess, monitor, develop, and adapt to create best in class antibodies.
In March 2024, Invivyd received emergency use authorization (EUA) from the U.S. FDA for a monoclonal antibody (mAb) in its pipeline of innovative antibody candidates.
In October 2025, the FDA cleared the company's Investigational New Drug (IND) application and provided feedback to advance the company's REVOLUTION clinical program, Invivyd's development program for VYD2311, a vaccine alternative monoclonal antibody being investigated for the prevention of COVID-19.
Be part of making a difference. Be part of Invivyd.
Location: Newton, MA
Invivyd's lab is in Newton, MA. This role will be an in-person role.
Position Summary:
In this role you will design, develop and execute functional assays for a cutting-edge antibody discovery platform. This involves applying a breadth of techniques in the virology, molecular biology, cell biology, and immunology spaces to advance innovative biotherapeutic products through discovery and pre-clinical development stages at Invivyd. This is a unique opportunity to join Invivyd's Antibody Discovery and Preclinical Development Team which generates and characterizes human therapeutic antibody candidates against infectious disease targets like SARS-CoV-2, influenza, and RSV. The Assay Development Senior Research Associate will serve as a key member of the discovery team, provide expert input, and execute new and established methods to meet project requirements and timelines.
Responsibilities:
* Development and independent troubleshooting of virus-based antibody screening functional assays and optimization of existing assays.
* Contribute to high-impact projects within the Discovery group by characterizing lead antibody molecules for pre-clinical studies.
* Design and perform experiments involving in vitro screening and characterization of antibody drug candidates using immunological, biochemical, and cell-based assays.
* Design and generate pseudoviruses for use in evaluation of antibody candidates.
* Generate authentic viruses in a BSL-2 setting for use in evaluation of antibody candidates.
* Perform molecular design and characterization of DNA constructs used for assay development.
* Execute basic molecular biology (DNA/RNA extraction, RT-PCR, PCR, cloning, etc.) and Cell Biology (mammalian cell culture, gene transfection and expression) to support antibody discovery efforts.
* Collaborate closely across an interdisciplinary biologics research team to drive antibody discovery campaigns.
* Employ high-throughput molecular biology methods for building new vectors and libraries.
* Maintain appropriate records e.g. lab notebook, protocols, reports, data integrity.
* Present data, both orally and as written reports, to internal stakeholders.
Requirements:
* Master's degree or Bachelor's degree and 6+ years of bench Industry experience in virology, molecular biology, cell biology, or other life science disciplines.
* High proficiency in mammalian cell culture is required.
* Previous experience working with virus in a BSL-2 setting is required.
* Previous experience designing and optimizing cell-based assays and functional antibody characterization is highly preferred.
* Ability to interpret in-process readouts for the purposes of assay optimization and troubleshooting.
* Mammalian cell transfection with an understanding of expression vector design is highly preferred.
* Strong understanding of molecular biology and experience with DNA construct design and sequence analysis is highly preferred.
* Proactive team player and flexibility to work on multiple projects as the discovery programs evolve over time.
* Excellent verbal and written technical and non-technical communication skills.
At Invivyd we strive to create a welcoming and inclusive environment. Here all applicants will receive equal consideration for employment without discrimination on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other applicable legally protected characteristics.
Invivyd is proud to be an equal opportunity employer.
We do not accept unsolicited resumes from agencies.
Auto-ApplyMachine Learning Scientist, AI Explainability
Principal research scientist job in Woburn, MA
About Us:
SES AI Corp. (NYSE: SES) is dedicated to accelerating the world's energy transition through groundbreaking material discovery and advanced battery management. We are at the forefront of revolutionizing battery creation, pioneering the integration of cutting-edge machine learning into our research and development. Our AI-enhanced, high-energy-density and high-power-density Li-Metal and Li-ion batteries are unique; they are the first in the world to utilize electrolyte materials discovered by AI. This powerful combination of "AI for science" and material engineering enables batteries that can be used across various applications, including transportation (land and air), energy storage, robotics, and drones.
To learn more about us, please visit: **********
What We Offer:
A highly competitive salary and robust benefits package, including comprehensive health coverage and an attractive equity/stock options program within our NYSE-listed company.
The opportunity to contribute directly to a meaningful scientific project-accelerating the global energy transition-with a clear and broad public impact.
Work in a dynamic, collaborative, and innovative environment at the intersection of AI and material science, driving the next generation of battery technology.
Significant opportunities for professional growth and career development as you work alongside leading experts in AI, R&D, and engineering.
Access to state-of-the-art facilities and proprietary technologies are used to discover and deploy AI-enhanced battery solutions.
What we Need:
The SES AI Prometheus team (AI Research) is seeking an exceptional Machine Learning Scientist to spearhead the development of our Large Language Models (LLM) and advanced AI agents. This role is pivotal in enabling groundbreaking research in machine learning for scientific discovery, particularly in the realm of material science and battery technology.
Harness internal expertise and collaborate with external research labs to advance scientific ML.
Work will be incorporated directly into our groundbreaking Deep Space multi-agent system for battery technology discovery.
This position can be remote.
Essential Duties and Responsibilities:
Research & Development
Lead cutting-edge research in machine learning for scientific discovery, with a focus on (multimodal) Large Language Models and their application (including AI agents) in battery and material discovery.
Conduct groundbreaking research on integrating domain-specific data (including literature and internal documents) into LLM training and inference.
Investigate the mechanisms through which LLMs approach problem-solving, planning, and solution generation, particularly in the context of basic battery design questions.
Model Optimization & Implementation
Troubleshoot and optimize the training process of large language models, addressing complexities and challenges related to data quality, model architecture, and computational efficiency.
Implement innovative solutions to enhance model performance and scalability.
Collaborate closely with a multidisciplinary team to integrate findings into practical AI solutions that contribute to the discovery of new battery materials and the advancement of lithium battery technology.
Collaboration & Communication
Contribute to academic and industry discussions by publishing research findings in top-tier journals and presenting at conferences.
Engage in machine learning research aimed at addressing battery design challenges and enhancing system ability to interpret data-driven science efficiently.
The ability to communicate complex concepts clearly and effectively to both technical and non-technical team members.
Education and/or Experience:
MS or PhD in Computer Science, Statistics, Computational Neuroscience, Cognitive Science or a related field, or equivalent practical experience.
Strong foundational knowledge and practical experience in Machine Learning, Deep Learning, and Large Language Models.
Proficiency in programming languages relevant to machine learning, with a strong preference for Python.
Experience with deep learning frameworks such as PyTorch or TensorFlow.
Proficiency in utilizing causal graphs for AI research and application.
A solid track record of innovative research, preferably with published work in relevant areas.
Excellent problem-solving abilities and a passion for tackling complex technical challenges.
Preferred Qualifications:
Experience with AI applications in material science or battery technology.
Familiarity with the latest trends and methodologies in AI research, including algorithms such as GRPO.
Auto-ApplyScientist - Mass Spectrometry
Principal research scientist job in Boston, MA
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
At Lilly, we serve an extraordinary purpose. We make a difference for people around the globe by discovering, developing, and delivering medicines that help them live longer, healthier, more active lives. Not only do we deliver breakthrough medications, but you also can count on us to develop creative solutions to support communities through philanthropy and volunteerism.
The LIGM RNA Group is seeking an experienced analytical scientist with extensive hands-on experience in analytical techniques for characterizing and analyzing small molecules, biologics, and/or oligonucleotides. The ideal candidate will have a proven track record in analytical method development and troubleshooting, as well as experience with liquid chromatography, (high resolution) mass spectrometry, and other advanced analytical techniques.
They must possess strong technical problem-solving skills, be computer savvy with the ability to navigate multiple instrument control programs and data analysis environments, and be able to work independently to achieve efficient, quality results in a fast-paced environment.
Responsibilities:
Work closely with the chemistry team to source, explore, and implement the latest separation science and analytical technologies for the purification and characterization of oligonucleotides and their conjugates, including carbohydrates, lipids, peptides, and proteins.
Conduct LC and LC-MS based method development for sensitive characterization of biologics including intact mass, reduced mass, peptide mapping, and glycan mapping to provide better understanding of attributes.
Conduct semi-preparative and preparative method development activities to advance downstream processing for challenging modified oligonucleotides, utilizing RP purification, ion-exchange chromatography, spin filtration, TFF, FPLC, size exclusion chromatography, and MS-direct auto-scale preparative LC-MS techniques.
Work with contractors and third-party vendors to troubleshoot and maintain lab instruments, including but not limited to UPLC, LC-MS, osmometer, and NanoDrop, ensuring they remain in peak operational condition.
Learn new technologies quickly and apply effective scientific concepts and methods across multiple areas.
Process and present data leveraging Microsoft Office apps, GraphPad and Spotfire for data organization and data visualization.
Document experiments, data, technical reports, and findings electronically in an accessible manner with good documentation practices.
Present findings, progress, and data proactively and regularly in group and department meetings.
Possess a collaborative and willing-to-share mindset with excellent verbal and written communication skills, presentation skills, and attention to detail.
Ability to follow Global Health, Safety & Environment Center (HSE) guidelines while performing tasks.
Basic Qualifications:
Bachelor's or Master's degree in Analytical Chemistry, Biochemistry, Chemistry, Food Science, or a related scientific field, with over 2 years of relevant post-graduate experience in industry.
Additional Skills/Preferences:
Strong analytical thinking skills with a demonstrated ability to articulate issues and extract and synthesize complex information into key focus areas.
Extensive experience in operating and troubleshooting a range of mass spectrometers including Q-ToF, QQQ and Orbitrap
Proficient with Thermo XCalibur, Agilent ChemStation and MassHunter software.
Understanding tandem mass spectrometry and interpretation of MS/MS based characterization of including but not limited to peptide, peptide-oligonucleotide conjugates, and lipid conjugates.
Extensive hands-on experience in downstream workflows for small molecules, biologics, and oligonucleotides. Experience with antibody-drug-conjugates (ADCs) or antibody-oligonucleotide-conjugates (AOCs) is a plus.
Proven expertise in liquid chromatography including ion-pair reverse phase liquid chromatography as well as ion chromatography.
Prior experience in native mass spectrometry and understanding of electrospray ionization as well as molecular behavior in the gas phase.
Prior experience in proteomics, bioanalysis, and/or CMC is a significant advantage.
Highly self-motivated and self-driven attitude with ability to own and drive projects into success.
Strong organizational and communication skills and effective people skills.
Capable of continuous learning, open-minded, highly organized, and detail oriented.
Ability to balance multiple activities, prioritize and handle ambiguity.
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (******************************************************** for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.
Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), en Able (for people with disabilities). Learn more about all of our groups.
Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is
$71,250 - $187,000
Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
#WeAreLilly
Auto-ApplySenior Bioinformatics Scientist - Transcriptomics
Principal research scientist job in Boston, MA
About Somite
Somite.ai is a venture-backed company aiming to become the OpenAI of stem cell biology, developing AI foundation models for human stem cells to drive novel cell therapies at scale.
We take a full-stack approach - generating data at 1,000x lower cost, training large-scale models with unmatched predictive power, and using these models to discover, refine, and optimize high-impact applications in cell therapy.
Our founding team includes repeat AI entrepreneur Dr. Micha Breakstone (Chorus.ai, acquired for $575M), the Head of the Fundamental AI Group at MIT (pioneered the foundational research on scaling laws), and three Harvard Medical School professors and National Academy of Sciences/Medicine members, including the Chair of the Genetics Department at HMS. Based in Boston and launching operations in January 2024, Somite has raised close to $60M to date (Forbes).
Somite's Core Values:
We show up - fully accountable, all-in, doing whatever it takes
We act with urgency - swift, decisive, proactive
We support one another - collaborative, helpful, empathetic
Location:
Boston, MA (onsite, full-time)
About the Role:
We seek a skilled Bioinformatician to lead the design and execution of analysis pipelines for large-scale transcriptomic datasets. You'll be responsible for preprocessing, quality control, and biological interpretation of sequencing data, contributing to the development of novel sequencing protocols and technologies in close collaboration with wet lab scientists, computational biologists and machine learning researchers to support Somite's therapeutic programs.
This is a hands-on, data-centric role ideal for someone who thrives in a fast-paced, interdisciplinary environment and wants to help build transformative cell therapy technologies from the ground up.
Responsibilities:
Build, maintain, and run robust, reproducible pipelines for single-cell and bulk RNA-seq data (QC, alignment, quantification, normalization, clustering, annotation, etc.).
Apply standard and advanced analyses using tools like Scanpy, Seurat, and R/Bioconductor packages.
Process and interpret data from state-of-the-art single-cell transcriptomic and multiomic platforms, alongside new in-house protocols being developed to enable innovative microbiological sequencing workflows.
Collaborate with wet lab scientists to support experimental design and data interpretation.
Mentor and foster collaboration and knowledge sharing across disciplines.
Help design and validate cutting-edge protocols for novel transcriptomic technologies, integrating new experimental modalities with bioinformatics pipeline.
Qualifications:
PhD in Bioinformatics, Genomics, Computational Biology, or a related field. Equivalent industry experience is also welcome
3+ years of hands-on experience analyzing large-scale single-cell or bulk transcriptomic datasets
Proficiency with common genomics tools: SAMtools, STAR/STARsolo, Bowtie, Tophat, HTSeq, Clustal, bash scripting, etc.
Strong command of Scanpy or Seurat
Demonstrated fluency in Nextflow/Snakemake and workflow reproducibility principles.
Strong R and/or Python programming skills
Excellent organizational and documentation habits
Preferred Qualifications:
Experience working in a quantitative lab or with biotech/pharma pipelines
Experience working in a fast-paced startup or interdisciplinary team
The opportunity to contribute to platform technologies with real-world therapeutic impact
Experience working at the interface of technology development and data analysis, particularly involving novel molecular biology or sequencing techniques
What We Offer
A mission-driven team reshaping healthcare through innovation in AI and cellular engineering
The opportunity to contribute to platform technologies with real-world therapeutic impact
Competitive compensation and equity in a high-growth company
Flexible work arrangements, generous benefits, and a collaborative environment
Exceptional candidates who demonstrate outstanding capabilities and potential will be considered, even if they do not meet every qualification listed.
Join us and help unlock the full potential of AI for the benefit of human health!
Somite is committed to equal employment opportunity and non-discrimination for all employees and applicants regardless of race, color, ancestry, sex, sexual orientation, age, religion, national origin, ancestry, genetic information, disability, veteran status, marital status, citizenship status, or any characteristic protected under applicable law.
Auto-ApplyBehavior Scientist
Principal research scientist job in Lawrence, MA
Established in 1980, the Greater Lawrence Family Health Center, Inc. (GLFHC) is a multi-site, mission-driven, non-profit organization employing over 700 staff whose primary focus is providing the highest quality patient care to a culturally diverse population throughout the Merrimack Valley. Nationally recognized as a leader in community medicine (family practice, pediatrics, internal medicine, and geriatrics), GLFHC has clinical sites in Lawrence, Methuen, and Haverhill and is the sponsoring organization for the Lawrence Family Medicine Residency program.
About Lawrence Family Medicine Residency Program: GLFHC was the first federally-qualified community health center in the United States to host a teaching residency program. Started in 1994, the Lawrence Family Medicine Residency is accredited through GLFHC and is affiliated with Lawrence General Hospital. From 1994 through 2021, LFMR has 210 physician graduates.
While most family medicine residencyâ¯programsâ¯are three years in length,â¯LFMR is a four-year training programâ¯that is part of a national pilot looking at training innovation. Residents spend an extra year of training toâ¯further expand their scope of practice, particularly in an area of concentration,â¯and to develop further expertise in population health, health systems management and leadership,â¯and integrating that care into communities. Resident physicians also participate in a nationally recognized curriculum where they learn to speak and provide medical care in Spanish. The goal of the training program is to train family physicians who provide comprehensive primary care to vulnerable populations and can improve the health and health equity of these communities.â¯â¯
GLFHC is currently seeking a Behavior Scientist. The Behavior Scientist teaches family residents on an individual basis, in group settings including didactic lectures, workshops, and seminars on behavioral science topics. Assists in the development and implementation of a family medicine behavioral science curriculum and professional development activities for family medicine residents. Provides residents with skills needed to maintain their commitment to practicing high quality patient-focused care within a high stress work environment. Ensures compliance with ACGME behavioral science/professional development requirements for family medicine residents. Provides residents with the tools necessary to develop the skills needed to work effectively with underserved and multi-ethnic populations. Provides clinical services in the outpatient setting inclusive of diagnostic and crisis assessment, psychological education and intervention, individual and systematic interventions and health and behavior coaching.
Qualifications
Experience with Family Medicine residency medical education.
Experience in providing integrated care with a team of physicians and a track record of working with teams of health care providers and support staff from different disciplines.
Experience providing psychotherapy to a socioeconomically challenged and ethnically underprivileged community
Interest in conducting research consistent with the complexity of issues that arise in primary care and the delivery of integrated care and associated curricular development.
Massachusetts state license.
Expertise with motivational interviewing and cognitive behavioral therapy techniques.
Bilingual in Spanish preferred (faculty development in Spanish language learning is available)
Education
Ph.D. or Psy.D. in Psychology, or LICSW with expertise in individual and family therapy.
GLFHC offers a setting that's flexible, rewarding and challenging. If you want to make an impact to the community we serve, apply today!
Bioinformatician II
Principal research scientist job in Boston, MA
The Center for Cancer Genomics (CCG) at Dana-Farber Cancer Institute facilitates genomic discoveries in cancer using novel technology platforms to assist researchers in both genome-wide and gene-focused efforts. Technologies are selected and developed with a view to research-oriented ventures, as well as translational medicine and clinical relevance. Our clinical and research environments currently use state-of-the-art massively parallel sequencing assays of DNA and RNA from patient tumor samples. Data from these environments are used to advance research on both adult and pediatric cancers, improve our understanding of cancer biology, and advance the field of precision cancer medicine. This opportunity offers the chance to work at the forefront of translational cancer technologies and applications, in an informatics group that enables analyses in both arenas.
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
Responsibilities
The Bioinformatician II will report to CCG's Lead Informaticist and have the main responsibility of independently performing data analysis on a wide array of cancer multiomics projects (sc/sn RNAseq, sc ATACseq, Crispr screens, SNV/CNV, longread Oxford Nanopore Direct RNA sequencing, etc.) in consultation and collaboration with internal Dana-Farber research collaborators and external research partners. Some limited orchestration of automated pipelines may be required as necessary. The Bioinformatician II will have no direct reports. Dana-Farber has a wealth of local, on-premises, and cloud-based computing resources available to extensively explore the large body of data generated annually by Dana-Farber researchers and collaborators. Given these resources, the development of novel computational methods is strongly encouraged.
Qualifications
MINIMUM JOB QUALIFICATIONS:
Minimum Education: Bachelor's degree required in a STEM field. Master's degree or PhD strongly preferred in bioinformatics, medical informatics, computational biology, statistics, computer science/engineering, or a related quantitative field.
Minimum Education: 3 Years of experience required; Master's degree with 1 year experience required; PhD with 0 years.
* Experience with bioinformatics tools and databases for sequence alignment/analysis; germline and somatic variant calling; bulk and single-cell/nuclei RNAseq; long read sequencing (Oxford Nanopore).
* Proficiency in programming languages commonly used in bioinformatics and data analysis, such as Python, R, and Perl. Experience with workflow languages such as WDL or Nextflow is a plus.
* Excellent communication skills and ability to work collaboratively in multi-disciplinary team.
Pay Transparency Statement
The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications.
For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA)
$83,800 - $90,800
At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.
EEOC Poster
Auto-ApplyBioinformatician
Principal research scientist job in Boston, MA
About the Opportunity
The Bioinformatician will report to Ayan Paul, Research Scientist at EAI, and collaborate with Scientists and Clinicians from Peter Castaldi's group at the Harvard Medical School, John Platig's Network Biology group at the University of Virginia, and Jennifer Dy's group at ECE, Northeastern University. Responsibilities will include building an ETL pipeline for ENCODE genomics data, writing Python code for data analysis, and a downstream R pipeline for post-processing data using standard Bioinformatics libraries from Bioconductor. There will be opportunities to participate in building machine learning models, co-author publications, and contribute to grant proposals. Tentative start date: January 2024 for the Spring 2024 semester with possibilities of renewal. This work will contribute towards the understanding of genetic origins of complex diseases like Chronic Obstructive Pulmonary Disease and cutting-edge machine learning-based methodologies for regulation of mRNA splicing.
RESPONSIBILITIES INCLUDE:
Building ETL pipelines for genomics/transcriptomics data from public databases and processing them with publicly available codes in python and R.
Documenting the entire process and all the codes generated and maintaining structured and regular commits in a GitHub repository.
Helped implement machine learning models and automate the processing of input data.
Write reports/prepare slide decks describing work performed.
Contribute to scientific manuscripts and grant proposals where appropriate.
MINIMUM QUALIFICATIONS:
A Master's degree (or equivalent)
A minimum of 3-4 years of experience working with data pipelines and data analysis.
Proficiency in Python and R. Experience working in Unix OS and remote computing clusters.
Have demonstrable expertise in bioinformatics, especially genomics, transcriptomics, proteomics and/or metabolomics, and have a good grasp of statistics.
Experience working with genomics databases like ENCODE and familiarity with RNA-seq, eCLIP, and other data is highly desirable but not required.
An ability to write clean and well-documented code and work with GitHub repositories.
Position Type
Temporary
Additional Information
Northeastern University considers factors such as candidate work experience, education and skills when extending an offer.
Northeastern has a comprehensive benefits package for benefit eligible employees. This includes medical, vision, dental, paid time off, tuition assistance, wellness & life, retirement- as well as commuting & transportation. Visit ************************************* for more information.
All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, religion, color, national origin, age, sex, sexual orientation, disability status, or any other characteristic protected by applicable law.
Pay Rate:
$45/hour
Auto-ApplySenior Research Scientist - Computational Wind Engineering
Principal research scientist job in Norwood, MA
Established nearly two centuries ago, FM is a leading mutual insurance company whose capital, scientific research capability and engineering expertise are solely dedicated to property risk management and the resilience of its policyholder-owners. These owners, who share the belief that the majority of property loss is preventable, represent many of the world's largest organizations, including one of every four Fortune 500 companies. They work with FM to better understand the hazards that can impact their business continuity to make cost-effective risk management decisions, combining property loss prevention with insurance protection.
Join a world-class research team dedicated to reducing the impact of natural hazards and climate risks. FM is a market leader in commercial and industrial property insurance and loss prevention, serving over one-third of FORTUNE 1000 companies with engineering-based risk management and property insurance solutions. FM helps clients maintain business continuity through state-of-the-art engineering and research.
The Structures and Geohazards Research Group at FM is seeking a creative and self-motivated Senior Research Scientist with a strong foundation in wind engineering and a specialized focus on computational wind engineering (CWE). The ideal candidate will possess deep expertise in fluid dynamics, high-performance computing, and wind tunnel testing, along with a demonstrated ability to conduct innovative, high-impact research.
This role is integral to a strategic research initiative aimed at advancing the understanding of wind-related hazards and developing effective mitigation strategies. The successful candidate will contribute to cutting-edge projects that blend computational modeling with experimental validation to address real-world challenges in wind engineering.
Responsibilities:
Develop computational fluid dynamics (CFD) models to simulate wind flow around buildings and infrastructure, capturing complex aerodynamic interactions.
Analyze wind loading on structures using high-resolution simulations; validate results with wind tunnel experiments or field measurements.
Collaborate with interdisciplinary teams to incorporate wind effects into risk models, design standards, and resilience strategies.
Publish and present research in peer-reviewed journals and at scientific or industry conferences.
Contribute to strategic planning and innovation in wind engineering research initiatives.
PhD degree. Mechanical, Civil, Aerospace Engineering or related fields.
Hands-on experience with CFD software, both open-source (e.g., OpenFOAM) and commercial (e.g., ANSYS Fluent).
Proficient in programming languages such as C++, Python, R, MATLAB.
Skilled in high-performance computing (HPC) and parallel computing environments.
Experience with wind tunnel testing or field measurements is highly desirable.
Familiarity with relevant building codes and standards is a plus.
Proven track record of publishing high-quality research and effectively communicating complex technical concepts to diverse audiences.Strong problem-solving abilities, creativity, and the capacity to work independently as well as collaboratively.
The final salary offer will vary based on geographic location, individual education, skills, and experience. The position is eligible to participate in FM's comprehensive Total Rewards program that includes an incentive plan, generous health and well-being programs, a 401(k) and pension plan, career development opportunities, tuition reimbursement, flexible work, time off allowances and much more.
FM is an Equal Opportunity Employer and is committed to attracting, developing, and retaining a diverse workforce.
Auto-ApplySenior Research Associate / Associate Scientist
Principal research scientist job in Cambridge, MA
Nanopath is a well-funded Series A-stage company working to develop a first-in-class in vitro diagnostics platform to revolutionize the way we diagnose disease. Nanopath works to disrupt existing lengthy molecular testing methodologies by bringing them closer to the patient. We aim to improve the lives of patients, starting with women, using our purpose-built tool that provides actionable information within a single office visit.
The company is headquartered at The Engine, the premier tough technology incubator in the Kendall Square ecosystem. As a company, we are committed to health equity and the design of solutions for underserved populations and low-resource settings. Corporate sustainability - both environmental and social - is at the forefront of our decision making.
About the Role
Independently design and execute experiments for development of Nanopath's proprietary assay
Perform advanced data analysis and protocol optimization
Develop experimental protocols, lead small projects, and write technical reports
Iterate assay design through benchtop study to improve sensitivity & specificity
Characterize samples using molecular biology techniques
Culture and quantify a range of microorganisms
Present data to management team
Technical Qualifications
Experience working in a BSL-2 laboratory environment and with sterile technique
Comfortable handling & processing a range of human biofluid samples
Deep understanding of bacteriology and microorganisms
Deep understanding of molecular biology and experience with molecular biology techniques
Familiarity with bacterial culture, PCR, and basic wet laboratory techniques
Robust understanding of scientific method and experience in design-of-experiments
General Qualifications
Able to commit to full-time and onsite work in Cambridge, MA
B.S. in Biological Sciences/Engineering plus 2-3 years industry experience or M.S. in Biological Sciences/Engineering plus 1-2 years industry experience
Excellent communication and presentation skills
Highly organized with demonstrated curiosity, scientific rigor and creative problem-solving
Proactive self-starter with enthusiasm to adapt to a fast-paced, dynamic startup environment
Passion for technology translation and willingness to shape Nanopath's future
Don't meet every single requirement? Studies have shown that women and people of color are less likely to apply to jobs unless they meet every single qualification. At Nanopath we are dedicated to building a diverse and inclusive workplace, so if you're excited about this role but your past experience doesn't align perfectly with every point in the job description, we encourage you to apply anyways. You may be just the right candidate for this or other roles!
Nanopath Inc. is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.
Nanopath does not accept unsolicited resumes from recruiters or agencies and we will not be responsible for any fees related to resumes that are unsolicited. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Nanopath, and Nanopath will not owe any referral or other fees with respect thereto.
Auto-ApplyBioinformatician II
Principal research scientist job in Boston, MA
The **Center for Cancer Genomics** **(CCG)** at Dana-Farber Cancer Institute facilitates genomic discoveries in cancer using novel technology platforms to assist researchers in both genome-wide and gene-focused efforts. Technologies are selected and developed with a view to research-oriented ventures, as well as translational medicine and clinical relevance. Our clinical and research environments currently use state-of-the-art massively parallel sequencing assays of DNA and RNA from patient tumor samples. Data from these environments are used to advance research on both adult and pediatric cancers, improve our understanding of cancer biology, and advance the field of precision cancer medicine. This opportunity offers the chance to work at the forefront of translational cancer technologies and applications, in an informatics group that enables analyses in both arenas.
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
The **Bioinformatician II** will report to CCG's Lead Informaticist and have the main responsibility of independently performing data analysis on a wide array of cancer multiomics projects ( _sc/sn RNAseq, sc ATACseq, Crispr screens, SNV/CNV, longread Oxford Nanopore Direct RNA sequencing,_ etc.) in consultation and collaboration with internal Dana-Farber research collaborators and external research partners. Some limited orchestration of automated pipelines may be required as necessary. The Bioinformatician II will have no direct reports. Dana-Farber has a wealth of local, on-premises, and cloud-based computing resources available to extensively explore the large body of data generated annually by Dana-Farber researchers and collaborators. Given these resources, the development of novel computational methods is strongly encouraged.
**MINIMUM JOB QUALIFICATIONS:**
Minimum Education:
Bachelor's degree required in a STEM field. Master's degree or PhD strongly preferred in bioinformatics, medical informatics, computational biology, statistics, computer science/engineering, or a related quantitative field.
Minimum Education:
3 Years of experience required; Master's degree with 1 year experience required; PhD with 0 years.
+ Experience with bioinformatics tools and databases for sequence alignment/analysis; germline and somatic variant calling; bulk and single-cell/nuclei RNAseq; long read sequencing (Oxford Nanopore).
+ Proficiency in programming languages commonly used in bioinformatics and data analysis, such as Python, R, and Perl. Experience with workflow languages such as WDL or Nextflow is a plus.
+ Excellent communication skills and ability to work collaboratively in multi-disciplinary team.
**Pay Transparency Statement**
The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications.
For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA)
$83,800 - $90,800
At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.
**EEOC Poster**