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  • Associate Scientist in Formulation Group

    At Horizon Therapeutics, we define success by the number of lives touched, lives changed, and lives saved. Horizon Therapeutics is searching for a highly motivated individual to be part of a team responsible for the development of biopharmaceutical formulations and drug product manufacturing processes.
    $55k-81k yearly est.10d ago
  • Associate Scientist, Histotechnology/ LCM

    We are seeking an enthusiastic and experienced Associate Scientist within the MDPL to support all aspects of assay development for laser microdissection and other spatial biomarker assays. Facility: Rockville: 9615 MedCtrDr Location: 9615 Medical Center Drive, Rockville, MD 20850 USA The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc.
    $63k-93k yearly est.15d ago
  • Signal and Info Processing Research Scientist

    Job Description Job description: The position responsibilities include data analysis, signal and clutter phenomenology identification/capture/modeling, and advanced algorithm development, implementation and testing. The position responsibilities include data analysis, signal and clutter phenomenology identification/capture/modeling, and advanced algorithm development, implementation and testing.
    $53k-80k yearly est.34d ago
  • Scientist, Analytical R&D

    Job DescriptionDescription: **Flex on level of position based on experience** JOB SUMMARY: * Testing the product development samples and supporting R&D team on timely manner with analytical sample testing * Performing the Assay, Dissolution analytical method development and method validation. * Testing and release of in-process finished product and Stability samples including process evaluation samples. * Prepare the analytical method validation / verification protocols * Follows standard operating procedures to complete tasks. * Responsible for the safe and efficient execution of job duties * JOB DUTIES & RESPONSIBILITIES * Proficient in operating the laboratory instrumentation/equipment, including but not limited to: FTIR, HPLC, UPLC, Dissolution apparatus, ICP-MS, GC, UV-Vis, Karl fisher (KF), Ion chromatography (IC), Malvern Master sizer, etc * Support the R&D team by testing the process development sample for content uniformity, blend uniformity, Assay, particle size distribution, density, water determination by KF, viscosity, and other tests as required. * Conduct analytical method development, method optimization, method validation, method verification and method transfer for finish products. * Draft test methods, method validation protocols and reports as per the Company SOPs and regulatory guidelines * Perform additional analytical testing (multimedia dissolution, photo stability, Dose dumping etc.) for ANDA submission. * Timely execution and completion of assigned tasks. * Document experiments accurately and complete all associated documents (Instrument, Standard and Column usage logbooks) in compliance with internal SOPs and FDA guidelines. * Maintain work area and laboratory with good housekeeping practices and in compliant with cGMP. * Identify and communicate continuous improvement opportunities to the Analytical manager and Director. * Monitor and ensure availability of chemicals, columns, standards, and other consumable for sample testing. * Other duties assigned by management based on requirements. MANAGEMENT RESPONSIBILITY: * Assign daily work schedule in timely manner. * Provide Guidance in method Development and validation. * Interpret and review generated results. * Provide assistance in professional development. Requirements: Minimum Experience & Education * Bachelors/master's degree in Pharmaceutical Chemistry, Analytical Chemistry or Pharmaceutical Sciences with * At least 2 or more years of relevant working experience in pharmaceutical industry chemistry or related scientific field * Knowledge of Good Manufacturing Practices (cGMP) * Experience with software and information systems (e.g. Empower, Microsoft word and Excel) Required Knowledge & Skills * Proven Knowledge of the major analytical techniques and operation of instruments such as HPLC, GC, dissolution, FT-IR, UV-VIS Spectrophotometer, Particle size analysis (Malvern Mastersizer, Sonic sifting and Sieve shaker), Karl Fisher Instrument, Potentiometric Titration, Density meter, pH meter, Melting point apparatus, Analytical Balances, Viscometer * proficient in documentation as per Good Documentation Practice * Computer skills including Microsoft and Excel * Excellent verbal and written communication and skills Physical Requirements/Working Environment * Must be able to stand for long periods of time (up to 12-hour shifts), maneuver at least 40 pounds, wear a respirator and pass associated respirator tests and/or requirements, and be able to wear all required PPE. * Vision - ability to see details at close range (within a few feet of the observer).
    $74k-105k yearly est.19d ago
  • Scientist II, Research

    At Horizon Therapeutics, we define success by the number of lives touched, lives changed, and lives saved.
    $53k-80k yearly est.22d ago
  • Bioanalytical Scientist, LC-MS/MS

    We are seeking an experienced Bioanalytical Scientist to join our LC-MS/MS team in Germantown, MD ! As a Bioanalytical Scientist , you will be responsible for performing the bioanalysis of small molecules.
    $73k-109k yearly est.32d ago
  • Research Scientist I/Research Scientist II for Indigenous Populations

    At Child Trends, we offer you a national platform, a workplace that uses teamwork to concentrate your time on your strengths, and the opportunity to co-create and build our portfolio of work focused on Indigenous children, youth, and families. Child Trends seeks a Research Scientist I or Scientist II focused on the well-being of children, youth, and families Indigenous to the lands presently known as the United States. The Research Scientist I/Scientist II will also collaborate with colleagues across Child Trends to develop and write funding proposals. Child Trends staff bring a multi-disciplinary perspective to our research and evaluation focused on children, youth, and families and the programs, systems, and policies that impact them. Qualifications Below are the required and preferred qualifications for the Research Scientist I/Scientist II for Indigenous Populations position. The Research Scientist I/Scientist II for Indigenous Populations will actively plan and execute major research, evaluation, and training and technical assistance projects in partnership with Indigenous Tribal Nations, communities, and organizations in the U.S.
    $81k-131k yearly est.10d ago
  • Image Scientist

    SJ is looking for a motivated Image Scientist to provide imagery science expertise supporting product quality and utility assessments of data collected with commercial imaging sensor constellations. Description Inc Magazine, Best Places to Work Award Winner- SJ Technologies is headquartered in Sugar Hill, Georgia, with multiple offices & remote team members across the US. Job: Image Scientist - Commercial Imagery The Image Scientist should have a working knowledge of and experience with commercial imaging sensors to include:
    $55k-86k yearly est.9d ago
  • Senior Scientist, Molecular Analytics

    We are urgently hiring qualified candidates that possess leadership, collaborative, and team-oriented skills to help in developing the in-process analytic panel for pipeline projects and next-generation cell line engineering efforts. This is a well established company looking to secure the ideal candidate to not only tick the boxes for this role, but to help grow with the company in the future! Not only will you be a part of the foundation of this growing department, but you will be involved in groundbreaking research within the emerging vaccines space! Responsibilities : Acting as a liaison between the discovery/antigen design department and the CMC organization to facilitate early on-boarding and adoption of in-process analytics based on QbD principles to promote lead antigen selection. Serving as the subject matter expert (SME) to create and execute a fit-for-purpose in-process analytic panel (Content, Potency, and Process- and Product-Related Impurities) to assist the early development of therapeutic substances for CMC, including cell line and baseline platform process development (upstream focused) developing and implementing cutting-edge nucleic acid- and next-generation sequencing-based techniques to facilitate early characterization of cell line genetic stability and next-generation cell line engineering in my capacity as the genetic analytics expert Qualifications: B.S, M.S., or PhD with at least 2-7+ years of molecular analytical development 2-year experiences with immuno analytics, e.g. ELISA, Octet and Luminex for complex protein/viral based drug substance characterization (required) Proven expertise with QbD and the ability to design a fit-for-purpose high throughput in process analytics panel to support cell line generation and cell line engineering efforts for protein/viral based biological therapeutic substance discovery in an industrial setting Deep understanding of protein engineering and structural biology. Ability to meticulously organize, carry out, and analyze experiments and data A strong scientific approach, critical thinking, and problem-solving abilities High throughput technology expertise is advantageous (eg. Liquid Handling systems such TECAN). strong oral and written communication abilities with the capacity to communicate scientific ideas across diverse functions (as demonstrated by peer-reviewed publication, patent and conference proceedings) Benefits: Healthcare Benefits Competitive 401K match ...more If you are interested in the position and others within this organization, then don't hesitate to apply or reach out to learn more!
    $86k-117k yearly est.10d ago
  • Immunology Senior Scientist

    Responsibilities: • To perform and oversee the performance of molecular and immunology assays in the laboratory, including, but not limited to, flow cytometry-based assays (surface and intra-cellular staining), handling and processing of a variety of preclinical and clinical samples, T- and B-cell ELISPOT, proliferation studies, cell and viral culture, viral neutralization assays, ELISA-based assays, biomarker detection in a multiplexed manner (Luminex, MSD), antibody affinity (ForteBio Octet), Fc function assays, tetramer analysis, qPCR and dd PCR-based molecular assays.To contribute to organizing and participating in the performance of daily scientific duties in the laboratory in order to meet commercial and government contract obligations in a timely manner. • To serve, as required, as the Scientific Lead on commercial and/or government contracts/task orders/studies and provide expertise on scientific/technical elements of the respective contract(s). Job Requirements: • PhD in Immunology, molecular biology, virology, or related discipline, with at least 2 years of post-doctoral experience developing vaccines, immuno-therapies, gene/cell therapies in preclinical/clinical phases of development. • Excellent communications skills, o Cellular Immunology assays including proliferation & cell death assays, cytotoxicity assays, etc., T cell and B cell ELISpots etc. o Flow cytometry and related assays: Immunophenotyping, intracellular staining, MLR assays etc. o NASBA assays applied to nucleic acid extraction, qPCR and digital PCR. o Virological assays such as antibody neutralizing assays, plaque assays, etc. o Antibody responses characterization: binding and functional assays and profiling soluble biomarkers / cytokines in a multiplexed fashion.
    $111k-150k yearly est.8d ago
  • Associate Scientist

    As an Associate Scientist in Bioprocess Technology and Engineering (BTE), you would join a team developing harvest operation. Industry related experience Associate Scientist I (BS with 0-5 years, MS 0-3 years).
    $61k-88k yearly est.8d ago
  • Associate Scientist/Scientist - Real World Evidence

    As part of the OPEN Health E&A team, you'll be responsible for the following activities: Able to forge and manage significant relationships within OPEN Health and with external stakeholders As a global organization, OPEN Health is committed to supporting our employees and their families through a comprehensive benefits program OPEN Health brings together deep scientific knowledge, global understanding, and broad specialist expertise to support our clients in improving health outcomes and patient wellbeing.
    $69k-94k yearly est.5d ago
  • Research Scientist

    Parsons is seeking a Research Scientist I to join our team.
    $114k-157k yearly est.5d ago
  • Senior Scientist - MSAT

    BioTalent are working with a global pharmaceutical company to search for a Senior Scientist supporting Tech Transfer for the Cell Culture and Fermentation Sciences department. As Senior Scientist, you will be working closely with process development, manufacturing, external CMOs and QA teams to ensure appropriate scale up and transfer of clinical and commercial upstream processes to GMP manufacturing production.
    $87k-124k yearly est.5d ago
  • Bioinformatic Scientist

    Through our partnership with the National Institutes of Health, Kelly Government Solutions offers administrative, IT, engineering, scientific, and healthcare professionals the opportunity to work with the leading medical research center in the world. Kelly Government Solutions is a strategic supplier and business partner to the federal government and its key suppliers. Bioinformatic Scientist with phage display library experience
    $74k-113k yearly est.10d ago
  • Associate Scientist

    Said individual will be working on-site in our Germantown, MD laboratories to develop and validate analytical methods, investigate unexpected/anomalous results, author and critically review quality documentation, data and reports, and perform GMP-compliant stability testing. We are seeking candidates to fill the newly created position of Associate Scientist (Quality Control/Analytical Development) for our headquarters in Germantown, MD. Sirnaomics, Inc. is a leading clinical stage biopharmaceutical company in the discovery and development of RNAi therapeutics for treatment of cancer and fibrotic diseases.
    $66k-94k yearly est.10d ago
  • Viral Diagnostics and Assay Development (VDAD) Scientist

    At CAMRIS, you will notably improve the lives of people at home and abroad. Viral Diagnostics and Assay Development (VDAD) Scientist CAMRIS International, LLC, is a dynamic medical research and development firm that achieves innovative solutions to health and development challenges through high-quality, cost-effective programs and research management services. to support the Pilot Bio-Production Facility (PBF) at the Walter Reed Army Institute of Research (WRAIR) in Silver Spring, Maryland.
    $61k-103k yearly est.8d ago
  • Process Development Scientist

    The process development scientist will support product development strategies to create new and innovative synthetic biology-based cellular medicines. Rise Therapeutics is recruiting a full-time process development scientist with a background in bacterial fermentation to work in our Rockville, Maryland laboratory. Rise Therapeutics is an emerging, privately held company located in Rockville, Maryland which leverages its expertise in synthetic biology and immunological drug development to create novel cellular-based immune therapies.
    $67k-94k yearly est.10d ago
  • Sr. Scientist - Bioprocessing

    The Scientific Team at Russell Tobin & Associates is supporting a world-class biotech/pharmaceutical client near Gaithersburg, MD with a
    $120k yearly5d ago
  • Scientist

    Kaigene was founded in 2022 in North Bethesda. Responsibilities We are seeking a highly motivated and experienced scientist to join our antibody discovery team.
    $69k-101k yearly est.5d ago

Learn More About Principal Scientist Jobs

Average Salary For a Principal Scientist

Based on recent jobs postings on Zippia, the average salary in the U.S. for a Principal Scientist is $119,982 per year or $58 per hour. The highest paying Principal Scientist jobs have a salary over $169,000 per year while the lowest paying Principal Scientist jobs pay $84,000 per year

Updated March 16, 2023
Average Principal Scientist Salary
$102,779 yearly
$58 hourly

5 Common Career Paths For a Principal Scientist


Directors work in show business, whether in a film, a television show, or a theatre production. They are responsible for bringing the material to life. They work with the writers to get a clear vision of how the production should look. They lead the production team in planning for the production, identifying filming or rehearsing schedules, casting for roles, and other aspects that need to be decided upon. Directors provide direction to the actors to ensure that the actors understand their role and will be able to effectively convey emotions to the audience. They also manage all other crew members and communicate their expectations clearly so that everyone on the set is working towards one vision.


Managers are responsible for a specific department, function, or employee group. They oversee their assigned departments and all the employees under the department. Managers are responsible that the department they are handling is functioning well. They set the department goals and the steps they must take to achieve the goals. They are also in charge of assessing the performance of their departments and their employees. Additionally, managers are responsible for interviewing prospective candidates for department vacancies and assessing their fit to the needs of the department. Managers also set the general working environment in the department, and they are expected to ensure that their employees remain motivated.

Research And Development Manager

A research and development manager is responsible for supervising project development procedures to support business operations and identify business opportunities that would pave the way for more revenue resources and profits. Research and development managers monitor the production plans from the conceptualization to the final outputs, inspecting inconsistencies and flaws in every phase and revising strategies as needed to achieve the required specifications and requirements. They delegate tasks to the staff, oversee progress, and conduct research and development programs to maximize productivity and team efforts.

Project Manager

Project managers oversee a specific project related to the organization's business. They manage the whole project from inception to evaluation. They initiate planning with involved departments, follow-through on the plans, ensure smooth execution of the plans, and evaluate the project for further improvements should these be needed. In line with this, project managers also ensure that the project is cost-efficient and well within the budget. They also manage the different work teams involved in the project and ensure that things are running smoothly on this aspect as well.


A principal is responsible for maintaining the orderliness of the school premises and supervising school operations, enforcing strict safety standards, and reiterating regulatory procedures. Principals' duties also include managing and monitoring school budget and expenses, improving security plans, conducting regular meetings and sharing updates with teachers and other school personnel, creating reports for school funding, and setting academic goals for everyone's compliance. A principal must administer excellent leadership, communication, and decision-making skills to handle major administrative tasks in maintaining the school's growth.

Illustrated Career Paths For a Principal Scientist