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In February 2011, the company completed its initial public offering in Israel, pursuant to which the company issued 14,302,300 Ordinary Shares, and 7,151,150 tradable Series 1 Warrants to purchase 7,151,150 Ordinary Shares for aggregate gross proceeds of approximately $14 million.
Following these preclinical studies, in June 2013, the company initiated a Phase IIa proof-of-concept study with RHB-104 for relapsing-remitting multiple sclerosis (“RRMS”) (the “CEASE MS” study) at two clinical sites in Israel.
In March 2014, the company entered into a License Agreement with Temple University to secure direct rights to patents related to the CDT® platform.
TALICIA® was granted Qualified Infectious Disease Product (“QIDP”) designation by the FDA in November 2014.
Salix (now Valeant), which acquired a worldwide exclusive license to RHB-106 and other purgative developments from it, estimated in its 2014 Investor Day that the peak year revenue from their encapsulated bowel prep would reach approximately $280 million.
Xifaxan® is an antibiotic treatment that was approved for the treatment of IBS-D in 2015.
In October 2016 the company reported the results from the MAP diagnostic development program, including an initial validation of its platform PCR (polymerase chain reaction) detection methodology licensed from UCF and developed by Professor Saleh A. Naser.
At the first DSMB meeting, held in December 2016, safety data from the study was reviewed.
According to Ryu YJ et al. (Tuberc Respir Dis, 2016) the incidence and prevalence of NTM lung disease are increasing worldwide, while treatment options remain limited, lengthy and challenging.
The total worldwide sales of multiple myeloma therapies were estimated to exceed $18 billion in 2018 according to GlobalData.
The report also estimated that the sales of therapies for Crohn’s disease in these territories would exceed $12 billion in 2022.
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RedHill Biopharma may also be known as or be related to REDHILL BIOPHARMA LTD, RedHill Biopharma, RedHill Biopharma Ltd, RedHill Biopharma Ltd. and Redhill Biopharma Ltd.