Relay Therapeutics jobs - 3,867 jobs

The Opportunity: Our creative, collaborative, and talented biology group is looking for a strong addition to our team. The ideal candidate will combine a deep understanding of cellular and molecular biology with experience in drug discovery to help drive one of our newest projects from early stages to clinical development. You will contribute to the biology efforts on a dynamic and passionate multi-disciplinary drug discovery team, developing and optimizing cell-based assays to explore mode of action, identifying the appropriate preclinical models to assess target engagement and efficacy. This is a unique opportunity to work cross functionally to build and advance a high impact program toward the clinic. Your Role: Your role will encompass several key responsibilities: You will identify preclinical models that reflect patient pathology and develop assays to use these models in the drug discovery process. You will design, optimize and implement cell-based assays to evaluate the mechanism of action of lead compounds. You will learn and participate in the development of in vivo pharmacology models or GEMM to assess target engagement in vivo . You will utilize your strong analytical and communication skills to interpret and summarize research findings, presenting them effectively at both internal and external meetings. We will rely on you to infuse the latest scientific breakthroughs, ideas, and technologies into your project to drive it forward. This is a unique opportunity to have a significant impact within a fast-paced, collaborative environment, and contribute to the advancement of an interesting drug discovery project on its journey toward clinical development. Your Background: You have a Ph.D with at least 2+ years or a MS with 7+ experience of drug discovery experience. Experience in biotech/pharma is a plus, but not required. You have effectively showcased your leadership abilities through a robust history of contributions to drug discovery programs or peer-reviewed publications. You have a versatile skill set in molecular and cell biology techniques, plate-based assays (e.g. AlphaLISA, HTRF, ELISA, CellTiter-Glo) and high content imaging. You have hands on experience with primary cell culture and genetically engineered cellular systems. Experience in angiogenesis and associated functional assays (e.g. wound healing, 3D cultures) is a plus. You are not afraid to roll-up your sleeves to move your project forward and are comfortable in a rapidly evolving research environment. Your can-do attitude is contagious. You can communicate clearly and enthusiastically your work to internal and external parties. You speak your mind and leverage your expertise to keep your team focused on the most impactful and translational questions. You are passionate about drug discovery and thrive in a highly collaborative environment. Estimated Salary Range: [$103,000 - $147,000]. The range provided above is based on what we believe to be a reasonable estimate for this job at the time of posting. Actual base salary will depend on a number of factors, including but not limited to, a candidate's education, experience, skills and location. #BP1 About Relay Therapeutics Relay Therapeutics is a clinical-stage precision medicines company transforming the drug discovery process with the goal of bringing life-changing therapies to patients. Built on unparalleled insights into protein motion and how this dynamic behavior relates to protein function, we aim to effectively drug protein targets that have previously been intractable, with an initial focus on enhancing small molecule therapeutic discovery in targeted oncology. Our Dynamo platform integrates an array of leading-edge experimental and computational approaches to provide a differentiated understanding of protein structure and motion to drug these targets. We have built a world-class team of leading experts from each of these disciplines, and they are driven by a deep collaboration at every step of our drug discovery process. Our team is equal parts fearless and relentless, with a shared passion for working collaboratively in intellectually stimulating environments. If you're excited by the challenge of putting protein motion at the heart of drug discovery and passionate about making a difference in the lives of patients, join us!

Safety Partners is a Bedford-based Environmental Health & Safety (EHS) consulting company specializing in supporting life science and biotech companies. As a Consulting Safety Officer (CSO), you will have the continual opportunity to create, implement, and maintain Environmental Health & Safety (EHS) programs for our growing list of life science and high-tech clients. Most of your time will be spent with clients at their locations developing and implementing customized programs in hazard communication, chemical safety, emergency preparedness, and facilities safety. You will have a significant opportunity to interact with visionaries, researchers, and senior management at leading firms in fast-paced, highly varied environments. Being comfortable working with all different types of people in different corporate cultures is essential! We take pride in our staff having a strong safety background. Being able to speak peer-to-peer to our clients' EHS departments is critical. Our consultants understand what EHS policies and procedures can mean to an organization and know how to navigate them. If you are self-motivated, adaptable, willing to constantly learn, and want to be an “expert generalist” in EHS for life sciences, come join us! Job Responsibilities Hands-on development and implementation of client EHS programs, including, Chemical Safety, Hazard Communication, Emergency Preparedness, and Additional OSHA-specific safety programs as needed. Establishment and maintenance of EHS permits and licenses in compliance with Federal, State, and Local regulations. Work with EHS teams and facilities teams to develop, manage, and implement worker safety and compliance for facilities and building equipment and systems. Conduct Job Hazard Analyses for hazardous processes, equipment or materials. Conduct Risk Assessments to analyze and evaluate the proper handling of hazardous materials. Establish reporting, complete corrective actions, and ensure corrective actions are completed for non-compliance, un-safe work practices, accidents, and incidents. Work with client staff to bring about a high-level match of EHS culture and worker safety activities to written policies, procedures, instructions, and manuals. Coordinate and facilitate Safety Committees. Prepare and deliver training to fulfill regulatory requirements and ensure client employees are fully aware of the safety program. Coordinate specialized training, such as RCRA, DOT, IATA, OSHA HAZWOPER, Wastewater Operator, CPR, First Aid, and AED. Maintain complete documentation of all aspects of the EHS program. Qualifications Bachelor's degree in related field. Master's degree or PhD preferred. 5+ years of EHS-related work experience. Knowledge of two or more of the following: OSHA, DEP, EPA, RCRA, DOT, DPH, MWRA, NIH, NFPA, DEA, and CDC regulations. Required Skills and Competencies Strong professional communication and written skills. Able to positively interact both internally among the client staff and externally with regulatory agencies. Must be highly organized with strong prioritization skills and possess the ability to manage multiple projects simultaneously. Must have a valid driver's license, the ability to commute to various locations on a daily basis, and potentially multiple locations during the workday. Productivity and resiliency in a dynamic, fast-paced consulting environment. High level of professional judgment. Must be fully vaccinated against COVID-19. Must be able to lift up to 50 lbs. Proficient in the use of Microsoft Office Suite. Experience and comfort with public speaking. What you need to be successful in this role Service-oriented with a personable positive attitude. Ability to successfully negotiate and promote safety programs and services. Strong initiative to dig into resources efficiently and effectively. Ability to independently solve problems with little supervision but recognize when help is needed. Preferred Training: OSHA HAZWOPER Operations Level or above. Industrial Hygiene courses relevant to laboratory settings. OSHA-30 General Industry. As an equal opportunity employer, Safety Partners will provide reasonable accommodation for a disability or sincerely-held religious belief where required by law to do so.

We are a mission-driven organization that was born out of the health care research at Harvard Business School led by Michael Porter and Bob Kaplan. We provide health systems, surgery centers, and physicians with comprehensive insight into their surgical care through our software and empower them to improve their finances and deliver the best care possible to their patients. We integrate sophisticated analytics with deep industry knowledge. We are thought leaders, and our impactful work in improving health care efficiency and effectiveness has been recognized and featured in publications like the Harvard Business Review and The Wall Street Journal . We are well capitalized and backed by leading VCs, including General Catalyst, Founder Collective, Fulcrum Equity Partners, and Tectonic Ventures. Join us in our mission to reshape health care through innovation and insight. Position Overview - Mid-Senior Healthcare Client Partner Role Avant-garde Health seeks a leader in healthcare performance improvement to join our dynamic Customer Success team. You will collaborate closely with hospital executives and clinicians, utilizing our cutting-edge technology and data analytics to identify opportunities for enhancing care processes, reducing costs, and improving outcomes. This is an ideal position for candidates with backgrounds in healthcare technology, advanced data analytics, and technical account management. We are looking for candidates who are passionate about bringing their advanced analytical skills and customer success expertise to drive impactful change within our client hospitals. Your role will be pivotal in fostering long-term relationships with our clients, serving as a trusted partner in their journey towards delivering higher quality, more cost-effective healthcare. Key Responsibilities: Utilize Avant-garde's proprietary SaaS analytics platform to uncover client-specific insights and opportunities for performance improvement. Collaborate with physicians, perioperative directors, supply chain leaders, nursing, and other roles/depts. within hospitals and ASCs to prioritize and develop action plans based on identified opportunities. Perform rigorous data analyses and present compelling insights and recommendations to client stakeholders on a daily, weekly, and quarterly basis. Manage and nurture relationships with multiple stakeholders within client organizations, serving as a trusted advisor. Participate in new client onboarding and training sessions. Monitor client engagement and track key metrics to measure value creation. Drive client growth by extending solutions into new locations or clinical specialties. Contribute to building a learning community among Avant-garde's client base through webinars and discussions. Hybrid location (2 days/week in the Boston office and 3 days/week from home). Travel to client sites for in-person meetings with executives, physicians, etc. (~15% travel). Qualifications: Strong analytical and problem-solving skills, with a focus on data-driven decision-making. Proficiency in data manipulation and analysis using Excel pivot tables. Excellent communication and presentation abilities. Ability to thrive in a fast-paced startup environment. Skills & Experience: Education: Graduate degree required: MBA, MHA, MPH, or equivalent. Experience: 7+ years of experience in healthcare delivery/operations, management consulting, or related fields. Minimum of 3 years focused on healthcare audiences, including hospitals, health systems, physicians, and surgery centers. 3+ years of hospital experience working with management and C-level stakeholders. Experience working with large data sets from multiple sources, running customized reports using Excel Pivot Tables, and presenting the results to physicians and C-level stakeholders strongly preferred.

Associate Spine Specialist (Boston, MA) page is loaded## Associate Spine Specialist (Boston, MA)locations: Massachusettstime type: Full timeposted on: Posted 25 Days Agojob requisition id: JR104911At Globus Medical, we move with a sense of urgency to deliver innovations that improve the quality of life of patients with musculoskeletal disorders. Our team is inspired by the needs of these patients, and the surgeons and healthcare providers who treat them. We embrace a culture of exceptional response by partnering with researchers and educators to transform clinical insights into tangible solutions. Our solutions improve the techniques and outcomes of surgery so patients can resume their lives as quickly as possible The Associate Spine Specialist will work together with the Spine Territory Manager and will have territory coverage, inventory management, and limited sales responsibilities. The Associate Spine Specialist will represent the company in accordance with the company's quality policy and procedures.**Essential Functions****:*** Gains and consistently increases product knowledge through formal sales training; surgeon speaker programs, attends surgeries/operating room visits, and industry research* Meeting or exceeds all sales goals and objectives assigned* Conducts sales calls to promote, sells, and services Globus Medical products and services to existing and competitive customers based on a strategic plan* Assists the Spine Territory Manager on field calls for assigned geography and address and problems that arise on the account* Performs field ride along with the Area Director and Spine Territory Manager on a regular basis* Develops and increases customer base and continually enhances Globus product market share within assigned territory* Provides feedback regularly on topics such as product development opportunities, new target accounts, sales performance, and market feedback* Maintains conduct that is aligned with company quality policy and procedures, and protects confidentiality with proprietary information* Stays current with all compliance training requirements* Adheres to the letter and spirit of the company Code of Conduct, the AdvaMed Code, MedTech Code, and all other company policies.* Ensures Compliance with applicable governmental laws, rules, and regulations, both in the United States and internationally, by completing introductory and annual training and maintaining knowledge of compliance as it applies to your role* Represents the company in a professional manner and uphold the highest standards of ethical business practices and socially responsible conduct in all interactions with other employees, customers, suppliers, and other third parties*Reasonable accommodations may be made to enable individuals with disabilities to perform these* essential *functions.***Qualifications****:*** 1-2 years' successful spine sales experience preferred, may consider other healthcare related sales and or business to business sales experience* Bachelor's degree in Science or Business* Exemplary ability to listen, communicate and influence* Ability to travel as necessary, which may include nights and/or weekends* Strong understanding of spinal anatomy* Ability to make sales presentations with positive results**Physical Demands****:**The physical demands listed here are representative of those that must be met by and employee to successfully perform the essential functions of this job.* Required to sit; climb or balance; and stoop, kneel, crouch or crawl* Required to regularly lift and/or move up to 10 pounds, and occasionally lift and/or move up to 25 pounds* Required to possess specific visons abilities, including: close vision, distance vision, color vision, peripheral vision, depth perception and capacity to adjust focus.**Our Values:**Our Life Moves Us philosophy is built on four values: Passionate About Innovation, Customer Focused, Teamwork, and Driven.* **Passionate about Innovation**: Improving patient care by delivering advanced technology to our customers is at the core of what we do. We are passionate in our role in improving the lives of patients by continuously developing better solutions.* **Customer Focused**: We listen to our customers' needs and respond with a sense of urgency.* **Teamwork**: Working together, anything is possible. We value every person on our team and treat each other with respect. We are accountable to one another and support each other. Together, we make each other stronger.* **Driven**: We pursue our mission with energy and passion. We are nimble, results-oriented and decisive. We overcome obstacles that arise in our quest to deliver solutions that will improve the lives of our customers and patients. **Equal Employment Opportunity:**Globus Medical is an equal opportunity employer. All applicants will receive consideration for employment without regard to race, color, religion, gender, sexual orientation, age, disability, marital status, pregnancy, national origin or citizenship. We are committed to a diverse workforce. We value all employees' talents and support an environment that is inclusive and respectful. **Other Duties:**Please note this job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities and activities may change at any time with or without notice. #J-18808-Ljbffr

Harbor House Collective is a minority-owned, family-run, vertically integrated marijuana establishment in Massachusetts, involved in the cultivation, manufacturing, and dispensing of premium adult-use cannabis. As one of the state's premier cannabis companies, HHC is known for its award-winning flower and unwavering commitment to quality, innovation, and authenticity. We are dedicated to producing and delivering the highest quality cannabis in the market. Role Description We are seeking a highly skilled Maintenance Technician with strong HVAC expertise to support the day-to-day facility needs of our cultivation, processing, and retail environments. The ideal candidate is a hands-on problem solver with deep knowledge of HVAC systems, as well as experience in electrical, plumbing, and mechanical maintenance. This role is critical to ensuring our environmental systems remain stable, efficient, and compliant-keeping our cannabis production running at the highest level. Key Responsibilities: HVAC & Environmental Systems Perform installation, preventive maintenance, troubleshooting, and repair of HVAC systems, including RTUs, chillers, dehumidifiers, mini-splits, and air-handling units. Ensure precise calibration of climate control systems to maintain strict cultivation parameters. Monitor, adjust, and optimize environmental controls (temperature, humidity, airflow, CO₂) across multiple grow rooms. Maintain and troubleshoot building management systems (BMS) and cultivation automation platforms. General Maintenance Inspect, maintain, and repair plumbing, electrical, and mechanical systems. Support cultivation and post-harvest equipment (lights, irrigation, fertigation units, pumps, fans, trimmers, packaging machines). Track service records, manage equipment lifecycles, and reduce downtime through proactive repairs. Compliance & Safety Follow all state and local regulations related to cannabis facility operations. Maintain safety standards, keeping all work areas clean, organized, and hazard-free. Document maintenance activities and inspections in compliance with company SOPs and regulatory requirements. Collaboration Respond promptly to maintenance requests from cultivation, processing, and retail teams. Work with third-party vendors and contractors for specialized HVAC or equipment repairs. Communicate issues, updates, and project statuses to management regularly. Skills & Qualifications 3+ years of commercial or industrial facility maintenance experience, with proven HVAC expertise. Ability to diagnose, repair, and optimize HVAC systems in high-demand, high-humidity environments. Working knowledge of electrical, plumbing, and mechanical systems. Ability to read and interpret blueprints, schematics, and technical manuals. Hands-on, adaptable, and able to work independently under pressure. Must be 21+, pass a background check, and be eligible to work in a licensed cannabis facility. This role offers a starting salary of $80,000-$100,000 Preferred Skills: Direct experience with cannabis cultivation or controlled-environment agriculture. Familiarity with cultivation environmental systems and controls (e.g., Aroya, Innotech). Experience with automation and building management systems (BMS). Basic carpentry, drywall, or general construction skills.

A leading healthcare company in Boston is seeking a Senior Manager of AI Engineering to lead the strategy for next-generation AI systems. This role involves defining the architecture, mentoring teams, and ensuring system integrity. The ideal candidate has extensive leadership experience in AI development and a strong background in agile methodologies. The position offers a competitive salary range of $173,430 - $211,970, along with comprehensive benefits. #J-18808-Ljbffr

NYC/Boston Added 12/22/2025 Beam Therapeutics is a biotechnology company committed to establishing the leading, fully integrated platform for precision genetic medicines. To achieve this vision, Beam has assembled a platform with integrated gene editing, delivery and internal manufacturing capabilities. Beam's suite of gene editing technologies is anchored by base editing, a proprietary technology that is designed to enable precise, predictable and efficient single base changes, at targeted genomic sequences, without making double‑stranded breaks in the DNA. This has the potential to enable a wide range of therapeutic editing strategies that Beam is using to advance a diversified portfolio of base editing programs. Beam is a values‑driven organization committed to its people, cutting‑edge science, and a vision of providing life‑long cures to patients suffering from serious diseases. Position Overview: We are building a best‑in‑class Field Medical organization as a natural next step in the growth of our Medical Affairs organization at Beam therapeutics! This Director (or Associate Director) level MSL will own a defined US territory with primary responsibility in sickle cell disease (SCD) and shared accountability across the Beam pipeline, including Alpha‑1 antitrypsin deficiency (Alpha‑1) and glycogen storage disease 1a (GSD). You will architect territory strategy, onboard priority treatment centers, engage KOLs and HCPs, generate actionable insights, and drive pre‑commercial launch readiness in close collaboration with cross‑functional partners. Responsibilities: Develop and execute territory strategy: map treatment centers, referral networks, transplant/infusion sites, cell‑collection capabilities, payers, and advocacy groups; prioritize accounts and set measurable objectives. Support treatment center onboarding: coordinate scientific and operational readiness aligned with SOPs, compliance, and patient journey requirements; partner with internal teams for qualification and activation. Build trusted relationships with KOLs and HCPs: deliver fair‑balanced, evidence‑based education on rare diseases, cell and gene therapy science, and Beam's platform; foster advocacy and awareness. Educate stakeholders on disease state, therapeutic landscape, and company platform to drive awareness and credibility in the rare disease and CGT space. Generate high‑quality insights from field interactions: synthesize trends and communicate actionable recommendations to Medical Affairs leadership and cross‑functional partners. Collaborate on pre‑launch planning: align with Medical Strategy, Publications, Medical Information, Value & Evidence, and Medical Operations to ensure scientific messaging, data dissemination, and field tools are ready for first commercial launch. Support clinical activities: identify potential sites, assist with feasibility assessments, and promote best practices for enrollment and retention while maintaining medical/scientific independence. Partner cross‑functionally with Commercial, Market Access, and Clinical teams while preserving medical independence; coordinate account plans to ensure seamless patient access and avoid duplication. Represent the company at congresses and external scientific meetings: plan and execute presence, engage in meaningful scientific exchanges, and follow up to strengthen visibility and credibility. Provide education and resources to treatment centers on operational readiness for advanced therapies, including apheresis and cell‑handling processes. Serve as a trusted resource for compliance and ethical standards: ensure all interactions and materials meet company policies, regulatory requirements, and industry codes. Maintain operational excellence: document activities and insights in CRM, monitor KPIs, and continuously improve processes, content, and tools. Prepare and deliver training for internal teams and external stakeholders on rare disease management and CGT fundamentals to support launch readiness. Act as a scientific ambassador for the company: articulate the value of the platform and pipeline to diverse audiences including clinicians, researchers, and advocacy groups. Monitor evolving evidence and competitive landscape in rare disease and CGT; share updates internally to inform strategy and decision‑making. Qualifications: Advanced scientific degree (PharmD, PhD, MD, or equivalent). ~10+ years industry experience in Medical Affairs with significant Field Medical tenure. Rare disease expertise required; hematology strongly preferred with emphasis on SCD. Small biotech experience preferred; demonstrated impact in resource‑constrained settings. Launch experience (pre‑approval to post‑launch), ideally in CGT or complex specialty (buy‑and‑bill) environments. Proven territory management and account planning capability across complex ecosystems (academic centers, community networks, payers, advocacy). Independent, proactive operator with strong ownership; cross‑functional collaboration with Clinical, Regulatory, Commercial, Medical Operations, and Publications while maintaining medical/scientific integrity. Outstanding communication skills; ability to translate complex science into clear, credible narratives. Analytical strength for insight collection, synthesis, and actionable recommendations. Travel up to ~60% across assigned territory. Beam Pay Range $180,000 - $220,000 USD As set forth in Beam Therapeutics's Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law. #J-18808-Ljbffr

A leading life sciences company is seeking a Technical Sales Specialist to drive sales and support customers in the northeastern US. The ideal candidate will have a strong background in biology, 5+ years of technical sales experience, and expertise in immunohistochemistry. Responsibilities include achieving sales goals, conducting demos, and collaborating with teams to enhance customer experience. This fully remote position offers competitive insurance benefits and career development opportunities. #J-18808-Ljbffr

A leading technical solutions provider is seeking an engineer specialized in the medical device industry. The role involves designing manufacturing processes and ensuring compliance with safety regulations. Candidates should have a BBA in Engineering, knowledge in CSV, and problem-solving skills (Yellow or Green Belt). The position offers an opportunity to work with innovative technologies in a dynamic environment located in Caguas, Puerto Rico. #J-18808-Ljbffr

A pioneering biotech company in Boston is seeking a Head of Finance to build and lead its finance and accounting function. This role involves establishing core financial processes, ensuring accurate revenue recognition, and supporting budgeting and forecasting. Ideal candidates will possess a Bachelor's or Master's degree in Accounting or Finance, with over 10 years of relevant experience and strong technical expertise in accounting. Join this dynamic team to push the frontiers of synthetic biology and play a key role in a rapidly growing startup. #J-18808-Ljbffr

A healthcare organization is seeking a board-certified or board-eligible neurosurgeon to join its team in Massachusetts. The role emphasizes elective spinal surgery and managing CNS tumors. This position offers competitive compensation, comprehensive benefits, and opportunities for professional development. Candidates should possess proficiency in spinal surgical techniques and a commitment to patient-centered care. Living in Cape Cod provides a unique lifestyle with coastal charm and easy access to urban amenities. #J-18808-Ljbffr

Massachusetts Eye and Ear is a world-renowned specialty hospital focused on treating disorders of the eye, ear, nose, throat, and head and neck regions. Affiliated with Harvard Medical School, the institution is a leader in patient care, education, and research in its areas of expertise. Beyond offering advanced medical and surgical services, Mass Eye and Ear conducts cutting-edge laboratory and clinical research to improve care for current and future patients. Serving locally and globally, the hospital is committed to improving lives through innovative treatments and academic excellence in healthcare. We are seeking postdoctoral fellows in multiple groundbreaking projects focused on hearing restoration, encompassing gene therapy for genetic hearing loss and inner ear hair cell regeneration, from animal models to humans. Our work includes: Gene and Editing Therapy for Genetic Hearing Loss: We are working on gene and editing therapy for genetic hearing loss and advancing our findings toward clinical applications. Our gene and editing therapies have successfully restored hearing in multiple mouse models (Gao et al., Nature, 2017; Du et al., Mol Ther, 2023; Yong et al., Nat Commun, 2023; Zhu et al., Sci Transl Med, 2024; Wei et al., JCI, 2025). The projects include the development of new technologies (e.g. RNA editing, epigenetic modifications, sh RNA) for different forms of genetic hearing loss. We are conducting multiple IND-enabling studies for gene and editing therapies with the goals to initiate clinical trials in 3 years. The work is supported by the NIH SCGE program (*********************************************************************** Regeneration of Inner Ear Cells: We focus on the regeneration of diverse inner ear cell types, including hair cells, neurons, and supporting cells, in adult mouse models. Our approach leverages Myc/Notch co-activation for reprogramming (Shu et al., Nat Commun, 2019), complemented by a drug-like cocktail we have developed that successfully induces hair cell regeneration in the adult cochlea in vivo (Quan et al., PNAS, 2023). We have identified critical molecules that promote ganglion neurite outgrowth, which demonstrated therapeutic effects on speech recognition deficiencies mediated by synaptopathy. The projects aim to bring the new approaches to repair, rejuvenate and regenerate hair cells, neurons and synapses to restore hearing from animal models to humans. Our laboratory employs state-of-the-art technologies, including in vitro adult cochlea explant culture, reprogramming, sc RNAseq, inner ear organoids, genome editing, gene therapy, viral and non-viral delivery, and physiological function analysis. We are collaborating with the industry, working with CROs and interacting with the FDA to bring our work towards the clinic. We are pioneers in clinical translational applications, having conducted the first successful OTOF gene therapy trial in children born with complete hearing loss, resulting in restored hearing and speech capabilities (Lv et al., The Lancet, 2024; Wang et al., Nat Med, 2024). Our lab is part of Eaton-Peabody Laboratories, the largest hearing research center globally, renowned for its diverse research programs in hearing science. We offer a unique and exciting opportunity for candidates interested in advancing basic research to translational applications, including human studies. Candidate Requirements: We seek individuals with a Ph.D., M.D./Ph.D., or M.D. For gene/editing therapy, we seek candidates with a strong background in genetic hearing loss, in vivo animal inner ear study, AAV-mediated gene therapy and editing technology. For inner ear regeneration, we seek candidates with strong background in molecular biology, cellular biology, genetics, promoter analysis, gene editing, RNAseq, and animal models. A strong track record of scientific publications is essential. Please email a curriculum vita, a description of research accomplishments and names of three references to: Zheng-Yi Chen ************** Associate Professor Massachusetts Eye & Ear/Harvard Medical School Boston, MA 02114 Zheng-Yi_*********************

The Senior Consulting Manager supports large-scale transformations at Dana-Farber as well as planning and decision-making regarding the company's most critical business issues and strategic priorities. The Senior Consulting Manager employs a hypothesis-driven approach to planning, facilitates Institute leadership decisions on complex topics, provides in-depth analysis, and maintains project structure to drive large-scale organizational change. They will work on multiple highly complex, ambiguous projects simultaneously. May work independently or in partnership with Principal, Director and Senior Directors and may lead small project teams. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. Responsibilities Overall Drives large-scale organizational change Works on multiple Institute-wide, highly complex, ambiguous projects simultaneously Participates in the identification of value creation opportunities and implements planning structures to realize value Hypothesis-Driven Approach to Planning Applies a structured, hypothesis-driven approach to problem solving and using analytical tools and frameworks to develop solutions to complex business challenges Conducts analysis, research and projections for complex negotiations and strategic decisions; develops and implements systems to organize and analyze data Creates business cases for strategic programs and initiatives Leads ad hoc research and due diligence relating to new projects and initiatives; translates business and competitive intelligence research back into projects Articulates recommendations or options to support a definitive decision Transformation & Execution Creates project roadmaps and workplans that align with project vision and goals Tracks, reports on, and executes project workplans Identifies and escalates issues and risks Manages project management office functions including program management, tools and methodologies, roadmap development and management, risk mitigation, reporting, interdependency management, resource management, strategic communications, impact creation plan management, financial management, change management, and governance and stakeholder management Works with cross-functional teams to understand the impact of changes on different departments and ensure that transformation goals are aligned across the organization Collaboratively plans with anticipated new clinical partners Identifies and highlights likely business and financial impacts associated with program planning or expansion, as well as required implementation dependencies, issues, and risks to serve as input to prioritization and planning process Conducts impact analyses to assess Institutional/stakeholder readiness for change adoption and applies change management processes and tools to support adoption of change. Supports the design, development, delivery, and management of project/change related communications Stakeholder Management Works collaboratively with cross-functional teams and interacts independently with staff, mid-level, and executive leaders throughout the organization (including C-Suite) Builds and maintains consensus with stakeholders on project goals, critical issues, workplan, implications, recommendations, and implementation plan Develop and secure stakeholder commitment to recommendations and implement plans Maintains relationships with stakeholders and keeps them up to date on project status Consulting Infrastructure Collaboratively creates consulting frameworks and approaches that can be leveraged across projects and fit to purpose to accelerate speed to insights and results Collaboratively develops and defines project infrastructure (work plans, roadmaps, timelines, resources, milestones, KPIs, etc.); anticipates, identifies, manages and resolves risks to project status, milestones, timelines; develops and presents updates/metric reports to leadership Creates work products based on consulting best practices Utilizes and continues to improve and refine a standard set of strategy development, consulting, and business planning tools People Leadership Work collaboratively with department and organizational peers to ensure maximum performance by providing purpose, direction and motivation May lead small project teams Contributes to Planning and Consulting staff development, as well as internal departmental process and performance improvement Models and encourages high level of attention to detail and a commitment to producing high-quality results SUPERVISORY RESPONSIBILITIES: May provide training and guidance to others, including project team members. Qualifications Bachelor's degree required; relevant Master's degree strongly preferred (MBA, MPH, MHA, MSW). 5 years of professional work experience, including at least 3 years in strategic planning, business planning, and/or consulting, required. KNOWLEDGE, SKILLS, AND ABILITIES REQUIRED: Demonstrated ability to work closely and effectively with all levels of the organization Knowledge of large-scale transformations, strategic planning, and consulting practices, as well as experience within the healthcare field Excellent planning, project management, facilitation, and organizational skills, with the demonstrated ability to work on multiple concurrent projects simultaneously in a complex, deadline-driven environment Excellent written and oral communication skills with ability to deliver presentations to a wide variety of audiences -up to and including executive level and C-Suite executives Excellent problem-solving skills Role-model results-orientation, teamwork, communication, and interpersonal skills to other members of team Demonstrated ability to navigate complex and consensus driven environments to facilitate decision making Ability to effectively design and facilitate large meetings Ability to deal effectively with highly ambiguous and evolving situations while exhibiting calm presence to stakeholders and team members Pay Transparency Statement The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications. For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA) $143,800 - $165,000 At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply. Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law. EEOC Poster #J-18808-Ljbffr

The Opportunity: As Associate Director/Director, Statistical Programming, you will be accountable for delivery, integrity and quality of Relay's statistical programming across the clinical studies. You will be an integrated member of the Relay Tx scientific team, responsible for the in-house statistical programming expertise for the execution of clinical studies that will translate Relay's innovative science into impactful medicines for patients. Your role: You will function as lead programmer to provide technical and business expertise in support of statistical programming deliverables. You will oversee the day-to-day statistical programming activities, timelines and deliverables for in house statistical programming as well as outsourced services. You will ensure compliance with global regulatory requirements and quality standards. You will lead/review SDTM and ADaM specifications, Defines, Reviewer's Guide for regulatory submissions, CDISC compliance. You will generate/validate CDISC SDTM, ADaM compliant datasets and TLFs based on SAP. You will create, manage and maintain the programming specifications for the integration of data across studies in support of ISS/ISE. You will produce and/or validate tables, listings, figures and analysis datasets in response to regulatory requests, publication requests, and ad-hoc analyses; write specifications to describe programming needs. You will identify problems and develops global tools that increase the efficiency and capacity of the Statistical Programming group. Your background: You should ideally have a master's degree in statistics, mathematics, computer science, or related scientific/medical field. You have 6-10+ years of experience (considering both Associate Director and Director level) of (SAS) statistical programming experience in the pharmaceutical/biotechnology industry as a statistical programmer. Oncology experience is preferred. You have advanced SAS programming skills - procedures and options commonly used in clinical trial reporting, including Macro language, BASE SAS, SAS/STAT, and SAS/GRAPH, validation/QC, experience generating listings, tables, figures desirable. You have a strong and hands-on knowledge of CDISC SDTM/ADaM models and transforming raw data into these standards. You are a motivated self-starter who is capable of flourishing in a fast-paced small company environment. You are a creative problem-solver with excellent communication. You have strong interpersonal and organizational skills, with a high degree of attention to detail. Estimated Salary Range: [$154,000 - $219,000]. The range provided above is based on what we believe to be a reasonable estimate for this job at the time of posting. Actual base salary will depend on a number of factors, including but not limited to, a candidate's education, experience, skills and location. #BP1 About Relay Therapeutics Relay Therapeutics is a clinical-stage precision medicines company transforming the drug discovery process with the goal of bringing life-changing therapies to patients. Built on unparalleled insights into protein motion and how this dynamic behavior relates to protein function, we aim to effectively drug protein targets that have previously been intractable, with an initial focus on enhancing small molecule therapeutic discovery in targeted oncology. Our Dynamo platform integrates an array of leading-edge experimental and computational approaches to provide a differentiated understanding of protein structure and motion to drug these targets. We have built a world-class team of leading experts from each of these disciplines, and they are driven by a deep collaboration at every step of our drug discovery process. Our team is equal parts fearless and relentless, with a shared passion for working collaboratively in intellectually stimulating environments. If you're excited by the challenge of putting protein motion at the heart of drug discovery and passionate about making a difference in the lives of patients, join us!

Job Description & Requirements OB/GYN Physician Boston Area StartDate: ASAP Pay Rate: $322020.00 - $463535.00 A well-established hospital in south Boston is rapidly growing and adding OB/GYNS to be a central hub for all OB/GYN services in the market. This position offers an incredible quality of life, high financial incentive, and the ability to live in a desirable location in Boston and the surrounding suburbs.

A leading healthcare institution in Boston seeks a Sr. Principal Scientist to oversee operations in a GMP lab, focusing on the production and quality control of radiopharmaceuticals. The ideal candidate will have extensive experience in aseptic operations, knowledge of QC methodologies, and a strong educational background in pharmaceuticals. This role requires meticulous documentation, adherence to GMP standards, and the ability to thrive in a fast-paced environment, contributing to pioneering advancements in patient care. #J-18808-Ljbffr

The Opportunity: As the TMF Specialist, you will be responsible for working across clinical study teams in line with TMF processes across the development portfolio, with regards to the filing and maintenance activities for clinical studies during the study start-up, maintenance and close-out periods. To be successful, you will be detail-oriented, with a flexible and solution-oriented outlook and the ability to support team members within Relay Therapeutics and with our CRO partners under the guidance of the Sr. Manager, eTMF. Your Role: You will engage in assessing eTMF metrics for completeness, timeliness, and quality. You will facilitate TMF QC Reviews and ensure issues identified are tracked to resolution. You will help build and maintain strong partnership with key stakeholders to ensure cross-functional eTMF engagement. You will engage with CROs/Vendors to ensure responsibilities around eTMF are clearly defined and executed. You will contribute to eTMF study creation, maintenance, and archival, ensuring all activities are performed in accordance with Relay's Standard Operating Procedures (SOPs), ICH-GCP Guidelines, EMA, FDA, and other health authority requirements. Applies risk-based quality management (RBQM) principles to Trial Master File (TMF) oversight, ensuring proportionate review, inspection readiness, and regulatory compliance. You will help identify business needs to assess the current state of eTMF and identify opportunities for process improvement, ensuring industry best practice is implemented. You will participate in the creation and review of Study-specific eTMF Plans, Study-specific TMF Indexes, and QC approach across all studies. You will participate in discussions with IT and eTMF system managed services relations and topics. You may participate in health authority inspections and audits. Your Background: You have 2-5 years industry experience with TMF/eTMF. You have hands-on experience with TMF QC processes, including both individual document quality checks and TMF completeness reviews. You have working knowledge of ICH-GCP, FDA, and EMA regulations. You have working knowledge of the CDISC TMF Reference Model. Veeva Vault eTMF experience a plus. You are a motivated self-starter who has demonstrated critical thinking skills. You have excellent organizational skills with the ability to multi-task and prioritize effectively in an extremely fast-paced and dynamic environment. You have outstanding verbal and written communication skills, allowing for an open and effective dialogue throughout the organization. You have a strong work ethic, excellent problem-solving ability, and attention to detail and quality are critical to success. Estimated Salary Range: [$68,000 - $97,000]. The range provided above is based on what we believe to be a reasonable estimate for this job at the time of posting. Actual base salary will depend on a number of factors, including but not limited to, a candidate's education, experience, skills and location. #BP1 About Relay Therapeutics Relay Therapeutics is a clinical-stage precision medicines company transforming the drug discovery process with the goal of bringing life-changing therapies to patients. Built on unparalleled insights into protein motion and how this dynamic behavior relates to protein function, we aim to effectively drug protein targets that have previously been intractable, with an initial focus on enhancing small molecule therapeutic discovery in targeted oncology. Our Dynamo platform integrates an array of leading-edge experimental and computational approaches to provide a differentiated understanding of protein structure and motion to drug these targets. We have built a world-class team of leading experts from each of these disciplines, and they are driven by a deep collaboration at every step of our drug discovery process. Our team is equal parts fearless and relentless, with a shared passion for working collaboratively in intellectually stimulating environments. If you're excited by the challenge of putting protein motion at the heart of drug discovery and passionate about making a difference in the lives of patients, join us!

A leading healthcare organization in Massachusetts seeks an experienced Senior Consulting Manager to support large-scale transformations. Responsibilities include driving change, managing complex projects, and stakeholder engagement. The ideal candidate will have a strong background in strategic planning and consulting, with a focus on effective communication and problem-solving skills. Offers competitive salary and an inclusive environment. #J-18808-Ljbffr

Performs a variety of routine and highly specialized diagnostic tests and specialized procedures. Assures quality of the results and communicates relevance of results to other health care professionals. Key Responsibilities: Performing a variety of moderate and highly complex and diagnostic laboratory testing under general supervision in the laboratory. May perform specialized procedures in special laboratory sections unique to each laboratory's discipline. Evaluating whether the results are abnormal/critical and takes appropriate action internally/externally according to laboratory guidelines. Recording results of tests with all supporting documentation for clinical interpretation. Performing regularly scheduled quality control, preventative maintenance, and calibration of equipment according to laboratory guidelines. Performs all troubleshooting and repair. Participating in department continuing education including training program expanding scope of knowledge. Providing general assistance to less experienced laboratory personnel. Communicating principle/theory to physicians and other professional staff. Ensuring accurate test results by following good lab practices. Can identify problems as if unsure of resolution seeks appropriate assistance. Performing a variety of special projects and additional work as needed/assigned. Observing guides, verifying and checks documentation of less experienced lab personnel. Training and teaching laboratory personnel and others. Contributes to the continuing education program May act as lead in absence of supervisor/manager. May prepare schedule or draft procedures. Performing a variety of moderate to highly complex and specialized diagnostic laboratory testing. Performing special projects as assigned. May perform testing unique to the specific discipline in the laboratory and at the bedside. Minimum Qualifications Education: Associate's Degree AND successful completion of an ASCP/NAACLS accredited Medical Technology/Medical Laboratory Science program required Bachelor's Degree AND successful completion of an ASCP/NAACLS accredited Medical Technology/Medical Laboratory Science program preferred. Experience: Minimum 3 years of Clinical Lab Science experience required 5 years Clinical lab experience preferred Certification: National certification preferred Certification required for related science degreed individuals Shift/hours: Monday - Friday, 11am - 7:30pm including on call hours as needed Location: Needham Sign on Bonus: $7,500 one time sign on bonus Boston Children's Hospital offers competitive compensation and unmatched benefits including flexible schedules, affordable health, vision and dental insurance, child care and student loan subsidies, generous levels of time off, 403(b) Retirement Savings plan, Pension, Tuition and certain License and Certification Reimbursement, cell phone plan discounts and discounted rates on T-passes. Experience the benefits of passion and teamwork. LI-Onsite The posted pay range is Boston Children's reasonable and good-faith expectation for this pay at the time of posting. Any base pay offer provided depends on skills, experience, education, certifications, and a variety of other job-related factors. Base pay is one part of a comprehensive benefits package that includes flexible schedules, affordable health, vision and dental insurance, child care and student loan subsidies, generous levels of time off, 403(b) Retirement Savings plan, Pension, Tuition and certain License and Certification Reimbursement, cell phone plan discounts and discounted rates on T-passes. Experience the benefits of passion and teamwork.