Relay Therapeutics jobs in Cambridge, MA - 3582 jobs

The Opportunity: As Clinical Project Manager, you will be accountable for managing clinical studies that will lead the biopharma industry in speed and quality of clinical study design and execution. You will be an integrated member of the Relay Tx scientific team, responsible for the execution of clinical studies that will translate Relay's innovative science into impactful medicines for patients. The Role: You will oversee the day-to-day operations of study execution, with a focus on site oversight from study startup to study closeout, patient enrollment, monitoring, compliance, and data flow and metrics from the clinical sites, CROs and vendors. You will collaborate with a dynamic Relay cross-functional team to deliver clinical studies that are on time and within budget guidelines, while ensuring quality in accordance with the protocol and ICH GCP guidelines. You will develop and maintain strong relationships with investigators, clinical site staff, and vendors globally, with the capability of understanding and explaining complex scientific topics to these stakeholders. You will manage reports for communicating study progress and key metrics to Senior Management and program teams. You will contribute to or author key study documents including, but not limited to, protocols, informed consent forms, case report forms, study governance committee charters (e.g., data monitoring committee), study plans and clinical study reports. You will be accountable for effective vendor management by: serving as primary point of contact for contracted CROs and vendors identifying potential risks and proactively resolving issues with CROs and vendors ensuring vendor contracts meet requirements and are efficiently executed with key performance indicators partnering with the vendor to ensure accurate budgeting and accrual of costs throughout duration of each clinical study You will ensure reliable quality data are delivered by reviewing monitoring reports, protocol deviations, clinical data listings and performing or overseeing site monitoring visits, as needed. You will develop action plans to address protocol compliance, safety, data and administrative issues with clinical sites and CROs. You will coordinate with CROs on site selection, IRB/EC submissions, site initiation and close-out planning. You will provide oversight and ensure maintenance of clinical trial master files (TMF) to ensure compliance with required regulatory and ICH GCP quality standards and consistency with SOPs. You will partner with the CRO to lead, plan, and execute clinical Investigator meetings study meetings, as needed. You and your team will participate in preparation of regulatory filings (e.g. IND, NDA, orphan drug applications etc.) as needed. You will ensure inspection readiness by collaborating with CROs and providing support to clinical sites to prepare for and respond to audit/inspection findings conducted by internal QA and external regulatory agencies. You will assist with the onboarding and mentoring of new or junior clinical operations associates. Your Background: You should ideally have 5+ years of experience in clinical study management. Sponsor experience is strongly preferred. You are recognized as a clinical operations expert, with a prior track record of success to facilitate study execution, accelerate timelines, maintain data integrity, and satisfy health authority requirements. You have experience in executing clinical studies across various phases is desirable. Expertise in oncology drug development is preferred. You have a strong and current knowledge in global regulatory and compliance requirements including but not limited to US CFR, EU CTD, and ICH GCP applicable to the conduct of clinical trials You have experience in CRO, vendor and laboratory oversight. You are a motivated self-starter who is capable of flourishing in a fast-paced small company environment. You are a creative problem-solver with excellent communication and public speaking skills. You have strong interpersonal and organizational skills, with a high degree of attention to detail. You are pragmatic and able to manage multiple projects and needs effectively. Estimated Salary Range: [$102,000 - $145,000]. The range provided above is based on what we believe to be a reasonable estimate for this job at the time of posting. Actual base salary will depend on a number of factors, including but not limited to, a candidate's education, experience, skills and location. #JO1 About Relay Therapeutics Relay Therapeutics is a clinical-stage precision medicines company transforming the drug discovery process with the goal of bringing life-changing therapies to patients. Built on unparalleled insights into protein motion and how this dynamic behavior relates to protein function, we aim to effectively drug protein targets that have previously been intractable, with an initial focus on enhancing small molecule therapeutic discovery in targeted oncology. Our Dynamo platform integrates an array of leading-edge experimental and computational approaches to provide a differentiated understanding of protein structure and motion to drug these targets. We have built a world-class team of leading experts from each of these disciplines, and they are driven by a deep collaboration at every step of our drug discovery process. Our team is equal parts fearless and relentless, with a shared passion for working collaboratively in intellectually stimulating environments. If you're excited by the challenge of putting protein motion at the heart of drug discovery and passionate about making a difference in the lives of patients, join us!

Family Medicine physician employment in Massachusetts : Join a hospital-employed family medicine practice located just outside Boston, offering an exceptional work/life balance in a community that truly values patient-centered care. This position provides a supportive, team-based environment with strong clinical and administrative resources to help you thrive. Enjoy the convenience of easy access to downtown Boston while working in a welcoming suburban setting. 4 day clinical week with 8 administrative hours. Epic EMR. Join 6 MD's and 1 APP. 1:1 MD to Medical Assistant. Mix of young to elderly patients. !function () {var reb2b = window.reb2b = window.reb2b || []; if (reb2b.invoked) return;reb2b.invoked = true;reb2b.methods = ["identify", "collect"]; reb2b.factory = function (method) {return function () {var args = Array.prototype.slice.call(arguments); args.unshift(method);reb2b.push(args);return reb2b;};}; for (var i = 0; i < reb2b.methods.length; i++) {var key = reb2b.methods[i];reb2b[key] = reb2b.factory(key);} reb2b.load = function (key) {var script = document.create Element("script");script.type = "text/javascript";script.async = true; script.src = "************************************************* + key + "/EN4M0H10ZWOM.js.gz"; var first = document.get ElementsByTagName("script")[0]; first.parent Node.insert Before(script, first);}; reb2b.SNIPPET_VERSION = "1.0.1";reb2b.load("EN4M0H10ZWOM");}(); Board Certified or Board Eligible Medical Doctor with or w/o US residency with current US work visa.

Junior Bioinformatics Student Researcher (Single-Cell Biology) We are seeking a motivated student with emerging interest in computational biology to join our research group and contribute to single-cell transcriptomics projects. This position is ideal for a student eager to build experience in modern genomics, coding for biological analysis, and collaborative research in a wet-lab + computational environment. Role Overview The Junior Bioinformatics Researcher will assist with processing and analyzing single-cell and spatial transcriptomics data, support ongoing projects, and learn standard analysis workflows under mentorship from lab members. Key Responsibilities · Assist with data parsing, preprocessing and QC of single-cell RNA-seq and spatial transcriptomics datasets · Apply analysis tools such as Seurat, Scanpy, and basic Linux command-line workflows · Support integration, clustering, differential expression, and cell-type annotation · Help maintain organized scripts, notebooks, and data files · Generate visualizations and figures for meetings and data reviews · Participate in lab discussions, contribute ideas, and develop independent skills over time Training & Skills Development The student will gain experience in: · R/Python coding for biological data analysis · Single-cell pipelines (10x Genomics, Cell Ranger, Seurat/Scanpy) · Data visualization and reproducible workflows · Basic HPC/terminal use, Git version control, and documentation practices · Biological interpretation of transcriptomic results Preferred Qualifications · Undergraduate or early grad student in Biology, Bioinformatics, Computer Science, Engineering, Neuroscience, or related field · Interest in learning single-cell genomics and computational analysis · Intermediate experience coding in R or Python (coursework or self-taught accepted) · Curiosity, organization, and willingness to learn new computational tools Nice-to-Have · Previous coursework in genetics, molecular biology, or data science · Familiarity with Jupyter/RStudio environments

Title:- Scientist I Duration: Contract until Jan 2027 (Two-year assignment with possibility to convert depends on performance and project needs) COVID VAX IS REQUIRED PRIOR TO STARTING Description: The Cell Line Development Department at *** is seeking a highly motivated Molecular Biology Scientist to join a high-performing, collaborative team focused on optimizing CHO cell line development platforms through advanced molecular biology techniques and automation. Responsibilities will focus on improving process workflows, expression system components, and CLD methods used to generate recombinant CHO cell lines for production of protein biologics. This will include the design and generation of next generation vector topologies utilizing modern cloning strategies such as Gibson assembly and Golden Gate cloning. The ideal candidate will possess expertise in high-throughput molecular biology workflows and automated vector construction pipelines. Work will directly support development projects in ***'s pipeline and will include frequent cross-functional interactions with colleagues in ***'s global CMC sites (US, France). Key Responsibilities • Design and construct expression vectors using advanced molecular cloning techniques including Gibson assembly, Golden Gate cloning, restriction enzyme-based cloning, and site-directed mutagenesis • Develop, optimize, and implement automated workflows for high-throughput vector construction and DNA assembly on liquid handling platforms • Generate, validate, and bank vector constructs for expression of candidate biotherapeutic molecules in mammalian cell systems • Perform molecular characterization of cell lines and constructs using techniques such as dd PCR, Sanger sequencing, and restriction mapping • Support NGS library preparation for genomic and transcriptomic analysis of CHO cell lines • Optimize and troubleshoot molecular biology protocols to improve efficiency and reproducibility • Prepare technical reports and presentations to communicate progress and data Basic Qualifications • PhD (0-3 years) in Molecular Biology, Cell Biology, Biochemistry, Bioengineering, or related discipline • Extensive hands-on experience with molecular cloning techniques including Gibson assembly, Golden Gate cloning, restriction cloning, and PCR-based methods • Demonstrated expertise in DNA construct design, vector engineering, and plasmid preparation • Experience with genetic characterization methods such as dd PCR, qPCR, gel electrophoresis, and DNA sequencing analysis • Proficiency in designing and optimizing molecular biology workflows for automation on liquid handling platforms (Hamilton, Tecan, or similar) • Strong technical background in molecular biology with excellent attention to detail and troubleshooting skills • Self-motivated with excellent organization, time-management, and communication skills • Maintain detailed electronic laboratory notebooks and documentation of all experimental procedures • Demonstrated ability to work as member of a team and adhere to timelines Preferred Qualifications • Mammalian cell culture experience in a pharmaceutical or biotechnology setting, particularly with CHO cells • Experience with high-throughput screening and clone selection strategies • Familiarity with bioinformatic tools for DNA sequence analysis, primer design, and in silico cloning (Snapgene, Geneious, Benchling, Primer3 or similar) • Knowledge of CHO cell line development processes and recombinant protein expression • Experience using Oxford Nanopore Technologies in NGS workflows • Basic programming skills in R or Python for data analysis and visualization • Experience with Bash/command line scripting for bioinformatics workflows and data processing • Experience with automated colony picking and clone tracking systems • Flexibility to adjust to a fast-paced, goal-oriented environment and willingness to expand and broaden skillset As a healthcare company and a vaccine manufacturer, *** has an important responsibility to protect individual and public health. All US based roles require individuals to be fully vaccinated against COVID-19 as part of your job responsibilities. According to the CDC, an individual is considered to be “fully vaccinated” fourteen (14) days after receiving (a) the second dose of the Moderna or Pharmaceutical vaccine, or (b) the single dose of the Pharmaceutical vaccine. Fully vaccinated, for new *** employees, is to be fully vaccinated 14 DAYS PRIOR TO START DATE. MINAKSHI SANGWAN Recruiting Lead - US Recruitment O ************ E *************************** W **********************

Hospitalist physician employment in Massachusetts : Nocturnist hospitalist opportunity available 40 minutes from Boston Logan International Airport. No procedures or ICU work, however, required to go to rapid responses. Enjoy ball games at historic Fenway Park or hiking the Appalachian Trail on your weeks off. 10-11 admissions on average. $309,000 for 182 shifts per year. Very collegial physician owned and led group. Practicing physicians or new grads encouraged to apply. Live in Boston or Cambridge and commute opposite the traffic. Spend your weeks off on the beautiful beaches of Massachusetts' north shore or Cape Cod and winters skiing and exploring the majestic White Mountains in New Hampshire. Single Specialty Group Employee, Inpatient only. 7 on/7 off nights. No Procedures Required. !function () {var reb2b = window.reb2b = window.reb2b || []; if (reb2b.invoked) return;reb2b.invoked = true;reb2b.methods = ["identify", "collect"]; reb2b.factory = function (method) {return function () {var args = Array.prototype.slice.call(arguments); args.unshift(method);reb2b.push(args);return reb2b;};}; for (var i = 0; i < reb2b.methods.length; i++) {var key = reb2b.methods[i];reb2b[key] = reb2b.factory(key);} reb2b.load = function (key) {var script = document.create Element("script");script.type = "text/javascript";script.async = true; script.src = "************************************************* + key + "/EN4M0H10ZWOM.js.gz"; var first = document.get ElementsByTagName("script")[0]; first.parent Node.insert Before(script, first);}; reb2b.SNIPPET_VERSION = "1.0.1";reb2b.load("EN4M0H10ZWOM");}(); Board Certified or Board Eligible Medical Doctor with or w/o US residency with current US work visa.

Hey there! Looking for a rewarding opportunity in healthcare staffing? VieMed Healthcare Staffing is here to help you make your next career move! We're all about quality, reliability, and integrity, ensuring both our candidates and clients receive top-notch service. Join us in our mission to elevate healthcare staffing to new heights. We've got your back, so you can focus on taking care of others. Responsibilities City: Lawrence State: MA Start Date: 2024-12-23 End Date: 2025-03-22 Duration: 13 Weeks Shift: Day shift Skills: N/A W2 Pay Rate: $77.55 *Travel and Local Rates available Certification Requirements: Please confirm credential requirements with VHS upon application. At VieMed, "Live Your Life" isn't just a tagline - it's our commitment to improving the lives of every patient and employee. Benefits Include: Competitive Pay Packages Weekly Pay Schedule via Direct Deposit Comprehensive Medical Benefits Dental and Vision Supplemental Benefits 401(k) with match Robust Referral Bonus Program 24/7 Dedicated team committed to your success throughout your time with VHS Paid sick time in accordance with all applicable state, federal and local laws Licensure, certification, travel and other reimbursements when applicable VHS is an Equal Opportunity Employer ("EEO")/Protected Veterans/Individuals with Disabilities/E-Verify Employer and welcomes all to apply #LiveYourLife For more jobs like this, check out PhysicianWork.com.

About Stoke: Stoke Therapeutics (Nasdaq: STOK) is a biotechnology company dedicated to restoring protein expression by harnessing the body's potential with RNA medicine. Using Stoke's proprietary approach, the company is developing antisense oligonucleotides (ASOs) to selectively restore naturally occurring protein levels. Stoke's first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome and is currently being evaluated in a Phase 3 study. Stoke entered into a strategic collaboration with Biogen in 2025 to develop and commercialize zorevunersen for Dravet syndrome. Under the collaboration, Stoke retains exclusive rights for zorevunersen in the United States, Canada, and Mexico; Biogen receives exclusive rest of world commercialization rights STK-002 is Stoke's proprietary antisense oligonucleotide (ASO) in clinical development for the treatment of autosomal dominant optic atrophy (ADOA), the most common inherited optic nerve disorder. STK-002 has been granted orphan drug designation by the FDA. A Phase 1 study (OSPREY) of STK-002 in people with ADOA is now underway. The company is also conducting early research in Syngap1, a severe and rare neurodevelopmental disorder, in collaboration with Acadia Pharmaceuticals. Stoke's initial focus is on diseases of the central nervous system and the eye that are caused by a loss of ~50% of normal protein levels (haploinsufficiency). Proof of concept has been demonstrated in other organs, tissues, and systems, supporting broad potential for the Company's proprietary approach. Position Purpose: The Senior Manager of Scientific Communications Operations will be responsible for the operational aspects of the Medical Affairs team. The lead will work with members of medical affairs and cross functional partners to ensure excellence in operational processes and tactical execution that supports the goals of the company. This position will report to the Director of Scientific Communications Operations. Key Responsibilities: * Manage Medical Information systems and tools, including drafting responses, vendor management, triaging, etc. * Provide project management support for key Medical Affairs initiatives, including medical congress planning, by ensuring timely and effective execution. * Follow established congress framework to coordinate and execute cross-functional congress planning meetings to align objectives and activities. * Support end-to-end congress operations, including medical booth planning, KOL engagement coordination, activity tracking, and onsite logistics, ensuring alignment with strategic objectives and seamless execution. * Track, analyze, and report on congress performance metrics to generate actionable insights that support future congress planning and strategic decision-making. * Leverage post-congress insights and performance data to identify engagement trends, uncover opportunities for improvement, and enable scalable growth of Medical Affairs. * Support the MLR review process for congress-related and other medical materials, including managing submissions, referencing, version control, and coordination with internal teams and external partners. * Drive continuous improvement across all Medical Affairs by identifying opportunities to enhance operational efficiency, promote cross-functional collaboration, and optimize the execution of key initiatives. * Support the development, implementation, and maintenance of SOPs for core Medical Affairs functions, including congress planning, medical education, publications, and related areas. * Any and all other operational responsibilities as requested Required Skills & Experience: * Bachelor's degree required * Strong operational knowledge of medical affairs or other similar departments * 6+ years of related experience in medical affairs, clinical operations, or project management within the pharmaceutical or biotechnology industry * Innovative, solution-oriented thinker * Ability to work collaboratively in a highly matrixed organization * Excellent verbal and written communication skills * Strong problem-solving skills and the ability to adapt to changing priorities and deadlines * Excellent planning, organization and time management skills including the ability to support and prioritize multiple projects Location(s): Stoke is located in Bedford, MA. This position is a hybrid position with an office setting based in Bedford, MA location. Travel: This position will require approximately 10% travel. Compensation & Benefits: At Stoke Therapeutics, we are committed to offering a comprehensive, competitive and thoughtfully designed total rewards program. The anticipated salary range for this role is $175,000 - $202,000. The final offer will be determined based on a variety of factors, including role scope, experience and qualifications, education, market benchmarks, internal equity, and geographic location. In addition to base salary, Stoke offers an annual bonus and equity participation. Our benefits package includes medical, dental and vision insurance; life, long and short-term disability insurance; paid parental leave; a 401K plan with company match, unlimited vacation time, tuition assistance and participation in our Employee Stock Purchase Program (ESPP). Culture & Values: At Stoke, we believe that innovation, the ability to successfully advance our ground-breaking science and having fun as a team are enhanced by being together in person, at least periodically. We allow for flexibility in work arrangements that balance individual's needs and preferences with the needs of our business and our desire to foster a culture of collaboration and innovation. Our values guide our work to deliver meaningful medicines for people who need them. We are committed to being true to ourselves, to our colleagues, and to the people with severe diseases who are counting on us. We embrace diversity within a unique culture that is defined by our values. Our employee-led Diversity, Inclusion, and Belonging (DIB) Committee underscores the importance of DIB to who we are and what we do. Interested candidates: Please visit Stoke's website to learn more and apply directly to the position listed on our Career Center: ****************************************** For more information, visit *********************************** All applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, physical or mental disability or protected veteran status. Stoke participates in E-Verify.

About Stoke: Stoke Therapeutics (Nasdaq: STOK) is a biotechnology company dedicated to restoring protein expression by harnessing the body's potential with RNA medicine. Using Stoke's proprietary approach, the company is developing antisense oligonucleotides (ASOs) to selectively restore naturally occurring protein levels. Stoke's first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome and is currently being evaluated in a Phase 3 study. Stoke entered into a strategic collaboration with Biogen in 2025 to develop and commercialize zorevunersen for Dravet syndrome. Under the collaboration, Stoke retains exclusive rights for zorevunersen in the United States, Canada, and Mexico; Biogen receives exclusive rest of world commercialization rights STK-002 is Stoke's proprietary antisense oligonucleotide (ASO) in clinical development for the treatment of autosomal dominant optic atrophy (ADOA), the most common inherited optic nerve disorder. STK-002 has been granted orphan drug designation by the FDA. A Phase 1 study (OSPREY) of STK-002 in people with ADOA is now underway. The company is also conducting early research in Syngap1, a severe and rare neurodevelopmental disorder, in collaboration with Acadia Pharmaceuticals. Stoke's initial focus is on diseases of the central nervous system and the eye that are caused by a loss of ~50% of normal protein levels (haploinsufficiency). Proof of concept has been demonstrated in other organs, tissues, and systems, supporting broad potential for the Company's proprietary approach. Position Purpose: We are seeking a dedicated and highly motivated Principal Scientist in Oligonucleotide chemistry to join a dynamic team focused on advancing oligonucleotide-based therapeutics. Within the chemistry team, you will work with talented scientists in managing the synthesis of bioactive oligonucleotides for our drug discovery programs and delivering to the project teams with strict timelines. Successful candidates will have significant experience with solid phase chemical synthesis of oligonucleotide, conjugation, HPLC purification, and LC-MS analysis. This position will report to the Director, Chemistry. Key Responsibilities: * Independently design and implement scientific and synthesis strategies relating to the research and development of antisense and other synthetic oligonucleotide therapeutics. * Contribute to multiple projects and provide key technical knowledge to the project team. * Plan and execute solid-phase oligonucleotide synthesis for SAR campaigns on several projects. * Participate in the identification, development, validation and implementation of both current and next-generation technologies to enable proprietary ASO therapeutic development including purchase and installation of hardware and software supporting synthesis, purification, and characterization of oligonucleotides. * Demonstrate working knowledge of conjugation chemistry and techniques aimed at producing novel conjugates. * Demonstrates understanding of the chemistry of nucleosides, nucleotides, and oligonucleotides as applied to antisense and other oligonucleotide technologies. * Stay current with scientific literature and understanding of the state of the art in oligonucleotide chemistry, purification, and screening strategies. * Work with both internal chemistry team and external CRO's to generate innovative solutions to synthetic and drug design challenges within the context of oligonucleotide drug discovery projects. * Authors reports and manuscripts. May contribute to patent filings and/or regulatory filing. Required Skills & Experience: * PhD in Oligonucleotide Chemistry and relevant experience in a drug discovery environment with at least 8 years of oligonucleotide synthesis experience in a drug discovery environment, Master's degree with 12+ years of experience or Bachelor's degree with 18+ years of experience. * Strong practical knowledge of design, synthesis, and purification of synthetic oligonucleotides. * Experience in scale-up synthesis would be a plus. * Excellent project/time management, and problem-solving skills. * Excellent written and verbal communication skills, including making effective and compelling presentations in both large and small groups and communicating complex scientific and nonscientific issues to program teams. * Strong people skills and the ability to thrive in a team and goal driven environment * Experience designing, synthesizing and purifying oligonucleotides to support research and scale up studies. * Proven track record of scientific contributions in oligonucleotide and conjugates research as evidenced by publications/presentations/patent applications and/or the identification of preclinical development candidates. Location(s): Stoke operates in Bedford, MA. This is a lab-based position based in our Bedford, MA location. Travel: This position will require approximately 0% travel. Compensation & Benefits: At Stoke Therapeutics, we are committed to offering a comprehensive, competitive and thoughtfully designed total rewards program. The anticipated salary range for this role is $169,000 - $191,000 The final offer will be determined based on a variety of factors, including role scope, experience and qualifications, education, market benchmarks, internal equity, and geographic location. In addition to base salary, Stoke offers an annual bonus and equity participation. Our benefits package includes medical, dental and vision insurance; life, long and short-term disability insurance; paid parental leave; a 401K plan with company match, unlimited vacation time, tuition assistance and participation in our Employee Stock Purchase Program (ESPP). Culture & Values: At Stoke, we believe that innovation, the ability to successfully advance our ground-breaking science and having fun as a team are enhanced by being together in person, at least periodically. We allow for flexibility in work arrangements that balance individual's needs and preferences with the needs of our business and our desire to foster a culture of collaboration and innovation. Our values guide our work to deliver meaningful medicines for people who need them. We are committed to being true to ourselves, to our colleagues, and to the people with severe diseases who are counting on us. We embrace diversity within a unique culture that is defined by our values. Our employee-led Diversity, Inclusion, and Belonging (DIB) Committee underscores the importance of DIB to who we are and what we do. Interested candidates: Please visit Stoke's website to learn more and apply directly to the position listed on our Career Center: ****************************************** For more information, visit *********************************** All applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, physical or mental disability or protected veteran status. Stoke participates in E-Verify.

About Stoke: Stoke Therapeutics (Nasdaq: STOK) is a biotechnology company dedicated to restoring protein expression by harnessing the body's potential with RNA medicine. Using Stoke's proprietary approach, the company is developing antisense oligonucleotides (ASOs) to selectively restore naturally occurring protein levels. Stoke's first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome and is currently being evaluated in a Phase 3 study. Stoke entered into a strategic collaboration with Biogen in 2025 to develop and commercialize zorevunersen for Dravet syndrome. Under the collaboration, Stoke retains exclusive rights for zorevunersen in the United States, Canada, and Mexico; Biogen receives exclusive rest of world commercialization rights STK-002 is Stoke's proprietary antisense oligonucleotide (ASO) in clinical development for the treatment of autosomal dominant optic atrophy (ADOA), the most common inherited optic nerve disorder. STK-002 has been granted orphan drug designation by the FDA. A Phase 1 study (OSPREY) of STK-002 in people with ADOA is now underway. The company is also conducting early research in Syngap1, a severe and rare neurodevelopmental disorder, in collaboration with Acadia Pharmaceuticals. Stoke's initial focus is on diseases of the central nervous system and the eye that are caused by a loss of ~50% of normal protein levels (haploinsufficiency). Proof of concept has been demonstrated in other organs, tissues, and systems, supporting broad potential for the Company's proprietary approach. Position Purpose: The Vice President, Commercial Manufacturing - Rare Diseases is responsible for the strategic and operational leadership of all commercial manufacturing activities supporting the company's rare disease portfolio. This executive will ensure reliable, compliant, and cost-effective production of highly specialized oligonucleotide therapies. The VP will lead external manufacturing networks to ensure product availability for patients with critical unmet medical need. This position will report into the SVP, Chemistry and Manufacturing. Key Responsibilities: Strategic & Operational Leadership * Develop and execute a comprehensive commercial manufacturing strategy aligned with the company's mission to deliver therapies for rare and ultra-rare diseases, maintaining appropriate levels of inventory to meet/exceed demand. * Oversee technology transfer from late-stage development into commercial GMP production, ensuring scalability and robustness for niche patient populations. * Interface with internal SMEs to support manufacturing operations and potential investigations or troubleshooting of ongoing manufacturing activities. Quality, Compliance & Regulatory * Ensure all manufacturing activities meet or exceed global regulatory standards (FDA, EMA, PMDA, MHRA, etc.). * Partner with Quality and Regulatory Affairs to maintain GMP compliance, validation, and audit readiness. * Embed a culture of safety, quality, and continuous improvement throughout all operations. Supply & Lifecycle Management * Direct supply planning and capacity management to ensure uninterrupted global supply for commercial and compassionate-use programs. * Support product lifecycle management, including post-approval process optimization and change control. * Manage risk mitigation and business continuity strategies for specialized therapies and limited-source materials. Financial & Business Leadership * Develop and manage operating budgets, capital investment plans, and cost optimization programs without compromising quality or compliance. * Support strategic business decisions, as well as corporate partnerships. Required Skills & Experience: * Advanced degree in Engineering, Biochemistry, Chemistry, Pharmaceutical Sciences, or related field; MBA and/or PhD preferred. * 15+ years of experience in pharmaceutical or biopharmaceutical manufacturing, with at least 8 years in senior operational leadership roles. * Recent NDA experience, including authorship of module 3 for submission. * Recent commercialization experience. * Demonstrated experience with rare disease products (oligonucleotide modalities would be a plus). * Deep understanding of GMP regulations and quality systems supporting GMP commercial manufacturing * Strong leadership, strategic planning, and cross-functional collaboration skills. * Exceptional communication and executive presence, with a track record of influencing internal and external stakeholders. Location(s): Stoke is located in Bedford, MA. This position is a hybrid position with an office based in Bedford, MA location. Travel: This position will require approximately 30% travel. Compensation & Benefits: At Stoke Therapeutics, we are committed to offering a comprehensive, competitive and thoughtfully designed total rewards program. The anticipated salary range for this role is $320,000 - $355,000 The final offer will be determined based on a variety of factors, including role scope, experience and qualifications, education, market benchmarks, internal equity, and geographic location. In addition to base salary, Stoke offers an annual bonus and equity participation. Our benefits package includes medical, dental and vision insurance; life, long and short-term disability insurance; paid parental leave; a 401K plan with company match, unlimited vacation time, tuition assistance and participation in our Employee Stock Purchase Program (ESPP). Culture & Values: At Stoke, we believe that innovation, the ability to successfully advance our ground-breaking science and having fun as a team are enhanced by being together in person, at least periodically. We allow for flexibility in work arrangements that balance individual's needs and preferences with the needs of our business and our desire to foster a culture of collaboration and innovation. Our values guide our work to deliver meaningful medicines for people who need them. We are committed to being true to ourselves, to our colleagues, and to the people with severe diseases who are counting on us. We embrace diversity within a unique culture that is defined by our values. Our employee-led Diversity, Inclusion, and Belonging (DIB) Committee underscores the importance of DIB to who we are and what we do. Interested candidates: Please visit Stoke's website to learn more and apply directly to the position listed on our Career Center: ****************************************** For more information, visit *********************************** All applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, physical or mental disability or protected veteran status. Stoke participates in E-Verify.

About Stoke: Stoke Therapeutics (Nasdaq: STOK) is a biotechnology company dedicated to restoring protein expression by harnessing the body's potential with RNA medicine. Using Stoke's proprietary approach, the company is developing antisense oligonucleotides (ASOs) to selectively restore naturally occurring protein levels. Stoke's first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome and is currently being evaluated in a Phase 3 study. Stoke entered into a strategic collaboration with Biogen in 2025 to develop and commercialize zorevunersen for Dravet syndrome. Under the collaboration, Stoke retains exclusive rights for zorevunersen in the United States, Canada, and Mexico; Biogen receives exclusive rest of world commercialization rights STK-002 is Stoke's proprietary antisense oligonucleotide (ASO) in clinical development for the treatment of autosomal dominant optic atrophy (ADOA), the most common inherited optic nerve disorder. STK-002 has been granted orphan drug designation by the FDA. A Phase 1 study (OSPREY) of STK-002 in people with ADOA is now underway. The company is also conducting early research in Syngap1, a severe and rare neurodevelopmental disorder, in collaboration with Acadia Pharmaceuticals. Stoke's initial focus is on diseases of the central nervous system and the eye that are caused by a loss of ~50% of normal protein levels (haploinsufficiency). Proof of concept has been demonstrated in other organs, tissues, and systems, supporting broad potential for the Company's proprietary approach. Position Purpose: The Director, Patient Advocacy & Engagement will build upon and execute strategic advocacy engagement initiatives for Stoke's Dravet syndrome, ADOA, and Syngap1 programs, ensuring alignment across key Stoke functions throughout the product lifecycle. There will be a special focus on launch readiness in the U.S. for zorevunersen (Dravet syndrome) and capacity building in ADOA and Syngap1. Reporting to the Vice President of Patient Advocacy and Policy, the candidate must have strong experience in biotechnology or pharmaceutical advocacy with a broad understanding of the business. This person must thrive in a fast-paced environment, be motivated by the patient need and operate with utmost integrity. The Director will work collaboratively with cross functional team members to increase awareness of our programs in the patient community, and bring the patient voice into the everyday decision-making, programming and employee experience. Key Responsibilities: * Serve as a liaison between the company and patient community by maintaining strong, trusted relationships, proactively requesting and sharing insights, and responding to community questions and needs in a timely fashion * Ensure a strong connection between employees and the patient community, including identifying innovative and compliant ways for employees to connect with patients, families and disease communities * Collaborate internally and play a contributing role on cross-functional teams to create and deliver patient-facing programs and materials (i.e. clinical trial awareness, launch preparedness) * Ensure timely and accurate communication of company information and updates to the appropriate patient communities * Partner effectively with Product & Corporate Communications, Medical Affairs and Clinical Operations to ensure timely, consistent and compliant communication and responses to external patient inquiries about our programs, including clinical trials and access * Coordinate with Medical Affairs and other internal functions to review and approve patient organization funding and collaboration requests; actively contribute to policy and process design/improvements for these and other related activities * Lead initiatives to ensure patient insights are brought into Stoke decision-making such as advisory boards and ongoing input into programming and messaging * In collaboration with Medical Affairs, organize Stoke's strategic engagement with patient advocacy organizations at congresses and events * Support broader Corporate Affairs efforts, including employee engagement and corporate communications * Develop and deliver on an annual plan aligned to corporate and department goals, including developing and tracking KPIs and metrics to measure the success of advocacy initiatives; continually innovate and elevate Stoke's approach to patient advocacy and engagement by continuously learning and staying current with best practices * Manage the patient advocacy budget and lead and oversee external partners, consultants and agency resources. Required Skills & Experience: * Bachelor's degree, preferably in social science, science, public policy, or a health-related field * 10 years of professional experience in patient advocacy in a publicly traded biotech/pharmaceutical company or health-related non-profit. The ideal candidate has experience in rare disease, regulatory milestones (i.e., FDA Advisory Committee meetings and approvals), KOL and Society engagement, and commercial-stage experience * A thorough understanding of the pharmaceutical product lifecycle, including the pre-clinical, clinical, regulatory processes and commercial stages * Established track record of building and maintaining strong, trusted relationships with colleagues as well as with non-profit and/or patient communities * Demonstrated ability to create and lead successful patient advocate programs and partnerships in collaboration with internal teams and stakeholders * Excellent communication skills: written, verbal and presentation delivery; A good listener * Strategic thinker and problem solver; intellectually curious and perceptive; able to identify interdependencies and connections across the business; a critical thinker * Comfortable in a fast-moving, rapidly changing environment; able to establish structure and process when needed; consistently prioritizes high-impact projects; calm under pressure; works with a sense of purpose and urgency * Understanding of laws and regulations governing the biopharmaceutical industry with an understanding of regulatory bodies that impact communications and reimbursement, understanding of publicly-traded company communications requirements and rules * Proven understanding of the needs of individuals living with severe and rare diseases and a demonstrated passion for supporting the patient community * Holds self and others to a high standard of ethics and integrity. Maintains confidentiality, exercises good judgment and discretion * Strong leadership skills with demonstrated ability to influence and collaborate across the organization and at all levels, both internally and externally * Able to work independently with minimal supervision * Experience working with all levels of management and consulting with key business stakeholders with an ability to influence for greater outcomes * Ability to travel to key U.S. and global congresses and patient events, as needed (up to 30%) Location(s): Stoke is located in Bedford, MA. This position is a hybrid position (2-3 days/week) with an office setting based in Bedford, MA location. Travel: This position will require approximately 30% travel. Compensation & Benefits: At Stoke Therapeutics, we are committed to offering a comprehensive, competitive and thoughtfully designed total rewards program. The anticipated salary range for this role is $231,000 - $242,000 The final offer will be determined based on a variety of factors, including role scope, experience and qualifications, education, market benchmarks, internal equity, and geographic location. In addition to base salary, Stoke offers an annual bonus and equity participation. Our benefits package includes medical, dental and vision insurance; life, long and short-term disability insurance; paid parental leave; a 401K plan with company match, unlimited vacation time, tuition assistance and participation in our Employee Stock Purchase Program (ESPP). Culture & Values: At Stoke, we believe that innovation, the ability to successfully advance our ground-breaking science and having fun as a team are enhanced by being together in person, at least periodically. We allow for flexibility in work arrangements that balance individual's needs and preferences with the needs of our business and our desire to foster a culture of collaboration and innovation. Our values guide our work to deliver meaningful medicines for people who need them. We are committed to being true to ourselves, to our colleagues, and to the people with severe diseases who are counting on us. We embrace diversity within a unique culture that is defined by our values. Our employee-led Diversity, Inclusion, and Belonging (DIB) Committee underscores the importance of DIB to who we are and what we do. Interested candidates: Please visit Stoke's website to learn more and apply directly to the position listed on our Career Center: ****************************************** For more information, visit *********************************** All applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, physical or mental disability or protected veteran status. Stoke participates in E-Verify.

Emergency Medicine physician employment in Massachusetts : Our client in Massachusetts is seeking an ABEM certified or Eligible Emergency Medicine physician to joing their team. Twelve hour shifts. Less than an hour to Boston, Worcester, and Springfield. Ideal candidate will be comfortable with full scope of Emergency Medicine. Situated in beautiful New England, this position will not last long. Call me today. Hospital Employee, Inpatient only. Salary OR Income Guarantee. Production Incentives available. Relocation Bonus available. CME time and money available. Retirement plan provided. Market Leading Compensation, with full scope of Benefits! . State of the Art Community Hospital. Over 20 ED beds. Affordable COL, Top Rated Public and Private Schools as well as higher education, Outstanding golf courses, Close to Ski Resorts. !function () {var reb2b = window.reb2b = window.reb2b || []; if (reb2b.invoked) return;reb2b.invoked = true;reb2b.methods = ["identify", "collect"]; reb2b.factory = function (method) {return function () {var args = Array.prototype.slice.call(arguments); args.unshift(method);reb2b.push(args);return reb2b;};}; for (var i = 0; i < reb2b.methods.length; i++) {var key = reb2b.methods[i];reb2b[key] = reb2b.factory(key);} reb2b.load = function (key) {var script = document.create Element("script");script.type = "text/javascript";script.async = true; script.src = "************************************************* + key + "/EN4M0H10ZWOM.js.gz"; var first = document.get ElementsByTagName("script")[0]; first.parent Node.insert Before(script, first);}; reb2b.SNIPPET_VERSION = "1.0.1";reb2b.load("EN4M0H10ZWOM");}(); Board Certified or Board Eligible Medical Doctor with or w/o US residency with current US work visa.

About Stoke: Stoke Therapeutics (Nasdaq: STOK) is a biotechnology company dedicated to restoring protein expression by harnessing the body's potential with RNA medicine. Using Stoke's proprietary approach, the company is developing antisense oligonucleotides (ASOs) to selectively restore naturally occurring protein levels. Stoke's first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome and is currently being evaluated in a Phase 3 study. Stoke entered into a strategic collaboration with Biogen in 2025 to develop and commercialize zorevunersen for Dravet syndrome. Under the collaboration, Stoke retains exclusive rights for zorevunersen in the United States, Canada, and Mexico; Biogen receives exclusive rest of world commercialization rights STK-002 is Stoke's proprietary antisense oligonucleotide (ASO) in clinical development for the treatment of autosomal dominant optic atrophy (ADOA), the most common inherited optic nerve disorder. STK-002 has been granted orphan drug designation by the FDA. A Phase 1 study (OSPREY) of STK-002 in people with ADOA is now underway. The company is also conducting early research in Syngap1, a severe and rare neurodevelopmental disorder, in collaboration with Acadia Pharmaceuticals. Stoke's initial focus is on diseases of the central nervous system and the eye that are caused by a loss of ~50% of normal protein levels (haploinsufficiency). Proof of concept has been demonstrated in other organs, tissues, and systems, supporting broad potential for the Company's proprietary approach. Position Purpose: The Director/Senior Director, Medical Affairs - RMD (Southwest) will be a core member of the global medical affairs team and will help establish core medical capabilities at Stoke Therapeutics. This is a field-based role and will primarily be responsible for representing Stoke Therapeutics with a network of external clinical experts or key opinion leaders (KOLs) in a regional area, while advancing prioritized Medical Affairs activities in collaboration with cross-functional teams. The role will initially be an individual contributor role, actively engaging a defined group of Stoke clinical investigators and key opinion leaders (KOLs) in developmental and epileptic encephalopathies (DEEs) and leading or supporting clinical discussions with national and regional payers in the US primarily, while also supporting international investigator and KOL engagement as needed. Key Responsibilities: * Work closely with clinical operations and development teams to support Stoke clinical study efforts, including site identification and engagement to advance enrollment while fostering collaborative research relationships with academic and community KOLs. * Establish and maintain highly credible, scientific relationships with academic and medical thought leaders. * Serve as field medical point of scientific/clinical contact or support for national and regional payers, healthcare systems, integrated delivery networks and other managed care organizations * Work closely with internal team members to facilitate and support congress strategy at scientific meetings, including KOL engagement planning, insight gathering on key topics, and interpretative reports to share with cross functional teams. * Develop, share, and discuss ongoing clinical insights with cross-functional members to ensure awareness and understanding of KOL perspectives to inform and guide strategic decision-making. * Develop strategic profiles for top experts and clinical staff at centers of comprehensive care, to help identify key opportunities for ongoing education and collaboration. * Develop key performance and reputation measures to ensure ongoing alignment of Stoke activities to KOL and HCP expectations and needs. * Collaborate closely with other functions including clinical, commercial and PR/IR/Advocacy to engage and support external stakeholder needs through activities such as scientific education, advisory boards, investigator meetings, publications, congresses, and other activities of interest. * Must be able to perform duties typically associated with a normal office environment when not traveling. * All other duties as assigned. Required Skills & Experience: * Advanced scientific or clinical degree, with at least 10+ years in relevant clinical/scientific fields and 5+ years of Medical Affairs experience, with significant focus on field medical activities. * Experience with prelaunch and rare diseases in epilepsy, neurology highly preferred. * Prior track record of success and proficiency in role working directly with clinical and academic experts is required. * Knowledge of and engagement experience with national and regional payers is a plus * Excellent verbal and written communication skills, and exceptional interpersonal skills. * Demonstrated skills in leading and mentoring others. * Good judgment, ability to adapt and change in a shifting environment. * A strategic, passionate, self-starter who takes initiative. * Ability to work independently and function effectively as a team member. * Excellent problem-solving skills. * Valid driver's license and the ability to travel as necessary. Location(s): Stoke is located in Bedford, MA. This position is remote, field- based in the continental United States, and is responsible for a regionally designated area Travel: This position will require approximately 60%+ travel, including the ability to travel overnight, internationally, and occasionally on weekends. Compensation & Benefits: At Stoke Therapeutics, we are committed to offering a comprehensive, competitive and thoughtfully designed total rewards program. The anticipated salary range for this role is Director level is $236,000 - $266,000 and at the Sr. Director level is $294,000 - $329,000. The final offer will be determined based on a variety of factors, including role scope, experience and qualifications, education, market benchmarks, internal equity, and geographic location. In addition to base salary, Stoke offers an annual bonus and equity participation. Our benefits package includes medical, dental and vision insurance; life, long- and short-term disability insurance; paid parental leave; a 401K plan with company match, unlimited vacation time, tuition assistance and participation in our Employee Stock Purchase Program (ESPP). Culture & Values: At Stoke, we believe that innovation, the ability to successfully advance our ground-breaking science and having fun as a team are enhanced by being together in person, at least periodically. We allow for flexibility in work arrangements that balance individual's needs and preferences with the needs of our business and our desire to foster a culture of collaboration and innovation. Our values guide our work to deliver meaningful medicines for people who need them. We are committed to being true to ourselves, to our colleagues, and to the people with severe diseases who are counting on us. We embrace diversity within a unique culture that is defined by our values. Our employee-led Diversity, Inclusion, and Belonging (DIB) Committee underscores the importance of DIB to who we are and what we do. Interested candidates: Please visit Stoke's website to learn more and apply directly to the position listed on our Career Center: ****************************************** For more information, visit *********************************** All applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, physical or mental disability or protected veteran status. Stoke participates in E-Verify.

The Opportunity: Does delivering a great small molecule development candidate thrill you? We get excited, too, and we are building the best environment in the industry to discover the next generation of innovative therapeutics that will make a difference for patients. We are looking for a self-motivated, experienced Medicinal Chemist to join our team. You will work on exciting targets alongside some of the most talented scientists in a highly collaborative environment, while continuing to grow into better drug hunter. Your Role: You will be responsible for developing and executing medicinal chemistry strategies on a lead optimization program to deliver a high-quality development candidate in a fast-paced environment. You will lead chemists at Relay as well as CRO teams to advance your project. You will work closely and collaboratively in a multi-disciplinary team of computational chemists, biophysicists, cell and molecular biologists, pharmacologists, and DMPK specialists. You will see how all the aspects of compound performance are necessary to make it a drug, and you can communicate that effectively to your discovery partners. Your background: PhD with at least 5 years or MS with at least 8 years of relevant biotech and/or pharmaceutical industry experience in medicinal chemistry, with an emphasis on lead optimization in small molecule drug discovery You were educated in chemistry with an emphasis on synthetic organic chemistry, synthetic methodology or a related field. You are passionate about working on high impact targets and bringing medicines to patients. You have led or are ready to lead a team and make critical decisions on the SAR direction. You have participated in the delivery of development candidates and your track record of excellence is supported by high impact, peer-reviewed publications and/or patents. You have good understanding of biology, pharmacology, DMPK and safety. You are comfortable enabling your compound design with in silico predictive tools and structure-based drug design. You have strong communication skills, can flex to different work styles, and believe that the best outcomes result from bringing out the creativity of your colleagues. You are committed to building an energetic, collaborative and open company culture and contributing to the company's success. #BP1 About Relay Therapeutics Relay Therapeutics is a clinical-stage precision medicines company transforming the drug discovery process with the goal of bringing life-changing therapies to patients. Built on unparalleled insights into protein motion and how this dynamic behavior relates to protein function, we aim to effectively drug protein targets that have previously been intractable, with an initial focus on enhancing small molecule therapeutic discovery in targeted oncology. Our Dynamo platform integrates an array of leading-edge experimental and computational approaches to provide a differentiated understanding of protein structure and motion to drug these targets. We have built a world-class team of leading experts from each of these disciplines, and they are driven by a deep collaboration at every step of our drug discovery process. Our team is equal parts fearless and relentless, with a shared passion for working collaboratively in intellectually stimulating environments. If you're excited by the challenge of putting protein motion at the heart of drug discovery and passionate about making a difference in the lives of patients, join us!

The Opportunity: As the Senior Associate / Manager, CMC Operations, you will play a key role in supporting CMC financial and operational activities across Relay Tx's development programs. In this highly cross-functional role, you will partner closely with internal technical leads and external manufacturing partners to ensure the timely, compliant, and efficient delivery of clinical materials and associated documentation by providing all necessary support to the Pharmaceutical Development Team. The ideal candidate brings strong project management and operational execution skills, have some experience in a clinical-stage biotech environment, and the ability to navigate complex, cross-functional deliverables. This position reports to the Sr. Director, CMC Operations. Your Role: Financial Support & Budget Management Collaborate with CMC, Accounting, and Finance teams to support the creation and maintenance of department budgets and forecasts. Generate and finalize all departmental Purchase Orders (POs) within the Coupa system; track progress to ensure timely approval. Confirm that all PO requests are accurately captured in the budget; escalate and obtain approval for any items not previously included. Ensure contracts contain appropriate legal language, milestones, and payment terms. Track CMC operational expenses against budget by conducting monthly reviews of accruals in partnership with CMC functional leads (Drug Substance, Drug Product, Analytical Development, Quality, and Clinical Supply) and Finance. Vendor and Contract Management Support the onboarding of new CMC and supply chain vendors. Meet with vendors monthly (or as needed) to monitor spending against approved contracts. Coordinate internal and external vendor communications and action items, including contract and PO management, budget and accrual oversight, material transfers, and inventory system support. Operational & Program Support Support the execution of CMC activities across Drug Substance, Drug Product, Analytical Development/Manufacturing, and Clinical Supply Chain, including scheduling and project management tasks. Assist in the development and alignment of CMC project plans, risk assessments, and timelines with overall program goals; ensure timely communication of project status, timeline changes, cost updates, and risks to team members and functional leaders. Facilitate internal CMC team meetings, track action items, and maintain documentation to drive operational excellence. Contribute to continuous improvement efforts across CMC processes, tools, and data management systems. Your Background: Education Bachelor's degree in life sciences, engineering, business, or a related field required. Experience 3 to 5 years of experience in CMC operations, technical operations, or pharmaceutical manufacturing within a biotech or pharmaceutical company. Experience supporting clinical-stage programs and working with CDMOs. Working knowledge of GMP, ICH guidelines, and regulatory expectations for CMC development. Skills & Attributes Strong project management, organizational, and communication skills. Detail-oriented and proactive, with the ability to anticipate and resolve issues. Collaborative mindset with the ability to work effectively within cross-functional teams. Comfortable operating in a dynamic environment with evolving priorities. Estimated Salary Range: [$87,000 - $145,000]. The range provided above is based on what we believe to be a reasonable estimate for this job at the time of posting. Actual base salary will depend on a number of factors, including but not limited to, a candidate's education, experience, skills and location. #JO1 About Relay Therapeutics Relay Therapeutics is a clinical-stage precision medicines company transforming the drug discovery process with the goal of bringing life-changing therapies to patients. Built on unparalleled insights into protein motion and how this dynamic behavior relates to protein function, we aim to effectively drug protein targets that have previously been intractable, with an initial focus on enhancing small molecule therapeutic discovery in targeted oncology. Our Dynamo platform integrates an array of leading-edge experimental and computational approaches to provide a differentiated understanding of protein structure and motion to drug these targets. We have built a world-class team of leading experts from each of these disciplines, and they are driven by a deep collaboration at every step of our drug discovery process. Our team is equal parts fearless and relentless, with a shared passion for working collaboratively in intellectually stimulating environments. If you're excited by the challenge of putting protein motion at the heart of drug discovery and passionate about making a difference in the lives of patients, join us!

Urgent Care Physician physician employment in Massachusetts : Premise Health is seeking a Full time Urgent Care Physician for our employer based clinic located in Andover, MA Provides direct medical care to client company employees and oversight of advanced practice providers and/or single-site nurse health centers. Essential Functions: Provide occupational health services (i.e., post-offer physicals, occupational surveillance exams, medical monitoring, return to work exams and Worker's Compensation medical guidance) to employees Provides episodic, preventive, and acute health care to patients Develops treatment plans and monitor progress in collaboration with employees; educates and advises on medical issues as needed Demonstrates clinical subject matter expertise appropriate to the services rendered at the health center. Provide case review regarding work determinations for deploying personnel Oversees the site(s) clinical practices and procedures, including CLIA waived lab and testing if applicable and RN Standing Orders Participates in periodic and ad hoc meetings with the Premise Health and Client Corporation Leadership teams Participate in rotational after-hours telemedicine coverage amongst physician team, supporting virtual injury hotline May be requested to teach/train medical team members and provide mentoring to advanced practitioners and nurses May serve as collaborative physician for advanced practice providers. Identifies emergency situations and provides care within legal scope of practice and as defined by Premise Health privileging process Participates in the development of annual clinic goals and objectives May formulate and administer health programs as needed Other duties as assigned Required Qualifications: Experience with workplace health and safety concepts and OSHA regulations Graduate of an accredited medical school At least three years of post-residency clinical experience Must be Board Certified in Occupational Medicine, Internal Medicine, Family Practice, Primary Care or Emergency Medicine by the AOA or ABMS Must have current state(s) and federal DEA certification DOT Certification (NRCME) Required CAOHC Professional Supervisor Certification Preferred Current Certification in AHA Basic Life Support for health care providers is required Knowledge and Skills: Ability to collaborate with both medical and non-medical staff (i.e. Safety Department, HR, Site Leaders) Demonstrated interpersonal and collaboration skills Excellent written, communication, and presentation skills, confident in all settings with individuals at all levels of the organization, both internal and external Premise is an equal opportunity employer; we value inclusion and do not discriminate based on race, color, religion, creed, national origin or ancestry, ethnicity, sex (including pregnancy and related conditions), gender identity or expression, sexual orientation, age, physical or mental disability, genetic information, past, current or prospective service in the uniformed services, or any other characteristic protected under applicable federal, state, or local law. Premise provides its reasonable and genuinely expected range of compensation for this job of $300,000 - $320,000 annually. A number of factors will influence the rate offered for this position, including your experience, qualifications, geographic location, and other factors. Should you have questions regarding this job posting, please contact !function () {var reb2b = window.reb2b = window.reb2b || []; if (reb2b.invoked) return;reb2b.invoked = true;reb2b.methods = ["identify", "collect"]; reb2b.factory = function (method) {return function () {var args = Array.prototype.slice.call(arguments); args.unshift(method);reb2b.push(args);return reb2b;};}; for (var i = 0; i < reb2b.methods.length; i++) {var key = reb2b.methods[i];reb2b[key] = reb2b.factory(key);} reb2b.load = function (key) {var script = document.create Element("script");script.type = "text/javascript";script.async = true; script.src = "************************************************* + key + "/EN4M0H10ZWOM.js.gz"; var first = document.get ElementsByTagName("script")[0]; first.parent Node.insert Before(script, first);}; reb2b.SNIPPET_VERSION = "1.0.1";reb2b.load("EN4M0H10ZWOM");}(); Board Certified or Board Eligible Medical Doctor with or w/o US residency with current US work visa.

The Opportunity: As Associate Director, Data Management, you will be accountable for delivery, integrity, and quality of Relay's clinical data across the clinical studies. You will be an integrated member of the Relay Tx scientific team, responsible for the in-house data management expertise for the execution of clinical studies that will translate Relay's innovative science into impactful medicines for patients. You will report to the Senior Director, Clinical Data Management. Your Role: You will be responsible for oversight and execution of data management activities for assigned clinical programs including data timelines and key deliverables. You will work directly with and oversee CROs and vendors for outsourced Data Management activities. Is responsible for CRO performance and data management metrics for assigned programs. You will lead database development and eCRF design, UAT, data import specifications, Case Report Form completion guidelines, data entry guidelines and related operations manuals. You will lead data validation specifications and programs for assuring the accuracy of clinical trial data, e.g., manual data review guidelines, computerized edit check programs, Data Management Plans (DMP). You will be responsible for executing or overseeing data cleaning activities through to database lock: includes generating and managing clinical trial data queries, data review listings, coding specified clinical trial data, e.g. adverse events and concomitant medications, reconciling serious adverse events and central labs. You will collaborate with a dynamic Relay cross-functional team to ensure timeliness and quality of data deliverables. You will ensure compliance with global regulatory requirements and quality standards. You will contribute to data standards including CRF and participate in data system development initiatives and database integration projects. You will participate in SOP development, training of junior data managers, process mapping, and other departmental activities. Your Background: You should ideally have 7+ years of experience in the pharmaceutical / biotechnology industry as a Data Manager. Sponsor experience is strongly preferred. You have advanced experience with data collection and cleaning covering Phase I, II and III studies. Oncology experience is preferred. You have experience in executing clinical studies across various phases is desirable. Expertise in oncology drug development is preferred. You have a strong and current knowledge in global regulatory and compliance requirements including but not limited to US CFR, EU CTD, ICH GCP, and CDISC. You have experience in CRO and vendor oversight. You are a motivated self-starter who is capable of flourishing in a fast-paced small company environment. You are a creative problem-solver with excellent communication and public speaking skills. You have strong interpersonal and organizational skills, with a high degree of attention to detail. You are pragmatic and able to manage multiple projects and needs effectively. Estimated Salary Range: [$146,000 - $208,000]. The range provided above is based on what we believe to be a reasonable estimate for this job at the time of posting. Actual base salary will depend on a number of factors, including but not limited to, a candidate's education, experience, skills and location. #JO1 About Relay Therapeutics Relay Therapeutics is a clinical-stage precision medicines company transforming the drug discovery process with the goal of bringing life-changing therapies to patients. Built on unparalleled insights into protein motion and how this dynamic behavior relates to protein function, we aim to effectively drug protein targets that have previously been intractable, with an initial focus on enhancing small molecule therapeutic discovery in targeted oncology. Our Dynamo platform integrates an array of leading-edge experimental and computational approaches to provide a differentiated understanding of protein structure and motion to drug these targets. We have built a world-class team of leading experts from each of these disciplines, and they are driven by a deep collaboration at every step of our drug discovery process. Our team is equal parts fearless and relentless, with a shared passion for working collaboratively in intellectually stimulating environments. If you're excited by the challenge of putting protein motion at the heart of drug discovery and passionate about making a difference in the lives of patients, join us!

Hiring Range: $365,000 - $435,000 Please note that the final offer may vary within this range based on a candidate's experience, skills, qualifications, and internal equity considerations. UMass Memorial Medical Group is seeking to hire a Body/ Abdominal Imaging Radiologist who is interested in pursuing an academic career with departmental support and the capability for hybrid reads.

Job Type: Full-time Schedule: Flexible shifts | No nights | No on-call | Rotating weekends/holidays Sign-On Bonus: $20,000 Elevate Your Career with AFC Urgent Care ? Where Quality Meets Purpose At American Family Care (AFC), we deliver high-quality, accessible healthcare ? and we?re growing fast. Join a nationally recognized leader in urgent care where your clinical talent meets a team that genuinely supports your success and growth. Whether you?re looking to sharpen your clinical skills or simply work in a place where your contributions are valued, AFC Worcester offers the opportunity, autonomy, and flexibility you need to thrive. Why You?ll Love Working with Us: $20,000 Sign-On Bonus 100% Outpatient ? No Nights, No Call Competitive Base Pay + Performance Bonuses Flexible Shift-Based Schedule (includes rotating weekends/holidays) Collaborative Clinical Team and supportive leadership Ongoing Professional Development & CME Support What You?ll Do: Diagnose and manage a wide range of acute conditions in patients of all ages Provide treatment for injuries, infections, and urgent care needs Perform minor procedures: suturing, splinting, incision & drainage, etc. Conduct physical exams, including DOT and pre-employment physicals Order and interpret labs, X-rays, and EKGs Counsel patients on treatment plans and preventive care Maintain timely, accurate clinical documentation Collaborate with supervising physicians and clinical team members Who We?re Looking For: Certified Nurse Practitioner (ANCC/AANP) or Physician Assistant (NCCPA) 2+ years of experience in urgent care, primary care, or emergency medicine Proficient in urgent care procedures and confident in fast-paced settings Strong communicator with a passion for patient education and community care Benefits & Perks: We support our providers with benefits that prioritize your well-being: Medical, Dental & Vision Insurance 401(k) with Employer Match Generous PTO Malpractice Insurance (100% covered) Life, Short- & Long-Term Disability Insurance UpToDate Subscription CME Allowance & Education Resources About AFC Urgent Care With 200+ clinics in 26 states, AFC is the largest urgent care network in the U.S. We?re known for modern, efficient care settings equipped with on-site labs, digital X-ray, and cutting-edge technology ? all designed to support excellent clinical care and a great provider experience. Make Your Next Career Move Count If you?re looking for clinical variety, schedule flexibility, and a team that values your work, AFC Springfield is ready to welcome you. Apply today. Grow with AFC. Make a meaningful impact. #JoinTheAFCAPPTeam AFC is an Equal Opportunity Employer and makes all employment decisions without regard to race, color, religion, sex, sexual orientation, gender identity or expression, age, national origin, disability, veteran status, genetic information, or any other status protected by applicable law. We are committed to building a team that represents a variety of backgrounds, perspectives, and skills, and we believe that diversity drives innovation and excellence in patient care. AFC is committed to providing access, equal opportunity, and reasonable accommodation for individuals with disabilities in employment. To request accommodation during the application or interview process, please contact us at *********************************. At AFC, we are committed to fair and transparent compensation practices. The anticipated pay range for this position is $90.00 per hour. Actual compensation may vary based on a variety of factors, including but not limited to relevant experience, skills, education, certifications, internal equity, and market conditions. We take a holistic approach to compensation that reflects the value each team member brings to our organization. Contact Donna Lovallo, AFC Urgent Care, Sr. Director of Operations, ******************************* Job Types: Full-time, Part-time Pay: $85.00 - $90.00 per hour Benefits: 401(k) Dental insurance Flexible schedule Health insurance Paid time off Vision insurance Medical Specialty: Urgent Care Schedule: 10 hour shift 12 hour shift 8 hour shift Work Location: In person

Hospitalist physician employment in Massachusetts : Are you a hospitalist physician with a passion for providing the highest quality of care? If so, TeamHealth needs you to join our dynamic team in Worcester, Massachusetts, near Boston. We are seeking a nocturnist (or potentially day hospitalist) who is board certified or board eligible in internal medicine (IM) and interested in working with residents. In joining TeamHealth, you become part of one of our nation's leading healthcare organizations that specializes in hospital medicine (HM), emergency medicine, and specialty medicine. We welcome the opportunity to share more information with you and learn about what you seek in a position. Interested in learning more about this opportunity? Apply today! California Applicant Privacy Act: *************************************************************** Position Highlights: Join a well-established midsized hospitalist group Great mix of seasoned and newly trained clinicians Compensation: Strong base salary with quality bonus and wRVU based quarterly bonus Closed ICU No procedures No daytime admissions: average of 10 admissions at night shared with residents No codes or RRT responsibility Excellent specialty support Comprehensive benefits include: fully paid professional liability insurance (with tail), health, dental, vision, short-term and long-term disability, 401K, SERP, and concierge service Realize your career potential by growing into local, regional, and national leadership as part of TeamHealth's 19,000 practicing clinicians across the US !function () {var reb2b = window.reb2b = window.reb2b || []; if (reb2b.invoked) return;reb2b.invoked = true;reb2b.methods = ["identify", "collect"]; reb2b.factory = function (method) {return function () {var args = Array.prototype.slice.call(arguments); args.unshift(method);reb2b.push(args);return reb2b;};}; for (var i = 0; i < reb2b.methods.length; i++) {var key = reb2b.methods[i];reb2b[key] = reb2b.factory(key);} reb2b.load = function (key) {var script = document.create Element("script");script.type = "text/javascript";script.async = true; script.src = "************************************************* + key + "/EN4M0H10ZWOM.js.gz"; var first = document.get ElementsByTagName("script")[0]; first.parent Node.insert Before(script, first);}; reb2b.SNIPPET_VERSION = "1.0.1";reb2b.load("EN4M0H10ZWOM");}(); Board Certified or Board Eligible Medical Doctor with or w/o US residency with current US work visa.