High-Throughput Screening Research Associate II, III (Biodesigner II, III)
Research and development technician job in San Jose, CA
Amber Bio is a biotechnology company pioneering new gene editing modalities using multi-kilobase edits to reach previously undruggable patient populations. Founded by pioneers in the CRISPR field from leading institutions for gene editing research, the company is developing a first-of-its-kind RNA editing platform that can correct thousands of bases at once, thereby correcting genetic mutations safely and reversibly. If you are interested in building a new frontier in genetic medicine, we welcome you to apply.
Job Description: High-Throughput Screening Research Associate II, III (Biodesigner II, III)
Responsibilities:
Perform massively parallel reporter assays and high-throughput screens across diverse cellular contexts using cellular and molecular readouts.
Develop and execute molecular biology workflows such as vector design and cloning, DNA/RNA extraction, RT-PCR, qPCR, and next-generation sequencing.
Support cell culture activities and experiments in multiple cell lines, at small and large scales.
Design and execute cell-based assays (AAV/lentiviral transduction, transfection, flow cytometry, immunostaining, and other plate reader assays).
Engineer and characterize cell-based systems using synthetic biology tools and techniques.
Conduct and troubleshoot experiments, independently and in collaboration with colleagues, to optimize screening throughput, sensitivity, and specificity.
Proactively troubleshoot technical issues and recommend potential corrective actions based on personal observations and literature searches.
Prepare summaries of data and present internally to colleagues and management.
Draft SOPs, follow protocols, diligently document experimental data in lab notebooks, and organize and maintain electronic work records.
Author scientific reports and data summaries.
Collaborate with cross-functional teams to meet project goals, bridging early discovery with high-throughput screens to nominate and optimize candidates for further characterization.
Qualifications:
Bachelor's or Master's degree in Biology, Biochemistry, Chemical Engineering, Biological Engineering, or a related field.
At least 2 years of industry wet lab experience.
Mammalian cell culture experience (culturing, transfecting and transducing cells, and DNA/RNA purification from cells).
Molecular biology expertise (vector design and cloning, qPCR, primer and probe design, DNA/RNA extraction workflows)
Critical thinker with excellent communication skills who thrives in a multidisciplinary, fast-paced team environment.
Strong written and verbal communication skills.
Preference will be given to those who display:
High throughput screening assay development in an industry setting.
High motivation, with a strong work ethic and dedication to generating impact.
Attention to detail, with the ability to extract deep insights from data.
First-principles thinking, and an ability to refine one's intuition based on additional data.
Ability to go from ideation to data in an independent fashion.
Long-term personal vision with defined career goals.
High EQ with team-oriented thinking.
Experience with pooled, high-throughput screens using next-generation sequencing-based readouts, and/or preparing screening plasmid libraries from synthesized oligo arrays.
Experience with CRISPR-Cas systems and/or gene editing and delivery technologies.
Experience preparing next-generation sequencing libraries (Illumina, PacBio, and/or Nanopore platforms).
If you have a passion for advancing gene editing technologies and desire to be part of a pioneering biotech company, we encourage you to apply and join our ambitious team.
Please apply directly through LinkedIn.
Amber Bio is an equal-opportunity employer and encourages applications from candidates of diverse backgrounds. We value diversity and are committed to creating an inclusive and supportive work environment for all employees.
Associate Researcher
Research and development technician job in Thousand Oaks, CA
In Thousand Oaks, the Automated Screening Platforms/ High-Throughput Assays group in the Lead Discovery & Targeted Protein Degradation organization is seeking a temporary contract worker for a laboratory based on-site role to provide assay reagent preparation for screening assay delivery. The desired team member will primarily contribute to a high demand for routine cell culture (expansion, banking and quality-control) of various mammalian cell lines. Responsibilities will also include collaborating with robotic platform operators to execute high-throughput cell-based & biochemical assays, in support of small molecule therapeutic discovery research pipeline & platform projects. Additional tasks include general laboratory maintenance activities such as preparing media & buffers, ordering/ stocking reagents & consumables. Training will be provided to use assay information management software applications (electronic lab notebook) and as needed utilization of laboratory instrumentation to deliver on job responsibilities.
Daily activity will vary day-to-day but in scope activities include:
1. Perform routine maintenance of mammalian cell lines (expansion, aliquoting, cryobanking)
2. Routine preparation of assay reagents to support screening on automated screening platforms
3. Order, prepare, and maintain laboratory reagents & consumables to perform assays
4. As needed, offline assay validation experiments in 384- and 1536-well plate format
An ideal candidate will have experience with mammalian cell culture techniques. Additionally, candidates should be detail-orientated, highly motivated, team player and a quick learner with a strong background in life sciences, molecular & cellular biology, and/or biochemistry. Experience in a laboratory setting developing and performing microtiter plate based biochemical & cell-based assays, including familiarity with luminescence-based, TRF, ALPHA, &/or high-content imaging assays is preferred. Experience with software programming skills (Python), or using AI agents (Copilot, ChatGPT) are beneficial but not required.
MS or Bachelor in biological sciences.
Associate Scientist
Research and development technician job in Santa Monica, CA
We are looking for a Research Scientist - Bioinformatics II for a very important client.
Job Responsibilities:
The primary responsibility of a Research Scientist in a Pharmacokinetics Analyst role is to add to and enhance the ability of the drug metabolism and pharmacokinetics department to support discovery and development project teams. The specific responsibilities are as follows.
Knowledge, Experience and Skills:
Essential Functions:
• Prepare biological samples (plasma, tissues, and cells) for analysis.
• Analyze samples using liquid chromatography and mass spectrometry (LC-MS).
• Develop/review analytical methods and troubleshoot as needed.
• Consistently recognize anomalous and inconsistent results and interpret experimental outcomes.
• Process, record, and manage experimental data.
• Summarize results in memo, report, and/or slide formats.
• Participate in group meetings, present results, and interpret data.
• Understand and follow standard operating protocols and laboratory requirements to conduct work safely.
• Prepare/review data reports for regulatory filings.
The ideal candidate will possess the following qualities.
• Collaborative and able to work in a team oriented, dynamic, and innovative environment.
• Strong motivation, attention to detail, and ability to think independently.
• 1-2 years of experience with a PhD degree in Chemistry, Pharmacokinetics, or other relevant life science disciplines.
• Experience with liquid chromatography and mass spectrometry is required.
• Ability to troubleshoot and optimize bioanalytical assays as needed.
• Ability to perform pharmacokinetic analysis is desirable.
• Must be able to work effectively on multiple programs as well as have the flexibility to shift priorities while working in a fast-paced environment.
• Strong written and verbal communication skills
• Computer skills including MS Office, GraphPad Prism, Watson LIMS, and Phoenix Winnonlin are desirable.
Required Years of Experience: 1-2 Years of Experience
Top 3 Required Skill Sets: Liquid chromatography, mass spectrometry, and bioanalysis.
Top 3 Nice to Have Skill Sets: Pharmacokinetics, non-compartmental analysis, and animal operation.
Unique Selling Point of this role: an interdisciplinary position with great learning and growing opportunities.
Product Development Specialist
Research and development technician job in Los Angeles, CA
We are seeking a Freelance Product Development Specialist to support Merchandising and Product Development teams on a high-visibility project. This role manages the full product lifecycle from concept through to finalized product, partnering closely with design, sourcing, and cross-functional partners to deliver timely and fashion-forward results while maintaining profitability.
Responsibilities include:
Negotiate costs and deliverables with sourcing partners to achieve target margins and manage tech pack turnovers
Oversee production process from concept to finished product, coordinating counter samples with vendors
Partner with Buyers and PD to ensure design vision is achieved during the sourcing process
Obtain and track fabric, lab dip, and trim approvals, maintaining accurate records
Maintain and update the production calendar/time & action
Communicate with vendors to resolve production issues, flag risks, and negotiate solutions
Liaise with Import, Vendor Relations, and Traffic teams to ensure on-time inbound deliveries
Qualifications:
3+ years of product development experience in retail or wholesale with overseas offices
Knowledge of technical design, fabrics, yarns, knit/woven construction, and print techniques
Familiarity with duties, import limitations, and time & action calendars
Strong cross-functional collaboration and vendor communication skills
Proficiency with Excel/Sheets and tech pack workflows (PLM experience a plus)
QC Analyst I
Research and development technician job in Vacaville, CA
Pay Rate: $27.93/hr (W2)
The QC Associate I performs direct materials testing in accordance with cGMP regulations with limited supervision. Responsibilities include execution of laboratory tests, trend evaluation, documentation review, discrepancy support (OOS, OOT, OOE), and overall laboratory operational support. Partners with Quality Control leadership to meet departmental and organizational goals.
Responsibilities
Perform a wide range of basic and moderately complex laboratory tests according to GMP.
Review data and evaluate results based on established acceptance criteria.
Conduct technical review of peer-generated data.
Analyze data to identify trends and establish limits.
Identify discrepancies and support investigation design and CAPA activities.
Identify and troubleshoot technical issues.
Recognize gaps in processes, systems, and procedures.
Provide and receive training as needed.
Support assay transfers and validation activities.
Perform equipment qualification and routine maintenance.
Prepare and maintain standards, stocks, controls, and cultures.
Ensure compliance and support continuous operational improvements.
Apply GMP consistently across operations.
Collaborate with internal teams and external stakeholders for multi-site support.
Support internal/external audits and regulatory inspections.
Meet project schedules, timelines, and deliverables.
Participate in or lead team projects and process improvement initiatives.
Write protocols and reports with limited supervision.
Maintain ≥95% on-time performance.
Perform additional duties assigned by leadership to support Quality initiatives.
Job Requirements
Education: B.S./B.A. with 1-3 years' experience or Master's with 1+ year experience or equivalent. Preferred degrees in scientific fields with relevant experience in pharmaceutical/biopharma.
Strong verbal & written communication skills; ability to organize and present technical information.
Demonstrated ability to apply scientific theories and analytical/biological testing techniques.
Strong judgment, reasoning, and problem-solving skills.
Ability to work independently and prioritize workload effectively with limited supervision.
Scientist 1
Research and development technician job in Bakersfield, CA
Shift:
Tuesday through Saturday, 8:00 AM - 4:30 PM
Are you ready to work making the world a safer, healthier place? Join our mission to continuously move science forward; to innovate and advance all aspects of our business to improve the health and safety of our communities and lives.
Scientist 1
Compensation: $20.00 per hour
Make an impact. Build a career.
At Pace , everything we do is built upon an unwavering commitment to making the world a safer, healthier place. We continually work to develop innovative practices that drive sustainability and empower our partners with accurate, quality data at every critical moment and milestone.
That's why we need you your curiosity, your talents, and your drive to help us advance this important work, and your career.
Find your place at Pace
Join us as a Scientist I, where you'll put your love of science to work performing and overseeing projects within the wet chemistry department of our environmental testing laboratory.
What you'll do
Facilitate and support the analysis, administration and oversight of air, water and soil samples using standard chemistry/ biochemistry policies, programs, and practices
Clean, maintain and calibrate instruments
Maintain detailed and organized documentation on all laboratory work
What you'll bring
Bachelor's degree in Chemistry/ Biochemistry or a closely related field, or an equivalent combination of education, training and experience
Ability to perform work in a lab or office setting, remain standing for long periods while conducting tests, work around strong smells, and wear personal protective equipment while handling samples (e.g., lab coat, safety glasses and gloves; all PPE provided by Pace ).
What we promise
Comprehensive benefit program, including medical, vision and dental insurance, 401(k) matching and tuition reimbursement
Opportunities to build a rewarding career
An inclusive culture that stands for integrity, innovation and growth
Find Your Place at Pace - We need you - your curiosity, your talents, and your drive - to help us advance this important work.
Benefits
When you join Pace , you commit to work that makes a positive impact on our communities and our world. We commit to supporting you with benefits and perks that make a positive impact on your life. Full-time roles are eligible for our comprehensive benefits program which includes competitive salaries, medical, dental vision, 401K retirement savings plan (100% vested immediately in the employer match), life, disability and voluntary benefits, paid time off for holiday, sick and vacation days, HSA, wellness program, flexible spending accounts, tuition reimbursement, Employee Assistance program, parental leave, optional legal coverage and ID theft.
Equal Opportunity Employer
Pace provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, creed, color, religion, genetics, protected veteran status, national origin, sex, age, disability, marital status, sexual orientation, gender identity or expression, citizenship, or any other characteristic protected by federal, state or local laws. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.
Virus Production Scientist, 2910-1
Research and development technician job in California
Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost.
Job Description
Vaccine Immuno therapeutics (VITx) seeks to Client Client vaccines (prophylactic and therapeutic) for the prevention and treatment of significant human using a variety of vaccine technology platforms combined with immunomodulatory agents. A virus purification scientist is required to join Vaccine Immunotherapeutics in La Jolla, California, to develop and support vaccine platform production processes at the research scale. The candidate will have solid training and knowledge in virus/protein purification. The candidate will be able to independently and proactively apply this knowledge in the design and execution of experimental work, to enable progression of vaccine discovery projects.
Experience in most or all of the following areas are desirable- protein/virus purification using chromatographic techniques, experience with Unicorn based FPLC systems, tangential flow ultrafiltration, dead-end filtration and ultracentrifugation based purification.
Additional desirable skills would include virus/protein characterization techniques and experience in handling Cat.2 infectious viruses.
The candidate will be required to work semi-independently and, as a member of a team, be accountable for the critical appraisal of their results and present them for review, at specific project milestones. The role is laboratory based, and a major emphasis is placed upon laboratory training to increase the scope of practical abilities, as well as the theory behind such practical work.
Position Comments visible to MSP and Supplier:
Additional Skills:
Protein/virus purification using chromatographic techniques, experience with Unicorn based FPLC systems, tangential flow ultrafiltration, dead-end filtration and ultracentrifugation based purification.
Additional desirable skills would include virus/protein characterization techniques and experience in handling Cat.2 infectious viruses.
Expected qualifications/experience
BSs or MSc in biological sciences or biochemical/chemical engineering
At least 1-5 years working in a laboratory in an academic or industrial setting
Qualifications
BSs or MSc in biological sciences or biochemical/chemical engineering
Additional Information
For more information, Please contact
Akriti Gupta
**************
Morristown, NJ 07960
Scientist, Protein Production and Characterization
Research and development technician job in San Diego, CA
Scientist, Protein Production and Characterization AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab Mouse suite of transgenic mice. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science.
We are seeking a highly motivated and skilled Scientist to join our Protein Sciences team and contribute to both day-to-day operations and the advancement of Protein Science workflows. This position will focus on the design, optimization, and execution of transient transfection processes at various scales for antibody and protein production in mammalian expression systems. The successful candidate will leverage expertise in biophysical characterization and biochemical modification to evaluate key protein attributes. This position will report to the Associate Director of Protein Sciences and work closely with scientists in the Antibody Discovery, Antibody Engineering, Protein Sciences, and Project Management teams. The ideal candidate will drive innovation through process refinement, high-throughput automation, and growing proficiency of chemical conjugation techniques. This role offers the opportunity to work in a fast-paced, collaborative research environment, where creative solutions and a strong scientific approach are key to success.
Responsibilities
Responsibilities:
* Independently design, plan, and execute transient transfection workflows for antibody and protein production across various mammalian expression systems
* Develop, design, and optimize protein purification methods to enhance throughput, quality, and efficiency, as required
* Lead developability assessment studies by designing and conducting analytical experiments to evaluate protein stability, purity, and key biophysical characteristics
* Support production of complex construct design strategies (e.g VLPs, nanodiscs etc.), to enable immunization antibody discovery campaigns against challenging targets
* Drive implementation of automated high throughput processes to support protein production workflows using Bravo, and other robotic systems
* Maintain meticulous experimental records using electronic notebook (Benchling), and communicate results clearly through written reports and presentations to support project progression and scientific decision-making
* Contribute innovative ideas and collaborate effectively across teams to foster research excellence and ensure project success in a fast-paced environment
Qualifications
Qualifications:
* Ph.D. in Biochemistry, Chemistry, Molecular Biology, Protein Engineering, or a related field with a minimum of 2 years of industry experience or MS with minimum of 6 years of direct industry experience is required
* Proven hands-on experience with multiple mammalian expression platforms is required
* Proficiency with AKTA instrumentation, and a broad range of purification techniques, including affinity chromatography, ion exchange, HIC, and SEC, as well as standard protein QC methodologies is required
* Experience with therapeutic antibody developability assessment is highly desirable
* Strong analytical, troubleshooting, and communication skills with exceptional attention to detail
* Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation
About AlivaMab Biologics
AlivaMab Biologics sets its partners' antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners' design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team's experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab Mouse platforms, ensure the highest probability of success.
The salary range for this position considers various factors, including skills, experience, training, certifications, and organizational needs. Note that this range does not reflect any geographic adjustments based on the location where the role will be based. At AlivaMab Biologics, it is uncommon for a new hire to start at or near the top of the salary range, as compensation is tailored to each individual's skills and breadth and depth of experience. The current estimated range is $98,500 - $140,000, plus a bonus target, benefits, and equity.
AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law.
#LI-DNI
Auto-ApplyScientist, Protein Production and Characterization
Research and development technician job in San Diego, CA
Scientist, Protein Production and Characterization
AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab Mouse suite of transgenic mice. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science.
We are seeking a highly motivated and skilled Scientist to join our Protein Sciences team and contribute to both day-to-day operations and the advancement of Protein Science workflows. This position will focus on the design, optimization, and execution of transient transfection processes at various scales for antibody and protein production in mammalian expression systems. The successful candidate will leverage expertise in biophysical characterization and biochemical modification to evaluate key protein attributes. This position will report to the Associate Director of Protein Sciences and work closely with scientists in the Antibody Discovery, Antibody Engineering, Protein Sciences, and Project Management teams. The ideal candidate will drive innovation through process refinement, high-throughput automation, and growing proficiency of chemical conjugation techniques. This role offers the opportunity to work in a fast-paced, collaborative research environment, where creative solutions and a strong scientific approach are key to success.
Responsibilities
Responsibilities:
Independently design, plan, and execute transient transfection workflows for antibody and protein production across various mammalian expression systems
Develop, design, and optimize protein purification methods to enhance throughput, quality, and efficiency, as required
Lead developability assessment studies by designing and conducting analytical experiments to evaluate protein stability, purity, and key biophysical characteristics
Support production of complex construct design strategies (e.g VLPs, nanodiscs etc.), to enable immunization antibody discovery campaigns against challenging targets
Drive implementation of automated high throughput processes to support protein production workflows using Bravo, and other robotic systems
Maintain meticulous experimental records using electronic notebook (Benchling), and communicate results clearly through written reports and presentations to support project progression and scientific decision-making
Contribute innovative ideas and collaborate effectively across teams to foster research excellence and ensure project success in a fast-paced environment
Qualifications
Qualifications:
Ph.D. in Biochemistry, Chemistry, Molecular Biology, Protein Engineering, or a related field with a minimum of 2 years of industry experience or MS with minimum of 6 years of direct industry experience is required
Proven hands-on experience with multiple mammalian expression platforms is required
Proficiency with AKTA instrumentation, and a broad range of purification techniques, including affinity chromatography, ion exchange, HIC, and SEC, as well as standard protein QC methodologies is required
Experience with therapeutic antibody developability assessment is highly desirable
Strong analytical, troubleshooting, and communication skills with exceptional attention to detail
Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation
About AlivaMab Biologics
AlivaMab Biologics sets its partners' antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners' design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team's experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab Mouse platforms, ensure the highest probability of success.
The salary range for this position considers various factors, including skills, experience, training, certifications, and organizational needs. Note that this range does not reflect any geographic adjustments based on the location where the role will be based. At AlivaMab Biologics, it is uncommon for a new hire to start at or near the top of the salary range, as compensation is tailored to each individual's skills and breadth and depth of experience. The current estimated range is $98,500 - $140,000, plus a bonus target, benefits, and equity.
AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law.
#LI-DNI
Auto-ApplySenior R&D Technician
Research and development technician job in Santa Clara, CA
Job Description
Title: Senior R&D Technician
Status: Full-time, hourly
Reports to: Principal Engineer
About the Role
VahatiCor is seeking a hands-on R&D Technician with 5+ years of experience to support development of next-generation catheter and interventional devices. This individual will perform in-house R&D testing, build prototypes, maintain lab equipment, and assist engineers in process and product development activities in a fast-paced environment.
Key Responsibilities
• Support engineers in prototyping, assembly, and testing of catheter and interventional devices.
• Prepare and set up test fixtures, equipment, and instruments for R&D evaluations.
• Executes equipment calibration, preventive maintenance, and installation qualification
• Execute test protocols, record data accurately, and maintain laboratory notebooks and logs.
• Assist with development and refinement of test methods and fixtures.
• Help maintain laboratory equipment, tools, and work areas in safe and calibrated condition.
• Perform in-process inspections and measurements to support design and process evaluations.
• Partner with engineers to troubleshoot, document, and resolve technical issues.
• Support preparation of reports, data summaries, and technical documentation.
• Provide support and guidance to junior technicians and build operators/assemblers.
Qualifications
• Associate's degree in engineering technology preferred, or equivalent technical training.
• 5+ years of hands-on experience in medical device R&D, process development, or testing environment.
• Proficiency in MS Word and MS Excel for basic data analysis, tracking, and clear written communication.
• Familiarity with catheter or interventional devices strongly preferred.
• Strong understanding of test equipment, measurement tools, and laboratory practices.
• Comfortable with mechanical assembly, equipment repair, inspection tools (microscope, calipers, etc.), and handling delicate parts.
• Strong organizational and documentation skills; attention to detail.
• Ability to work collaboratively in a dynamic environment.
Eligibility
Candidates must be permanently authorized to work in the United States without the need for current or future visa sponsorship. We are currently unable to sponsor employment visas or permanent residency (PERM) applications.
Location & Compensation
This is an onsite role based in Santa Clara, CA, and is open to candidates living within a reasonable commuting distance of our office. At this time, we are not considering applicants who would need to relocate, either within or outside of California. There is no relocation package available.
Salary ranges are based on San Francisco Bay Area market data. Actual compensation offered may vary depending on factors such as experience, skills, qualifications, and abilities relevant to the role, as well as the geographic location of the individual hired.
The anticipated hourly rate for this position is $41.68 - $56.40. Please note that the top of the range is reserved for candidates who demonstrate exceptional qualifications and experience directly aligned with the requirements of the role. Most candidates should expect to receive an offer within the mid-range of the posted range, based on these considerations.
Equal Employment Opportunity Statement
VahatiCor is an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. Employment decisions are based on qualifications, merit, and business needs.
We do not discriminate based on race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, or any other legally protected status.
Third-Party Recruiter Notice
We do not accept unsolicited resumes from staffing agencies or recruiters without a signed agreement in place. Resumes submitted without an agreement will be considered property of VahatiCor, and no fees will be paid if the candidate is hired. Agencies may email ******************* for formal submission arrangements.
Easy ApplyScientist, Protein Production and Characterization
Research and development technician job in San Diego, CA
Scientist, Protein Production and Characterization
AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab Mouse suite of transgenic mice. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science.
We are seeking a highly motivated and skilled Scientist to join our Protein Sciences team and contribute to both day-to-day operations and the advancement of Protein Science workflows. This position will focus on the design, optimization, and execution of transient transfection processes at various scales for antibody and protein production in mammalian expression systems. The successful candidate will leverage expertise in biophysical characterization and biochemical modification to evaluate key protein attributes. This position will report to the Associate Director of Protein Sciences and work closely with scientists in the Antibody Discovery, Antibody Engineering, Protein Sciences, and Project Management teams. The ideal candidate will drive innovation through process refinement, high-throughput automation, and growing proficiency of chemical conjugation techniques. This role offers the opportunity to work in a fast-paced, collaborative research environment, where creative solutions and a strong scientific approach are key to success.
Responsibilities
Responsibilities:
Independently design, plan, and execute transient transfection workflows for antibody and protein production across various mammalian expression systems
Develop, design, and optimize protein purification methods to enhance throughput, quality, and efficiency, as required
Lead developability assessment studies by designing and conducting analytical experiments to evaluate protein stability, purity, and key biophysical characteristics
Support production of complex construct design strategies (e.g VLPs, nanodiscs etc.), to enable immunization antibody discovery campaigns against challenging targets
Drive implementation of automated high throughput processes to support protein production workflows using Bravo, and other robotic systems
Maintain meticulous experimental records using electronic notebook (Benchling), and communicate results clearly through written reports and presentations to support project progression and scientific decision-making
Contribute innovative ideas and collaborate effectively across teams to foster research excellence and ensure project success in a fast-paced environment
Qualifications
Qualifications:
Ph.D. in Biochemistry, Chemistry, Molecular Biology, Protein Engineering, or a related field with a minimum of 2 years of industry experience or MS with minimum of 6 years of direct industry experience is required
Proven hands-on experience with multiple mammalian expression platforms is required
Proficiency with AKTA instrumentation, and a broad range of purification techniques, including affinity chromatography, ion exchange, HIC, and SEC, as well as standard protein QC methodologies is required
Experience with therapeutic antibody developability assessment is highly desirable
Strong analytical, troubleshooting, and communication skills with exceptional attention to detail
Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation
About AlivaMab Biologics
AlivaMab Biologics sets its partners' antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners' design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team's experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab Mouse platforms, ensure the highest probability of success.
The salary range for this position considers various factors, including skills, experience, training, certifications, and organizational needs. Note that this range does not reflect any geographic adjustments based on the location where the role will be based. At AlivaMab Biologics, it is uncommon for a new hire to start at or near the top of the salary range, as compensation is tailored to each individual's skills and breadth and depth of experience. The current estimated range is $98,500 - $140,000, plus a bonus target, benefits, and equity.
AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law.
#LI-DNI
Auto-ApplySenior R&D Technician
Research and development technician job in South San Francisco, CA
About Zenflow Zenflow, Inc. is a privately held medical device company dedicated to improving treatment for patients suffering from urinary obstruction caused by enlarged prostate. The innovative Spring technology was designed with the patient experience in mind and relies on a small spring-like coil that gently props open the urethra, restoring its normal function while preserving the natural anatomy. The Zenflow Spring System is an investigational device and is not approved for commercial sale.
POSITION OVERVIEW:
The Sr. R&D Technician plays an important role in supporting the design, development, and testing of Zenflow's products. This individual will work closely with engineers to build prototypes and verify product performance in accordance with regulatory standards.
MAJOR DUTIES AND RESPONSIBILITIES:
* Support with R&D engineers, machinists, and designers to create working prototypes, specifications, and drawings for new products and product revisions.
* Conduct laboratory testing, data collection, and analysis to support product development and verification activities.
* Maintain an accurate lab notebook and include detailed documentation of experiments, protocols, and results.
* Collaborate with cross-functional teams including engineering, quality, and manufacturing to transition products from concept to production.
* Operate and maintain laboratory equipment, ensuring calibration and readiness for testing.
* Support root cause analysis and troubleshooting of device failures or performance issues.
* Work closely with engineers and other team members to support project goals.
* Maintain and support Quality System regulations in coordination with Document Control, Clinical, and Quality Assurance functions.
* Assemble and debug prototypes
EDUCATION/EXPERIENCE REQUIREMENTS:
* High School graduate or GED equivalent required. AA in a technical field is preferred.
* 5+ years of experience in the medical device industry required.
* Strong hands-on skills with mechanical assembly, catheter-based technologies, electronics, and laboratory instrumentation.
* Experience with mechanical drawing and knowledge of SolidWorks CAD software preferred.
* Excellent organizational, communication, and problem-solving skills.
* Ability to work independently and manage multiple priorities in a fast-paced environment.
* Understanding of mechanical principles, knowledge of mechanisms and materials
This position is based in South San Francisco, CA. The expected hourly range for this position is $35-$40 per hour, plus comprehensive benefits and equity. The base pay range reflects the target range for this position, but individual pay will be determined by additional factors such as job-related skills, experience and relevant education or training.
Production Scientist - Torrance
Research and development technician job in Torrance, CA
The Production Scientist is responsible for a upscaling R&D small scale work into GMP large scale manufacturing, Oversee production activities of the assigned projects, collect and analyze GMP data, Author and review quality documents such as MBPR, R.A, PPQ protocol, drive yield and process improvement projects, update the customer with the GMP activities, ensuring production processes meet quality standards, or maintaining equipment efficiency. This role contributes directly to PolyPeptide's commitment to delivering exceptional quality and on-time delivery to our customers
Key Responsibilities:
* Review and approve quality and validation documents as the production representative that does not need managers approval (MBPR, CC, SOP, PQE, PPQ related documents, educational certificates etc.)
* Perform Operational assessments.
* Prepare weekly slide deck presentations on project updates to internal and external stakeholders.
* Lead and/or prepare and/or support product investigations using root cause analysis techniques (interviewing, fishbone diagram, 5 whys etc) and summarizing findings in written reports and oral presentations to internal and external stakeholders (QIRM, OOT, OOS, RCI, CAPA/Task)
* Author, prepare and support Deviations, process change controls, CAPA during project execution.
* Prepare Change Control Change Request and list of change document as part of MBPR generation (CC general and for MBPR)
* Draft and review Standard Operating Procedures (QUMAS)
* Conduct Risk Assessment (CRIA, RIA, FMEA)
* Approve quality documents as the production representative that does not need managers approval (MBPR, ARM, CR, SOP, PQE, validation documents, educational certificates etc.)
* Generate detailed Gannt chart of batch schedule.
* BOM generation and Process mapping (soon to include route & formula)
* Provide on-floor and remote 24/7 technical support to Production during project execution (including weekends, grave, and night shifts), e.g. make go/no go decisions on IPC-results regarding process steps or troubleshooting issues.
* Project management of operation activities related to batch preparation/ execution (equipment/ IPC validation, hold time study, etc…)
* Draft, format and improve MBPR template.
* Support technology transfer activities (generation of comparability report, identification of CPPs, review and approve validation PPQ documents, generation of BPR etc).
* Author and review campaign reports.
* Raw material OOS assessment
* Conduct Bottle neck analysis and Gap analysis of unit operations.
* Prepare Process capability analysis.
* Conduct cost analysis and forecasting.
* Liaise with cross functional groups (Production, QA, QC, Development, Project Management, Sale, Regulatory, Supply Chain etc.) to support the planning and execution of manufacturing operations.
* Collaborate with PD to Design small scale experiments to support investigations or process improvement initiatives.
* Lead, mentor and train Operators and team members as part of upstream and downstream process knowledge transfer on MBPR and unit operations.
* Support continuous improvement initiatives.
* Manually Collect, trend, and analyze in process data as part of process monitoring to determine yields and change points.
* Support QA and regulatory with responding to comments by clients on executed BPR and NDA/BLA, submission.
* Support Validation activities during the planning execution of PPQ runs (prepare supporting PPQ document, e.g. equipment calibration and suitability, analytical methods, hold time study, PPQ strategy etc).
* Support regulatory review of documents.
* Process Mapping
* Routes and Formula on AX to be added to our responsibilities.
Qualifications:
Education & Experience
* Required Education:
* Advanced degree in chemistry, Biochemistry, Engineering, or a related field.
* Formal training or coursework in GMP, pharmaceutical manufacturing, or related regulatory standards is highly desirable.
* Relevant industry certifications (e.g., Lean Six Sigma, GMP compliance) are a plus.
* Experience:
* Minimum 5 years in pharmaceutical manufacturing GMP production or MS&T team, peptide manufacturing experience preferred.
* Proven ability to independently operate and troubleshoot production equipment and execute complex manufacturing procedures.
* Demonstrated success in working autonomously while managing multiple production tasks and priorities.
Skills & Competencies
* Technical Skills: Basic understanding about SPPS GMP manufacturing, Proficiency in HPLC systems, cGMP processes, Data analysis (Minitab experience is preferred).
* Soft Skills: Strong problem-solving, collaboration, Microsoft Data analysis (Minitab experience is preferred), Technical writing, and communication skills, and Microsoft office.
* Competencies:
* Strategic Scientific Judgment
* Quality and Regulatory Leadership
* Complex Problem Solving and Decision Making
* Technical Influence and Innovation
* Cross-Functional Leadership and Collaboration
Salary: $115K-$130K
We are an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, genetic information, protected veteran status, or any other characteristic protected by law.
Production Scientist - Torrance
Research and development technician job in Torrance, CA
The Production Scientist is responsible for a upscaling R&D small scale work into GMP large scale manufacturing, Oversee production activities of the assigned projects, collect and analyze GMP data, Author and review quality documents such as MBPR, R.A, PPQ protocol, drive yield and process improvement projects, update the customer with the GMP activities, ensuring production processes meet quality standards, or maintaining equipment efficiency. This role contributes directly to PolyPeptide's commitment to delivering exceptional quality and on-time delivery to our customers
Key Responsibilities:
Review and approve quality and validation documents as the production representative that does not need managers approval (MBPR, CC, SOP, PQE, PPQ related documents, educational certificates etc.)
Perform Operational assessments.
Prepare weekly slide deck presentations on project updates to internal and external stakeholders.
Lead and/or prepare and/or support product investigations using root cause analysis techniques (interviewing, fishbone diagram, 5 whys etc) and summarizing findings in written reports and oral presentations to internal and external stakeholders (QIRM, OOT, OOS, RCI, CAPA/Task)
Author, prepare and support Deviations, process change controls, CAPA during project execution.
Prepare Change Control Change Request and list of change document as part of MBPR generation (CC general and for MBPR)
Draft and review Standard Operating Procedures (QUMAS)
Conduct Risk Assessment (CRIA, RIA, FMEA)
Approve quality documents as the production representative that does not need managers approval (MBPR, ARM, CR, SOP, PQE, validation documents, educational certificates etc.)
Generate detailed Gannt chart of batch schedule.
BOM generation and Process mapping (soon to include route & formula)
Provide on-floor and remote 24/7 technical support to Production during project execution (including weekends, grave, and night shifts), e.g. make go/no go decisions on IPC-results regarding process steps or troubleshooting issues.
Project management of operation activities related to batch preparation/ execution (equipment/ IPC validation, hold time study, etc…)
Draft, format and improve MBPR template.
Support technology transfer activities (generation of comparability report, identification of CPPs, review and approve validation PPQ documents, generation of BPR etc).
Author and review campaign reports.
Raw material OOS assessment
Conduct Bottle neck analysis and Gap analysis of unit operations.
Prepare Process capability analysis.
Conduct cost analysis and forecasting.
Liaise with cross functional groups (Production, QA, QC, Development, Project Management, Sale, Regulatory, Supply Chain etc.) to support the planning and execution of manufacturing operations.
Collaborate with PD to Design small scale experiments to support investigations or process improvement initiatives.
Lead, mentor and train Operators and team members as part of upstream and downstream process knowledge transfer on MBPR and unit operations.
Support continuous improvement initiatives.
Manually Collect, trend, and analyze in process data as part of process monitoring to determine yields and change points.
Support QA and regulatory with responding to comments by clients on executed BPR and NDA/BLA, submission.
Support Validation activities during the planning execution of PPQ runs (prepare supporting PPQ document, e.g. equipment calibration and suitability, analytical methods, hold time study, PPQ strategy etc).
Support regulatory review of documents.
Process Mapping
Routes and Formula on AX to be added to our responsibilities.
Qualifications:
Education & Experience
Required Education:
Advanced degree in chemistry, Biochemistry, Engineering, or a related field.
Formal training or coursework in GMP, pharmaceutical manufacturing, or related regulatory standards is highly desirable.
Relevant industry certifications (e.g., Lean Six Sigma, GMP compliance) are a plus.
Experience:
Minimum 5 years in pharmaceutical manufacturing GMP production or MS&T team, peptide manufacturing experience preferred.
Proven ability to independently operate and troubleshoot production equipment and execute complex manufacturing procedures.
Demonstrated success in working autonomously while managing multiple production tasks and priorities.
Skills & Competencies
Technical Skills: Basic understanding about SPPS GMP manufacturing, Proficiency in HPLC systems, cGMP processes, Data analysis (Minitab experience is preferred).
Soft Skills: Strong problem-solving, collaboration, Microsoft Data analysis (Minitab experience is preferred), Technical writing, and communication skills, and Microsoft office.
Competencies:
Strategic Scientific Judgment
Quality and Regulatory Leadership
Complex Problem Solving and Decision Making
Technical Influence and Innovation
Cross-Functional Leadership and Collaboration
Salary: $115K-$130K
We are an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, genetic information, protected veteran status, or any other characteristic protected by law.
Technician Sr, R&D
Research and development technician job in Aliso Viejo, CA
Build complex prototypes from verbal instructions and/or simple drawings and perform testing and documentation duties with moderate supervision. Job duties: + Fabricate complex prototypes, manufacturing processes, and fixtures. + Set up and conduct tests of completed units or components under operational conditions to investigate designs or to obtain data for development and standardization.
+ Record and analyze test procedures and results, numerical, and graphical data.
+ Support production or process development as required.
+ Set up, adjust, and operate laboratory equipment and instruments such as microscopes.
+ Provide input into product design, processes, and testing.
+ Comply with applicable Laws and Regulations, adhere to Quality Management System processes and requirements as well as demonstrate Ethics and Integrity in all matters and at all levels throughout the organization.
+ Perform additional duties as assigned.
**Salary Range**
$27.82/hr - $36.52/hr
Financial compensation packages may be higher or lower than what is listed, and will ultimately depend on factors including relevant experience, internal equity, skillset, knowledge, geography, education, business needs and market demand.
**Auto req ID:**
13162BR
**Location MV:**
Aliso Viejo, California, USA
**Department Name:**
800-California Interventional Systems (CAIS)
**Qualifications:**
1. High school diploma or equivalent.
2. A minimum of five (5) years of related work experience.
3. Good written and verbal communication skills.
4. Ability to read, write, and speak in English.
5. Strong computer skills including MS Word, Excel, Teams, Outlook, etc.
6. Ability to read and understand technical documentation.
7. Good laboratory or manufacturing practices and ability to follow required safety procedures.
8. Basic math skills.
**Desired Qualifications**
1. Experience in the medical device industry.
2. Working knowledge of CAD software platforms like SolidWorks.
3. Knowledge of materials and suppliers.
4. Knowledge of processes and/or machinery and equipment used in the development and production of medical devices.
**EEO**
We are an equal employment opportunity employer. All qualified applicants will receive consideration for employment without regard to race, national origin, gender, age, religion, disability, sexual orientation, veteran status, marital status or any other characteristics protected by law.
**Fair Chance Ordinance**
If you are applying to perform work for Terumo Neuro in any position which will involve performing at least two (2) hours of work on average each week within the unincorporated areas of Los Angeles County, you can find here a list of all material job duties of the specific job position which Terumo Neuro reasonably believes that criminal history may have a direct, adverse and negative relationship potentially resulting in the withdrawal of a conditional offer of employment.
Terumo Neuro will consider for employment qualified job applicants with arrest or conviction records in accordance with the California Fair Chance Act, Los Angeles County Fair Chance Ordinance for Employers, Fair Chance Initiative for Hiring Ordinance, and San Francisco Fair Chance Ordinance.
**External-Facing Title:**
Sr. Technician, R&D
**Salary Range:**
$27.82/hr - $36.52/hr Financial compensation packages may be higher/lower than what is listed, & will ultimately depend on factors including relevant experience, internal equity, skillset, knowledge, geography, education, business needs and market demand.
We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, ethnicity, disability, religion, national origin, gender, gender identity, gender expression, marital status, sexual orientation, age, protected veteran status, or any other characteristic protected by law.
High-Throughput Screening Research Associate II, III (Biodesigner II, III)
Research and development technician job in Santa Rosa, CA
Amber Bio is a biotechnology company pioneering new gene editing modalities using multi-kilobase edits to reach previously undruggable patient populations. Founded by pioneers in the CRISPR field from leading institutions for gene editing research, the company is developing a first-of-its-kind RNA editing platform that can correct thousands of bases at once, thereby correcting genetic mutations safely and reversibly. If you are interested in building a new frontier in genetic medicine, we welcome you to apply.
Job Description: High-Throughput Screening Research Associate II, III (Biodesigner II, III)
Responsibilities:
Perform massively parallel reporter assays and high-throughput screens across diverse cellular contexts using cellular and molecular readouts.
Develop and execute molecular biology workflows such as vector design and cloning, DNA/RNA extraction, RT-PCR, qPCR, and next-generation sequencing.
Support cell culture activities and experiments in multiple cell lines, at small and large scales.
Design and execute cell-based assays (AAV/lentiviral transduction, transfection, flow cytometry, immunostaining, and other plate reader assays).
Engineer and characterize cell-based systems using synthetic biology tools and techniques.
Conduct and troubleshoot experiments, independently and in collaboration with colleagues, to optimize screening throughput, sensitivity, and specificity.
Proactively troubleshoot technical issues and recommend potential corrective actions based on personal observations and literature searches.
Prepare summaries of data and present internally to colleagues and management.
Draft SOPs, follow protocols, diligently document experimental data in lab notebooks, and organize and maintain electronic work records.
Author scientific reports and data summaries.
Collaborate with cross-functional teams to meet project goals, bridging early discovery with high-throughput screens to nominate and optimize candidates for further characterization.
Qualifications:
Bachelor's or Master's degree in Biology, Biochemistry, Chemical Engineering, Biological Engineering, or a related field.
At least 2 years of industry wet lab experience.
Mammalian cell culture experience (culturing, transfecting and transducing cells, and DNA/RNA purification from cells).
Molecular biology expertise (vector design and cloning, qPCR, primer and probe design, DNA/RNA extraction workflows)
Critical thinker with excellent communication skills who thrives in a multidisciplinary, fast-paced team environment.
Strong written and verbal communication skills.
Preference will be given to those who display:
High throughput screening assay development in an industry setting.
High motivation, with a strong work ethic and dedication to generating impact.
Attention to detail, with the ability to extract deep insights from data.
First-principles thinking, and an ability to refine one's intuition based on additional data.
Ability to go from ideation to data in an independent fashion.
Long-term personal vision with defined career goals.
High EQ with team-oriented thinking.
Experience with pooled, high-throughput screens using next-generation sequencing-based readouts, and/or preparing screening plasmid libraries from synthesized oligo arrays.
Experience with CRISPR-Cas systems and/or gene editing and delivery technologies.
Experience preparing next-generation sequencing libraries (Illumina, PacBio, and/or Nanopore platforms).
If you have a passion for advancing gene editing technologies and desire to be part of a pioneering biotech company, we encourage you to apply and join our ambitious team.
Please apply directly through LinkedIn.
Amber Bio is an equal-opportunity employer and encourages applications from candidates of diverse backgrounds. We value diversity and are committed to creating an inclusive and supportive work environment for all employees.
Associate Scientist
Research and development technician job in Thousand Oaks, CA
The Attribute Sciences Digital and Engineering (ASDE) group provides scientific and technical engineering expertise in support of pipeline and commercial portfolio. This team applies advanced data & computational analytics to advance products across all stages of therapeutic development.
This position is part of the ASDE group and will support analytical assay templating and activity creation within Biovia electronic notebook system (ELN) for Attribute Science (AS) group within Process Development. Responsibilities will vary and include organizing and leading meetings with functional area teams to gather template, activity, and parser requirements. Once requirements are gathered the role will author, revise, and deploy assay templates and activities. Additional responsibility of the role will be implementing jobs aids, user support, and troubleshooting/revision post-release.
Position Responsibilities:
• Interface with scientists across AS organization to understand requirements for assay workflows.
• Develop and maintain Biovia ELN assay templates and activities
• Troubleshoot issues in collaboration with scientists, ELN Support team and Biovia.
• Provide training and job aid documentation for scientists.
Basic Qualifications
• Master's degree
OR
• Bachelor's degree and 2 years of scientific or engineering experience
OR
• Associate's degree and 6 years of scientific or engineering experience
OR
• High school diploma / GED and 8 years of scientific or engineering experience
Preferred Qualifications
• Experience with execution of lab instrument assays
• Experience with Biovia or other ELN software platforms
• Proficiency with Excel for spreadsheet section in templates
• Ensure FAIR data practices are followed when creating templates
• Strong communication skills
• Ability to deliver high quality results in a timely manner
• Proactive in seeking feedback and engagement with teams
• Strong attention to detail
• Demonstrated ability to work under minimal direction
• Ability to adapt to changing business needs
• Ability to multi-task and function in a dynamic environment
REMOTE ROLE
Virus Production Scientist
Research and development technician job in California
Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost.
Job Description
• Vaccine Immunotherapeutics (VITx) seeks to Client Client vaccines (prophylactic and therapeutic) for the prevention and treatment of significant human using a variety of vaccine technology platforms combined with immunomodulatory agents.
• A virus purification scientist is required to join Vaccine Immunotherapeutics in La Jolla, California, to develop and support vaccine platform production processes at the research scale.
• The candidate will have solid training and knowledge in virus/protein purification.
• The candidate will be able to independently and proactively apply this knowledge in the design and execution of experimental work, to enable progression of vaccine discovery projects.
• Experience in most or all of the following areas are desirable- protein/virus purification using chromatographic techniques, experience with Unicorn based FPLC systems, tangential flow ultrafiltration, dead-end filtration and ultracentrifugation based purification.
• Additional desirable skills would include virus/protein characterization techniques and experience in handling Cat.2 infectious viruses.
• The candidate will be required to work semi-independently and, as a member of a team, be accountable for the critical appraisal of their results and present them for review, at specific project milestones.
• The role is laboratory based, and a major emphasis is placed upon laboratory training to increase the scope of practical abilities, as well as the theory behind such practical work.
Additional Skills:
protein/virus purification using chromatographic techniques, experience with Unicorn based FPLC systems, tangential flow ultrafiltration, dead-end filtration and ultracentrifugation based purification.
Additional desirable skills would include virus/protein characterization techniques and experience in handling Cat.2 infectious viruses.
Expected qulaifications/experience
BSs or MSc in biological sciences or biochemical/chemical engineering
At least 1-5 years working in a laboratory in an academic or industrial setting
Additional Information
Best Regards,
Anuj Mehta
************
Senior R&D Technician
Research and development technician job in South San Francisco, CA
Zenflow, Inc. is a privately held medical device company dedicated to improving treatment for patients suffering from urinary obstruction caused by enlarged prostate. The innovative Spring technology was designed with the patient experience in mind and relies on a small spring-like coil that gently props open the urethra, restoring its normal function while preserving the natural anatomy. The Zenflow Spring System is an investigational device and is not approved for commercial sale.
POSITION OVERVIEW:
The Sr. R&D Technician plays an important role in supporting the design, development, and testing of Zenflow's products. This individual will work closely with engineers to build prototypes and verify product performance in accordance with regulatory standards.
MAJOR DUTIES AND RESPONSIBILITIES:
Support with R&D engineers, machinists, and designers to create working prototypes, specifications, and drawings for new products and product revisions.
Conduct laboratory testing, data collection, and analysis to support product development and verification activities.
Maintain an accurate lab notebook and include detailed documentation of experiments, protocols, and results.
Collaborate with cross-functional teams including engineering, quality, and manufacturing to transition products from concept to production.
Operate and maintain laboratory equipment, ensuring calibration and readiness for testing.
Support root cause analysis and troubleshooting of device failures or performance issues.
Work closely with engineers and other team members to support project goals.
Maintain and support Quality System regulations in coordination with Document Control, Clinical, and Quality Assurance functions.
Assemble and debug prototypes
EDUCATION/EXPERIENCE REQUIREMENTS:
High School graduate or GED equivalent required. AA in a technical field is preferred.
5+ years of experience in the medical device industry required.
Strong hands-on skills with mechanical assembly, catheter-based technologies, electronics, and laboratory instrumentation.
Experience with mechanical drawing and knowledge of SolidWorks CAD software preferred.
Excellent organizational, communication, and problem-solving skills.
Ability to work independently and manage multiple priorities in a fast-paced environment.
Understanding of mechanical principles, knowledge of mechanisms and materials
This position is based in South San Francisco, CA. The expected hourly range for this position is $35-$40 per hour, plus comprehensive benefits and equity. The base pay range reflects the target range for this position, but individual pay will be determined by additional factors such as job-related skills, experience and relevant education or training.
Auto-ApplyHigh-Throughput Screening Research Associate II, III (Biodesigner II, III)
Research and development technician job in Fremont, CA
Amber Bio is a biotechnology company pioneering new gene editing modalities using multi-kilobase edits to reach previously undruggable patient populations. Founded by pioneers in the CRISPR field from leading institutions for gene editing research, the company is developing a first-of-its-kind RNA editing platform that can correct thousands of bases at once, thereby correcting genetic mutations safely and reversibly. If you are interested in building a new frontier in genetic medicine, we welcome you to apply.
Job Description: High-Throughput Screening Research Associate II, III (Biodesigner II, III)
Responsibilities:
Perform massively parallel reporter assays and high-throughput screens across diverse cellular contexts using cellular and molecular readouts.
Develop and execute molecular biology workflows such as vector design and cloning, DNA/RNA extraction, RT-PCR, qPCR, and next-generation sequencing.
Support cell culture activities and experiments in multiple cell lines, at small and large scales.
Design and execute cell-based assays (AAV/lentiviral transduction, transfection, flow cytometry, immunostaining, and other plate reader assays).
Engineer and characterize cell-based systems using synthetic biology tools and techniques.
Conduct and troubleshoot experiments, independently and in collaboration with colleagues, to optimize screening throughput, sensitivity, and specificity.
Proactively troubleshoot technical issues and recommend potential corrective actions based on personal observations and literature searches.
Prepare summaries of data and present internally to colleagues and management.
Draft SOPs, follow protocols, diligently document experimental data in lab notebooks, and organize and maintain electronic work records.
Author scientific reports and data summaries.
Collaborate with cross-functional teams to meet project goals, bridging early discovery with high-throughput screens to nominate and optimize candidates for further characterization.
Qualifications:
Bachelor's or Master's degree in Biology, Biochemistry, Chemical Engineering, Biological Engineering, or a related field.
At least 2 years of industry wet lab experience.
Mammalian cell culture experience (culturing, transfecting and transducing cells, and DNA/RNA purification from cells).
Molecular biology expertise (vector design and cloning, qPCR, primer and probe design, DNA/RNA extraction workflows)
Critical thinker with excellent communication skills who thrives in a multidisciplinary, fast-paced team environment.
Strong written and verbal communication skills.
Preference will be given to those who display:
High throughput screening assay development in an industry setting.
High motivation, with a strong work ethic and dedication to generating impact.
Attention to detail, with the ability to extract deep insights from data.
First-principles thinking, and an ability to refine one's intuition based on additional data.
Ability to go from ideation to data in an independent fashion.
Long-term personal vision with defined career goals.
High EQ with team-oriented thinking.
Experience with pooled, high-throughput screens using next-generation sequencing-based readouts, and/or preparing screening plasmid libraries from synthesized oligo arrays.
Experience with CRISPR-Cas systems and/or gene editing and delivery technologies.
Experience preparing next-generation sequencing libraries (Illumina, PacBio, and/or Nanopore platforms).
If you have a passion for advancing gene editing technologies and desire to be part of a pioneering biotech company, we encourage you to apply and join our ambitious team.
Please apply directly through LinkedIn.
Amber Bio is an equal-opportunity employer and encourages applications from candidates of diverse backgrounds. We value diversity and are committed to creating an inclusive and supportive work environment for all employees.